Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.806 | 3.40e-15 | 6.83e-04 | 4.32e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
LARS | 51520 | 14 | -2.574 | 3.157 | 105 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
HES6 | 55502 | 8 | -2.557 | 3.120 | 11 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
TPR | 7175 | 18 | -2.638 | 3.072 | 28 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
APLP2 | 334 | 12 | -2.732 | 3.206 | 35 | Yes | Yes |
[ DDX4 ] | 54514 | 1 | -1.245 | 2.806 | 13 | - | - |
ZFP36 | 7538 | 10 | -2.968 | 2.869 | 24 | Yes | Yes |
NFKB1 | 4790 | 9 | -2.123 | 2.870 | 263 | Yes | - |
HNRNPD | 3184 | 5 | -2.153 | 3.117 | 123 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
TPM1 | 7168 | 2 | -2.686 | 2.957 | 44 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
CARM1 | 10498 | 1 | -1.583 | 2.806 | 68 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
TPM1 | 7168 | DDX4 | 54514 | pp | -- | int.I2D: BioGrid_Fly |
NFRKB | 4798 | YY1 | 7528 | pp | -- | int.I2D: BioGrid |
EP300 | 2033 | NFKB1 | 4790 | pp | -- | int.I2D: BioGrid |
TPM1 | 7168 | LARS | 51520 | pp | -- | int.I2D: IntAct_Worm |
HNRNPD | 3184 | HNRNPU | 3192 | pp | -- | int.Mint: MI:0915(physical association) |
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
EP300 | 2033 | YY1 | 7528 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Transfac: -; int.Ravasi: -; int.HPRD: in vivo; int.DIP: MI:0218(physical interaction) |
DDIT3 | 1649 | NFKB1 | 4790 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
PSMD2 | 5708 | LARS | 51520 | pp | -- | int.I2D: BioGrid_Yeast |
NFKB1 | 4790 | CARM1 | 10498 | pp | -- | int.I2D: BioGrid |
NFKB1 | 4790 | YY1 | 7528 | pp | -- | int.Intact: MI:0915(physical association) |
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
EP300 | 2033 | HES6 | 55502 | pp | -- | int.I2D: IntAct |
NFKB1 | 4790 | NFRKB | 4798 | pp | -- | int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
DDIT3 | 1649 | HNRNPD | 3184 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
CARM1 | 10498 | DDX4 | 54514 | pp | -- | int.I2D: BioGrid_Fly |
EP300 | 2033 | CARM1 | 10498 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vivo |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
HNRNPD | 3184 | CARM1 | 10498 | pp | -- | int.I2D: BioGrid_Fly |
APLP2 | 334 | NFKB1 | 4790 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
NFKB1 | 4790 | TPR | 7175 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
NFKB1 | 4790 | ZFP36 | 7538 | pp | -- | int.I2D: BioGrid |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0044212 | transcription regulatory region DNA binding | 3.78e-08 | 5.45e-04 | 4.839 | 6 | 17 | 168 |
GO:0005654 | nucleoplasm | 1.36e-07 | 1.96e-03 | 2.889 | 10 | 64 | 1082 |
GO:0005634 | nucleus | 7.38e-07 | 1.07e-02 | 1.492 | 16 | 159 | 4559 |
GO:0003677 | DNA binding | 5.11e-06 | 7.37e-02 | 2.566 | 9 | 49 | 1218 |
GO:0008134 | transcription factor binding | 9.15e-06 | 1.32e-01 | 4.049 | 5 | 18 | 242 |
GO:0006355 | regulation of transcription, DNA-templated | 1.19e-05 | 1.71e-01 | 2.685 | 8 | 43 | 997 |
GO:0005667 | transcription factor complex | 5.61e-05 | 8.09e-01 | 4.195 | 4 | 17 | 175 |
GO:0010467 | gene expression | 1.12e-04 | 1.00e+00 | 2.845 | 6 | 45 | 669 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 1.14e-04 | 1.00e+00 | 6.946 | 2 | 2 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 1.14e-04 | 1.00e+00 | 6.946 | 2 | 2 | 13 |
GO:0031011 | Ino80 complex | 1.33e-04 | 1.00e+00 | 6.839 | 2 | 6 | 14 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.43e-04 | 1.00e+00 | 2.782 | 6 | 39 | 699 |
GO:0003713 | transcription coactivator activity | 1.81e-04 | 1.00e+00 | 3.757 | 4 | 24 | 237 |
GO:0005829 | cytosol | 2.68e-04 | 1.00e+00 | 1.683 | 10 | 86 | 2496 |
GO:0005515 | protein binding | 3.76e-04 | 1.00e+00 | 0.997 | 15 | 198 | 6024 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 5.29e-04 | 1.00e+00 | 2.813 | 5 | 37 | 570 |
GO:0042594 | response to starvation | 6.70e-04 | 1.00e+00 | 5.692 | 2 | 4 | 31 |
GO:0031072 | heat shock protein binding | 7.59e-04 | 1.00e+00 | 5.602 | 2 | 2 | 33 |
GO:0006974 | cellular response to DNA damage stimulus | 8.18e-04 | 1.00e+00 | 3.993 | 3 | 7 | 151 |
