int-snw-121536

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.821	2.37e-15	5.75e-04	3.83e-03

chia-screen-data-Fav-int-snw-121536 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TGFB1	7040	2	-1.997	2.821	60	-	-
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
[ AEBP2 ]	121536	1	-1.218	2.821	12	-	-
PHB2	11331	5	-2.236	2.994	140	Yes	-
SUZ12	23512	2	-1.792	2.904	42	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
MED13L	23389	12	-2.550	3.159	21	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
EZH2	2146	2	-1.631	2.904	105	-	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EZH2	2146	YY1	7528	pp	--	int.I2D: BioGrid, BCI
EZH2	2146	AEBP2	121536	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EZH2	2146	SUZ12	23512	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, BioGrid_Fly, BioGrid_Mouse, IntAct_Mouse, BCI, HPRD, IntAct_Fly; int.Ravasi: -; int.HPRD: in vivo
SUZ12	23512	AEBP2	121536	pp	--	int.I2D: BioGrid, BIND, HPRD; int.Ravasi: -; int.HPRD: in vitro
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EZH2	2146	POU5F1	5460	pp	--	int.I2D: BioGrid
EZH2	2146	MED13L	23389	pp	--	int.I2D: BioGrid_Fly
TGFB1	7040	SUZ12	23512	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
EZH2	2146	PHB2	11331	pp	--	int.I2D: BioGrid
PSMD2	5708	PHB2	11331	pp	--	int.I2D: IntAct_Yeast

Related GO terms (341)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0035098	ESC/E(Z) complex	3.29e-07	4.75e-03	7.687	3	3	15
GO:0005654	nucleoplasm	1.95e-06	2.81e-02	2.929	8	64	1082
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	8.50e-06	1.23e-01	3.439	6	37	570
GO:0003723	RNA binding	1.22e-05	1.76e-01	3.913	5	18	342
GO:0060744	mammary gland branching involved in thelarche	1.31e-05	1.89e-01	8.424	2	2	6
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	1.31e-05	1.89e-01	8.424	2	2	6
GO:0042054	histone methyltransferase activity	2.44e-05	3.52e-01	8.009	2	3	8
GO:0006366	transcription from RNA polymerase II promoter	3.26e-05	4.70e-01	3.620	5	30	419
GO:0060391	positive regulation of SMAD protein import into nucleus	4.79e-05	6.91e-01	7.549	2	4	11
GO:0031011	Ino80 complex	7.91e-05	1.00e+00	7.201	2	6	14
GO:0010718	positive regulation of epithelial to mesenchymal transition	2.59e-04	1.00e+00	6.365	2	4	25
GO:0044212	transcription regulatory region DNA binding	5.14e-04	1.00e+00	4.201	3	17	168
GO:0003714	transcription corepressor activity	6.09e-04	1.00e+00	4.118	3	11	178
GO:0043406	positive regulation of MAP kinase activity	8.84e-04	1.00e+00	5.485	2	2	46
GO:0005515	protein binding	9.66e-04	1.00e+00	1.037	12	198	6024
GO:0014013	regulation of gliogenesis	9.71e-04	1.00e+00	10.009	1	1	1
GO:0009817	defense response to fungus, incompatible interaction	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.71e-04	1.00e+00	10.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.71e-04	1.00e+00	10.009	1	1	1
GO:0010742	macrophage derived foam cell differentiation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0045605	negative regulation of epidermal cell differentiation	9.71e-04	1.00e+00	10.009	1	1	1
GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity	9.71e-04	1.00e+00	10.009	1	1	1
GO:0061035	regulation of cartilage development	9.71e-04	1.00e+00	10.009	1	1	1
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9.71e-04	1.00e+00	10.009	1	1	1
