reg-snw-2982

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.807	2.02e-06	4.38e-03	7.98e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-2982 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
EIF2S2	8894	8	1.075	0.940	22	-	Yes	-
[ GUCY1A3 ]	2982	1	0.028	0.807	19	-	-	-
PSMC3	5702	3	0.719	0.830	21	-	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMC3	5702	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
GUCY1A3	2982	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot

Related GO terms (91)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	2.38e-06	2.32e-02	6.673	3	16	41
GO:0000502	proteasome complex	3.61e-06	3.52e-02	6.476	3	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.91e-06	4.80e-02	6.331	3	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.20e-06	5.08e-02	6.303	3	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.15e-06	6.01e-02	6.224	3	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.49e-06	6.34e-02	6.198	3	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.59e-06	7.41e-02	6.124	3	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.98e-06	7.79e-02	6.100	3	16	61
GO:0010467	gene expression	9.28e-06	9.07e-02	3.705	5	31	535
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	9.67e-06	9.44e-02	6.009	3	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.21e-05	1.18e-01	5.902	3	16	70
GO:0000209	protein polyubiquitination	2.76e-05	2.69e-01	5.507	3	16	92
GO:0000278	mitotic cell cycle	3.40e-05	3.32e-01	4.151	4	35	314
GO:0022624	proteasome accessory complex	3.99e-05	3.90e-01	7.639	2	7	14
GO:0034641	cellular nitrogen compound metabolic process	4.10e-05	4.00e-01	5.317	3	18	105
GO:0042981	regulation of apoptotic process	4.97e-05	4.86e-01	5.224	3	18	112
GO:0000082	G1/S transition of mitotic cell cycle	6.90e-05	6.74e-01	5.065	3	24	125
GO:0016071	mRNA metabolic process	1.72e-04	1.00e+00	4.622	3	21	170
GO:0016070	RNA metabolic process	2.32e-04	1.00e+00	4.476	3	21	188
GO:0005525	GTP binding	2.67e-04	1.00e+00	4.409	3	5	197
GO:0052565	response to defense-related host nitric oxide production	7.17e-04	1.00e+00	10.446	1	1	1
GO:0043066	negative regulation of apoptotic process	1.13e-03	1.00e+00	3.700	3	20	322
GO:0002176	male germ cell proliferation	1.43e-03	1.00e+00	9.446	1	1	2
GO:0008074	guanylate cyclase complex, soluble	1.43e-03	1.00e+00	9.446	1	1	2
GO:0005654	nucleoplasm	1.80e-03	1.00e+00	2.671	4	55	876
GO:0005850	eukaryotic translation initiation factor 2 complex	2.15e-03	1.00e+00	8.861	1	1	3
GO:0006915	apoptotic process	2.28e-03	1.00e+00	3.348	3	21	411
GO:0016032	viral process	2.56e-03	1.00e+00	3.290	3	32	428
GO:0000212	meiotic spindle organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0043248	proteasome assembly	2.86e-03	1.00e+00	8.446	1	1	4
GO:0030828	positive regulation of cGMP biosynthetic process	2.86e-03	1.00e+00	8.446	1	1	4
GO:0003924	GTPase activity	2.97e-03	1.00e+00	4.551	2	3	119
GO:0005829	cytosol	3.09e-03	1.00e+00	1.965	5	58	1787
GO:0006184	GTP catabolic process	3.54e-03	1.00e+00	4.424	2	3	130
GO:0060087	relaxation of vascular smooth muscle	3.58e-03	1.00e+00	8.124	1	1	5
GO:0005827	polar microtubule	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0004383	guanylate cyclase activity	4.29e-03	1.00e+00	7.861	1	1	6
GO:0031122	cytoplasmic microtubule organization	5.72e-03	1.00e+00	7.446	1	2	8
GO:0016020	membrane	5.97e-03	1.00e+00	2.209	4	38	1207
GO:0005838	proteasome regulatory particle	7.15e-03	1.00e+00	7.124	1	4	10
