int-snw-54514

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.806 3.40e-15 6.83e-04 4.32e-03
chia-screen-data-Fav-int-snw-54514 subnetwork

Genes (18)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
EP300 2033 22-2.2743.120415YesYes
LARS 51520 14-2.5743.157105YesYes
YAP1 10413 94-4.2563.53853Yes-
HES6 55502 8-2.5573.12011YesYes
POU5F1 5460 133-5.1483.538179YesYes
TPR 7175 18-2.6383.07228YesYes
PSMD2 5708 47-4.1723.157386YesYes
APLP2 334 12-2.7323.20635YesYes
[ DDX4 ] 54514 1-1.2452.80613--
ZFP36 7538 10-2.9682.86924YesYes
NFKB1 4790 9-2.1232.870263Yes-
HNRNPD 3184 5-2.1533.117123Yes-
NFRKB 4798 48-3.1293.10823YesYes
YY1 7528 24-2.5723.120114YesYes
TPM1 7168 2-2.6862.95744YesYes
HNRNPU 3192 76-2.8693.538139Yes-
DDIT3 1649 60-2.8253.504343YesYes
CARM1 10498 1-1.5832.80668--

Interactions (26)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
TPM1 7168 DDX4 54514 pp -- int.I2D: BioGrid_Fly
NFRKB 4798 YY1 7528 pp -- int.I2D: BioGrid
EP300 2033 NFKB1 4790 pp -- int.I2D: BioGrid
TPM1 7168 LARS 51520 pp -- int.I2D: IntAct_Worm
HNRNPD 3184 HNRNPU 3192 pp -- int.Mint: MI:0915(physical association)
EP300 2033 HNRNPU 3192 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vitro, in vivo
EP300 2033 YY1 7528 pp -- int.I2D: BioGrid, BCI, HPRD;
int.Transfac: -;
int.Ravasi: -;
int.HPRD: in vivo;
int.DIP: MI:0218(physical interaction)
DDIT3 1649 NFKB1 4790 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
PSMD2 5708 LARS 51520 pp -- int.I2D: BioGrid_Yeast
NFKB1 4790 CARM1 10498 pp -- int.I2D: BioGrid
NFKB1 4790 YY1 7528 pp -- int.Intact: MI:0915(physical association)
NFRKB 4798 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
EP300 2033 HES6 55502 pp -- int.I2D: IntAct
NFKB1 4790 NFRKB 4798 pp -- int.I2D: BCI, HPRD;
int.Ravasi: -;
int.HPRD: in vitro
DDIT3 1649 EP300 2033 pp -- int.Intact: MI:0915(physical association)
DDIT3 1649 HNRNPD 3184 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
CARM1 10498 DDX4 54514 pp -- int.I2D: BioGrid_Fly
EP300 2033 CARM1 10498 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vivo
EP300 2033 YAP1 10413 pp -- int.I2D: BioGrid
HNRNPD 3184 CARM1 10498 pp -- int.I2D: BioGrid_Fly
APLP2 334 NFKB1 4790 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
NFKB1 4790 TPR 7175 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
NFKB1 4790 ZFP36 7538 pp -- int.I2D: BioGrid
DDIT3 1649 HNRNPU 3192 pp -- int.I2D: BEHRENDS_AUTOPHAGY_LOW

Related GO terms (431)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0044212transcription regulatory region DNA binding3.78e-085.45e-044.839617168
GO:0005654nucleoplasm1.36e-071.96e-032.88910641082
GO:0005634nucleus7.38e-071.07e-021.492161594559
GO:0003677DNA binding5.11e-067.37e-022.5669491218
GO:0008134transcription factor binding9.15e-061.32e-014.049518242
GO:0006355regulation of transcription, DNA-templated1.19e-051.71e-012.685843997
GO:0005667transcription factor complex5.61e-058.09e-014.195417175
GO:0010467gene expression1.12e-041.00e+002.845645669
GO:0042789mRNA transcription from RNA polymerase II promoter1.14e-041.00e+006.9462213
GO:0051019mitogen-activated protein kinase binding1.14e-041.00e+006.9462213
GO:0031011Ino80 complex1.33e-041.00e+006.8392614
GO:0003700sequence-specific DNA binding transcription factor activity1.43e-041.00e+002.782639699
GO:0003713transcription coactivator activity1.81e-041.00e+003.757424237
GO:0005829cytosol2.68e-041.00e+001.68310862496
GO:0005515protein binding3.76e-041.00e+000.997151986024
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.29e-041.00e+002.813537570
GO:0042594response to starvation6.70e-041.00e+005.6922431
GO:0031072heat shock protein binding7.59e-041.00e+005.6022233
GO:0006974cellular response to DNA damage stimulus8.18e-041.00e+003.99337151
GO:0003065positive regulation of heart rate by epinephrine1.25e-031.00e+009.646111
GO:1901673regulation of spindle assembly involved in mitosis1.25e-031.00e+009.646111
GO:0060350endochondral bone morphogenesis1.25e-031.00e+009.646111
GO:0043578nuclear matrix organization1.25e-031.00e+009.646111
