meta-int-snw-1120

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-2982 wolf-screen-ratio-mammosphere-adherent 0.807 2.02e-06 4.38e-03 7.98e-03 7 6
int-snw-1120 wolf-screen-ratio-mammosphere-adherent 0.934 1.80e-15 2.53e-03 4.08e-02 16 15
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-5887 wolf-screen-ratio-mammosphere-adherent 0.858 2.95e-07 1.57e-03 3.19e-03 5 5
reg-snw-5905 wolf-screen-ratio-mammosphere-adherent 0.816 1.47e-06 3.71e-03 6.88e-03 6 6
reg-snw-158 wolf-screen-ratio-mammosphere-adherent 0.934 1.18e-08 2.65e-04 6.55e-04 9 8
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1478 wolf-screen-ratio-mammosphere-adherent 0.940 8.80e-09 2.25e-04 5.65e-04 7 7
reg-snw-2237 wolf-screen-ratio-mammosphere-adherent 0.894 6.72e-08 6.99e-04 1.55e-03 9 8
reg-snw-6723 wolf-screen-ratio-mammosphere-adherent 0.840 5.77e-07 2.25e-03 4.41e-03 13 11
reg-snw-10459 wolf-screen-ratio-mammosphere-adherent 0.798 2.82e-06 5.23e-03 9.35e-03 7 6
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-1120 subnetwork

Genes (45)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
SRM 6723 13-0.0640.84032--
PSMA2 5683 1121.0931.106108Yes-
PHB2 11331 430.8290.956151Yes-
POLR2F 5435 620.8910.95626Yes-
VARS 7407 860.5491.002204Yes-
CHKB 1120 12-0.1690.93442-Yes
ATP6V1B2 526 530.8811.076278--
DDX51 317781 530.0590.823210Yes-
MAD2L2 10459 60.2700.79821Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
EIF2S2 8894 391.0750.940103Yes-
EEF2 1938 640.8901.043301Yes-
RAD23B 5887 70.1580.85811Yes-
EFTUD2 9343 930.8830.956108Yes-
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
FBL 2091 420.8390.95679Yes-
PRMT3 10196 490.4310.81526--
FEN1 2237 100.0140.89489--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
POLA1 5422 170.5930.894114Yes-
PSMC3 5702 510.7191.002276Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
E2F3 1871 6-0.4130.79833--
ADSL 158 150.1070.93426--
PSMA1 5682 1000.9960.878152Yes-
RANGAP1 5905 11-0.0460.81674Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
PGD 5226 891.2011.106152Yes-
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
CSTF2 1478 10-0.0500.94098-Yes
GSK3B 2932 220.4750.934319-Yes
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
GUCY1A3 2982 70.0280.80719--

Interactions (167)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
ATP6V1B2 526 DDX51 317781 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
FEN1 2237 RUVBL1 8607 pd < reg.ITFP.txt: no annot
EEF2 1938 PSMC3 5702 pp -- int.I2D: YeastLow, BioGrid_Yeast
PSMB2 5690 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
EEF2 1938 PSMB3 5691 pp -- int.I2D: IntAct_Fly, BioGrid_Fly, BIND_Fly, FlyLow, MINT_Fly
EEF2 1938 DDX51 317781 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 RAD23B 5887 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
PSMC3 5702 VARS 7407 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB7 5695 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, MIPS
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMC3 5702 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMD3 5709 RAD23B 5887 pd > reg.ITFP.txt: no annot
PSMD3 5709 RAD23B 5887 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
SRM 6723 RUVBL1 8607 pd < reg.ITFP.txt: no annot
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMC3 5702 PSMD3 5709 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
EIF6 3692 PGD 5226 pp -- int.I2D: YeastLow
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
GSK3B 2932 TUBG1 7283 pp -- int.I2D: MINT
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
FEN1 2237 PSMD11 5717 pd < reg.ITFP.txt: no annot
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
SRM 6723 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ADSL 158 CAD 790 pp -- int.I2D: YeastLow
ATP6V1B2 526 CHKB 1120 pp -- int.I2D: IntAct_Yeast
CHKB 1120 PSMD3 5709 pp -- int.I2D: IntAct_Yeast
CHKB 1120 GSK3B 2932 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
EEF2 1938 RAD23B 5887 pp -- int.I2D: Krogan_NonCore
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPSA 3921 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RPSA 3921 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
FBL 2091 PRMT3 10196 pp -- int.I2D: BioGrid
ATP6V1B2 526 SRM 6723 pp -- int.I2D: IntAct_Yeast
FEN1 2237 RPA1 6117 pd < reg.ITFP.txt: no annot
FEN1 2237 RPA1 6117 pp -- int.I2D: BioGrid_Yeast
ADSL 158 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
FEN1 2237 GSK3B 2932 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
EEF2 1938 RPA1 6117 pp -- int.I2D: YeastLow, Krogan_NonCore
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
ADSL 158 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
E2F3 1871 MAD2L2 10459 pd > reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
CSTF2 1478 FEN1 2237 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 MAD2L2 10459 pd > reg.ITFP.txt: no annot
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
CAD 790 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
ACTB 60 FBL 2091 pp -- int.I2D: MINT
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
CSTF2 1478 EFTUD2 9343 pd > reg.ITFP.txt: no annot
EEF2 1938 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
SRM 6723 VARS 7407 pd < reg.ITFP.txt: no annot
SRM 6723 VARS 7407 pp -- int.I2D: YeastLow
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
EIF6 3692 SRM 6723 pp -- int.I2D: YeastLow
FBL 2091 RUVBL1 8607 pp -- int.I2D: BioGrid
POLA1 5422 RPA1 6117 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
FEN1 2237 DDX51 317781 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMD3 5709 RANGAP1 5905 pd > reg.ITFP.txt: no annot
