reg-snw-317781

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-317781 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
EIF6	3692	3	0.700	0.876	49	-	Yes	-
RBX1	9978	8	1.185	0.934	9	TF	Yes	-
PSMD3	5709	9	0.986	0.938	55	TF	Yes	-
PSMB7	5695	10	0.982	0.934	33	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
VARS	7407	7	0.549	0.938	124	TF	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
[ DDX51 ]	317781	1	0.059	0.823	180	TF	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot

Related GO terms (97)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.32e-08	3.24e-04	6.726	4	16	41
GO:0000502	proteasome complex	5.83e-08	5.69e-04	6.529	4	17	47
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.83e-08	8.63e-04	6.383	4	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9.55e-08	9.33e-04	6.356	4	17	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.20e-07	1.17e-03	6.276	4	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.29e-07	1.26e-03	6.251	4	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.59e-07	1.55e-03	6.177	4	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.70e-07	1.66e-03	6.153	4	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.20e-07	2.15e-03	6.061	4	17	65
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.97e-07	2.90e-03	5.954	4	16	70
GO:0000209	protein polyubiquitination	8.97e-07	8.76e-03	5.560	4	16	92
GO:0034641	cellular nitrogen compound metabolic process	1.53e-06	1.49e-02	5.369	4	18	105
GO:0042981	regulation of apoptotic process	1.98e-06	1.93e-02	5.276	4	18	112
GO:0000082	G1/S transition of mitotic cell cycle	3.07e-06	3.00e-02	5.118	4	24	125
GO:0000278	mitotic cell cycle	3.77e-06	3.69e-02	4.111	5	35	314
GO:0016071	mRNA metabolic process	1.04e-05	1.02e-01	4.674	4	21	170
GO:0016070	RNA metabolic process	1.55e-05	1.52e-01	4.529	4	21	188
GO:0016032	viral process	1.72e-05	1.68e-01	3.664	5	32	428
GO:0005838	proteasome regulatory particle	3.39e-05	3.31e-01	7.762	2	4	10
GO:0010467	gene expression	5.08e-05	4.96e-01	3.342	5	31	535
GO:0022624	proteasome accessory complex	6.83e-05	6.67e-01	7.276	2	7	14
GO:0005839	proteasome core complex	9.00e-05	8.79e-01	7.083	2	9	16
GO:0004298	threonine-type endopeptidase activity	1.02e-04	9.96e-01	6.996	2	9	17
GO:0043066	negative regulation of apoptotic process	1.28e-04	1.00e+00	3.753	4	20	322
GO:0005829	cytosol	1.73e-04	1.00e+00	2.088	7	58	1787
GO:0006915	apoptotic process	3.29e-04	1.00e+00	3.400	4	21	411
GO:0005654	nucleoplasm	5.32e-04	1.00e+00	2.631	5	55	876
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0000054	ribosomal subunit export from nucleus	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0030891	VCB complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0031467	Cul7-RING ubiquitin ligase complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005730	nucleolus	2.44e-03	1.00e+00	2.156	5	41	1217
GO:0042256	mature ribosome assembly	2.76e-03	1.00e+00	8.499	1	1	3
GO:0005638	lamin filament	2.76e-03	1.00e+00	8.499	1	1	3
GO:0019788	NEDD8 ligase activity	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0031461	cullin-RING ubiquitin ligase complex	3.68e-03	1.00e+00	8.083	1	2	4
GO:0043248	proteasome assembly	3.68e-03	1.00e+00	8.083	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	4.60e-03	1.00e+00	7.762	1	2	5
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0043023	ribosomal large subunit binding	4.60e-03	1.00e+00	7.762	1	2	5
GO:0044281	small molecule metabolic process	4.90e-03	1.00e+00	2.362	4	32	844
GO:0031462	Cul2-RING ubiquitin ligase complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0045116	protein neddylation	6.44e-03	1.00e+00	7.276	1	1	7
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0070062	extracellular vesicular exosome	9.25e-03	1.00e+00	1.725	5	43	1641
GO:0042273	ribosomal large subunit biogenesis	1.01e-02	1.00e+00	6.624	1	3	11
GO:0030234	enzyme regulator activity	1.01e-02	1.00e+00	6.624	1	2	11
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0048863	stem cell differentiation	1.10e-02	1.00e+00	6.499	1	1	12
GO:0010243	response to organonitrogen compound	1.28e-02	1.00e+00	6.276	1	1	14
GO:0042176	regulation of protein catabolic process	1.28e-02	1.00e+00	6.276	1	2	14
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1.47e-02	1.00e+00	6.083	1	1	16
GO:0031463	Cul3-RING ubiquitin ligase complex	1.47e-02	1.00e+00	6.083	1	1	16
GO:0006513	protein monoubiquitination	1.56e-02	1.00e+00	5.996	1	1	17
GO:0043022	ribosome binding	1.56e-02	1.00e+00	5.996	1	1	17
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0016020	membrane	1.75e-02	1.00e+00	1.846	4	38	1207
GO:0019005	SCF ubiquitin ligase complex	1.83e-02	1.00e+00	5.762	1	1	20
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.01e-02	1.00e+00	5.624	1	1	22
GO:0008026	ATP-dependent helicase activity	2.64e-02	1.00e+00	5.225	1	1	29
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	1	29
GO:0014070	response to organic cyclic compound	3.09e-02	1.00e+00	4.996	1	1	34
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	2	37
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	5.05e-02	1.00e+00	4.276	1	3	56
GO:0006364	rRNA processing	6.01e-02	1.00e+00	4.017	1	4	67
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0071456	cellular response to hypoxia	6.79e-02	1.00e+00	3.836	1	2	76
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	2	92
GO:0007219	Notch signaling pathway	8.43e-02	1.00e+00	3.514	1	4	95
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0006413	translational initiation	8.77e-02	1.00e+00	3.454	1	4	99
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	3	119
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	3	130
GO:0032403	protein complex binding	1.14e-01	1.00e+00	3.061	1	2	130
GO:0031625	ubiquitin protein ligase binding	1.20e-01	1.00e+00	2.975	1	5	138
GO:0005515	protein binding	1.26e-01	1.00e+00	0.659	6	76	4124
GO:0005634	nucleus	1.43e-01	1.00e+00	0.741	5	67	3246
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	2	179
GO:0016567	protein ubiquitination	1.61e-01	1.00e+00	2.529	1	3	188
GO:0005525	GTP binding	1.68e-01	1.00e+00	2.461	1	5	197
GO:0006281	DNA repair	1.72e-01	1.00e+00	2.418	1	19	203
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.309	1	8	219
GO:0005524	ATP binding	1.96e-01	1.00e+00	1.283	2	23	892
GO:0005737	cytoplasm	4.54e-01	1.00e+00	0.306	3	50	2633
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	11	659
GO:0008270	zinc ion binding	5.02e-01	1.00e+00	0.578	1	7	727
GO:0044822	poly(A) RNA binding	5.36e-01	1.00e+00	0.441	1	25	799

Wolf-ratios-Mammosphere-Adherent

reg-snw-317781

Statistics

Genes (9)

Interactions (11)

Related GO terms (97)