GO:2000016negative regulation of determination of dorsal identity1.25e-031.00e+009.646111
GO:1901985positive regulation of protein acetylation1.25e-031.00e+009.646111
GO:0010965regulation of mitotic sister chromatid separation1.25e-031.00e+009.646111
GO:0034971histone H3-R17 methylation1.25e-031.00e+009.646111
GO:0043969histone H2B acetylation1.25e-031.00e+009.646111
GO:0035642histone methyltransferase activity (H3-R17 specific)1.25e-031.00e+009.646111
GO:0045083negative regulation of interleukin-12 biosynthetic process1.25e-031.00e+009.646111
GO:0006404RNA import into nucleus1.25e-031.00e+009.646111
GO:0090308regulation of methylation-dependent chromatin silencing1.25e-031.00e+009.646111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway1.25e-031.00e+009.646111
GO:0060965negative regulation of gene silencing by miRNA1.25e-031.00e+009.646111
GO:0060795cell fate commitment involved in formation of primary germ layer1.25e-031.00e+009.646111
GO:0060177regulation of angiotensin metabolic process1.25e-031.00e+009.646111
GO:2000629negative regulation of miRNA metabolic process1.25e-031.00e+009.646111
GO:0031453positive regulation of heterochromatin assembly1.25e-031.00e+009.646111
GO:0003714transcription corepressor activity1.32e-031.00e+003.755311178
GO:0045727positive regulation of translation1.35e-031.00e+005.1872244
GO:0050728negative regulation of inflammatory response2.18e-031.00e+004.8392356
GO:0006396RNA processing2.41e-031.00e+004.7642559
GO:0006429leucyl-tRNA aminoacylation2.49e-031.00e+008.646112
GO:0060242contact inhibition2.49e-031.00e+008.646112
GO:0031990mRNA export from nucleus in response to heat stress2.49e-031.00e+008.646122
GO:0006403RNA localization2.49e-031.00e+008.646112
GO:0003420regulation of growth plate cartilage chondrocyte proliferation2.49e-031.00e+008.646112
GO:0009786regulation of asymmetric cell division2.49e-031.00e+008.646112
GO:0070840dynein complex binding2.49e-031.00e+008.646112
GO:0090043regulation of tubulin deacetylation2.49e-031.00e+008.646122
GO:0071389cellular response to mineralocorticoid stimulus2.49e-031.00e+008.646112
GO:0009405pathogenesis2.49e-031.00e+008.646112
GO:0046832negative regulation of RNA export from nucleus2.49e-031.00e+008.646112
GO:1990440positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress2.49e-031.00e+008.646112
GO:0034696response to prostaglandin F2.49e-031.00e+008.646112
GO:0000189MAPK import into nucleus2.49e-031.00e+008.646112
GO:0034970histone H3-R2 methylation2.49e-031.00e+008.646112
GO:0014737positive regulation of muscle atrophy2.49e-031.00e+008.646112
GO:0008013beta-catenin binding2.49e-031.00e+004.7392960
GO:0035984cellular response to trichostatin A2.49e-031.00e+008.646112
GO:0004823leucine-tRNA ligase activity2.49e-031.00e+008.646112
GO:0044324regulation of transcription involved in anterior/posterior axis specification2.49e-031.00e+008.646112
GO:0016071mRNA metabolic process2.51e-031.00e+003.43038223
GO:0032481positive regulation of type I interferon production2.58e-031.00e+004.7152661
GO:0016070RNA metabolic process3.35e-031.00e+003.28338247
GO:0003729mRNA binding3.57e-031.00e+004.4762472
GO:0018076N-terminal peptidyl-lysine acetylation3.74e-031.00e+008.061113
GO:0046914transition metal ion binding3.74e-031.00e+008.061113
GO:0042306regulation of protein import into nucleus3.74e-031.00e+008.061123
GO:0060913cardiac cell fate determination3.74e-031.00e+008.061113
GO:1900127positive regulation of hyaluronan biosynthetic process3.74e-031.00e+008.061113
GO:0050779RNA destabilization3.74e-031.00e+008.061113
GO:0010560positive regulation of glycoprotein biosynthetic process3.74e-031.00e+008.061113
GO:0010956negative regulation of calcidiol 1-monooxygenase activity3.74e-031.00e+008.061113
GO:0033146regulation of intracellular estrogen receptor signaling pathway3.74e-031.00e+008.061113
GO:0033256I-kappaB/NF-kappaB complex3.74e-031.00e+008.061113
GO:0006405RNA export from nucleus3.74e-031.00e+008.061123
GO:0003130BMP signaling pathway involved in heart induction3.74e-031.00e+008.061113