GO:0060751	branch elongation involved in mammary gland duct branching	9.71e-04	1.00e+00	10.009	1	1	1
GO:0009611	response to wounding	1.13e-03	1.00e+00	5.308	2	5	52
GO:0003713	transcription coactivator activity	1.39e-03	1.00e+00	3.705	3	24	237
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.45e-03	1.00e+00	5.126	2	5	59
GO:0006355	regulation of transcription, DNA-templated	1.85e-03	1.00e+00	2.369	5	43	997
GO:0060242	contact inhibition	1.94e-03	1.00e+00	9.009	1	1	2
GO:0045066	regulatory T cell differentiation	1.94e-03	1.00e+00	9.009	1	1	2
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.94e-03	1.00e+00	9.009	1	1	2
GO:0006403	RNA localization	1.94e-03	1.00e+00	9.009	1	1	2
GO:0060312	regulation of blood vessel remodeling	1.94e-03	1.00e+00	9.009	1	1	2
GO:0019046	release from viral latency	1.94e-03	1.00e+00	9.009	1	2	2
GO:0032943	mononuclear cell proliferation	1.94e-03	1.00e+00	9.009	1	1	2
GO:0046732	active induction of host immune response by virus	1.94e-03	1.00e+00	9.009	1	1	2
GO:1901203	positive regulation of extracellular matrix assembly	1.94e-03	1.00e+00	9.009	1	1	2
GO:0009786	regulation of asymmetric cell division	1.94e-03	1.00e+00	9.009	1	1	2
GO:2000628	regulation of miRNA metabolic process	1.94e-03	1.00e+00	9.009	1	1	2
GO:0034696	response to prostaglandin F	1.94e-03	1.00e+00	9.009	1	1	2
GO:0043932	ossification involved in bone remodeling	1.94e-03	1.00e+00	9.009	1	1	2
GO:0019049	evasion or tolerance of host defenses by virus	1.94e-03	1.00e+00	9.009	1	1	2
GO:0005634	nucleus	2.58e-03	1.00e+00	1.176	10	159	4559
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	2.91e-03	1.00e+00	8.424	1	1	3
GO:0042306	regulation of protein import into nucleus	2.91e-03	1.00e+00	8.424	1	2	3
GO:0060913	cardiac cell fate determination	2.91e-03	1.00e+00	8.424	1	1	3
GO:0002513	tolerance induction to self antigen	2.91e-03	1.00e+00	8.424	1	1	3
GO:0051154	negative regulation of striated muscle cell differentiation	2.91e-03	1.00e+00	8.424	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	2.91e-03	1.00e+00	8.424	1	1	3
GO:0070314	G1 to G0 transition	2.91e-03	1.00e+00	8.424	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.91e-03	1.00e+00	8.424	1	1	3
GO:0010467	gene expression	3.16e-03	1.00e+00	2.623	4	45	669
GO:0016363	nuclear matrix	3.41e-03	1.00e+00	4.501	2	6	91
GO:0003682	chromatin binding	3.49e-03	1.00e+00	3.241	3	19	327
GO:0010936	negative regulation of macrophage cytokine production	3.88e-03	1.00e+00	8.009	1	1	4
GO:0051152	positive regulation of smooth muscle cell differentiation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0060364	frontal suture morphogenesis	3.88e-03	1.00e+00	8.009	1	1	4
GO:0046976	histone methyltransferase activity (H3-K27 specific)	3.88e-03	1.00e+00	8.009	1	1	4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3.88e-03	1.00e+00	8.009	1	1	4
GO:0010716	negative regulation of extracellular matrix disassembly	3.88e-03	1.00e+00	8.009	1	2	4
GO:0031536	positive regulation of exit from mitosis	3.88e-03	1.00e+00	8.009	1	1	4
GO:0070734	histone H3-K27 methylation	3.88e-03	1.00e+00	8.009	1	1	4
GO:0043565	sequence-specific DNA binding	4.09e-03	1.00e+00	3.159	3	11	346
GO:0003677	DNA binding	4.46e-03	1.00e+00	2.080	5	49	1218
GO:0070461	SAGA-type complex	4.84e-03	1.00e+00	7.687	1	2	5
GO:0001714	endodermal cell fate specification	4.84e-03	1.00e+00	7.687	1	1	5
