reg-snw-6169

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.851	3.99e-26	2.70e-04	4.60e-04

tai-screen-luciferase-reg-snw-6169 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
TLK2	11011	8	-4.011	5.672	14	-	-	-
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
YBX1	4904	6	-3.033	5.516	120	TF	-	-
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes
[ RPL38 ]	6169	1	-1.992	4.851	4	-	Yes	-
CDC5L	988	15	-3.419	5.672	155	TF	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC5L	988	RPL38	6169	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	YBX1	4904	pd	<>	reg.ITFP.txt: no annot
YBX1	4904	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot

Related GO terms (107)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006412	translation	3.12e-04	1.00e+00	4.363	3	13	178
GO:0003723	RNA binding	8.15e-04	1.00e+00	3.890	3	6	247
GO:0048318	axial mesoderm development	8.19e-04	1.00e+00	10.253	1	1	1
GO:0071987	WD40-repeat domain binding	8.19e-04	1.00e+00	10.253	1	1	1
GO:0033291	eukaryotic 80S initiation complex	8.19e-04	1.00e+00	10.253	1	1	1
GO:0034463	90S preribosome assembly	8.19e-04	1.00e+00	10.253	1	1	1
GO:0002176	male germ cell proliferation	1.64e-03	1.00e+00	9.253	1	1	2
GO:0001672	regulation of chromatin assembly or disassembly	1.64e-03	1.00e+00	9.253	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.64e-03	1.00e+00	9.253	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.64e-03	1.00e+00	9.253	1	1	2
GO:0044822	poly(A) RNA binding	2.38e-03	1.00e+00	2.611	4	25	799
GO:0005850	eukaryotic translation initiation factor 2 complex	2.46e-03	1.00e+00	8.668	1	1	3
GO:0051154	negative regulation of striated muscle cell differentiation	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006413	translational initiation	2.74e-03	1.00e+00	4.624	2	12	99
GO:0050658	RNA transport	3.27e-03	1.00e+00	8.253	1	1	4
GO:0030157	pancreatic juice secretion	3.27e-03	1.00e+00	8.253	1	1	4
GO:0003735	structural constituent of ribosome	3.31e-03	1.00e+00	4.485	2	8	109
GO:0000974	Prp19 complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000930	gamma-tubulin complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000398	mRNA splicing, via spliceosome	4.53e-03	1.00e+00	4.253	2	2	128
GO:0070937	CRD-mediated mRNA stability complex	4.91e-03	1.00e+00	7.668	1	1	6
GO:0030126	COPI vesicle coat	5.72e-03	1.00e+00	7.446	1	1	7
GO:0001701	in utero embryonic development	6.50e-03	1.00e+00	3.987	2	2	154
GO:0005662	DNA replication factor A complex	6.54e-03	1.00e+00	7.253	1	1	8
GO:0010467	gene expression	7.44e-03	1.00e+00	2.775	3	17	535
GO:0071480	cellular response to gamma radiation	8.17e-03	1.00e+00	6.931	1	1	10
GO:0010507	negative regulation of autophagy	8.17e-03	1.00e+00	6.931	1	1	10
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	8.17e-03	1.00e+00	6.931	1	1	10
GO:0007051	spindle organization	8.17e-03	1.00e+00	6.931	1	1	10
GO:0015935	small ribosomal subunit	9.79e-03	1.00e+00	6.668	1	4	12
GO:0051297	centrosome organization	9.79e-03	1.00e+00	6.668	1	1	12
GO:0048205	COPI coating of Golgi vesicle	9.79e-03	1.00e+00	6.668	1	1	12
GO:0035371	microtubule plus-end	1.06e-02	1.00e+00	6.553	1	1	13
GO:0042474	middle ear morphogenesis	1.14e-02	1.00e+00	6.446	1	1	14
GO:0008135	translation factor activity, nucleic acid binding	1.22e-02	1.00e+00	6.347	1	4	15
GO:0005689	U12-type spliceosomal complex	1.38e-02	1.00e+00	6.166	1	2	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.38e-02	1.00e+00	6.166	1	1	17
GO:0005761	mitochondrial ribosome	1.63e-02	1.00e+00	5.931	1	1	20
GO:0051781	positive regulation of cell division	1.79e-02	1.00e+00	5.794	1	1	22
GO:0010494	cytoplasmic stress granule	2.11e-02	1.00e+00	5.553	1	2	26
GO:0022625	cytosolic large ribosomal subunit	2.91e-02	1.00e+00	5.083	1	1	36
GO:0003743	translation initiation factor activity	2.99e-02	1.00e+00	5.044	1	5	37
GO:0044267	cellular protein metabolic process	3.14e-02	1.00e+00	2.794	2	13	352
GO:0006417	regulation of translation	3.15e-02	1.00e+00	4.968	1	3	39
GO:0005882	intermediate filament	3.23e-02	1.00e+00	4.931	1	2	40
