reg-snw-353274

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.583	4.72e-23	8.88e-04	1.38e-03

tai-screen-luciferase-reg-snw-353274 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
[ ZNF445 ]	353274	1	1.629	4.583	3	TF	-	-
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
CUL4B	8450	6	-2.809	5.269	142	TF	-	-
TLK2	11011	8	-4.011	5.672	14	-	-	-
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
YBX1	4904	6	-3.033	5.516	120	TF	-	-
CDC5L	988	15	-3.419	5.672	155	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
CDC5L	988	ZNF445	353274	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	YBX1	4904	pd	<>	reg.ITFP.txt: no annot
YBX1	4904	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
COPA	1314	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot

Related GO terms (97)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0071987	WD40-repeat domain binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0002176	male germ cell proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0001672	regulation of chromatin assembly or disassembly	1.84e-03	1.00e+00	9.083	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.84e-03	1.00e+00	9.083	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0051154	negative regulation of striated muscle cell differentiation	2.76e-03	1.00e+00	8.499	1	1	3
GO:0050658	RNA transport	3.68e-03	1.00e+00	8.083	1	1	4
GO:0030157	pancreatic juice secretion	3.68e-03	1.00e+00	8.083	1	1	4
GO:0044822	poly(A) RNA binding	4.01e-03	1.00e+00	2.441	4	25	799
GO:0000974	Prp19 complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.60e-03	1.00e+00	7.762	1	1	5
GO:0007049	cell cycle	4.69e-03	1.00e+00	4.238	2	2	115
GO:0070937	CRD-mediated mRNA stability complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0070914	UV-damage excision repair	5.52e-03	1.00e+00	7.499	1	1	6
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	2	128
GO:0030126	COPI vesicle coat	6.44e-03	1.00e+00	7.276	1	1	7
GO:0035518	histone H2A monoubiquitination	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005662	DNA replication factor A complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	7.35e-03	1.00e+00	7.083	1	1	8
GO:0001701	in utero embryonic development	8.27e-03	1.00e+00	3.817	2	2	154
GO:0071480	cellular response to gamma radiation	9.18e-03	1.00e+00	6.762	1	1	10
GO:0010507	negative regulation of autophagy	9.18e-03	1.00e+00	6.762	1	1	10
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0007051	spindle organization	9.18e-03	1.00e+00	6.762	1	1	10
GO:0006412	translation	1.09e-02	1.00e+00	3.608	2	13	178
GO:0015935	small ribosomal subunit	1.10e-02	1.00e+00	6.499	1	4	12
GO:0051297	centrosome organization	1.10e-02	1.00e+00	6.499	1	1	12
GO:0048205	COPI coating of Golgi vesicle	1.10e-02	1.00e+00	6.499	1	1	12
GO:0035371	microtubule plus-end	1.19e-02	1.00e+00	6.383	1	1	13
GO:0008135	translation factor activity, nucleic acid binding	1.37e-02	1.00e+00	6.177	1	4	15
GO:0005689	U12-type spliceosomal complex	1.56e-02	1.00e+00	5.996	1	2	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.56e-02	1.00e+00	5.996	1	1	17
GO:0005761	mitochondrial ribosome	1.83e-02	1.00e+00	5.762	1	1	20
GO:0051781	positive regulation of cell division	2.01e-02	1.00e+00	5.624	1	1	22
GO:0003723	RNA binding	2.04e-02	1.00e+00	3.135	2	6	247
GO:0006355	regulation of transcription, DNA-templated	2.35e-02	1.00e+00	2.187	3	9	715
GO:0010494	cytoplasmic stress granule	2.37e-02	1.00e+00	5.383	1	2	26
GO:0045732	positive regulation of protein catabolic process	3.09e-02	1.00e+00	4.996	1	1	34
