reg-snw-28985

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.410	2.13e-08	1.11e-02	9.52e-03

chia-screen-data-Fav-reg-snw-28985 subnetwork

Genes (19)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
FBXO22	26263	36	-1.739	2.459	208	TF	-	-
[ MCTS1 ]	28985	2	-1.380	2.410	19	-	-	-
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
ALKBH8	91801	8	-2.147	2.410	5	-	Yes	-
EIF2S1	1965	5	-1.801	2.410	63	TF	-	-
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes

Interactions (21)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EIF2S1	1965	ETF1	2107	pd	>	reg.ITFP.txt: no annot
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	MCTS1	28985	pd	>	reg.ITFP.txt: no annot
EIF2S1	1965	MCTS1	28985	pd	>	reg.ITFP.txt: no annot
FBXO22	26263	MCTS1	28985	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
EIF2S1	1965	SYNCRIP	10492	pd	<>	reg.ITFP.txt: no annot
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	ALKBH8	91801	pd	>	reg.ITFP.txt: no annot

Related GO terms (191)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	3.59e-06	3.50e-02	9.005	2	2	2
GO:0005850	eukaryotic translation initiation factor 2 complex	1.07e-05	1.05e-01	8.421	2	2	3
GO:0003743	translation initiation factor activity	4.65e-05	4.54e-01	5.381	3	8	37
GO:0003723	RNA binding	8.65e-05	8.44e-01	3.379	5	22	247
GO:0006379	mRNA cleavage	1.28e-04	1.00e+00	6.836	2	2	9
GO:0006479	protein methylation	1.95e-04	1.00e+00	6.546	2	2	11
GO:0010467	gene expression	3.86e-04	1.00e+00	2.527	6	49	535
GO:0043022	ribosome binding	4.79e-04	1.00e+00	5.918	2	2	17
GO:0030529	ribonucleoprotein complex	5.02e-04	1.00e+00	4.233	3	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.39e-04	1.00e+00	4.198	3	5	84
GO:0000398	mRNA splicing, via spliceosome	1.83e-03	1.00e+00	3.590	3	15	128
GO:0004832	valine-tRNA ligase activity	1.95e-03	1.00e+00	9.005	1	1	1
GO:0016149	translation release factor activity, codon specific	1.95e-03	1.00e+00	9.005	1	1	1
GO:0016300	tRNA (uracil) methyltransferase activity	1.95e-03	1.00e+00	9.005	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	1.95e-03	1.00e+00	9.005	1	1	1
GO:0008079	translation termination factor activity	1.95e-03	1.00e+00	9.005	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.95e-03	1.00e+00	9.005	1	1	1
GO:0031124	mRNA 3'-end processing	2.05e-03	1.00e+00	4.876	2	4	35
GO:0006369	termination of RNA polymerase II transcription	2.42e-03	1.00e+00	4.758	2	5	38
GO:0000775	chromosome, centromeric region	2.81e-03	1.00e+00	4.648	2	6	41
GO:0044822	poly(A) RNA binding	3.16e-03	1.00e+00	1.948	6	45	799
GO:0006406	mRNA export from nucleus	3.23e-03	1.00e+00	4.546	2	7	44
GO:0008380	RNA splicing	3.76e-03	1.00e+00	3.224	3	21	165
GO:0048742	regulation of skeletal muscle fiber development	3.89e-03	1.00e+00	8.005	1	1	2
GO:0043558	regulation of translational initiation in response to stress	3.89e-03	1.00e+00	8.005	1	1	2
GO:0005846	nuclear cap binding complex	3.89e-03	1.00e+00	8.005	1	1	2
