reg-snw-84320

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.274 1.19e-07 2.93e-02 2.28e-02
chia-screen-data-Fav-reg-snw-84320 subnetwork

Genes (23)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
TMEM68 137695 6-1.5652.31297TF--
AGPS 8540 23-2.4242.41027-YesYes
PHB 5245 82-2.7432.68936-YesYes
[ ACBD6 ] 84320 1-1.2442.27429TF--
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
MCTS1 28985 2-1.3802.41019---
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
SYNCRIP 10492 42-2.4012.503144TFYesYes
SUV39H2 79723 27-2.3072.41021-YesYes
ALKBH8 91801 8-2.1472.4105-Yes-
FTSJ1 24140 43-2.4632.68935-YesYes
EIF2S1 1965 5-1.8012.41063TF--
ETF1 2107 35-2.8292.5036-YesYes
GSPT1 2935 32-2.3132.50317-YesYes
CCT7 10574 40-2.3352.45938-Yes-
CPSF3 51692 43-2.6862.50331-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
NOLC1 9221 15-1.9852.503113TF--
POLH 5429 36-2.5862.45924-YesYes
FAM78B 149297 1-1.3882.27413---

Interactions (29)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
EIF2S1 1965 ETF1 2107 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
NOLC1 9221 FAM78B 149297 pd > reg.ITFP.txt: no annot
ACBD6 84320 FAM78B 149297 pd > reg.ITFP.txt: no annot
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 MCTS1 28985 pd > reg.ITFP.txt: no annot
CPSF3 51692 TMEM68 137695 pd < reg.ITFP.txt: no annot
MCTS1 28985 ACBD6 84320 pd < reg.ITFP.txt: no annot
EIF2S1 1965 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
AGPS 8540 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 ALKBH8 91801 pd > reg.ITFP.txt: no annot
TMEM68 137695 FAM78B 149297 pd > reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
EIF2S1 1965 MCTS1 28985 pd > reg.ITFP.txt: no annot
FBXO22 26263 MCTS1 28985 pd > reg.ITFP.txt: no annot
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 CPSF3 51692 pd > reg.ITFP.txt: no annot
SUV39H2 79723 TMEM68 137695 pd < reg.ITFP.txt: no annot

Related GO terms (199)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0003747translation release factor activity5.31e-065.18e-028.730222
GO:0005850eukaryotic translation initiation factor 2 complex1.59e-051.55e-018.145223
GO:0003743translation initiation factor activity8.42e-058.22e-015.1053837
GO:0006379mRNA cleavage1.89e-041.00e+006.560229
GO:0003723RNA binding2.30e-041.00e+003.103522247
GO:0006479protein methylation2.88e-041.00e+006.2702211
GO:0043022ribosome binding7.06e-041.00e+005.6422217
GO:0030529ribonucleoprotein complex8.95e-041.00e+003.9573582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay9.60e-041.00e+003.9223584
GO:0010467gene expression1.19e-031.00e+002.251649535
GO:0044822poly(A) RNA binding1.83e-031.00e+001.895745799
GO:0004832valine-tRNA ligase activity2.36e-031.00e+008.730111
GO:0016149translation release factor activity, codon specific2.36e-031.00e+008.730111
GO:0002128tRNA nucleoside ribose methylation2.36e-031.00e+008.730111
GO:0016300tRNA (uracil) methyltransferase activity2.36e-031.00e+008.730111
GO:0008175tRNA methyltransferase activity2.36e-031.00e+008.730111
GO:0008609alkylglycerone-phosphate synthase activity2.36e-031.00e+008.730111
GO:0008079translation termination factor activity2.36e-031.00e+008.730111
GO:0006438valyl-tRNA aminoacylation2.36e-031.00e+008.730111
GO:0007049cell cycle2.37e-031.00e+003.46938115
GO:0031124mRNA 3'-end processing3.01e-031.00e+004.6012435
GO:0000398mRNA splicing, via spliceosome3.22e-031.00e+003.315315128
GO:0006369termination of RNA polymerase II transcription3.54e-031.00e+004.4822538
GO:0048742regulation of skeletal muscle fiber development4.71e-031.00e+007.730112
GO:0043558regulation of translational initiation in response to stress4.71e-031.00e+007.730112
GO:0005846nuclear cap binding complex4.71e-031.00e+007.730112
