meta-reg-snw-5905

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-5702 wolf-screen-ratio-mammosphere-adherent 0.969 7.65e-17 1.16e-03 2.31e-02 17 16
reg-snw-5905 wolf-screen-ratio-mammosphere-adherent 0.816 1.47e-06 3.71e-03 6.88e-03 6 6
int-snw-51477 wolf-screen-ratio-mammosphere-adherent 0.934 1.79e-15 2.53e-03 4.07e-02 9 8
int-snw-2064 wolf-screen-ratio-mammosphere-adherent 0.950 4.36e-16 1.79e-03 3.17e-02 15 15
int-snw-5216 wolf-screen-ratio-mammosphere-adherent 1.002 3.25e-18 5.25e-04 1.26e-02 12 11
int-snw-8317 wolf-screen-ratio-mammosphere-adherent 0.925 3.70e-15 3.01e-03 4.62e-02 17 16
int-snw-445 wolf-screen-ratio-mammosphere-adherent 0.946 6.14e-16 1.95e-03 3.37e-02 16 15
int-snw-1120 wolf-screen-ratio-mammosphere-adherent 0.934 1.80e-15 2.53e-03 4.08e-02 16 15
int-snw-5743 wolf-screen-ratio-mammosphere-adherent 0.944 7.33e-16 2.03e-03 3.48e-02 12 11
int-snw-6446 wolf-screen-ratio-mammosphere-adherent 0.930 2.55e-15 2.75e-03 4.33e-02 18 18
int-snw-10056 wolf-screen-ratio-mammosphere-adherent 0.958 2.11e-16 1.50e-03 2.78e-02 19 17
wolf-screen-ratio-mammosphere-adherent-meta-reg-snw-5905 subnetwork

Genes (52)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
TP53 7157 230.4320.833665--
ERBB2 2064 100.0040.950156Yes-
ASS1 445 17-0.1370.94649--
VARS 7407 860.5491.002204Yes-
CHKB 1120 12-0.1690.93442-Yes
ISYNA1 51477 3-0.1200.93448--
ATP6V1B2 526 530.8811.076278--
RPL11 6135 210.7181.017200Yes-
RPA2 6118 961.2501.15176Yes-
PSMA6 5687 190.6910.956137Yes-
PSMD1 5707 860.8360.830118Yes-
EIF2S2 8894 391.0750.940103Yes-
EEF2 1938 640.8901.043301Yes-
CDC7 8317 70.0420.92593--
RPS11 6205 620.9931.113175Yes-
MCM5 4174 230.5780.830273Yes-
PFN1 5216 10-0.1431.00278--
EFTUD2 9343 930.8830.956108Yes-
SGK1 6446 17-0.1890.93076-Yes
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
FARSB 10056 100.0990.95831--
HSPD1 3329 700.9131.035325Yes-
KPNB1 3837 170.6131.017296Yes-
ITK 3702 150.6020.95039Yes-
RBX1 9978 1151.1850.934148Yes-
POLA1 5422 170.5930.894114Yes-
PSMC3 5702 510.7191.002276Yes-
PSMB7 5695 1180.9820.93490Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMA1 5682 1000.9960.878152Yes-
RANGAP1 5905 11-0.0460.81674Yes-
DLST 1743 220.6461.026135Yes-
RPSA 3921 1201.3271.151152Yes-
RPS3A 6189 400.8351.069166Yes-
PGD 5226 891.2011.106152Yes-
ACO2 50 651.0001.076191Yes-
PTGS2 5743 11-0.2420.94414-Yes
CDC16 8881 530.9501.02080Yes-
PSMD13 5719 560.8480.801114Yes-
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
RPL14 9045 491.2501.113166Yes-
PSMB2 5690 1160.8770.956169Yes-
GSK3B 2932 220.4750.934319-Yes
ACTB 60 1341.1531.151610Yes-
SAP18 10284 201.1151.06957Yes-
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-
PSMC1 5700 510.8401.018137Yes-

Interactions (238)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
RPS11 6205 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
SGK1 6446 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMC3 5702 pp -- int.I2D: YeastLow, BioGrid_Yeast
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMA2 5683 PSMD13 5719 pp -- int.I2D: YeastLow
RPL11 6135 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
PSMA6 5687 RBX1 9978 pp -- int.I2D: BioGrid
PSMA6 5687 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
GSK3B 2932 TP53 7157 pp -- int.I2D: BIND, MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association), MI:0217(phosphorylation reaction);
int.HPRD: in vitro, in vivo
EEF2 1938 ISYNA1 51477 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Tarassov_PCA, IntAct_Yeast
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
ACTB 60 RPL11 6135 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMC3 5702 VARS 7407 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
KPNB1 3837 TP53 7157 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vivo
