Related GO terms (1278)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway135
GO:0008083growth factor activity1145
GO:0000381regulation of alternative mRNA splicing, via spliceosome129
GO:2001286regulation of caveolin-mediated endocytosis11
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process144
GO:0050796regulation of insulin secretion182
GO:0051443positive regulation of ubiquitin-protein transferase activity115
GO:0030038contractile actin filament bundle assembly11
GO:0043353enucleate erythrocyte differentiation16
GO:0005769early endosome1158
GO:0032088negative regulation of NF-kappaB transcription factor activity164
GO:0032839dendrite cytoplasm116
GO:0050847progesterone receptor signaling pathway16
GO:0001525angiogenesis3200
GO:0002053positive regulation of mesenchymal cell proliferation133
GO:0007286spermatid development144
GO:0008360regulation of cell shape2106
GO:0031333negative regulation of protein complex assembly114
GO:0031252cell leading edge329
GO:0003677DNA binding141351
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity111
GO:0030168platelet activation4205
GO:0003725double-stranded RNA binding254
GO:0045176apical protein localization111
GO:0033209tumor necrosis factor-mediated signaling pathway128
GO:0032863activation of Rac GTPase activity110
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process236
GO:0004872receptor activity1199
GO:0051092positive regulation of NF-kappaB transcription factor activity3125
GO:0016601Rac protein signal transduction117
GO:0045171intercellular bridge231
GO:0051149positive regulation of muscle cell differentiation227
GO:0032781positive regulation of ATPase activity125
GO:0007143female meiotic division16
GO:0048010vascular endothelial growth factor receptor signaling pathway121
GO:0000045autophagic vacuole assembly126
GO:0016310phosphorylation195
GO:0071922regulation of cohesin localization to chromatin24
GO:0030316osteoclast differentiation122
GO:0034191apolipoprotein A-I receptor binding14
GO:0007051spindle organization112
GO:1990138neuron projection extension15
GO:0004888transmembrane signaling receptor activity1103
GO:0030705cytoskeleton-dependent intracellular transport114
GO:0001102RNA polymerase II activating transcription factor binding137
GO:0045892negative regulation of transcription, DNA-templated2424
GO:0032467positive regulation of cytokinesis128
GO:0008017microtubule binding2150
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway13
GO:2000641regulation of early endosome to late endosome transport15
GO:0036336dendritic cell migration15
GO:0004305ethanolamine kinase activity14
GO:0051084'de novo' posttranslational protein folding237
GO:0042789mRNA transcription from RNA polymerase II promoter113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding13
GO:007188914-3-3 protein binding118
GO:0010977negative regulation of neuron projection development230
GO:0008283cell proliferation4331
GO:0035255ionotropic glutamate receptor binding117
GO:0002548monocyte chemotaxis117
GO:0006974cellular response to DNA damage stimulus3158
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage249
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoter17
GO:0005070SH3/SH2 adaptor activity149
GO:0051491positive regulation of filopodium assembly223
GO:0030336negative regulation of cell migration283
GO:0001947heart looping149
GO:0016282eukaryotic 43S preinitiation complex114
GO:0030246carbohydrate binding1151
GO:0032012regulation of ARF protein signal transduction116
GO:0008284positive regulation of cell proliferation7392
GO:0034314Arp2/3 complex-mediated actin nucleation111
GO:0001568blood vessel development238
GO:0034134toll-like receptor 2 signaling pathway573
GO:0090005negative regulation of establishment of protein localization to plasma membrane18
GO:0007131reciprocal meiotic recombination124
GO:0045182translation regulator activity26
GO:0006612protein targeting to membrane218
GO:0014809regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion13
GO:0007165signal transduction7950
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay22114
GO:0008481sphinganine kinase activity12
GO:0046777protein autophosphorylation1158
GO:0006893Golgi to plasma membrane transport17
GO:0032873negative regulation of stress-activated MAPK cascade16
GO:0000151ubiquitin ligase complex163
GO:0071987WD40-repeat domain binding12
GO:0045944positive regulation of transcription from RNA polymerase II promoter11811
GO:0051726regulation of cell cycle2102
GO:0004588orotate phosphoribosyltransferase activity11
GO:0090284positive regulation of protein glycosylation in Golgi11
GO:0051402neuron apoptotic process136
GO:0000779condensed chromosome, centromeric region15
GO:0055114oxidation-reduction process2481
GO:0034237protein kinase A regulatory subunit binding110
GO:0090009primitive streak formation18
GO:0005901caveola163
GO:0034162toll-like receptor 9 signaling pathway572
GO:0003712transcription cofactor activity144
GO:0040038polar body extrusion after meiotic divisions14
GO:0007229integrin-mediated signaling pathway278
GO:0016591DNA-directed RNA polymerase II, holoenzyme19
GO:0001671ATPase activator activity113
GO:0045111intermediate filament cytoskeleton149
GO:0060947cardiac vascular smooth muscle cell differentiation13
GO:0005882intermediate filament366
GO:0051895negative regulation of focal adhesion assembly111
GO:2000651positive regulation of sodium ion transmembrane transporter activity15
GO:0006954inflammatory response1289
GO:0043966histone H3 acetylation145
GO:0006952defense response153
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain14
GO:0019083viral transcription2281
GO:0008134transcription factor binding5246
GO:0060337type I interferon signaling pathway163
GO:0005783endoplasmic reticulum6610
GO:0005847mRNA cleavage and polyadenylation specificity factor complex19
GO:0071944cell periphery123
GO:0060661submandibular salivary gland formation12
GO:0031982vesicle2134
GO:0019058viral life cycle25115
GO:0030426growth cone397
GO:0003697single-stranded DNA binding469
GO:0043065positive regulation of apoptotic process6274
GO:0097193intrinsic apoptotic signaling pathway255
GO:0045087innate immune response11616
GO:0005158insulin receptor binding233
GO:0009612response to mechanical stimulus154
GO:0005125cytokine activity1146
GO:0030154cell differentiation3325
GO:0000398mRNA splicing, via spliceosome2165
GO:0004590orotidine-5'-phosphate decarboxylase activity11
GO:0070933histone H4 deacetylation117
GO:0043066negative regulation of apoptotic process14433
GO:0032855positive regulation of Rac GTPase activity136
GO:0048478replication fork protection14
GO:0016032viral process37540
GO:0001666response to hypoxia1150
GO:0008022protein C-terminus binding4161
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress124
GO:0035063nuclear speck organization11
GO:0006367transcription initiation from RNA polymerase II promoter5184
GO:0045120pronucleus111
GO:0019242methylglyoxal biosynthetic process11
GO:0032148activation of protein kinase B activity120
GO:0051117ATPase binding241
GO:0035556intracellular signal transduction5317
GO:0051150regulation of smooth muscle cell differentiation16
GO:0002474antigen processing and presentation of peptide antigen via MHC class I794
GO:0002042cell migration involved in sprouting angiogenesis115
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening125