GO:0007182	common-partner SMAD protein phosphorylation	4.84e-03	1.00e+00	7.687	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.84e-03	1.00e+00	7.687	1	2	5
GO:0042482	positive regulation of odontogenesis	4.84e-03	1.00e+00	7.687	1	1	5
GO:0051098	regulation of binding	4.84e-03	1.00e+00	7.687	1	1	5
GO:0016202	regulation of striated muscle tissue development	4.84e-03	1.00e+00	7.687	1	1	5
GO:0051101	regulation of DNA binding	4.84e-03	1.00e+00	7.687	1	1	5
GO:0071168	protein localization to chromatin	4.84e-03	1.00e+00	7.687	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	4.84e-03	1.00e+00	7.687	1	1	5
GO:0006325	chromatin organization	5.66e-03	1.00e+00	4.126	2	12	118
GO:0070937	CRD-mediated mRNA stability complex	5.81e-03	1.00e+00	7.424	1	3	6
GO:0021695	cerebellar cortex development	5.81e-03	1.00e+00	7.424	1	1	6
GO:0085029	extracellular matrix assembly	5.81e-03	1.00e+00	7.424	1	1	6
GO:0007435	salivary gland morphogenesis	5.81e-03	1.00e+00	7.424	1	1	6
GO:0007406	negative regulation of neuroblast proliferation	5.81e-03	1.00e+00	7.424	1	1	6
GO:0045892	negative regulation of transcription, DNA-templated	6.71e-03	1.00e+00	2.904	3	24	413
GO:0016574	histone ubiquitination	6.78e-03	1.00e+00	7.201	1	1	7
GO:0032930	positive regulation of superoxide anion generation	6.78e-03	1.00e+00	7.201	1	2	7
GO:0001739	sex chromatin	6.78e-03	1.00e+00	7.201	1	1	7
GO:0050765	negative regulation of phagocytosis	6.78e-03	1.00e+00	7.201	1	1	7
GO:0007184	SMAD protein import into nucleus	6.78e-03	1.00e+00	7.201	1	1	7
GO:0005114	type II transforming growth factor beta receptor binding	6.78e-03	1.00e+00	7.201	1	1	7
GO:0032801	receptor catabolic process	6.78e-03	1.00e+00	7.201	1	1	7
GO:0045814	negative regulation of gene expression, epigenetic	6.78e-03	1.00e+00	7.201	1	2	7
GO:0070723	response to cholesterol	6.78e-03	1.00e+00	7.201	1	1	7
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	7.74e-03	1.00e+00	7.009	1	2	8
GO:0070688	MLL5-L complex	7.74e-03	1.00e+00	7.009	1	1	8
GO:0034616	response to laminar fluid shear stress	7.74e-03	1.00e+00	7.009	1	1	8
GO:0048642	negative regulation of skeletal muscle tissue development	7.74e-03	1.00e+00	7.009	1	1	8
GO:0043254	regulation of protein complex assembly	7.74e-03	1.00e+00	7.009	1	1	8
GO:0010763	positive regulation of fibroblast migration	7.74e-03	1.00e+00	7.009	1	1	8
GO:0007183	SMAD protein complex assembly	7.74e-03	1.00e+00	7.009	1	1	8
GO:0010628	positive regulation of gene expression	8.55e-03	1.00e+00	3.819	2	7	146
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:2000679	positive regulation of transcription regulatory region DNA binding	8.70e-03	1.00e+00	6.839	1	1	9
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	8.70e-03	1.00e+00	6.839	1	5	9
GO:0010225	response to UV-C	8.70e-03	1.00e+00	6.839	1	2	9
GO:0048188	Set1C/COMPASS complex	8.70e-03	1.00e+00	6.839	1	4	9
GO:0031065	positive regulation of histone deacetylation	8.70e-03	1.00e+00	6.839	1	2	9
GO:0000400	four-way junction DNA binding	8.70e-03	1.00e+00	6.839	1	1	9
GO:0006974	cellular response to DNA damage stimulus	9.12e-03	1.00e+00	3.770	2	7	151
GO:0006351	transcription, DNA-templated	9.29e-03	1.00e+00	1.833	5	57	1446
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	9.67e-03	1.00e+00	6.687	1	1	10
GO:0035413	positive regulation of catenin import into nucleus	9.67e-03	1.00e+00	6.687	1	2	10
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	9.67e-03	1.00e+00	6.687	1	2	10
