reg-snw-52

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.903	9.49e-27	2.11e-04	3.66e-04

tai-screen-luciferase-reg-snw-52 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
PSMD3	5709	3	-3.935	4.903	55	TF	-	Yes
HSF1	3297	8	-4.179	5.027	138	TF	-	Yes
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
[ ACP1 ]	52	1	-2.230	4.903	46	-	-	-
TLK2	11011	8	-4.011	5.672	14	-	-	-
CDC5L	988	15	-3.419	5.672	155	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
ACP1	52	CDC5L	988	pd	<	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
ACP1	52	MRPS12	6183	pd	<	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot

Related GO terms (118)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0071987	WD40-repeat domain binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0002176	male germ cell proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0001672	regulation of chromatin assembly or disassembly	1.84e-03	1.00e+00	9.083	1	1	2
GO:0090231	regulation of spindle checkpoint	1.84e-03	1.00e+00	9.083	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.84e-03	1.00e+00	9.083	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0007143	female meiotic division	2.76e-03	1.00e+00	8.499	1	1	3
GO:0003993	acid phosphatase activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0050658	RNA transport	3.68e-03	1.00e+00	8.083	1	1	4
GO:0030157	pancreatic juice secretion	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000974	Prp19 complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0060136	embryonic process involved in female pregnancy	5.52e-03	1.00e+00	7.499	1	1	6
GO:0030126	COPI vesicle coat	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005662	DNA replication factor A complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:0071480	cellular response to gamma radiation	9.18e-03	1.00e+00	6.762	1	1	10
GO:0010507	negative regulation of autophagy	9.18e-03	1.00e+00	6.762	1	1	10
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0005838	proteasome regulatory particle	9.18e-03	1.00e+00	6.762	1	2	10
GO:0007051	spindle organization	9.18e-03	1.00e+00	6.762	1	1	10
GO:0030234	enzyme regulator activity	1.01e-02	1.00e+00	6.624	1	1	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0006412	translation	1.09e-02	1.00e+00	3.608	2	13	178
GO:0015935	small ribosomal subunit	1.10e-02	1.00e+00	6.499	1	4	12
GO:0051297	centrosome organization	1.10e-02	1.00e+00	6.499	1	1	12
GO:0048205	COPI coating of Golgi vesicle	1.10e-02	1.00e+00	6.499	1	1	12
GO:0035371	microtubule plus-end	1.19e-02	1.00e+00	6.383	1	1	13
GO:0022624	proteasome accessory complex	1.28e-02	1.00e+00	6.276	1	2	14
GO:0042176	regulation of protein catabolic process	1.28e-02	1.00e+00	6.276	1	3	14
GO:0008135	translation factor activity, nucleic acid binding	1.37e-02	1.00e+00	6.177	1	4	15
GO:0043234	protein complex	1.50e-02	1.00e+00	3.369	2	8	210
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.56e-02	1.00e+00	5.996	1	1	17
GO:0016020	membrane	1.75e-02	1.00e+00	1.846	4	25	1207
GO:0005730	nucleolus	1.80e-02	1.00e+00	1.834	4	21	1217
GO:0001892	embryonic placenta development	1.83e-02	1.00e+00	5.762	1	1	20
GO:0032720	negative regulation of tumor necrosis factor production	1.83e-02	1.00e+00	5.762	1	1	20
GO:0005761	mitochondrial ribosome	1.83e-02	1.00e+00	5.762	1	1	20
GO:0034605	cellular response to heat	2.01e-02	1.00e+00	5.624	1	1	22
GO:0040018	positive regulation of multicellular organism growth	2.01e-02	1.00e+00	5.624	1	1	22
GO:0003682	chromatin binding	2.12e-02	1.00e+00	3.106	2	3	252
GO:0009898	cytoplasmic side of plasma membrane	2.55e-02	1.00e+00	5.276	1	1	28
GO:0006468	protein phosphorylation	2.95e-02	1.00e+00	2.850	2	3	301
GO:0044822	poly(A) RNA binding	3.15e-02	1.00e+00	2.026	3	25	799
GO:0000278	mitotic cell cycle	3.20e-02	1.00e+00	2.789	2	9	314
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	5	37
GO:0006952	defense response	3.36e-02	1.00e+00	4.874	1	1	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	50	4124
GO:0005882	intermediate filament	3.63e-02	1.00e+00	4.762	1	2	40
GO:0006521	regulation of cellular amino acid metabolic process	3.72e-02	1.00e+00	4.726	1	3	41
GO:0000502	proteasome complex	4.25e-02	1.00e+00	4.529	1	2	47
GO:0007059	chromosome segregation	4.52e-02	1.00e+00	4.440	1	1	50
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	4.52e-02	1.00e+00	4.440	1	1	50
GO:0018105	peptidyl-serine phosphorylation	4.61e-02	1.00e+00	4.411	1	2	51
