int-snw-51382

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	7.286	3.65e-186	4.21e-10	1.27e-04

tai-screen-luciferase-int-snw-51382 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
RPS4X	6191	18	-6.747	7.555	263	Yes	-
COPZ1	22818	32	-8.301	9.063	13	Yes	Yes
[ ATP6V1D ]	51382	8	-4.131	7.286	149	-	-
EIF2S2	8894	2	-4.320	7.286	81	Yes	-
COPA	1314	32	-9.395	9.063	170	Yes	Yes
RPS11	6205	17	-6.588	7.555	175	Yes	-
RPS6	6194	17	-5.603	8.046	208	Yes	-
RPS24	6229	21	-7.034	8.389	217	Yes	-
RPS26	6231	17	-7.478	8.046	60	Yes	-
RPS9	6203	18	-7.127	7.555	140	Yes	-
ARCN1	372	32	-8.232	9.063	118	Yes	Yes
COPB2	9276	32	-13.168	9.063	41	Yes	Yes
RPS13	6207	17	-6.589	7.555	174	Yes	-

Interactions (25)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPS9	6203	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS9	6203	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
EIF2S2	8894	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS9	6203	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
RPS4X	6191	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
RPS11	6205	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
COPA	1314	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS4X	6191	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS4X	6191	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS26	6231	pp	--	int.I2D: YeastLow
RPS6	6194	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
RPS24	6229	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo