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
PFN1 5216 TP53 7157 pd < reg.ITFP.txt: no annot
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
ACTB 60 KPNB1 3837 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMD1 5707 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMD1 5707 CDC7 8317 pp -- int.I2D: IntAct_Yeast
PSMC1 5700 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PSMC3 5702 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
GSK3B 2932 SGK1 6446 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro, in vivo
PSMC3 5702 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB7 5695 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PTGS2 5743 TP53 7157 pp -- int.I2D: BioGrid, BIND, HPRD;
int.HPRD: in vivo
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
MCM5 4174 EFTUD2 9343 pd > reg.ITFP.txt: no annot
ASS1 445 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
RPA2 6118 TP53 7157 pp -- int.Transfac: -
TP53 7157 EIF2S2 8894 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
RPS3A 6189 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMC3 5702 PSMD3 5709 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ASS1 445 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMC3 5702 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 TP53 7157 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
GSK3B 2932 TUBG1 7283 pp -- int.I2D: MINT
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
POLA1 5422 CDC7 8317 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RPS3A 6189 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA6 5687 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, HPRD, Krogan_Core, Tarassov_PCA, Yu_GoldStd;
int.HPRD: yeast 2-hybrid
ATP6V1B2 526 CHKB 1120 pp -- int.I2D: IntAct_Yeast
EEF2 1938 TP53 7157 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CHKB 1120 PSMD3 5709 pp -- int.I2D: IntAct_Yeast
CHKB 1120 GSK3B 2932 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
SGK1 6446 VARS 7407 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPSA 3921 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 SAP18 10284 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
DLST 1743 RPSA 3921 pp -- int.I2D: IntAct_Yeast
DLST 1743 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
RPS3A 6189 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ASS1 445 RPL11 6135 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
PSMA6 5687 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMC3 5702 CDC7 8317 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMC3 5702 TP53 7157 pp -- int.I2D: BioGrid
ACTB 60 ERBB2 2064 pp -- int.Intact: MI:0915(physical association), MI:0403(colocalization), MI:0914(association)
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMA2 5683 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACO2 50 RANGAP1 5905 pp -- int.I2D: YeastLow
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 CDC7 8317 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMA6 5687 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, CE_DATA, IntAct, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid_Worm, HPRD, Krogan_Core, MINT, StelzlHigh, Tarassov_PCA;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
PSMC3 5702 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
KPNB1 3837 PSMA2 5683 pp -- int.I2D: Krogan_NonCore, YeastLow
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ASS1 445 DLST 1743 pp -- int.I2D: YeastLow
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
HNRNPC 3183 TP53 7157 pd < reg.ITFP.txt: no annot
DLST 1743 RPL11 6135 pp -- int.I2D: BioGrid_Yeast
MCM5 4174 RPA2 6118 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: yeast 2-hybrid
