meta-int-snw-51382

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-55869 tai-screen-luciferase 4.752 5.69e-25 4.24e-04 6.99e-04 8 5
int-snw-51382 tai-screen-luciferase 7.286 3.65e-186 4.21e-10 1.27e-04 13 12
reg-snw-52 tai-screen-luciferase 4.903 9.49e-27 2.11e-04 3.66e-04 9 6
reg-snw-353274 tai-screen-luciferase 4.583 4.72e-23 8.88e-04 1.38e-03 9 4
reg-snw-5770 tai-screen-luciferase 4.418 2.91e-21 1.75e-03 2.57e-03 13 7
reg-snw-10198 tai-screen-luciferase 4.688 3.15e-24 5.65e-04 9.12e-04 9 5
reg-snw-988 tai-screen-luciferase 5.672 6.20e-37 3.20e-06 7.14e-06 5 3
reg-snw-6169 tai-screen-luciferase 4.851 3.99e-26 2.70e-04 4.60e-04 8 5
reg-snw-4609 tai-screen-luciferase 4.325 2.79e-20 2.52e-03 3.58e-03 14 8
reg-snw-84343 tai-screen-luciferase 4.236 2.24e-19 3.52e-03 4.83e-03 10 5
reg-snw-9967 tai-screen-luciferase 5.027 2.86e-28 1.15e-04 2.08e-04 8 6
reg-snw-57120 tai-screen-luciferase 4.450 1.33e-21 1.54e-03 2.29e-03 12 6
tai-screen-luciferase-meta-int-snw-51382 subnetwork

Genes (51)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree Transcription factor List-Gonzales GI Tai-Hits
ZNF445 353274 61.6294.5833TF--
COPA 1314 48-9.3955.672340TFYesYes
PAFAH1B1 5048 18-2.5834.58655TFYes-
CTSF 8722 8-3.9784.2361--Yes
TNFRSF8 943 19-4.1064.45015---
CUL4B 8450 21-2.8095.269142TF--
HSF1 3297 46-4.1795.027209TF-Yes
THRAP3 9967 52.5075.02722---
COPB2 9276 48-13.1689.06341-YesYes
CKAP5 9793 46-7.2145.672130TFYesYes
RB1 5925 21-2.0854.707351TF--
PTPN1 5770 102.0674.4181---
EIF2S2 8894 31-4.3205.672103-Yes-
CDC42 998 44-6.9604.707276-YesYes
UTP18 51096 8-1.7094.236106TF--
RPS11 6205 44-6.5887.555175-Yes-
MYC 4609 9-1.9204.32577TF--
SIVA1 10572 5-3.7595.02789TF-Yes
NME2 4831 24-3.0344.32553TF--
RPS6 6194 44-5.6038.046217-Yes-
MRPS12 6183 35-5.4215.516341TFYes-
TLK2 11011 21-4.0115.67214---
GCN1L1 10985 10-2.9184.41843TF--
YBX1 4904 24-3.0335.516296TF--
RAN 5901 38-3.8094.325258-YesYes
MPHOSPH9 10198 52.0554.68841---
SERBP1 26135 35-4.6125.516106--Yes
RPS13 6207 43-6.5897.555174-Yes-
CDC5L 988 34-3.4195.672155TF--
HES4 57801 19-4.1534.45010---
HPS3 84343 8-1.5164.23641---
THAP11 57215 9-3.6734.3253TF-Yes
GOPC 57120 191.7494.45068---
WDR18 57418 62.3224.752213TF--
RPL38 6169 6-1.9924.8514-Yes-
RPS24 6229 46-7.0348.389217-Yes-
HDAC8 55869 61.2284.75216---
ODC1 4953 9-2.5034.32512---
RPS9 6203 45-7.1277.555140-Yes-
RPS4X 6191 44-6.7477.555263-Yes-
COPZ1 22818 48-8.3019.06313-YesYes
ATP6V1D 51382 30-4.1317.286149---
BRCA2 675 8-1.9914.236111TF--
PSMD3 5709 22-3.9356.408201TF-Yes
PSMD8 5714 15-2.9164.418143---
RPS14 6208 23-4.8037.011204-Yes-
RPS19 6223 21-4.7014.752102-Yes-
UACA 55075 5-2.1774.68876TF--
ACP1 52 8-2.2304.90346---
RPS26 6231 43-7.4788.04660-Yes-
ARCN1 372 48-8.2329.063118-YesYes

Interactions (115)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
CDC5L 988 HDAC8 55869 pd > reg.ITFP.txt: no annot
NME2 4831 RPS19 6223 pp -- int.Proteinpedia: Mass spectrometry
MRPS12 6183 THRAP3 9967 pd > reg.ITFP.txt: no annot
ACP1 52 WDR18 57418 pd < reg.ITFP.txt: no annot
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
MYC 4609 PSMD3 5709 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct, KOCH_MYC
RPS11 6205 RPS19 6223 pp -- int.I2D: IntAct_Yeast
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 ATP6V1D 51382 pp -- int.I2D: YeastLow
COPA 1314 PSMD8 5714 pp -- int.I2D: YeastLow
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
MRPS12 6183 SIVA1 10572 pd <> reg.ITFP.txt: no annot
CDC5L 988 CUL4B 8450 pd <> reg.ITFP.txt: no annot
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 HPS3 84343 pd > reg.ITFP.txt: no annot
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
RAN 5901 WDR18 57418 pd < reg.ITFP.txt: no annot
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RB1 5925 GOPC 57120 pd > reg.ITFP.txt: no annot
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
MYC 4609 COPB2 9276 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
HDAC8 55869 WDR18 57418 pd < reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
ARCN1 372 MYC 4609 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACP1 52 MRPS12 6183 pd < reg.ITFP.txt: no annot
YBX1 4904 SERBP1 26135 pd > reg.ITFP.txt: no annot
MYC 4609 ODC1 4953 pd > reg.TRANSFAC.txt: no annot
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
YBX1 4904 RB1 5925 pd < reg.pazar.txt: no annot
CDC5L 988 ZNF445 353274 pd <> reg.ITFP.txt: no annot
UTP18 51096 HPS3 84343 pd > reg.ITFP.txt: no annot
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
CKAP5 9793 HDAC8 55869 pd > reg.ITFP.txt: no annot
SIVA1 10572 WDR18 57418 pd <> reg.ITFP.txt: no annot
MYC 4609 YBX1 4904 pd > reg.TRANSFAC.txt: no annot
MYC 4609 YBX1 4904 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
HSF1 3297 UACA 55075 pd <> reg.ITFP.txt: no annot
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
MPHOSPH9 10198 UACA 55075 pd < reg.ITFP.txt: no annot
MRPS12 6183 WDR18 57418 pd <> reg.ITFP.txt: no annot
CUL4B 8450 GOPC 57120 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 GOPC 57120 pd > reg.ITFP.txt: no annot
YBX1 4904 PTPN1 5770 pd > reg.TRANSFAC.txt: no annot
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 GCN1L1 10985 pd <> reg.ITFP.txt: no annot
PSMD3 5709 UTP18 51096 pp -- int.I2D: IntAct_Yeast
MYC 4609 RB1 5925 pp -- int.I2D: BCI, HPRD, BioGrid;
int.Transfac: -;
int.Ravasi: -;
int.HPRD: in vivo
MYC 4609 RAN 5901 pd > reg.ITFP.txt: no annot
RPS13 6207 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 PSMD8 5714 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, IntAct_Yeast, INTEROLOG, Krogan_Core, YeastHigh
MYC 4609 THAP11 57215 pd < reg.TRANSFAC.txt: no annot
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 PSMD8 5714 pd > reg.ITFP.txt: no annot
RAN 5901 GCN1L1 10985 pp -- int.I2D: YeastLow
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
PSMD8 5714 MRPS12 6183 pd < reg.ITFP.txt: no annot
CDC5L 988 MPHOSPH9 10198 pd > reg.ITFP.txt: no annot
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
PSMD8 5714 ATP6V1D 51382 pp -- int.I2D: YeastLow