GO:0022408	negative regulation of cell-cell adhesion	1.06e-02	1.00e+00	6.549	1	1	11
GO:0070306	lens fiber cell differentiation	1.06e-02	1.00e+00	6.549	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.06e-02	1.00e+00	6.549	1	3	11
GO:0045120	pronucleus	1.06e-02	1.00e+00	6.549	1	2	11
GO:0008354	germ cell migration	1.06e-02	1.00e+00	6.549	1	1	11
GO:0032740	positive regulation of interleukin-17 production	1.06e-02	1.00e+00	6.549	1	2	11
GO:0000398	mRNA splicing, via spliceosome	1.07e-02	1.00e+00	3.651	2	15	164
GO:2000249	regulation of actin cytoskeleton reorganization	1.16e-02	1.00e+00	6.424	1	1	12
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.16e-02	1.00e+00	6.424	1	1	12
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.16e-02	1.00e+00	6.424	1	1	12
GO:0005838	proteasome regulatory particle	1.16e-02	1.00e+00	6.424	1	1	12
GO:0035198	miRNA binding	1.16e-02	1.00e+00	6.424	1	1	12
GO:0019048	modulation by virus of host morphology or physiology	1.16e-02	1.00e+00	6.424	1	1	12
GO:0005667	transcription factor complex	1.21e-02	1.00e+00	3.558	2	17	175
GO:0071480	cellular response to gamma radiation	1.26e-02	1.00e+00	6.308	1	1	13
GO:0002028	regulation of sodium ion transport	1.26e-02	1.00e+00	6.308	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.26e-02	1.00e+00	6.308	1	2	13
GO:0030214	hyaluronan catabolic process	1.26e-02	1.00e+00	6.308	1	1	13
GO:0050921	positive regulation of chemotaxis	1.26e-02	1.00e+00	6.308	1	1	13
GO:0031334	positive regulation of protein complex assembly	1.26e-02	1.00e+00	6.308	1	2	13
GO:0030234	enzyme regulator activity	1.26e-02	1.00e+00	6.308	1	2	13
GO:0033280	response to vitamin D	1.35e-02	1.00e+00	6.201	1	1	14
GO:0030279	negative regulation of ossification	1.35e-02	1.00e+00	6.201	1	2	14
GO:0032270	positive regulation of cellular protein metabolic process	1.35e-02	1.00e+00	6.201	1	1	14
GO:0042307	positive regulation of protein import into nucleus	1.45e-02	1.00e+00	6.102	1	4	15
GO:0043011	myeloid dendritic cell differentiation	1.45e-02	1.00e+00	6.102	1	2	15
GO:0035066	positive regulation of histone acetylation	1.45e-02	1.00e+00	6.102	1	1	15
GO:0016571	histone methylation	1.45e-02	1.00e+00	6.102	1	2	15
GO:0043981	histone H4-K5 acetylation	1.45e-02	1.00e+00	6.102	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.45e-02	1.00e+00	6.102	1	3	15
GO:0001824	blastocyst development	1.45e-02	1.00e+00	6.102	1	2	15
GO:0043982	histone H4-K8 acetylation	1.45e-02	1.00e+00	6.102	1	5	15
GO:0060749	mammary gland alveolus development	1.45e-02	1.00e+00	6.102	1	2	15
GO:0042176	regulation of protein catabolic process	1.54e-02	1.00e+00	6.009	1	2	16
GO:0048535	lymph node development	1.54e-02	1.00e+00	6.009	1	1	16
GO:0043274	phospholipase binding	1.54e-02	1.00e+00	6.009	1	1	16
GO:0051276	chromosome organization	1.54e-02	1.00e+00	6.009	1	2	16
GO:0048593	camera-type eye morphogenesis	1.54e-02	1.00e+00	6.009	1	1	16
GO:0006796	phosphate-containing compound metabolic process	1.64e-02	1.00e+00	5.921	1	1	17
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.64e-02	1.00e+00	5.921	1	1	17
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1.64e-02	1.00e+00	5.921	1	1	17
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.64e-02	1.00e+00	5.921	1	3	17
GO:0022624	proteasome accessory complex	1.64e-02	1.00e+00	5.921	1	1	17
GO:0035307	positive regulation of protein dephosphorylation	1.64e-02	1.00e+00	5.921	1	1	17