PSMC3 5702 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
RPL11 6135 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD1 5707 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, Krogan_Core, MINT_Yeast
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
DLST 1743 HSPD1 3329 pp -- int.I2D: IntAct_Yeast, YeastLow
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CLTC 1213 PFN1 5216 pp -- int.I2D: BioGrid_Mouse
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
DLST 1743 PSMA3 5684 pp -- int.I2D: YeastLow
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
ACO2 50 PSMC1 5700 pp -- int.I2D: YeastLow
PSMC1 5700 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD13 5719 RUVBL2 10856 pp -- int.I2D: YeastHigh
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
PSMA6 5687 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
MCM5 4174 CDC7 8317 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Mouse, HPRD;
int.HPRD: yeast 2-hybrid
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
CLTC 1213 KPNB1 3837 pp -- int.Intact: MI:0914(association)
ACO2 50 KPNB1 3837 pp -- int.I2D: IntAct_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
POLA1 5422 TP53 7157 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vivo
PTGS2 5743 RBX1 9978 pp -- int.I2D: BioGrid
PSMC3 5702 RPL11 6135 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 TP53 7157 pp -- int.Intact: MI:0914(association)
ASS1 445 PSMA3 5684 pp -- int.I2D: YeastLow
PSMD3 5709 RANGAP1 5905 pd > reg.ITFP.txt: no annot
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ERBB2 2064 KPNB1 3837 pp -- int.Intact: MI:0915(physical association), MI:0914(association), MI:0403(colocalization)
PSMC3 5702 FARSB 10056 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMA6 5687 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC3 5702 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 PSMA6 5687 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, YeastHigh, IntAct_Worm, Krogan_Core, MINT_Yeast;
int.Mint: MI:0914(association)
PSMA1 5682 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACO2 50 ISYNA1 51477 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
PSMA6 5687 SGK1 6446 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMC3 5702 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMC3 5702 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
PSMC1 5700 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
MCM5 4174 PSMD13 5719 pp -- int.I2D: YeastLow
DLST 1743 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMA6 5687 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG, Yu_GoldStd
ACTB 60 PFN1 5216 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Mouse, HPRD, MINT_Mouse, BCI, IntAct;
int.HPRD: in vitro;
int.DIP: MI:0407(direct interaction)
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
PSMA3 5684 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastLow
KPNB1 3837 PSMA1 5682 pp -- int.I2D: YeastLow
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
ACTB 60 FARSB 10056 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD1 5707 PTGS2 5743 pp -- int.I2D: BioGrid, INNATEDB
RPL11 6135 TP53 7157 pp -- int.I2D: BioGrid
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 PSMD13 5719 pd < reg.ITFP.txt: no annot
KPNB1 3837 RANGAP1 5905 pp -- int.I2D: BioGrid_Yeast, YeastLow
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RANGAP1 5905 VARS 7407 pd < reg.ITFP.txt: no annot
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMC1 5700 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
KPNB1 3837 PSMA3 5684 pp -- int.I2D: YeastLow
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPL11 6135 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 SGK1 6446 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA6 5687 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastLow
