reg-snw-9967

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	5.027	2.86e-28	1.15e-04	2.08e-04

tai-screen-luciferase-reg-snw-9967 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
EIF2S2	8894	11	-4.320	5.672	22	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
SIVA1	10572	1	-3.759	5.027	89	TF	-	Yes
HSF1	3297	8	-4.179	5.027	138	TF	-	Yes
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
[ THRAP3 ]	9967	1	2.507	5.027	22	-	-	-
CDC5L	988	15	-3.419	5.672	155	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
MRPS12	6183	THRAP3	9967	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
THRAP3	9967	SIVA1	10572	pd	<	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	THRAP3	9967	pd	>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
MRPS12	6183	SIVA1	10572	pd	<>	reg.ITFP.txt: no annot

Related GO terms (108)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005175	CD27 receptor binding	8.19e-04	1.00e+00	10.253	1	1	1
GO:0071987	WD40-repeat domain binding	8.19e-04	1.00e+00	10.253	1	1	1
GO:0002176	male germ cell proliferation	1.64e-03	1.00e+00	9.253	1	1	2
GO:0090231	regulation of spindle checkpoint	1.64e-03	1.00e+00	9.253	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.64e-03	1.00e+00	9.253	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.64e-03	1.00e+00	9.253	1	1	2
GO:0044822	poly(A) RNA binding	2.38e-03	1.00e+00	2.611	4	25	799
GO:0005850	eukaryotic translation initiation factor 2 complex	2.46e-03	1.00e+00	8.668	1	1	3
GO:0007143	female meiotic division	2.46e-03	1.00e+00	8.668	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	2.46e-03	1.00e+00	8.668	1	1	3
GO:0050658	RNA transport	3.27e-03	1.00e+00	8.253	1	1	4
GO:0030157	pancreatic juice secretion	3.27e-03	1.00e+00	8.253	1	1	4
GO:0000974	Prp19 complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000930	gamma-tubulin complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0060136	embryonic process involved in female pregnancy	4.91e-03	1.00e+00	7.668	1	1	6
GO:0006924	activation-induced cell death of T cells	4.91e-03	1.00e+00	7.668	1	2	6
GO:0048026	positive regulation of mRNA splicing, via spliceosome	4.91e-03	1.00e+00	7.668	1	1	6
GO:0030126	COPI vesicle coat	5.72e-03	1.00e+00	7.446	1	1	7
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	5.72e-03	1.00e+00	7.446	1	1	7
GO:0005662	DNA replication factor A complex	6.54e-03	1.00e+00	7.253	1	1	8
GO:0048255	mRNA stabilization	7.35e-03	1.00e+00	7.083	1	1	9
GO:0000956	nuclear-transcribed mRNA catabolic process	7.35e-03	1.00e+00	7.083	1	1	9
GO:0030518	intracellular steroid hormone receptor signaling pathway	8.17e-03	1.00e+00	6.931	1	1	10
GO:0007051	spindle organization	8.17e-03	1.00e+00	6.931	1	1	10
GO:0006412	translation	8.61e-03	1.00e+00	3.778	2	13	178
GO:0042809	vitamin D receptor binding	8.98e-03	1.00e+00	6.794	1	1	11
GO:0045120	pronucleus	8.98e-03	1.00e+00	6.794	1	1	11
GO:0015935	small ribosomal subunit	9.79e-03	1.00e+00	6.668	1	4	12
GO:0051297	centrosome organization	9.79e-03	1.00e+00	6.668	1	1	12
GO:0048205	COPI coating of Golgi vesicle	9.79e-03	1.00e+00	6.668	1	1	12
GO:0035371	microtubule plus-end	1.06e-02	1.00e+00	6.553	1	1	13
GO:0043234	protein complex	1.18e-02	1.00e+00	3.539	2	8	210
GO:0005515	protein binding	1.21e-02	1.00e+00	1.051	7	50	4124
GO:0008135	translation factor activity, nucleic acid binding	1.22e-02	1.00e+00	6.347	1	4	15
GO:0035145	exon-exon junction complex	1.22e-02	1.00e+00	6.347	1	1	15
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.38e-02	1.00e+00	6.166	1	1	17
GO:0001618	virus receptor activity	1.47e-02	1.00e+00	6.083	1	1	18
GO:0046966	thyroid hormone receptor binding	1.63e-02	1.00e+00	5.931	1	1	20
GO:0001892	embryonic placenta development	1.63e-02	1.00e+00	5.931	1	1	20
GO:0032720	negative regulation of tumor necrosis factor production	1.63e-02	1.00e+00	5.931	1	1	20
GO:0005761	mitochondrial ribosome	1.63e-02	1.00e+00	5.931	1	1	20
GO:0003682	chromatin binding	1.68e-02	1.00e+00	3.276	2	3	252
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	1.71e-02	1.00e+00	5.861	1	1	21
GO:0034605	cellular response to heat	1.79e-02	1.00e+00	5.794	1	1	22
GO:0040018	positive regulation of multicellular organism growth	1.79e-02	1.00e+00	5.794	1	1	22
GO:0001104	RNA polymerase II transcription cofactor activity	1.95e-02	1.00e+00	5.668	1	1	24