GO:0006182	cGMP biosynthetic process	7.15e-03	1.00e+00	7.124	1	1	10
GO:0007020	microtubule nucleation	7.86e-03	1.00e+00	6.987	1	1	11
GO:0007263	nitric oxide mediated signal transduction	8.57e-03	1.00e+00	6.861	1	1	12
GO:0048863	stem cell differentiation	8.57e-03	1.00e+00	6.861	1	1	12
GO:0010243	response to organonitrogen compound	1.00e-02	1.00e+00	6.639	1	1	14
GO:0008135	translation factor activity, nucleic acid binding	1.07e-02	1.00e+00	6.539	1	1	15
GO:1903506	regulation of nucleic acid-templated transcription	1.14e-02	1.00e+00	6.446	1	1	16
GO:0005839	proteasome core complex	1.14e-02	1.00e+00	6.446	1	9	16
GO:0004298	threonine-type endopeptidase activity	1.21e-02	1.00e+00	6.359	1	9	17
GO:0000794	condensed nuclear chromosome	1.28e-02	1.00e+00	6.276	1	3	18
GO:1903507	negative regulation of nucleic acid-templated transcription	1.50e-02	1.00e+00	6.054	1	1	21
GO:0044281	small molecule metabolic process	1.73e-02	1.00e+00	2.310	3	32	844
GO:0008015	blood circulation	2.20e-02	1.00e+00	5.492	1	1	31
GO:0015030	Cajal body	2.27e-02	1.00e+00	5.446	1	2	32
GO:0014070	response to organic cyclic compound	2.41e-02	1.00e+00	5.359	1	1	34
GO:0005515	protein binding	2.53e-02	1.00e+00	1.021	6	76	4124
GO:0000226	microtubule cytoskeleton organization	2.55e-02	1.00e+00	5.276	1	2	36
GO:0003743	translation initiation factor activity	2.62e-02	1.00e+00	5.237	1	2	37
GO:0008217	regulation of blood pressure	2.97e-02	1.00e+00	5.054	1	1	42
GO:0000932	cytoplasmic mRNA processing body	3.04e-02	1.00e+00	5.020	1	2	43
GO:0005681	spliceosomal complex	3.88e-02	1.00e+00	4.665	1	2	55
GO:0008584	male gonad development	4.02e-02	1.00e+00	4.613	1	2	57
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0005200	structural constituent of cytoskeleton	4.78e-02	1.00e+00	4.359	1	2	68
GO:0020037	heme binding	6.14e-02	1.00e+00	3.987	1	1	88
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	2	92
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	5	97
GO:0006413	translational initiation	6.89e-02	1.00e+00	3.817	1	4	99
GO:0016887	ATPase activity	6.95e-02	1.00e+00	3.802	1	6	100
GO:0006397	mRNA processing	7.63e-02	1.00e+00	3.665	1	2	110
GO:0004872	receptor activity	8.03e-02	1.00e+00	3.588	1	1	116
GO:0016607	nuclear speck	8.43e-02	1.00e+00	3.515	1	3	122
GO:0000398	mRNA splicing, via spliceosome	8.83e-02	1.00e+00	3.446	1	8	128
GO:0003714	transcription corepressor activity	9.42e-02	1.00e+00	3.348	1	2	137
GO:0001701	in utero embryonic development	1.05e-01	1.00e+00	3.179	1	3	154
GO:0044822	poly(A) RNA binding	1.07e-01	1.00e+00	1.804	2	25	799
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	7	165
GO:0006412	translation	1.21e-01	1.00e+00	2.970	1	3	178
GO:0003713	transcription coactivator activity	1.25e-01	1.00e+00	2.922	1	5	184
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	8	217
GO:0006200	ATP catabolic process	1.47e-01	1.00e+00	2.671	1	8	219
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0005634	nucleus	1.72e-01	1.00e+00	0.782	4	67	3246
GO:0005730	nucleolus	2.14e-01	1.00e+00	1.197	2	41	1217
GO:0007596	blood coagulation	2.19e-01	1.00e+00	2.041	1	4	339
GO:0044267	cellular protein metabolic process	2.27e-01	1.00e+00	1.987	1	5	352
GO:0070062	extracellular vesicular exosome	3.34e-01	1.00e+00	0.766	2	43	1641
GO:0005524	ATP binding	4.89e-01	1.00e+00	0.645	1	23	892
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0005737	cytoplasm	6.03e-01	1.00e+00	0.084	2	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-2982

Statistics

Genes (7)

Interactions (6)

Related GO terms (91)