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.69e-02	1.00e+00	4.383	1	3	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.78e-02	1.00e+00	4.356	1	3	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.05e-02	1.00e+00	4.276	1	3	56
GO:0008584	male gonad development	5.13e-02	1.00e+00	4.251	1	1	57
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.13e-02	1.00e+00	4.251	1	3	57
GO:0005179	hormone activity	5.40e-02	1.00e+00	4.177	1	1	60
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.40e-02	1.00e+00	4.177	1	3	60
GO:0035335	peptidyl-tyrosine dephosphorylation	5.40e-02	1.00e+00	4.177	1	2	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.49e-02	1.00e+00	4.153	1	3	61
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	1	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.84e-02	1.00e+00	4.061	1	3	65
GO:0000922	spindle pole	6.10e-02	1.00e+00	3.996	1	3	68
GO:0016568	chromatin modification	6.10e-02	1.00e+00	3.996	1	2	68
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.27e-02	1.00e+00	3.954	1	4	70
GO:0005829	cytosol	6.48e-02	1.00e+00	1.280	4	33	1787
GO:0005737	cytoplasm	6.58e-02	1.00e+00	1.043	5	39	2633
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0006886	intracellular protein transport	7.91e-02	1.00e+00	3.608	1	1	89
GO:0061024	membrane organization	7.91e-02	1.00e+00	3.608	1	3	89
GO:0000209	protein polyubiquitination	8.17e-02	1.00e+00	3.560	1	3	92
GO:0032496	response to lipopolysaccharide	8.26e-02	1.00e+00	3.544	1	1	93
GO:0010467	gene expression	8.35e-02	1.00e+00	2.020	2	17	535
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	3	97
GO:0006413	translational initiation	8.77e-02	1.00e+00	3.454	1	12	99
GO:0005198	structural molecule activity	8.94e-02	1.00e+00	3.425	1	1	101
GO:0034641	cellular nitrogen compound metabolic process	9.28e-02	1.00e+00	3.369	1	3	105
GO:0003735	structural constituent of ribosome	9.61e-02	1.00e+00	3.315	1	8	109
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	4	112
GO:0007049	cell cycle	1.01e-01	1.00e+00	3.238	1	2	115
GO:0006974	cellular response to DNA damage stimulus	1.06e-01	1.00e+00	3.165	1	2	121
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	2	122
GO:0000082	G1/S transition of mitotic cell cycle	1.10e-01	1.00e+00	3.118	1	6	125
GO:0000398	mRNA splicing, via spliceosome	1.12e-01	1.00e+00	3.083	1	2	128
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	4	142
GO:0001701	in utero embryonic development	1.33e-01	1.00e+00	2.817	1	2	154
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	5	165
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0016071	mRNA metabolic process	1.46e-01	1.00e+00	2.674	1	11	170
GO:0016070	RNA metabolic process	1.61e-01	1.00e+00	2.529	1	11	188
GO:0004674	protein serine/threonine kinase activity	1.68e-01	1.00e+00	2.461	1	3	197
GO:0035556	intracellular signal transduction	1.69e-01	1.00e+00	2.447	1	3	199
GO:0070062	extracellular vesicular exosome	1.81e-01	1.00e+00	0.988	3	28	1641
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	6	217
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	6	247
GO:0008285	negative regulation of cell proliferation	2.28e-01	1.00e+00	1.970	1	3	277
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	15	1076
GO:0043066	negative regulation of apoptotic process	2.61e-01	1.00e+00	1.753	1	6	322
GO:0048471	perinuclear region of cytoplasm	2.76e-01	1.00e+00	1.657	1	7	344
GO:0044267	cellular protein metabolic process	2.81e-01	1.00e+00	1.624	1	13	352
GO:0006915	apoptotic process	3.21e-01	1.00e+00	1.400	1	4	411
GO:0016032	viral process	3.32e-01	1.00e+00	1.342	1	13	428
GO:0005634	nucleus	3.47e-01	1.00e+00	0.419	4	40	3246
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	6	456
GO:0003700	sequence-specific DNA binding transcription factor activity	4.25e-01	1.00e+00	0.899	1	9	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.59e-01	1.00e+00	0.753	1	8	644
GO:0005615	extracellular space	4.63e-01	1.00e+00	0.737	1	2	651
GO:0006355	regulation of transcription, DNA-templated	4.96e-01	1.00e+00	0.602	1	9	715
GO:0044281	small molecule metabolic process	5.57e-01	1.00e+00	0.362	1	8	844
GO:0005654	nucleoplasm	5.71e-01	1.00e+00	0.309	1	16	876
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	10	892
GO:0046872	metal ion binding	5.96e-01	1.00e+00	0.216	1	10	934
GO:0003677	DNA binding	6.01e-01	1.00e+00	0.196	1	12	947

Tai-Luciferase

reg-snw-52

Statistics

Genes (9)

Interactions (8)

Related GO terms (118)