GO:0030225macrophage differentiation115
GO:0048037cofactor binding116
GO:0005871kinesin complex144
GO:0002039p53 binding155
GO:0000800lateral element18
GO:0006366transcription from RNA polymerase II promoter3425
GO:0000228nuclear chromosome236
GO:0001817regulation of cytokine production110
GO:0019904protein domain specific binding3181
GO:0032480negative regulation of type I interferon production232
GO:0019899enzyme binding5288
GO:0050662coenzyme binding114
GO:0045056transcytosis16
GO:0036035osteoclast development12
GO:0001649osteoblast differentiation395
GO:0060789hair follicle placode formation16
GO:0034644cellular response to UV132
GO:0033176proton-transporting V-type ATPase complex11
GO:0042474middle ear morphogenesis121
GO:0048318axial mesoderm development13
GO:0008090retrograde axon cargo transport16
GO:0008307structural constituent of muscle141
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)35
GO:0005654nucleoplasm261095
GO:0007507heart development1141
GO:0031512motile primary cilium18
GO:0042826histone deacetylase binding174
GO:0047498calcium-dependent phospholipase A2 activity18
GO:0031902late endosome membrane180
GO:0018105peptidyl-serine phosphorylation569
GO:0033365protein localization to organelle117
GO:0007220Notch receptor processing222
GO:0075733intracellular transport of virus317
GO:0090045positive regulation of deacetylase activity13
GO:0002183cytoplasmic translational initiation11
GO:0000776kinetochore363
GO:1990077primosome complex22
GO:0051782negative regulation of cell division15
GO:0000922spindle pole591
GO:0006269DNA replication, synthesis of RNA primer25
GO:0000502proteasome complex458
GO:0007088regulation of mitosis119
GO:0000122negative regulation of transcription from RNA polymerase II promoter9589
GO:0090398cellular senescence120
GO:0060136embryonic process involved in female pregnancy17
GO:0046329negative regulation of JNK cascade124
GO:0007163establishment or maintenance of cell polarity224
GO:0043202lysosomal lumen166
GO:0043525positive regulation of neuron apoptotic process246
GO:0050900leukocyte migration1111
GO:0051090regulation of sequence-specific DNA binding transcription factor activity220
GO:0030218erythrocyte differentiation238
GO:0071013catalytic step 2 spliceosome179
GO:0032869cellular response to insulin stimulus264
GO:0035033histone deacetylase regulator activity13
GO:0030529ribonucleoprotein complex8114
GO:0051301cell division281
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process879
GO:0016514SWI/SNF complex115
GO:0007346regulation of mitotic cell cycle330
GO:0043274phospholipase binding117
GO:0001890placenta development134
GO:2000017positive regulation of determination of dorsal identity13
GO:0003690double-stranded DNA binding291
GO:0017148negative regulation of translation141
GO:0071902positive regulation of protein serine/threonine kinase activity126
GO:0031234extrinsic component of cytoplasmic side of plasma membrane125
GO:0044822poly(A) RNA binding421078
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity143
GO:0000983RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity19
GO:0010628positive regulation of gene expression4149
GO:0048471perinuclear region of cytoplasm9523
GO:0007275multicellular organismal development2344
GO:0008380RNA splicing5232
GO:0045787positive regulation of cell cycle223
GO:0003723RNA binding10355
GO:0019226transmission of nerve impulse116
GO:0022625cytosolic large ribosomal subunit149
GO:0003730mRNA 3'-UTR binding129
GO:0007283spermatogenesis2276
GO:0051787misfolded protein binding110
GO:2001237negative regulation of extrinsic apoptotic signaling pathway135
GO:0097300programmed necrotic cell death15
GO:0016021integral component of membrane42483
GO:0019843rRNA binding427
GO:0015036disulfide oxidoreductase activity14
GO:0051835positive regulation of synapse structural plasticity14
GO:0018279protein N-linked glycosylation via asparagine191
GO:0010165response to X-ray119
GO:0071168protein localization to chromatin15
GO:0061024membrane organization11146
GO:0032403protein complex binding2185
GO:0000132establishment of mitotic spindle orientation216
GO:0015671oxygen transport114
GO:0032587ruffle membrane172
GO:0014835myoblast differentiation involved in skeletal muscle regeneration11
GO:0032092positive regulation of protein binding139
GO:0060292long term synaptic depression114
GO:0071363cellular response to growth factor stimulus142
GO:0006909phagocytosis131
GO:0004586ornithine decarboxylase activity11
GO:0031256leading edge membrane15
GO:0030433ER-associated ubiquitin-dependent protein catabolic process136
GO:0048147negative regulation of fibroblast proliferation124
GO:0010484H3 histone acetyltransferase activity13
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I677
GO:0046686response to cadmium ion122
GO:0072757cellular response to camptothecin13
GO:1901385regulation of voltage-gated calcium channel activity13
GO:0045132meiotic chromosome segregation13
GO:0005929cilium284
GO:0003951NAD+ kinase activity115
GO:0006333chromatin assembly or disassembly16
GO:0005643nuclear pore159
GO:0005791rough endoplasmic reticulum137
GO:0006891intra-Golgi vesicle-mediated transport317
GO:0045879negative regulation of smoothened signaling pathway123
GO:0004673protein histidine kinase activity11
GO:0003674molecular_function1524
GO:0043967histone H4 acetylation228
GO:0006511ubiquitin-dependent protein catabolic process3127
GO:0005798Golgi-associated vesicle110
GO:0033290eukaryotic 48S preinitiation complex113
GO:0071732cellular response to nitric oxide19
GO:0016197endosomal transport358
GO:0002224toll-like receptor signaling pathway5109
GO:0007254JNK cascade351
GO:0006222UMP biosynthetic process14
GO:0005080protein kinase C binding144
GO:0071008U2-type post-mRNA release spliceosomal complex13
GO:0070527platelet aggregation138
GO:0007265Ras protein signal transduction375
GO:0034146toll-like receptor 5 signaling pathway565
GO:0006879cellular iron ion homeostasis257
GO:0072384organelle transport along microtubule24
GO:0045859regulation of protein kinase activity126
GO:0003896DNA primase activity24
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway571
GO:0071222cellular response to lipopolysaccharide481
GO:0005838proteasome regulatory particle312
GO:003446390S preribosome assembly11
GO:0044205'de novo' UMP biosynthetic process13
GO:0007015actin filament organization140
GO:0006959humoral immune response152
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle13
GO:0050681androgen receptor binding238
GO:0005515protein binding876127
GO:0051017actin filament bundle assembly123
GO:0000777condensed chromosome kinetochore168
GO:0007411axon guidance3327
GO:0006936muscle contraction188
GO:0035912dorsal aorta morphogenesis15
GO:0001515opioid peptide activity15
GO:0030141secretory granule267
GO:0070830tight junction assembly133
GO:0017134fibroblast growth factor binding219
GO:0000724double-strand break repair via homologous recombination257
GO:0005689U12-type spliceosomal complex221
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle874
GO:0051897positive regulation of protein kinase B signaling175
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle870
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway264
GO:0034142toll-like receptor 4 signaling pathway596
GO:0045453bone resorption119