KPNB1 3837 PSMC3 5702 pp -- int.I2D: YeastLow
GSK3B 2932 EFTUD2 9343 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ERBB2 2064 ITK 3702 pp -- int.I2D: JonesErbB1, MINT;
int.Mint: MI:0407(direct interaction)
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ATP6V1B2 526 DLST 1743 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
KPNB1 3837 PSMA6 5687 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA6 5687 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMA1 5682 PSMC1 5700 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
PSMA6 5687 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastLow
VARS 7407 FARSB 10056 pp -- int.I2D: Krogan_NonCore
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
HSPD1 3329 POLA1 5422 pp -- int.I2D: YeastLow
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
CLTC 1213 ISYNA1 51477 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Tarassov_PCA, IntAct_Yeast
KPNB1 3837 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
PSMA6 5687 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow, BioGrid
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
ATP6V1B2 526 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 MCM5 4174 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
KPNB1 3837 RUVBL2 10856 pp -- int.I2D: BioGrid
ATP6V1B2 526 MCM5 4174 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
PSMB2 5690 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA6 5687 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
PSMC3 5702 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
CLTC 1213 ERBB2 2064 pp -- int.Intact: MI:0914(association)

Related GO terms (760)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005829cytosol8.12e-241.33e-192.328411252562
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest8.89e-231.45e-186.079142265
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.89e-231.45e-186.079142465
GO:0000082G1/S transition of mitotic cell cycle1.57e-222.56e-185.1531733150
GO:0006521regulation of cellular amino acid metabolic process2.23e-223.63e-186.351132150
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.79e-224.55e-185.972142470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.52e-221.06e-175.892142474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.76e-212.87e-175.798142579
GO:0000502proteasome complex1.95e-213.18e-176.136132258
GO:0016071mRNA metabolic process3.90e-216.37e-174.6631834223
GO:0016032viral process8.15e-211.33e-163.7412355540
GO:0016070RNA metabolic process2.51e-204.10e-164.5161834247
GO:0010467gene expression4.89e-207.98e-163.4932458669
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent5.14e-208.40e-165.805132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.09e-191.77e-155.728132377
GO:0000278mitotic cell cycle2.12e-193.46e-153.9792052398
GO:0042981regulation of apoptotic process5.12e-198.36e-154.9621526151
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.71e-182.80e-145.440132394
GO:0034641cellular nitrogen compound metabolic process5.85e-189.55e-144.7331525177
GO:0000209protein polyubiquitination2.98e-174.86e-135.1361321116
GO:0005654nucleoplasm2.95e-164.81e-122.84125831095
GO:0043066negative regulation of apoptotic process1.10e-141.79e-103.6231730433
GO:0022624proteasome accessory complex4.15e-146.78e-107.0147917
GO:0006915apoptotic process1.32e-112.15e-073.1371634571
GO:0005839proteasome core complex1.40e-112.28e-076.70961118
GO:0004298threonine-type endopeptidase activity2.91e-114.75e-076.55761120
GO:0044281small molecule metabolic process1.16e-101.90e-062.34821571295
GO:0070062extracellular vesicular exosome1.51e-102.46e-061.80428982516