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
PSMC3 5702 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ADSL 158 RBX1 9978 pd < reg.ITFP.txt: no annot
ACTB 60 RAD23B 5887 pp -- int.I2D: IntAct_Rat
PSMC3 5702 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, IntAct_Rat, Krogan_Core, MINT_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
FBL 2091 RUVBL2 10856 pd < reg.ITFP.txt: no annot
FBL 2091 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RANGAP1 5905 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
CAD 790 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
FEN1 2237 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast
RANGAP1 5905 VARS 7407 pd < reg.ITFP.txt: no annot
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
FEN1 2237 POLA1 5422 pd < reg.ITFP.txt: no annot
ADSL 158 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
GSK3B 2932 EFTUD2 9343 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
SRM 6723 DDX51 317781 pd < reg.ITFP.txt: no annot
GUCY1A3 2982 PSMD11 5717 pd < reg.ITFP.txt: no annot
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 ADSL 158 pp -- int.I2D: BioGrid_Yeast
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ATP6V1B2 526 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 RAD23B 5887 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, BIND_Yeast, MINT_Yeast, MIPS
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RUVBL2 10856 PHB2 11331 pd > reg.ITFP.txt: no annot
RUVBL2 10856 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (564)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm8.16e-161.33e-112.92923831095
GO:0000502proteasome complex3.79e-146.18e-105.81592258
GO:0000278mitotic cell cycle8.74e-141.43e-093.7731552398
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.12e-131.83e-095.65092465
GO:0005829cytosol2.00e-133.27e-092.038291252562
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.26e-133.69e-095.54392470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.81e-136.22e-095.46392474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process7.02e-131.15e-085.36992579
GO:0006521regulation of cellular amino acid metabolic process8.53e-131.39e-085.85982150
GO:0000082G1/S transition of mitotic cell cycle7.70e-121.26e-074.5961033150
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest7.78e-121.27e-075.48082265
GO:0010467gene expression1.13e-111.85e-073.1171658669
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.04e-113.33e-075.31382373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.17e-115.17e-075.23682377
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.62e-102.64e-064.94882394
GO:0000209protein polyubiquitination8.83e-101.44e-054.645821116
GO:0005839proteasome core complex1.06e-091.72e-056.65551118
GO:0034641cellular nitrogen compound metabolic process1.07e-091.75e-054.205925177
GO:0004298threonine-type endopeptidase activity1.90e-093.11e-056.50351120
GO:0042981regulation of apoptotic process7.19e-091.17e-044.264826151
GO:0016071mRNA metabolic process8.17e-091.33e-043.872934223
GO:0016032viral process1.62e-082.64e-043.0111255540
GO:0016070RNA metabolic process1.98e-083.24e-043.724934247
GO:0006281DNA repair3.52e-085.75e-043.628922264
GO:0005730nucleolus1.79e-072.93e-031.95518701684
GO:0070062extracellular vesicular exosome7.14e-071.17e-021.59821982516
GO:0005515protein binding1.12e-061.83e-020.966331726127
GO:0005634nucleus1.33e-062.18e-021.123291314828
GO:0016020membrane1.71e-062.79e-021.82017801746
GO:0043066negative regulation of apoptotic process2.28e-063.71e-022.914930433
GO:0016363nuclear matrix5.21e-068.51e-024.30151192
GO:0044281small molecule metabolic process5.86e-069.56e-021.97114571295
GO:0035267NuA4 histone acetyltransferase complex6.98e-061.14e-016.2803414
GO:0003684damaged DNA binding1.15e-051.87e-014.83041151
GO:0022624proteasome accessory complex1.30e-052.12e-016.0003917
GO:0030529ribonucleoprotein complex1.49e-052.43e-013.99258114
GO:0032201telomere maintenance via semi-conservative replication2.91e-054.75e-015.6283722
GO:0000722telomere maintenance via recombination4.87e-057.95e-015.3873726
GO:0006271DNA strand elongation involved in DNA replication8.34e-051.00e+005.1333931
GO:0006915apoptotic process1.47e-041.00e+002.345834571
GO:0019773proteasome core complex, alpha-subunit complex2.06e-041.00e+006.503258
GO:0000812Swr1 complex2.06e-041.00e+006.503238
GO:0006164purine nucleotide biosynthetic process2.06e-041.00e+006.503228
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding4.40e-041.00e+004.3333554
GO:0005838proteasome regulatory particle4.82e-041.00e+005.9182712
GO:0043968histone H2A acetylation4.82e-041.00e+005.9182312
GO:0000723telomere maintenance5.72e-041.00e+004.2053859
GO:0006302double-strand break repair6.61e-041.00e+004.1333862
GO:0031011Ino80 complex6.62e-041.00e+005.6952314
GO:0006310DNA recombination8.29e-041.00e+004.0213467
GO:0005524ATP binding8.93e-041.00e+001.55911461354
GO:0006289nucleotide-excision repair9.04e-041.00e+003.97931269
GO:0000398mRNA splicing, via spliceosome1.09e-031.00e+003.136412165
GO:0003678DNA helicase activity1.23e-031.00e+005.2552319
GO:0043234protein complex1.36e-031.00e+002.596517300
GO:0005680anaphase-promoting complex1.37e-031.00e+005.1812420
GO:0000718nucleotide-excision repair, DNA damage removal1.51e-031.00e+005.1102521
GO:0006297nucleotide-excision repair, DNA gap filling1.66e-031.00e+005.0432522
GO:0019901protein kinase binding1.80e-031.00e+002.503521320
GO:0043044ATP-dependent chromatin remodeling1.81e-031.00e+004.9792423
GO:0005844polysome2.14e-031.00e+004.8592425
