reg-snw-10459

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.798	2.82e-06	5.23e-03	9.35e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-10459 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
EIF2S2	8894	8	1.075	0.940	22	-	Yes	-
[ MAD2L2 ]	10459	1	0.270	0.798	21	-	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
E2F3	1871	1	-0.413	0.798	33	TF	-	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	MAD2L2	10459	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
E2F3	1871	MAD2L2	10459	pd	>	reg.ITFP.txt: no annot

Related GO terms (103)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000278	mitotic cell cycle	3.40e-05	3.32e-01	4.151	4	35	314
GO:0005654	nucleoplasm	1.03e-04	1.00e+00	2.993	5	55	876
GO:0010467	gene expression	2.73e-04	1.00e+00	3.383	4	31	535
GO:0006521	regulation of cellular amino acid metabolic process	3.56e-04	1.00e+00	6.088	2	16	41
GO:0000502	proteasome complex	4.69e-04	1.00e+00	5.891	2	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.74e-04	1.00e+00	5.746	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.97e-04	1.00e+00	5.718	2	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.66e-04	1.00e+00	5.639	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.90e-04	1.00e+00	5.613	2	16	57
GO:0042772	DNA damage response, signal transduction resulting in transcription	7.17e-04	1.00e+00	10.446	1	1	1
GO:0016035	zeta DNA polymerase complex	7.17e-04	1.00e+00	10.446	1	1	1
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.64e-04	1.00e+00	5.539	2	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.90e-04	1.00e+00	5.515	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.97e-04	1.00e+00	5.424	2	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.04e-03	1.00e+00	5.317	2	16	70
GO:0002176	male germ cell proliferation	1.43e-03	1.00e+00	9.446	1	1	2
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	1.43e-03	1.00e+00	9.446	1	1	2
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	1.43e-03	1.00e+00	9.446	1	1	2
GO:0000209	protein polyubiquitination	1.79e-03	1.00e+00	4.922	2	16	92
GO:0005850	eukaryotic translation initiation factor 2 complex	2.15e-03	1.00e+00	8.861	1	1	3
GO:0034641	cellular nitrogen compound metabolic process	2.32e-03	1.00e+00	4.732	2	18	105
GO:0005515	protein binding	2.39e-03	1.00e+00	1.244	7	76	4124
GO:0042981	regulation of apoptotic process	2.64e-03	1.00e+00	4.639	2	18	112
GO:0000212	meiotic spindle organization	2.86e-03	1.00e+00	8.446	1	1	4
GO:0043248	proteasome assembly	2.86e-03	1.00e+00	8.446	1	1	4
GO:0003924	GTPase activity	2.97e-03	1.00e+00	4.551	2	3	119
GO:0000082	G1/S transition of mitotic cell cycle	3.27e-03	1.00e+00	4.480	2	24	125
GO:0006184	GTP catabolic process	3.54e-03	1.00e+00	4.424	2	3	130
GO:0005827	polar microtubule	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0008432	JUN kinase binding	4.29e-03	1.00e+00	7.861	1	1	6
GO:0010944	negative regulation of transcription by competitive promoter binding	5.72e-03	1.00e+00	7.446	1	1	8
GO:0031122	cytoplasmic microtubule organization	5.72e-03	1.00e+00	7.446	1	2	8
GO:0016071	mRNA metabolic process	5.97e-03	1.00e+00	4.037	2	21	170
GO:0005838	proteasome regulatory particle	7.15e-03	1.00e+00	7.124	1	4	10
GO:0016070	RNA metabolic process	7.27e-03	1.00e+00	3.891	2	21	188
GO:2000678	negative regulation of transcription regulatory region DNA binding	7.86e-03	1.00e+00	6.987	1	1	11
GO:0007020	microtubule nucleation	7.86e-03	1.00e+00	6.987	1	1	11
GO:0005525	GTP binding	7.95e-03	1.00e+00	3.824	2	5	197
GO:0048863	stem cell differentiation	8.57e-03	1.00e+00	6.861	1	1	12
GO:0005680	anaphase-promoting complex	9.28e-03	1.00e+00	6.746	1	2	13
GO:0010243	response to organonitrogen compound	1.00e-02	1.00e+00	6.639	1	1	14
GO:0022624	proteasome accessory complex	1.00e-02	1.00e+00	6.639	1	7	14
GO:0010719	negative regulation of epithelial to mesenchymal transition	1.07e-02	1.00e+00	6.539	1	1	15
GO:0008135	translation factor activity, nucleic acid binding	1.07e-02	1.00e+00	6.539	1	1	15
GO:0005839	proteasome core complex	1.14e-02	1.00e+00	6.446	1	9	16
GO:0004298	threonine-type endopeptidase activity	1.21e-02	1.00e+00	6.359	1	9	17