GO:0006754	ATP biosynthetic process	1.73e-02	1.00e+00	5.839	1	2	18
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	1.73e-02	1.00e+00	5.839	1	1	18
GO:0071158	positive regulation of cell cycle arrest	1.83e-02	1.00e+00	5.761	1	2	19
GO:0043984	histone H4-K16 acetylation	1.83e-02	1.00e+00	5.761	1	5	19
GO:0071549	cellular response to dexamethasone stimulus	1.92e-02	1.00e+00	5.687	1	3	20
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.92e-02	1.00e+00	5.687	1	1	20
GO:0045930	negative regulation of mitotic cell cycle	1.92e-02	1.00e+00	5.687	1	1	20
GO:0008156	negative regulation of DNA replication	1.92e-02	1.00e+00	5.687	1	1	20
GO:0045596	negative regulation of cell differentiation	1.92e-02	1.00e+00	5.687	1	1	20
GO:0008380	RNA splicing	2.00e-02	1.00e+00	3.176	2	22	228
GO:0007492	endoderm development	2.02e-02	1.00e+00	5.616	1	2	21
GO:0010575	positive regulation vascular endothelial growth factor production	2.02e-02	1.00e+00	5.616	1	1	21
GO:0032967	positive regulation of collagen biosynthetic process	2.02e-02	1.00e+00	5.616	1	3	21
GO:0043029	T cell homeostasis	2.02e-02	1.00e+00	5.616	1	1	21
GO:0000123	histone acetyltransferase complex	2.02e-02	1.00e+00	5.616	1	6	21
GO:0006306	DNA methylation	2.12e-02	1.00e+00	5.549	1	1	22
GO:0003823	antigen binding	2.12e-02	1.00e+00	5.549	1	2	22
GO:0045787	positive regulation of cell cycle	2.12e-02	1.00e+00	5.549	1	2	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.12e-02	1.00e+00	5.549	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.12e-02	1.00e+00	5.549	1	4	22
GO:0043025	neuronal cell body	2.29e-02	1.00e+00	3.072	2	9	245
GO:0000060	protein import into nucleus, translocation	2.31e-02	1.00e+00	5.424	1	1	24
GO:0006611	protein export from nucleus	2.40e-02	1.00e+00	5.365	1	3	25
GO:0031519	PcG protein complex	2.40e-02	1.00e+00	5.365	1	1	25
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	2.40e-02	1.00e+00	5.365	1	3	25
GO:0035329	hippo signaling	2.50e-02	1.00e+00	5.308	1	5	26
GO:0071902	positive regulation of protein serine/threonine kinase activity	2.50e-02	1.00e+00	5.308	1	2	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.50e-02	1.00e+00	5.308	1	3	26
GO:0048565	digestive tract development	2.50e-02	1.00e+00	5.308	1	2	26
GO:0030331	estrogen receptor binding	2.59e-02	1.00e+00	5.254	1	2	27
GO:0071339	MLL1 complex	2.59e-02	1.00e+00	5.254	1	6	27
GO:0009314	response to radiation	2.59e-02	1.00e+00	5.254	1	1	27
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.63e-02	1.00e+00	2.964	2	23	264
GO:0050714	positive regulation of protein secretion	2.69e-02	1.00e+00	5.201	1	3	28
GO:0003700	sequence-specific DNA binding transcription factor activity	2.77e-02	1.00e+00	2.145	3	39	699
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.78e-02	1.00e+00	5.151	1	2	29
GO:0030501	positive regulation of bone mineralization	2.78e-02	1.00e+00	5.151	1	1	29
GO:0006954	inflammatory response	2.87e-02	1.00e+00	2.895	2	6	277
GO:0034644	cellular response to UV	2.87e-02	1.00e+00	5.102	1	1	30
GO:0042130	negative regulation of T cell proliferation	2.87e-02	1.00e+00	5.102	1	1	30
GO:0060325	face morphogenesis	2.97e-02	1.00e+00	5.055	1	1	31
GO:0007093	mitotic cell cycle checkpoint	2.97e-02	1.00e+00	5.055	1	1	31
GO:0032320	positive regulation of Ras GTPase activity	3.06e-02	1.00e+00	5.009	1	1	32
GO:0032570	response to progesterone	3.06e-02	1.00e+00	5.009	1	1	32