GO:0016032viral process3.76e-031.00e+002.585426534
GO:0032680regulation of tumor necrosis factor production4.98e-031.00e+007.646114
GO:0032375negative regulation of cholesterol transport4.98e-031.00e+007.646114
GO:0097157pre-mRNA intronic binding4.98e-031.00e+007.646114
GO:0018393internal peptidyl-lysine acetylation4.98e-031.00e+007.646114
GO:0016274protein-arginine N-methyltransferase activity4.98e-031.00e+007.646114
GO:0071547piP-body4.98e-031.00e+007.646114
GO:0010957negative regulation of vitamin D biosynthetic process4.98e-031.00e+007.646114
GO:0097167circadian regulation of translation4.98e-031.00e+007.646114
GO:0032269negative regulation of cellular protein metabolic process4.98e-031.00e+007.646114
GO:2000630positive regulation of miRNA metabolic process4.98e-031.00e+007.646114
GO:0006999nuclear pore organization4.98e-031.00e+007.646114
GO:0005862muscle thin filament tropomyosin4.98e-031.00e+007.646114
GO:0044615nuclear pore nuclear basket4.98e-031.00e+007.646114
GO:0001714endodermal cell fate specification6.23e-031.00e+007.324115
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint6.23e-031.00e+007.324115
GO:0004468lysine N-acetyltransferase activity, acting on acetyl phosphate as donor6.23e-031.00e+007.324115
GO:0019957C-C chemokine binding6.23e-031.00e+007.324115
GO:0043620regulation of DNA-templated transcription in response to stress6.23e-031.00e+007.324115
GO:0070934CRD-mediated mRNA stabilization6.23e-031.00e+007.324125
GO:0010884positive regulation of lipid storage6.23e-031.00e+007.324115
GO:0035925mRNA 3'-UTR AU-rich region binding6.23e-031.00e+007.324115
GO:0065004protein-DNA complex assembly6.23e-031.00e+007.324115
GO:0071546pi-body6.23e-031.00e+007.324115
GO:0008276protein methyltransferase activity6.23e-031.00e+007.324115
GO:0010793regulation of mRNA export from nucleus6.23e-031.00e+007.324115
GO:0060298positive regulation of sarcomere organization6.23e-031.00e+007.324115
GO:0070849response to epidermal growth factor6.23e-031.00e+007.324115
GO:0007176regulation of epidermal growth factor-activated receptor activity6.23e-031.00e+007.324115
GO:0032025response to cobalt ion6.23e-031.00e+007.324115
GO:0070937CRD-mediated mRNA stability complex7.47e-031.00e+007.061136
GO:0008469histone-arginine N-methyltransferase activity7.47e-031.00e+007.061116
GO:0044822poly(A) RNA binding7.99e-031.00e+001.9245501056
GO:0003723RNA binding8.28e-031.00e+002.813318342
GO:0030529ribonucleoprotein complex8.43e-031.00e+003.83925112
GO:0046825regulation of protein export from nucleus8.71e-031.00e+006.839127
GO:0071354cellular response to interleukin-68.71e-031.00e+006.839127
GO:0032059bleb8.71e-031.00e+006.839117
GO:0002161aminoacyl-tRNA editing activity8.71e-031.00e+006.839127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity8.71e-031.00e+006.839117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine8.71e-031.00e+006.839117
GO:0006475internal protein amino acid acetylation8.71e-031.00e+006.839117
GO:0042054histone methyltransferase activity9.94e-031.00e+006.646138
GO:0051292nuclear pore complex assembly9.94e-031.00e+006.646148
GO:0007617mating behavior9.94e-031.00e+006.646118
GO:0001955blood vessel maturation9.94e-031.00e+006.646118
GO:0071316cellular response to nicotine9.94e-031.00e+006.646118
GO:0035457cellular response to interferon-alpha9.94e-031.00e+006.646118
GO:0042405nuclear inclusion body1.12e-021.00e+006.476129
GO:0006450regulation of translational fidelity1.12e-021.00e+006.476129
GO:0035259glucocorticoid receptor binding1.12e-021.00e+006.476119
GO:0000975regulatory region DNA binding1.12e-021.00e+006.476129
GO:0045793positive regulation of cell size1.12e-021.00e+006.476129
GO:0060765regulation of androgen receptor signaling pathway1.12e-021.00e+006.476119
GO:0010225response to UV-C1.12e-021.00e+006.476129
GO:0035278negative regulation of translation involved in gene silencing by miRNA1.12e-021.00e+006.476119
GO:0006983ER overload response1.12e-021.00e+006.476119
GO:0043495protein anchor1.12e-021.00e+006.476119