GO:0003065 | positive regulation of heart rate by epinephrine | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:1901673 | regulation of spindle assembly involved in mitosis | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060350 | endochondral bone morphogenesis | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0043578 | nuclear matrix organization | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0010965 | regulation of mitotic sister chromatid separation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0034971 | histone H3-R17 methylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0035642 | histone methyltransferase activity (H3-R17 specific) | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0045083 | negative regulation of interleukin-12 biosynthetic process | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0006404 | RNA import into nucleus | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0031453 | positive regulation of heterochromatin assembly | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0003714 | transcription corepressor activity | 1.32e-03 | 1.00e+00 | 3.755 | 3 | 11 | 178 |
GO:0045727 | positive regulation of translation | 1.35e-03 | 1.00e+00 | 5.187 | 2 | 2 | 44 |
GO:0050728 | negative regulation of inflammatory response | 2.18e-03 | 1.00e+00 | 4.839 | 2 | 3 | 56 |
GO:0006396 | RNA processing | 2.41e-03 | 1.00e+00 | 4.764 | 2 | 5 | 59 |
GO:0006429 | leucyl-tRNA aminoacylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0031990 | mRNA export from nucleus in response to heat stress | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0006403 | RNA localization | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0070840 | dynein complex binding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0009405 | pathogenesis | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0046832 | negative regulation of RNA export from nucleus | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0034696 | response to prostaglandin F | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0000189 | MAPK import into nucleus | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0034970 | histone H3-R2 methylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0008013 | beta-catenin binding | 2.49e-03 | 1.00e+00 | 4.739 | 2 | 9 | 60 |
GO:0035984 | cellular response to trichostatin A | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0004823 | leucine-tRNA ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0016071 | mRNA metabolic process | 2.51e-03 | 1.00e+00 | 3.430 | 3 | 8 | 223 |
GO:0032481 | positive regulation of type I interferon production | 2.58e-03 | 1.00e+00 | 4.715 | 2 | 6 | 61 |
GO:0016070 | RNA metabolic process | 3.35e-03 | 1.00e+00 | 3.283 | 3 | 8 | 247 |
GO:0003729 | mRNA binding | 3.57e-03 | 1.00e+00 | 4.476 | 2 | 4 | 72 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0046914 | transition metal ion binding | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0042306 | regulation of protein import into nucleus | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 3 |
GO:0060913 | cardiac cell fate determination | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:1900127 | positive regulation of hyaluronan biosynthetic process | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0050779 | RNA destabilization | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0033146 | regulation of intracellular estrogen receptor signaling pathway | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0033256 | I-kappaB/NF-kappaB complex | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0006405 | RNA export from nucleus | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0016032 | viral process | 3.76e-03 | 1.00e+00 | 2.585 | 4 | 26 | 534 |
GO:0032680 | regulation of tumor necrosis factor production | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0032375 | negative regulation of cholesterol transport | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0097157 | pre-mRNA intronic binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0016274 | protein-arginine N-methyltransferase activity | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0071547 | piP-body | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0010957 | negative regulation of vitamin D biosynthetic process | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0097167 | circadian regulation of translation | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0032269 | negative regulation of cellular protein metabolic process | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:2000630 | positive regulation of miRNA metabolic process | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0006999 | nuclear pore organization | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0005862 | muscle thin filament tropomyosin | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0044615 | nuclear pore nuclear basket | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0001714 | endodermal cell fate specification | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0019957 | C-C chemokine binding | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 2 | 5 |