GO:0001649osteoblast differentiation2.27e-031.00e+003.5183695
GO:0044822poly(A) RNA binding2.36e-031.00e+001.5989501078
GO:0071339MLL1 complex2.50e-031.00e+004.7482327
GO:0043022ribosome binding2.68e-031.00e+004.6952328
GO:0043967histone H4 acetylation2.68e-031.00e+004.6952328
GO:0031492nucleosomal DNA binding2.68e-031.00e+004.6952428
GO:0042772DNA damage response, signal transduction resulting in transcription2.76e-031.00e+008.503111
GO:0008309double-stranded DNA exodeoxyribonuclease activity2.76e-031.00e+008.503111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.76e-031.00e+008.503111
GO:0070626(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity2.76e-031.00e+008.503111
GO:0019521D-gluconate metabolic process2.76e-031.00e+008.503111
GO:0005098Ran GTPase activator activity2.76e-031.00e+008.503111
GO:0016074snoRNA metabolic process2.76e-031.00e+008.503111
GO:0070335aspartate binding2.76e-031.00e+008.503111
GO:1990259histone-glutamine methyltransferase activity2.76e-031.00e+008.503111
GO:0052565response to defense-related host nitric oxide production2.76e-031.00e+008.503111
GO:0004018N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity2.76e-031.00e+008.503111
GO:1990258histone glutamine methylation2.76e-031.00e+008.503111
GO:0004151dihydroorotase activity2.76e-031.00e+008.503111
GO:0000054ribosomal subunit export from nucleus2.76e-031.00e+008.503111
GO:0004070aspartate carbamoyltransferase activity2.76e-031.00e+008.503111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.76e-031.00e+008.503111
GO:0003723RNA binding2.83e-031.00e+002.353519355
GO:0003887DNA-directed DNA polymerase activity2.88e-031.00e+004.6452329
GO:0007094mitotic spindle assembly checkpoint3.29e-031.00e+004.5482531
GO:0033572transferrin transport3.50e-031.00e+004.5032632
GO:0007067mitotic nuclear division3.70e-031.00e+002.651413231
GO:0008380RNA splicing3.75e-031.00e+002.645413232
GO:0005819spindle3.80e-031.00e+003.25537114
GO:0006325chromatin organization4.71e-031.00e+003.14534123
GO:0006260DNA replication4.92e-031.00e+003.122312125
GO:0006284base-excision repair5.16e-031.00e+004.2172739
GO:0006272leading strand elongation5.51e-031.00e+007.503122
GO:0006407rRNA export from nucleus5.51e-031.00e+007.503112
GO:0004766spermidine synthase activity5.51e-031.00e+007.503112
GO:0071109superior temporal gyrus development5.51e-031.00e+007.503112
GO:2000077negative regulation of type B pancreatic cell development5.51e-031.00e+007.503112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.51e-031.00e+007.503112
GO:0019322pentose biosynthetic process5.51e-031.00e+007.503112
GO:0004832valine-tRNA ligase activity5.51e-031.00e+007.503112
GO:0008074guanylate cyclase complex, soluble5.51e-031.00e+007.503112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process5.51e-031.00e+007.503122
GO:0002176male germ cell proliferation5.51e-031.00e+007.503112
GO:0004103choline kinase activity5.51e-031.00e+007.503112
GO:0000715nucleotide-excision repair, DNA damage recognition5.51e-031.00e+007.503112
GO:0006438valyl-tRNA aminoacylation5.51e-031.00e+007.503112
GO:0071920cleavage body5.51e-031.00e+007.503112
GO:0000105histidine biosynthetic process5.51e-031.00e+007.503112
GO:0008295spermidine biosynthetic process5.51e-031.00e+007.503112
GO:0005055laminin receptor activity5.51e-031.00e+007.503112
GO:0070409carbamoyl phosphate biosynthetic process5.51e-031.00e+007.503112
GO:0016035zeta DNA polymerase complex5.51e-031.00e+007.503112
GO:0006413translational initiation5.61e-031.00e+003.054312131
GO:0032508DNA duplex unwinding5.97e-031.00e+004.1102442
GO:0015030Cajal body6.83e-031.00e+004.0112245
GO:0006283transcription-coupled nucleotide-excision repair7.12e-031.00e+003.9792846
GO:0016887ATPase activity7.28e-031.00e+002.91837144
GO:0003743translation initiation factor activity8.05e-031.00e+003.8882449
GO:0060564negative regulation of mitotic anaphase-promoting complex activity8.25e-031.00e+006.918113
GO:0014043negative regulation of neuron maturation8.25e-031.00e+006.918113
GO:0000320re-entry into mitotic cell cycle8.25e-031.00e+006.918113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity8.25e-031.00e+006.918113
GO:2000466negative regulation of glycogen (starch) synthase activity8.25e-031.00e+006.918113
GO:1900126negative regulation of hyaluronan biosynthetic process8.25e-031.00e+006.918113
GO:0009051pentose-phosphate shunt, oxidative branch8.25e-031.00e+006.918113
GO:0044205'de novo' UMP biosynthetic process8.25e-031.00e+006.918113
GO:0071942XPC complex8.25e-031.00e+006.918113
GO:0071899negative regulation of estrogen receptor binding8.25e-031.00e+006.918113
GO:0005850eukaryotic translation initiation factor 2 complex8.25e-031.00e+006.918113
GO:0071733transcriptional activation by promoter-enhancer looping8.25e-031.00e+006.918113
GO:0044027hypermethylation of CpG island8.25e-031.00e+006.918113
GO:0044208'de novo' AMP biosynthetic process8.25e-031.00e+006.918113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process8.25e-031.00e+006.918113
GO:0071439clathrin complex8.25e-031.00e+006.918113
GO:0040008regulation of growth8.70e-031.00e+003.8302351
GO:0000932cytoplasmic mRNA processing body1.04e-021.00e+003.6952356
GO:003068690S preribosome1.10e-021.00e+006.503114
GO:0004305ethanolamine kinase activity1.10e-021.00e+006.503114
GO:0043137DNA replication, removal of RNA primer1.10e-021.00e+006.503114
GO:0019788NEDD8 ligase activity1.10e-021.00e+006.503114
GO:0001652granular component1.10e-021.00e+006.503114
GO:0016274protein-arginine N-methyltransferase activity1.10e-021.00e+006.503114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity1.10e-021.00e+006.503114