GO:0005838proteasome regulatory particle2.10e-103.43e-067.0315712
GO:0016020membrane6.65e-101.09e-052.04823801746
GO:0019773proteasome core complex, alpha-subunit complex6.35e-091.04e-047.294458
GO:0044822poly(A) RNA binding1.27e-072.07e-032.22016501078
GO:0005515protein binding2.00e-073.26e-030.961381726127
GO:0005634nucleus4.23e-076.90e-031.101331314828
GO:0006414translational elongation4.79e-077.82e-034.34061193
GO:0005524ATP binding5.03e-078.21e-031.97817461354
GO:0006412translation7.15e-071.17e-023.417815235
GO:0019058viral life cycle1.68e-062.74e-024.033610115
GO:0005730nucleolus2.20e-063.60e-021.74618701684
GO:0006413translational initiation3.58e-065.85e-023.846612131
GO:0019083viral transcription5.75e-069.39e-024.2765881
GO:0006415translational termination8.18e-061.33e-014.1735887
GO:0003723RNA binding1.51e-052.47e-012.822819355
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.95e-053.19e-013.91558104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.04e-054.97e-013.783510114
GO:0030529ribonucleoprotein complex3.04e-054.97e-013.78358114
GO:0005844polysome6.68e-051.00e+005.2353425
GO:0003735structural constituent of ribosome8.40e-051.00e+003.47658141
GO:0016887ATPase activity9.28e-051.00e+003.44657144
GO:0006271DNA strand elongation involved in DNA replication1.29e-041.00e+004.9253931
GO:0034644cellular response to UV1.42e-041.00e+004.8793532
GO:0044267cellular protein metabolic process1.57e-041.00e+002.343824495
GO:0005737cytoplasm1.70e-041.00e+000.98125983976
GO:0016363nuclear matrix2.08e-041.00e+003.77041192
GO:0022627cytosolic small ribosomal subunit2.57e-041.00e+004.5943339
GO:0006983ER overload response3.53e-041.00e+006.124229
GO:0043234protein complex3.67e-041.00e+002.650617300
GO:0010226response to lithium ion4.41e-041.00e+005.9722210
GO:0019901protein kinase binding5.17e-041.00e+002.557621320
GO:0031571mitotic G1 DNA damage checkpoint5.38e-041.00e+005.8352311
GO:0003684damaged DNA binding5.70e-041.00e+004.20731151
GO:0032886regulation of microtubule-based process6.44e-041.00e+005.7092412
GO:0006260DNA replication6.68e-041.00e+003.328412125
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.75e-041.00e+004.1243554
GO:0002039p53 binding7.12e-041.00e+004.0983755
GO:0000932cytoplasmic mRNA processing body7.51e-041.00e+004.0723356
GO:0042273ribosomal large subunit biogenesis7.59e-041.00e+005.5942413
GO:0030234enzyme regulator activity7.59e-041.00e+005.5942313
GO:0035267NuA4 histone acetyltransferase complex8.84e-041.00e+005.4872414
GO:0019903protein phosphatase binding1.06e-031.00e+003.9023463
GO:0042176regulation of protein catabolic process1.16e-031.00e+005.2942316
GO:0003678DNA helicase activity1.64e-031.00e+005.0462319
GO:0006297nucleotide-excision repair, DNA gap filling2.21e-031.00e+004.8352522
GO:0032201telomere maintenance via semi-conservative replication2.21e-031.00e+004.8352722
GO:0006270DNA replication initiation2.21e-031.00e+004.8352522
GO:0043044ATP-dependent chromatin remodeling2.41e-031.00e+004.7702423
GO:0031625ubiquitin protein ligase binding2.56e-031.00e+002.802413180
GO:0000060protein import into nucleus, translocation2.63e-031.00e+004.7092424
GO:0006200ATP catabolic process2.72e-031.00e+002.373514303
GO:0051059NF-kappaB binding2.85e-031.00e+004.6502325
GO:0000722telomere maintenance via recombination3.08e-031.00e+004.5942726
GO:0002842positive regulation of T cell mediated immune response to tumor cell3.19e-031.00e+008.294111
GO:0090271positive regulation of fibroblast growth factor production3.19e-031.00e+008.294111
GO:0001042RNA polymerase I core binding3.19e-031.00e+008.294111
GO:0048291isotype switching to IgG isotypes3.19e-031.00e+008.294111
GO:0090362positive regulation of platelet-derived growth factor production3.19e-031.00e+008.294111