GO:0010884 | positive regulation of lipid storage | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0035925 | mRNA 3'-UTR AU-rich region binding | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0071546 | pi-body | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0008276 | protein methyltransferase activity | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0010793 | regulation of mRNA export from nucleus | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0070849 | response to epidermal growth factor | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0007176 | regulation of epidermal growth factor-activated receptor activity | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 3 | 6 |
GO:0008469 | histone-arginine N-methyltransferase activity | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0044822 | poly(A) RNA binding | 7.99e-03 | 1.00e+00 | 1.924 | 5 | 50 | 1056 |
GO:0003723 | RNA binding | 8.28e-03 | 1.00e+00 | 2.813 | 3 | 18 | 342 |
GO:0030529 | ribonucleoprotein complex | 8.43e-03 | 1.00e+00 | 3.839 | 2 | 5 | 112 |
GO:0046825 | regulation of protein export from nucleus | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0071354 | cellular response to interleukin-6 | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0032059 | bleb | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0006475 | internal protein amino acid acetylation | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0042054 | histone methyltransferase activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 3 | 8 |
GO:0051292 | nuclear pore complex assembly | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 4 | 8 |
GO:0007617 | mating behavior | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0001955 | blood vessel maturation | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0071316 | cellular response to nicotine | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0035457 | cellular response to interferon-alpha | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0042405 | nuclear inclusion body | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0006450 | regulation of translational fidelity | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0035259 | glucocorticoid receptor binding | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0000975 | regulatory region DNA binding | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0045793 | positive regulation of cell size | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0035278 | negative regulation of translation involved in gene silencing by miRNA | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0043495 | protein anchor | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0000400 | four-way junction DNA binding | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0000278 | mitotic cell cycle | 1.19e-02 | 1.00e+00 | 2.620 | 3 | 15 | 391 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 10 |
GO:0035413 | positive regulation of catenin import into nucleus | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 10 |
GO:0045662 | negative regulation of myoblast differentiation | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 3 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 2 | 11 |
GO:0043923 | positive regulation by host of viral transcription | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 3 | 11 |
GO:0042162 | telomeric DNA binding | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 11 |
GO:0033391 | chromatoid body | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 4 | 11 |
GO:0006366 | transcription from RNA polymerase II promoter | 1.44e-02 | 1.00e+00 | 2.520 | 3 | 30 | 419 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.47e-02 | 1.00e+00 | 2.022 | 4 | 41 | 789 |
GO:0006878 | cellular copper ion homeostasis | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0006402 | mRNA catabolic process | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0045947 | negative regulation of translational initiation | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 2 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 3 | 12 |