MPHOSPH9 10198 UTP18 51096 pd < reg.ITFP.txt: no annot
BRCA2 675 CTSF 8722 pd > reg.ITFP.txt: no annot
RPS14 6208 UTP18 51096 pd < reg.ITFP.txt: no annot
ACP1 52 CDC5L 988 pd < reg.ITFP.txt: no annot
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
CDC42 998 GOPC 57120 pp -- int.I2D: BioGrid
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
THRAP3 9967 SIVA1 10572 pd < reg.ITFP.txt: no annot
NME2 4831 RPL38 6169 pp -- int.Proteinpedia: Mass spectrometry
MYC 4609 NME2 4831 pd < reg.TRANSFAC.txt: no annot
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
MYC 4609 GCN1L1 10985 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid, IntAct, KOCH_MYC, SOURAV_MAPK_HIGH
CDC5L 988 TLK2 11011 pd > reg.ITFP.txt: no annot
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RPS19 6223 WDR18 57418 pd < reg.ITFP.txt: no annot
CDC5L 988 YBX1 4904 pd <> reg.ITFP.txt: no annot
MRPS12 6183 HDAC8 55869 pd > reg.ITFP.txt: no annot
YBX1 4904 MRPS12 6183 pd <> reg.ITFP.txt: no annot
COPA 1314 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 GCN1L1 10985 pp -- int.I2D: BioGrid
CDC5L 988 GOPC 57120 pd > reg.ITFP.txt: no annot
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CKAP5 9793 MPHOSPH9 10198 pd > reg.ITFP.txt: no annot
BRCA2 675 HPS3 84343 pd > reg.ITFP.txt: no annot
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
CDC5L 988 RPL38 6169 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
COPA 1314 HPS3 84343 pd > reg.ITFP.txt: no annot
RAN 5901 ATP6V1D 51382 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
CDC5L 988 THRAP3 9967 pd > reg.ITFP.txt: no annot
PSMD3 5709 GCN1L1 10985 pd <> reg.ITFP.txt: no annot
PSMD3 5709 MRPS12 6183 pd <> reg.ITFP.txt: no annot
MYC 4609 ATP6V1D 51382 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot

Related GO terms (607)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit2.66e-154.34e-116.20792139
GO:0019058viral life cycle4.90e-148.00e-104.9361125115
GO:0019083viral transcription5.53e-149.03e-105.304102281
GO:0006415translational termination1.16e-131.90e-095.201102287
GO:0006413translational initiation2.11e-133.44e-094.7481127131
GO:0006414translational elongation2.32e-133.78e-095.105102293
GO:0006412translation2.41e-133.93e-094.1461329235
GO:0003735structural constituent of ribosome4.78e-137.80e-094.6421124141
GO:0006614SRP-dependent cotranslational protein targeting to membrane7.30e-131.19e-084.9441022104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.86e-123.03e-084.8111022114
GO:0016071mRNA metabolic process3.13e-125.10e-084.1061229223
GO:0016070RNA metabolic process1.04e-111.70e-073.9591229247
GO:0044822poly(A) RNA binding2.28e-113.72e-072.57020421078
GO:0016032viral process5.46e-118.91e-073.1521537540
GO:0010467gene expression1.00e-101.63e-062.9361636669
GO:0016020membrane4.12e-106.73e-062.07623481746
GO:0015935small ribosomal subunit1.47e-092.39e-056.5565917
GO:0005829cytosol4.80e-097.84e-051.69926742562
GO:0005840ribosome2.73e-084.45e-045.02461059
GO:0048205COPI coating of Golgi vesicle5.92e-089.66e-046.6224613
GO:0030126COPI vesicle coat5.92e-089.66e-046.6224613
GO:0070062extracellular vesicular exosome9.48e-081.55e-031.61024512516
GO:0044267cellular protein metabolic process2.84e-074.64e-032.8301129495
GO:0000028ribosomal small subunit assembly9.97e-071.63e-027.100337
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.02e-061.66e-025.6784625
GO:0005925focal adhesion1.88e-063.07e-022.961923370
GO:0005737cytoplasm2.76e-064.50e-021.17228653976
GO:0042274ribosomal small subunit biogenesis6.20e-061.01e-016.3223612
GO:0005730nucleolus7.54e-061.23e-011.69217361684
GO:0042176regulation of protein catabolic process1.56e-052.55e-015.9073416
GO:0036464cytoplasmic ribonucleoprotein granule4.25e-056.93e-015.4483522
GO:0006417regulation of translation4.40e-057.18e-014.3454463
GO:0030490maturation of SSU-rRNA5.72e-059.34e-017.322224
GO:0071922regulation of cohesin localization to chromatin5.72e-059.34e-017.322224
GO:0019843rRNA binding7.97e-051.00e+005.1523427
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)9.52e-051.00e+007.000235
GO:0033119negative regulation of RNA splicing9.52e-051.00e+007.000225
GO:0051219phosphoprotein binding1.34e-041.00e+004.9073432
GO:0045182translation regulator activity1.42e-041.00e+006.737226
GO:0006924activation-induced cell death of T cells1.42e-041.00e+006.737226
GO:0007097nuclear migration1.99e-041.00e+006.515227
GO:0006364rRNA processing2.27e-041.00e+003.7374896
GO:0030521androgen receptor signaling pathway2.82e-041.00e+004.5493341
GO:0030529ribonucleoprotein complex4.38e-041.00e+003.48948114
GO:0006521regulation of cellular amino acid metabolic process5.08e-041.00e+004.2633550
GO:0005838proteasome regulatory particle6.19e-041.00e+005.7372312
GO:0005515protein binding6.27e-041.00e+000.69531876127
GO:0005813centrosome6.29e-041.00e+002.50269339
GO:0061024membrane organization1.11e-031.00e+003.132411146
GO:0000082G1/S transition of mitotic cell cycle1.22e-031.00e+003.093411150
GO:0006891intra-Golgi vesicle-mediated transport1.26e-031.00e+005.2352317
GO:0022624proteasome accessory complex1.26e-031.00e+005.2352417
GO:0003697single-stranded DNA binding1.30e-031.00e+003.7983469
GO:0043015gamma-tubulin binding1.42e-031.00e+005.1522218
GO:0000278mitotic cell cycle1.44e-031.00e+002.270616398
GO:0043473pigmentation1.75e-031.00e+005.0002220
GO:0006886intracellular protein transport2.07e-031.00e+002.88746173
GO:0043234protein complex2.39e-031.00e+002.41559300
GO:0008135translation factor activity, nucleic acid binding2.53e-031.00e+004.7372424
GO:0005634nucleus2.67e-031.00e+000.72925664828
GO:0005844polysome2.74e-031.00e+004.6782225
GO:0045931positive regulation of mitotic cell cycle2.97e-031.00e+004.6222226
GO:0045556positive regulation of TRAIL biosynthetic process3.12e-031.00e+008.322111
GO:0000235astral microtubule3.12e-031.00e+008.322111
GO:0033176proton-transporting V-type ATPase complex3.12e-031.00e+008.322111
GO:0033291eukaryotic 80S initiation complex3.12e-031.00e+008.322111
GO:0090230regulation of centromere complex assembly3.12e-031.00e+008.322111
