reg-snw-6723

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.840	5.77e-07	2.25e-03	4.41e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-6723 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ SRM ]	6723	1	-0.064	0.840	32	-	-	-
CAD	790	25	0.807	0.973	67	-	-	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
POLR2F	5435	14	0.891	0.956	5	-	Yes	-
PHB2	11331	8	0.829	0.956	11	-	Yes	-
PSMD3	5709	9	0.986	0.938	55	TF	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
VARS	7407	7	0.549	0.938	124	TF	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
FBL	2091	9	0.839	0.956	14	-	Yes	-

Interactions (22)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
FBL	2091	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	PHB2	11331	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
SRM	6723	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
SRM	6723	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
SRM	6723	VARS	7407	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot

Related GO terms (194)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016363	nuclear matrix	1.95e-06	1.91e-02	5.363	4	7	73
GO:0010467	gene expression	3.24e-05	3.17e-01	3.075	6	31	535
GO:0000812	Swr1 complex	3.42e-05	3.34e-01	7.746	2	2	7
GO:0016020	membrane	3.86e-05	3.77e-01	2.316	8	38	1207
GO:0005730	nucleolus	4.10e-05	4.01e-01	2.304	8	41	1217
GO:0031011	Ino80 complex	4.56e-05	4.45e-01	7.553	2	2	8
GO:0005654	nucleoplasm	4.83e-05	4.72e-01	2.586	7	55	876
GO:0043968	histone H2A acetylation	7.32e-05	7.15e-01	7.231	2	2	10
GO:0035267	NuA4 histone acetyltransferase complex	1.07e-04	1.00e+00	6.968	2	3	12
GO:0003678	DNA helicase activity	2.47e-04	1.00e+00	6.383	2	3	18
GO:0071339	MLL1 complex	2.47e-04	1.00e+00	6.383	2	2	18
GO:0034641	cellular nitrogen compound metabolic process	3.19e-04	1.00e+00	4.424	3	18	105
GO:0070062	extracellular vesicular exosome	3.62e-04	1.00e+00	1.873	8	43	1641
GO:0043967	histone H4 acetylation	3.72e-04	1.00e+00	6.094	2	2	22
GO:0000398	mRNA splicing, via spliceosome	5.72e-04	1.00e+00	4.138	3	8	128
GO:0005829	cytosol	6.63e-04	1.00e+00	1.750	8	58	1787
GO:0015030	Cajal body	7.93e-04	1.00e+00	5.553	2	2	32
GO:0040008	regulation of growth	1.06e-03	1.00e+00	5.344	2	2	37
GO:0032508	DNA duplex unwinding	1.12e-03	1.00e+00	5.305	2	5	38
GO:0008380	RNA splicing	1.20e-03	1.00e+00	3.772	3	7	165
GO:0006521	regulation of cellular amino acid metabolic process	1.30e-03	1.00e+00	5.195	2	16	41
GO:1990259	histone-glutamine methyltransferase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0004832	valine-tRNA ligase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0008295	spermidine biosynthetic process	1.33e-03	1.00e+00	9.553	1	1	1
GO:1990258	histone glutamine methylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0004151	dihydroorotase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0004766	spermidine synthase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0070335	aspartate binding	1.33e-03	1.00e+00	9.553	1	1	1
GO:0016074	snoRNA metabolic process	1.33e-03	1.00e+00	9.553	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	1.33e-03	1.00e+00	9.553	1	1	1
GO:0005634	nucleus	1.60e-03	1.00e+00	1.210	10	67	3246
GO:0000502	proteasome complex	1.71e-03	1.00e+00	4.998	2	17	47
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.86e-03	1.00e+00	4.938	2	3	49
GO:0006310	DNA recombination	1.93e-03	1.00e+00	4.909	2	6	50
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.09e-03	1.00e+00	4.853	2	17	52
GO:0006281	DNA repair	2.17e-03	1.00e+00	3.473	3	19	203
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.17e-03	1.00e+00	4.825	2	17	53
