reg-snw-8624

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.286 1.02e-07 2.70e-02 2.12e-02
chia-screen-data-Fav-reg-snw-8624 subnetwork

Genes (24)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
AGPS 8540 23-2.4242.41027-YesYes
PHB 5245 82-2.7432.68936-YesYes
[ PSMG1 ] 8624 10.3642.28623---
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
PAPOLA 10914 9-1.9962.45519---
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
FBXL6 26233 28-2.2532.68922-Yes-
SYNCRIP 10492 42-2.4012.503144TFYesYes
SUV39H2 79723 27-2.3072.41021-YesYes
ALKBH8 91801 8-2.1472.4105-Yes-
FTSJ1 24140 43-2.4632.68935-YesYes
POLR2E 5434 30-2.0372.644201TFYes-
GSPT1 2935 32-2.3132.50317-YesYes
ETF1 2107 35-2.8292.5036-YesYes
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
CPSF3 51692 43-2.6862.50331-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
PRMT3 10196 5-1.8072.45426TF--
PSPH 5723 14-2.0632.38711-Yes-

Interactions (27)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PRMT3 10196 CPSF3 51692 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 PAPOLA 10914 pd > reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
PSMG1 8624 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
PSMG1 8624 PRMT3 10196 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 ALKBH8 91801 pd > reg.ITFP.txt: no annot
VARS 7407 PSMG1 8624 pd > reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
PSMG1 8624 FBXO22 26263 pd < reg.ITFP.txt: no annot
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot

Related GO terms (229)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0003747translation release factor activity5.79e-065.65e-028.668222
GO:0000398mRNA splicing, via spliceosome1.25e-051.22e-013.990515128
GO:0003723RNA binding2.26e-052.21e-013.305622247
GO:0008380RNA splicing4.25e-054.15e-013.624521165
GO:0031124mRNA 3'-end processing8.11e-057.92e-015.1243435
GO:0006369termination of RNA polymerase II transcription1.04e-041.00e+005.0053538
GO:0006379mRNA cleavage2.06e-041.00e+006.499229
GO:0010467gene expression2.18e-041.00e+002.412749535
GO:0006479protein methylation3.14e-041.00e+006.2092211
GO:0005654nucleoplasm8.11e-041.00e+001.894868876
GO:0030529ribonucleoprotein complex1.02e-031.00e+003.8963582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.09e-031.00e+003.8613584
GO:00063707-methylguanosine mRNA capping1.55e-031.00e+005.0832524
GO:0004832valine-tRNA ligase activity2.46e-031.00e+008.668111
GO:0080129proteasome core complex assembly2.46e-031.00e+008.668111
GO:0016149translation release factor activity, codon specific2.46e-031.00e+008.668111
GO:0002128tRNA nucleoside ribose methylation2.46e-031.00e+008.668111
GO:0016300tRNA (uracil) methyltransferase activity2.46e-031.00e+008.668111
GO:0008175tRNA methyltransferase activity2.46e-031.00e+008.668111
GO:0008609alkylglycerone-phosphate synthase activity2.46e-031.00e+008.668111
GO:0008079translation termination factor activity2.46e-031.00e+008.668111
GO:0006438valyl-tRNA aminoacylation2.46e-031.00e+008.668111
GO:0050434positive regulation of viral transcription3.28e-031.00e+004.5392535
GO:0000775chromosome, centromeric region4.48e-031.00e+004.3112641
GO:0048742regulation of skeletal muscle fiber development4.91e-031.00e+007.668112
GO:0034969histone arginine methylation4.91e-031.00e+007.668112