GO:0045505dynein intermediate chain binding13
GO:0009411response to UV245
GO:0019894kinesin binding128
GO:0005200structural constituent of cytoskeleton693
GO:0006446regulation of translational initiation236
GO:0008306associative learning117
GO:0070374positive regulation of ERK1 and ERK2 cascade1110
GO:0050658RNA transport17
GO:0032427GBD domain binding11
GO:0007258JUN phosphorylation14
GO:0021766hippocampus development339
GO:0005085guanyl-nucleotide exchange factor activity174
GO:0031424keratinization127
GO:0005737cytoplasm653976
GO:0006289nucleotide-excision repair169
GO:0001892embryonic placenta development123
GO:0006914autophagy177
GO:0044346fibroblast apoptotic process12
GO:0006006glucose metabolic process4119
GO:0021762substantia nigra development246
GO:0031929TOR signaling113
GO:0031577spindle checkpoint14
GO:0006184GTP catabolic process6220
GO:0002181cytoplasmic translation26
GO:0016607nuclear speck2175
GO:0031584activation of phospholipase D activity15
GO:0090263positive regulation of canonical Wnt signaling pathway151
GO:0003924GTPase activity6203
GO:0009306protein secretion221
GO:0005743mitochondrial inner membrane1300
GO:0016055Wnt signaling pathway3141
GO:0030518intracellular steroid hormone receptor signaling pathway114
GO:0008150biological_process3459
GO:0005840ribosome1059
GO:0000287magnesium ion binding2174
GO:0007077mitotic nuclear envelope disassembly137
GO:0000278mitotic cell cycle16398
GO:0072429response to intra-S DNA damage checkpoint signaling14
GO:0004550nucleoside diphosphate kinase activity115
GO:0008202steroid metabolic process152
GO:0051683establishment of Golgi localization23
GO:0031532actin cytoskeleton reorganization242
GO:0000165MAPK cascade272
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle665
GO:0016071mRNA metabolic process29223
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process115
GO:0042307positive regulation of protein import into nucleus215
GO:0043589skin morphogenesis18
GO:0030049muscle filament sliding238
GO:0001829trophectodermal cell differentiation117
GO:0034220ion transmembrane transport2167
GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation14
GO:0061512protein localization to cilium17
GO:0050728negative regulation of inflammatory response260
GO:0046983protein dimerization activity3131
GO:0097110scaffold protein binding134
GO:0007080mitotic metaphase plate congression113
GO:0090096positive regulation of metanephric cap mesenchymal cell proliferation11
GO:0007173epidermal growth factor receptor signaling pathway5191
GO:0051988regulation of attachment of spindle microtubules to kinetochore17
GO:0006669sphinganine-1-phosphate biosynthetic process11
GO:0042493response to drug2288
GO:0043524negative regulation of neuron apoptotic process1119
GO:0004708MAP kinase kinase activity113
GO:0034613cellular protein localization244
GO:0022605oogenesis stage11
GO:0009404toxin metabolic process15
GO:0006950response to stress148
GO:0006414translational elongation2293
GO:0001961positive regulation of cytokine-mediated signaling pathway17
GO:0007179transforming growth factor beta receptor signaling pathway4130
GO:0000028ribosomal small subunit assembly37
GO:0005829cytosol742562
GO:0000737DNA catabolic process, endonucleolytic139
GO:0034138toll-like receptor 3 signaling pathway580
GO:0030971receptor tyrosine kinase binding133
GO:0007289spermatid nucleus differentiation18
GO:0042542response to hydrogen peroxide140
GO:0000775chromosome, centromeric region152
GO:0006996organelle organization110
GO:0005802trans-Golgi network2116
GO:0033206meiotic cytokinesis12
GO:0048589developmental growth126
GO:0017022myosin binding218
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis477
GO:0000245spliceosomal complex assembly121
GO:0001578microtubule bundle formation120
GO:0007528neuromuscular junction development132
GO:0045842positive regulation of mitotic metaphase/anaphase transition16
GO:0008286insulin receptor signaling pathway4144
GO:0048011neurotrophin TRK receptor signaling pathway5273
GO:0007067mitotic nuclear division7231
GO:0008654phospholipid biosynthetic process115
GO:0007092activation of mitotic anaphase-promoting complex activity12
GO:0031996thioesterase binding114
GO:0030968endoplasmic reticulum unfolded protein response181
GO:0060333interferon-gamma-mediated signaling pathway164
GO:0014075response to amine19
GO:0033137negative regulation of peptidyl-serine phosphorylation116
GO:0034101erythrocyte homeostasis17
GO:0005885Arp2/3 protein complex17
GO:0008356asymmetric cell division13
GO:0001764neuron migration296
GO:0005789endoplasmic reticulum membrane3636
GO:0006310DNA recombination267
GO:0002176male germ cell proliferation12
GO:0019395fatty acid oxidation111
GO:0070937CRD-mediated mRNA stability complex16
GO:0043004cytoplasmic sequestering of CFTR protein11
GO:0005875microtubule associated complex128
GO:0060971embryonic heart tube left/right pattern formation15
GO:0004103choline kinase activity12
GO:0005576extracellular region41049
GO:0060397JAK-STAT cascade involved in growth hormone signaling pathway123
GO:0018106peptidyl-histidine phosphorylation11
GO:0005575cellular_component2322
GO:0000722telomere maintenance via recombination226
GO:0031435mitogen-activated protein kinase kinase kinase binding122
GO:0042803protein homodimerization activity4617
GO:0004842ubiquitin-protein transferase activity3256
GO:0001667ameboidal-type cell migration16
GO:2000811negative regulation of anoikis116
GO:0003779actin binding3275
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor13
GO:0060338regulation of type I interferon-mediated signaling pathway125
GO:0010507negative regulation of autophagy118
GO:0051082unfolded protein binding195
GO:0009615response to virus4132
GO:0005096GTPase activator activity3108
GO:0050779RNA destabilization13
GO:0032479regulation of type I interferon production213
GO:0031490chromatin DNA binding139
GO:0043968histone H2A acetylation112
GO:0002162dystroglycan binding17
GO:0070182DNA polymerase binding18
GO:0000932cytoplasmic mRNA processing body156
GO:0035092sperm chromatin condensation14
GO:0005869dynactin complex18
GO:0001658branching involved in ureteric bud morphogenesis143
GO:0031084BLOC-2 complex13
GO:0045124regulation of bone resorption18
GO:0001502cartilage condensation120
GO:0003700sequence-specific DNA binding transcription factor activity9748
GO:0001047core promoter binding146
GO:0048822enucleate erythrocyte development12
GO:0035264multicellular organism growth170
GO:0033523histone H2B ubiquitination18
GO:0061003positive regulation of dendritic spine morphogenesis18
GO:0043623cellular protein complex assembly116
GO:0035335peptidyl-tyrosine dephosphorylation294
GO:0006355regulation of transcription, DNA-templated101104
GO:0035924cellular response to vascular endothelial growth factor stimulus120
GO:0072422signal transduction involved in DNA damage checkpoint12
GO:0000070mitotic sister chromatid segregation119
GO:0019900kinase binding354
GO:0017049GTP-Rho binding110
GO:0015992proton transport132
GO:0022407regulation of cell-cell adhesion110
GO:0031648protein destabilization121
GO:0051219phosphoprotein binding432
GO:0002020protease binding174
GO:0035518histone H2A monoubiquitination211
GO:0000187activation of MAPK activity390
GO:0001076RNA polymerase II transcription factor binding transcription factor activity110
