reg-snw-84343

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.236	2.24e-19	3.52e-03	4.83e-03

tai-screen-luciferase-reg-snw-84343 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
BRCA2	675	1	-1.991	4.236	111	TF	-	-
[ HPS3 ]	84343	1	-1.516	4.236	41	-	-	-
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
CTSF	8722	1	-3.978	4.236	1	-	-	Yes
UTP18	51096	1	-1.709	4.236	106	TF	-	-
RPS14	6208	1	-4.803	4.236	13	-	Yes	-
TLK2	11011	8	-4.011	5.672	14	-	-	-
CDC5L	988	15	-3.419	5.672	155	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
UTP18	51096	HPS3	84343	pd	>	reg.ITFP.txt: no annot
COPA	1314	HPS3	84343	pd	>	reg.ITFP.txt: no annot
BRCA2	675	CTSF	8722	pd	>	reg.ITFP.txt: no annot
RPS14	6208	UTP18	51096	pd	<	reg.ITFP.txt: no annot
BRCA2	675	HPS3	84343	pd	>	reg.ITFP.txt: no annot
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	HPS3	84343	pd	>	reg.ITFP.txt: no annot

Related GO terms (133)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0033593	BRCA2-MAGE-D1 complex	1.02e-03	1.00e+00	9.931	1	1	1
GO:0010484	H3 histone acetyltransferase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0071987	WD40-repeat domain binding	1.02e-03	1.00e+00	9.931	1	1	1
GO:0001672	regulation of chromatin assembly or disassembly	2.05e-03	1.00e+00	8.931	1	1	2
GO:0002176	male germ cell proliferation	2.05e-03	1.00e+00	8.931	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	2.05e-03	1.00e+00	8.931	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	2.05e-03	1.00e+00	8.931	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	3.07e-03	1.00e+00	8.347	1	1	3
GO:0010485	H4 histone acetyltransferase activity	3.07e-03	1.00e+00	8.347	1	1	3
GO:0031084	BLOC-2 complex	3.07e-03	1.00e+00	8.347	1	1	3
GO:0050658	RNA transport	4.09e-03	1.00e+00	7.931	1	1	4
GO:0030157	pancreatic juice secretion	4.09e-03	1.00e+00	7.931	1	1	4
GO:0030490	maturation of SSU-rRNA	4.09e-03	1.00e+00	7.931	1	2	4
GO:0048478	replication fork protection	4.09e-03	1.00e+00	7.931	1	1	4
GO:0006413	translational initiation	4.34e-03	1.00e+00	4.302	2	12	99
GO:0005730	nucleolus	4.37e-03	1.00e+00	2.004	5	21	1217
GO:0000974	Prp19 complex	5.11e-03	1.00e+00	7.610	1	1	5
GO:0000028	ribosomal small subunit assembly	5.11e-03	1.00e+00	7.610	1	3	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	5.11e-03	1.00e+00	7.610	1	1	5
GO:0000930	gamma-tubulin complex	5.11e-03	1.00e+00	7.610	1	1	5
GO:0045182	translation regulator activity	6.13e-03	1.00e+00	7.347	1	1	6
GO:0044822	poly(A) RNA binding	6.26e-03	1.00e+00	2.289	4	25	799
GO:0048027	mRNA 5'-UTR binding	7.15e-03	1.00e+00	7.124	1	1	7
GO:0030126	COPI vesicle coat	7.15e-03	1.00e+00	7.124	1	1	7
GO:0005662	DNA replication factor A complex	8.17e-03	1.00e+00	6.931	1	1	8
GO:0006996	organelle organization	8.17e-03	1.00e+00	6.931	1	1	8
GO:0001833	inner cell mass cell proliferation	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010225	response to UV-C	9.18e-03	1.00e+00	6.762	1	1	9
GO:0007141	male meiosis I	1.02e-02	1.00e+00	6.610	1	1	10
GO:0071480	cellular response to gamma radiation	1.02e-02	1.00e+00	6.610	1	1	10
GO:0008585	female gonad development	1.02e-02	1.00e+00	6.610	1	1	10
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1.02e-02	1.00e+00	6.610	1	1	10
GO:0007051	spindle organization	1.02e-02	1.00e+00	6.610	1	1	10
GO:0051298	centrosome duplication	1.02e-02	1.00e+00	6.610	1	1	10