GO:0004647phosphoserine phosphatase activity4.91e-031.00e+007.668112
GO:0005846nuclear cap binding complex4.91e-031.00e+007.668112
GO:0002176male germ cell proliferation4.91e-031.00e+007.668112
GO:0008611ether lipid biosynthetic process4.91e-031.00e+007.668112
GO:0006406mRNA export from nucleus5.14e-031.00e+004.2092744
GO:0005829cytosol6.62e-031.00e+001.18710881787
GO:0006368transcription elongation from RNA polymerase II promoter7.12e-031.00e+003.9682852
GO:0008762UDP-N-acetylmuramate dehydrogenase activity7.36e-031.00e+007.083113
GO:0005850eukaryotic translation initiation factor 2 complex7.36e-031.00e+007.083123
GO:0036123histone H3-K9 dimethylation7.36e-031.00e+007.083113
GO:0002098tRNA wobble uridine modification7.36e-031.00e+007.083113
GO:0006563L-serine metabolic process7.36e-031.00e+007.083113
GO:0016274protein-arginine N-methyltransferase activity7.36e-031.00e+007.083113
GO:0008469histone-arginine N-methyltransferase activity7.36e-031.00e+007.083113
GO:0006366transcription from RNA polymerase II promoter8.93e-031.00e+002.255423341
GO:0021930cerebellar granule cell precursor proliferation9.80e-031.00e+006.668114
GO:0043248proteasome assembly9.80e-031.00e+006.668114
GO:0045292mRNA cis splicing, via spliceosome9.80e-031.00e+006.668114
GO:0097452GAIT complex9.80e-031.00e+006.668124
GO:0004652polynucleotide adenylyltransferase activity9.80e-031.00e+006.668114
GO:0031442positive regulation of mRNA 3'-end processing9.80e-031.00e+006.668114
GO:0006290pyrimidine dimer repair9.80e-031.00e+006.668124
GO:0006449regulation of translational termination9.80e-031.00e+006.668114
GO:0006333chromatin assembly or disassembly9.80e-031.00e+006.668114
GO:0036124histone H3-K9 trimethylation9.80e-031.00e+006.668124
GO:0043631RNA polyadenylation9.80e-031.00e+006.668114
GO:0072341modified amino acid binding9.80e-031.00e+006.668114
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity9.80e-031.00e+006.668114
GO:0006564L-serine biosynthetic process9.80e-031.00e+006.668114
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine9.80e-031.00e+006.668114
GO:0006415translational termination1.03e-021.00e+003.6912263
GO:0004521endoribonuclease activity1.22e-021.00e+006.347115
GO:0008610lipid biosynthetic process1.22e-021.00e+006.347115
GO:0006398histone mRNA 3'-end processing1.22e-021.00e+006.347115
GO:0070934CRD-mediated mRNA stabilization1.22e-021.00e+006.347125
GO:0006282regulation of DNA repair1.22e-021.00e+006.347125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.22e-021.00e+006.347115
GO:0002161aminoacyl-tRNA editing activity1.22e-021.00e+006.347115
GO:0071204histone pre-mRNA 3'end processing complex1.22e-021.00e+006.347115
GO:0001649osteoblast differentiation1.40e-021.00e+003.4592574
GO:0050847progesterone receptor signaling pathway1.47e-021.00e+006.083126
GO:0002181cytoplasmic translation1.47e-021.00e+006.083116
GO:0001055RNA polymerase II activity1.47e-021.00e+006.083136
GO:0042754negative regulation of circadian rhythm1.47e-021.00e+006.083126
GO:0046974histone methyltransferase activity (H3-K9 specific)1.47e-021.00e+006.083116
GO:0070937CRD-mediated mRNA stability complex1.47e-021.00e+006.083126
GO:0002199zona pellucida receptor complex1.71e-021.00e+005.861147
GO:0007140male meiosis1.71e-021.00e+005.861117