GO:0002176male germ cell proliferation4.71e-031.00e+007.730112
GO:0008611ether lipid biosynthetic process4.71e-031.00e+007.730112
GO:0006406mRNA export from nucleus4.73e-031.00e+004.2702744
GO:0008380RNA splicing6.54e-031.00e+002.948321165
GO:0008762UDP-N-acetylmuramate dehydrogenase activity7.05e-031.00e+007.145113
GO:0036123histone H3-K9 dimethylation7.05e-031.00e+007.145113
GO:0002098tRNA wobble uridine modification7.05e-031.00e+007.145113
GO:0002192IRES-dependent translational initiation7.05e-031.00e+007.145123
GO:0006412translation8.07e-031.00e+002.839312178
GO:0044267cellular protein metabolic process8.54e-031.00e+002.270414352
GO:0045292mRNA cis splicing, via spliceosome9.39e-031.00e+006.730114
GO:0097452GAIT complex9.39e-031.00e+006.730124
GO:0031442positive regulation of mRNA 3'-end processing9.39e-031.00e+006.730114
GO:0006290pyrimidine dimer repair9.39e-031.00e+006.730124
GO:0006449regulation of translational termination9.39e-031.00e+006.730114
GO:0007000nucleolus organization9.39e-031.00e+006.730114
GO:0006333chromatin assembly or disassembly9.39e-031.00e+006.730114
GO:0036124histone H3-K9 trimethylation9.39e-031.00e+006.730124
GO:0005851eukaryotic translation initiation factor 2B complex9.39e-031.00e+006.730124
GO:0006415translational termination9.50e-031.00e+003.7532263
GO:0004521endoribonuclease activity1.17e-021.00e+006.408115
GO:0008610lipid biosynthetic process1.17e-021.00e+006.408115
GO:0006398histone mRNA 3'-end processing1.17e-021.00e+006.408115
GO:0032790ribosome disassembly1.17e-021.00e+006.408125
GO:0070934CRD-mediated mRNA stabilization1.17e-021.00e+006.408125
GO:0006282regulation of DNA repair1.17e-021.00e+006.408125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.17e-021.00e+006.408115
GO:0002161aminoacyl-tRNA editing activity1.17e-021.00e+006.408115
GO:0071204histone pre-mRNA 3'end processing complex1.17e-021.00e+006.408115
GO:0001649osteoblast differentiation1.29e-021.00e+003.5202574
GO:0050847progesterone receptor signaling pathway1.41e-021.00e+006.145126
GO:0002181cytoplasmic translation1.41e-021.00e+006.145116
GO:0042754negative regulation of circadian rhythm1.41e-021.00e+006.145126
GO:0046974histone methyltransferase activity (H3-K9 specific)1.41e-021.00e+006.145116
GO:0070937CRD-mediated mRNA stability complex1.41e-021.00e+006.145126
GO:0002199zona pellucida receptor complex1.64e-021.00e+005.922147
GO:0007140male meiosis1.64e-021.00e+005.922117
GO:0000731DNA synthesis involved in DNA repair1.64e-021.00e+005.922117
GO:0006301postreplication repair1.64e-021.00e+005.922127
GO:0000062fatty-acyl-CoA binding1.64e-021.00e+005.922117
GO:00084095'-3' exonuclease activity1.64e-021.00e+005.922127
GO:0000339RNA cap binding1.64e-021.00e+005.922117
GO:0005832chaperonin-containing T-complex1.64e-021.00e+005.922147
GO:0005739mitochondrion1.68e-021.00e+001.688532659
GO:0005845mRNA cap binding complex1.87e-021.00e+005.730118
GO:0006450regulation of translational fidelity1.87e-021.00e+005.730118
GO:0016706oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors1.87e-021.00e+005.730118
GO:0010944negative regulation of transcription by competitive promoter binding1.87e-021.00e+005.730118
GO:0071949FAD binding1.87e-021.00e+005.730118
GO:0010388cullin deneddylation1.87e-021.00e+005.730148
GO:0010225response to UV-C2.10e-021.00e+005.560129
GO:0030488tRNA methylation2.10e-021.00e+005.560129
GO:0071354cellular response to interleukin-62.10e-021.00e+005.560119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.10e-021.00e+005.560129
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.10e-021.00e+005.560139
GO:0006413translational initiation2.24e-021.00e+003.1002699
GO:0005095GTPase inhibitor activity2.33e-021.00e+005.4081110