GO:0031428box C/D snoRNP complex1.10e-021.00e+006.503114
GO:0004329formate-tetrahydrofolate ligase activity1.10e-021.00e+006.503114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.10e-021.00e+006.503114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity1.10e-021.00e+006.503114
GO:0051534negative regulation of NFAT protein import into nucleus1.10e-021.00e+006.503114
GO:0006273lagging strand elongation1.10e-021.00e+006.503114
GO:0003896DNA primase activity1.10e-021.00e+006.503124
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.10e-021.00e+006.503114
GO:0000212meiotic spindle organization1.10e-021.00e+006.503114
GO:0005658alpha DNA polymerase:primase complex1.10e-021.00e+006.503114
GO:0032051clathrin light chain binding1.10e-021.00e+006.503114
GO:2000048negative regulation of cell-cell adhesion mediated by cadherin1.10e-021.00e+006.503114
GO:0006167AMP biosynthetic process1.10e-021.00e+006.503114
GO:0034969histone arginine methylation1.10e-021.00e+006.503114
GO:0006543glutamine catabolic process1.10e-021.00e+006.503114
GO:0009396folic acid-containing compound biosynthetic process1.10e-021.00e+006.503114
GO:0031467Cul7-RING ubiquitin ligase complex1.10e-021.00e+006.503114
GO:1903077negative regulation of protein localization to plasma membrane1.10e-021.00e+006.503114
GO:0033138positive regulation of peptidyl-serine phosphorylation1.23e-021.00e+003.5722361
GO:0005525GTP binding1.25e-021.00e+002.145411328
GO:0042256mature ribosome assembly1.37e-021.00e+006.181115
GO:0001882nucleoside binding1.37e-021.00e+006.181115
GO:0006269DNA replication, synthesis of RNA primer1.37e-021.00e+006.181125
GO:0043248proteasome assembly1.37e-021.00e+006.181115
GO:0036016cellular response to interleukin-31.37e-021.00e+006.181115
GO:0030891VCB complex1.37e-021.00e+006.181125
GO:00171085'-flap endonuclease activity1.37e-021.00e+006.181115
GO:0005827polar microtubule1.37e-021.00e+006.181115
GO:0004523RNA-DNA hybrid ribonuclease activity1.37e-021.00e+006.181115
GO:0051414response to cortisol1.37e-021.00e+006.181115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.37e-021.00e+006.181125
GO:0009086methionine biosynthetic process1.37e-021.00e+006.181115
GO:0008622epsilon DNA polymerase complex1.37e-021.00e+006.181115
GO:0031461cullin-RING ubiquitin ligase complex1.37e-021.00e+006.181115
GO:0071169establishment of protein localization to chromatin1.37e-021.00e+006.181115
GO:2000738positive regulation of stem cell differentiation1.37e-021.00e+006.181115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.37e-021.00e+006.181115
GO:0000730DNA recombinase assembly1.37e-021.00e+006.181135
GO:0005638lamin filament1.37e-021.00e+006.181115
GO:0005813centrosome1.40e-021.00e+002.097412339
GO:0005737cytoplasm1.46e-021.00e+000.71518983976
GO:0003697single-stranded DNA binding1.55e-021.00e+003.3942969
GO:0030118clathrin coat1.64e-021.00e+005.918116
GO:0030828positive regulation of cGMP biosynthetic process1.64e-021.00e+005.918116
GO:0046134pyrimidine nucleoside biosynthetic process1.64e-021.00e+005.918116
GO:0032853positive regulation of Ran GTPase activity1.64e-021.00e+005.918116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis1.64e-021.00e+005.918116
GO:0010614negative regulation of cardiac muscle hypertrophy1.64e-021.00e+005.918116
GO:0030130clathrin coat of trans-Golgi network vesicle1.64e-021.00e+005.918116
GO:0006189'de novo' IMP biosynthetic process1.64e-021.00e+005.918116
GO:0060744mammary gland branching involved in thelarche1.64e-021.00e+005.918116
GO:0043023ribosomal large subunit binding1.64e-021.00e+005.918126
GO:0031466Cul5-RING ubiquitin ligase complex1.64e-021.00e+005.918116
GO:0050774negative regulation of dendrite morphogenesis1.64e-021.00e+005.918116
GO:0008432JUN kinase binding1.64e-021.00e+005.918116
GO:0030957Tat protein binding1.64e-021.00e+005.918146
GO:0008469histone-arginine N-methyltransferase activity1.64e-021.00e+005.918116
GO:0055086nucleobase-containing small molecule metabolic process1.73e-021.00e+003.3132573
GO:0003924GTPase activity1.83e-021.00e+002.42239203
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.86e-021.00e+003.2552376
GO:0031462Cul2-RING ubiquitin ligase complex1.91e-021.00e+005.695127
GO:0060087relaxation of vascular smooth muscle1.91e-021.00e+005.695117
GO:0035999tetrahydrofolate interconversion1.91e-021.00e+005.695117
GO:0046826negative regulation of protein export from nucleus1.91e-021.00e+005.695117
GO:0000028ribosomal small subunit assembly1.91e-021.00e+005.695117
GO:0002161aminoacyl-tRNA editing activity1.91e-021.00e+005.695127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.91e-021.00e+005.695117
GO:0006657CDP-choline pathway1.91e-021.00e+005.695117
GO:0033180proton-transporting V-type ATPase, V1 domain1.91e-021.00e+005.695127
GO:0030132clathrin coat of coated pit1.91e-021.00e+005.695117
GO:0072341modified amino acid binding1.91e-021.00e+005.695117
GO:0000930gamma-tubulin complex1.91e-021.00e+005.695117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.91e-021.00e+005.695117
GO:0071013catalytic step 2 spliceosome2.00e-021.00e+003.1992779
GO:0045116protein neddylation2.19e-021.00e+005.503128
GO:0000800lateral element2.19e-021.00e+005.503118
GO:0045719negative regulation of glycogen biosynthetic process2.19e-021.00e+005.503118
GO:0031464Cul4A-RING E3 ubiquitin ligase complex2.19e-021.00e+005.503128
GO:0001055RNA polymerase II activity2.19e-021.00e+005.503138
GO:0004383guanylate cyclase activity2.19e-021.00e+005.503118
GO:0070688MLL5-L complex2.19e-021.00e+005.503118