GO:0007059	chromosome segregation	4.03e-02	1.00e+00	4.610	1	1	50
GO:0018105	peptidyl-serine phosphorylation	4.10e-02	1.00e+00	4.581	1	2	51
GO:0005829	cytosol	4.19e-02	1.00e+00	1.450	4	33	1787
GO:0001503	ossification	4.50e-02	1.00e+00	4.446	1	1	56
GO:0008584	male gonad development	4.58e-02	1.00e+00	4.421	1	1	57
GO:0003697	single-stranded DNA binding	4.58e-02	1.00e+00	4.421	1	3	57
GO:0005179	hormone activity	4.81e-02	1.00e+00	4.347	1	1	60
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	1	61
GO:0019083	viral transcription	4.89e-02	1.00e+00	4.323	1	7	61
GO:0006415	translational termination	5.05e-02	1.00e+00	4.276	1	7	63
GO:0000922	spindle pole	5.44e-02	1.00e+00	4.166	1	3	68
GO:0016568	chromatin modification	5.44e-02	1.00e+00	4.166	1	2	68
GO:0006414	translational elongation	5.52e-02	1.00e+00	4.145	1	7	69
GO:0007605	sensory perception of sound	5.67e-02	1.00e+00	4.104	1	1	71
GO:0015630	microtubule cytoskeleton	5.98e-02	1.00e+00	4.025	1	2	75
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	6.14e-02	1.00e+00	3.987	1	7	77
GO:0019058	viral life cycle	6.22e-02	1.00e+00	3.968	1	8	78
GO:0005515	protein binding	6.50e-02	1.00e+00	0.829	6	50	4124
GO:0030529	ribonucleoprotein complex	6.53e-02	1.00e+00	3.896	1	3	82
GO:0001501	skeletal system development	6.53e-02	1.00e+00	3.896	1	1	82
GO:0016020	membrane	6.54e-02	1.00e+00	1.601	3	25	1207
GO:0003690	double-stranded DNA binding	6.60e-02	1.00e+00	3.878	1	1	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	7	84
GO:0006886	intracellular protein transport	7.07e-02	1.00e+00	3.778	1	1	89
GO:0061024	membrane organization	7.07e-02	1.00e+00	3.778	1	3	89
GO:0000086	G2/M transition of mitotic cell cycle	7.68e-02	1.00e+00	3.653	1	3	97
GO:0005198	structural molecule activity	7.98e-02	1.00e+00	3.595	1	1	101
GO:0007049	cell cycle	9.05e-02	1.00e+00	3.408	1	2	115
GO:0006974	cellular response to DNA damage stimulus	9.50e-02	1.00e+00	3.335	1	2	121
GO:0016607	nuclear speck	9.57e-02	1.00e+00	3.323	1	2	122
GO:0031965	nuclear membrane	1.02e-01	1.00e+00	3.231	1	2	130
GO:0006355	regulation of transcription, DNA-templated	1.12e-01	1.00e+00	1.772	2	9	715
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	5	165
GO:0008380	RNA splicing	1.27e-01	1.00e+00	2.887	1	4	165
GO:0016071	mRNA metabolic process	1.31e-01	1.00e+00	2.844	1	11	170
GO:0016070	RNA metabolic process	1.44e-01	1.00e+00	2.699	1	11	188
GO:0004674	protein serine/threonine kinase activity	1.50e-01	1.00e+00	2.631	1	3	197
GO:0035556	intracellular signal transduction	1.52e-01	1.00e+00	2.617	1	3	199
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	8	210
GO:0043231	intracellular membrane-bounded organelle	1.65e-01	1.00e+00	2.485	1	1	218
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	6	217
GO:0003677	DNA binding	1.78e-01	1.00e+00	1.366	2	12	947
GO:0003682	chromatin binding	1.89e-01	1.00e+00	2.276	1	3	252
GO:0005925	focal adhesion	2.09e-01	1.00e+00	2.114	1	12	282
GO:0006468	protein phosphorylation	2.22e-01	1.00e+00	2.020	1	3	301
GO:0000278	mitotic cell cycle	2.30e-01	1.00e+00	1.959	1	9	314
GO:0006366	transcription from RNA polymerase II promoter	2.48e-01	1.00e+00	1.840	1	2	341
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	7	344
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	21	1217
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	6	456
GO:0005737	cytoplasm	3.71e-01	1.00e+00	0.476	3	39	2633
GO:0003700	sequence-specific DNA binding transcription factor activity	3.88e-01	1.00e+00	1.069	1	9	582
GO:0070062	extracellular vesicular exosome	4.00e-01	1.00e+00	0.573	2	28	1641
GO:0005615	extracellular space	4.24e-01	1.00e+00	0.907	1	2	651
GO:0005654	nucleoplasm	5.29e-01	1.00e+00	0.479	1	16	876
GO:0005634	nucleus	5.30e-01	1.00e+00	0.174	3	40	3246
GO:0005524	ATP binding	5.35e-01	1.00e+00	0.453	1	10	892
GO:0046872	metal ion binding	5.53e-01	1.00e+00	0.386	1	10	934
GO:0006351	transcription, DNA-templated	6.07e-01	1.00e+00	0.182	1	15	1076

Tai-Luciferase

reg-snw-6169

Statistics

Genes (8)

Interactions (7)

Related GO terms (107)