Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.934 | 1.80e-15 | 2.53e-03 | 4.08e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
[ CHKB ] | 1120 | 1 | -0.169 | 0.934 | 42 | - | Yes |
ATP6V1B2 | 526 | 44 | 0.881 | 1.076 | 278 | - | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
CDC16 | 8881 | 25 | 0.950 | 1.020 | 80 | Yes | - |
EEF2 | 1938 | 27 | 0.890 | 1.043 | 301 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
EFTUD2 | 9343 | 7 | 0.883 | 0.969 | 78 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
GSK3B | 2932 | 2 | 0.475 | 0.934 | 319 | - | Yes |
TUBG1 | 7283 | 3 | 0.974 | 0.938 | 55 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
GSK3B | 2932 | EFTUD2 | 9343 | pp | -- | int.I2D: BioGrid, MINT; int.Mint: MI:0915(physical association) |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
EEF2 | 1938 | PGD | 5226 | pp | -- | int.I2D: BioGrid_Yeast |
ATP6V1B2 | 526 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | CDC16 | 8881 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ATP6V1B2 | 526 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | ATP6V1B2 | 526 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
CHKB | 1120 | GSK3B | 2932 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
GSK3B | 2932 | TUBG1 | 7283 | pp | -- | int.I2D: MINT |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
ATP6V1B2 | 526 | CHKB | 1120 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
CHKB | 1120 | PSMD3 | 5709 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ATP6V1B2 | 526 | CDC16 | 8881 | pp | -- | int.I2D: IntAct_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0005829 | cytosol | 4.85e-11 | 6.99e-07 | 2.438 | 15 | 132 | 2496 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.11e-11 | 7.37e-07 | 6.379 | 6 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.09e-11 | 1.17e-06 | 6.272 | 6 | 22 | 70 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.14e-10 | 1.65e-06 | 6.192 | 6 | 22 | 74 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.71e-10 | 2.46e-06 | 6.097 | 6 | 23 | 79 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.73e-09 | 2.50e-05 | 6.494 | 5 | 17 | 50 |
GO:0000502 | proteasome complex | 3.72e-09 | 5.37e-05 | 6.280 | 5 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 6.17e-09 | 8.90e-05 | 6.138 | 5 | 19 | 64 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.13e-08 | 1.63e-04 | 5.968 | 5 | 20 | 72 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.39e-08 | 2.00e-04 | 5.909 | 5 | 20 | 75 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 3.91e-08 | 5.64e-04 | 5.614 | 5 | 21 | 92 |
GO:0016071 | mRNA metabolic process | 8.99e-08 | 1.30e-03 | 4.600 | 6 | 31 | 223 |
GO:0000278 | mitotic cell cycle | 9.45e-08 | 1.36e-03 | 4.012 | 7 | 48 | 391 |
GO:0000209 | protein polyubiquitination | 1.26e-07 | 1.81e-03 | 5.280 | 5 | 20 | 116 |
GO:0016070 | RNA metabolic process | 1.65e-07 | 2.38e-03 | 4.453 | 6 | 32 | 247 |
GO:0010467 | gene expression | 1.90e-07 | 2.74e-03 | 3.430 | 8 | 59 | 669 |
GO:0000082 | G1/S transition of mitotic cell cycle | 4.38e-07 | 6.32e-03 | 4.919 | 5 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 4.53e-07 | 6.54e-03 | 4.909 | 5 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.68e-07 | 1.25e-02 | 4.720 | 5 | 20 | 171 |
GO:0005839 | proteasome core complex | 9.05e-07 | 1.30e-02 | 7.231 | 3 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.07e-06 | 1.55e-02 | 7.153 | 3 | 8 | 19 |
GO:0043066 | negative regulation of apoptotic process | 3.88e-06 | 5.60e-02 | 3.673 | 6 | 31 | 424 |
GO:0070062 | extracellular vesicular exosome | 5.10e-06 | 7.36e-02 | 2.047 | 11 | 104 | 2400 |
GO:0005654 | nucleoplasm | 7.30e-06 | 1.05e-01 | 2.737 | 8 | 76 | 1082 |
GO:0016032 | viral process | 1.46e-05 | 2.11e-01 | 3.340 | 6 | 55 | 534 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 3.22e-05 | 4.64e-01 | 7.816 | 2 | 4 | 8 |