GO:0035639purine ribonucleoside triphosphate binding3.19e-031.00e+008.294111
GO:0019521D-gluconate metabolic process3.19e-031.00e+008.294111
GO:0005098Ran GTPase activator activity3.19e-031.00e+008.294111
GO:0004055argininosuccinate synthase activity3.19e-031.00e+008.294111
GO:0002368B cell cytokine production3.19e-031.00e+008.294111
GO:1903038negative regulation of leukocyte cell-cell adhesion3.19e-031.00e+008.294111
GO:0004149dihydrolipoyllysine-residue succinyltransferase activity3.19e-031.00e+008.294111
GO:0004512inositol-3-phosphate synthase activity3.19e-031.00e+008.294111
GO:0060453regulation of gastric acid secretion3.19e-031.00e+008.294111
GO:0000053argininosuccinate metabolic process3.19e-031.00e+008.294111
GO:0035633maintenance of blood-brain barrier3.19e-031.00e+008.294111
GO:0019843rRNA binding3.32e-031.00e+004.5392327
GO:0001649osteoblast differentiation3.43e-031.00e+003.3093695
GO:0031492nucleosomal DNA binding3.57e-031.00e+004.4872428
GO:0071456cellular response to hypoxia3.75e-031.00e+003.2643498
GO:0006099tricarboxylic acid cycle3.83e-031.00e+004.4362329
GO:0033572transferrin transport4.65e-031.00e+004.2942632
GO:1903507negative regulation of nucleic acid-templated transcription4.65e-031.00e+004.2942232
GO:0001085RNA polymerase II transcription factor binding5.23e-031.00e+004.2072234
GO:0045429positive regulation of nitric oxide biosynthetic process5.54e-031.00e+004.1652335
GO:0016301kinase activity6.17e-031.00e+004.0852337
GO:00515394 iron, 4 sulfur cluster binding6.17e-031.00e+004.0852337
GO:0005925focal adhesion6.33e-031.00e+002.085518370
GO:0051054positive regulation of DNA metabolic process6.36e-031.00e+007.294112
GO:0097252oligodendrocyte apoptotic process6.36e-031.00e+007.294112
GO:0006272leading strand elongation6.36e-031.00e+007.294122
GO:0045252oxoglutarate dehydrogenase complex6.36e-031.00e+007.294122
GO:0003994aconitate hydratase activity6.36e-031.00e+007.294112
GO:0006407rRNA export from nucleus6.36e-031.00e+007.294112
GO:0071418cellular response to amine stimulus6.36e-031.00e+007.294112
GO:0071242cellular response to ammonium ion6.36e-031.00e+007.294112
GO:0071109superior temporal gyrus development6.36e-031.00e+007.294112
GO:2000077negative regulation of type B pancreatic cell development6.36e-031.00e+007.294112
GO:0090343positive regulation of cell aging6.36e-031.00e+007.294112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.36e-031.00e+007.294112
GO:0019322pentose biosynthetic process6.36e-031.00e+007.294112
GO:0004832valine-tRNA ligase activity6.36e-031.00e+007.294112
GO:0010046response to mycotoxin6.36e-031.00e+007.294112
GO:0032227negative regulation of synaptic transmission, dopaminergic6.36e-031.00e+007.294112
GO:00515383 iron, 4 sulfur cluster binding6.36e-031.00e+007.294112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process6.36e-031.00e+007.294122
GO:1901525negative regulation of macromitophagy6.36e-031.00e+007.294112
GO:0002176male germ cell proliferation6.36e-031.00e+007.294112
GO:0004103choline kinase activity6.36e-031.00e+007.294112
GO:0006438valyl-tRNA aminoacylation6.36e-031.00e+007.294112
GO:0032633interleukin-4 production6.36e-031.00e+007.294112
GO:0005055laminin receptor activity6.36e-031.00e+007.294112
GO:0001865NK T cell differentiation6.36e-031.00e+007.294112
GO:0007127meiosis I6.36e-031.00e+007.294112
GO:0004666prostaglandin-endoperoxide synthase activity6.36e-031.00e+007.294112
GO:0005759mitochondrial matrix6.41e-031.00e+002.430412233
GO:0006284base-excision repair6.84e-031.00e+004.0092739
GO:0032508DNA duplex unwinding7.90e-031.00e+003.9022442
GO:0006418tRNA aminoacylation for protein translation7.90e-031.00e+003.9022542
GO:0042110T cell activation8.27e-031.00e+003.8682343
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding8.65e-031.00e+003.8352244
