reg-snw-55869

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.752	5.69e-25	4.24e-04	6.99e-04

tai-screen-luciferase-reg-snw-55869 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
WDR18	57418	1	2.322	4.752	213	TF	-	-
RPS19	6223	2	-4.701	4.752	31	-	Yes	-
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
[ HDAC8 ]	55869	1	1.228	4.752	16	-	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes
CDC5L	988	15	-3.419	5.672	155	TF	-	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CKAP5	9793	HDAC8	55869	pd	>	reg.ITFP.txt: no annot
MRPS12	6183	WDR18	57418	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
HDAC8	55869	WDR18	57418	pd	<	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	HDAC8	55869	pd	>	reg.ITFP.txt: no annot
MRPS12	6183	HDAC8	55869	pd	>	reg.ITFP.txt: no annot
RPS19	6223	WDR18	57418	pd	<	reg.ITFP.txt: no annot

Related GO terms (102)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006412	translation	3.12e-04	1.00e+00	4.363	3	13	178
GO:0071987	WD40-repeat domain binding	8.19e-04	1.00e+00	10.253	1	1	1
GO:0002176	male germ cell proliferation	1.64e-03	1.00e+00	9.253	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.64e-03	1.00e+00	9.253	1	1	2
GO:0060265	positive regulation of respiratory burst involved in inflammatory response	1.64e-03	1.00e+00	9.253	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.64e-03	1.00e+00	9.253	1	1	2
GO:0044822	poly(A) RNA binding	2.38e-03	1.00e+00	2.611	4	25	799
GO:0005850	eukaryotic translation initiation factor 2 complex	2.46e-03	1.00e+00	8.668	1	1	3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	2.46e-03	1.00e+00	8.668	1	1	3
GO:0009991	response to extracellular stimulus	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006413	translational initiation	2.74e-03	1.00e+00	4.624	2	12	99
GO:0050658	RNA transport	3.27e-03	1.00e+00	8.253	1	1	4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.27e-03	1.00e+00	8.253	1	1	4
GO:0007000	nucleolus organization	3.27e-03	1.00e+00	8.253	1	2	4
GO:0030157	pancreatic juice secretion	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006333	chromatin assembly or disassembly	3.27e-03	1.00e+00	8.253	1	1	4
GO:0030490	maturation of SSU-rRNA	3.27e-03	1.00e+00	8.253	1	2	4
GO:0071922	regulation of cohesin localization to chromatin	3.27e-03	1.00e+00	8.253	1	2	4
GO:0003735	structural constituent of ribosome	3.31e-03	1.00e+00	4.485	2	8	109
GO:0000974	Prp19 complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000930	gamma-tubulin complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000028	ribosomal small subunit assembly	4.09e-03	1.00e+00	7.931	1	3	5
GO:0030126	COPI vesicle coat	5.72e-03	1.00e+00	7.446	1	1	7
GO:0005662	DNA replication factor A complex	6.54e-03	1.00e+00	7.253	1	1	8
GO:0097372	NAD-dependent histone deacetylase activity (H3-K18 specific)	6.54e-03	1.00e+00	7.253	1	1	8
GO:0005829	cytosol	6.99e-03	1.00e+00	1.772	5	33	1787
GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)	7.35e-03	1.00e+00	7.083	1	1	9
GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)	7.35e-03	1.00e+00	7.083	1	1	9
GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)	7.35e-03	1.00e+00	7.083	1	1	9
GO:0061647	histone H3-K9 modification	7.35e-03	1.00e+00	7.083	1	1	9
GO:0007062	sister chromatid cohesion	7.35e-03	1.00e+00	7.083	1	1	9
GO:0007051	spindle organization	8.17e-03	1.00e+00	6.931	1	1	10
GO:0051272	positive regulation of cellular component movement	8.98e-03	1.00e+00	6.794	1	1	11
GO:0070933	histone H4 deacetylation	8.98e-03	1.00e+00	6.794	1	1	11
GO:0042274	ribosomal small subunit biogenesis	8.98e-03	1.00e+00	6.794	1	3	11
GO:0015935	small ribosomal subunit	9.79e-03	1.00e+00	6.668	1	4	12
GO:0051297	centrosome organization	9.79e-03	1.00e+00	6.668	1	1	12
GO:0048205	COPI coating of Golgi vesicle	9.79e-03	1.00e+00	6.668	1	1	12
GO:0004407	histone deacetylase activity	9.79e-03	1.00e+00	6.668	1	1	12
GO:0035371	microtubule plus-end	1.06e-02	1.00e+00	6.553	1	1	13
GO:0017134	fibroblast growth factor binding	1.06e-02	1.00e+00	6.553	1	2	13
GO:0016020	membrane	1.08e-02	1.00e+00	2.016	4	25	1207