GO:0004586ornithine decarboxylase activity3.12e-031.00e+008.322111
GO:0004673protein histidine kinase activity3.12e-031.00e+008.322111
GO:1990264peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity3.12e-031.00e+008.322111
GO:003446390S preribosome assembly3.12e-031.00e+008.322111
GO:0090096positive regulation of metanephric cap mesenchymal cell proliferation3.12e-031.00e+008.322111
GO:0022605oogenesis stage3.12e-031.00e+008.322111
GO:0043004cytoplasmic sequestering of CFTR protein3.12e-031.00e+008.322111
GO:0018106peptidyl-histidine phosphorylation3.12e-031.00e+008.322111
GO:0033593BRCA2-MAGE-D1 complex3.12e-031.00e+008.322111
GO:0005175CD27 receptor binding3.12e-031.00e+008.322111
GO:0021691cerebellar Purkinje cell layer maturation3.12e-031.00e+008.322111
GO:0033387putrescine biosynthetic process from ornithine3.12e-031.00e+008.322111
GO:0051660establishment of centrosome localization3.12e-031.00e+008.322111
GO:0046469platelet activating factor metabolic process3.12e-031.00e+008.322111
GO:0019901protein kinase binding3.15e-031.00e+002.32259320
GO:0010332response to gamma radiation3.68e-031.00e+004.4642229
GO:0007093mitotic cell cycle checkpoint4.20e-031.00e+004.3682231
GO:0048471perinuclear region of cytoplasm5.58e-031.00e+001.87669523
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process5.64e-031.00e+004.1522236
GO:0007067mitotic nuclear division5.81e-031.00e+002.47047231
GO:0071987WD40-repeat domain binding6.24e-031.00e+007.322112
GO:0060661submandibular salivary gland formation6.24e-031.00e+007.322112
GO:0036035osteoclast development6.24e-031.00e+007.322112
GO:0002762negative regulation of myeloid leukocyte differentiation6.24e-031.00e+007.322112
GO:1902202regulation of hepatocyte growth factor receptor signaling pathway6.24e-031.00e+007.322112
GO:0044346fibroblast apoptotic process6.24e-031.00e+007.322112
GO:0071338positive regulation of hair follicle cell proliferation6.24e-031.00e+007.322112
GO:0051081nuclear envelope disassembly6.24e-031.00e+007.322112
GO:0002176male germ cell proliferation6.24e-031.00e+007.322112
GO:0072422signal transduction involved in DNA damage checkpoint6.24e-031.00e+007.322112
GO:0001672regulation of chromatin assembly or disassembly6.24e-031.00e+007.322112
GO:0035791platelet-derived growth factor receptor-beta signaling pathway6.24e-031.00e+007.322112
GO:0090135actin filament branching6.24e-031.00e+007.322112
GO:0031134sister chromatid biorientation6.24e-031.00e+007.322112
GO:0060265positive regulation of respiratory burst involved in inflammatory response6.24e-031.00e+007.322112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis6.24e-031.00e+007.322112
GO:0030218erythrocyte differentiation6.26e-031.00e+004.0742238
GO:0050681androgen receptor binding6.26e-031.00e+004.0742238
GO:0005654nucleoplasm6.30e-031.00e+001.3959261095
GO:0021766hippocampus development6.59e-031.00e+004.0372339
GO:0008134transcription factor binding7.23e-031.00e+002.38045246
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding9.35e-031.00e+006.737113
GO:0043293apoptosome9.35e-031.00e+006.737113
GO:0003161cardiac conduction system development9.35e-031.00e+006.737113
GO:0071459protein localization to chromosome, centromeric region9.35e-031.00e+006.737113
GO:0048318axial mesoderm development9.35e-031.00e+006.737113
GO:0051154negative regulation of striated muscle cell differentiation9.35e-031.00e+006.737113
GO:0032204regulation of telomere maintenance9.35e-031.00e+006.737113
GO:0097443sorting endosome9.35e-031.00e+006.737113
GO:0010484H3 histone acetyltransferase activity9.35e-031.00e+006.737113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle9.35e-031.00e+006.737113
GO:0045505dynein intermediate chain binding9.35e-031.00e+006.737113
GO:0051683establishment of Golgi localization9.35e-031.00e+006.737123
GO:0031084BLOC-2 complex9.35e-031.00e+006.737113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity9.35e-031.00e+006.737113
GO:0005850eukaryotic translation initiation factor 2 complex9.35e-031.00e+006.737113
GO:0000056ribosomal small subunit export from nucleus9.35e-031.00e+006.737123
GO:0060266negative regulation of respiratory burst involved in inflammatory response9.35e-031.00e+006.737113
GO:0021540corpus callosum morphogenesis9.35e-031.00e+006.737113
GO:0008344adult locomotory behavior9.46e-031.00e+003.7672247
GO:0008286insulin receptor signaling pathway1.03e-021.00e+002.73734144
GO:0035690cellular response to drug1.07e-021.00e+003.6782350
GO:0043066negative regulation of apoptotic process1.11e-021.00e+001.886514433
GO:0042981regulation of apoptotic process1.17e-021.00e+002.66937151
GO:0034191apolipoprotein A-I receptor binding1.24e-021.00e+006.322114
GO:0007000nucleolus organization1.24e-021.00e+006.322124
GO:0048478replication fork protection1.24e-021.00e+006.322114
GO:0060684epithelial-mesenchymal cell signaling1.24e-021.00e+006.322114
GO:0051835positive regulation of synapse structural plasticity1.24e-021.00e+006.322114
GO:0043550regulation of lipid kinase activity1.24e-021.00e+006.322114
GO:0090231regulation of spindle checkpoint1.24e-021.00e+006.322114
GO:0072384organelle transport along microtubule1.24e-021.00e+006.322124
GO:0048664neuron fate determination1.24e-021.00e+006.322114
GO:0045682regulation of epidermis development1.24e-021.00e+006.322114
GO:0045656negative regulation of monocyte differentiation1.24e-021.00e+006.322114
GO:0000055ribosomal large subunit export from nucleus1.24e-021.00e+006.322114
GO:0035189Rb-E2F complex1.24e-021.00e+006.322114
GO:0034088maintenance of mitotic sister chromatid cohesion1.24e-021.00e+006.322114
GO:0034349glial cell apoptotic process1.24e-021.00e+006.322114
GO:0009991response to extracellular stimulus1.24e-021.00e+006.322114
GO:0050679positive regulation of epithelial cell proliferation1.24e-021.00e+003.5672254
GO:0006879cellular iron ion homeostasis1.37e-021.00e+003.4892257
GO:0000502proteasome complex1.42e-021.00e+003.4642458
GO:0070934CRD-mediated mRNA stabilization1.55e-021.00e+006.000115