GO:0002176	male germ cell proliferation	3.89e-03	1.00e+00	8.005	1	1	2
GO:0008611	ether lipid biosynthetic process	3.89e-03	1.00e+00	8.005	1	1	2
GO:0044267	cellular protein metabolic process	4.19e-03	1.00e+00	2.546	4	14	352
GO:0006412	translation	4.65e-03	1.00e+00	3.115	3	12	178
GO:0005654	nucleoplasm	5.01e-03	1.00e+00	1.816	6	68	876
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	5.83e-03	1.00e+00	7.421	1	1	3
GO:0036123	histone H3-K9 dimethylation	5.83e-03	1.00e+00	7.421	1	1	3
GO:0002098	tRNA wobble uridine modification	5.83e-03	1.00e+00	7.421	1	1	3
GO:0002192	IRES-dependent translational initiation	5.83e-03	1.00e+00	7.421	1	2	3
GO:0006415	translational termination	6.53e-03	1.00e+00	4.028	2	2	63
GO:0005739	mitochondrion	7.24e-03	1.00e+00	1.963	5	32	659
GO:0045292	mRNA cis splicing, via spliceosome	7.76e-03	1.00e+00	7.005	1	1	4
GO:0097452	GAIT complex	7.76e-03	1.00e+00	7.005	1	2	4
GO:0031442	positive regulation of mRNA 3'-end processing	7.76e-03	1.00e+00	7.005	1	1	4
GO:0006290	pyrimidine dimer repair	7.76e-03	1.00e+00	7.005	1	2	4
GO:0006449	regulation of translational termination	7.76e-03	1.00e+00	7.005	1	1	4
GO:0036124	histone H3-K9 trimethylation	7.76e-03	1.00e+00	7.005	1	2	4
GO:0006333	chromatin assembly or disassembly	7.76e-03	1.00e+00	7.005	1	1	4
GO:0005851	eukaryotic translation initiation factor 2B complex	7.76e-03	1.00e+00	7.005	1	2	4
GO:0001649	osteoblast differentiation	8.91e-03	1.00e+00	3.796	2	5	74
GO:0004521	endoribonuclease activity	9.69e-03	1.00e+00	6.684	1	1	5
GO:0008610	lipid biosynthetic process	9.69e-03	1.00e+00	6.684	1	1	5
GO:0006398	histone mRNA 3'-end processing	9.69e-03	1.00e+00	6.684	1	1	5
GO:0032790	ribosome disassembly	9.69e-03	1.00e+00	6.684	1	2	5
GO:0070934	CRD-mediated mRNA stabilization	9.69e-03	1.00e+00	6.684	1	2	5
GO:0006282	regulation of DNA repair	9.69e-03	1.00e+00	6.684	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	9.69e-03	1.00e+00	6.684	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	9.69e-03	1.00e+00	6.684	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	9.69e-03	1.00e+00	6.684	1	1	5
GO:0050847	progesterone receptor signaling pathway	1.16e-02	1.00e+00	6.421	1	2	6
GO:0042754	negative regulation of circadian rhythm	1.16e-02	1.00e+00	6.421	1	2	6
GO:0046974	histone methyltransferase activity (H3-K9 specific)	1.16e-02	1.00e+00	6.421	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	1.16e-02	1.00e+00	6.421	1	2	6
GO:0002199	zona pellucida receptor complex	1.35e-02	1.00e+00	6.198	1	4	7
GO:0007140	male meiosis	1.35e-02	1.00e+00	6.198	1	1	7
GO:0000731	DNA synthesis involved in DNA repair	1.35e-02	1.00e+00	6.198	1	1	7
GO:0006301	postreplication repair	1.35e-02	1.00e+00	6.198	1	2	7
GO:0008409	5'-3' exonuclease activity	1.35e-02	1.00e+00	6.198	1	2	7
GO:0000339	RNA cap binding	1.35e-02	1.00e+00	6.198	1	1	7
GO:0005832	chaperonin-containing T-complex	1.35e-02	1.00e+00	6.198	1	4	7
GO:0005829	cytosol	1.38e-02	1.00e+00	1.202	8	88	1787