GO:0005838 | proteasome regulatory particle | 7.57e-05 | 1.00e+00 | 7.231 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 1.55e-04 | 1.00e+00 | 6.729 | 2 | 8 | 17 |
GO:0044281 | small molecule metabolic process | 1.68e-04 | 1.00e+00 | 2.381 | 7 | 58 | 1211 |
GO:0030529 | ribonucleoprotein complex | 2.37e-04 | 1.00e+00 | 4.594 | 3 | 8 | 112 |
GO:0006915 | apoptotic process | 2.54e-04 | 1.00e+00 | 3.022 | 5 | 33 | 555 |
GO:0005844 | polysome | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 4 | 23 |
GO:0019901 | protein kinase binding | 3.38e-04 | 1.00e+00 | 3.508 | 4 | 21 | 317 |
GO:0005813 | centrosome | 3.76e-04 | 1.00e+00 | 3.467 | 4 | 14 | 326 |
GO:0033572 | transferrin transport | 4.93e-04 | 1.00e+00 | 5.909 | 2 | 5 | 30 |
GO:0019521 | D-gluconate metabolic process | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0003924 | GTPase activity | 1.23e-03 | 1.00e+00 | 3.779 | 3 | 12 | 197 |
GO:0016020 | membrane | 1.27e-03 | 1.00e+00 | 1.908 | 7 | 90 | 1681 |
GO:0006184 | GTP catabolic process | 1.56e-03 | 1.00e+00 | 3.660 | 3 | 12 | 214 |
GO:0044337 | canonical Wnt signaling pathway involved in positive regulation of apoptotic process | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0014043 | negative regulation of neuron maturation | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0004103 | choline kinase activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0071109 | superior temporal gyrus development | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:2000077 | negative regulation of type B pancreatic cell development | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 2 | 2 |
GO:0005055 | laminin receptor activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0000320 | re-entry into mitotic cell cycle | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:2000466 | negative regulation of glycogen (starch) synthase activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0044027 | hypermethylation of CpG island | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0071439 | clathrin complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0000212 | meiotic spindle organization | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0004305 | ethanolamine kinase activity | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0051534 | negative regulation of NFAT protein import into nucleus | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0042470 | melanosome | 4.46e-03 | 1.00e+00 | 4.308 | 2 | 9 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 4.46e-03 | 1.00e+00 | 4.308 | 2 | 8 | 91 |
GO:0005525 | GTP binding | 4.47e-03 | 1.00e+00 | 3.125 | 3 | 12 | 310 |
GO:0006414 | translational elongation | 4.65e-03 | 1.00e+00 | 4.277 | 2 | 13 | 93 |
GO:0043248 | proteasome assembly | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0036016 | cellular response to interleukin-3 | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:2000738 | positive regulation of stem cell differentiation | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0005827 | polar microtubule | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0030118 | clathrin coat | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 6 |
GO:0050774 | negative regulation of dendrite morphogenesis | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0010614 | negative regulation of cardiac muscle hypertrophy | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0005819 | spindle | 6.68e-03 | 1.00e+00 | 4.009 | 2 | 7 | 112 |
GO:0005515 | protein binding | 7.39e-03 | 1.00e+00 | 0.845 | 12 | 184 | 6024 |
