reg-snw-2237

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.894	6.72e-08	6.99e-04	1.55e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-2237 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
EIF2S2	8894	8	1.075	0.940	22	-	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
POLA1	5422	2	0.593	0.894	45	TF	Yes	-
[ FEN1 ]	2237	1	0.014	0.894	89	-	-	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
FEN1	2237	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
FEN1	2237	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
FEN1	2237	POLA1	5422	pd	<	reg.ITFP.txt: no annot

Related GO terms (156)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.40e-06	1.37e-02	3.116	7	55	876
GO:0000278	mitotic cell cycle	3.77e-06	3.69e-02	4.111	5	35	314
GO:0010467	gene expression	5.08e-05	4.96e-01	3.342	5	31	535
GO:0032201	telomere maintenance via semi-conservative replication	1.42e-04	1.00e+00	6.762	2	7	20
GO:0000082	G1/S transition of mitotic cell cycle	1.63e-04	1.00e+00	4.703	3	24	125
GO:0000722	telomere maintenance via recombination	1.73e-04	1.00e+00	6.624	2	7	22
GO:0016020	membrane	2.12e-04	1.00e+00	2.431	6	38	1207
GO:0005730	nucleolus	2.22e-04	1.00e+00	2.419	6	41	1217
GO:0006271	DNA strand elongation involved in DNA replication	3.03e-04	1.00e+00	6.225	2	8	29
GO:0005515	protein binding	4.25e-04	1.00e+00	1.244	9	76	4124
GO:0006521	regulation of cellular amino acid metabolic process	6.08e-04	1.00e+00	5.726	2	16	41
GO:0006281	DNA repair	6.78e-04	1.00e+00	4.003	3	19	203
GO:0000502	proteasome complex	7.99e-04	1.00e+00	5.529	2	17	47
GO:0000723	telomere maintenance	7.99e-04	1.00e+00	5.529	2	8	47
GO:0008309	double-stranded DNA exodeoxyribonuclease activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.78e-04	1.00e+00	5.383	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.02e-03	1.00e+00	5.356	2	17	53
GO:0005681	spliceosomal complex	1.09e-03	1.00e+00	5.302	2	2	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.13e-03	1.00e+00	5.276	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.17e-03	1.00e+00	5.251	2	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.30e-03	1.00e+00	5.177	2	17	60
GO:0071013	catalytic step 2 spliceosome	1.34e-03	1.00e+00	5.153	2	5	61
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.34e-03	1.00e+00	5.153	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.52e-03	1.00e+00	5.061	2	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.77e-03	1.00e+00	4.954	2	16	70
GO:0006272	leading strand elongation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0002176	male germ cell proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0016363	nuclear matrix	1.92e-03	1.00e+00	4.894	2	7	73
GO:0005850	eukaryotic translation initiation factor 2 complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006269	DNA replication, synthesis of RNA primer	2.76e-03	1.00e+00	8.499	1	2	3
GO:0005658	alpha DNA polymerase:primase complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0043137	DNA replication, removal of RNA primer	2.76e-03	1.00e+00	8.499	1	1	3
GO:0017108	5'-flap endonuclease activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0003896	DNA primase activity	2.76e-03	1.00e+00	8.499	1	2	3
GO:0000209	protein polyubiquitination	3.03e-03	1.00e+00	4.560	2	16	92
GO:0006260	DNA replication	3.16e-03	1.00e+00	4.529	2	11	94
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0043248	proteasome assembly	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006273	lagging strand elongation	3.68e-03	1.00e+00	8.083	1	2	4
GO:0034641	cellular nitrogen compound metabolic process	3.92e-03	1.00e+00	4.369	2	18	105
GO:0042981	regulation of apoptotic process	4.45e-03	1.00e+00	4.276	2	18	112
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0001882	nucleoside binding	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0004523	RNA-DNA hybrid ribonuclease activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0003924	GTPase activity	5.01e-03	1.00e+00	4.189	2	3	119
GO:0016032	viral process	5.76e-03	1.00e+00	2.927	3	32	428
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	8	128
GO:0006184	GTP catabolic process	5.96e-03	1.00e+00	4.061	2	3	130
GO:0000731	DNA synthesis involved in DNA repair	6.44e-03	1.00e+00	7.276	1	1	7
GO:0008409	5'-3' exonuclease activity	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000812	Swr1 complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0019985	translesion synthesis	7.35e-03	1.00e+00	7.083	1	1	8
GO:0009650	UV protection	7.35e-03	1.00e+00	7.083	1	1	8
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0031011	Ino80 complex	7.35e-03	1.00e+00	7.083	1	2	8
GO:0005634	nucleus	8.11e-03	1.00e+00	1.226	7	67	3246
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0043968	histone H2A acetylation	9.18e-03	1.00e+00	6.762	1	2	10
GO:0005838	proteasome regulatory particle	9.18e-03	1.00e+00	6.762	1	4	10
GO:0008380	RNA splicing	9.45e-03	1.00e+00	3.717	2	7	165
GO:0016071	mRNA metabolic process	1.00e-02	1.00e+00	3.674	2	21	170
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0008408	3'-5' exonuclease activity	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0000166	nucleotide binding	1.07e-02	1.00e+00	3.624	2	6	176
GO:0035267	NuA4 histone acetyltransferase complex	1.10e-02	1.00e+00	6.499	1	3	12