GO:0005845	mRNA cap binding complex	1.55e-02	1.00e+00	6.005	1	1	8
GO:0006450	regulation of translational fidelity	1.55e-02	1.00e+00	6.005	1	1	8
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.55e-02	1.00e+00	6.005	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.55e-02	1.00e+00	6.005	1	1	8
GO:0071949	FAD binding	1.55e-02	1.00e+00	6.005	1	1	8
GO:0010388	cullin deneddylation	1.55e-02	1.00e+00	6.005	1	4	8
GO:0006413	translational initiation	1.56e-02	1.00e+00	3.376	2	6	99
GO:0010225	response to UV-C	1.74e-02	1.00e+00	5.836	1	2	9
GO:0030488	tRNA methylation	1.74e-02	1.00e+00	5.836	1	2	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.74e-02	1.00e+00	5.836	1	2	9
GO:0071354	cellular response to interleukin-6	1.74e-02	1.00e+00	5.836	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.74e-02	1.00e+00	5.836	1	3	9
GO:0005515	protein binding	1.92e-02	1.00e+00	0.696	13	198	4124
GO:0005095	GTPase inhibitor activity	1.93e-02	1.00e+00	5.684	1	1	10
GO:0008143	poly(A) binding	1.93e-02	1.00e+00	5.684	1	2	10
GO:0007049	cell cycle	2.06e-02	1.00e+00	3.160	2	8	115
GO:0060766	negative regulation of androgen receptor signaling pathway	2.12e-02	1.00e+00	5.546	1	4	11
GO:0008334	histone mRNA metabolic process	2.12e-02	1.00e+00	5.546	1	1	11
GO:0006974	cellular response to DNA damage stimulus	2.27e-02	1.00e+00	3.087	2	11	121
GO:0001731	formation of translation preinitiation complex	2.69e-02	1.00e+00	5.198	1	3	14
GO:0016575	histone deacetylation	2.69e-02	1.00e+00	5.198	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	2.88e-02	1.00e+00	5.099	1	4	15
GO:0000188	inactivation of MAPK activity	2.88e-02	1.00e+00	5.099	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.88e-02	1.00e+00	5.099	1	4	15
GO:0003887	DNA-directed DNA polymerase activity	3.07e-02	1.00e+00	5.005	1	2	16
GO:0005782	peroxisomal matrix	3.07e-02	1.00e+00	5.005	1	1	16
GO:0031047	gene silencing by RNA	3.45e-02	1.00e+00	4.836	1	2	18
GO:0006378	mRNA polyadenylation	3.45e-02	1.00e+00	4.836	1	3	18
GO:0005844	polysome	3.64e-02	1.00e+00	4.758	1	2	19
GO:0006913	nucleocytoplasmic transport	3.82e-02	1.00e+00	4.684	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	3.82e-02	1.00e+00	4.684	1	2	20
GO:0071346	cellular response to interferon-gamma	3.82e-02	1.00e+00	4.684	1	2	20
GO:0005720	nuclear heterochromatin	3.82e-02	1.00e+00	4.684	1	3	20
GO:0071897	DNA biosynthetic process	3.82e-02	1.00e+00	4.684	1	2	20
GO:0034660	ncRNA metabolic process	3.82e-02	1.00e+00	4.684	1	1	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	4.01e-02	1.00e+00	4.613	1	2	21
GO:0051084	'de novo' posttranslational protein folding	4.20e-02	1.00e+00	4.546	1	4	22
GO:0000387	spliceosomal snRNP assembly	4.20e-02	1.00e+00	4.546	1	1	22
GO:0016071	mRNA metabolic process	4.24e-02	1.00e+00	2.596	2	10	170
GO:0000049	tRNA binding	4.39e-02	1.00e+00	4.482	1	2	23
GO:0006370	7-methylguanosine mRNA capping	4.57e-02	1.00e+00	4.421	1	5	24
GO:0008180	COP9 signalosome	4.57e-02	1.00e+00	4.421	1	6	24