GO:0010507	negative regulation of autophagy	1.02e-02	1.00e+00	6.610	1	1	10
GO:0043015	gamma-tubulin binding	1.02e-02	1.00e+00	6.610	1	2	10
GO:0032465	regulation of cytokinesis	1.02e-02	1.00e+00	6.610	1	1	10
GO:0001556	oocyte maturation	1.12e-02	1.00e+00	6.472	1	1	11
GO:0051297	centrosome organization	1.22e-02	1.00e+00	6.347	1	1	12
GO:0048205	COPI coating of Golgi vesicle	1.22e-02	1.00e+00	6.347	1	1	12
GO:0035371	microtubule plus-end	1.32e-02	1.00e+00	6.231	1	1	13
GO:0043473	pigmentation	1.32e-02	1.00e+00	6.231	1	1	13
GO:0006412	translation	1.35e-02	1.00e+00	3.456	2	13	178
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	1.43e-02	1.00e+00	6.124	1	1	14
GO:0008135	translation factor activity, nucleic acid binding	1.53e-02	1.00e+00	6.025	1	4	15
GO:0010165	response to X-ray	1.73e-02	1.00e+00	5.844	1	1	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.73e-02	1.00e+00	5.844	1	1	17
GO:0043234	protein complex	1.85e-02	1.00e+00	3.217	2	8	210
GO:0005813	centrosome	1.97e-02	1.00e+00	3.170	2	6	217
GO:0007569	cell aging	2.13e-02	1.00e+00	5.539	1	1	21
GO:0043967	histone H4 acetylation	2.23e-02	1.00e+00	5.472	1	2	22
GO:0045931	positive regulation of mitotic cell cycle	2.33e-02	1.00e+00	5.408	1	2	23
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.43e-02	1.00e+00	5.347	1	1	24
GO:0003723	RNA binding	2.51e-02	1.00e+00	2.983	2	6	247
GO:0010332	response to gamma radiation	2.63e-02	1.00e+00	5.231	1	2	26
GO:0016020	membrane	2.64e-02	1.00e+00	1.694	4	25	1207
GO:0043966	histone H3 acetylation	2.83e-02	1.00e+00	5.124	1	1	28
GO:0004402	histone acetyltransferase activity	3.03e-02	1.00e+00	5.025	1	1	30
GO:0022627	cytosolic small ribosomal subunit	3.03e-02	1.00e+00	5.025	1	6	30
GO:0030218	erythrocyte differentiation	3.33e-02	1.00e+00	4.887	1	2	33
GO:0000910	cytokinesis	3.33e-02	1.00e+00	4.887	1	1	33
GO:0004197	cysteine-type endopeptidase activity	3.73e-02	1.00e+00	4.722	1	1	37
GO:0003743	translation initiation factor activity	3.73e-02	1.00e+00	4.722	1	5	37
GO:0043202	lysosomal lumen	3.92e-02	1.00e+00	4.646	1	1	39
GO:0006417	regulation of translation	3.92e-02	1.00e+00	4.646	1	3	39
GO:0005882	intermediate filament	4.02e-02	1.00e+00	4.610	1	2	40
GO:0000724	double-strand break repair via homologous recombination	4.22e-02	1.00e+00	4.539	1	1	42
GO:0030141	secretory granule	4.42e-02	1.00e+00	4.472	1	2	44
GO:0030097	hemopoiesis	4.81e-02	1.00e+00	4.347	1	1	48
GO:0044267	cellular protein metabolic process	4.82e-02	1.00e+00	2.472	2	13	352
GO:0007059	chromosome segregation	5.01e-02	1.00e+00	4.288	1	1	50
GO:0002020	protease binding	5.01e-02	1.00e+00	4.288	1	1	50
GO:0018105	peptidyl-serine phosphorylation	5.10e-02	1.00e+00	4.259	1	2	51
GO:0006302	double-strand break repair	5.20e-02	1.00e+00	4.231	1	1	52
GO:0006289	nucleotide-excision repair	5.30e-02	1.00e+00	4.204	1	1	53
GO:0008584	male gonad development	5.69e-02	1.00e+00	4.099	1	1	57
GO:0003697	single-stranded DNA binding	5.69e-02	1.00e+00	4.099	1	3	57
GO:0005179	hormone activity	5.98e-02	1.00e+00	4.025	1	1	60
GO:0071013	catalytic step 2 spliceosome	6.08e-02	1.00e+00	4.001	1	1	61
GO:0019083	viral transcription	6.08e-02	1.00e+00	4.001	1	7	61
GO:0006415	translational termination	6.27e-02	1.00e+00	3.954	1	7	63
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	6.37e-02	1.00e+00	3.931	1	3	64
GO:0006364	rRNA processing	6.66e-02	1.00e+00	3.865	1	5	67
GO:0000922	spindle pole	6.75e-02	1.00e+00	3.844	1	3	68