GO:0036336dendritic cell migration1.55e-021.00e+006.000115
GO:0035088establishment or maintenance of apical/basal cell polarity1.55e-021.00e+006.000115
GO:0051782negative regulation of cell division1.55e-021.00e+006.000115
GO:0048667cell morphogenesis involved in neuron differentiation1.55e-021.00e+006.000115
GO:0031256leading edge membrane1.55e-021.00e+006.000115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.55e-021.00e+006.000115
GO:0031023microtubule organizing center organization1.55e-021.00e+006.000115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.55e-021.00e+006.000115
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.76e-021.00e+003.3002665
GO:0045893positive regulation of transcription, DNA-templated1.76e-021.00e+001.71658487
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.76e-021.00e+003.3002665
GO:0034641cellular nitrogen compound metabolic process1.78e-021.00e+002.43935177
GO:0005882intermediate filament1.81e-021.00e+003.2782366
GO:0043353enucleate erythrocyte differentiation1.86e-021.00e+005.737116
GO:0007143female meiotic division1.86e-021.00e+005.737116
GO:0002309T cell proliferation involved in immune response1.86e-021.00e+005.737116
GO:0032873negative regulation of stress-activated MAPK cascade1.86e-021.00e+005.737116
GO:0060789hair follicle placode formation1.86e-021.00e+005.737116
GO:0008090retrograde axon cargo transport1.86e-021.00e+005.737116
GO:0006333chromatin assembly or disassembly1.86e-021.00e+005.737116
GO:0048554positive regulation of metalloenzyme activity1.86e-021.00e+005.737116
GO:0030141secretory granule1.86e-021.00e+003.2562267
GO:0010485H4 histone acetyltransferase activity1.86e-021.00e+005.737116
GO:0019215intermediate filament binding1.86e-021.00e+005.737116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.86e-021.00e+005.737116
GO:0070937CRD-mediated mRNA stability complex1.86e-021.00e+005.737116
GO:0001667ameboidal-type cell migration1.86e-021.00e+005.737116
GO:0048026positive regulation of mRNA splicing, via spliceosome1.86e-021.00e+005.737116
GO:0000974Prp19 complex1.86e-021.00e+005.737116
GO:0034452dynactin binding1.86e-021.00e+005.737116
GO:0071204histone pre-mRNA 3'end processing complex1.86e-021.00e+005.737116
GO:0006338chromatin remodeling1.91e-021.00e+003.2352268
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.02e-021.00e+003.1932870
GO:0006893Golgi to plasma membrane transport2.17e-021.00e+005.515117
GO:2001022positive regulation of response to DNA damage stimulus2.17e-021.00e+005.515117
GO:0009142nucleoside triphosphate biosynthetic process2.17e-021.00e+005.515117
GO:0060136embryonic process involved in female pregnancy2.17e-021.00e+005.515117
GO:0043497regulation of protein heterodimerization activity2.17e-021.00e+005.515117
GO:0050658RNA transport2.17e-021.00e+005.515117
GO:0048027mRNA 5'-UTR binding2.17e-021.00e+005.515117
GO:0061512protein localization to cilium2.17e-021.00e+005.515117
GO:0003334keratinocyte development2.17e-021.00e+005.515117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.17e-021.00e+005.515117
GO:0070914UV-damage excision repair2.17e-021.00e+005.515117
GO:0001961positive regulation of cytokine-mediated signaling pathway2.17e-021.00e+005.515117
GO:0034101erythrocyte homeostasis2.17e-021.00e+005.515117
GO:0004726non-membrane spanning protein tyrosine phosphatase activity2.17e-021.00e+005.515117
GO:0030157pancreatic juice secretion2.17e-021.00e+005.515117
GO:0030948negative regulation of vascular endothelial growth factor receptor signaling pathway2.17e-021.00e+005.515117
GO:0017145stem cell division2.17e-021.00e+005.515117
GO:0000930gamma-tubulin complex2.17e-021.00e+005.515117
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.18e-021.00e+003.1322673
GO:0003729mRNA binding2.18e-021.00e+003.1322373
GO:0000785chromatin2.18e-021.00e+003.1322273
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.24e-021.00e+003.1132874
GO:0060070canonical Wnt signaling pathway2.30e-021.00e+003.0932275
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.41e-021.00e+003.0552677
GO:0031512motile primary cilium2.47e-021.00e+005.322118
GO:0003723RNA binding2.47e-021.00e+001.850410355
GO:0006183GTP biosynthetic process2.47e-021.00e+005.322118
GO:0007289spermatid nucleus differentiation2.47e-021.00e+005.322118
GO:0051489regulation of filopodium assembly2.47e-021.00e+005.322118
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway2.47e-021.00e+005.322118
GO:0003993acid phosphatase activity2.47e-021.00e+005.322118
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.53e-021.00e+003.0182879
GO:0010629negative regulation of gene expression2.59e-021.00e+003.0002280
GO:0097284hepatocyte apoptotic process2.78e-021.00e+005.152119
GO:0000075cell cycle checkpoint2.78e-021.00e+005.152119
GO:0006241CTP biosynthetic process2.78e-021.00e+005.152119
GO:0021895cerebral cortex neuron differentiation2.78e-021.00e+005.152119
GO:0014075response to amine2.78e-021.00e+005.152119
GO:0006228UTP biosynthetic process2.78e-021.00e+005.152119
GO:0090136epithelial cell-cell adhesion2.78e-021.00e+005.152129
GO:0032319regulation of Rho GTPase activity2.78e-021.00e+005.152119
GO:0042347negative regulation of NF-kappaB import into nucleus2.78e-021.00e+005.152119
GO:0003700sequence-specific DNA binding transcription factor activity2.84e-021.00e+001.36069748
GO:0045618positive regulation of keratinocyte differentiation3.08e-021.00e+005.0001110
GO:0010225response to UV-C3.08e-021.00e+005.0001110
GO:0042535positive regulation of tumor necrosis factor biosynthetic process3.08e-021.00e+005.0001110
GO:0031274positive regulation of pseudopodium assembly3.08e-021.00e+005.0001210
GO:0006996organelle organization3.08e-021.00e+005.0001110
GO:0001675acrosome assembly3.08e-021.00e+005.0001110
GO:0060047heart contraction3.08e-021.00e+005.0001110
GO:0000956nuclear-transcribed mRNA catabolic process3.08e-021.00e+005.0001110
GO:0008284positive regulation of cell proliferation3.38e-021.00e+001.70747392
GO:0045502dynein binding3.39e-021.00e+004.8631111
GO:0045176apical protein localization3.39e-021.00e+004.8631111