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	5	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	50	4124
GO:0005882	intermediate filament	3.63e-02	1.00e+00	4.762	1	2	40
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	1	41
GO:0007059	chromosome segregation	4.52e-02	1.00e+00	4.440	1	1	50
GO:0018105	peptidyl-serine phosphorylation	4.61e-02	1.00e+00	4.411	1	2	51
GO:0003677	DNA binding	4.89e-02	1.00e+00	1.781	3	12	947
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	28	1641
GO:0008584	male gonad development	5.13e-02	1.00e+00	4.251	1	1	57
GO:0003697	single-stranded DNA binding	5.13e-02	1.00e+00	4.251	1	3	57
GO:0005179	hormone activity	5.40e-02	1.00e+00	4.177	1	1	60
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	1	61
GO:0000922	spindle pole	6.10e-02	1.00e+00	3.996	1	3	68
GO:0016568	chromatin modification	6.10e-02	1.00e+00	3.996	1	2	68
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	3	82
GO:0003690	double-stranded DNA binding	7.40e-02	1.00e+00	3.708	1	1	83
GO:0006886	intracellular protein transport	7.91e-02	1.00e+00	3.608	1	1	89
GO:0061024	membrane organization	7.91e-02	1.00e+00	3.608	1	3	89
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	1	92
GO:0010467	gene expression	8.35e-02	1.00e+00	2.020	2	17	535
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	3	97
GO:0006413	translational initiation	8.77e-02	1.00e+00	3.454	1	12	99
GO:0016020	membrane	8.94e-02	1.00e+00	1.431	3	25	1207
GO:0005198	structural molecule activity	8.94e-02	1.00e+00	3.425	1	1	101
GO:0005730	nucleolus	9.11e-02	1.00e+00	1.419	3	21	1217
GO:0003735	structural constituent of ribosome	9.61e-02	1.00e+00	3.315	1	8	109
GO:0003700	sequence-specific DNA binding transcription factor activity	9.66e-02	1.00e+00	1.899	2	9	582
GO:0006974	cellular response to DNA damage stimulus	1.06e-01	1.00e+00	3.165	1	2	121
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	2	122
GO:0031965	nuclear membrane	1.14e-01	1.00e+00	3.061	1	2	130
GO:0031625	ubiquitin protein ligase binding	1.20e-01	1.00e+00	2.975	1	2	138
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	5	165
GO:0008380	RNA splicing	1.42e-01	1.00e+00	2.717	1	4	165
GO:0005634	nucleus	1.43e-01	1.00e+00	0.741	5	40	3246
GO:0004674	protein serine/threonine kinase activity	1.68e-01	1.00e+00	2.461	1	3	197
GO:0035556	intracellular signal transduction	1.69e-01	1.00e+00	2.447	1	3	199
GO:0043234	protein complex	1.78e-01	1.00e+00	2.369	1	8	210
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	6	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	1	218
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	39	2633
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	3	252
GO:0046872	metal ion binding	2.10e-01	1.00e+00	1.216	2	10	934
GO:0005829	cytosol	2.18e-01	1.00e+00	0.865	3	33	1787
GO:0006468	protein phosphorylation	2.46e-01	1.00e+00	1.850	1	3	301
GO:0000278	mitotic cell cycle	2.55e-01	1.00e+00	1.789	1	9	314
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	15	1076
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	2	341
GO:0048471	perinuclear region of cytoplasm	2.76e-01	1.00e+00	1.657	1	7	344
GO:0044267	cellular protein metabolic process	2.81e-01	1.00e+00	1.624	1	13	352
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	6	456
GO:0005615	extracellular space	4.63e-01	1.00e+00	0.737	1	2	651
GO:0005654	nucleoplasm	5.71e-01	1.00e+00	0.309	1	16	876
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	10	892
GO:0005886	plasma membrane	8.37e-01	1.00e+00	-0.717	1	13	1784

Tai-Luciferase

reg-snw-353274

Statistics

Genes (9)

Interactions (9)

Related GO terms (97)