GO:0016568	chromatin modification	6.75e-02	1.00e+00	3.844	1	2	68
GO:0006414	translational elongation	6.85e-02	1.00e+00	3.823	1	7	69
GO:0015630	microtubule cytoskeleton	7.42e-02	1.00e+00	3.703	1	2	75
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.61e-02	1.00e+00	3.665	1	7	77
GO:0019058	viral life cycle	7.71e-02	1.00e+00	3.646	1	8	78
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.28e-02	1.00e+00	3.539	1	7	84
GO:0031982	vesicle	8.56e-02	1.00e+00	3.489	1	1	87
GO:0061024	membrane organization	8.75e-02	1.00e+00	3.456	1	3	89
GO:0006886	intracellular protein transport	8.75e-02	1.00e+00	3.456	1	1	89
GO:0005829	cytosol	9.28e-02	1.00e+00	1.128	4	33	1787
GO:0000086	G2/M transition of mitotic cell cycle	9.51e-02	1.00e+00	3.332	1	3	97
GO:0005764	lysosome	9.79e-02	1.00e+00	3.288	1	1	100
GO:0005198	structural molecule activity	9.88e-02	1.00e+00	3.273	1	1	101
GO:0010467	gene expression	1.01e-01	1.00e+00	1.868	2	17	535
GO:0003735	structural constituent of ribosome	1.06e-01	1.00e+00	3.163	1	8	109
GO:0007049	cell cycle	1.12e-01	1.00e+00	3.086	1	2	115
GO:0007420	brain development	1.15e-01	1.00e+00	3.037	1	2	119
GO:0006974	cellular response to DNA damage stimulus	1.17e-01	1.00e+00	3.013	1	2	121
GO:0016607	nuclear speck	1.18e-01	1.00e+00	3.001	1	2	122
GO:0000398	mRNA splicing, via spliceosome	1.24e-01	1.00e+00	2.931	1	2	128
GO:0001701	in utero embryonic development	1.47e-01	1.00e+00	2.665	1	2	154
GO:0007067	mitotic nuclear division	1.57e-01	1.00e+00	2.565	1	5	165
GO:0007283	spermatogenesis	1.59e-01	1.00e+00	2.539	1	2	168
GO:0016071	mRNA metabolic process	1.61e-01	1.00e+00	2.522	1	11	170
GO:0016070	RNA metabolic process	1.77e-01	1.00e+00	2.377	1	11	188
GO:0004674	protein serine/threonine kinase activity	1.84e-01	1.00e+00	2.309	1	3	197
GO:0035556	intracellular signal transduction	1.86e-01	1.00e+00	2.295	1	3	199
GO:0006281	DNA repair	1.90e-01	1.00e+00	2.266	1	2	203
GO:0070062	extracellular vesicular exosome	2.29e-01	1.00e+00	0.836	3	28	1641
GO:0003682	chromatin binding	2.30e-01	1.00e+00	1.954	1	3	252
GO:0006508	proteolysis	2.40e-01	1.00e+00	1.887	1	1	264
GO:0005925	focal adhesion	2.54e-01	1.00e+00	1.792	1	12	282
GO:0006468	protein phosphorylation	2.69e-01	1.00e+00	1.698	1	3	301
GO:0000278	mitotic cell cycle	2.79e-01	1.00e+00	1.637	1	9	314
GO:0048471	perinuclear region of cytoplasm	3.01e-01	1.00e+00	1.505	1	7	344
GO:0045893	positive regulation of transcription, DNA-templated	3.26e-01	1.00e+00	1.373	1	6	377
GO:0016032	viral process	3.61e-01	1.00e+00	1.190	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.099	1	6	456
GO:0005515	protein binding	4.24e-01	1.00e+00	0.244	5	50	4124
GO:0005634	nucleus	4.38e-01	1.00e+00	0.267	4	40	3246
GO:0005615	extracellular space	4.99e-01	1.00e+00	0.585	1	2	651
GO:0005739	mitochondrion	5.03e-01	1.00e+00	0.567	1	4	659
GO:0005737	cytoplasm	5.33e-01	1.00e+00	0.154	3	39	2633
GO:0006355	regulation of transcription, DNA-templated	5.33e-01	1.00e+00	0.450	1	9	715
GO:0005654	nucleoplasm	6.10e-01	1.00e+00	0.157	1	16	876
GO:0005524	ATP binding	6.16e-01	1.00e+00	0.131	1	10	892
GO:0046872	metal ion binding	6.34e-01	1.00e+00	0.064	1	10	934
GO:0003677	DNA binding	6.40e-01	1.00e+00	0.044	1	12	947
GO:0006351	transcription, DNA-templated	6.89e-01	1.00e+00	-0.140	1	15	1076

Tai-Luciferase

reg-snw-84343

Statistics

Genes (10)

Interactions (10)

Related GO terms (133)