GO:0000400four-way junction DNA binding1.12e-021.00e+006.476119
GO:0000278mitotic cell cycle1.19e-021.00e+002.620315391
GO:1900153positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.24e-021.00e+006.3241210
GO:0035413positive regulation of catenin import into nucleus1.24e-021.00e+006.3241210
GO:0016407acetyltransferase activity1.24e-021.00e+006.3241210
GO:0045662negative regulation of myoblast differentiation1.36e-021.00e+006.1871311
GO:0060213positive regulation of nuclear-transcribed mRNA poly(A) tail shortening1.36e-021.00e+006.1871211
GO:0043923positive regulation by host of viral transcription1.36e-021.00e+006.1871111
GO:0033160positive regulation of protein import into nucleus, translocation1.36e-021.00e+006.1871311
GO:0042162telomeric DNA binding1.36e-021.00e+006.1871111
GO:0042975peroxisome proliferator activated receptor binding1.36e-021.00e+006.1871111
GO:0033391chromatoid body1.36e-021.00e+006.1871111
GO:0060391positive regulation of SMAD protein import into nucleus1.36e-021.00e+006.1871411
GO:0006366transcription from RNA polymerase II promoter1.44e-021.00e+002.520330419
GO:0045944positive regulation of transcription from RNA polymerase II promoter1.47e-021.00e+002.022441789
GO:0006878cellular copper ion homeostasis1.49e-021.00e+006.0611112
GO:0006402mRNA catabolic process1.49e-021.00e+006.0611112
GO:0045947negative regulation of translational initiation1.49e-021.00e+006.0611212
GO:00709353'-UTR-mediated mRNA stabilization1.49e-021.00e+006.0611312
GO:0034399nuclear periphery1.49e-021.00e+006.0611512
GO:0005838proteasome regulatory particle1.49e-021.00e+006.0611112
GO:0035198miRNA binding1.49e-021.00e+006.0611112
GO:0071480cellular response to gamma radiation1.61e-021.00e+005.9461113
GO:0016746transferase activity, transferring acyl groups1.61e-021.00e+005.9461113
GO:0046688response to copper ion1.61e-021.00e+005.9461113
GO:0006937regulation of muscle contraction1.61e-021.00e+005.9461113
GO:0043488regulation of mRNA stability1.61e-021.00e+005.9461113
GO:0005868cytoplasmic dynein complex1.61e-021.00e+005.9461113
GO:0030234enzyme regulator activity1.61e-021.00e+005.9461213
GO:0046827positive regulation of protein export from nucleus1.61e-021.00e+005.9461113
GO:0010744positive regulation of macrophage derived foam cell differentiation1.73e-021.00e+005.8391114
GO:0001967suckling behavior1.73e-021.00e+005.8391114
GO:0031293membrane protein intracellular domain proteolysis1.73e-021.00e+005.8391114
GO:0017091AU-rich element binding1.73e-021.00e+005.8391214
GO:0070542response to fatty acid1.73e-021.00e+005.8391114
GO:0034614cellular response to reactive oxygen species1.73e-021.00e+005.8391214
GO:0006401RNA catabolic process1.73e-021.00e+005.8391114
GO:0071375cellular response to peptide hormone stimulus1.73e-021.00e+005.8391214
GO:0032993protein-DNA complex1.73e-021.00e+005.8391214
GO:0005487nucleocytoplasmic transporter activity1.73e-021.00e+005.8391314
GO:0000398mRNA splicing, via spliceosome1.74e-021.00e+003.289215164
GO:0042307positive regulation of protein import into nucleus1.86e-021.00e+005.7391415
GO:0016571histone methylation1.86e-021.00e+005.7391215
GO:0031529ruffle organization1.86e-021.00e+005.7391115
GO:0001824blastocyst development1.86e-021.00e+005.7391215
GO:1990090cellular response to nerve growth factor stimulus1.86e-021.00e+005.7391115
GO:0042176regulation of protein catabolic process1.98e-021.00e+005.6461216
GO:0007141male meiosis I1.98e-021.00e+005.6461116
GO:0051276chromosome organization1.98e-021.00e+005.6461216
GO:0045638negative regulation of myeloid cell differentiation1.98e-021.00e+005.6461116
GO:0048593camera-type eye morphogenesis1.98e-021.00e+005.6461116
GO:0045893positive regulation of transcription, DNA-templated2.04e-021.00e+002.330324478
GO:0090316positive regulation of intracellular protein transport2.10e-021.00e+005.5591217
GO:0022624proteasome accessory complex2.10e-021.00e+005.5591117
GO:0070577lysine-acetylated histone binding2.10e-021.00e+005.5591117
GO:007188914-3-3 protein binding2.22e-021.00e+005.4761218
