reg-snw-1478

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.940	8.80e-09	2.25e-04	5.65e-04

wolf-screen-ratio-mammosphere-adherent-reg-snw-1478 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ CSTF2 ]	1478	1	-0.050	0.940	98	TF	-	Yes
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
EIF2S2	8894	8	1.075	0.940	22	-	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CSTF2	1478	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot

Related GO terms (122)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010467	gene expression	9.28e-06	9.07e-02	3.705	5	31	535
GO:0000398	mRNA splicing, via spliceosome	7.41e-05	7.24e-01	5.031	3	8	128
GO:0005654	nucleoplasm	1.03e-04	1.00e+00	2.993	5	55	876
GO:0008380	RNA splicing	1.58e-04	1.00e+00	4.665	3	7	165
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	5.10e-04	1.00e+00	5.831	2	3	49
GO:0003723	RNA binding	5.19e-04	1.00e+00	4.083	3	11	247
GO:0005681	spliceosomal complex	6.42e-04	1.00e+00	5.665	2	2	55
GO:0071013	catalytic step 2 spliceosome	7.90e-04	1.00e+00	5.515	2	5	61
GO:0044822	poly(A) RNA binding	1.27e-03	1.00e+00	2.804	4	25	799
GO:0002176	male germ cell proliferation	1.43e-03	1.00e+00	9.446	1	1	2
GO:0071920	cleavage body	1.43e-03	1.00e+00	9.446	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	2.15e-03	1.00e+00	8.861	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	2.15e-03	1.00e+00	8.861	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.15e-03	1.00e+00	8.861	1	1	3
GO:0005515	protein binding	2.39e-03	1.00e+00	1.244	7	76	4124
GO:0000212	meiotic spindle organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0071169	establishment of protein localization to chromatin	2.86e-03	1.00e+00	8.446	1	1	4
GO:0043248	proteasome assembly	2.86e-03	1.00e+00	8.446	1	1	4
GO:0003924	GTPase activity	2.97e-03	1.00e+00	4.551	2	3	119
GO:0006184	GTP catabolic process	3.54e-03	1.00e+00	4.424	2	3	130
GO:0005827	polar microtubule	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000812	Swr1 complex	5.01e-03	1.00e+00	7.639	1	2	7
GO:0031011	Ino80 complex	5.72e-03	1.00e+00	7.446	1	2	8
GO:0031122	cytoplasmic microtubule organization	5.72e-03	1.00e+00	7.446	1	2	8
GO:0016020	membrane	5.97e-03	1.00e+00	2.209	4	38	1207
GO:0005730	nucleolus	6.15e-03	1.00e+00	2.197	4	41	1217
GO:0000166	nucleotide binding	6.39e-03	1.00e+00	3.987	2	6	176
GO:0006379	mRNA cleavage	6.44e-03	1.00e+00	7.276	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	6.44e-03	1.00e+00	7.276	1	1	9
GO:0008266	poly(U) RNA binding	6.44e-03	1.00e+00	7.276	1	1	9
GO:0043968	histone H2A acetylation	7.15e-03	1.00e+00	7.124	1	2	10
GO:0005838	proteasome regulatory particle	7.15e-03	1.00e+00	7.124	1	4	10
GO:0007020	microtubule nucleation	7.86e-03	1.00e+00	6.987	1	1	11
GO:0045120	pronucleus	7.86e-03	1.00e+00	6.987	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	7.86e-03	1.00e+00	6.987	1	2	11
GO:0005525	GTP binding	7.95e-03	1.00e+00	3.824	2	5	197
GO:0035267	NuA4 histone acetyltransferase complex	8.57e-03	1.00e+00	6.861	1	3	12
GO:0048863	stem cell differentiation	8.57e-03	1.00e+00	6.861	1	1	12
GO:0035066	positive regulation of histone acetylation	9.28e-03	1.00e+00	6.746	1	1	13
GO:0071392	cellular response to estradiol stimulus	9.28e-03	1.00e+00	6.746	1	1	13
GO:0022624	proteasome accessory complex	1.00e-02	1.00e+00	6.639	1	7	14
GO:0008135	translation factor activity, nucleic acid binding	1.07e-02	1.00e+00	6.539	1	1	15
GO:0005719	nuclear euchromatin	1.14e-02	1.00e+00	6.446	1	1	16
GO:0071339	MLL1 complex	1.28e-02	1.00e+00	6.276	1	2	18
GO:0006378	mRNA polyadenylation	1.28e-02	1.00e+00	6.276	1	1	18
GO:0003678	DNA helicase activity	1.28e-02	1.00e+00	6.276	1	3	18
GO:0000794	condensed nuclear chromosome	1.28e-02	1.00e+00	6.276	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.124	1	2	20
GO:0043967	histone H4 acetylation	1.57e-02	1.00e+00	5.987	1	2	22
GO:0004003	ATP-dependent DNA helicase activity	1.78e-02	1.00e+00	5.802	1	2	25
GO:0031492	nucleosomal DNA binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.78e-02	1.00e+00	5.802	1	2	25
GO:0000278	mitotic cell cycle	1.94e-02	1.00e+00	3.151	2	35	314
GO:0034644	cellular response to UV	1.99e-02	1.00e+00	5.639	1	2	28
GO:0031490	chromatin DNA binding	2.20e-02	1.00e+00	5.492	1	1	31
GO:0015030	Cajal body	2.27e-02	1.00e+00	5.446	1	2	32
GO:0042802	identical protein binding	2.44e-02	1.00e+00	2.978	2	7	354
GO:0005829	cytosol	2.45e-02	1.00e+00	1.643	4	58	1787