GO:0000028 | ribosomal small subunit assembly | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0006657 | CDP-choline pathway | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0033180 | proton-transporting V-type ATPase, V1 domain | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0030132 | clathrin coat of coated pit | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0000930 | gamma-tubulin complex | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0070688 | MLL5-L complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0045719 | negative regulation of glycogen biosynthetic process | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0035372 | protein localization to microtubule | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0008494 | translation activator activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0048156 | tau protein binding | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 9 |
GO:0005634 | nucleus | 1.06e-02 | 1.00e+00 | 0.984 | 10 | 136 | 4559 |
GO:0006098 | pentose-phosphate shunt | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 4 | 10 |
GO:0010226 | response to lithium ion | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 2 | 10 |
GO:0061024 | membrane organization | 1.10e-02 | 1.00e+00 | 3.636 | 2 | 7 | 145 |
GO:0030877 | beta-catenin destruction complex | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 1 | 10 |
GO:0032886 | regulation of microtubule-based process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 12 |
GO:0034236 | protein kinase A catalytic subunit binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 12 |
GO:0006646 | phosphatidylethanolamine biosynthetic process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 12 |
GO:0050321 | tau-protein kinase activity | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 12 |
GO:0031334 | positive regulation of protein complex assembly | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 2 | 13 |
GO:0030234 | enzyme regulator activity | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0046827 | positive regulation of protein export from nucleus | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0044267 | cellular protein metabolic process | 1.44e-02 | 1.00e+00 | 2.512 | 3 | 29 | 474 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 4 | 14 |
GO:0031333 | negative regulation of protein complex assembly | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 14 |
GO:0048168 | regulation of neuronal synaptic plasticity | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 2 | 14 |
GO:0007020 | microtubule nucleation | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 14 |
GO:0006349 | regulation of gene expression by genetic imprinting | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 15 |
GO:0046034 | ATP metabolic process | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 15 |
GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 15 |
GO:0042176 | regulation of protein catabolic process | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 3 | 16 |
GO:0035255 | ionotropic glutamate receptor binding | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0007520 | myoblast fusion | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0003746 | translation elongation factor activity | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 17 |
GO:0031122 | cytoplasmic microtubule organization | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0007088 | regulation of mitosis | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0015078 | hydrogen ion transmembrane transporter activity | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 3 | 19 |
GO:0048863 | stem cell differentiation | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0005680 | anaphase-promoting complex | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 4 | 20 |
GO:0001954 | positive regulation of cell-matrix adhesion | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 21 |
GO:0030010 | establishment of cell polarity | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 21 |
GO:0006656 | phosphatidylcholine biosynthetic process | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 2 | 22 |
GO:0030863 | cortical cytoskeleton | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 4 | 22 |