GO:0005681	spliceosomal complex	2.33e-03	1.00e+00	4.772	2	2	55
GO:0043234	protein complex	2.39e-03	1.00e+00	3.424	3	8	210
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.42e-03	1.00e+00	4.746	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.51e-03	1.00e+00	4.720	2	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.77e-03	1.00e+00	4.646	2	17	60
GO:0071013	catalytic step 2 spliceosome	2.86e-03	1.00e+00	4.622	2	5	61
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.86e-03	1.00e+00	4.622	2	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.25e-03	1.00e+00	4.531	2	17	65
GO:0006325	chromatin organization	3.75e-03	1.00e+00	4.424	2	3	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.75e-03	1.00e+00	4.424	2	16	70
GO:0071733	transcriptional activation by promoter-enhancer looping	3.99e-03	1.00e+00	7.968	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	3.99e-03	1.00e+00	7.968	1	1	3
GO:0006543	glutamine catabolic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0001652	granular component	3.99e-03	1.00e+00	7.968	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	3.99e-03	1.00e+00	7.968	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0031428	box C/D snoRNP complex	3.99e-03	1.00e+00	7.968	1	1	3
GO:0001649	osteoblast differentiation	4.19e-03	1.00e+00	4.344	2	2	74
GO:0030529	ribonucleoprotein complex	5.12e-03	1.00e+00	4.195	2	4	82
GO:0051414	response to cortisol	5.32e-03	1.00e+00	7.553	1	1	4
GO:0000212	meiotic spindle organization	5.32e-03	1.00e+00	7.553	1	1	4
GO:0071169	establishment of protein localization to chromatin	5.32e-03	1.00e+00	7.553	1	1	4
GO:0006228	UTP biosynthetic process	5.32e-03	1.00e+00	7.553	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	5.32e-03	1.00e+00	7.553	1	1	4
GO:0000209	protein polyubiquitination	6.40e-03	1.00e+00	4.029	2	16	92
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	6.64e-03	1.00e+00	7.231	1	1	5
GO:0014075	response to amine	6.64e-03	1.00e+00	7.231	1	1	5
GO:0060744	mammary gland branching involved in thelarche	6.64e-03	1.00e+00	7.231	1	1	5
GO:0005827	polar microtubule	6.64e-03	1.00e+00	7.231	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0000930	gamma-tubulin complex	6.64e-03	1.00e+00	7.231	1	1	5
GO:0000278	mitotic cell cycle	7.41e-03	1.00e+00	2.843	3	35	314
GO:0016887	ATPase activity	7.52e-03	1.00e+00	3.909	2	6	100
GO:0001055	RNA polymerase II activity	7.96e-03	1.00e+00	6.968	1	2	6
GO:0046134	pyrimidine nucleoside biosynthetic process	7.96e-03	1.00e+00	6.968	1	1	6
GO:0031000	response to caffeine	7.96e-03	1.00e+00	6.968	1	1	6
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	9.28e-03	1.00e+00	6.746	1	1	7
GO:0042981	regulation of apoptotic process	9.36e-03	1.00e+00	3.746	2	18	112
GO:0042802	identical protein binding	1.03e-02	1.00e+00	2.670	3	7	354
GO:0003924	GTPase activity	1.05e-02	1.00e+00	3.658	2	3	119
GO:0006450	regulation of translational fidelity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0031122	cytoplasmic microtubule organization	1.06e-02	1.00e+00	6.553	1	2	8
GO:0006595	polyamine metabolic process	1.06e-02	1.00e+00	6.553	1	1	8
GO:0000082	G1/S transition of mitotic cell cycle	1.16e-02	1.00e+00	3.587	2	24	125
GO:0008266	poly(U) RNA binding	1.19e-02	1.00e+00	6.383	1	1	9
GO:0006184	GTP catabolic process	1.25e-02	1.00e+00	3.531	2	3	130
GO:0005736	DNA-directed RNA polymerase I complex	1.32e-02	1.00e+00	6.231	1	2	10
GO:0006541	glutamine metabolic process	1.32e-02	1.00e+00	6.231	1	1	10
GO:0001054	RNA polymerase I activity	1.32e-02	1.00e+00	6.231	1	2	10
GO:0005838	proteasome regulatory particle	1.32e-02	1.00e+00	6.231	1	4	10
GO:0007020	microtubule nucleation	1.46e-02	1.00e+00	6.094	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.46e-02	1.00e+00	6.094	1	2	11