Related GO terms (102)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0022627	cytosolic small ribosomal subunit	1.01e-15	1.46e-11	7.638	7	20	39
GO:0006413	translational initiation	4.62e-14	6.67e-10	6.082	8	21	131
GO:0019083	viral transcription	2.26e-13	3.26e-09	6.583	7	20	81
GO:0006415	translational termination	3.79e-13	5.46e-09	6.480	7	20	87
GO:0006414	translational elongation	6.12e-13	8.83e-09	6.384	7	20	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.37e-12	1.97e-08	6.223	7	20	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.64e-12	3.81e-08	6.090	7	20	114
GO:0019058	viral life cycle	2.81e-12	4.05e-08	6.078	7	23	115
GO:0006412	translation	4.45e-12	6.42e-08	5.270	8	23	230
GO:0003735	structural constituent of ribosome	9.78e-12	1.41e-07	5.825	7	22	137
GO:0005829	cytosol	1.22e-10	1.75e-06	2.531	13	61	2496
GO:0030126	COPI vesicle coat	1.96e-10	2.82e-06	8.531	4	7	12
GO:0048205	COPI coating of Golgi vesicle	2.82e-10	4.07e-06	8.415	4	8	13
GO:0016071	mRNA metabolic process	3.05e-10	4.40e-06	5.122	7	25	223
GO:0016070	RNA metabolic process	6.24e-10	9.00e-06	4.975	7	25	247
GO:0015935	small ribosomal subunit	9.38e-10	1.35e-05	8.028	4	9	17
GO:0044267	cellular protein metabolic process	1.43e-09	2.06e-05	4.227	8	23	474
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	4.97e-09	7.16e-05	7.472	4	8	25
GO:0010467	gene expression	2.15e-08	3.10e-04	3.730	8	29	669
GO:0044822	poly(A) RNA binding	3.20e-08	4.61e-04	3.241	9	32	1056
GO:0016020	membrane	9.25e-08	1.33e-03	2.722	10	41	1681
GO:0016032	viral process	1.30e-07	1.87e-03	3.862	7	33	534
GO:0005840	ribosome	1.64e-07	2.36e-03	6.258	4	8	58
GO:0019843	rRNA binding	1.65e-06	2.38e-02	6.946	3	4	27
GO:0061024	membrane organization	6.53e-06	9.42e-02	4.936	4	12	145
GO:0033119	negative regulation of RNA splicing	7.49e-06	1.08e-01	8.794	2	2	5
GO:0006886	intracellular protein transport	1.25e-05	1.81e-01	4.698	4	7	171
GO:0042274	ribosomal small subunit biogenesis	4.92e-05	7.10e-01	7.531	2	6	12
GO:0006891	intra-Golgi vesicle-mediated transport	1.01e-04	1.00e+00	7.028	2	4	17
GO:0030529	ribonucleoprotein complex	1.23e-04	1.00e+00	4.893	3	7	112
GO:0036464	cytoplasmic ribonucleoprotein granule	1.71e-04	1.00e+00	6.656	2	3	22
GO:0005844	polysome	1.88e-04	1.00e+00	6.592	2	2	23
GO:0005925	focal adhesion	2.43e-04	1.00e+00	3.600	4	19	366
GO:0033176	proton-transporting V-type ATPase complex	9.01e-04	1.00e+00	10.116	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0022605	oogenesis stage	9.01e-04	1.00e+00	10.116	1	1	1
GO:0002176	male germ cell proliferation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0003729	mRNA binding	1.85e-03	1.00e+00	4.946	2	2	72
GO:0070062	extracellular vesicular exosome	2.36e-03	1.00e+00	1.694	7	40	2400
GO:0005850	eukaryotic translation initiation factor 2 complex	2.70e-03	1.00e+00	8.531	1	1	3
GO:0006364	rRNA processing	3.13e-03	1.00e+00	4.561	2	7	94
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.50e-03	1.00e+00	7.794	1	3	5
GO:0045182	translation regulator activity	5.40e-03	1.00e+00	7.531	1	2	6
GO:0061512	protein localization to cilium	5.40e-03	1.00e+00	7.531	1	1	6
GO:0006924	activation-induced cell death of T cells	5.40e-03	1.00e+00	7.531	1	1	6
GO:0002309	T cell proliferation involved in immune response	5.40e-03	1.00e+00	7.531	1	1	6
GO:0034101	erythrocyte homeostasis	6.29e-03	1.00e+00	7.308	1	1	7
GO:0030157	pancreatic juice secretion	6.29e-03	1.00e+00	7.308	1	1	7
GO:0000028	ribosomal small subunit assembly	6.29e-03	1.00e+00	7.308	1	3	7
GO:0008286	insulin receptor signaling pathway	6.99e-03	1.00e+00	3.966	2	3	142
GO:0005198	structural molecule activity	7.77e-03	1.00e+00	3.887	2	6	150
GO:0005730	nucleolus	1.11e-02	1.00e+00	1.757	5	24	1641
GO:0031929	TOR signaling	1.17e-02	1.00e+00	6.415	1	1	13
GO:0030131	clathrin adaptor complex	1.26e-02	1.00e+00	6.308	1	2	14
GO:0031369	translation initiation factor binding	1.34e-02	1.00e+00	6.209	1	1	15
GO:0048821	erythrocyte development	1.34e-02	1.00e+00	6.209	1	1	15
GO:0007369	gastrulation	1.70e-02	1.00e+00	5.868	1	1	19
GO:0043473	pigmentation	1.79e-02	1.00e+00	5.794	1	1	20
GO:0008135	translation factor activity, nucleic acid binding	2.14e-02	1.00e+00	5.531	1	1	24
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	2.32e-02	1.00e+00	5.415	1	1	26
GO:0015992	proton transport	2.58e-02	1.00e+00	5.258	1	1	29
GO:0033572	transferrin transport	2.67e-02	1.00e+00	5.209	1	1	30
GO:0001890	placenta development	2.76e-02	1.00e+00	5.161	1	1	31
GO:0007093	mitotic cell cycle checkpoint	2.76e-02	1.00e+00	5.161	1	1	31
GO:0051701	interaction with host	2.85e-02	1.00e+00	5.116	1	1	32
GO:0033077	T cell differentiation in thymus	2.94e-02	1.00e+00	5.071	1	1	33
GO:0090382	phagosome maturation	3.20e-02	1.00e+00	4.946	1	1	36
GO:0045727	positive regulation of translation	3.90e-02	1.00e+00	4.656	1	1	44
GO:0008344	adult locomotory behavior	3.90e-02	1.00e+00	4.656	1	1	44
GO:0044297	cell body	4.07e-02	1.00e+00	4.592	1	1	46
GO:0003743	translation initiation factor activity	4.33e-02	1.00e+00	4.501	1	1	49
GO:0006879	cellular iron ion homeostasis	4.50e-02	1.00e+00	4.443	1	1	51
GO:0008284	positive regulation of cell proliferation	4.50e-02	1.00e+00	2.538	2	7	382
GO:0006417	regulation of translation	5.45e-02	1.00e+00	4.161	1	2	62
GO:0008584	male gonad development	6.56e-02	1.00e+00	3.887	1	1	75
GO:0005929	cilium	6.72e-02	1.00e+00	3.849	1	1	77
GO:0005179	hormone activity	6.89e-02	1.00e+00	3.812	1	1	79
GO:0042384	cilium assembly	7.48e-02	1.00e+00	3.689	1	1	86
GO:0042593	glucose homeostasis	7.57e-02	1.00e+00	3.673	1	1	87
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	3	92
GO:0005737	cytoplasm	9.60e-02	1.00e+00	0.821	6	43	3767
GO:0000082	G1/S transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	9	149
GO:0001701	in utero embryonic development	1.67e-01	1.00e+00	2.465	1	2	201
GO:0005765	lysosomal membrane	1.68e-01	1.00e+00	2.450	1	2	203
GO:0007067	mitotic nuclear division	1.86e-01	1.00e+00	2.289	1	5	227
GO:0030425	dendrite	1.89e-01	1.00e+00	2.270	1	2	230
GO:0000166	nucleotide binding	2.10e-01	1.00e+00	2.099	1	2	259
GO:0043065	positive regulation of apoptotic process	2.16e-01	1.00e+00	2.050	1	6	268
GO:0007275	multicellular organismal development	2.50e-01	1.00e+00	1.812	1	1	316
GO:0019901	protein kinase binding	2.51e-01	1.00e+00	1.807	1	6	317
GO:0043231	intracellular membrane-bounded organelle	2.52e-01	1.00e+00	1.803	1	5	318
GO:0005813	centrosome	2.57e-01	1.00e+00	1.767	1	5	326
GO:0003723	RNA binding	2.68e-01	1.00e+00	1.698	1	8	342
GO:0005515	protein binding	2.71e-01	1.00e+00	0.366	7	62	6024
GO:0043066	negative regulation of apoptotic process	3.22e-01	1.00e+00	1.388	1	13	424
GO:0055085	transmembrane transport	3.29e-01	1.00e+00	1.351	1	3	435
GO:0048471	perinuclear region of cytoplasm	3.69e-01	1.00e+00	1.144	1	7	502
GO:0005783	endoplasmic reticulum	4.00e-01	1.00e+00	0.997	1	3	556
GO:0005794	Golgi apparatus	4.30e-01	1.00e+00	0.863	1	9	610
GO:0005615	extracellular space	5.91e-01	1.00e+00	0.213	1	2	957
GO:0005634	nucleus	6.28e-01	1.00e+00	-0.039	4	43	4559
GO:0046872	metal ion binding	7.09e-01	1.00e+00	-0.236	1	10	1307

Tai-Luciferase

int-snw-51382

Statistics

Genes (13)

Interactions (25)

Related GO terms (102)