GO:0043236 | laminin binding | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 4 | 23 |
GO:0007067 | mitotic nuclear division | 2.56e-02 | 1.00e+00 | 2.990 | 2 | 14 | 227 |
GO:0044822 | poly(A) RNA binding | 2.56e-02 | 1.00e+00 | 1.772 | 4 | 49 | 1056 |
GO:0006412 | translation | 2.62e-02 | 1.00e+00 | 2.971 | 2 | 20 | 230 |
GO:0000794 | condensed nuclear chromosome | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 2 | 24 |
GO:0005977 | glycogen metabolic process | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 1 | 24 |
GO:0006611 | protein export from nucleus | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 3 | 25 |
GO:0051059 | NF-kappaB binding | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 2 | 25 |
GO:0070979 | protein K11-linked ubiquitination | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 6 | 26 |
GO:0015991 | ATP hydrolysis coupled proton transport | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 4 | 26 |
GO:0050661 | NADP binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 2 | 27 |
GO:0043022 | ribosome binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 4 | 27 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 28 |
GO:0015992 | proton transport | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 3 | 29 |
GO:0043198 | dendritic shaft | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 1 | 29 |
GO:0031623 | receptor internalization | 3.39e-02 | 1.00e+00 | 4.862 | 1 | 2 | 31 |
GO:0007094 | mitotic spindle assembly checkpoint | 3.39e-02 | 1.00e+00 | 4.862 | 1 | 4 | 31 |
GO:0032091 | negative regulation of protein binding | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 1 | 32 |
GO:0043407 | negative regulation of MAP kinase activity | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 2 | 32 |
GO:0051701 | interaction with host | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 4 | 32 |
GO:0016301 | kinase activity | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 3 | 33 |
GO:0001837 | epithelial to mesenchymal transition | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 1 | 33 |
GO:0001085 | RNA polymerase II transcription factor binding | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 33 |
GO:0032588 | trans-Golgi network membrane | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 1 | 34 |
GO:0005876 | spindle microtubule | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 2 | 34 |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 3 | 35 |
GO:0032855 | positive regulation of Rac GTPase activity | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 1 | 35 |
GO:0034332 | adherens junction organization | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 36 |
GO:0090382 | phagosome maturation | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 5 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.03e-02 | 1.00e+00 | 4.607 | 1 | 4 | 37 |
GO:0021766 | hippocampus development | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 4 | 38 |
GO:0005902 | microvillus | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0043234 | protein complex | 4.14e-02 | 1.00e+00 | 2.612 | 2 | 18 | 295 |
GO:0032092 | positive regulation of protein binding | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 3 | 38 |
GO:0070527 | platelet aggregation | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 4 | 39 |
GO:0030136 | clathrin-coated vesicle | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 4 | 42 |
GO:0006892 | post-Golgi vesicle-mediated transport | 4.67e-02 | 1.00e+00 | 4.390 | 1 | 3 | 43 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0021762 | substantia nigra development | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 2 | 44 |
GO:0015030 | Cajal body | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0045727 | positive regulation of translation | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0007411 | axon guidance | 4.77e-02 | 1.00e+00 | 2.499 | 2 | 13 | 319 |