GO:0034399 | nuclear periphery | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 5 | 12 |
GO:0005838 | proteasome regulatory particle | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0046688 | response to copper ion | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0006937 | regulation of muscle contraction | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0043488 | regulation of mRNA stability | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0005868 | cytoplasmic dynein complex | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 13 |
GO:0046827 | positive regulation of protein export from nucleus | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0001967 | suckling behavior | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0031293 | membrane protein intracellular domain proteolysis | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0017091 | AU-rich element binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 14 |
GO:0070542 | response to fatty acid | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0034614 | cellular response to reactive oxygen species | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 14 |
GO:0006401 | RNA catabolic process | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0071375 | cellular response to peptide hormone stimulus | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 14 |
GO:0032993 | protein-DNA complex | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 14 |
GO:0005487 | nucleocytoplasmic transporter activity | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 3 | 14 |
GO:0000398 | mRNA splicing, via spliceosome | 1.74e-02 | 1.00e+00 | 3.289 | 2 | 15 | 164 |
GO:0042307 | positive regulation of protein import into nucleus | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 4 | 15 |
GO:0016571 | histone methylation | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 15 |
GO:0031529 | ruffle organization | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0001824 | blastocyst development | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0042176 | regulation of protein catabolic process | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 16 |
GO:0007141 | male meiosis I | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0051276 | chromosome organization | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 16 |
GO:0045638 | negative regulation of myeloid cell differentiation | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0045893 | positive regulation of transcription, DNA-templated | 2.04e-02 | 1.00e+00 | 2.330 | 3 | 24 | 478 |
GO:0090316 | positive regulation of intracellular protein transport | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 2 | 17 |
GO:0022624 | proteasome accessory complex | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 17 |
GO:0070577 | lysine-acetylated histone binding | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 17 |
GO:0071889 | 14-3-3 protein binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 18 |
GO:0030520 | intracellular estrogen receptor signaling pathway | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 18 |
GO:0045773 | positive regulation of axon extension | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 18 |
GO:0035257 | nuclear hormone receptor binding | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 20 |
GO:0043393 | regulation of protein binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 20 |
GO:0005737 | cytoplasm | 2.55e-02 | 1.00e+00 | 0.937 | 9 | 124 | 3767 |
GO:0032967 | positive regulation of collagen biosynthetic process | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 21 |
GO:0000123 | histone acetyltransferase complex | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 6 | 21 |
GO:0003823 | antigen binding | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 22 |
GO:0031941 | filamentous actin | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 22 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0006351 | transcription, DNA-templated | 2.84e-02 | 1.00e+00 | 1.470 | 5 | 57 | 1446 |
GO:0032781 | positive regulation of ATPase activity | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 1 | 24 |
GO:0043388 | positive regulation of DNA binding | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 2 | 24 |
GO:0055010 | ventricular cardiac muscle tissue morphogenesis | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 1 | 24 |
GO:0043425 | bHLH transcription factor binding | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 1 | 24 |