GO:0030234	enzyme regulator activity	1.46e-02	1.00e+00	6.094	1	2	11
GO:0045120	pronucleus	1.46e-02	1.00e+00	6.094	1	1	11
GO:0071392	cellular response to estradiol stimulus	1.72e-02	1.00e+00	5.853	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	1.72e-02	1.00e+00	5.853	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.72e-02	1.00e+00	5.853	1	2	13
GO:0001056	RNA polymerase III activity	1.72e-02	1.00e+00	5.853	1	2	13
GO:0035066	positive regulation of histone acetylation	1.72e-02	1.00e+00	5.853	1	1	13
GO:0060749	mammary gland alveolus development	1.72e-02	1.00e+00	5.853	1	1	13
GO:0016032	viral process	1.72e-02	1.00e+00	2.396	3	32	428
GO:0006386	termination of RNA polymerase III transcription	1.85e-02	1.00e+00	5.746	1	2	14
GO:0010243	response to organonitrogen compound	1.85e-02	1.00e+00	5.746	1	1	14
GO:0042176	regulation of protein catabolic process	1.85e-02	1.00e+00	5.746	1	2	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.85e-02	1.00e+00	5.746	1	2	14
GO:0022624	proteasome accessory complex	1.85e-02	1.00e+00	5.746	1	7	14
GO:0016071	mRNA metabolic process	2.07e-02	1.00e+00	3.144	2	21	170
GO:0044281	small molecule metabolic process	2.10e-02	1.00e+00	1.832	4	32	844
GO:0005719	nuclear euchromatin	2.11e-02	1.00e+00	5.553	1	1	16
GO:0005839	proteasome core complex	2.11e-02	1.00e+00	5.553	1	9	16
GO:0006206	pyrimidine nucleobase metabolic process	2.24e-02	1.00e+00	5.466	1	2	17
GO:0004298	threonine-type endopeptidase activity	2.24e-02	1.00e+00	5.466	1	9	17
GO:0071364	cellular response to epidermal growth factor stimulus	2.37e-02	1.00e+00	5.383	1	1	18
GO:0033574	response to testosterone	2.37e-02	1.00e+00	5.383	1	1	18
GO:0000794	condensed nuclear chromosome	2.37e-02	1.00e+00	5.383	1	3	18
GO:0016070	RNA metabolic process	2.50e-02	1.00e+00	2.998	2	21	188
GO:0005524	ATP binding	2.53e-02	1.00e+00	1.752	4	23	892
GO:0043044	ATP-dependent chromatin remodeling	2.63e-02	1.00e+00	5.231	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	2.63e-02	1.00e+00	5.231	1	2	20
GO:0005525	GTP binding	2.73e-02	1.00e+00	2.931	2	5	197
GO:0017144	drug metabolic process	2.76e-02	1.00e+00	5.161	1	1	21
GO:0030331	estrogen receptor binding	2.89e-02	1.00e+00	5.094	1	1	22
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	2	24
GO:0004003	ATP-dependent DNA helicase activity	3.28e-02	1.00e+00	4.909	1	2	25
GO:0008033	tRNA processing	3.28e-02	1.00e+00	4.909	1	1	25
GO:0003730	mRNA 3'-UTR binding	3.28e-02	1.00e+00	4.909	1	2	25
GO:0031492	nucleosomal DNA binding	3.28e-02	1.00e+00	4.909	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	3.54e-02	1.00e+00	4.798	1	2	27
GO:0034644	cellular response to UV	3.67e-02	1.00e+00	4.746	1	2	28
GO:0006418	tRNA aminoacylation for protein translation	3.79e-02	1.00e+00	4.695	1	1	29
GO:0018107	peptidyl-threonine phosphorylation	3.79e-02	1.00e+00	4.695	1	2	29
GO:0006383	transcription from RNA polymerase III promoter	3.79e-02	1.00e+00	4.695	1	2	29
GO:0043195	terminal bouton	4.05e-02	1.00e+00	4.599	1	1	31
GO:0031490	chromatin DNA binding	4.05e-02	1.00e+00	4.599	1	1	31
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	11	247
GO:0007595	lactation	4.18e-02	1.00e+00	4.553	1	2	32
GO:0014070	response to organic cyclic compound	4.44e-02	1.00e+00	4.466	1	1	34
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	2	35
GO:0000226	microtubule cytoskeleton organization	4.69e-02	1.00e+00	4.383	1	2	36
GO:0035690	cellular response to drug	4.95e-02	1.00e+00	4.305	1	2	38
GO:0006283	transcription-coupled nucleotide-excision repair	5.20e-02	1.00e+00	4.231	1	6	40
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5.20e-02	1.00e+00	4.231	1	2	40