GO:0005813centrosome9339
GO:0006890retrograde vesicle-mediated transport, Golgi to ER625
GO:0048026positive regulation of mRNA splicing, via spliceosome16
GO:0009986cell surface1422
GO:0042692muscle cell differentiation234
GO:0010467gene expression36669
GO:0003713transcription coactivator activity6239
GO:0033561regulation of water loss via skin13
GO:0000794condensed nuclear chromosome124
GO:0034166toll-like receptor 10 signaling pathway565
GO:0051881regulation of mitochondrial membrane potential121
GO:0007049cell cycle4177
GO:0042981regulation of apoptotic process7151
GO:0006646phosphatidylethanolamine biosynthetic process113
GO:0051015actin filament binding197
GO:0019903protein phosphatase binding163
GO:0000974Prp19 complex16
GO:0007601visual perception1168
GO:0007166cell surface receptor signaling pathway1149
GO:0046854phosphatidylinositol phosphorylation128
GO:0008584male gonad development177
GO:0043196varicosity16
GO:0070062extracellular vesicular exosome512516
GO:0016605PML body292
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway225
GO:0030036actin cytoskeleton organization3129
GO:0030148sphingolipid biosynthetic process126
GO:0005175CD27 receptor binding11
GO:0014069postsynaptic density3106
GO:0004197cysteine-type endopeptidase activity252
GO:0005662DNA replication factor A complex113
GO:0035305negative regulation of dephosphorylation12
GO:0042995cell projection163
GO:0006657CDP-choline pathway17
GO:0001103RNA polymerase II repressing transcription factor binding127
GO:0071398cellular response to fatty acid213
GO:0036152phosphatidylethanolamine acyl-chain remodeling118
GO:0048812neuron projection morphogenesis133
GO:0043044ATP-dependent chromatin remodeling123
GO:0005739mitochondrion101046
GO:0048041focal adhesion assembly123
GO:0000902cell morphogenesis151
GO:0001672regulation of chromatin assembly or disassembly12
GO:0005915zonula adherens19
GO:0050790regulation of catalytic activity169
GO:2000114regulation of establishment of cell polarity115
GO:0072661protein targeting to plasma membrane119
GO:0038066p38MAPK cascade11
GO:0051260protein homooligomerization2150
GO:0032956regulation of actin cytoskeleton organization130
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway336
GO:0036150phosphatidylserine acyl-chain remodeling112
GO:0031063regulation of histone deacetylation14
GO:0097372NAD-dependent histone deacetylase activity (H3-K18 specific)112
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator130
GO:0045740positive regulation of DNA replication138
GO:0045296cadherin binding125
GO:0018107peptidyl-threonine phosphorylation137
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity226
GO:0010735positive regulation of transcription via serum response element binding14
GO:0005547phosphatidylinositol-3,4,5-trisphosphate binding130
GO:0030900forebrain development151
GO:0032880regulation of protein localization137
GO:0005968Rab-protein geranylgeranyltransferase complex14
GO:0035791platelet-derived growth factor receptor-beta signaling pathway12
GO:0045656negative regulation of monocyte differentiation14
GO:0009966regulation of signal transduction117
GO:0050885neuromuscular process controlling balance141
GO:0030957Tat protein binding16
GO:0071456cellular response to hypoxia398
GO:0030331estrogen receptor binding127
GO:0042470melanosome292
GO:0016192vesicle-mediated transport1122
GO:0051602response to electrical stimulus124
GO:0034663endoplasmic reticulum chaperone complex13
GO:0030948negative regulation of vascular endothelial growth factor receptor signaling pathway17
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle122
GO:0017145stem cell division17
GO:0045071negative regulation of viral genome replication234
GO:0045202synapse1140
GO:0048705skeletal system morphogenesis125
GO:0033387putrescine biosynthetic process from ornithine11
GO:1900087positive regulation of G1/S transition of mitotic cell cycle113
GO:0004402histone acetyltransferase activity143
GO:0048565digestive tract development127
GO:0002027regulation of heart rate230
GO:0001731formation of translation preinitiation complex117
GO:0043473pigmentation220
GO:1902305regulation of sodium ion transmembrane transport17
GO:0007062sister chromatid cohesion113
GO:0040018positive regulation of multicellular organism growth130
GO:0006887exocytosis169
GO:0045666positive regulation of neuron differentiation168
GO:0048365Rac GTPase binding129
GO:0043025neuronal cell body5254
GO:0071560cellular response to transforming growth factor beta stimulus136
GO:0090090negative regulation of canonical Wnt signaling pathway388
GO:0000055ribosomal large subunit export from nucleus14
GO:0005178integrin binding197
GO:0005887integral component of plasma membrane2961
GO:0060314regulation of ryanodine-sensitive calcium-release channel activity113
GO:0060266negative regulation of respiratory burst involved in inflammatory response13
GO:0005925focal adhesion23370
GO:0047497mitochondrion transport along microtubule19
GO:0051660establishment of centrosome localization11
GO:0090135actin filament branching12
GO:0005764lysosome2182
GO:0000790nuclear chromatin2133
GO:0035189Rb-E2F complex14
GO:0007519skeletal muscle tissue development141
GO:0033625positive regulation of integrin activation14
GO:0055003cardiac myofibril assembly112
GO:0034088maintenance of mitotic sister chromatid cohesion14
GO:0030866cortical actin cytoskeleton organization119
GO:0007094mitotic spindle assembly checkpoint131
GO:0071204histone pre-mRNA 3'end processing complex16
GO:0000730DNA recombinase assembly15
GO:0030424axon4172
GO:0016070RNA metabolic process29247
GO:0006397mRNA processing3169
GO:0032319regulation of Rho GTPase activity19
GO:0030234enzyme regulator activity213
GO:0043142single-stranded DNA-dependent ATPase activity13
GO:0007568aging2123
GO:0000930gamma-tubulin complex17
GO:0032201telomere maintenance via semi-conservative replication222
GO:0090316positive regulation of intracellular protein transport118
GO:0060444branching involved in mammary gland duct morphogenesis113
GO:0016874ligase activity2224
GO:0030863cortical cytoskeleton122
GO:0034975protein folding in endoplasmic reticulum11
GO:0050896response to stimulus144
GO:0000118histone deacetylase complex128
GO:0032465regulation of cytokinesis114
GO:0021540corpus callosum morphogenesis13
GO:0009991response to extracellular stimulus14
GO:0005815microtubule organizing center4110
GO:0043393regulation of protein binding220
GO:0015630microtubule cytoskeleton4112
GO:0051044positive regulation of membrane protein ectodomain proteolysis115
GO:0030687preribosome, large subunit precursor13
GO:0001556oocyte maturation117
GO:0060047heart contraction110
GO:0055086nucleobase-containing small molecule metabolic process273
GO:0016482cytoplasmic transport15
GO:0007052mitotic spindle organization122
GO:0005525GTP binding6328
GO:0046016positive regulation of transcription by glucose11
GO:0032321positive regulation of Rho GTPase activity188
GO:0010494cytoplasmic stress granule230
GO:0030674protein binding, bridging152
GO:0046628positive regulation of insulin receptor signaling pathway19
GO:0003993acid phosphatase activity18
GO:0043539protein serine/threonine kinase activator activity114
GO:0010831positive regulation of myotube differentiation18
GO:0004143diacylglycerol kinase activity113
GO:0000281mitotic cytokinesis121