GO:0030520intracellular estrogen receptor signaling pathway2.22e-021.00e+005.4761418
GO:0045773positive regulation of axon extension2.22e-021.00e+005.4761118
GO:0033613activating transcription factor binding2.22e-021.00e+005.4761318
GO:0035257nuclear hormone receptor binding2.35e-021.00e+005.3981119
GO:0071549cellular response to dexamethasone stimulus2.47e-021.00e+005.3241320
GO:0010942positive regulation of cell death2.47e-021.00e+005.3241120
GO:0032757positive regulation of interleukin-8 production2.47e-021.00e+005.3241120
GO:0043393regulation of protein binding2.47e-021.00e+005.3241120
GO:0005737cytoplasm2.55e-021.00e+000.93791243767
GO:0032967positive regulation of collagen biosynthetic process2.59e-021.00e+005.2541321
GO:0045862positive regulation of proteolysis2.59e-021.00e+005.2541221
GO:0000123histone acetyltransferase complex2.59e-021.00e+005.2541621
GO:0003823antigen binding2.71e-021.00e+005.1871222
GO:0031941filamentous actin2.71e-021.00e+005.1871222
GO:0036464cytoplasmic ribonucleoprotein granule2.71e-021.00e+005.1871222
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2.83e-021.00e+005.1231123
GO:0006351transcription, DNA-templated2.84e-021.00e+001.4705571446
GO:0032781positive regulation of ATPase activity2.95e-021.00e+005.0611124
GO:0043388positive regulation of DNA binding2.95e-021.00e+005.0611224
GO:0055010ventricular cardiac muscle tissue morphogenesis2.95e-021.00e+005.0611124
GO:0043425bHLH transcription factor binding2.95e-021.00e+005.0611124
GO:0006915apoptotic process3.01e-021.00e+002.115312555
GO:0006611protein export from nucleus3.08e-021.00e+005.0021325
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening3.08e-021.00e+005.0021325
GO:0031519PcG protein complex3.08e-021.00e+005.0021125
GO:0051059NF-kappaB binding3.08e-021.00e+005.0021325
GO:0035329hippo signaling3.20e-021.00e+004.9461526
GO:0000976transcription regulatory region sequence-specific DNA binding3.20e-021.00e+004.9461326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.20e-021.00e+004.9461126
GO:0051209release of sequestered calcium ion into cytosol3.20e-021.00e+004.9461126
GO:0048565digestive tract development3.20e-021.00e+004.9461226
GO:0045214sarcomere organization3.20e-021.00e+004.9461226
GO:0008380RNA splicing3.22e-021.00e+002.813222228
GO:0007399nervous system development3.30e-021.00e+002.79426231
GO:0015631tubulin binding3.32e-021.00e+004.8911227
GO:0034612response to tumor necrosis factor3.32e-021.00e+004.8911227
GO:0043967histone H4 acetylation3.32e-021.00e+004.8911127
GO:0003727single-stranded RNA binding3.44e-021.00e+004.8391228
GO:0050714positive regulation of protein secretion3.44e-021.00e+004.8391328
GO:0034605cellular response to heat3.44e-021.00e+004.8391128
GO:0030901midbrain development3.56e-021.00e+004.7881129
GO:0072686mitotic spindle3.56e-021.00e+004.7881329
GO:0042803protein homodimerization activity3.59e-021.00e+002.014319595
GO:0006606protein import into nucleus3.68e-021.00e+004.7391230
GO:0031647regulation of protein stability3.68e-021.00e+004.7391430
GO:0010827regulation of glucose transport3.68e-021.00e+004.7391430
GO:0034644cellular response to UV3.68e-021.00e+004.7391130
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator3.68e-021.00e+004.7391130
GO:0008016regulation of heart contraction3.68e-021.00e+004.7391130
GO:0010494cytoplasmic stress granule3.68e-021.00e+004.7391230
GO:0007094mitotic spindle assembly checkpoint3.80e-021.00e+004.6921331
GO:0071347cellular response to interleukin-13.80e-021.00e+004.6921231
GO:0032091negative regulation of protein binding3.92e-021.00e+004.6461332
GO:0043491protein kinase B signaling3.92e-021.00e+004.6461232
GO:1903507negative regulation of nucleic acid-templated transcription3.92e-021.00e+004.6461232
GO:0045600positive regulation of fat cell differentiation3.92e-021.00e+004.6461232
GO:0001756somitogenesis4.04e-021.00e+004.6021133
GO:0071333cellular response to glucose stimulus4.04e-021.00e+004.6021133
GO:0030317sperm motility4.04e-021.00e+004.6021133