GO:0000976	transcription regulatory region sequence-specific DNA binding	4.76e-02	1.00e+00	4.362	1	3	25
GO:0009267	cellular response to starvation	4.94e-02	1.00e+00	4.305	1	1	26
GO:0010494	cytoplasmic stress granule	4.94e-02	1.00e+00	4.305	1	4	26
GO:0016070	RNA metabolic process	5.09e-02	1.00e+00	2.451	2	10	188
GO:0006418	tRNA aminoacylation for protein translation	5.50e-02	1.00e+00	4.147	1	4	29
GO:0005778	peroxisomal membrane	5.50e-02	1.00e+00	4.147	1	3	29
GO:0006446	regulation of translational initiation	5.50e-02	1.00e+00	4.147	1	2	29
GO:0022627	cytosolic small ribosomal subunit	5.68e-02	1.00e+00	4.099	1	1	30
GO:0045111	intermediate filament cytoskeleton	5.87e-02	1.00e+00	4.051	1	3	31
GO:0017148	negative regulation of translation	6.23e-02	1.00e+00	3.961	1	5	33
GO:0007254	JNK cascade	6.42e-02	1.00e+00	3.918	1	1	34
GO:0050434	positive regulation of viral transcription	6.60e-02	1.00e+00	3.876	1	5	35
GO:0044297	cell body	6.60e-02	1.00e+00	3.876	1	5	35
GO:0040008	regulation of growth	6.97e-02	1.00e+00	3.796	1	1	37
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	7.15e-02	1.00e+00	3.758	1	4	38
GO:0048511	rhythmic process	7.15e-02	1.00e+00	3.758	1	5	38
GO:0006396	RNA processing	7.51e-02	1.00e+00	3.684	1	4	40
GO:0003684	damaged DNA binding	7.69e-02	1.00e+00	3.648	1	1	41
GO:0006987	activation of signaling protein activity involved in unfolded protein response	8.77e-02	1.00e+00	3.451	1	1	47
GO:0005777	peroxisome	9.30e-02	1.00e+00	3.362	1	2	50
GO:0006334	nucleosome assembly	9.48e-02	1.00e+00	3.333	1	4	51
GO:0006368	transcription elongation from RNA polymerase II promoter	9.66e-02	1.00e+00	3.305	1	8	52
GO:0006338	chromatin remodeling	1.02e-01	1.00e+00	3.224	1	7	55
GO:0008584	male gonad development	1.05e-01	1.00e+00	3.173	1	1	57
GO:0042826	histone deacetylase binding	1.07e-01	1.00e+00	3.147	1	5	58
GO:0000785	chromatin	1.09e-01	1.00e+00	3.123	1	6	59
GO:0071013	catalytic step 2 spliceosome	1.12e-01	1.00e+00	3.075	1	5	61
GO:0006464	cellular protein modification process	1.12e-01	1.00e+00	3.075	1	4	61
GO:0030968	endoplasmic reticulum unfolded protein response	1.12e-01	1.00e+00	3.075	1	1	61
GO:0030018	Z disc	1.18e-01	1.00e+00	3.005	1	3	64
GO:0055114	oxidation-reduction process	1.19e-01	1.00e+00	1.739	2	9	308
GO:0045892	negative regulation of transcription, DNA-templated	1.25e-01	1.00e+00	1.697	2	17	317
GO:0030308	negative regulation of cell growth	1.28e-01	1.00e+00	2.876	1	3	70
GO:0051082	unfolded protein binding	1.28e-01	1.00e+00	2.876	1	5	70
GO:0071456	cellular response to hypoxia	1.38e-01	1.00e+00	2.758	1	2	76
GO:0006366	transcription from RNA polymerase II promoter	1.41e-01	1.00e+00	1.592	2	23	341
GO:0044255	cellular lipid metabolic process	1.60e-01	1.00e+00	2.530	1	2	89
GO:0005506	iron ion binding	1.65e-01	1.00e+00	2.482	1	4	92
GO:0000209	protein polyubiquitination	1.65e-01	1.00e+00	2.482	1	6	92
GO:0006511	ubiquitin-dependent protein catabolic process	1.65e-01	1.00e+00	2.482	1	6	92