GO:0021819layer formation in cerebral cortex111
GO:0046834lipid phosphorylation15
GO:0050775positive regulation of dendrite morphogenesis116
GO:0035855megakaryocyte development113
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis12
GO:2000379positive regulation of reactive oxygen species metabolic process124
GO:0032495response to muramyl dipeptide19
GO:0042626ATPase activity, coupled to transmembrane movement of substances128
GO:0005031tumor necrosis factor-activated receptor activity19
GO:0007126meiotic nuclear division117
GO:0009725response to hormone135
GO:0050679positive regulation of epithelial cell proliferation254
GO:0030425dendrite3240
GO:0035371microtubule plus-end114
GO:0045502dynein binding111
GO:0042593glucose homeostasis189
GO:0070555response to interleukin-1131
GO:0032091negative regulation of protein binding133
GO:0045556positive regulation of TRAIL biosynthetic process11
GO:0006094gluconeogenesis145
GO:0030027lamellipodium3130
GO:0043005neuron projection6161
GO:0007160cell-matrix adhesion188
GO:0034332adherens junction organization436
GO:0045177apical part of cell182
GO:00163081-phosphatidylinositol-4-phosphate 5-kinase activity17
GO:0001569patterning of blood vessels134
GO:0010008endosome membrane2157
GO:0042809vitamin D receptor binding115
GO:0007059chromosome segregation364
GO:0006521regulation of cellular amino acid metabolic process550
GO:0051087chaperone binding159
GO:1900026positive regulation of substrate adhesion-dependent cell spreading123
GO:2000134negative regulation of G1/S transition of mitotic cell cycle120
GO:0007405neuroblast proliferation116
GO:0090287regulation of cellular response to growth factor stimulus11
GO:0005975carbohydrate metabolic process3274
GO:0006611protein export from nucleus125
GO:0051106positive regulation of DNA ligation13
GO:0016568chromatin modification299
GO:0008135translation factor activity, nucleic acid binding424
GO:003068690S preribosome14
GO:0045931positive regulation of mitotic cell cycle226
GO:0061136regulation of proteasomal protein catabolic process112
GO:0004674protein serine/threonine kinase activity6312
GO:0030490maturation of SSU-rRNA24
GO:0043021ribonucleoprotein complex binding121
GO:0005881cytoplasmic microtubule141
GO:0006259DNA metabolic process119
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway571
GO:0051156glucose 6-phosphate metabolic process18
GO:0016301kinase activity237
GO:0070934CRD-mediated mRNA stabilization15
GO:0045121membrane raft3161
GO:00709353'-UTR-mediated mRNA stabilization112
GO:0001822kidney development279
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process119
GO:0051781positive regulation of cell division139
GO:0032720negative regulation of tumor necrosis factor production127
GO:0032496response to lipopolysaccharide1122
GO:0044458motile cilium assembly16
GO:0005761mitochondrial ribosome124
GO:0033033negative regulation of myeloid cell apoptotic process15
GO:0070064proline-rich region binding118
GO:0001618virus receptor activity130
GO:0031572G2 DNA damage checkpoint119
GO:0014911positive regulation of smooth muscle cell migration116
GO:0086005ventricular cardiac muscle cell action potential117
GO:0045618positive regulation of keratinocyte differentiation110
GO:0046185aldehyde catabolic process12
GO:0005793endoplasmic reticulum-Golgi intermediate compartment157
GO:0001726ruffle182
GO:0044325ion channel binding377
GO:0010447response to acidic pH17
GO:0006644phospholipid metabolic process3137
GO:0000235astral microtubule11
GO:0006955immune response2305
GO:0007268synaptic transmission1353
GO:0002309T cell proliferation involved in immune response16
GO:0071393cellular response to progesterone stimulus11
GO:0016020membrane481746
GO:0010256endomembrane system organization12
GO:0019005SCF ubiquitin ligase complex129
GO:0008026ATP-dependent helicase activity239
GO:0006654phosphatidic acid biosynthetic process125
GO:0048666neuron development135
GO:0045216cell-cell junction organization259
GO:0030071regulation of mitotic metaphase/anaphase transition15
GO:0004347glucose-6-phosphate isomerase activity11
GO:0016337single organismal cell-cell adhesion292
GO:0000077DNA damage checkpoint128
GO:0051262protein tetramerization130
GO:0006665sphingolipid metabolic process168
GO:0007000nucleolus organization24
GO:0045648positive regulation of erythrocyte differentiation121
GO:2001022positive regulation of response to DNA damage stimulus17
GO:0016281eukaryotic translation initiation factor 4F complex19
GO:0043293apoptosome13
GO:0048477oogenesis115
GO:0030666endocytic vesicle membrane254
GO:0034097response to cytokine150
GO:0010880regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum117
GO:0016328lateral plasma membrane346
GO:0009301snRNA transcription14
GO:0003724RNA helicase activity110
GO:0006351transcription, DNA-templated171585
GO:0030131clathrin adaptor complex115
GO:0017166vinculin binding111
GO:0003161cardiac conduction system development13
GO:0042551neuron maturation111
GO:0005615extracellular space31010
GO:0016477cell migration1131
GO:0071459protein localization to chromosome, centromeric region13
GO:0071260cellular response to mechanical stimulus366
GO:0047485protein N-terminus binding186
GO:0040008regulation of growth151
GO:0009142nucleoside triphosphate biosynthetic process17
GO:0006302double-strand break repair262
GO:0006112energy reserve metabolic process299
GO:0045651positive regulation of macrophage differentiation111
GO:0060307regulation of ventricular cardiac muscle cell membrane repolarization111
GO:0070301cellular response to hydrogen peroxide141
GO:0007369gastrulation121
GO:0045862positive regulation of proteolysis121
GO:0006468protein phosphorylation6467
GO:0007257activation of JUN kinase activity136
GO:0006886intracellular protein transport6173
GO:0032040small-subunit processome110
GO:0010669epithelial structure maintenance14
GO:0008047enzyme activator activity139
GO:0015035protein disulfide oxidoreductase activity121
GO:0051146striated muscle cell differentiation212
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription140
GO:0042274ribosomal small subunit biogenesis612
GO:0010629negative regulation of gene expression280
GO:0031295T cell costimulation367
GO:0007050cell cycle arrest2126
GO:0007616long-term memory127
GO:0004704NF-kappaB-inducing kinase activity16
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia226
GO:0043488regulation of mRNA stability113
GO:0030097hemopoiesis158
GO:0007611learning or memory234
GO:0004407histone deacetylase activity116
GO:0008631intrinsic apoptotic signaling pathway in response to oxidative stress118
GO:0032463negative regulation of protein homooligomerization14
GO:0042384cilium assembly290
GO:0046872metal ion binding141465
GO:0044297cell body146
GO:0051902negative regulation of mitochondrial depolarization14
GO:0031519PcG protein complex125
GO:0005083small GTPase regulator activity127
GO:0006200ATP catabolic process4303
GO:0001948glycoprotein binding250
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator12
GO:0010457centriole-centriole cohesion16
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest665
GO:2000573positive regulation of DNA biosynthetic process211
GO:0036148phosphatidylglycerol acyl-chain remodeling115
GO:0032481positive regulation of type I interferon production361
GO:0007596blood coagulation5464
GO:0006096glycolytic process139