GO:0043491	protein kinase B signaling	3.06e-02	1.00e+00	5.009	1	2	32
GO:0002062	chondrocyte differentiation	3.06e-02	1.00e+00	5.009	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.06e-02	1.00e+00	5.009	1	2	32
GO:0001837	epithelial to mesenchymal transition	3.16e-02	1.00e+00	4.964	1	2	33
GO:0001104	RNA polymerase II transcription cofactor activity	3.16e-02	1.00e+00	4.964	1	8	33
GO:0045599	negative regulation of fat cell differentiation	3.35e-02	1.00e+00	4.879	1	2	35
GO:0016592	mediator complex	3.35e-02	1.00e+00	4.879	1	10	35
GO:0042552	myelination	3.35e-02	1.00e+00	4.879	1	4	35
GO:0001933	negative regulation of protein phosphorylation	3.44e-02	1.00e+00	4.839	1	2	36
GO:0071560	cellular response to transforming growth factor beta stimulus	3.44e-02	1.00e+00	4.839	1	3	36
GO:0048839	inner ear development	3.53e-02	1.00e+00	4.799	1	1	37
GO:0042752	regulation of circadian rhythm	3.53e-02	1.00e+00	4.799	1	3	37
GO:0005902	microvillus	3.63e-02	1.00e+00	4.761	1	3	38
GO:0001657	ureteric bud development	3.63e-02	1.00e+00	4.761	1	2	38
GO:0031490	chromatin DNA binding	3.63e-02	1.00e+00	4.761	1	2	38
GO:0097191	extrinsic apoptotic signaling pathway	3.63e-02	1.00e+00	4.761	1	1	38
GO:0071407	cellular response to organic cyclic compound	3.63e-02	1.00e+00	4.761	1	3	38
GO:0045786	negative regulation of cell cycle	3.72e-02	1.00e+00	4.723	1	3	39
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.78e-02	1.00e+00	1.970	3	41	789
GO:0035019	somatic stem cell maintenance	3.82e-02	1.00e+00	4.687	1	6	40
GO:0070301	cellular response to hydrogen peroxide	3.91e-02	1.00e+00	4.651	1	2	41
GO:0031124	mRNA 3'-end processing	4.00e-02	1.00e+00	4.616	1	2	42
GO:0001047	core promoter binding	4.28e-02	1.00e+00	4.517	1	5	45
GO:0006369	termination of RNA polymerase II transcription	4.28e-02	1.00e+00	4.517	1	2	45
GO:0048511	rhythmic process	4.28e-02	1.00e+00	4.517	1	4	45
GO:0035064	methylated histone binding	4.38e-02	1.00e+00	4.485	1	2	46
GO:0031093	platelet alpha granule lumen	4.56e-02	1.00e+00	4.424	1	2	48
GO:0016049	cell growth	4.65e-02	1.00e+00	4.394	1	3	49
GO:0006521	regulation of cellular amino acid metabolic process	4.75e-02	1.00e+00	4.365	1	1	50
GO:0031100	organ regeneration	4.75e-02	1.00e+00	4.365	1	1	50
GO:0001948	glycoprotein binding	4.75e-02	1.00e+00	4.365	1	2	50
GO:0030334	regulation of cell migration	4.75e-02	1.00e+00	4.365	1	5	50
GO:0050680	negative regulation of epithelial cell proliferation	4.84e-02	1.00e+00	4.336	1	2	51
GO:0045216	cell-cell junction organization	5.12e-02	1.00e+00	4.254	1	2	54
GO:0002244	hematopoietic progenitor cell differentiation	5.12e-02	1.00e+00	4.254	1	1	54
GO:0050679	positive regulation of epithelial cell proliferation	5.12e-02	1.00e+00	4.254	1	2	54
GO:0008284	positive regulation of cell proliferation	5.16e-02	1.00e+00	2.431	2	10	382
GO:0000724	double-strand break repair via homologous recombination	5.21e-02	1.00e+00	4.227	1	2	55
GO:0000502	proteasome complex	5.49e-02	1.00e+00	4.151	1	3	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	5.58e-02	1.00e+00	4.126	1	2	59
GO:0006396	RNA processing	5.58e-02	1.00e+00	4.126	1	5	59
GO:0009986	cell surface	5.65e-02	1.00e+00	2.358	2	9	402
GO:0006406	mRNA export from nucleus	5.76e-02	1.00e+00	4.078	1	4	61
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	5.76e-02	1.00e+00	4.078	1	2	61