GO:0042551neuron maturation3.39e-021.00e+004.8631111
GO:0045651positive regulation of macrophage differentiation3.39e-021.00e+004.8631111
GO:0045120pronucleus3.39e-021.00e+004.8631111
GO:2000573positive regulation of DNA biosynthetic process3.39e-021.00e+004.8631211
GO:0051272positive regulation of cellular component movement3.39e-021.00e+004.8631111
GO:0035518histone H2A monoubiquitination3.39e-021.00e+004.8631211
GO:0021819layer formation in cerebral cortex3.39e-021.00e+004.8631111
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.49e-021.00e+002.7672794
GO:0035335peptidyl-tyrosine dephosphorylation3.49e-021.00e+002.7672294
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.62e-021.00e+001.44259589
GO:0007051spindle organization3.69e-021.00e+004.7371112
GO:0051146striated muscle cell differentiation3.69e-021.00e+004.7371212
GO:0032041NAD-dependent histone deacetylase activity (H3-K14 specific)3.69e-021.00e+004.7371112
GO:0046970NAD-dependent histone deacetylase activity (H4-K16 specific)3.69e-021.00e+004.7371112
GO:0048255mRNA stabilization3.69e-021.00e+004.7371112
GO:0030140trans-Golgi network transport vesicle3.69e-021.00e+004.7371112
GO:0047496vesicle transport along microtubule3.69e-021.00e+004.7371112
GO:0097372NAD-dependent histone deacetylase activity (H3-K18 specific)3.69e-021.00e+004.7371112
GO:0016568chromatin modification3.83e-021.00e+002.6932299
GO:0003713transcription coactivator activity3.86e-021.00e+002.00636239
GO:0043488regulation of mRNA stability3.99e-021.00e+004.6221113
GO:0046969NAD-dependent histone deacetylase activity (H3-K9 specific)3.99e-021.00e+004.6221113
GO:0001833inner cell mass cell proliferation3.99e-021.00e+004.6221113
GO:0031929TOR signaling3.99e-021.00e+004.6221113
GO:0061647histone H3-K9 modification3.99e-021.00e+004.6221113
GO:0005662DNA replication factor A complex3.99e-021.00e+004.6221113
GO:0071398cellular response to fatty acid3.99e-021.00e+004.6221213
GO:1900087positive regulation of G1/S transition of mitotic cell cycle3.99e-021.00e+004.6221113
GO:0007062sister chromatid cohesion3.99e-021.00e+004.6221113
GO:0030234enzyme regulator activity3.99e-021.00e+004.6221213
GO:0035371microtubule plus-end4.29e-021.00e+004.5151114
GO:0031333negative regulation of protein complex assembly4.29e-021.00e+004.5151114
GO:0070848response to growth factor4.29e-021.00e+004.5151114
GO:0015671oxygen transport4.29e-021.00e+004.5151114
GO:0006595polyamine metabolic process4.29e-021.00e+004.5151114
GO:0051298centrosome duplication4.29e-021.00e+004.5151114
GO:0030518intracellular steroid hormone receptor signaling pathway4.29e-021.00e+004.5151114
GO:0071480cellular response to gamma radiation4.29e-021.00e+004.5151114
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator4.29e-021.00e+004.5151114
GO:0031996thioesterase binding4.29e-021.00e+004.5151114
GO:0006165nucleoside diphosphate phosphorylation4.29e-021.00e+004.5151114
GO:0032465regulation of cytokinesis4.29e-021.00e+004.5151114
GO:0042809vitamin D receptor binding4.59e-021.00e+004.4151115
GO:0030131clathrin adaptor complex4.59e-021.00e+004.4151115
GO:0030225macrophage differentiation4.59e-021.00e+004.4151115
GO:0016514SWI/SNF complex4.59e-021.00e+004.4151115
GO:0045445myoblast differentiation4.59e-021.00e+004.4151115
GO:0004550nucleoside diphosphate kinase activity4.59e-021.00e+004.4151115
GO:0048821erythrocyte development4.59e-021.00e+004.4151215
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process4.59e-021.00e+004.4151115
GO:0042307positive regulation of protein import into nucleus4.59e-021.00e+004.4151215
GO:0031369translation initiation factor binding4.59e-021.00e+004.4151215
GO:0008585female gonad development4.59e-021.00e+004.4151115
GO:0051233spindle midzone4.59e-021.00e+004.4151215
GO:0048854brain morphogenesis4.59e-021.00e+004.4151115
GO:0007405neuroblast proliferation4.89e-021.00e+004.3221116
GO:0004407histone deacetylase activity4.89e-021.00e+004.3221116
GO:0060334regulation of interferon-gamma-mediated signaling pathway4.89e-021.00e+004.3221116
GO:0019226transmission of nerve impulse4.89e-021.00e+004.3221116
GO:0000132establishment of mitotic spindle orientation4.89e-021.00e+004.3221216
GO:0051276chromosome organization4.89e-021.00e+004.3221116
GO:0000209protein polyubiquitination5.10e-021.00e+002.46427116
GO:0005635nuclear envelope5.10e-021.00e+002.46422116
GO:0002548monocyte chemotaxis5.18e-021.00e+004.2351117
GO:0070933histone H4 deacetylation5.18e-021.00e+004.2351117
GO:0075733intracellular transport of virus5.18e-021.00e+004.2351317
GO:0043274phospholipase binding5.18e-021.00e+004.2351117
GO:0007141male meiosis I5.18e-021.00e+004.2351117
GO:0009966regulation of signal transduction5.18e-021.00e+004.2351117
GO:0030742GTP-dependent protein binding5.18e-021.00e+004.2351117
GO:0001556oocyte maturation5.18e-021.00e+004.2351117
GO:0008631intrinsic apoptotic signaling pathway in response to oxidative stress5.48e-021.00e+004.1521118
GO:0045773positive regulation of axon extension5.48e-021.00e+004.1521118
GO:0015949nucleobase-containing small molecule interconversion5.48e-021.00e+004.1521118
GO:0030100regulation of endocytosis5.48e-021.00e+004.1521118
GO:0010507negative regulation of autophagy5.48e-021.00e+004.1521118
GO:0090316positive regulation of intracellular protein transport5.48e-021.00e+004.1521118
GO:0006351transcription, DNA-templated5.50e-021.00e+000.8629171585
GO:0006259DNA metabolic process5.78e-021.00e+004.0741119
GO:0007088regulation of mitosis5.78e-021.00e+004.0741119
GO:0010165response to X-ray5.78e-021.00e+004.0741119
GO:0017134fibroblast growth factor binding5.78e-021.00e+004.0741219
GO:0035145exon-exon junction complex5.78e-021.00e+004.0741119
GO:0007050cell cycle arrest5.90e-021.00e+002.34522126
GO:2000134negative regulation of G1/S transition of mitotic cell cycle6.07e-021.00e+004.0001120
GO:0030036actin cytoskeleton organization6.15e-021.00e+002.31123129
GO:0046983protein dimerization activity6.32e-021.00e+002.28923131
GO:0007369gastrulation6.36e-021.00e+003.9301121