GO:0007283spermatogenesis4.15e-021.00e+002.61323262
GO:0030017sarcomere4.16e-021.00e+004.5591234
GO:0006357regulation of transcription from RNA polymerase II promoter4.21e-021.00e+002.602223264
GO:0007077mitotic nuclear envelope disassembly4.40e-021.00e+004.4761436
GO:0001102RNA polymerase II activating transcription factor binding4.40e-021.00e+004.4761136
GO:0032880regulation of protein localization4.52e-021.00e+004.4371237
GO:0042752regulation of circadian rhythm4.52e-021.00e+004.4371337
GO:0006954inflammatory response4.59e-021.00e+002.53226277
GO:0030049muscle filament sliding4.64e-021.00e+004.3981338
GO:0031490chromatin DNA binding4.64e-021.00e+004.3981238
GO:0051496positive regulation of stress fiber assembly4.64e-021.00e+004.3981438
GO:0032092positive regulation of protein binding4.64e-021.00e+004.3981238
GO:0050681androgen receptor binding4.64e-021.00e+004.3981138
GO:0008645hexose transport4.76e-021.00e+004.3611439
GO:0008026ATP-dependent helicase activity4.76e-021.00e+004.3611139
GO:0060048cardiac muscle contraction4.76e-021.00e+004.3611139
GO:0045785positive regulation of cell adhesion4.88e-021.00e+004.3241240
GO:0046332SMAD binding4.88e-021.00e+004.3241240
GO:0071320cellular response to cAMP4.88e-021.00e+004.3241140
GO:0035019somatic stem cell maintenance4.88e-021.00e+004.3241640
GO:0050885neuromuscular process controlling balance4.88e-021.00e+004.3241240
GO:0007519skeletal muscle tissue development4.88e-021.00e+004.3241240
GO:0070301cellular response to hydrogen peroxide5.00e-021.00e+004.2891241
GO:0008307structural constituent of muscle5.00e-021.00e+004.2891241
GO:0006418tRNA aminoacylation for protein translation5.12e-021.00e+004.2541342
GO:0019898extrinsic component of membrane5.12e-021.00e+004.2541242
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity5.24e-021.00e+004.2201743
GO:0004402histone acetyltransferase activity5.24e-021.00e+004.2201643
GO:0030154cell differentiation5.33e-021.00e+002.41325301
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding5.35e-021.00e+004.1871444
GO:0003712transcription cofactor activity5.35e-021.00e+004.1871844
GO:0051591response to cAMP5.47e-021.00e+004.1541445
GO:0043966histone H3 acetylation5.47e-021.00e+004.1541545
GO:0001047core promoter binding5.47e-021.00e+004.1541545
GO:0043525positive regulation of neuron apoptotic process5.59e-021.00e+004.1231446
GO:0008092cytoskeletal protein binding5.71e-021.00e+004.0921147
GO:0090263positive regulation of canonical Wnt signaling pathway5.83e-021.00e+004.0611348
GO:0030900forebrain development5.95e-021.00e+004.0311149
GO:0035690cellular response to drug5.95e-021.00e+004.0311349
GO:0006521regulation of cellular amino acid metabolic process6.06e-021.00e+004.0021150
GO:0006986response to unfolded protein6.06e-021.00e+004.0021450
GO:0034976response to endoplasmic reticulum stress6.18e-021.00e+003.9741251
GO:0045454cell redox homeostasis6.18e-021.00e+003.9741151
GO:0003682chromatin binding6.18e-021.00e+002.293219327
GO:0009611response to wounding6.30e-021.00e+003.9461552
GO:0007623circadian rhythm6.42e-021.00e+003.9181153
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay6.42e-021.00e+003.9181453
GO:0051592response to calcium ion6.65e-021.00e+003.8651155
GO:0002039p53 binding6.65e-021.00e+003.8651455
GO:0015758glucose transport6.65e-021.00e+003.8651455
GO:0001725stress fiber6.65e-021.00e+003.8651455
GO:0071300cellular response to retinoic acid6.65e-021.00e+003.8651155
GO:0000724double-strand break repair via homologous recombination6.65e-021.00e+003.8651255
GO:0043627response to estrogen6.77e-021.00e+003.8391556
GO:0043565sequence-specific DNA binding6.82e-021.00e+002.212211346
GO:0008203cholesterol metabolic process6.88e-021.00e+003.8131257
GO:0005643nuclear pore6.88e-021.00e+003.81311157
GO:0000502proteasome complex7.00e-021.00e+003.7881358
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity7.12e-021.00e+003.7641659
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription7.12e-021.00e+003.7641559
GO:0006987activation of signaling protein activity involved in unfolded protein response7.35e-021.00e+003.7151261