GO:0008143poly(A) binding2.33e-021.00e+005.4081210
GO:0060766negative regulation of androgen receptor signaling pathway2.56e-021.00e+005.2701411
GO:0008334histone mRNA metabolic process2.56e-021.00e+005.2701111
GO:0006974cellular response to DNA damage stimulus3.25e-021.00e+002.811211121
GO:0001731formation of translation preinitiation complex3.25e-021.00e+004.9221314
GO:0016746transferase activity, transferring acyl groups3.25e-021.00e+004.9221214
GO:0016575histone deacetylation3.25e-021.00e+004.9221214
GO:0008135translation factor activity, nucleic acid binding3.48e-021.00e+004.8231415
GO:0000188inactivation of MAPK activity3.48e-021.00e+004.8231115
GO:0007339binding of sperm to zona pellucida3.48e-021.00e+004.8231415
GO:0003887DNA-directed DNA polymerase activity3.71e-021.00e+004.7301216
GO:0005782peroxisomal matrix3.71e-021.00e+004.7301116
GO:0031047gene silencing by RNA4.16e-021.00e+004.5601218
GO:0006378mRNA polyadenylation4.16e-021.00e+004.5601318
GO:0005844polysome4.39e-021.00e+004.4821219
GO:0006913nucleocytoplasmic transport4.61e-021.00e+004.4081220
GO:0071346cellular response to interferon-gamma4.61e-021.00e+004.4081220
GO:0005720nuclear heterochromatin4.61e-021.00e+004.4081320
GO:0071897DNA biosynthetic process4.61e-021.00e+004.4081220
GO:0034660ncRNA metabolic process4.61e-021.00e+004.4081120
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic4.84e-021.00e+004.3381221
GO:0005654nucleoplasm4.96e-021.00e+001.277568876
GO:0051084'de novo' posttranslational protein folding5.06e-021.00e+004.2701422
GO:0000387spliceosomal snRNP assembly5.06e-021.00e+004.2701122
GO:0000049tRNA binding5.29e-021.00e+004.2061223
GO:00063707-methylguanosine mRNA capping5.51e-021.00e+004.1451524
GO:0008180COP9 signalosome5.51e-021.00e+004.1451624
GO:0005515protein binding5.56e-021.00e+000.527141984124
GO:0000976transcription regulatory region sequence-specific DNA binding5.73e-021.00e+004.0861325
GO:0009267cellular response to starvation5.95e-021.00e+004.0291126
GO:0010494cytoplasmic stress granule5.95e-021.00e+004.0291426
GO:0016071mRNA metabolic process6.00e-021.00e+002.320210170
GO:0006418tRNA aminoacylation for protein translation6.62e-021.00e+003.8721429
GO:0005778peroxisomal membrane6.62e-021.00e+003.8721329
GO:0006446regulation of translational initiation6.62e-021.00e+003.8721229
GO:0022627cytosolic small ribosomal subunit6.84e-021.00e+003.8231130
GO:0016070RNA metabolic process7.16e-021.00e+002.175210188
GO:0015030Cajal body7.28e-021.00e+003.7301332
GO:0017148negative regulation of translation7.50e-021.00e+003.6851533
GO:0007254JNK cascade7.72e-021.00e+003.6421134
GO:0005525GTP binding7.77e-021.00e+002.108212197
GO:0050434positive regulation of viral transcription7.94e-021.00e+003.6011535
GO:0044297cell body7.94e-021.00e+003.6011535
GO:0040008regulation of growth8.37e-021.00e+003.5201137
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process8.59e-021.00e+003.4821438
GO:0048511rhythmic process8.59e-021.00e+003.4821538
GO:0006396RNA processing9.02e-021.00e+003.4081440
GO:0000775chromosome, centromeric region9.23e-021.00e+003.3721641
GO:0003684damaged DNA binding9.23e-021.00e+003.3721141
GO:0006987activation of signaling protein activity involved in unfolded protein response1.05e-011.00e+003.1751147
GO:0005777peroxisome1.11e-011.00e+003.0861250
GO:0005829cytosol1.12e-011.00e+000.7347881787
GO:0006368transcription elongation from RNA polymerase II promoter1.16e-011.00e+003.0291852
GO:0006338chromatin remodeling1.22e-011.00e+002.9481755
GO:0008584male gonad development1.26e-011.00e+002.8971157
GO:0042826histone deacetylase binding1.28e-011.00e+002.8721558
GO:0000785chromatin1.30e-011.00e+002.8471659