GO:0042474middle ear morphogenesis6.36e-021.00e+003.9301121
GO:0005689U12-type spliceosomal complex6.36e-021.00e+003.9301221
GO:0070932histone H3 deacetylation6.36e-021.00e+003.9301121
GO:0046847filopodium assembly6.36e-021.00e+003.9301121
GO:0009306protein secretion6.36e-021.00e+003.9301221
GO:0009615response to virus6.40e-021.00e+002.27824132
GO:0033574response to testosterone6.66e-021.00e+003.8631122
GO:0031435mitogen-activated protein kinase kinase kinase binding6.66e-021.00e+003.8631122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle6.66e-021.00e+003.8631122
GO:0007052mitotic spindle organization6.66e-021.00e+003.8631122
GO:0000086G2/M transition of mitotic cell cycle6.83e-021.00e+002.22426137
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.95e-021.00e+003.7981123
GO:0071944cell periphery6.95e-021.00e+003.7981123
GO:0002040sprouting angiogenesis6.95e-021.00e+003.7981123
GO:0045879negative regulation of smoothened signaling pathway6.95e-021.00e+003.7981123
GO:0051017actin filament bundle assembly6.95e-021.00e+003.7981123
GO:0001892embryonic placenta development6.95e-021.00e+003.7981123
GO:0051297centrosome organization6.95e-021.00e+003.7981223
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathway6.95e-021.00e+003.7981123
GO:0005761mitochondrial ribosome7.24e-021.00e+003.7371124
GO:0007163establishment or maintenance of cell polarity7.24e-021.00e+003.7371224
GO:0046329negative regulation of JNK cascade7.24e-021.00e+003.7371124
GO:0048147negative regulation of fibroblast proliferation7.24e-021.00e+003.7371124
GO:0006611protein export from nucleus7.53e-021.00e+003.6781125
GO:0046627negative regulation of insulin receptor signaling pathway7.53e-021.00e+003.6781125
GO:0060338regulation of type I interferon-mediated signaling pathway7.53e-021.00e+003.6781125
GO:0007569cell aging7.53e-021.00e+003.6781125
GO:0046966thyroid hormone receptor binding7.82e-021.00e+003.6221126
GO:0045859regulation of protein kinase activity7.82e-021.00e+003.6221126
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity7.82e-021.00e+003.6221226
GO:0051149positive regulation of muscle cell differentiation8.11e-021.00e+003.5671227
GO:0032720negative regulation of tumor necrosis factor production8.11e-021.00e+003.5671127
GO:0005083small GTPase regulator activity8.11e-021.00e+003.5671127
GO:0031424keratinization8.11e-021.00e+003.5671127
GO:0048565digestive tract development8.11e-021.00e+003.5671127
GO:0031069hair follicle morphogenesis8.11e-021.00e+003.5671127
GO:0032467positive regulation of cytokinesis8.40e-021.00e+003.5151128
GO:0043967histone H4 acetylation8.40e-021.00e+003.5151228
GO:0005875microtubule associated complex8.40e-021.00e+003.5151128
GO:0007017microtubule-based process8.40e-021.00e+003.5151228
GO:0000118histone deacetylase complex8.40e-021.00e+003.5151128
GO:0042626ATPase activity, coupled to transmembrane movement of substances8.40e-021.00e+003.5151128
GO:0003682chromatin binding8.63e-021.00e+001.52334334
GO:0000381regulation of alternative mRNA splicing, via spliceosome8.68e-021.00e+003.4641129
GO:0031252cell leading edge8.68e-021.00e+003.4641329
GO:0003730mRNA 3'-UTR binding8.68e-021.00e+003.4641129
GO:0034605cellular response to heat8.68e-021.00e+003.4641129
GO:0072686mitotic spindle8.68e-021.00e+003.4641129
GO:0006974cellular response to DNA damage stimulus8.73e-021.00e+002.01823158
GO:0005198structural molecule activity8.83e-021.00e+002.00925159
GO:0010977negative regulation of neuron projection development8.97e-021.00e+003.4151230
GO:0001618virus receptor activity8.97e-021.00e+003.4151130
GO:0051262protein tetramerization8.97e-021.00e+003.4151130
GO:0007346regulation of mitotic cell cycle8.97e-021.00e+003.4151330
GO:0046875ephrin receptor binding8.97e-021.00e+003.4151230
GO:0070491repressing transcription factor binding8.97e-021.00e+003.4151130
GO:0031647regulation of protein stability8.97e-021.00e+003.4151130
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator8.97e-021.00e+003.4151130
GO:0040018positive regulation of multicellular organism growth8.97e-021.00e+003.4151130
GO:0010494cytoplasmic stress granule8.97e-021.00e+003.4151230
GO:0045171intercellular bridge9.25e-021.00e+003.3681231
GO:0070373negative regulation of ERK1 and ERK2 cascade9.25e-021.00e+003.3681131
GO:0000398mRNA splicing, via spliceosome9.40e-021.00e+001.95622165
GO:0034644cellular response to UV9.54e-021.00e+003.3221132
GO:0033572transferrin transport9.54e-021.00e+003.3221132
GO:0070888E-box binding9.54e-021.00e+003.3221132
GO:0015992proton transport9.54e-021.00e+003.3221132
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding9.69e-021.00e+001.93024168
GO:0002053positive regulation of mesenchymal cell proliferation9.82e-021.00e+003.2781133
GO:0005158insulin receptor binding9.82e-021.00e+003.2781233
GO:0030971receptor tyrosine kinase binding9.82e-021.00e+003.2781133
GO:0033077T cell differentiation in thymus9.82e-021.00e+003.2781133
GO:0001104RNA polymerase II transcription cofactor activity9.82e-021.00e+003.2781233
GO:0007611learning or memory1.01e-011.00e+003.2351234
GO:0001890placenta development1.01e-011.00e+003.2351134
GO:0042692muscle cell differentiation1.01e-011.00e+003.2351234
GO:0051701interaction with host1.01e-011.00e+003.2351134
GO:0071333cellular response to glucose stimulus1.04e-011.00e+003.1931235
GO:0016592mediator complex1.04e-011.00e+003.1931235
GO:0031965nuclear membrane1.05e-011.00e+001.86322176
GO:0007049cell cycle1.06e-011.00e+001.85424177
GO:0034332adherens junction organization1.07e-011.00e+003.1521436
GO:0051402neuron apoptotic process1.07e-011.00e+003.1521136
GO:0000228nuclear chromosome1.07e-011.00e+003.1521236
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.07e-011.00e+003.1521336
GO:0045944positive regulation of transcription from RNA polymerase II promoter1.08e-011.00e+000.980511811
GO:0001102RNA polymerase II activating transcription factor binding1.09e-011.00e+003.1131137
GO:0031625ubiquitin protein ligase binding1.09e-011.00e+001.83024180
GO:0097191extrinsic apoptotic signaling pathway1.12e-011.00e+003.0741338
