reg-snw-56655

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-56655 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA2	5683	1	1.093	0.828	19	-	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
VARS	7407	7	0.549	0.938	124	TF	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
[ POLE4 ]	56655	1	0.177	0.828	56	TF	-	-
PSMB3	5691	2	0.668	0.901	19	-	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot

Related GO terms (82)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	5.63e-11	5.49e-07	7.218	5	16	41
GO:0000502	proteasome complex	1.15e-10	1.12e-06	7.021	5	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.95e-10	1.90e-06	6.875	5	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.15e-10	2.10e-06	6.847	5	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.86e-10	2.79e-06	6.768	5	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.13e-10	3.06e-06	6.742	5	16	57
GO:0005839	proteasome core complex	3.35e-10	3.27e-06	8.253	4	9	16
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.08e-10	3.98e-06	6.668	5	17	60
GO:0004298	threonine-type endopeptidase activity	4.38e-10	4.28e-06	8.166	4	9	17
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.44e-10	4.34e-06	6.645	5	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.16e-10	6.02e-06	6.553	5	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.02e-10	8.81e-06	6.446	5	16	70
GO:0000209	protein polyubiquitination	3.64e-09	3.56e-05	6.052	5	16	92
GO:0034641	cellular nitrogen compound metabolic process	7.13e-09	6.96e-05	5.861	5	18	105
GO:0042981	regulation of apoptotic process	9.89e-09	9.66e-05	5.768	5	18	112
GO:0000082	G1/S transition of mitotic cell cycle	1.72e-08	1.68e-04	5.610	5	24	125
GO:0016071	mRNA metabolic process	8.10e-08	7.91e-04	5.166	5	21	170
GO:0016070	RNA metabolic process	1.34e-07	1.31e-03	5.021	5	21	188
GO:0016032	viral process	1.78e-07	1.74e-03	4.097	6	32	428
GO:0010467	gene expression	6.70e-07	6.55e-03	3.775	6	31	535
GO:0000278	mitotic cell cycle	1.72e-06	1.68e-02	4.281	5	35	314
GO:0043066	negative regulation of apoptotic process	1.95e-06	1.91e-02	4.244	5	20	322
GO:0006915	apoptotic process	6.50e-06	6.35e-02	3.892	5	21	411
GO:0005654	nucleoplasm	1.23e-05	1.20e-01	3.064	6	55	876
GO:0005829	cytosol	4.58e-05	4.47e-01	2.257	7	58	1787
GO:0044281	small molecule metabolic process	2.14e-04	1.00e+00	2.854	5	32	844
GO:0004832	valine-tRNA ligase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0006438	valyl-tRNA aminoacylation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0030891	VCB complex	1.64e-03	1.00e+00	9.253	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.64e-03	1.00e+00	9.253	1	1	2
GO:0008622	epsilon DNA polymerase complex	2.46e-03	1.00e+00	8.668	1	1	3
GO:0019788	NEDD8 ligase activity	3.27e-03	1.00e+00	8.253	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	3.27e-03	1.00e+00	8.253	1	2	4
GO:0043248	proteasome assembly	3.27e-03	1.00e+00	8.253	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.09e-03	1.00e+00	7.931	1	2	5
GO:0002161	aminoacyl-tRNA editing activity	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070062	extracellular vesicular exosome	4.77e-03	1.00e+00	1.895	5	43	1641
GO:0019773	proteasome core complex, alpha-subunit complex	4.91e-03	1.00e+00	7.668	1	4	6