GO:0000731DNA synthesis involved in DNA repair1.71e-021.00e+005.861117
GO:0006301postreplication repair1.71e-021.00e+005.861127
GO:00084095'-3' exonuclease activity1.71e-021.00e+005.861127
GO:0000339RNA cap binding1.71e-021.00e+005.861117
GO:0005832chaperonin-containing T-complex1.71e-021.00e+005.861147
GO:0005845mRNA cap binding complex1.95e-021.00e+005.668118
GO:0070628proteasome binding1.95e-021.00e+005.668118
GO:0006450regulation of translational fidelity1.95e-021.00e+005.668118
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors1.95e-021.00e+005.668118
GO:0010944negative regulation of transcription by competitive promoter binding1.95e-021.00e+005.668118
GO:0071949FAD binding1.95e-021.00e+005.668118
GO:0010388cullin deneddylation1.95e-021.00e+005.668148
GO:0005739mitochondrion2.00e-021.00e+001.626532659
GO:0010225response to UV-C2.19e-021.00e+005.499129
GO:0030488tRNA methylation2.19e-021.00e+005.499129
GO:0071354cellular response to interleukin-62.19e-021.00e+005.499119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.19e-021.00e+005.499129
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.19e-021.00e+005.499139
GO:0005736DNA-directed RNA polymerase I complex2.43e-021.00e+005.3471410
GO:0005095GTPase inhibitor activity2.43e-021.00e+005.3471110
GO:0008143poly(A) binding2.43e-021.00e+005.3471210
GO:0001054RNA polymerase I activity2.43e-021.00e+005.3471410
GO:0060766negative regulation of androgen receptor signaling pathway2.67e-021.00e+005.2091411
GO:0008652cellular amino acid biosynthetic process2.67e-021.00e+005.2091211
GO:0008334histone mRNA metabolic process2.67e-021.00e+005.2091111
GO:0005666DNA-directed RNA polymerase III complex3.15e-021.00e+004.9681313
GO:0005665DNA-directed RNA polymerase II, core complex3.15e-021.00e+004.9681313
GO:0001056RNA polymerase III activity3.15e-021.00e+004.9681313
GO:0000287magnesium ion binding3.21e-021.00e+002.82324115
GO:0006386termination of RNA polymerase III transcription3.39e-021.00e+004.8611314
GO:0006385transcription elongation from RNA polymerase III promoter3.39e-021.00e+004.8611314
GO:0016575histone deacetylation3.39e-021.00e+004.8611214
GO:0005737cytoplasm3.63e-021.00e+000.765111272633
GO:0008135translation factor activity, nucleic acid binding3.63e-021.00e+004.7621415
GO:0000188inactivation of MAPK activity3.63e-021.00e+004.7621115
GO:0007339binding of sperm to zona pellucida3.63e-021.00e+004.7621415
GO:0005515protein binding3.63e-021.00e+000.566151984124
GO:0003887DNA-directed DNA polymerase activity3.86e-021.00e+004.6681216
GO:0005782peroxisomal matrix3.86e-021.00e+004.6681116
GO:0043022ribosome binding4.10e-021.00e+004.5811217
GO:0031667response to nutrient levels4.10e-021.00e+004.5811217
GO:0044822poly(A) RNA binding4.17e-021.00e+001.348545799
GO:0003899DNA-directed RNA polymerase activity4.34e-021.00e+004.4991318
GO:0031047gene silencing by RNA4.34e-021.00e+004.4991218
GO:0006378mRNA polyadenylation4.34e-021.00e+004.4991318
GO:0033574response to testosterone4.34e-021.00e+004.4991118
GO:0031397negative regulation of protein ubiquitination4.34e-021.00e+004.4991218
GO:0006913nucleocytoplasmic transport4.81e-021.00e+004.3471220
GO:0034080CENP-A containing nucleosome assembly4.81e-021.00e+004.3471220
GO:0071346cellular response to interferon-gamma4.81e-021.00e+004.3471220