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.04e-02	1.00e+00	4.009	1	1	64
GO:0009749	response to glucose	6.04e-02	1.00e+00	4.009	1	7	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.13e-02	1.00e+00	3.986	1	2	65
GO:0006310	DNA recombination	6.13e-02	1.00e+00	3.986	1	7	65
GO:0010468	regulation of gene expression	6.40e-02	1.00e+00	3.921	1	2	68
GO:0006874	cellular calcium ion homeostasis	6.59e-02	1.00e+00	3.879	1	2	70
GO:0051897	positive regulation of protein kinase B signaling	6.59e-02	1.00e+00	3.879	1	2	70
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.59e-02	1.00e+00	3.879	1	2	70
GO:0032355	response to estradiol	6.68e-02	1.00e+00	3.859	1	3	71
GO:0000165	MAPK cascade	6.77e-02	1.00e+00	3.839	1	2	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.77e-02	1.00e+00	3.839	1	1	72
GO:0005796	Golgi lumen	6.77e-02	1.00e+00	3.839	1	3	72
GO:0002020	protease binding	6.95e-02	1.00e+00	3.799	1	6	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.95e-02	1.00e+00	3.799	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.95e-02	1.00e+00	3.799	1	2	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.04e-02	1.00e+00	3.780	1	1	75
GO:0010629	negative regulation of gene expression	7.22e-02	1.00e+00	3.742	1	4	77
GO:0071013	catalytic step 2 spliceosome	7.31e-02	1.00e+00	3.723	1	7	78
GO:0007565	female pregnancy	7.31e-02	1.00e+00	3.723	1	2	78
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.40e-02	1.00e+00	3.705	1	2	79
GO:0002576	platelet degranulation	7.68e-02	1.00e+00	3.651	1	2	82
GO:0009653	anatomical structure morphogenesis	7.77e-02	1.00e+00	3.634	1	2	83
GO:0009952	anterior/posterior pattern specification	7.77e-02	1.00e+00	3.634	1	4	83
GO:0044822	poly(A) RNA binding	7.77e-02	1.00e+00	1.549	3	50	1056
GO:0047485	protein N-terminus binding	8.04e-02	1.00e+00	3.582	1	3	86
GO:0050821	protein stabilization	8.21e-02	1.00e+00	3.549	1	3	88
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8.57e-02	1.00e+00	3.485	1	1	92
GO:0001649	osteoblast differentiation	8.57e-02	1.00e+00	3.485	1	5	92
GO:0016568	chromatin modification	9.11e-02	1.00e+00	3.394	1	4	98
GO:0001934	positive regulation of protein phosphorylation	9.64e-02	1.00e+00	3.308	1	5	104
GO:0042127	regulation of cell proliferation	1.01e-01	1.00e+00	3.241	1	4	109
GO:0030308	negative regulation of cell growth	1.02e-01	1.00e+00	3.227	1	6	110
GO:0030529	ribonucleoprotein complex	1.03e-01	1.00e+00	3.201	1	5	112
GO:0072562	blood microparticle	1.03e-01	1.00e+00	3.214	1	3	111
GO:0019058	viral life cycle	1.06e-01	1.00e+00	3.163	1	1	115
GO:0000209	protein polyubiquitination	1.07e-01	1.00e+00	3.151	1	3	116
GO:0007568	aging	1.08e-01	1.00e+00	3.138	1	2	117
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.14e-01	1.00e+00	3.055	1	5	124
GO:0007050	cell cycle arrest	1.14e-01	1.00e+00	3.055	1	5	124
GO:0007179	transforming growth factor beta receptor signaling pathway	1.17e-01	1.00e+00	3.009	1	11	128
GO:0030335	positive regulation of cell migration	1.17e-01	1.00e+00	3.020	1	5	127
GO:0000790	nuclear chromatin	1.18e-01	1.00e+00	2.998	1	6	129
GO:0005125	cytokine activity	1.26e-01	1.00e+00	2.900	1	2	138
GO:0008083	growth factor activity	1.29e-01	1.00e+00	2.869	1	3	141
GO:0005737	cytoplasm	1.32e-01	1.00e+00	0.714	6	124	3767
GO:0001666	response to hypoxia	1.35e-01	1.00e+00	2.790	1	7	149
GO:0000082	G1/S transition of mitotic cell cycle	1.35e-01	1.00e+00	2.790	1	3	149