GO:0004867serine-type endopeptidase inhibitor activity7.58e-021.00e+003.6691363
GO:0000776kinetochore7.58e-021.00e+003.6691563
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process7.58e-021.00e+003.6691463
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest7.70e-021.00e+003.6461164
GO:0042060wound healing7.70e-021.00e+003.6461264
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.81e-021.00e+003.6241265
GO:0006310DNA recombination7.81e-021.00e+003.6241765
GO:0071260cellular response to mechanical stimulus7.81e-021.00e+003.6241465
GO:0034166toll-like receptor 10 signaling pathway7.81e-021.00e+003.6241465
GO:0034146toll-like receptor 5 signaling pathway7.81e-021.00e+003.6241465
GO:0010468regulation of gene expression8.16e-021.00e+003.5591268
GO:0032587ruffle membrane8.39e-021.00e+003.5171370
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.39e-021.00e+003.5171270
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway8.50e-021.00e+003.4961471
GO:0007626locomotory behavior8.50e-021.00e+003.4961271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway8.50e-021.00e+003.4961471
GO:0034162toll-like receptor 9 signaling pathway8.62e-021.00e+003.4761472
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent8.62e-021.00e+003.4761172
GO:0030324lung development8.62e-021.00e+003.4761172
GO:0034134toll-like receptor 2 signaling pathway8.73e-021.00e+003.4561473
GO:0000785chromatin8.73e-021.00e+003.4561673
GO:0002020protease binding8.85e-021.00e+003.4371674
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity8.85e-021.00e+003.4371474
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.85e-021.00e+003.4371274
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process8.96e-021.00e+003.4171175
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I8.96e-021.00e+003.4171175
GO:0035666TRIF-dependent toll-like receptor signaling pathway9.08e-021.00e+003.3981376
GO:0001889liver development9.19e-021.00e+003.3791377
GO:0030336negative regulation of cell migration9.30e-021.00e+003.3611178
GO:0071013catalytic step 2 spliceosome9.30e-021.00e+003.3611778
GO:0002756MyD88-independent toll-like receptor signaling pathway9.30e-021.00e+003.3611378
GO:0034138toll-like receptor 3 signaling pathway9.42e-021.00e+003.3421379
GO:0030968endoplasmic reticulum unfolded protein response9.42e-021.00e+003.3421279
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process9.42e-021.00e+003.3421279
GO:0002755MyD88-dependent toll-like receptor signaling pathway9.53e-021.00e+003.3241580
GO:0071222cellular response to lipopolysaccharide9.65e-021.00e+003.3061481
GO:0043066negative regulation of apoptotic process9.68e-021.00e+001.918216424
GO:0009653anatomical structure morphogenesis9.87e-021.00e+003.2711283
GO:0009952anterior/posterior pattern specification9.87e-021.00e+003.2711483
GO:0050852T cell receptor signaling pathway1.01e-011.00e+003.2371285
GO:0009887organ morphogenesis1.02e-011.00e+003.2201586
GO:0003690double-stranded DNA binding1.02e-011.00e+003.2201386
GO:0090090negative regulation of canonical Wnt signaling pathway1.02e-011.00e+003.2201886
GO:0045471response to ethanol1.02e-011.00e+003.2201386
GO:0006979response to oxidative stress1.03e-011.00e+003.2031687
GO:0006936muscle contraction1.03e-011.00e+003.2031387
GO:0016363nuclear matrix1.08e-011.00e+003.1381691
GO:0007010cytoskeleton organization1.08e-011.00e+003.1381491
GO:0006928cellular component movement1.08e-011.00e+003.1381391
GO:0005200structural constituent of cytoskeleton1.08e-011.00e+003.1381691
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.09e-011.00e+003.1231192
GO:0001649osteoblast differentiation1.09e-011.00e+003.1231592
GO:0071456cellular response to hypoxia1.09e-011.00e+003.1231392
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.09e-011.00e+003.1231792
GO:0005770late endosome1.10e-011.00e+003.1071293
GO:0034142toll-like receptor 4 signaling pathway1.13e-011.00e+003.0611496
GO:0051726regulation of cell cycle1.14e-011.00e+003.0461597