GO:0006915 | apoptotic process | 3.01e-02 | 1.00e+00 | 2.115 | 3 | 12 | 555 |
GO:0006611 | protein export from nucleus | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 3 | 25 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 3 | 25 |
GO:0031519 | PcG protein complex | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 25 |
GO:0051059 | NF-kappaB binding | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 3 | 25 |
GO:0035329 | hippo signaling | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 5 | 26 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 26 |
GO:0045214 | sarcomere organization | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 26 |
GO:0008380 | RNA splicing | 3.22e-02 | 1.00e+00 | 2.813 | 2 | 22 | 228 |
GO:0007399 | nervous system development | 3.30e-02 | 1.00e+00 | 2.794 | 2 | 6 | 231 |
GO:0015631 | tubulin binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 27 |
GO:0034612 | response to tumor necrosis factor | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 1 | 27 |
GO:0003727 | single-stranded RNA binding | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 28 |
GO:0050714 | positive regulation of protein secretion | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 3 | 28 |
GO:0034605 | cellular response to heat | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 28 |
GO:0030901 | midbrain development | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 1 | 29 |
GO:0072686 | mitotic spindle | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 3 | 29 |
GO:0042803 | protein homodimerization activity | 3.59e-02 | 1.00e+00 | 2.014 | 3 | 19 | 595 |
GO:0006606 | protein import into nucleus | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 2 | 30 |
GO:0031647 | regulation of protein stability | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 4 | 30 |
GO:0010827 | regulation of glucose transport | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 4 | 30 |
GO:0034644 | cellular response to UV | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 30 |
GO:0008016 | regulation of heart contraction | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 30 |
GO:0010494 | cytoplasmic stress granule | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 2 | 30 |
GO:0007094 | mitotic spindle assembly checkpoint | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 3 | 31 |
GO:0071347 | cellular response to interleukin-1 | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 2 | 31 |
GO:0032091 | negative regulation of protein binding | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 3 | 32 |
GO:0043491 | protein kinase B signaling | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:0045600 | positive regulation of fat cell differentiation | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:0001756 | somitogenesis | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 1 | 33 |
GO:0071333 | cellular response to glucose stimulus | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 1 | 33 |
GO:0030317 | sperm motility | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 1 | 33 |
GO:0007283 | spermatogenesis | 4.15e-02 | 1.00e+00 | 2.613 | 2 | 3 | 262 |
GO:0030017 | sarcomere | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 2 | 34 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 4.21e-02 | 1.00e+00 | 2.602 | 2 | 23 | 264 |
GO:0007077 | mitotic nuclear envelope disassembly | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 4 | 36 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 1 | 36 |
GO:0032880 | regulation of protein localization | 4.52e-02 | 1.00e+00 | 4.437 | 1 | 2 | 37 |
GO:0042752 | regulation of circadian rhythm | 4.52e-02 | 1.00e+00 | 4.437 | 1 | 3 | 37 |
GO:0006954 | inflammatory response | 4.59e-02 | 1.00e+00 | 2.532 | 2 | 6 | 277 |
GO:0030049 | muscle filament sliding | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 3 | 38 |
GO:0031490 | chromatin DNA binding | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 2 | 38 |
GO:0051496 | positive regulation of stress fiber assembly | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 4 | 38 |
GO:0032092 | positive regulation of protein binding | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 1 | 38 |
GO:0008645 | hexose transport | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 4 | 39 |
GO:0008026 | ATP-dependent helicase activity | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 1 | 39 |