GO:0045740positive regulation of DNA replication1.12e-011.00e+003.0741138
GO:0090382phagosome maturation1.12e-011.00e+003.0741138
GO:0006367transcription initiation from RNA polymerase II promoter1.13e-011.00e+001.79825184
GO:0051781positive regulation of cell division1.15e-011.00e+003.0371139
GO:0032092positive regulation of protein binding1.15e-011.00e+003.0371139
GO:0050885neuromuscular process controlling balance1.21e-011.00e+002.9641141
GO:0021987cerebral cortex development1.23e-011.00e+002.9301142
GO:0009898cytoplasmic side of plasma membrane1.23e-011.00e+002.9301142
GO:0031532actin cytoskeleton reorganization1.23e-011.00e+002.9301242
GO:0035914skeletal muscle cell differentiation1.23e-011.00e+002.9301142
GO:0003677DNA binding1.26e-011.00e+000.7307141351
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity1.26e-011.00e+002.8961143
GO:0001658branching involved in ureteric bud morphogenesis1.26e-011.00e+002.8961143
GO:0004402histone acetyltransferase activity1.26e-011.00e+002.8961143
GO:0006355regulation of transcription, DNA-templated1.28e-011.00e+000.7986101104
GO:0007286spermatid development1.29e-011.00e+002.8631144
GO:0003712transcription cofactor activity1.29e-011.00e+002.8631144
GO:0005871kinesin complex1.29e-011.00e+002.8631144
GO:0048146positive regulation of fibroblast proliferation1.29e-011.00e+002.8631144
GO:0034613cellular protein localization1.29e-011.00e+002.8631244
GO:0043966histone H3 acetylation1.32e-011.00e+002.8301145
GO:0009411response to UV1.32e-011.00e+002.8301245
GO:0003924GTPase activity1.32e-011.00e+001.65726203
GO:0051591response to cAMP1.32e-011.00e+002.8301145
GO:0044297cell body1.34e-011.00e+002.7981146
GO:0043525positive regulation of neuron apoptotic process1.34e-011.00e+002.7981246
GO:0045727positive regulation of translation1.34e-011.00e+002.7981146
GO:0021762substantia nigra development1.34e-011.00e+002.7981246
GO:0001047core promoter binding1.34e-011.00e+002.7981146
GO:0000139Golgi membrane1.35e-011.00e+001.23537408
GO:0001701in utero embryonic development1.40e-011.00e+001.60822210
GO:0019003GDP binding1.40e-011.00e+002.7371148
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage1.42e-011.00e+002.7071249
GO:0022625cytosolic large ribosomal subunit1.42e-011.00e+002.7071149
GO:0003743translation initiation factor activity1.42e-011.00e+002.7071549
GO:0007030Golgi organization1.45e-011.00e+002.6781350
GO:0000910cytokinesis1.48e-011.00e+002.6501251
GO:0003684damaged DNA binding1.48e-011.00e+002.6501251
GO:0045732positive regulation of protein catabolic process1.48e-011.00e+002.6501151
GO:0004197cysteine-type endopeptidase activity1.50e-011.00e+002.6221252
GO:0016042lipid catabolic process1.50e-011.00e+002.6221252
GO:0006184GTP catabolic process1.51e-011.00e+001.54126220
GO:0006952defense response1.53e-011.00e+002.5941153
GO:0030175filopodium1.53e-011.00e+002.5941253
GO:0019900kinase binding1.56e-011.00e+002.5671354
GO:0050680negative regulation of epithelial cell proliferation1.56e-011.00e+002.5671154
GO:0097193intrinsic apoptotic signaling pathway1.58e-011.00e+002.5411255
GO:0000226microtubule cytoskeleton organization1.58e-011.00e+002.5411155
GO:0046330positive regulation of JNK cascade1.58e-011.00e+002.5411155
GO:0006888ER to Golgi vesicle-mediated transport1.58e-011.00e+002.5411155
GO:0008380RNA splicing1.64e-011.00e+001.46425232
GO:0000724double-strand break repair via homologous recombination1.64e-011.00e+002.4891257
GO:0030097hemopoiesis1.66e-011.00e+002.4641158
GO:0005643nuclear pore1.69e-011.00e+002.4391159
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.69e-011.00e+002.4391159
GO:0050728negative regulation of inflammatory response1.71e-011.00e+002.4151260
GO:0010976positive regulation of neuron projection development1.71e-011.00e+002.4151260
GO:0030425dendrite1.73e-011.00e+001.41523240
GO:0033138positive regulation of peptidyl-serine phosphorylation1.74e-011.00e+002.3911161
GO:0006302double-strand break repair1.77e-011.00e+002.3681262
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.77e-011.00e+002.3681162
GO:0060337type I interferon signaling pathway1.79e-011.00e+002.3451163
GO:0000776kinetochore1.79e-011.00e+002.3451363
GO:0032088negative regulation of NF-kappaB transcription factor activity1.82e-011.00e+002.3221164
GO:0007059chromosome segregation1.82e-011.00e+002.3221364
GO:0060333interferon-gamma-mediated signaling pathway1.82e-011.00e+002.3221164
GO:0006469negative regulation of protein kinase activity1.84e-011.00e+002.3001165
GO:0071260cellular response to mechanical stimulus1.87e-011.00e+002.2781366
GO:0043202lysosomal lumen1.87e-011.00e+002.2781166
GO:0043025neuronal cell body1.88e-011.00e+001.33325254
GO:0031295T cell costimulation1.90e-011.00e+002.2561367
GO:0018105peptidyl-serine phosphorylation1.95e-011.00e+002.2131569
GO:0006289nucleotide-excision repair1.95e-011.00e+002.2131169
GO:0050790regulation of catalytic activity1.95e-011.00e+002.2131169
GO:0035264multicellular organism growth1.97e-011.00e+002.1931170
GO:0001503ossification2.00e-011.00e+002.1721271
GO:0010468regulation of gene expression2.02e-011.00e+002.1521172
GO:0000165MAPK cascade2.02e-011.00e+002.1521272
GO:0055086nucleobase-containing small molecule metabolic process2.05e-011.00e+002.1321273
GO:0002020protease binding2.07e-011.00e+002.1131174
GO:0007265Ras protein signal transduction2.10e-011.00e+002.0931375
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding2.10e-011.00e+002.0931175
GO:0031175neuron projection development2.10e-011.00e+002.0931275
GO:0043065positive regulation of apoptotic process2.11e-011.00e+001.22426274
GO:0007283spermatogenesis2.13e-011.00e+001.21322276
GO:0044325ion channel binding2.15e-011.00e+002.0551377
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.15e-011.00e+002.0551477
GO:0008584male gonad development2.15e-011.00e+002.0551177
GO:0007229integrin-mediated signaling pathway2.17e-011.00e+002.0371278
GO:0001822kidney development2.20e-011.00e+002.0181279
GO:0071013catalytic step 2 spliceosome2.20e-011.00e+002.0181179
