reg-snw-988

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	5.672	6.20e-37	3.20e-06	7.14e-06

tai-screen-luciferase-reg-snw-988 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
TLK2	11011	8	-4.011	5.672	14	-	-	-
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes
[ CDC5L ]	988	15	-3.419	5.672	155	TF	-	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot

Related GO terms (68)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0071987	WD40-repeat domain binding	5.12e-04	1.00e+00	10.931	1	1	1
GO:0002176	male germ cell proliferation	1.02e-03	1.00e+00	9.931	1	1	2
GO:0001672	regulation of chromatin assembly or disassembly	1.02e-03	1.00e+00	9.931	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.02e-03	1.00e+00	9.931	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.02e-03	1.00e+00	9.931	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	1.54e-03	1.00e+00	9.347	1	1	3
GO:0050658	RNA transport	2.05e-03	1.00e+00	8.931	1	1	4
GO:0030157	pancreatic juice secretion	2.05e-03	1.00e+00	8.931	1	1	4
GO:0000974	Prp19 complex	2.56e-03	1.00e+00	8.610	1	1	5
GO:0000930	gamma-tubulin complex	2.56e-03	1.00e+00	8.610	1	1	5
GO:0030126	COPI vesicle coat	3.58e-03	1.00e+00	8.124	1	1	7
GO:0005662	DNA replication factor A complex	4.09e-03	1.00e+00	7.931	1	1	8
GO:0071480	cellular response to gamma radiation	5.11e-03	1.00e+00	7.610	1	1	10
GO:0010507	negative regulation of autophagy	5.11e-03	1.00e+00	7.610	1	1	10
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	5.11e-03	1.00e+00	7.610	1	1	10
GO:0007051	spindle organization	5.11e-03	1.00e+00	7.610	1	1	10
GO:0051297	centrosome organization	6.13e-03	1.00e+00	7.347	1	1	12
GO:0048205	COPI coating of Golgi vesicle	6.13e-03	1.00e+00	7.347	1	1	12
GO:0035371	microtubule plus-end	6.64e-03	1.00e+00	7.231	1	1	13
GO:0008135	translation factor activity, nucleic acid binding	7.66e-03	1.00e+00	7.025	1	4	15
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	8.68e-03	1.00e+00	6.844	1	1	17
GO:0016020	membrane	1.55e-02	1.00e+00	2.279	3	25	1207
GO:0003743	translation initiation factor activity	1.88e-02	1.00e+00	5.722	1	5	37
GO:0005882	intermediate filament	2.03e-02	1.00e+00	5.610	1	2	40
GO:0007059	chromosome segregation	2.53e-02	1.00e+00	5.288	1	1	50
GO:0018105	peptidyl-serine phosphorylation	2.58e-02	1.00e+00	5.259	1	2	51
GO:0008584	male gonad development	2.89e-02	1.00e+00	5.099	1	1	57
GO:0005179	hormone activity	3.04e-02	1.00e+00	5.025	1	1	60
GO:0071013	catalytic step 2 spliceosome	3.09e-02	1.00e+00	5.001	1	1	61
GO:0000922	spindle pole	3.43e-02	1.00e+00	4.844	1	3	68
GO:0016568	chromatin modification	3.43e-02	1.00e+00	4.844	1	2	68
GO:0015630	microtubule cytoskeleton	3.78e-02	1.00e+00	4.703	1	2	75
GO:0006886	intracellular protein transport	4.48e-02	1.00e+00	4.456	1	1	89
GO:0061024	membrane organization	4.48e-02	1.00e+00	4.456	1	3	89
GO:0005829	cytosol	4.57e-02	1.00e+00	1.713	3	33	1787
GO:0000086	G2/M transition of mitotic cell cycle	4.87e-02	1.00e+00	4.332	1	3	97
GO:0006413	translational initiation	4.97e-02	1.00e+00	4.302	1	12	99
GO:0005198	structural molecule activity	5.07e-02	1.00e+00	4.273	1	1	101
GO:0044822	poly(A) RNA binding	5.66e-02	1.00e+00	2.289	2	25	799
GO:0007049	cell cycle	5.75e-02	1.00e+00	4.086	1	2	115
GO:0006974	cellular response to DNA damage stimulus	6.05e-02	1.00e+00	4.013	1	2	121
GO:0016607	nuclear speck	6.09e-02	1.00e+00	4.001	1	2	122
GO:0000398	mRNA splicing, via spliceosome	6.39e-02	1.00e+00	3.931	1	2	128
GO:0001701	in utero embryonic development	7.64e-02	1.00e+00	3.665	1	2	154
GO:0007067	mitotic nuclear division	8.17e-02	1.00e+00	3.565	1	5	165
GO:0006412	translation	8.79e-02	1.00e+00	3.456	1	13	178
GO:0004674	protein serine/threonine kinase activity	9.69e-02	1.00e+00	3.309	1	3	197
GO:0035556	intracellular signal transduction	9.78e-02	1.00e+00	3.295	1	3	199
GO:0043234	protein complex	1.03e-01	1.00e+00	3.217	1	8	210
GO:0005515	protein binding	1.05e-01	1.00e+00	0.922	4	50	4124
GO:0005813	centrosome	1.06e-01	1.00e+00	3.170	1	6	217
GO:0005730	nucleolus	1.20e-01	1.00e+00	1.682	2	21	1217
GO:0003723	RNA binding	1.20e-01	1.00e+00	2.983	1	6	247
GO:0003682	chromatin binding	1.23e-01	1.00e+00	2.954	1	3	252
GO:0006468	protein phosphorylation	1.45e-01	1.00e+00	2.698	1	3	301
GO:0000278	mitotic cell cycle	1.51e-01	1.00e+00	2.637	1	9	314
GO:0048471	perinuclear region of cytoplasm	1.64e-01	1.00e+00	2.505	1	7	344
GO:0044267	cellular protein metabolic process	1.68e-01	1.00e+00	2.472	1	13	352
GO:0010467	gene expression	2.46e-01	1.00e+00	1.868	1	17	535
GO:0005615	extracellular space	2.92e-01	1.00e+00	1.585	1	2	651
GO:0006355	regulation of transcription, DNA-templated	3.16e-01	1.00e+00	1.450	1	9	715
GO:0005524	ATP binding	3.81e-01	1.00e+00	1.131	1	10	892
GO:0046872	metal ion binding	3.95e-01	1.00e+00	1.064	1	10	934
GO:0003677	DNA binding	4.00e-01	1.00e+00	1.044	1	12	947
GO:0005737	cytoplasm	4.09e-01	1.00e+00	0.569	2	39	2633
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	15	1076
GO:0005634	nucleus	5.37e-01	1.00e+00	0.267	2	40	3246
GO:0070062	extracellular vesicular exosome	6.02e-01	1.00e+00	0.251	1	28	1641

Tai-Luciferase

reg-snw-988

Statistics

Genes (5)

Interactions (4)

Related GO terms (68)