GO:0060048 | cardiac muscle contraction | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 1 | 39 |
GO:0045785 | positive regulation of cell adhesion | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 2 | 40 |
GO:0046332 | SMAD binding | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 1 | 40 |
GO:0035019 | somatic stem cell maintenance | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 6 | 40 |
GO:0050885 | neuromuscular process controlling balance | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 2 | 40 |
GO:0007519 | skeletal muscle tissue development | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 2 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 5.00e-02 | 1.00e+00 | 4.289 | 1 | 2 | 41 |
GO:0008307 | structural constituent of muscle | 5.00e-02 | 1.00e+00 | 4.289 | 1 | 2 | 41 |
GO:0006418 | tRNA aminoacylation for protein translation | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 3 | 42 |
GO:0019898 | extrinsic component of membrane | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 2 | 42 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 7 | 43 |
GO:0004402 | histone acetyltransferase activity | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 6 | 43 |
GO:0030154 | cell differentiation | 5.33e-02 | 1.00e+00 | 2.413 | 2 | 5 | 301 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 4 | 44 |
GO:0003712 | transcription cofactor activity | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 8 | 44 |
GO:0051591 | response to cAMP | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 4 | 45 |
GO:0043966 | histone H3 acetylation | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 5 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 5.59e-02 | 1.00e+00 | 4.123 | 1 | 4 | 46 |
GO:0008092 | cytoskeletal protein binding | 5.71e-02 | 1.00e+00 | 4.092 | 1 | 1 | 47 |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 48 |
GO:0030900 | forebrain development | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 1 | 49 |
GO:0035690 | cellular response to drug | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 3 | 49 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 1 | 50 |
GO:0006986 | response to unfolded protein | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 4 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 1 | 51 |
GO:0003682 | chromatin binding | 6.18e-02 | 1.00e+00 | 2.293 | 2 | 19 | 327 |
GO:0009611 | response to wounding | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 4 | 53 |
GO:0051592 | response to calcium ion | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 1 | 55 |
GO:0002039 | p53 binding | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 4 | 55 |
GO:0015758 | glucose transport | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 4 | 55 |
GO:0001725 | stress fiber | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 4 | 55 |
GO:0071300 | cellular response to retinoic acid | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 1 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 2 | 55 |
GO:0043627 | response to estrogen | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 5 | 56 |
GO:0043565 | sequence-specific DNA binding | 6.82e-02 | 1.00e+00 | 2.212 | 2 | 11 | 346 |
GO:0008203 | cholesterol metabolic process | 6.88e-02 | 1.00e+00 | 3.813 | 1 | 2 | 57 |
GO:0005643 | nuclear pore | 6.88e-02 | 1.00e+00 | 3.813 | 1 | 11 | 57 |
GO:0000502 | proteasome complex | 7.00e-02 | 1.00e+00 | 3.788 | 1 | 3 | 58 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 7.12e-02 | 1.00e+00 | 3.764 | 1 | 6 | 59 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 7.12e-02 | 1.00e+00 | 3.764 | 1 | 5 | 59 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 7.35e-02 | 1.00e+00 | 3.715 | 1 | 2 | 61 |
GO:0004867 | serine-type endopeptidase inhibitor activity | 7.58e-02 | 1.00e+00 | 3.669 | 1 | 3 | 63 |
GO:0000776 | kinetochore | 7.58e-02 | 1.00e+00 | 3.669 | 1 | 5 | 63 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 7.58e-02 | 1.00e+00 | 3.669 | 1 | 4 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 7.70e-02 | 1.00e+00 | 3.646 | 1 | 1 | 64 |
GO:0042060 | wound healing | 7.70e-02 | 1.00e+00 | 3.646 | 1 | 2 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 2 | 65 |
GO:0006310 | DNA recombination | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 7 | 65 |
GO:0071260 | cellular response to mechanical stimulus | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 4 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 4 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 4 | 65 |