GO:0060055angiogenesis involved in wound healing17
GO:0018344protein geranylgeranylation16
GO:0002762negative regulation of myeloid leukocyte differentiation12
GO:0035088establishment or maintenance of apical/basal cell polarity15
GO:0050998nitric-oxide synthase binding316
GO:0021987cerebral cortex development142
GO:0032204regulation of telomere maintenance13
GO:0051154negative regulation of striated muscle cell differentiation13
GO:0060020Bergmann glial cell differentiation14
GO:0051385response to mineralocorticoid15
GO:0042802identical protein binding4491
GO:0030175filopodium253
GO:0071333cellular response to glucose stimulus235
GO:0010800positive regulation of peptidyl-threonine phosphorylation118
GO:0007155cell adhesion3384
GO:0010997anaphase-promoting complex binding13
GO:0070848response to growth factor114
GO:0051347positive regulation of transferase activity16
GO:0097284hepatocyte apoptotic process19
GO:0045893positive regulation of transcription, DNA-templated8487
GO:0010225response to UV-C110
GO:0039702viral budding via host ESCRT complex18
GO:0045773positive regulation of axon extension118
GO:0042254ribosome biogenesis130
GO:0050684regulation of mRNA processing15
GO:0007264small GTPase mediated signal transduction7290
GO:0051272positive regulation of cellular component movement111
GO:0033291eukaryotic 80S initiation complex11
GO:0033572transferrin transport132
GO:0070307lens fiber cell development110
GO:0005516calmodulin binding3162
GO:1900222negative regulation of beta-amyloid clearance13
GO:0004709MAP kinase kinase kinase activity118
GO:0004725protein tyrosine phosphatase activity180
GO:0001701in utero embryonic development2210
GO:0006271DNA strand elongation involved in DNA replication231
GO:0071364cellular response to epidermal growth factor stimulus121
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription162
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II392
GO:0006312mitotic recombination15
GO:0000086G2/M transition of mitotic cell cycle6137
GO:0005826actomyosin contractile ring15
GO:0043149stress fiber assembly212
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process263
GO:0031062positive regulation of histone methylation14
GO:0005102receptor binding2268
GO:0006661phosphatidylinositol biosynthetic process154
GO:0045454cell redox homeostasis152
GO:0044267cellular protein metabolic process29495
GO:0060334regulation of interferon-gamma-mediated signaling pathway116
GO:0046969NAD-dependent histone deacetylase activity (H3-K9 specific)113
GO:0048205COPI coating of Golgi vesicle613
GO:0005856cytoskeleton6311
GO:0000910cytokinesis251
GO:0048667cell morphogenesis involved in neuron differentiation15
GO:0070373negative regulation of ERK1 and ERK2 cascade131
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent673
GO:0038061NIK/NF-kappaB signaling19
GO:0060684epithelial-mesenchymal cell signaling14
GO:0043547positive regulation of GTPase activity4190
GO:0004386helicase activity156
GO:0005777peroxisome190
GO:0070851growth factor receptor binding14
GO:0016829lyase activity115
GO:0090230regulation of centromere complex assembly11
GO:0097443sorting endosome13
GO:1902188positive regulation of viral release from host cell15
GO:0002756MyD88-independent toll-like receptor signaling pathway578
GO:0030838positive regulation of actin filament polymerization136
GO:0030155regulation of cell adhesion142
GO:0072562blood microparticle1116
GO:0043406positive regulation of MAP kinase activity147
GO:0017050D-erythro-sphingosine kinase activity12
GO:0005814centriole180
GO:0006928cellular component movement492
GO:0000723telomere maintenance259
GO:0043550regulation of lipid kinase activity14
GO:0005100Rho GTPase activator activity124
GO:0046966thyroid hormone receptor binding126
GO:0006268DNA unwinding involved in DNA replication110
GO:0031954positive regulation of protein autophosphorylation118
GO:0061077chaperone-mediated protein folding131
GO:0046875ephrin receptor binding230
GO:0000940condensed chromosome outer kinetochore19
GO:0009898cytoplasmic side of plasma membrane142
GO:0004871signal transducer activity1216
GO:2001238positive regulation of extrinsic apoptotic signaling pathway127
GO:0016013syntrophin complex24
GO:0006595polyamine metabolic process114
GO:0006457protein folding3149
GO:0000793condensed chromosome221
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding4168
GO:0003729mRNA binding373
GO:2001243negative regulation of intrinsic apoptotic signaling pathway122
GO:0070491repressing transcription factor binding130
GO:0046134pyrimidine nucleoside biosynthetic process16
GO:0017016Ras GTPase binding114
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity119
GO:0014819regulation of skeletal muscle contraction12
GO:0000075cell cycle checkpoint19
GO:0002062chondrocyte differentiation132
GO:0071479cellular response to ionizing radiation225
GO:0001833inner cell mass cell proliferation113
GO:0044233ER-mitochondrion membrane contact site15
GO:0006412translation29235
GO:0043536positive regulation of blood vessel endothelial cell migration117
GO:0002040sprouting angiogenesis123
GO:0006183GTP biosynthetic process18
GO:0010468regulation of gene expression172
GO:0030178negative regulation of Wnt signaling pathway136
GO:0051298centrosome duplication114
GO:0030216keratinocyte differentiation147
GO:0000780condensed nuclear chromosome, centromeric region18
GO:0005099Ras GTPase activator activity116
GO:0045727positive regulation of translation146
GO:1902202regulation of hepatocyte growth factor receptor signaling pathway12
GO:0030521androgen receptor signaling pathway341
GO:0033574response to testosterone122
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity193
GO:0006633fatty acid biosynthetic process137
GO:0016491oxidoreductase activity165
GO:0043231intracellular membrane-bounded organelle3332
GO:0086001cardiac muscle cell action potential12
GO:0043034costamere121
GO:0045214sarcomere organization126
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay153
GO:0034605cellular response to heat129
GO:1990264peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity11
GO:0048554positive regulation of metalloenzyme activity16
GO:0001501skeletal system development1123
GO:0031492nucleosomal DNA binding128
GO:0090231regulation of spindle checkpoint14
GO:0034329cell junction assembly271
GO:0005874microtubule3258
GO:0035690cellular response to drug350
GO:0035666TRIF-dependent toll-like receptor signaling pathway576
GO:0032041NAD-dependent histone deacetylase activity (H3-K14 specific)112
GO:0019068virion assembly217
GO:0005086ARF guanyl-nucleotide exchange factor activity118
GO:0036057slit diaphragm18
GO:0015949nucleobase-containing small molecule interconversion118
GO:0043015gamma-tubulin binding218
GO:0048029monosaccharide binding16
GO:0016887ATPase activity1144
GO:0072686mitotic spindle129
GO:0030126COPI vesicle coat613
GO:0022624proteasome accessory complex417
GO:0006241CTP biosynthetic process19
GO:0021895cerebral cortex neuron differentiation19
GO:0045987positive regulation of smooth muscle contraction115
GO:0003684damaged DNA binding251
GO:0051403stress-activated MAPK cascade454
GO:0008060ARF GTPase activator activity123
GO:0019082viral protein processing212
GO:0008420CTD phosphatase activity15
GO:0043497regulation of protein heterodimerization activity17