GO:0004725protein tyrosine phosphatase activity2.22e-011.00e+002.0001180
GO:0005814centriole2.22e-011.00e+002.0001180
GO:0030968endoplasmic reticulum unfolded protein response2.24e-011.00e+001.9821181
GO:0045177apical part of cell2.27e-011.00e+001.9641182
GO:0001726ruffle2.27e-011.00e+001.9641182
GO:0007264small GTPase mediated signal transduction2.29e-011.00e+001.14227290
GO:0005929cilium2.32e-011.00e+001.9301284
GO:0005179hormone activity2.32e-011.00e+001.9301184
GO:0042593glucose homeostasis2.44e-011.00e+001.8461189
GO:0042384cilium assembly2.46e-011.00e+001.8301290
GO:0000922spindle pole2.48e-011.00e+001.8141591
GO:0003690double-stranded DNA binding2.48e-011.00e+001.8141291
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.51e-011.00e+001.7981392
GO:0016605PML body2.51e-011.00e+001.7981292
GO:0042470melanosome2.51e-011.00e+001.7981292
GO:0001649osteoblast differentiation2.58e-011.00e+001.7521395
GO:0001764neuron migration2.60e-011.00e+001.7371296
GO:0030426growth cone2.62e-011.00e+001.7221397
GO:0006112energy reserve metabolic process2.67e-011.00e+001.6931299
GO:0005525GTP binding2.73e-011.00e+000.96426328
GO:0004888transmembrane signaling receptor activity2.76e-011.00e+001.63611103
GO:0043231intracellular membrane-bounded organelle2.78e-011.00e+000.94723332
GO:0014069postsynaptic density2.83e-011.00e+001.59413106
GO:0030496midbody2.90e-011.00e+001.55414109
GO:0005938cell cortex2.90e-011.00e+001.55411109
GO:0007275multicellular organismal development2.92e-011.00e+000.89622344
GO:0031410cytoplasmic vesicle2.92e-011.00e+001.54111110
GO:0005815microtubule organizing center2.92e-011.00e+001.54114110
GO:0007605sensory perception of sound2.94e-011.00e+001.52811111
GO:0015630microtubule cytoskeleton2.97e-011.00e+001.51514112
GO:0005819spindle3.01e-011.00e+001.48914114
GO:0042803protein homodimerization activity3.03e-011.00e+000.63834617
GO:0032496response to lipopolysaccharide3.18e-011.00e+001.39111122
GO:0008285negative regulation of cell proliferation3.19e-011.00e+000.80223367
GO:0001501skeletal system development3.21e-011.00e+001.38011123
GO:0051056regulation of small GTPase mediated signal transduction3.21e-011.00e+001.38013123
GO:0007219Notch signaling pathway3.25e-011.00e+001.35614125
GO:0006511ubiquitin-dependent protein catabolic process3.29e-011.00e+001.33313127
GO:0008201heparin binding3.29e-011.00e+001.33311127
GO:0005794Golgi apparatus3.32e-011.00e+000.56338650
GO:0030027lamellipodium3.35e-011.00e+001.30013130
GO:0007179transforming growth factor beta receptor signaling pathway3.35e-011.00e+001.30014130
GO:0031982vesicle3.44e-011.00e+001.25612134
GO:0005911cell-cell junction3.60e-011.00e+001.17212142
GO:0010628positive regulation of gene expression3.74e-011.00e+001.10314149
GO:0008017microtubule binding3.76e-011.00e+001.09312150
GO:0051260protein homooligomerization3.76e-011.00e+001.09312150
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.78e-011.00e+001.08412151
GO:0044281small molecule metabolic process3.81e-011.00e+000.3055161295
GO:0005769early endosome3.92e-011.00e+001.01811158
GO:0043005neuron projection3.97e-011.00e+000.99116161
GO:0006397mRNA processing4.12e-011.00e+000.92113169
GO:0007420brain development4.18e-011.00e+000.89613172
GO:0030424axon4.18e-011.00e+000.89614172
GO:0016607nuclear speck4.23e-011.00e+000.87112175
GO:0045211postsynaptic membrane4.27e-011.00e+000.85413177
GO:0007596blood coagulation4.28e-011.00e+000.46425464
GO:0006468protein phosphorylation4.31e-011.00e+000.45526467
GO:0019904protein domain specific binding4.34e-011.00e+000.82213181
GO:0005764lysosome4.36e-011.00e+000.81412182
GO:0032403protein complex binding4.41e-011.00e+000.79112185
GO:0007173epidermal growth factor receptor signaling pathway4.52e-011.00e+000.74515191
GO:0042802identical protein binding4.57e-011.00e+000.38224491
GO:0004872receptor activity4.66e-011.00e+000.68511199
GO:0030168platelet activation4.76e-011.00e+000.64314205
GO:0046872metal ion binding4.88e-011.00e+000.1275141465
GO:0005765lysosomal membrane4.97e-011.00e+000.55412218
GO:0019221cytokine-mediated signaling pathway5.16e-011.00e+000.47715230
GO:0006915apoptotic process5.37e-011.00e+000.16529571
GO:0007399nervous system development5.38e-011.00e+000.38511245
GO:0006281DNA repair5.65e-011.00e+000.27815264
GO:0005783endoplasmic reticulum5.73e-011.00e+000.06926610
GO:0000166nucleotide binding5.76e-011.00e+000.23512272
GO:0019899enzyme binding5.97e-011.00e+000.15215288
GO:0042493response to drug5.97e-011.00e+000.15212288
GO:0005856cytoskeleton6.26e-011.00e+000.04116311
GO:0004674protein serine/threonine kinase activity6.27e-011.00e+000.03716312
GO:0035556intracellular signal transduction6.33e-011.00e+000.01415317
GO:0005575cellular_component6.39e-011.00e+00-0.00912322
GO:0030154cell differentiation6.42e-011.00e+00-0.02213325
GO:0005739mitochondrion6.43e-011.00e+00-0.1243101046
GO:0007411axon guidance6.44e-011.00e+00-0.03113327
GO:0008270zinc ion binding6.57e-011.00e+00-0.152371067
GO:0007268synaptic transmission6.73e-011.00e+00-0.14211353
GO:0030054cell junction6.76e-011.00e+00-0.15414356
GO:0015031protein transport6.77e-011.00e+00-0.15814357
GO:0007155cell adhesion7.04e-011.00e+00-0.26313384
GO:0006508proteolysis7.27e-011.00e+00-0.35712410
GO:0045892negative regulation of transcription, DNA-templated7.39e-011.00e+00-0.40612424
GO:0006366transcription from RNA polymerase II promoter7.40e-011.00e+00-0.40913425
GO:0008150biological_process7.67e-011.00e+00-0.52013459
GO:0007165signal transduction8.05e-011.00e+00-0.57027950
GO:0055085transmembrane transport8.05e-011.00e+00-0.68413514
GO:0005886plasma membrane8.06e-011.00e+00-0.3397242834
GO:0005524ATP binding8.07e-011.00e+00-0.4963191354
GO:0003674molecular_function8.11e-011.00e+00-0.71111524
GO:0045087innate immune response8.60e-011.00e+00-0.945111616
GO:0005789endoplasmic reticulum membrane8.69e-011.00e+00-0.99113636
GO:0005615extracellular space9.62e-011.00e+00-1.658131010
GO:0005576extracellular region9.66e-011.00e+00-1.713141049
GO:0016021integral component of membrane1.00e+001.00e+00-2.956142483