GO:0010468 | regulation of gene expression | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 2 | 68 |
GO:0032587 | ruffle membrane | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 3 | 70 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 70 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 8.50e-02 | 1.00e+00 | 3.496 | 1 | 4 | 71 |
GO:0007626 | locomotory behavior | 8.50e-02 | 1.00e+00 | 3.496 | 1 | 2 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 8.50e-02 | 1.00e+00 | 3.496 | 1 | 4 | 71 |
GO:0034162 | toll-like receptor 9 signaling pathway | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 4 | 72 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 1 | 72 |
GO:0030324 | lung development | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 1 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 8.73e-02 | 1.00e+00 | 3.456 | 1 | 4 | 73 |
GO:0000785 | chromatin | 8.73e-02 | 1.00e+00 | 3.456 | 1 | 6 | 73 |
GO:0002020 | protease binding | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 6 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 2 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 1 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 1 | 75 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 9.08e-02 | 1.00e+00 | 3.398 | 1 | 3 | 76 |
GO:0001889 | liver development | 9.19e-02 | 1.00e+00 | 3.379 | 1 | 3 | 77 |
GO:0030336 | negative regulation of cell migration | 9.30e-02 | 1.00e+00 | 3.361 | 1 | 1 | 78 |
GO:0071013 | catalytic step 2 spliceosome | 9.30e-02 | 1.00e+00 | 3.361 | 1 | 7 | 78 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 9.30e-02 | 1.00e+00 | 3.361 | 1 | 3 | 78 |
GO:0034138 | toll-like receptor 3 signaling pathway | 9.42e-02 | 1.00e+00 | 3.342 | 1 | 3 | 79 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 9.42e-02 | 1.00e+00 | 3.342 | 1 | 2 | 79 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 9.42e-02 | 1.00e+00 | 3.342 | 1 | 2 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 5 | 80 |
GO:0071222 | cellular response to lipopolysaccharide | 9.65e-02 | 1.00e+00 | 3.306 | 1 | 4 | 81 |
GO:0043066 | negative regulation of apoptotic process | 9.68e-02 | 1.00e+00 | 1.918 | 2 | 16 | 424 |
GO:0009653 | anatomical structure morphogenesis | 9.87e-02 | 1.00e+00 | 3.271 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 9.87e-02 | 1.00e+00 | 3.271 | 1 | 4 | 83 |
GO:0050852 | T cell receptor signaling pathway | 1.01e-01 | 1.00e+00 | 3.237 | 1 | 2 | 85 |
GO:0009887 | organ morphogenesis | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 5 | 86 |
GO:0003690 | double-stranded DNA binding | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 3 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 3 | 86 |
GO:0006979 | response to oxidative stress | 1.03e-01 | 1.00e+00 | 3.203 | 1 | 6 | 87 |
GO:0006936 | muscle contraction | 1.03e-01 | 1.00e+00 | 3.203 | 1 | 3 | 87 |
GO:0016363 | nuclear matrix | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 6 | 91 |
GO:0007010 | cytoskeleton organization | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 4 | 91 |
GO:0006928 | cellular component movement | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 3 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 6 | 91 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 1 | 92 |
GO:0001649 | osteoblast differentiation | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 7 | 92 |
GO:0005770 | late endosome | 1.10e-01 | 1.00e+00 | 3.107 | 1 | 2 | 93 |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 4 | 96 |
GO:0051726 | regulation of cell cycle | 1.14e-01 | 1.00e+00 | 3.046 | 1 | 5 | 97 |
GO:0001934 | positive regulation of protein phosphorylation | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 5 | 104 |
GO:0010951 | negative regulation of endopeptidase activity | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 6 | 104 |
GO:0003676 | nucleic acid binding | 1.26e-01 | 1.00e+00 | 2.905 | 1 | 2 | 107 |
GO:0002224 | toll-like receptor signaling pathway | 1.28e-01 | 1.00e+00 | 2.878 | 1 | 4 | 109 |
GO:0005635 | nuclear envelope | 1.32e-01 | 1.00e+00 | 2.826 | 1 | 5 | 113 |
GO:0000209 | protein polyubiquitination | 1.35e-01 | 1.00e+00 | 2.788 | 1 | 3 | 116 |
GO:0046983 | protein dimerization activity | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 5 | 118 |
GO:0006325 | chromatin organization | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 12 | 118 |
GO:0005730 | nucleolus | 1.40e-01 | 1.00e+00 | 0.966 | 4 | 66 | 1641 |