GO:0071013catalytic step 2 spliceosome1.34e-011.00e+002.7991561
GO:0006464cellular protein modification process1.34e-011.00e+002.7991461
GO:0030968endoplasmic reticulum unfolded protein response1.34e-011.00e+002.7991161
GO:0005737cytoplasm1.40e-011.00e+000.53791272633
GO:0030018Z disc1.41e-011.00e+002.7301364
GO:0006364rRNA processing1.47e-011.00e+002.6641267
GO:0030308negative regulation of cell growth1.53e-011.00e+002.6011370
GO:0051082unfolded protein binding1.53e-011.00e+002.6011570
GO:0008289lipid binding1.59e-011.00e+002.5401473
GO:0055114oxidation-reduction process1.63e-011.00e+001.46329308
GO:0071456cellular response to hypoxia1.65e-011.00e+002.4821276
GO:0045892negative regulation of transcription, DNA-templated1.71e-011.00e+001.422217317
GO:0044255cellular lipid metabolic process1.90e-011.00e+002.2541289
GO:0006366transcription from RNA polymerase II promoter1.91e-011.00e+001.316223341
GO:0005506iron ion binding1.96e-011.00e+002.2061492
GO:0000209protein polyubiquitination1.96e-011.00e+002.2061692
GO:0006511ubiquitin-dependent protein catabolic process1.96e-011.00e+002.2061692
GO:0006260DNA replication2.00e-011.00e+002.1751994
GO:0006457protein folding2.05e-011.00e+002.1301597
GO:0046777protein autophosphorylation2.22e-011.00e+002.00213106
GO:0042981regulation of apoptotic process2.33e-011.00e+001.92214112
GO:0003924GTPase activity2.46e-011.00e+001.83517119
GO:0000082G1/S transition of mitotic cell cycle2.57e-011.00e+001.76414125
GO:0006184GTP catabolic process2.66e-011.00e+001.70717130
GO:0016032viral process2.67e-011.00e+000.988230428
GO:0044212transcription regulatory region DNA binding2.88e-011.00e+001.570113143
GO:0005622intracellular2.91e-011.00e+001.55012145
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.92e-011.00e+000.897229456
GO:0001701in utero embryonic development3.07e-011.00e+001.46317154
GO:0016020membrane3.15e-011.00e+000.4934561207
GO:0005874microtubule3.21e-011.00e+001.381110163
GO:0007067mitotic nuclear division3.25e-011.00e+001.36419165
GO:0000166nucleotide binding3.42e-011.00e+001.270113176
GO:0004842ubiquitin-protein transferase activity3.47e-011.00e+001.246117179
GO:0008152metabolic process3.52e-011.00e+001.22216182
GO:0005524ATP binding3.52e-011.00e+000.514337892
GO:0005743mitochondrial inner membrane3.75e-011.00e+001.10819197
GO:0046872metal ion binding3.80e-011.00e+000.448324934
GO:0006281DNA repair3.84e-011.00e+001.065124203
GO:0030154cell differentiation3.85e-011.00e+001.05715204
GO:0019899enzyme binding3.94e-011.00e+001.01617210
GO:0043231intracellular membrane-bounded organelle4.05e-011.00e+000.96218218
GO:0003682chromatin binding4.52e-011.00e+000.753115252
GO:0008285negative regulation of cell proliferation4.85e-011.00e+000.616111277
GO:0008284positive regulation of cell proliferation4.87e-011.00e+000.60618279
GO:0006355regulation of transcription, DNA-templated5.10e-011.00e+000.248231715
GO:0008270zinc ion binding5.19e-011.00e+000.224239727
GO:0005730nucleolus5.60e-011.00e+000.0663741217
GO:0042802identical protein binding5.73e-011.00e+000.262115354
GO:0045893positive regulation of transcription, DNA-templated5.96e-011.00e+000.171121377
GO:0005783endoplasmic reticulum6.00e-011.00e+000.156112381
GO:0005634nucleus6.87e-011.00e+00-0.12771583246
GO:0006351transcription, DNA-templated7.38e-011.00e+00-0.3422471076
GO:0005887integral component of plasma membrane7.53e-011.00e+00-0.43818575
GO:0070062extracellular vesicular exosome7.68e-011.00e+00-0.3663511641
GO:0007165signal transduction7.78e-011.00e+00-0.542124618
GO:0044281small molecule metabolic process8.75e-011.00e+00-0.991135844
GO:0005886plasma membrane9.41e-011.00e+00-1.0712461784
GO:0016021integral component of membrane9.80e-011.00e+00-1.8461191526