GO:0031124	mRNA 3'-end processing	2.48e-02	1.00e+00	5.317	1	2	35
GO:0000226	microtubule cytoskeleton organization	2.55e-02	1.00e+00	5.276	1	2	36
GO:0003743	translation initiation factor activity	2.62e-02	1.00e+00	5.237	1	2	37
GO:0040008	regulation of growth	2.62e-02	1.00e+00	5.237	1	2	37
GO:0006369	termination of RNA polymerase II transcription	2.69e-02	1.00e+00	5.198	1	2	38
GO:0032508	DNA duplex unwinding	2.69e-02	1.00e+00	5.198	1	5	38
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2.83e-02	1.00e+00	5.124	1	2	40
GO:0006521	regulation of cellular amino acid metabolic process	2.90e-02	1.00e+00	5.088	1	16	41
GO:0003684	damaged DNA binding	2.90e-02	1.00e+00	5.088	1	9	41
GO:0000502	proteasome complex	3.32e-02	1.00e+00	4.891	1	17	47
GO:0006310	DNA recombination	3.53e-02	1.00e+00	4.802	1	6	50
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.67e-02	1.00e+00	4.746	1	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.74e-02	1.00e+00	4.718	1	17	53
GO:0006338	chromatin remodeling	3.88e-02	1.00e+00	4.665	1	2	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.95e-02	1.00e+00	4.639	1	17	56
GO:0008584	male gonad development	4.02e-02	1.00e+00	4.613	1	2	57
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.02e-02	1.00e+00	4.613	1	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.22e-02	1.00e+00	4.539	1	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.29e-02	1.00e+00	4.515	1	16	61
GO:0005634	nucleus	4.47e-02	1.00e+00	1.104	5	67	3246
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.57e-02	1.00e+00	4.424	1	17	65
GO:0005200	structural constituent of cytoskeleton	4.78e-02	1.00e+00	4.359	1	2	68
GO:0006325	chromatin organization	4.91e-02	1.00e+00	4.317	1	3	70
GO:0051082	unfolded protein binding	4.91e-02	1.00e+00	4.317	1	4	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.91e-02	1.00e+00	4.317	1	16	70
GO:0016363	nuclear matrix	5.12e-02	1.00e+00	4.256	1	7	73
GO:0001649	osteoblast differentiation	5.19e-02	1.00e+00	4.237	1	2	74
GO:0030529	ribonucleoprotein complex	5.73e-02	1.00e+00	4.088	1	4	82
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	2	92
GO:0000209	protein polyubiquitination	6.41e-02	1.00e+00	3.922	1	16	92
GO:0006457	protein folding	6.75e-02	1.00e+00	3.846	1	4	97
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	5	97
GO:0006413	translational initiation	6.89e-02	1.00e+00	3.817	1	4	99
GO:0016887	ATPase activity	6.95e-02	1.00e+00	3.802	1	6	100
GO:0034641	cellular nitrogen compound metabolic process	7.29e-02	1.00e+00	3.732	1	18	105
GO:0000790	nuclear chromatin	7.56e-02	1.00e+00	3.678	1	3	109
GO:0006397	mRNA processing	7.63e-02	1.00e+00	3.665	1	2	110
GO:0042981	regulation of apoptotic process	7.76e-02	1.00e+00	3.639	1	18	112
GO:0016607	nuclear speck	8.43e-02	1.00e+00	3.515	1	3	122
GO:0000082	G1/S transition of mitotic cell cycle	8.63e-02	1.00e+00	3.480	1	24	125
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.75e-02	1.00e+00	3.296	1	2	142
GO:0070062	extracellular vesicular exosome	9.77e-02	1.00e+00	1.351	3	43	1641
GO:0005622	intracellular	9.95e-02	1.00e+00	3.266	1	1	145
GO:0001701	in utero embryonic development	1.05e-01	1.00e+00	3.179	1	3	154
GO:0016071	mRNA metabolic process	1.16e-01	1.00e+00	3.037	1	21	170
GO:0006412	translation	1.21e-01	1.00e+00	2.970	1	3	178
GO:0016070	RNA metabolic process	1.27e-01	1.00e+00	2.891	1	21	188
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	19	203
GO:0043234	protein complex	1.41e-01	1.00e+00	2.732	1	8	210
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	8	217
GO:0006200	ATP catabolic process	1.47e-01	1.00e+00	2.671	1	8	219
GO:0043066	negative regulation of apoptotic process	2.09e-01	1.00e+00	2.115	1	20	322
GO:0006366	transcription from RNA polymerase II promoter	2.20e-01	1.00e+00	2.032	1	6	341
GO:0044267	cellular protein metabolic process	2.27e-01	1.00e+00	1.987	1	5	352
GO:0006915	apoptotic process	2.60e-01	1.00e+00	1.763	1	21	411
GO:0016032	viral process	2.69e-01	1.00e+00	1.705	1	32	428
GO:0005737	cytoplasm	2.85e-01	1.00e+00	0.669	3	50	2633
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.115	1	8	644
GO:0044281	small molecule metabolic process	4.69e-01	1.00e+00	0.725	1	32	844
GO:0005524	ATP binding	4.89e-01	1.00e+00	0.645	1	23	892
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0006351	transcription, DNA-templated	5.58e-01	1.00e+00	0.375	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-1478

Statistics

Genes (7)

Interactions (7)

Related GO terms (122)