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway2.19e-021.00e+005.503118
GO:0035372protein localization to microtubule2.19e-021.00e+005.503118
GO:0005681spliceosomal complex2.20e-021.00e+003.1282383
GO:0006184GTP catabolic process2.26e-021.00e+002.30639220
GO:00084095'-3' exonuclease activity2.45e-021.00e+005.333119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.45e-021.00e+005.333119
GO:0032434regulation of proteasomal ubiquitin-dependent protein catabolic process2.45e-021.00e+005.333119
GO:0006983ER overload response2.45e-021.00e+005.333129
GO:0014075response to amine2.45e-021.00e+005.333119
GO:0008494translation activator activity2.45e-021.00e+005.333119
GO:0048156tau protein binding2.45e-021.00e+005.333119
GO:0006228UTP biosynthetic process2.45e-021.00e+005.333119
GO:0090090negative regulation of canonical Wnt signaling pathway2.45e-021.00e+003.0432388
GO:0031000response to caffeine2.45e-021.00e+005.333129
GO:0042470melanosome2.66e-021.00e+002.97921092
GO:0006412translation2.68e-021.00e+002.211315235
GO:0005200structural constituent of cytoskeleton2.71e-021.00e+002.9632793
GO:0006414translational elongation2.71e-021.00e+002.96321193
GO:0046655folic acid metabolic process2.72e-021.00e+005.1811110
GO:0006379mRNA cleavage2.72e-021.00e+005.1811110
GO:0006450regulation of translational fidelity2.72e-021.00e+005.1811210
GO:0010226response to lithium ion2.72e-021.00e+005.1811210
GO:0000731DNA synthesis involved in DNA repair2.72e-021.00e+005.1811110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway2.72e-021.00e+005.1811110
GO:0010944negative regulation of transcription by competitive promoter binding2.72e-021.00e+005.1811110
GO:0030877beta-catenin destruction complex2.72e-021.00e+005.1811210
GO:0006364rRNA processing2.88e-021.00e+002.9182596
GO:0045120pronucleus2.99e-021.00e+005.0431111
GO:0006098pentose-phosphate shunt2.99e-021.00e+005.0431311
GO:0001054RNA polymerase I activity2.99e-021.00e+005.0431311
GO:0009168purine ribonucleoside monophosphate biosynthetic process3.26e-021.00e+004.9181112
GO:0009650UV protection3.26e-021.00e+004.9181112
GO:00709353'-UTR-mediated mRNA stabilization3.26e-021.00e+004.9181212
GO:0005736DNA-directed RNA polymerase I complex3.26e-021.00e+004.9181312
GO:0019985translesion synthesis3.26e-021.00e+004.9181212
GO:0032886regulation of microtubule-based process3.26e-021.00e+004.9181412
GO:0034236protein kinase A catalytic subunit binding3.26e-021.00e+004.9181112
GO:0050321tau-protein kinase activity3.26e-021.00e+004.9181112
GO:0046827positive regulation of protein export from nucleus3.53e-021.00e+004.8021213
GO:0042273ribosomal large subunit biogenesis3.53e-021.00e+004.8021413
GO:0006646phosphatidylethanolamine biosynthetic process3.53e-021.00e+004.8021213
GO:0005662DNA replication factor A complex3.53e-021.00e+004.8021313
GO:0030234enzyme regulator activity3.53e-021.00e+004.8021313
GO:0000738DNA catabolic process, exonucleolytic3.53e-021.00e+004.8021213
GO:0008266poly(U) RNA binding3.53e-021.00e+004.8021113
GO:0031333negative regulation of protein complex assembly3.79e-021.00e+004.6951114
GO:2000678negative regulation of transcription regulatory region DNA binding3.79e-021.00e+004.6951114
GO:0048168regulation of neuronal synaptic plasticity3.79e-021.00e+004.6951114
GO:0006595polyamine metabolic process3.79e-021.00e+004.6951114
GO:0004527exonuclease activity3.79e-021.00e+004.6951114
GO:0007020microtubule nucleation3.79e-021.00e+004.6951114
GO:0031334positive regulation of protein complex assembly3.79e-021.00e+004.6951214
GO:0000166nucleotide binding3.89e-021.00e+002.00036272
GO:0006349regulation of gene expression by genetic imprinting4.06e-021.00e+004.5961115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex4.06e-021.00e+004.5961115
GO:0046961proton-transporting ATPase activity, rotational mechanism4.06e-021.00e+004.5961315
GO:0060749mammary gland alveolus development4.06e-021.00e+004.5961115
GO:0035066positive regulation of histone acetylation4.06e-021.00e+004.5961115
GO:0006182cGMP biosynthetic process4.06e-021.00e+004.5961115
GO:0006261DNA-dependent DNA replication4.06e-021.00e+004.5961215
GO:0050998nitric-oxide synthase binding4.32e-021.00e+004.5031116
GO:0001056RNA polymerase III activity4.32e-021.00e+004.5031316
GO:0042176regulation of protein catabolic process4.32e-021.00e+004.5031316
GO:0007520myoblast fusion4.32e-021.00e+004.5031116
GO:0005665DNA-directed RNA polymerase II, core complex4.32e-021.00e+004.5031416
GO:0046034ATP metabolic process4.32e-021.00e+004.5031116
GO:0001673male germ cell nucleus4.32e-021.00e+004.5031116
GO:00084083'-5' exonuclease activity4.32e-021.00e+004.5031216
GO:0035255ionotropic glutamate receptor binding4.59e-021.00e+004.4151117
GO:0003746translation elongation factor activity4.59e-021.00e+004.4151317
GO:0007263nitric oxide mediated signal transduction4.59e-021.00e+004.4151217
GO:0010243response to organonitrogen compound4.59e-021.00e+004.4151217
GO:0005666DNA-directed RNA polymerase III complex4.59e-021.00e+004.4151317
GO:0007126meiotic nuclear division4.59e-021.00e+004.4151117
GO:0007219Notch signaling pathway4.65e-021.00e+002.53724125
GO:0044267cellular protein metabolic process4.69e-021.00e+001.551424495
GO:0071392cellular response to estradiol stimulus4.85e-021.00e+004.3331118
GO:0031122cytoplasmic microtubule organization4.85e-021.00e+004.3331218
GO:0010800positive regulation of peptidyl-threonine phosphorylation4.85e-021.00e+004.3331118
GO:0006386termination of RNA polymerase III transcription4.85e-021.00e+004.3331318
GO:0006541glutamine metabolic process4.85e-021.00e+004.3331118