GO:0012505endomembrane system157
GO:0050792regulation of viral process16
GO:0006357regulation of transcription from RNA polymerase II promoter2275
GO:0005819spindle4114
GO:0015629actin cytoskeleton3183
GO:0045860positive regulation of protein kinase activity145
GO:0005634nucleus664828
GO:0048488synaptic vesicle endocytosis114
GO:0006417regulation of translation463
GO:0031016pancreas development122
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3148
GO:0042535positive regulation of tumor necrosis factor biosynthetic process110
GO:0031667response to nutrient levels119
GO:0070932histone H3 deacetylation121
GO:0008233peptidase activity155
GO:0046847filopodium assembly121
GO:0048027mRNA 5'-UTR binding17
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity161
GO:0045445myoblast differentiation115
GO:0004672protein kinase activity4178
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway243
GO:0010485H4 histone acetyltransferase activity16
GO:0003735structural constituent of ribosome24141
GO:0042273ribosomal large subunit biogenesis113
GO:0007097nuclear migration27
GO:0005765lysosomal membrane2218
GO:0035267NuA4 histone acetyltransferase complex214
GO:0070888E-box binding132
GO:0048146positive regulation of fibroblast proliferation144
GO:0008608attachment of spindle microtubules to kinetochore17
GO:0046970NAD-dependent histone deacetylase activity (H4-K16 specific)112
GO:0007091metaphase/anaphase transition of mitotic cell cycle17
GO:0005978glycogen biosynthetic process226
GO:0045663positive regulation of myoblast differentiation111
GO:0033138positive regulation of peptidyl-serine phosphorylation161
GO:0031465Cul4B-RING E3 ubiquitin ligase complex15
GO:0043114regulation of vascular permeability18
GO:0030496midbody4109
GO:0048821erythrocyte development215
GO:0005730nucleolus361684
GO:0043086negative regulation of catalytic activity174
GO:0006935chemotaxis1108
GO:0031527filopodium membrane117
GO:0005886plasma membrane242834
GO:0000226microtubule cytoskeleton organization155
GO:0051591response to cAMP145
GO:0042147retrograde transport, endosome to Golgi142
GO:0031274positive regulation of pseudopodium assembly210
GO:0007030Golgi organization350
GO:0071480cellular response to gamma radiation114
GO:0005902microvillus142
GO:0071338positive regulation of hair follicle cell proliferation12
GO:0005509calcium ion binding4589
GO:0035145exon-exon junction complex119
GO:0002755MyD88-dependent toll-like receptor signaling pathway580
GO:0048255mRNA stabilization112
GO:0005852eukaryotic translation initiation factor 3 complex115
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator114
GO:0005790smooth endoplasmic reticulum122
GO:0097190apoptotic signaling pathway3116
GO:0019901protein kinase binding9320
GO:0051297centrosome organization223
GO:0003334keratinocyte development17
GO:0046627negative regulation of insulin receptor signaling pathway125
GO:0009791post-embryonic development175
GO:0005911cell-cell junction2142
GO:0030892mitotic cohesin complex12
GO:0000209protein polyubiquitination7116
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway126
GO:0030140trans-Golgi network transport vesicle112
GO:0019215intermediate filament binding16
GO:0051081nuclear envelope disassembly12
GO:0032320positive regulation of Ras GTPase activity132
GO:0006614SRP-dependent cotranslational protein targeting to membrane22104
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand115
GO:0042176regulation of protein catabolic process416
GO:0061647histone H3-K9 modification113
GO:0070914UV-damage excision repair17
GO:0005788endoplasmic reticulum lumen2157
GO:0030100regulation of endocytosis118
GO:0045785positive regulation of cell adhesion141
GO:0016567protein ubiquitination3299
GO:0007186G-protein coupled receptor signaling pathway1367
GO:0016592mediator complex235
GO:0016363nuclear matrix492
GO:0042169SH2 domain binding130
GO:0048664neuron fate determination14
GO:0070545PeBoW complex13
GO:0005522profilin binding18
GO:0031647regulation of protein stability130
GO:0045109intermediate filament organization111
GO:0060065uterus development111
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity159
GO:0015935small ribosomal subunit917
GO:0010569regulation of double-strand break repair via homologous recombination111
GO:0003743translation initiation factor activity549
GO:0043249erythrocyte maturation112
GO:0035091phosphatidylinositol binding161
GO:0006915apoptotic process9571
GO:0010761fibroblast migration18
GO:0001106RNA polymerase II transcription corepressor activity122
GO:0006413translational initiation27131
GO:0022028tangential migration from the subventricular zone to the olfactory bulb13
GO:0060070canonical Wnt signaling pathway275
GO:0030198extracellular matrix organization1295
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)13
GO:0048024regulation of mRNA splicing, via spliceosome26
GO:0042393histone binding171
GO:0006670sphingosine metabolic process13
GO:0005759mitochondrial matrix1233
GO:0033077T cell differentiation in thymus133
GO:0043043peptide biosynthetic process15
GO:0009636response to toxic substance166
GO:0004726non-membrane spanning protein tyrosine phosphatase activity17
GO:0034501protein localization to kinetochore18
GO:0030220platelet formation116
GO:0070688MLL5-L complex18
GO:0004707MAP kinase activity111
GO:0010907positive regulation of glucose metabolic process17
GO:0033503HULC complex14
GO:0007517muscle organ development183
GO:0046474glycerophospholipid biosynthetic process276
GO:0006325chromatin organization2123
GO:0042383sarcolemma271
GO:0050715positive regulation of cytokine secretion125
GO:0005198structural molecule activity5159
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)12
GO:0034185apolipoprotein binding114
GO:0010332response to gamma radiation229
GO:0051653spindle localization13
GO:0046677response to antibiotic131
GO:0004713protein tyrosine kinase activity182
GO:0048193Golgi vesicle transport17
GO:0046326positive regulation of glucose import125
GO:0017080sodium channel regulator activity122
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity13
GO:0060048cardiac muscle contraction139
GO:0051489regulation of filopodium assembly18
GO:0020037heme binding1111
GO:0072583clathrin-mediated endocytosis112
GO:0035914skeletal muscle cell differentiation142
GO:0034641cellular nitrogen compound metabolic process5177
GO:0045070positive regulation of viral genome replication217
GO:0019221cytokine-mediated signaling pathway5230
GO:0010390histone monoubiquitination111
GO:0034067protein localization to Golgi apparatus19
GO:0005635nuclear envelope2116
GO:0000139Golgi membrane7408
GO:0006921cellular component disassembly involved in execution phase of apoptosis147
GO:0008270zinc ion binding71067
GO:0016010dystrophin-associated glycoprotein complex115
GO:0047496vesicle transport along microtubule112
GO:0006281DNA repair5264
GO:0050852T cell receptor signaling pathway288
GO:0033146regulation of intracellular estrogen receptor signaling pathway13
GO:0031023microtubule organizing center organization15
GO:0038095Fc-epsilon receptor signaling pathway3171
GO:0033593BRCA2-MAGE-D1 complex11
GO:0006165nucleoside diphosphate phosphorylation114
GO:0031625ubiquitin protein ligase binding4180
GO:0005850eukaryotic translation initiation factor 2 complex13
GO:0007420brain development3172
GO:0005179hormone activity184