GO:0001934positive regulation of protein phosphorylation1.22e-011.00e+002.94615104
GO:0010951negative regulation of endopeptidase activity1.22e-011.00e+002.94616104
GO:0003676nucleic acid binding1.26e-011.00e+002.90512107
GO:0002224toll-like receptor signaling pathway1.28e-011.00e+002.87814109
GO:0005635nuclear envelope1.32e-011.00e+002.82615113
GO:0000209protein polyubiquitination1.35e-011.00e+002.78813116
GO:0046983protein dimerization activity1.38e-011.00e+002.76415118
GO:0006325chromatin organization1.38e-011.00e+002.764112118
GO:0005730nucleolus1.40e-011.00e+000.9664661641
GO:0007219Notch signaling pathway1.40e-011.00e+002.73915120
GO:0008201heparin binding1.42e-011.00e+002.71511122
GO:0051092positive regulation of NF-kappaB transcription factor activity1.44e-011.00e+002.69215124
GO:0007050cell cycle arrest1.44e-011.00e+002.69215124
GO:0005215transporter activity1.50e-011.00e+002.62413130
GO:0044255cellular lipid metabolic process1.54e-011.00e+002.59112133
GO:0000086G2/M transition of mitotic cell cycle1.57e-011.00e+002.55914136
GO:0016055Wnt signaling pathway1.59e-011.00e+002.53814138
GO:0007507heart development1.60e-011.00e+002.52717139
GO:0045087innate immune response1.69e-011.00e+001.427215596
GO:0001666response to hypoxia1.71e-011.00e+002.42717149
GO:0000082G1/S transition of mitotic cell cycle1.71e-011.00e+002.42713149
GO:0042981regulation of apoptotic process1.72e-011.00e+002.41714150
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.87e-011.00e+002.280112165
GO:0044281small molecule metabolic process1.88e-011.00e+000.9893201211
GO:0038095Fc-epsilon receptor signaling pathway1.90e-011.00e+002.25415168
GO:0031965nuclear membrane1.90e-011.00e+002.254110168
GO:0034641cellular nitrogen compound metabolic process1.93e-011.00e+002.22812171
GO:0031625ubiquitin protein ligase binding2.00e-011.00e+002.17015178
GO:0032403protein complex binding2.05e-011.00e+002.13016183
GO:0006367transcription initiation from RNA polymerase II promoter2.06e-011.00e+002.123122184
GO:0005524ATP binding2.17e-011.00e+000.8893311298
GO:0001701in utero embryonic development2.23e-011.00e+001.99518201
GO:0019221cytokine-mediated signaling pathway2.43e-011.00e+001.85818221
GO:0007067mitotic nuclear division2.49e-011.00e+001.82016227
GO:0005975carbohydrate metabolic process2.73e-011.00e+001.66318253
GO:0000166nucleotide binding2.78e-011.00e+001.629113259
GO:0006281DNA repair2.80e-011.00e+001.618114261
GO:0003779actin binding2.85e-011.00e+001.591110266
GO:0048011neurotrophin TRK receptor signaling pathway2.88e-011.00e+001.57517269
GO:0030198extracellular matrix organization3.00e-011.00e+001.50216283
GO:0007186G-protein coupled receptor signaling pathway3.05e-011.00e+001.47111289
GO:0005856cytoskeleton3.07e-011.00e+001.46119291
GO:0006200ATP catabolic process3.08e-011.00e+001.45612292
GO:0035556intracellular signal transduction3.18e-011.00e+001.40319303
GO:0007275multicellular organismal development3.29e-011.00e+001.34217316
GO:0019901protein kinase binding3.30e-011.00e+001.338118317
GO:0008283cell proliferation3.39e-011.00e+001.289114328
GO:0016020membrane3.51e-011.00e+000.5163461681
GO:0008270zinc ion binding3.56e-011.00e+000.685227997
GO:0046982protein heterodimerization activity3.82e-011.00e+001.07618380
GO:0008284positive regulation of cell proliferation3.83e-011.00e+001.069110382
GO:0009986cell surface3.99e-011.00e+000.99519402
GO:0045892negative regulation of transcription, DNA-templated4.07e-011.00e+000.956124413
GO:0055085transmembrane transport4.24e-011.00e+000.88118435
GO:0044267cellular protein metabolic process4.52e-011.00e+000.757120474
GO:0042802identical protein binding4.59e-011.00e+000.727119484
GO:0048471perinuclear region of cytoplasm4.72e-011.00e+000.67518502
GO:0070062extracellular vesicular exosome5.96e-011.00e+000.0023572400
GO:0005739mitochondrion7.25e-011.00e+00-0.317123998
GO:0046872metal ion binding8.19e-011.00e+00-0.7061291307
GO:0016021integral component of membrane9.30e-011.00e+00-1.3071171982
GO:0005886plasma membrane9.71e-011.00e+00-1.6881492582