GO:0006260	DNA replication	1.68e-01	1.00e+00	2.451	1	9	94
GO:0006457	protein folding	1.73e-01	1.00e+00	2.406	1	5	97
GO:0046777	protein autophosphorylation	1.87e-01	1.00e+00	2.278	1	3	106
GO:0042981	regulation of apoptotic process	1.97e-01	1.00e+00	2.198	1	4	112
GO:0016020	membrane	2.01e-01	1.00e+00	0.768	4	56	1207
GO:0016032	viral process	2.02e-01	1.00e+00	1.264	2	30	428
GO:0003924	GTPase activity	2.08e-01	1.00e+00	2.111	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	2.17e-01	1.00e+00	2.040	1	4	125
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.22e-01	1.00e+00	1.173	2	29	456
GO:0006184	GTP catabolic process	2.25e-01	1.00e+00	1.983	1	7	130
GO:0005737	cytoplasm	2.32e-01	1.00e+00	0.450	7	127	2633
GO:0044212	transcription regulatory region DNA binding	2.45e-01	1.00e+00	1.846	1	13	143
GO:0005622	intracellular	2.48e-01	1.00e+00	1.826	1	2	145
GO:0001701	in utero embryonic development	2.61e-01	1.00e+00	1.739	1	7	154
GO:0046872	metal ion binding	2.71e-01	1.00e+00	0.723	3	24	934
GO:0005874	microtubule	2.74e-01	1.00e+00	1.657	1	10	163
GO:0005634	nucleus	2.76e-01	1.00e+00	0.341	8	158	3246
GO:0000166	nucleotide binding	2.92e-01	1.00e+00	1.546	1	13	176
GO:0004842	ubiquitin-protein transferase activity	2.97e-01	1.00e+00	1.522	1	17	179
GO:0005743	mitochondrial inner membrane	3.21e-01	1.00e+00	1.383	1	9	197
GO:0005525	GTP binding	3.21e-01	1.00e+00	1.383	1	12	197
GO:0006281	DNA repair	3.29e-01	1.00e+00	1.340	1	24	203
GO:0030154	cell differentiation	3.31e-01	1.00e+00	1.333	1	5	204
GO:0019899	enzyme binding	3.39e-01	1.00e+00	1.291	1	7	210
GO:0043231	intracellular membrane-bounded organelle	3.49e-01	1.00e+00	1.237	1	8	218
GO:0003682	chromatin binding	3.92e-01	1.00e+00	1.028	1	15	252
GO:0006355	regulation of transcription, DNA-templated	4.10e-01	1.00e+00	0.524	2	31	715
GO:0008270	zinc ion binding	4.19e-01	1.00e+00	0.500	2	39	727
GO:0008285	negative regulation of cell proliferation	4.21e-01	1.00e+00	0.892	1	11	277
GO:0008284	positive regulation of cell proliferation	4.24e-01	1.00e+00	0.881	1	8	279
GO:0005730	nucleolus	4.28e-01	1.00e+00	0.341	3	74	1217
GO:0000278	mitotic cell cycle	4.63e-01	1.00e+00	0.711	1	28	314
GO:0042802	identical protein binding	5.05e-01	1.00e+00	0.538	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	5.27e-01	1.00e+00	0.447	1	21	377
GO:0005524	ATP binding	5.29e-01	1.00e+00	0.205	2	37	892
GO:0005783	endoplasmic reticulum	5.31e-01	1.00e+00	0.432	1	12	381
GO:0006351	transcription, DNA-templated	6.35e-01	1.00e+00	-0.066	2	47	1076
GO:0070062	extracellular vesicular exosome	6.42e-01	1.00e+00	-0.090	3	51	1641
GO:0005887	integral component of plasma membrane	6.85e-01	1.00e+00	-0.162	1	8	575
GO:0007165	signal transduction	7.12e-01	1.00e+00	-0.266	1	24	618
GO:0044281	small molecule metabolic process	8.21e-01	1.00e+00	-0.716	1	35	844
GO:0005886	plasma membrane	8.87e-01	1.00e+00	-0.795	2	46	1784

chia-Fav

reg-snw-28985

Statistics

Genes (19)

Interactions (21)

Related GO terms (191)