GO:0030544Hsp70 protein binding120
GO:0015031protein transport4357
GO:0016344meiotic chromosome movement towards spindle pole12
GO:0090400stress-induced premature senescence13
GO:0008285negative regulation of cell proliferation3367
GO:0031965nuclear membrane2176
GO:0019003GDP binding148
GO:0005622intracellular1226
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway111
GO:0045682regulation of epidermis development14
GO:0006364rRNA processing896
GO:0031369translation initiation factor binding215
GO:0090303positive regulation of wound healing110
GO:0030157pancreatic juice secretion17
GO:0007219Notch signaling pathway4125
GO:0051056regulation of small GTPase mediated signal transduction3123
GO:0007399nervous system development1245
GO:1903543positive regulation of exosomal secretion112
GO:0007141male meiosis I117
GO:0005524ATP binding191354
GO:0010632regulation of epithelial cell migration12
GO:0001503ossification271
GO:0044281small molecule metabolic process161295
GO:0001707mesoderm formation126
GO:0010881regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion119
GO:0006206pyrimidine nucleobase metabolic process124
GO:0021691cerebellar Purkinje cell layer maturation11
GO:0007569cell aging125
GO:0001895retina homeostasis136
GO:0046716muscle cell cellular homeostasis116
GO:0008585female gonad development115
GO:0006228UTP biosynthetic process19
GO:0033119negative regulation of RNA splicing25
GO:0030837negative regulation of actin filament polymerization19
GO:0043234protein complex9300
GO:0005844polysome225
GO:0043687post-translational protein modification1181
GO:0097191extrinsic apoptotic signaling pathway338
GO:0006338chromatin remodeling268
GO:0030054cell junction4356
GO:0034976response to endoplasmic reticulum stress152
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2151
GO:0014002astrocyte development111
GO:0071541eukaryotic translation initiation factor 3 complex, eIF3m17
GO:0003682chromatin binding4334
GO:0060326cell chemotaxis151
GO:0005095GTPase inhibitor activity114
GO:0045597positive regulation of cell differentiation128
GO:0090136epithelial cell-cell adhesion29
GO:0007565female pregnancy180
GO:0000056ribosomal small subunit export from nucleus23
GO:0007093mitotic cell cycle checkpoint231
GO:0004705JUN kinase activity13
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway18
GO:0001933negative regulation of protein phosphorylation139
GO:0007010cytoskeleton organization196
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding154
GO:0051525NFAT protein binding15
GO:0016042lipid catabolic process252
GO:0030742GTP-dependent protein binding117
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process154
GO:0030165PDZ domain binding195
GO:0007017microtubule-based process228
GO:0045211postsynaptic membrane3177
GO:0045184establishment of protein localization227
GO:0055085transmembrane transport3514
GO:00482573'-flap endonuclease activity12
GO:0000942condensed nuclear chromosome outer kinetochore13
GO:0036149phosphatidylinositol acyl-chain remodeling113
GO:0051276chromosome organization116
GO:0061029eyelid development in camera-type eye110
GO:0031467Cul7-RING ubiquitin ligase complex14
GO:0010976positive regulation of neuron projection development260
GO:0007249I-kappaB kinase/NF-kappaB signaling441
GO:0007605sensory perception of sound1111
GO:0022627cytosolic small ribosomal subunit2139
GO:0033600negative regulation of mammary gland epithelial cell proliferation15
GO:0046330positive regulation of JNK cascade155
GO:0034452dynactin binding16
GO:0051233spindle midzone215
GO:0001675acrosome assembly110
GO:0005762mitochondrial large ribosomal subunit115
GO:0008201heparin binding1127
GO:0008543fibroblast growth factor receptor signaling pathway3159
GO:0043197dendritic spine283
GO:0017137Rab GTPase binding178
GO:1901741positive regulation of myoblast fusion15
GO:0000186activation of MAPKK activity154
GO:0007266Rho protein signal transduction148
GO:0006650glycerophospholipid metabolic process12
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane126
GO:0031334positive regulation of protein complex assembly114
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding175
GO:0072015glomerular visceral epithelial cell development16
GO:0006656phosphatidylcholine biosynthetic process122
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator120
GO:0034349glial cell apoptotic process14
GO:0007595lactation139
GO:0005212structural constituent of eye lens116
GO:0005770late endosome194
GO:0071803positive regulation of podosome assembly15
GO:0031134sister chromatid biorientation12
GO:0000166nucleotide binding2272
GO:0018108peptidyl-tyrosine phosphorylation1133
GO:0004715non-membrane spanning protein tyrosine kinase activity142
GO:0060218hematopoietic stem cell differentiation110
GO:0000785chromatin273
GO:0006415translational termination2287
GO:0001104RNA polymerase II transcription cofactor activity233
GO:0048854brain morphogenesis115
GO:0004984olfactory receptor activity142
GO:0051258protein polymerization127
GO:0006469negative regulation of protein kinase activity165
GO:0042347negative regulation of NF-kappaB import into nucleus19
GO:1902083negative regulation of peptidyl-cysteine S-nitrosylation23
GO:0050680negative regulation of epithelial cell proliferation154
GO:0045059positive thymic T cell selection19
GO:0030675Rac GTPase activator activity116
GO:0005938cell cortex1109
GO:0031410cytoplasmic vesicle1110
GO:0008344adult locomotory behavior247
GO:0007172signal complex assembly18
GO:0097178ruffle assembly16
GO:0006924activation-induced cell death of T cells26
GO:0036151phosphatidylcholine acyl-chain remodeling122
GO:00515394 iron, 4 sulfur cluster binding137
GO:0031663lipopolysaccharide-mediated signaling pathway129
GO:0036464cytoplasmic ribonucleoprotein granule522
GO:0007599hemostasis19
GO:0050911detection of chemical stimulus involved in sensory perception of smell142
GO:0006270DNA replication initiation222
GO:0043515kinetochore binding14
GO:0005884actin filament246
GO:0060265positive regulation of respiratory burst involved in inflammatory response12
GO:0042770signal transduction in response to DNA damage111
GO:0006508proteolysis2410
GO:0031069hair follicle morphogenesis127
GO:0030478actin cap13
GO:0000082G1/S transition of mitotic cell cycle11150
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process13
GO:0016866intramolecular transferase activity11
GO:1901214regulation of neuron death112
GO:0004663Rab geranylgeranyltransferase activity15
GO:0000956nuclear-transcribed mRNA catabolic process110
GO:0090382phagosome maturation138
GO:0031594neuromuscular junction146
GO:0010736serum response element binding12
GO:0004930G-protein coupled receptor activity1193
GO:0002011morphogenesis of an epithelial sheet111
GO:0071277cellular response to calcium ion137
GO:0051701interaction with host134
GO:0031175neuron projection development275
GO:0003117regulation of vasoconstriction by circulating norepinephrine11
GO:0005876spindle microtubule134
GO:0034259negative regulation of Rho GTPase activity17
GO:0045732positive regulation of protein catabolic process151
GO:0030532small nuclear ribonucleoprotein complex118
GO:0005794Golgi apparatus8650
GO:0060347heart trabecula formation115
GO:0006888ER to Golgi vesicle-mediated transport155
GO:0046469platelet activating factor metabolic process11