GO:0042995	cell projection	5.33e-02	1.00e+00	4.195	1	2	41
GO:0003684	damaged DNA binding	5.33e-02	1.00e+00	4.195	1	9	41
GO:0031100	organ regeneration	5.71e-02	1.00e+00	4.094	1	2	44
GO:0032481	positive regulation of type I interferon production	6.21e-02	1.00e+00	3.968	1	5	48
GO:0006334	nucleosome assembly	6.58e-02	1.00e+00	3.881	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	6.58e-02	1.00e+00	3.881	1	5	51
GO:0043066	negative regulation of apoptotic process	6.65e-02	1.00e+00	2.222	2	20	322
GO:0006368	transcription elongation from RNA polymerase II promoter	6.71e-02	1.00e+00	3.853	1	3	52
GO:0006289	nucleotide-excision repair	6.83e-02	1.00e+00	3.825	1	9	53
GO:0006338	chromatin remodeling	7.08e-02	1.00e+00	3.772	1	2	55
GO:0007565	female pregnancy	8.20e-02	1.00e+00	3.553	1	2	64
GO:0044822	poly(A) RNA binding	8.42e-02	1.00e+00	1.496	3	25	799
GO:0006364	rRNA processing	8.57e-02	1.00e+00	3.487	1	4	67
GO:0005200	structural constituent of cytoskeleton	8.69e-02	1.00e+00	3.466	1	2	68
GO:0051082	unfolded protein binding	8.93e-02	1.00e+00	3.424	1	4	70
GO:0001889	liver development	9.06e-02	1.00e+00	3.403	1	1	71
GO:0005815	microtubule organizing center	9.79e-02	1.00e+00	3.286	1	1	77
GO:0006915	apoptotic process	1.02e-01	1.00e+00	1.870	2	21	411
GO:0000086	G2/M transition of mitotic cell cycle	1.22e-01	1.00e+00	2.953	1	5	97
GO:0006457	protein folding	1.22e-01	1.00e+00	2.953	1	4	97
GO:0005515	protein binding	1.30e-01	1.00e+00	0.543	8	76	4124
GO:0007507	heart development	1.32e-01	1.00e+00	2.825	1	1	106
GO:0046777	protein autophosphorylation	1.32e-01	1.00e+00	2.825	1	2	106
GO:0000790	nuclear chromatin	1.36e-01	1.00e+00	2.785	1	3	109
GO:0006397	mRNA processing	1.37e-01	1.00e+00	2.772	1	2	110
GO:0016607	nuclear speck	1.51e-01	1.00e+00	2.622	1	3	122
GO:0004672	protein kinase activity	1.54e-01	1.00e+00	2.587	1	2	125
GO:0006351	transcription, DNA-templated	1.66e-01	1.00e+00	1.066	3	9	1076
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.73e-01	1.00e+00	2.403	1	2	142
GO:0005622	intracellular	1.77e-01	1.00e+00	2.373	1	1	145
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.222	1	4	161
GO:0007067	mitotic nuclear division	1.99e-01	1.00e+00	2.187	1	8	165
GO:0007283	spermatogenesis	2.02e-01	1.00e+00	2.161	1	2	168
GO:0043025	neuronal cell body	2.05e-01	1.00e+00	2.135	1	3	171
GO:0000166	nucleotide binding	2.11e-01	1.00e+00	2.094	1	6	176
GO:0005739	mitochondrion	2.17e-01	1.00e+00	1.189	2	11	659
GO:0005743	mitochondrial inner membrane	2.33e-01	1.00e+00	1.931	1	3	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.39e-01	1.00e+00	1.888	1	1	203
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	4	210
GO:0005813	centrosome	2.53e-01	1.00e+00	1.791	1	8	217
GO:0043231	intracellular membrane-bounded organelle	2.54e-01	1.00e+00	1.785	1	7	218
GO:0006200	ATP catabolic process	2.56e-01	1.00e+00	1.778	1	8	219
GO:0005737	cytoplasm	2.58e-01	1.00e+00	0.512	5	50	2633
GO:0045892	negative regulation of transcription, DNA-templated	3.49e-01	1.00e+00	1.245	1	7	317
GO:0006366	transcription from RNA polymerase II promoter	3.70e-01	1.00e+00	1.139	1	6	341
GO:0005794	Golgi apparatus	4.32e-01	1.00e+00	0.856	1	5	415
GO:0042803	protein homodimerization activity	4.42e-01	1.00e+00	0.811	1	5	428
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	7	452
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.88e-01	1.00e+00	0.222	1	8	644
GO:0008270	zinc ion binding	6.34e-01	1.00e+00	0.047	1	7	727
GO:0003677	DNA binding	7.35e-01	1.00e+00	-0.334	1	18	947

Wolf-ratios-Mammosphere-Adherent

reg-snw-6723

Statistics

Genes (13)

Interactions (22)

Related GO terms (194)