GO:0006385transcription elongation from RNA polymerase III promoter4.85e-021.00e+004.3331318
GO:0006303double-strand break repair via nonhomologous end joining4.85e-021.00e+004.3331318
GO:0006200ATP catabolic process5.07e-021.00e+001.844314303
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.11e-021.00e+004.2551119
GO:0007088regulation of mitosis5.11e-021.00e+004.2551119
GO:1903506regulation of nucleic acid-templated transcription5.11e-021.00e+004.2551119
GO:0048863stem cell differentiation5.11e-021.00e+004.2551119
GO:0000790nuclear chromatin5.20e-021.00e+002.44727133
GO:0015078hydrogen ion transmembrane transporter activity5.38e-021.00e+004.1811320
GO:0048873homeostasis of number of cells within a tissue5.38e-021.00e+004.1811120
GO:0005719nuclear euchromatin5.38e-021.00e+004.1811220
GO:0006298mismatch repair5.38e-021.00e+004.1811620
GO:0071364cellular response to epidermal growth factor stimulus5.64e-021.00e+004.1101121
GO:0010719negative regulation of epithelial to mesenchymal transition5.64e-021.00e+004.1101121
GO:0001954positive regulation of cell-matrix adhesion5.64e-021.00e+004.1101121
GO:0030010establishment of cell polarity5.64e-021.00e+004.1101221
GO:0033574response to testosterone5.90e-021.00e+004.0431222
GO:0006378mRNA polyadenylation5.90e-021.00e+004.0431122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle5.90e-021.00e+004.0431322
GO:0006656phosphatidylcholine biosynthetic process5.90e-021.00e+004.0431322
GO:0030863cortical cytoskeleton5.90e-021.00e+004.0431122
GO:0036464cytoplasmic ribonucleoprotein granule5.90e-021.00e+004.0431422
GO:0006270DNA replication initiation5.90e-021.00e+004.0431522
GO:0061024membrane organization6.13e-021.00e+002.31325146
GO:0031593polyubiquitin binding6.16e-021.00e+003.9791123
GO:0031463Cul3-RING ubiquitin ligase complex6.16e-021.00e+003.9791223
GO:0043236laminin binding6.16e-021.00e+003.9791123
GO:0006513protein monoubiquitination6.16e-021.00e+003.9791123
GO:0043231intracellular membrane-bounded organelle6.33e-021.00e+001.71338332
GO:0006457protein folding6.35e-021.00e+002.28328149
GO:0008135translation factor activity, nucleic acid binding6.42e-021.00e+003.9181424
GO:0000794condensed nuclear chromosome6.42e-021.00e+003.9181224
GO:0006206pyrimidine nucleobase metabolic process6.42e-021.00e+003.9181224
GO:0005977glycogen metabolic process6.42e-021.00e+003.9181124
GO:0006611protein export from nucleus6.67e-021.00e+003.8591425
GO:0051059NF-kappaB binding6.67e-021.00e+003.8591325
GO:0017144drug metabolic process6.67e-021.00e+003.8591125
GO:0070979protein K11-linked ubiquitination6.93e-021.00e+003.8021326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.93e-021.00e+003.8021226
GO:0004519endonuclease activity6.93e-021.00e+003.8021126
GO:0006730one-carbon metabolic process6.93e-021.00e+003.8021126
GO:0004003ATP-dependent DNA helicase activity7.19e-021.00e+003.7481327
GO:0034080CENP-A containing nucleosome assembly7.19e-021.00e+003.7481227
GO:0030331estrogen receptor binding7.19e-021.00e+003.7481227
GO:0015991ATP hydrolysis coupled proton transport7.45e-021.00e+003.6951428
GO:0019894kinesin binding7.45e-021.00e+003.6951128
GO:0019005SCF ubiquitin ligase complex7.70e-021.00e+003.6451129
GO:0003730mRNA 3'-UTR binding7.70e-021.00e+003.6451229
GO:0071897DNA biosynthetic process7.70e-021.00e+003.6451229
GO:0043198dendritic shaft7.70e-021.00e+003.6451129
GO:0030669clathrin-coated endocytic vesicle membrane7.70e-021.00e+003.6451129
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding7.82e-021.00e+002.11025168
GO:0051262protein tetramerization7.96e-021.00e+003.5961330
GO:0006360transcription from RNA polymerase I promoter7.96e-021.00e+003.5961430
GO:00063707-methylguanosine mRNA capping7.96e-021.00e+003.5961430
GO:0042177negative regulation of protein catabolic process7.96e-021.00e+003.5961130
GO:0031623receptor internalization8.21e-021.00e+003.5481131
GO:0050661NADP binding8.46e-021.00e+003.5031132
GO:0034644cellular response to UV8.46e-021.00e+003.5031532
GO:1903507negative regulation of nucleic acid-templated transcription8.46e-021.00e+003.5031232
GO:0006144purine nucleobase metabolic process8.46e-021.00e+003.5031232
GO:0031397negative regulation of protein ubiquitination8.46e-021.00e+003.5031132
GO:0015992proton transport8.46e-021.00e+003.5031332
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic8.46e-021.00e+003.5031132
GO:0032091negative regulation of protein binding8.72e-021.00e+003.4581133
GO:0001837epithelial to mesenchymal transition8.72e-021.00e+003.4581133
GO:0031625ubiquitin protein ligase binding8.80e-021.00e+002.011213180
GO:0001085RNA polymerase II transcription factor binding8.97e-021.00e+003.4151234
GO:0043407negative regulation of MAP kinase activity8.97e-021.00e+003.4151134
GO:0051701interaction with host8.97e-021.00e+003.4151434
GO:0005876spindle microtubule8.97e-021.00e+003.4151334
GO:0015629actin cytoskeleton9.05e-021.00e+001.98725183
GO:0006367transcription initiation from RNA polymerase II promoter9.14e-021.00e+001.97928184
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand9.22e-021.00e+003.3731235
GO:0032588trans-Golgi network membrane9.47e-021.00e+003.3331136
GO:0034332adherens junction organization9.47e-021.00e+003.3331136
GO:0032855positive regulation of Rac GTPase activity9.47e-021.00e+003.3331136
GO:0001895retina homeostasis9.47e-021.00e+003.3331136
GO:0001102RNA polymerase II activating transcription factor binding9.72e-021.00e+003.2931437
GO:0016301kinase activity9.72e-021.00e+003.2931337
GO:0051084'de novo' posttranslational protein folding9.72e-021.00e+003.2931437
GO:0018107peptidyl-threonine phosphorylation9.72e-021.00e+003.2931137