GO:0031462	Cul2-RING ubiquitin ligase complex	4.91e-03	1.00e+00	7.668	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	4.91e-03	1.00e+00	7.668	1	1	6
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	5.72e-03	1.00e+00	7.446	1	2	7
GO:0045116	protein neddylation	5.72e-03	1.00e+00	7.446	1	1	7
GO:0006450	regulation of translational fidelity	6.54e-03	1.00e+00	7.253	1	1	8
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	7.35e-03	1.00e+00	7.083	1	1	9
GO:0005838	proteasome regulatory particle	8.17e-03	1.00e+00	6.931	1	4	10
GO:0048863	stem cell differentiation	9.79e-03	1.00e+00	6.668	1	1	12
GO:0010243	response to organonitrogen compound	1.14e-02	1.00e+00	6.446	1	1	14
GO:0022624	proteasome accessory complex	1.14e-02	1.00e+00	6.446	1	7	14
GO:0005515	protein binding	1.21e-02	1.00e+00	1.051	7	76	4124
GO:0003887	DNA-directed DNA polymerase activity	1.30e-02	1.00e+00	6.253	1	2	16
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.30e-02	1.00e+00	6.253	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	1.30e-02	1.00e+00	6.253	1	1	16
GO:0006513	protein monoubiquitination	1.38e-02	1.00e+00	6.166	1	1	17
GO:0019005	SCF ubiquitin ligase complex	1.63e-02	1.00e+00	5.931	1	1	20
GO:0071897	DNA biosynthetic process	1.63e-02	1.00e+00	5.931	1	2	20
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.79e-02	1.00e+00	5.794	1	1	22
GO:0005634	nucleus	1.93e-02	1.00e+00	1.174	6	67	3246
GO:0043966	histone H3 acetylation	2.27e-02	1.00e+00	5.446	1	1	28
GO:0006418	tRNA aminoacylation for protein translation	2.35e-02	1.00e+00	5.395	1	1	29
GO:0014070	response to organic cyclic compound	2.75e-02	1.00e+00	5.166	1	1	34
GO:0000932	cytoplasmic mRNA processing body	3.47e-02	1.00e+00	4.827	1	2	43
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	4.50e-02	1.00e+00	4.446	1	3	56
GO:0015630	microtubule cytoskeleton	5.98e-02	1.00e+00	4.025	1	2	75
GO:0071456	cellular response to hypoxia	6.06e-02	1.00e+00	4.005	1	2	76
GO:0006511	ubiquitin-dependent protein catabolic process	7.30e-02	1.00e+00	3.730	1	2	92
GO:0007219	Notch signaling pathway	7.53e-02	1.00e+00	3.684	1	4	95
GO:0009615	response to virus	7.68e-02	1.00e+00	3.653	1	3	97
GO:0005739	mitochondrion	9.71e-02	1.00e+00	1.889	2	11	659
GO:0032403	protein complex binding	1.02e-01	1.00e+00	3.231	1	2	130
GO:0015629	actin cytoskeleton	1.06e-01	1.00e+00	3.166	1	2	136
GO:0031625	ubiquitin protein ligase binding	1.08e-01	1.00e+00	3.145	1	5	138
GO:0004842	ubiquitin-protein transferase activity	1.38e-01	1.00e+00	2.770	1	2	179
GO:0016567	protein ubiquitination	1.44e-01	1.00e+00	2.699	1	3	188
GO:0006281	DNA repair	1.55e-01	1.00e+00	2.588	1	19	203
GO:0046982	protein heterodimerization activity	1.98e-01	1.00e+00	2.204	1	5	265
GO:0043565	sequence-specific DNA binding	2.04e-01	1.00e+00	2.150	1	1	275
GO:0016020	membrane	2.59e-01	1.00e+00	1.016	2	38	1207
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	41	1217
GO:0005794	Golgi apparatus	2.94e-01	1.00e+00	1.556	1	5	415
GO:0008270	zinc ion binding	4.62e-01	1.00e+00	0.748	1	7	727
GO:0005524	ATP binding	5.35e-01	1.00e+00	0.453	1	23	892
GO:0005737	cytoplasm	9.19e-01	1.00e+00	-1.109	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-56655

Statistics

Genes (8)

Interactions (8)

Related GO terms (82)