GO:0005720nuclear heterochromatin4.81e-021.00e+004.3471320
GO:0071897DNA biosynthetic process4.81e-021.00e+004.3471220
GO:0034660ncRNA metabolic process4.81e-021.00e+004.3471120
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic5.04e-021.00e+004.2761221
GO:0051084'de novo' posttranslational protein folding5.28e-021.00e+004.2091422
GO:0000387spliceosomal snRNP assembly5.28e-021.00e+004.2091122
GO:0044267cellular protein metabolic process5.37e-021.00e+001.794314352
GO:0000049tRNA binding5.51e-021.00e+004.1451223
GO:0008180COP9 signalosome5.74e-021.00e+004.0831624
GO:0000976transcription regulatory region sequence-specific DNA binding5.97e-021.00e+004.0251325
GO:0030145manganese ion binding6.21e-021.00e+003.9681326
GO:0009267cellular response to starvation6.21e-021.00e+003.9681126
GO:0006360transcription from RNA polymerase I promoter6.44e-021.00e+003.9141427
GO:0016071mRNA metabolic process6.48e-021.00e+002.259210170
GO:0006418tRNA aminoacylation for protein translation6.90e-021.00e+003.8101429
GO:0006383transcription from RNA polymerase III promoter6.90e-021.00e+003.8101629
GO:0005778peroxisomal membrane6.90e-021.00e+003.8101329
GO:0006446regulation of translational initiation6.90e-021.00e+003.8101229
GO:0006412translation7.02e-021.00e+002.193212178
GO:0004842ubiquitin-protein transferase activity7.09e-021.00e+002.185217179
GO:0008168methyltransferase activity7.13e-021.00e+003.7621230
GO:0045111intermediate filament cytoskeleton7.36e-021.00e+003.7141331
GO:0016070RNA metabolic process7.72e-021.00e+002.114210188
GO:0017148negative regulation of translation7.81e-021.00e+003.6241533
GO:0007254JNK cascade8.04e-021.00e+003.5811134
GO:0044297cell body8.27e-021.00e+003.5391535
GO:0016032viral process8.57e-021.00e+001.512330428
GO:0003743translation initiation factor activity8.72e-021.00e+003.4591837
GO:0006281DNA repair8.81e-021.00e+002.003224203
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process8.94e-021.00e+003.4211438
GO:0048511rhythmic process8.94e-021.00e+003.4211538
GO:0006396RNA processing9.39e-021.00e+003.3471440
GO:0005840ribosome9.39e-021.00e+003.3471240
GO:0006283transcription-coupled nucleotide-excision repair9.39e-021.00e+003.3471640
GO:0003684damaged DNA binding9.62e-021.00e+003.3111141
GO:0009612response to mechanical stimulus1.07e-011.00e+003.1451246
GO:0032481positive regulation of type I interferon production1.12e-011.00e+003.0831348
GO:0005777peroxisome1.16e-011.00e+003.0251250
GO:0006334nucleosome assembly1.18e-011.00e+002.9961451
GO:0006289nucleotide-excision repair1.23e-011.00e+002.9411653
GO:0006338chromatin remodeling1.27e-011.00e+002.8871755
GO:0016311dephosphorylation1.27e-011.00e+002.8871355
GO:0008584male gonad development1.31e-011.00e+002.8361157
GO:0042826histone deacetylase binding1.33e-011.00e+002.8101558
GO:0000785chromatin1.36e-011.00e+002.7861659
GO:0071013catalytic step 2 spliceosome1.40e-011.00e+002.7381561
GO:0006464cellular protein modification process1.40e-011.00e+002.7381461
GO:0030018Z disc1.46e-011.00e+002.6681364
GO:0030308negative regulation of cell growth1.59e-011.00e+002.5391370
GO:0051082unfolded protein binding1.59e-011.00e+002.5391570
GO:0071456cellular response to hypoxia1.71e-011.00e+002.4211276
GO:0055114oxidation-reduction process1.74e-011.00e+001.40229308