GO:00515394 iron, 4 sulfur cluster binding9.72e-021.00e+003.2931337
GO:0070527platelet aggregation9.97e-021.00e+003.2551238
GO:0090382phagosome maturation9.97e-021.00e+003.2551538
GO:0008026ATP-dependent helicase activity1.02e-011.00e+003.2171339
GO:0032092positive regulation of protein binding1.02e-011.00e+003.2171339
GO:0021766hippocampus development1.02e-011.00e+003.2171439
GO:0008033tRNA processing1.02e-011.00e+003.2171139
GO:0000737DNA catabolic process, endonucleolytic1.02e-011.00e+003.2171239
GO:0006383transcription from RNA polymerase III promoter1.02e-011.00e+003.2171339
GO:0031490chromatin DNA binding1.02e-011.00e+003.2171239
GO:0022627cytosolic small ribosomal subunit1.02e-011.00e+003.2171339
GO:0007595lactation1.02e-011.00e+003.2171239
GO:0007015actin filament organization1.05e-011.00e+003.1811240
GO:0008015blood circulation1.05e-011.00e+003.1811140
GO:0030145manganese ion binding1.07e-011.00e+003.1451141
GO:0043195terminal bouton1.07e-011.00e+003.1451141
GO:0031124mRNA 3'-end processing1.10e-011.00e+003.1101242
GO:0006418tRNA aminoacylation for protein translation1.10e-011.00e+003.1101542
GO:0005902microvillus1.10e-011.00e+003.1101242
GO:0014070response to organic cyclic compound1.12e-011.00e+003.0761343
GO:0001701in utero embryonic development1.14e-011.00e+001.78826210
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.15e-011.00e+003.0431344
GO:0006892post-Golgi vesicle-mediated transport1.15e-011.00e+003.0431244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.15e-011.00e+003.0431244
GO:0050434positive regulation of viral transcription1.15e-011.00e+003.0431544
GO:0043966histone H3 acetylation1.17e-011.00e+003.0111245
GO:0006369termination of RNA polymerase II transcription1.17e-011.00e+003.0111245
GO:0030136clathrin-coated vesicle1.19e-011.00e+002.9791146
GO:0045727positive regulation of translation1.19e-011.00e+002.9791446
GO:0021762substantia nigra development1.19e-011.00e+002.9791146
GO:0001047core promoter binding1.19e-011.00e+002.9791246
GO:0031100organ regeneration1.29e-011.00e+002.8591450
GO:0035690cellular response to drug1.29e-011.00e+002.8591250
GO:0045444fat cell differentiation1.32e-011.00e+002.8301151
GO:0045732positive regulation of protein catabolic process1.32e-011.00e+002.8301451
GO:0008168methyltransferase activity1.34e-011.00e+002.8021152
GO:0003725double-stranded RNA binding1.39e-011.00e+002.7481654
GO:0090305nucleic acid phosphodiester bond hydrolysis1.39e-011.00e+002.7481254
GO:0007623circadian rhythm1.39e-011.00e+002.7481154
GO:0002039p53 binding1.41e-011.00e+002.7211755
GO:0000226microtubule cytoskeleton organization1.41e-011.00e+002.7211355
GO:0007613memory1.43e-011.00e+002.6951256
GO:0006879cellular iron ion homeostasis1.46e-011.00e+002.6701557
GO:0000724double-strand break repair via homologous recombination1.46e-011.00e+002.6701657
GO:0012505endomembrane system1.46e-011.00e+002.6701257
GO:0030097hemopoiesis1.48e-011.00e+002.6451358
GO:0002244hematopoietic progenitor cell differentiation1.48e-011.00e+002.6451158
GO:0008217regulation of blood pressure1.48e-011.00e+002.6451558
GO:0045216cell-cell junction organization1.51e-011.00e+002.6201259
GO:0005643nuclear pore1.51e-011.00e+002.6201459
GO:0005840ribosome1.51e-011.00e+002.6201259
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.51e-011.00e+002.6201459
GO:0042802identical protein binding1.53e-011.00e+001.148318491
GO:0008013beta-catenin binding1.53e-011.00e+002.5961460
GO:0032481positive regulation of type I interferon production1.55e-011.00e+002.5721661
GO:0043025neuronal cell body1.55e-011.00e+001.51424254
GO:0005739mitochondrion1.59e-011.00e+000.7945241046
GO:0000776kinetochore1.60e-011.00e+002.5251463
GO:0042995cell projection1.60e-011.00e+002.5251663
GO:0001558regulation of cell growth1.67e-011.00e+002.4581466
GO:0071260cellular response to mechanical stimulus1.67e-011.00e+002.4581466
GO:0006368transcription elongation from RNA polymerase II promoter1.69e-011.00e+002.4361667
GO:0000777condensed chromosome kinetochore1.71e-011.00e+002.4151268
GO:0006338chromatin remodeling1.71e-011.00e+002.4151468
GO:0018105peptidyl-serine phosphorylation1.74e-011.00e+002.3941169
GO:0007283spermatogenesis1.76e-011.00e+001.39426276
GO:0034329cell junction assembly1.78e-011.00e+002.3531171
GO:0000785chromatin1.83e-011.00e+002.3131573
GO:0006767water-soluble vitamin metabolic process1.87e-011.00e+002.2741375
GO:0060070canonical Wnt signaling pathway1.87e-011.00e+002.2741375
GO:0046474glycerophospholipid biosynthetic process1.90e-011.00e+002.2551376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.92e-011.00e+002.2361577
GO:0008584male gonad development1.92e-011.00e+002.2361277
GO:0006766vitamin metabolic process1.94e-011.00e+002.2171378
GO:0006334nucleosome assembly1.96e-011.00e+002.1991479
GO:0007565female pregnancy1.99e-011.00e+002.1811280
GO:0019083viral transcription2.01e-011.00e+002.1631881
GO:0001889liver development2.03e-011.00e+002.1451382
GO:0001726ruffle2.03e-011.00e+002.1451482
GO:0043197dendritic spine2.05e-011.00e+002.1281283
GO:0006898receptor-mediated endocytosis2.12e-011.00e+002.0761286
GO:0006415translational termination2.14e-011.00e+002.0601887
GO:0009887organ morphogenesis2.18e-011.00e+002.0271289
GO:0000922spindle pole2.23e-011.00e+001.9951491
GO:0003690double-stranded DNA binding2.23e-011.00e+001.9951491
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.25e-011.00e+001.9791492
GO:0006928cellular component movement2.25e-011.00e+001.9791792
GO:0016605PML body2.25e-011.00e+001.9791592
GO:0007411axon guidance2.28e-011.00e+001.14929327
GO:0016310phosphorylation2.31e-011.00e+001.9331295