GO:0042981	regulation of apoptotic process	1.36e-01	1.00e+00	2.780	1	4	150
GO:0005578	proteinaceous extracellular matrix	1.45e-01	1.00e+00	2.687	1	4	160
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.49e-01	1.00e+00	2.642	1	12	165
GO:0030424	axon	1.50e-01	1.00e+00	2.634	1	4	166
GO:0034641	cellular nitrogen compound metabolic process	1.54e-01	1.00e+00	2.591	1	2	171
GO:0016607	nuclear speck	1.55e-01	1.00e+00	2.582	1	12	172
GO:0007049	cell cycle	1.56e-01	1.00e+00	2.566	1	6	174
GO:0031625	ubiquitin protein ligase binding	1.60e-01	1.00e+00	2.533	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.65e-01	1.00e+00	2.485	1	22	184
GO:0007173	epidermal growth factor receptor signaling pathway	1.69e-01	1.00e+00	2.446	1	5	189
GO:0030168	platelet activation	1.82e-01	1.00e+00	2.329	1	6	205
GO:0016071	mRNA metabolic process	1.96e-01	1.00e+00	2.208	1	8	223
GO:0005730	nucleolus	2.08e-01	1.00e+00	0.913	3	66	1641
GO:0008134	transcription factor binding	2.11e-01	1.00e+00	2.090	1	18	242
GO:0016070	RNA metabolic process	2.15e-01	1.00e+00	2.060	1	8	247
GO:0016020	membrane	2.18e-01	1.00e+00	0.879	3	46	1681
GO:0000166	nucleotide binding	2.24e-01	1.00e+00	1.992	1	13	259
GO:0006281	DNA repair	2.26e-01	1.00e+00	1.981	1	14	261
GO:0007283	spermatogenesis	2.26e-01	1.00e+00	1.975	1	3	262
GO:0043065	positive regulation of apoptotic process	2.31e-01	1.00e+00	1.943	1	7	268
GO:0005743	mitochondrial inner membrane	2.38e-01	1.00e+00	1.895	1	6	277
GO:0019899	enzyme binding	2.38e-01	1.00e+00	1.895	1	9	277
GO:0030198	extracellular matrix organization	2.42e-01	1.00e+00	1.864	1	6	283
GO:0042493	response to drug	2.43e-01	1.00e+00	1.859	1	6	284
GO:0043234	protein complex	2.51e-01	1.00e+00	1.804	1	11	295
GO:0005739	mitochondrion	2.52e-01	1.00e+00	1.046	2	23	998
GO:0030154	cell differentiation	2.56e-01	1.00e+00	1.775	1	5	301
GO:0008283	cell proliferation	2.75e-01	1.00e+00	1.651	1	14	328
GO:0008285	negative regulation of cell proliferation	2.93e-01	1.00e+00	1.545	1	10	353
GO:0046982	protein heterodimerization activity	3.12e-01	1.00e+00	1.439	1	8	380
GO:0000278	mitotic cell cycle	3.20e-01	1.00e+00	1.398	1	15	391
GO:0043066	negative regulation of apoptotic process	3.42e-01	1.00e+00	1.281	1	16	424
GO:0007596	blood coagulation	3.62e-01	1.00e+00	1.179	1	11	455
GO:0006468	protein phosphorylation	3.65e-01	1.00e+00	1.163	1	10	460
GO:0046872	metal ion binding	3.67e-01	1.00e+00	0.657	2	29	1307
GO:0045893	positive regulation of transcription, DNA-templated	3.76e-01	1.00e+00	1.108	1	24	478
GO:0042802	identical protein binding	3.80e-01	1.00e+00	1.090	1	19	484
GO:0016032	viral process	4.10e-01	1.00e+00	0.948	1	26	534
GO:0006915	apoptotic process	4.23e-01	1.00e+00	0.892	1	12	555
GO:0042803	protein homodimerization activity	4.46e-01	1.00e+00	0.792	1	19	595
GO:0005829	cytosol	4.47e-01	1.00e+00	0.308	3	86	2496
GO:0005576	extracellular region	6.12e-01	1.00e+00	0.129	1	13	942
GO:0005615	extracellular space	6.18e-01	1.00e+00	0.106	1	20	957
GO:0008270	zinc ion binding	6.33e-01	1.00e+00	0.047	1	27	997
GO:0070062	extracellular vesicular exosome	7.03e-01	1.00e+00	-0.220	2	57	2400
GO:0044281	small molecule metabolic process	7.07e-01	1.00e+00	-0.233	1	20	1211
GO:0005524	ATP binding	7.33e-01	1.00e+00	-0.333	1	31	1298
GO:0005886	plasma membrane	9.37e-01	1.00e+00	-1.326	1	49	2582

chia-Fav

int-snw-121536

Statistics

Genes (14)

Interactions (15)

Related GO terms (341)