reg-snw-5887

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.858 2.95e-07 1.57e-03 3.19e-03
wolf-screen-ratio-mammosphere-adherent-reg-snw-5887 subnetwork

Genes (5)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
TUBG1 7283 390.9740.97336-Yes-
PSMD11 5717 151.0950.94035TFYes-
EIF2S2 8894 81.0750.94022-Yes-
PSMD3 5709 90.9860.93855TFYes-
[ RAD23B ] 5887 10.1580.85811-Yes-

Interactions (4)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD3 5709 RAD23B 5887 pd > reg.ITFP.txt: no annot
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot

Related GO terms (73)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000502proteasome complex1.04e-061.01e-026.96231747
GO:0005838proteasome regulatory particle9.42e-069.20e-028.6102410
GO:0022624proteasome accessory complex1.90e-051.86e-018.1242714
GO:0006521regulation of cellular amino acid metabolic process1.71e-041.00e+006.57421641
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.75e-041.00e+006.23121752
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.86e-041.00e+006.20421753
GO:0000278mitotic cell cycle3.14e-041.00e+004.222335314
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.19e-041.00e+006.12421756
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent3.31e-041.00e+006.09921657
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.67e-041.00e+006.02521760
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.79e-041.00e+006.00121661
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process4.31e-041.00e+005.90921765
GO:0002474antigen processing and presentation of peptide antigen via MHC class I5.00e-041.00e+005.80221670
GO:0000715nucleotide-excision repair, DNA damage recognition5.12e-041.00e+0010.931111
GO:0071942XPC complex5.12e-041.00e+0010.931111
GO:0000209protein polyubiquitination8.62e-041.00e+005.40821692
GO:0002176male germ cell proliferation1.02e-031.00e+009.931112
GO:0034641cellular nitrogen compound metabolic process1.12e-031.00e+005.217218105
GO:0042981regulation of apoptotic process1.27e-031.00e+005.124218112
GO:0010467gene expression1.51e-031.00e+003.453331535
GO:0005850eukaryotic translation initiation factor 2 complex1.54e-031.00e+009.347113
GO:0000082G1/S transition of mitotic cell cycle1.59e-031.00e+004.966224125
GO:0000212meiotic spindle organization2.05e-031.00e+008.931114
GO:0043248proteasome assembly2.05e-031.00e+008.931114
GO:0005827polar microtubule2.56e-031.00e+008.610115
GO:0000930gamma-tubulin complex2.56e-031.00e+008.610115
GO:0016071mRNA metabolic process2.91e-031.00e+004.522221170
GO:0032434regulation of proteasomal ubiquitin-dependent protein catabolic process3.07e-031.00e+008.347116
GO:0016070RNA metabolic process3.55e-031.00e+004.377221188
GO:0031122cytoplasmic microtubule organization4.09e-031.00e+007.931128
GO:0005829cytosol4.78e-031.00e+002.1284581787
GO:0030234enzyme regulator activity5.62e-031.00e+007.4721211
GO:0007020microtubule nucleation5.62e-031.00e+007.4721111
GO:0048863stem cell differentiation6.13e-031.00e+007.3471112
GO:0005654nucleoplasm6.27e-031.00e+002.742355876
GO:0042176regulation of protein catabolic process7.15e-031.00e+007.1241214
GO:0031593polyubiquitin binding7.66e-031.00e+007.0251115
GO:0008135translation factor activity, nucleic acid binding7.66e-031.00e+007.0251115
GO:0000718nucleotide-excision repair, DNA damage removal8.68e-031.00e+006.8441517
GO:0000794condensed nuclear chromosome9.18e-031.00e+006.7621318
GO:0043066negative regulation of apoptotic process1.01e-021.00e+003.601220322
GO:0006915apoptotic process1.62e-021.00e+003.248221411
GO:0016032viral process1.75e-021.00e+003.190232428
GO:0000226microtubule cytoskeleton organization1.83e-021.00e+005.7621236
GO:0003743translation initiation factor activity1.88e-021.00e+005.7221237
GO:0003684damaged DNA binding2.08e-021.00e+005.5741941
GO:0006289nucleotide-excision repair2.69e-021.00e+005.2041953
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.84e-021.00e+005.1241356
GO:0008584male gonad development2.89e-021.00e+005.0991257
GO:0003697single-stranded DNA binding2.89e-021.00e+005.0991657
GO:0005200structural constituent of cytoskeleton3.43e-021.00e+004.8441268
GO:0006511ubiquitin-dependent protein catabolic process4.62e-021.00e+004.4081292
GO:0000086G2/M transition of mitotic cell cycle4.87e-021.00e+004.3321597
GO:0006413translational initiation4.97e-021.00e+004.3021499
GO:0003924GTPase activity5.95e-021.00e+004.03713119
GO:0044281small molecule metabolic process6.26e-021.00e+002.210232844
GO:0006184GTP catabolic process6.48e-021.00e+003.90913130
GO:0001701in utero embryonic development7.64e-021.00e+003.66513154
GO:0007283spermatogenesis8.31e-021.00e+003.53912168
GO:0006412translation8.79e-021.00e+003.45613178
GO:0005525GTP binding9.69e-021.00e+003.30915197
GO:0006281DNA repair9.97e-021.00e+003.266119203
GO:0005515protein binding1.05e-011.00e+000.9224764124
GO:0005813centrosome1.06e-011.00e+003.17018217
GO:0016020membrane1.18e-011.00e+001.6942381207
GO:0005730nucleolus1.20e-011.00e+001.6822411217
GO:0003723RNA binding1.20e-011.00e+002.983111247
GO:0005737cytoplasm1.25e-011.00e+001.1543502633
GO:0044267cellular protein metabolic process1.68e-011.00e+002.47215352
GO:0070062extracellular vesicular exosome1.99e-011.00e+001.2512431641
GO:0005634nucleus2.08e-011.00e+000.8523673246
GO:0044822poly(A) RNA binding3.47e-011.00e+001.289125799
GO:0046872metal ion binding3.95e-011.00e+001.064110934