GO:0051082unfolded protein binding2.31e-011.00e+001.9331695
GO:0008283cell proliferation2.32e-011.00e+001.132212331
GO:0003682chromatin binding2.35e-011.00e+001.119212334
GO:0030426growth cone2.36e-011.00e+001.9031397
GO:0005178integrin binding2.36e-011.00e+001.9031297
GO:0071456cellular response to hypoxia2.38e-011.00e+001.8881498
GO:0045087innate immune response2.41e-011.00e+000.821320616
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.50e-011.00e+001.80218104
GO:0014069postsynaptic density2.54e-011.00e+001.77511106
GO:0005815microtubule organizing center2.63e-011.00e+001.72114110
GO:0020037heme binding2.65e-011.00e+001.70812111
GO:0005794Golgi apparatus2.66e-011.00e+000.743314650
GO:0015630microtubule cytoskeleton2.67e-011.00e+001.69515112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.71e-011.00e+001.670110114
GO:0005925focal adhesion2.72e-011.00e+000.971218370
GO:0048015phosphatidylinositol-mediated signaling2.73e-011.00e+001.65713115
GO:0019058viral life cycle2.73e-011.00e+001.657110115
GO:0072562blood microparticle2.75e-011.00e+001.64514116
GO:0005635nuclear envelope2.75e-011.00e+001.64516116
GO:0008284positive regulation of cell proliferation2.94e-011.00e+000.88828392
GO:0006511ubiquitin-dependent protein catabolic process2.97e-011.00e+001.51415127
GO:0046982protein heterodimerization activity3.01e-011.00e+000.862211399
GO:0016477cell migration3.05e-011.00e+001.46916131
GO:0009615response to virus3.06e-011.00e+001.45816132
GO:0031982vesicle3.10e-011.00e+001.436110134
GO:0006644phospholipid metabolic process3.16e-011.00e+001.40515137
GO:0000086G2/M transition of mitotic cell cycle3.16e-011.00e+001.40517137
GO:0007507heart development3.24e-011.00e+001.36315141
GO:0003735structural constituent of ribosome3.24e-011.00e+001.36318141
GO:0006366transcription from RNA polymerase II promoter3.28e-011.00e+000.771212425
GO:0008286insulin receptor signaling pathway3.29e-011.00e+001.33316144
GO:0010628positive regulation of gene expression3.39e-011.00e+001.28314149
GO:0046777protein autophosphorylation3.55e-011.00e+001.19913158
GO:0005198structural molecule activity3.57e-011.00e+001.19014159
GO:0008543fibroblast growth factor receptor signaling pathway3.57e-011.00e+001.19014159
GO:0045121membrane raft3.60e-011.00e+001.17218161
GO:0007596blood coagulation3.67e-011.00e+000.645214464
GO:0006397mRNA processing3.74e-011.00e+001.10213169
GO:0038095Fc-epsilon receptor signaling pathway3.78e-011.00e+001.08517171
GO:0030424axon3.80e-011.00e+001.07613172
GO:0006886intracellular protein transport3.81e-011.00e+001.06814173
GO:0000287magnesium ion binding3.83e-011.00e+001.06015174
GO:0055114oxidation-reduction process3.84e-011.00e+000.593211481
GO:0016607nuclear speck3.85e-011.00e+001.05114175
GO:0031965nuclear membrane3.86e-011.00e+001.04314176
GO:0045893positive regulation of transcription, DNA-templated3.90e-011.00e+000.575217487
GO:0004672protein kinase activity3.90e-011.00e+001.02712178
GO:0005667transcription factor complex3.90e-011.00e+001.02716178
GO:0003714transcription corepressor activity3.92e-011.00e+001.01917179
GO:0032403protein complex binding4.02e-011.00e+000.97117185
GO:0007173epidermal growth factor receptor signaling pathway4.12e-011.00e+000.92514191
GO:0004872receptor activity4.25e-011.00e+000.86613199
GO:0048471perinuclear region of cytoplasm4.25e-011.00e+000.472212523
GO:0005765lysosomal membrane4.54e-011.00e+000.73415218
GO:0005622intracellular4.67e-011.00e+000.68215226
GO:0003713transcription coactivator activity4.86e-011.00e+000.602110239
GO:0004842ubiquitin-protein transferase activity5.10e-011.00e+000.50314256
GO:0048011neurotrophin TRK receptor signaling pathway5.32e-011.00e+000.41016273
GO:0005975carbohydrate metabolic process5.34e-011.00e+000.40515274
GO:0006357regulation of transcription from RNA polymerase II promoter5.35e-011.00e+000.39916275
GO:0019899enzyme binding5.52e-011.00e+000.333111288
GO:0042493response to drug5.52e-011.00e+000.333111288
GO:0016567protein ubiquitination5.65e-011.00e+000.27915299
GO:0005743mitochondrial inner membrane5.67e-011.00e+000.27415300
GO:0008152metabolic process5.69e-011.00e+000.26415302
GO:0005856cytoskeleton5.80e-011.00e+000.22218311
GO:0004674protein serine/threonine kinase activity5.81e-011.00e+000.21716312
GO:0046872metal ion binding5.84e-011.00e+00-0.0144241465
GO:0035556intracellular signal transduction5.87e-011.00e+000.19416317
GO:0043565sequence-specific DNA binding6.39e-011.00e+00-0.00914365
GO:0006351transcription, DNA-templated6.48e-011.00e+00-0.1284251585
GO:0007155cell adhesion6.58e-011.00e+00-0.08218384
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.62e-011.00e+00-0.161219811
GO:0045892negative regulation of transcription, DNA-templated6.95e-011.00e+00-0.225114424
GO:0006468protein phosphorylation7.30e-011.00e+00-0.365110467
GO:0003677DNA binding7.32e-011.00e+00-0.3123261351
GO:0055085transmembrane transport7.64e-011.00e+00-0.50318514
GO:0008270zinc ion binding8.02e-011.00e+00-0.5572121067
GO:0000122negative regulation of transcription from RNA polymerase II promoter8.09e-011.00e+00-0.700112589
GO:0042803protein homodimerization activity8.24e-011.00e+00-0.767111617
GO:0003700sequence-specific DNA binding transcription factor activity8.79e-011.00e+00-1.044111748
GO:0007165signal transduction9.33e-011.00e+00-1.389117950
GO:0005615extracellular space9.44e-011.00e+00-1.4781171010
GO:0006355regulation of transcription, DNA-templated9.57e-011.00e+00-1.6061171104
GO:0005886plasma membrane9.65e-011.00e+00-0.9664382834
GO:0016021integral component of membrane9.99e-011.00e+00-2.7751152483