GO:0005524 | ATP binding | 4.95e-02 | 1.00e+00 | 1.474 | 4 | 60 | 1298 |
GO:0045444 | fat cell differentiation | 5.09e-02 | 1.00e+00 | 4.261 | 1 | 2 | 47 |
GO:0045732 | positive regulation of protein catabolic process | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 3 | 50 |
GO:0006879 | cellular iron ion homeostasis | 5.51e-02 | 1.00e+00 | 4.144 | 1 | 4 | 51 |
GO:0003725 | double-stranded RNA binding | 5.62e-02 | 1.00e+00 | 4.116 | 1 | 5 | 52 |
GO:0000226 | microtubule cytoskeleton organization | 5.62e-02 | 1.00e+00 | 4.116 | 1 | 3 | 52 |
GO:0007623 | circadian rhythm | 5.72e-02 | 1.00e+00 | 4.088 | 1 | 1 | 53 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.72e-02 | 1.00e+00 | 4.088 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 54 |
GO:0002244 | hematopoietic progenitor cell differentiation | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 54 |
GO:0002039 | p53 binding | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 7 | 55 |
GO:0012505 | endomembrane system | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 2 | 56 |
GO:0005925 | focal adhesion | 6.10e-02 | 1.00e+00 | 2.300 | 2 | 19 | 366 |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 6.35e-02 | 1.00e+00 | 3.933 | 1 | 2 | 59 |
GO:0008013 | beta-catenin binding | 6.46e-02 | 1.00e+00 | 3.909 | 1 | 3 | 60 |
GO:0071260 | cellular response to mechanical stimulus | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 5 | 65 |
GO:0034329 | cell junction assembly | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 1 | 68 |
GO:0018105 | peptidyl-serine phosphorylation | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 5 | 69 |
GO:0046474 | glycerophospholipid biosynthetic process | 7.49e-02 | 1.00e+00 | 3.687 | 1 | 4 | 70 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.90e-02 | 1.00e+00 | 3.607 | 1 | 6 | 74 |
GO:0060070 | canonical Wnt signaling pathway | 8.01e-02 | 1.00e+00 | 3.587 | 1 | 3 | 75 |
GO:0071013 | catalytic step 2 spliceosome | 8.31e-02 | 1.00e+00 | 3.531 | 1 | 4 | 78 |
GO:0001726 | ruffle | 8.52e-02 | 1.00e+00 | 3.494 | 1 | 4 | 80 |
GO:0019083 | viral transcription | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 10 | 81 |
GO:0043197 | dendritic spine | 8.72e-02 | 1.00e+00 | 3.459 | 1 | 3 | 82 |
GO:0005681 | spliceosomal complex | 8.82e-02 | 1.00e+00 | 3.441 | 1 | 4 | 83 |
GO:0006898 | receptor-mediated endocytosis | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 3 | 84 |
GO:0009887 | organ morphogenesis | 9.13e-02 | 1.00e+00 | 3.390 | 1 | 2 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 9.13e-02 | 1.00e+00 | 3.390 | 1 | 1 | 86 |
GO:0006415 | translational termination | 9.23e-02 | 1.00e+00 | 3.373 | 1 | 10 | 87 |
GO:0016310 | phosphorylation | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 4 | 90 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 7 | 90 |
GO:0006928 | cellular component movement | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 7 | 91 |
GO:0005737 | cytoplasm | 9.70e-02 | 1.00e+00 | 0.744 | 7 | 110 | 3767 |
GO:0001649 | osteoblast differentiation | 9.74e-02 | 1.00e+00 | 3.293 | 1 | 6 | 92 |
GO:0005730 | nucleolus | 9.98e-02 | 1.00e+00 | 1.136 | 4 | 69 | 1641 |
GO:0030426 | growth cone | 1.01e-01 | 1.00e+00 | 3.231 | 1 | 5 | 96 |
GO:0005178 | integrin binding | 1.01e-01 | 1.00e+00 | 3.231 | 1 | 2 | 96 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.09e-01 | 1.00e+00 | 3.116 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 1.15e-01 | 1.00e+00 | 3.035 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 1.16e-01 | 1.00e+00 | 3.022 | 1 | 3 | 111 |
GO:0048015 | phosphatidylinositol-mediated signaling | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 7 | 114 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 1.20e-01 | 1.00e+00 | 2.971 | 1 | 13 | 115 |