GO:0051219	phosphoprotein binding	2.03e-02	1.00e+00	5.610	1	3	25
GO:0016592	mediator complex	2.03e-02	1.00e+00	5.610	1	1	25
GO:0097191	extrinsic apoptotic signaling pathway	2.43e-02	1.00e+00	5.347	1	1	30
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	2.43e-02	1.00e+00	5.347	1	1	30
GO:0003712	transcription cofactor activity	2.75e-02	1.00e+00	5.166	1	1	34
GO:0030521	androgen receptor signaling pathway	2.83e-02	1.00e+00	5.124	1	3	35
GO:0003743	translation initiation factor activity	2.99e-02	1.00e+00	5.044	1	5	37
GO:0006952	defense response	2.99e-02	1.00e+00	5.044	1	1	37
GO:0032088	negative regulation of NF-kappaB transcription factor activity	3.15e-02	1.00e+00	4.968	1	1	39
GO:0097193	intrinsic apoptotic signaling pathway	3.95e-02	1.00e+00	4.639	1	1	49
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	4.03e-02	1.00e+00	4.610	1	1	50
GO:0008584	male gonad development	4.58e-02	1.00e+00	4.421	1	1	57
GO:0005179	hormone activity	4.81e-02	1.00e+00	4.347	1	1	60
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	1	61
GO:0000922	spindle pole	5.44e-02	1.00e+00	4.166	1	3	68
GO:0015630	microtubule cytoskeleton	5.98e-02	1.00e+00	4.025	1	2	75
GO:0016020	membrane	6.54e-02	1.00e+00	1.601	3	25	1207
GO:0005730	nucleolus	6.68e-02	1.00e+00	1.589	3	21	1217
GO:0006886	intracellular protein transport	7.07e-02	1.00e+00	3.778	1	1	89
GO:0061024	membrane organization	7.07e-02	1.00e+00	3.778	1	3	89
GO:0032496	response to lipopolysaccharide	7.37e-02	1.00e+00	3.714	1	1	93
GO:0000086	G2/M transition of mitotic cell cycle	7.68e-02	1.00e+00	3.653	1	3	97
GO:0009615	response to virus	7.68e-02	1.00e+00	3.653	1	2	97
GO:0006413	translational initiation	7.83e-02	1.00e+00	3.624	1	12	99
GO:0005198	structural molecule activity	7.98e-02	1.00e+00	3.595	1	1	101
GO:0003735	structural constituent of ribosome	8.59e-02	1.00e+00	3.485	1	8	109
GO:0006397	mRNA processing	8.67e-02	1.00e+00	3.472	1	2	110
GO:0004872	receptor activity	9.12e-02	1.00e+00	3.395	1	1	116
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	9.33e-02	1.00e+00	1.922	2	8	644
GO:0016607	nuclear speck	9.57e-02	1.00e+00	3.323	1	2	122
GO:0000398	mRNA splicing, via spliceosome	1.00e-01	1.00e+00	3.253	1	2	128
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.11e-01	1.00e+00	3.104	1	4	142
GO:0001701	in utero embryonic development	1.19e-01	1.00e+00	2.987	1	2	154
GO:0006367	transcription initiation from RNA polymerase II promoter	1.25e-01	1.00e+00	2.922	1	3	161
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	5	165
GO:0008380	RNA splicing	1.27e-01	1.00e+00	2.887	1	4	165
GO:0007283	spermatogenesis	1.30e-01	1.00e+00	2.861	1	2	168
GO:0003713	transcription coactivator activity	1.41e-01	1.00e+00	2.730	1	3	184
GO:0005737	cytoplasm	1.43e-01	1.00e+00	0.891	4	39	2633
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	6	217
GO:0005829	cytosol	1.67e-01	1.00e+00	1.035	3	33	1787
GO:0046872	metal ion binding	1.74e-01	1.00e+00	1.386	2	10	934
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	6	247
GO:0008285	negative regulation of cell proliferation	2.06e-01	1.00e+00	2.140	1	3	277
GO:0006351	transcription, DNA-templated	2.18e-01	1.00e+00	1.182	2	15	1076
GO:0006468	protein phosphorylation	2.22e-01	1.00e+00	2.020	1	3	301
GO:0000278	mitotic cell cycle	2.30e-01	1.00e+00	1.959	1	9	314
GO:0044267	cellular protein metabolic process	2.55e-01	1.00e+00	1.794	1	13	352
GO:0005634	nucleus	2.57e-01	1.00e+00	0.589	4	40	3246
GO:0045893	positive regulation of transcription, DNA-templated	2.70e-01	1.00e+00	1.695	1	6	377
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	6	456
GO:0010467	gene expression	3.63e-01	1.00e+00	1.190	1	17	535
GO:0003700	sequence-specific DNA binding transcription factor activity	3.88e-01	1.00e+00	1.069	1	9	582
GO:0070062	extracellular vesicular exosome	4.00e-01	1.00e+00	0.573	2	28	1641
GO:0005615	extracellular space	4.24e-01	1.00e+00	0.907	1	2	651
GO:0005739	mitochondrion	4.28e-01	1.00e+00	0.889	1	4	659
GO:0006355	regulation of transcription, DNA-templated	4.56e-01	1.00e+00	0.772	1	9	715
GO:0008270	zinc ion binding	4.62e-01	1.00e+00	0.748	1	5	727
GO:0005654	nucleoplasm	5.29e-01	1.00e+00	0.479	1	16	876
GO:0005524	ATP binding	5.35e-01	1.00e+00	0.453	1	10	892
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	12	947

Tai-Luciferase

reg-snw-9967

Statistics

Genes (8)

Interactions (8)

Related GO terms (108)