GO:0007219 | Notch signaling pathway | 1.40e-01 | 1.00e+00 | 2.739 | 1 | 5 | 120 |
GO:0008201 | heparin binding | 1.42e-01 | 1.00e+00 | 2.715 | 1 | 1 | 122 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.44e-01 | 1.00e+00 | 2.692 | 1 | 5 | 124 |
GO:0007050 | cell cycle arrest | 1.44e-01 | 1.00e+00 | 2.692 | 1 | 5 | 124 |
GO:0005215 | transporter activity | 1.50e-01 | 1.00e+00 | 2.624 | 1 | 3 | 130 |
GO:0044255 | cellular lipid metabolic process | 1.54e-01 | 1.00e+00 | 2.591 | 1 | 2 | 133 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.57e-01 | 1.00e+00 | 2.559 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 1.59e-01 | 1.00e+00 | 2.538 | 1 | 4 | 138 |
GO:0007507 | heart development | 1.60e-01 | 1.00e+00 | 2.527 | 1 | 7 | 139 |
GO:0045087 | innate immune response | 1.69e-01 | 1.00e+00 | 1.427 | 2 | 15 | 596 |
GO:0001666 | response to hypoxia | 1.71e-01 | 1.00e+00 | 2.427 | 1 | 7 | 149 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.71e-01 | 1.00e+00 | 2.427 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 1.72e-01 | 1.00e+00 | 2.417 | 1 | 4 | 150 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.87e-01 | 1.00e+00 | 2.280 | 1 | 12 | 165 |
GO:0044281 | small molecule metabolic process | 1.88e-01 | 1.00e+00 | 0.989 | 3 | 20 | 1211 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 5 | 168 |
GO:0031965 | nuclear membrane | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 10 | 168 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.93e-01 | 1.00e+00 | 2.228 | 1 | 2 | 171 |
GO:0031625 | ubiquitin protein ligase binding | 2.00e-01 | 1.00e+00 | 2.170 | 1 | 5 | 178 |
GO:0032403 | protein complex binding | 2.05e-01 | 1.00e+00 | 2.130 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 2.06e-01 | 1.00e+00 | 2.123 | 1 | 22 | 184 |
GO:0005524 | ATP binding | 2.17e-01 | 1.00e+00 | 0.889 | 3 | 31 | 1298 |
GO:0001701 | in utero embryonic development | 2.23e-01 | 1.00e+00 | 1.995 | 1 | 8 | 201 |
GO:0019221 | cytokine-mediated signaling pathway | 2.43e-01 | 1.00e+00 | 1.858 | 1 | 8 | 221 |
GO:0007067 | mitotic nuclear division | 2.49e-01 | 1.00e+00 | 1.820 | 1 | 6 | 227 |
GO:0005975 | carbohydrate metabolic process | 2.73e-01 | 1.00e+00 | 1.663 | 1 | 8 | 253 |
GO:0000166 | nucleotide binding | 2.78e-01 | 1.00e+00 | 1.629 | 1 | 13 | 259 |
GO:0006281 | DNA repair | 2.80e-01 | 1.00e+00 | 1.618 | 1 | 14 | 261 |
GO:0003779 | actin binding | 2.85e-01 | 1.00e+00 | 1.591 | 1 | 10 | 266 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.88e-01 | 1.00e+00 | 1.575 | 1 | 7 | 269 |
GO:0030198 | extracellular matrix organization | 3.00e-01 | 1.00e+00 | 1.502 | 1 | 6 | 283 |
GO:0007186 | G-protein coupled receptor signaling pathway | 3.05e-01 | 1.00e+00 | 1.471 | 1 | 1 | 289 |
GO:0005856 | cytoskeleton | 3.07e-01 | 1.00e+00 | 1.461 | 1 | 9 | 291 |
GO:0006200 | ATP catabolic process | 3.08e-01 | 1.00e+00 | 1.456 | 1 | 2 | 292 |
GO:0035556 | intracellular signal transduction | 3.18e-01 | 1.00e+00 | 1.403 | 1 | 9 | 303 |
GO:0007275 | multicellular organismal development | 3.29e-01 | 1.00e+00 | 1.342 | 1 | 7 | 316 |
GO:0019901 | protein kinase binding | 3.30e-01 | 1.00e+00 | 1.338 | 1 | 18 | 317 |
GO:0008283 | cell proliferation | 3.39e-01 | 1.00e+00 | 1.289 | 1 | 14 | 328 |
GO:0016020 | membrane | 3.51e-01 | 1.00e+00 | 0.516 | 3 | 46 | 1681 |
GO:0008270 | zinc ion binding | 3.56e-01 | 1.00e+00 | 0.685 | 2 | 27 | 997 |
GO:0046982 | protein heterodimerization activity | 3.82e-01 | 1.00e+00 | 1.076 | 1 | 8 | 380 |
GO:0008284 | positive regulation of cell proliferation | 3.83e-01 | 1.00e+00 | 1.069 | 1 | 10 | 382 |
GO:0009986 | cell surface | 3.99e-01 | 1.00e+00 | 0.995 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 4.07e-01 | 1.00e+00 | 0.956 | 1 | 24 | 413 |
GO:0055085 | transmembrane transport | 4.24e-01 | 1.00e+00 | 0.881 | 1 | 8 | 435 |
GO:0044267 | cellular protein metabolic process | 4.52e-01 | 1.00e+00 | 0.757 | 1 | 20 | 474 |
GO:0042802 | identical protein binding | 4.59e-01 | 1.00e+00 | 0.727 | 1 | 19 | 484 |
GO:0048471 | perinuclear region of cytoplasm | 4.72e-01 | 1.00e+00 | 0.675 | 1 | 8 | 502 |
GO:0070062 | extracellular vesicular exosome | 5.96e-01 | 1.00e+00 | 0.002 | 3 | 57 | 2400 |
GO:0005739 | mitochondrion | 7.25e-01 | 1.00e+00 | -0.317 | 1 | 23 | 998 |
GO:0046872 | metal ion binding | 8.19e-01 | 1.00e+00 | -0.706 | 1 | 29 | 1307 |
GO:0016021 | integral component of membrane | 9.30e-01 | 1.00e+00 | -1.307 | 1 | 17 | 1982 |
GO:0005886 | plasma membrane | 9.71e-01 | 1.00e+00 | -1.688 | 1 | 49 | 2582 |