GO:0006325 | chromatin organization | 1.23e-01 | 1.00e+00 | 2.933 | 1 | 5 | 118 |
GO:0009615 | response to virus | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0016477 | cell migration | 1.33e-01 | 1.00e+00 | 2.816 | 1 | 5 | 128 |
GO:0006644 | phospholipid metabolic process | 1.34e-01 | 1.00e+00 | 2.805 | 1 | 5 | 129 |
GO:0000790 | nuclear chromatin | 1.34e-01 | 1.00e+00 | 2.805 | 1 | 9 | 129 |
GO:0006413 | translational initiation | 1.36e-01 | 1.00e+00 | 2.783 | 1 | 17 | 131 |
GO:0031982 | vesicle | 1.36e-01 | 1.00e+00 | 2.783 | 1 | 9 | 131 |
GO:0045087 | innate immune response | 1.40e-01 | 1.00e+00 | 1.597 | 2 | 24 | 596 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.41e-01 | 1.00e+00 | 2.729 | 1 | 9 | 136 |
GO:0003735 | structural constituent of ribosome | 1.42e-01 | 1.00e+00 | 2.718 | 1 | 10 | 137 |
GO:0008286 | insulin receptor signaling pathway | 1.46e-01 | 1.00e+00 | 2.666 | 1 | 7 | 142 |
GO:0006457 | protein folding | 1.47e-01 | 1.00e+00 | 2.656 | 1 | 7 | 143 |
GO:0010628 | positive regulation of gene expression | 1.50e-01 | 1.00e+00 | 2.626 | 1 | 5 | 146 |
GO:0005198 | structural molecule activity | 1.54e-01 | 1.00e+00 | 2.587 | 1 | 5 | 150 |
GO:0045121 | membrane raft | 1.60e-01 | 1.00e+00 | 2.531 | 1 | 8 | 156 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.60e-01 | 1.00e+00 | 2.531 | 1 | 9 | 156 |
GO:0006397 | mRNA processing | 1.64e-01 | 1.00e+00 | 2.494 | 1 | 2 | 160 |
GO:0000398 | mRNA splicing, via spliceosome | 1.67e-01 | 1.00e+00 | 2.459 | 1 | 8 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.68e-01 | 1.00e+00 | 2.450 | 1 | 7 | 165 |
GO:0030424 | axon | 1.69e-01 | 1.00e+00 | 2.441 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.71e-01 | 1.00e+00 | 2.424 | 1 | 12 | 168 |
GO:0006886 | intracellular protein transport | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 5 | 171 |
GO:0016607 | nuclear speck | 1.75e-01 | 1.00e+00 | 2.390 | 1 | 3 | 172 |
GO:0031625 | ubiquitin protein ligase binding | 1.80e-01 | 1.00e+00 | 2.340 | 1 | 14 | 178 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 12 | 189 |
GO:0005765 | lysosomal membrane | 2.03e-01 | 1.00e+00 | 2.151 | 1 | 5 | 203 |
GO:0008380 | RNA splicing | 2.25e-01 | 1.00e+00 | 1.983 | 1 | 11 | 228 |
GO:0043025 | neuronal cell body | 2.40e-01 | 1.00e+00 | 1.879 | 1 | 9 | 245 |
GO:0005975 | carbohydrate metabolic process | 2.47e-01 | 1.00e+00 | 1.833 | 1 | 9 | 253 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.60e-01 | 1.00e+00 | 1.745 | 1 | 15 | 269 |
GO:0042493 | response to drug | 2.73e-01 | 1.00e+00 | 1.666 | 1 | 13 | 284 |
GO:0005856 | cytoskeleton | 2.78e-01 | 1.00e+00 | 1.631 | 1 | 12 | 291 |
GO:0035556 | intracellular signal transduction | 2.88e-01 | 1.00e+00 | 1.573 | 1 | 9 | 303 |
GO:0004674 | protein serine/threonine kinase activity | 2.92e-01 | 1.00e+00 | 1.549 | 1 | 12 | 308 |
GO:0043231 | intracellular membrane-bounded organelle | 3.00e-01 | 1.00e+00 | 1.503 | 1 | 9 | 318 |
GO:0008283 | cell proliferation | 3.08e-01 | 1.00e+00 | 1.459 | 1 | 14 | 328 |
GO:0005886 | plasma membrane | 3.18e-01 | 1.00e+00 | 0.482 | 4 | 45 | 2582 |
GO:0003723 | RNA binding | 3.19e-01 | 1.00e+00 | 1.398 | 1 | 20 | 342 |
GO:0007155 | cell adhesion | 3.40e-01 | 1.00e+00 | 1.289 | 1 | 6 | 369 |
GO:0055114 | oxidation-reduction process | 3.77e-01 | 1.00e+00 | 1.102 | 1 | 12 | 420 |
GO:0055085 | transmembrane transport | 3.88e-01 | 1.00e+00 | 1.051 | 1 | 10 | 435 |
GO:0007596 | blood coagulation | 4.01e-01 | 1.00e+00 | 0.986 | 1 | 18 | 455 |
GO:0006468 | protein phosphorylation | 4.05e-01 | 1.00e+00 | 0.971 | 1 | 18 | 460 |
GO:0048471 | perinuclear region of cytoplasm | 4.33e-01 | 1.00e+00 | 0.845 | 1 | 13 | 502 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 5.94e-01 | 1.00e+00 | 0.192 | 1 | 19 | 789 |
GO:0005615 | extracellular space | 6.67e-01 | 1.00e+00 | -0.086 | 1 | 17 | 957 |
GO:0016021 | integral component of membrane | 9.06e-01 | 1.00e+00 | -1.137 | 1 | 27 | 1982 |