GO:0002548	monocyte chemotaxis	1.14e-02	1.00e+00	6.446	1	1	14
GO:0008135	translation factor activity, nucleic acid binding	1.22e-02	1.00e+00	6.347	1	4	15
GO:0070932	histone H3 deacetylation	1.22e-02	1.00e+00	6.347	1	1	15
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.38e-02	1.00e+00	6.166	1	1	17
GO:0005761	mitochondrial ribosome	1.63e-02	1.00e+00	5.931	1	1	20
GO:0051262	protein tetramerization	1.87e-02	1.00e+00	5.730	1	1	23
GO:0000118	histone deacetylase complex	1.87e-02	1.00e+00	5.730	1	1	23
GO:0000228	nuclear chromosome	2.27e-02	1.00e+00	5.446	1	1	28
GO:0022627	cytosolic small ribosomal subunit	2.43e-02	1.00e+00	5.347	1	6	30
GO:0000278	mitotic cell cycle	2.54e-02	1.00e+00	2.959	2	9	314
GO:0030218	erythrocyte differentiation	2.67e-02	1.00e+00	5.209	1	2	33
GO:0003743	translation initiation factor activity	2.99e-02	1.00e+00	5.044	1	5	37
GO:0044267	cellular protein metabolic process	3.14e-02	1.00e+00	2.794	2	13	352
GO:0005840	ribosome	3.23e-02	1.00e+00	4.931	1	3	40
GO:0005737	cytoplasm	3.74e-02	1.00e+00	1.213	5	39	2633
GO:0008584	male gonad development	4.58e-02	1.00e+00	4.421	1	1	57
GO:0005179	hormone activity	4.81e-02	1.00e+00	4.347	1	1	60
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	1	61
GO:0019083	viral transcription	4.89e-02	1.00e+00	4.323	1	7	61
GO:0006415	translational termination	5.05e-02	1.00e+00	4.276	1	7	63
GO:0006364	rRNA processing	5.36e-02	1.00e+00	4.187	1	5	67
GO:0000922	spindle pole	5.44e-02	1.00e+00	4.166	1	3	68
GO:0016568	chromatin modification	5.44e-02	1.00e+00	4.166	1	2	68
GO:0006414	translational elongation	5.52e-02	1.00e+00	4.145	1	7	69
GO:0015630	microtubule cytoskeleton	5.98e-02	1.00e+00	4.025	1	2	75
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	6.14e-02	1.00e+00	3.987	1	7	77
GO:0019058	viral life cycle	6.22e-02	1.00e+00	3.968	1	8	78
GO:0005515	protein binding	6.50e-02	1.00e+00	0.829	6	50	4124
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	7	84
GO:0010467	gene expression	6.73e-02	1.00e+00	2.190	2	17	535
GO:0006886	intracellular protein transport	7.07e-02	1.00e+00	3.778	1	1	89
GO:0061024	membrane organization	7.07e-02	1.00e+00	3.778	1	3	89
GO:0000086	G2/M transition of mitotic cell cycle	7.68e-02	1.00e+00	3.653	1	3	97
GO:0005198	structural molecule activity	7.98e-02	1.00e+00	3.595	1	1	101
GO:0016607	nuclear speck	9.57e-02	1.00e+00	3.323	1	2	122
GO:0000398	mRNA splicing, via spliceosome	1.00e-01	1.00e+00	3.253	1	2	128
GO:0001701	in utero embryonic development	1.19e-01	1.00e+00	2.987	1	2	154
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	5	165
GO:0016071	mRNA metabolic process	1.31e-01	1.00e+00	2.844	1	11	170
GO:0016070	RNA metabolic process	1.44e-01	1.00e+00	2.699	1	11	188
GO:0008134	transcription factor binding	1.59e-01	1.00e+00	2.546	1	5	209
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	8	210
GO:0007275	multicellular organismal development	1.62e-01	1.00e+00	2.512	1	1	214
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	6	217
GO:0046872	metal ion binding	1.74e-01	1.00e+00	1.386	2	10	934
GO:0019901	protein kinase binding	1.75e-01	1.00e+00	2.395	1	8	232
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	6	247
GO:0003682	chromatin binding	1.89e-01	1.00e+00	2.276	1	3	252
GO:0005925	focal adhesion	2.09e-01	1.00e+00	2.114	1	12	282
GO:0006351	transcription, DNA-templated	2.18e-01	1.00e+00	1.182	2	15	1076
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	21	1217
GO:0042803	protein homodimerization activity	3.01e-01	1.00e+00	1.512	1	4	428
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	6	456
GO:0070062	extracellular vesicular exosome	4.00e-01	1.00e+00	0.573	2	28	1641
GO:0005615	extracellular space	4.24e-01	1.00e+00	0.907	1	2	651
GO:0006355	regulation of transcription, DNA-templated	4.56e-01	1.00e+00	0.772	1	9	715
GO:0005654	nucleoplasm	5.29e-01	1.00e+00	0.479	1	16	876
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	12	947
GO:0005634	nucleus	8.04e-01	1.00e+00	-0.411	2	40	3246

Tai-Luciferase

reg-snw-55869

Statistics

Genes (8)

Interactions (9)

Related GO terms (102)