GO:0045892negative regulation of transcription, DNA-templated1.82e-011.00e+001.360217317
GO:0046872metal ion binding1.92e-011.00e+000.801424934
GO:0044255cellular lipid metabolic process1.97e-011.00e+002.1931289
GO:0005506iron ion binding2.03e-011.00e+002.1451492
GO:0000209protein polyubiquitination2.03e-011.00e+002.1451692
GO:0006511ubiquitin-dependent protein catabolic process2.03e-011.00e+002.1451692
GO:0006260DNA replication2.07e-011.00e+002.1141994
GO:0006457protein folding2.13e-011.00e+002.0691597
GO:0006413translational initiation2.17e-011.00e+002.0391699
GO:0034641cellular nitrogen compound metabolic process2.29e-011.00e+001.95415105
GO:0005783endoplasmic reticulum2.40e-011.00e+001.095212381
GO:0042981regulation of apoptotic process2.42e-011.00e+001.86114112
GO:0043005neuron projection2.44e-011.00e+001.84816113
GO:0007049cell cycle2.48e-011.00e+001.82318115
GO:0005634nucleus2.50e-011.00e+000.326101583246
GO:0003924GTPase activity2.55e-011.00e+001.77417119
GO:0006974cellular response to DNA damage stimulus2.59e-011.00e+001.750111121
GO:0000082G1/S transition of mitotic cell cycle2.66e-011.00e+001.70314125
GO:0006184GTP catabolic process2.75e-011.00e+001.64617130
GO:0044212transcription regulatory region DNA binding2.98e-011.00e+001.509113143
GO:0005622intracellular3.02e-011.00e+001.48912145
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.10e-011.00e+000.836229456
GO:0001701in utero embryonic development3.17e-011.00e+001.40217154
GO:0006367transcription initiation from RNA polymerase II promoter3.29e-011.00e+001.338118161
GO:0005874microtubule3.33e-011.00e+001.320110163
GO:0005730nucleolus3.50e-011.00e+000.4194741217
GO:0000166nucleotide binding3.54e-011.00e+001.209113176
GO:0016567protein ubiquitination3.73e-011.00e+001.114114188
GO:0005524ATP binding3.78e-011.00e+000.453337892
GO:0005743mitochondrial inner membrane3.87e-011.00e+001.04619197
GO:0005525GTP binding3.87e-011.00e+001.046112197
GO:0030154cell differentiation3.98e-011.00e+000.99615204
GO:0019899enzyme binding4.07e-011.00e+000.95417210
GO:0043231intracellular membrane-bounded organelle4.19e-011.00e+000.90018218
GO:0003682chromatin binding4.66e-011.00e+000.691115252
GO:0006508proteolysis4.82e-011.00e+000.624111264
GO:0008285negative regulation of cell proliferation4.99e-011.00e+000.555111277
GO:0006355regulation of transcription, DNA-templated5.33e-011.00e+000.187231715
GO:0008270zinc ion binding5.43e-011.00e+000.163239727
GO:0000278mitotic cell cycle5.44e-011.00e+000.374128314
GO:0016020membrane5.84e-011.00e+000.0163561207
GO:0005509calcium ion binding5.85e-011.00e+000.21319351
GO:0042802identical protein binding5.88e-011.00e+000.201115354
GO:0045893positive regulation of transcription, DNA-templated6.12e-011.00e+000.110121377
GO:0044281small molecule metabolic process6.27e-011.00e+00-0.053235844
GO:0042803protein homodimerization activity6.59e-011.00e+00-0.073113428
GO:0045087innate immune response6.80e-011.00e+00-0.152112452
GO:0005887integral component of plasma membrane7.67e-011.00e+00-0.49918575
GO:0007165signal transduction7.92e-011.00e+00-0.603124618
GO:0003677DNA binding9.14e-011.00e+00-1.219152947
GO:0070062extracellular vesicular exosome9.30e-011.00e+00-1.0122511641
GO:0006351transcription, DNA-templated9.40e-011.00e+00-1.4031471076
GO:0005886plasma membrane9.92e-011.00e+00-2.1321461784