GO:0000794	condensed nuclear chromosome	1.28e-02	1.00e+00	6.276	1	3	18
GO:0042177	negative regulation of protein catabolic process	1.43e-02	1.00e+00	6.124	1	1	20
GO:0007015	actin filament organization	1.71e-02	1.00e+00	5.861	1	1	24
GO:0007094	mitotic spindle assembly checkpoint	1.78e-02	1.00e+00	5.802	1	3	25
GO:0043066	negative regulation of apoptotic process	2.04e-02	1.00e+00	3.115	2	20	322
GO:0001102	RNA polymerase II activating transcription factor binding	2.20e-02	1.00e+00	5.492	1	2	31
GO:0015030	Cajal body	2.27e-02	1.00e+00	5.446	1	2	32
GO:0014070	response to organic cyclic compound	2.41e-02	1.00e+00	5.359	1	1	34
GO:0005829	cytosol	2.45e-02	1.00e+00	1.643	4	58	1787
GO:0000226	microtubule cytoskeleton organization	2.55e-02	1.00e+00	5.276	1	2	36
GO:0003743	translation initiation factor activity	2.62e-02	1.00e+00	5.237	1	2	37
GO:0045893	positive regulation of transcription, DNA-templated	2.74e-02	1.00e+00	2.888	2	10	377
GO:0001047	core promoter binding	2.97e-02	1.00e+00	5.054	1	2	42
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	3.18e-02	1.00e+00	4.954	1	2	45
GO:0006915	apoptotic process	3.22e-02	1.00e+00	2.763	2	21	411
GO:0033138	positive regulation of peptidyl-serine phosphorylation	3.39e-02	1.00e+00	4.861	1	1	48
GO:0001558	regulation of cell growth	3.46e-02	1.00e+00	4.831	1	2	49
GO:0016032	viral process	3.48e-02	1.00e+00	2.705	2	32	428
GO:0006302	double-strand break repair	3.67e-02	1.00e+00	4.746	1	8	52
GO:0005681	spliceosomal complex	3.88e-02	1.00e+00	4.665	1	2	55
GO:0008584	male gonad development	4.02e-02	1.00e+00	4.613	1	2	57
GO:0090090	negative regulation of canonical Wnt signaling pathway	4.15e-02	1.00e+00	4.563	1	2	59
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0005634	nucleus	4.47e-02	1.00e+00	1.104	5	67	3246
GO:0016020	membrane	4.49e-02	1.00e+00	1.794	3	38	1207
GO:0005730	nucleolus	4.59e-02	1.00e+00	1.782	3	41	1217
GO:0005200	structural constituent of cytoskeleton	4.78e-02	1.00e+00	4.359	1	2	68
GO:0005819	spindle	5.60e-02	1.00e+00	4.124	1	4	80
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	2	92
GO:0007219	Notch signaling pathway	6.62e-02	1.00e+00	3.876	1	4	95
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	5	97
GO:0006413	translational initiation	6.89e-02	1.00e+00	3.817	1	4	99
GO:0006397	mRNA processing	7.63e-02	1.00e+00	3.665	1	2	110
GO:0016607	nuclear speck	8.43e-02	1.00e+00	3.515	1	3	122
GO:0000398	mRNA splicing, via spliceosome	8.83e-02	1.00e+00	3.446	1	8	128
GO:0005737	cytoplasm	9.00e-02	1.00e+00	1.084	4	50	2633
GO:0005667	transcription factor complex	1.01e-01	1.00e+00	3.246	1	3	147
GO:0001701	in utero embryonic development	1.05e-01	1.00e+00	3.179	1	3	154
GO:0044822	poly(A) RNA binding	1.07e-01	1.00e+00	1.804	2	25	799
GO:0006367	transcription initiation from RNA polymerase II promoter	1.10e-01	1.00e+00	3.115	1	4	161
GO:0007067	mitotic nuclear division	1.12e-01	1.00e+00	3.080	1	8	165
GO:0008380	RNA splicing	1.12e-01	1.00e+00	3.080	1	7	165
GO:0044281	small molecule metabolic process	1.17e-01	1.00e+00	1.725	2	32	844
GO:0006412	translation	1.21e-01	1.00e+00	2.970	1	3	178
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	19	203
GO:0043231	intracellular membrane-bounded organelle	1.46e-01	1.00e+00	2.678	1	7	218
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	8	217
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	11	247
GO:0008284	positive regulation of cell proliferation	1.84e-01	1.00e+00	2.322	1	2	279
GO:0044267	cellular protein metabolic process	2.27e-01	1.00e+00	1.987	1	5	352
GO:0005794	Golgi apparatus	2.62e-01	1.00e+00	1.749	1	5	415
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.85e-01	1.00e+00	1.613	1	4	456
GO:0070062	extracellular vesicular exosome	3.34e-01	1.00e+00	0.766	2	43	1641
GO:0003700	sequence-specific DNA binding transcription factor activity	3.50e-01	1.00e+00	1.261	1	6	582
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0006351	transcription, DNA-templated	5.58e-01	1.00e+00	0.375	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-10459

Statistics

Genes (7)

Interactions (6)

Related GO terms (103)