GO:0048863	stem cell differentiation	1.10e-02	1.00e+00	6.499	1	1	12
GO:0004527	exonuclease activity	1.10e-02	1.00e+00	6.499	1	1	12
GO:0000738	DNA catabolic process, exonucleolytic	1.19e-02	1.00e+00	6.383	1	3	13
GO:0004519	endonuclease activity	1.19e-02	1.00e+00	6.383	1	1	13
GO:0016070	RNA metabolic process	1.21e-02	1.00e+00	3.529	2	21	188
GO:0010243	response to organonitrogen compound	1.28e-02	1.00e+00	6.276	1	1	14
GO:0022624	proteasome accessory complex	1.28e-02	1.00e+00	6.276	1	7	14
GO:0005525	GTP binding	1.33e-02	1.00e+00	3.461	2	5	197
GO:0005829	cytosol	1.34e-02	1.00e+00	1.602	5	58	1787
GO:0008135	translation factor activity, nucleic acid binding	1.37e-02	1.00e+00	6.177	1	1	15
GO:0003887	DNA-directed DNA polymerase activity	1.47e-02	1.00e+00	6.083	1	2	16
GO:0005839	proteasome core complex	1.47e-02	1.00e+00	6.083	1	9	16
GO:0006270	DNA replication initiation	1.56e-02	1.00e+00	5.996	1	4	17
GO:0004298	threonine-type endopeptidase activity	1.56e-02	1.00e+00	5.996	1	9	17
GO:0006297	nucleotide-excision repair, DNA gap filling	1.65e-02	1.00e+00	5.914	1	5	18
GO:0003678	DNA helicase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0071339	MLL1 complex	1.65e-02	1.00e+00	5.914	1	2	18
GO:0006303	double-strand break repair via nonhomologous end joining	1.65e-02	1.00e+00	5.914	1	4	18
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1.92e-02	1.00e+00	5.691	1	2	21
GO:0051539	4 iron, 4 sulfur cluster binding	1.92e-02	1.00e+00	5.691	1	1	21
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.92e-02	1.00e+00	5.691	1	1	21
GO:0043967	histone H4 acetylation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0003723	RNA binding	2.04e-02	1.00e+00	3.135	2	11	247
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0030145	manganese ion binding	2.37e-02	1.00e+00	5.383	1	1	26
GO:0000737	DNA catabolic process, endonucleolytic	2.64e-02	1.00e+00	5.225	1	3	29
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.82e-02	1.00e+00	5.129	1	2	31
GO:0015030	Cajal body	2.91e-02	1.00e+00	5.083	1	2	32
GO:0006284	base-excision repair	2.91e-02	1.00e+00	5.083	1	8	32
GO:0014070	response to organic cyclic compound	3.09e-02	1.00e+00	4.996	1	1	34
GO:0044822	poly(A) RNA binding	3.15e-02	1.00e+00	2.026	3	25	799
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0043066	negative regulation of apoptotic process	3.35e-02	1.00e+00	2.753	2	20	322
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	2	37
GO:0040008	regulation of growth	3.36e-02	1.00e+00	4.874	1	2	37
GO:0032508	DNA duplex unwinding	3.45e-02	1.00e+00	4.836	1	5	38
GO:0007613	memory	3.72e-02	1.00e+00	4.726	1	1	41
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	9	41
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.43e-02	1.00e+00	4.469	1	3	49
GO:0006310	DNA recombination	4.52e-02	1.00e+00	4.440	1	6	50
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0006302	double-strand break repair	4.69e-02	1.00e+00	4.383	1	8	52
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	43	1641
GO:0008584	male gonad development	5.13e-02	1.00e+00	4.251	1	2	57
GO:0006915	apoptotic process	5.23e-02	1.00e+00	2.400	2	21	411
GO:0000785	chromatin	5.31e-02	1.00e+00	4.201	1	5	59
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0006325	chromatin organization	6.27e-02	1.00e+00	3.954	1	3	70
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	4	82
GO:0003690	double-stranded DNA binding	7.40e-02	1.00e+00	3.708	1	3	83
GO:0005635	nuclear envelope	7.40e-02	1.00e+00	3.708	1	4	83
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	2	92
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0006413	translational initiation	8.77e-02	1.00e+00	3.454	1	4	99
GO:0016887	ATPase activity	8.85e-02	1.00e+00	3.440	1	6	100
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	2	110
GO:0000287	magnesium ion binding	1.01e-01	1.00e+00	3.238	1	2	115
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	3	122
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0001701	in utero embryonic development	1.33e-01	1.00e+00	2.817	1	3	154
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	8	165
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0006412	translation	1.53e-01	1.00e+00	2.608	1	3	178
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0043234	protein complex	1.78e-01	1.00e+00	2.369	1	8	210
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	32	844
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0019901	protein kinase binding	1.95e-01	1.00e+00	2.225	1	11	232
GO:0008283	cell proliferation	2.00e-01	1.00e+00	2.183	1	6	239
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	50	2633
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	6	252
GO:0046872	metal ion binding	2.10e-01	1.00e+00	1.216	2	10	934
GO:0003677	DNA binding	2.15e-01	1.00e+00	1.196	2	18	947
GO:0046982	protein heterodimerization activity	2.19e-01	1.00e+00	2.034	1	5	265
GO:0044267	cellular protein metabolic process	2.81e-01	1.00e+00	1.624	1	5	352
GO:0042802	identical protein binding	2.83e-01	1.00e+00	1.616	1	7	354
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	11	659
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	23	892
GO:0006351	transcription, DNA-templated	6.50e-01	1.00e+00	0.012	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-2237

Statistics

Genes (9)

Interactions (9)

Related GO terms (156)