GO:0000790nuclear chromatin8.74e-031.00e+002.82437133
GO:0045727positive regulation of translation9.42e-031.00e+003.7702446
GO:0061574ASAP complex9.53e-031.00e+006.709113
GO:0014043negative regulation of neuron maturation9.53e-031.00e+006.709113
GO:0000320re-entry into mitotic cell cycle9.53e-031.00e+006.709113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity9.53e-031.00e+006.709113
GO:2000466negative regulation of glycogen (starch) synthase activity9.53e-031.00e+006.709113
GO:1900126negative regulation of hyaluronan biosynthetic process9.53e-031.00e+006.709113
GO:0006458'de novo' protein folding9.53e-031.00e+006.709113
GO:0035033histone deacetylase regulator activity9.53e-031.00e+006.709113
GO:0006021inositol biosynthetic process9.53e-031.00e+006.709113
GO:0002360T cell lineage commitment9.53e-031.00e+006.709113
GO:0009051pentose-phosphate shunt, oxidative branch9.53e-031.00e+006.709113
GO:0033512L-lysine catabolic process to acetyl-CoA via saccharopine9.53e-031.00e+006.709113
GO:0034103regulation of tissue remodeling9.53e-031.00e+006.709113
GO:0006432phenylalanyl-tRNA aminoacylation9.53e-031.00e+006.709113
GO:0030135coated vesicle9.53e-031.00e+006.709113
GO:0006526arginine biosynthetic process9.53e-031.00e+006.709113
GO:0009750response to fructose9.53e-031.00e+006.709113
GO:0035794positive regulation of mitochondrial membrane permeability9.53e-031.00e+006.709113
GO:0071899negative regulation of estrogen receptor binding9.53e-031.00e+006.709113
GO:0051097negative regulation of helicase activity9.53e-031.00e+006.709113
GO:0005850eukaryotic translation initiation factor 2 complex9.53e-031.00e+006.709113
GO:0071733transcriptional activation by promoter-enhancer looping9.53e-031.00e+006.709113
GO:0044027hypermethylation of CpG island9.53e-031.00e+006.709113
GO:0071400cellular response to oleic acid9.53e-031.00e+006.709113
GO:0090336positive regulation of brown fat cell differentiation9.53e-031.00e+006.709113
GO:0071439clathrin complex9.53e-031.00e+006.709113
GO:0050473arachidonate 15-lipoxygenase activity9.53e-031.00e+006.709113
GO:0050727regulation of inflammatory response9.82e-031.00e+003.7392347
GO:0006281DNA repair9.86e-031.00e+002.250422264
GO:0022625cytosolic large ribosomal subunit1.06e-021.00e+003.6792549
GO:0043065positive regulation of apoptotic process1.12e-021.00e+002.19648274
GO:0006091generation of precursor metabolites and energy1.15e-021.00e+003.6222351
GO:003068690S preribosome1.27e-021.00e+006.294114
GO:0070294renal sodium ion absorption1.27e-021.00e+006.294114
GO:0004305ethanolamine kinase activity1.27e-021.00e+006.294114
GO:0019788NEDD8 ligase activity1.27e-021.00e+006.294114
GO:0000052citrulline metabolic process1.27e-021.00e+006.294114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.27e-021.00e+006.294114
GO:0043125ErbB-3 class receptor binding1.27e-021.00e+006.294114
GO:0002326B cell lineage commitment1.27e-021.00e+006.294114
GO:0051534negative regulation of NFAT protein import into nucleus1.27e-021.00e+006.294114
GO:0033088negative regulation of immature T cell proliferation in thymus1.27e-021.00e+006.294114
GO:0006273lagging strand elongation1.27e-021.00e+006.294114
GO:0032232negative regulation of actin filament bundle assembly1.27e-021.00e+006.294114
GO:0003896DNA primase activity1.27e-021.00e+006.294124
GO:0071782endoplasmic reticulum tubular network1.27e-021.00e+006.294114
GO:0000774adenyl-nucleotide exchange factor activity1.27e-021.00e+006.294114
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.27e-021.00e+006.294114
GO:0000212meiotic spindle organization1.27e-021.00e+006.294114
GO:0005658alpha DNA polymerase:primase complex1.27e-021.00e+006.294114
GO:0032051clathrin light chain binding1.27e-021.00e+006.294114
GO:0090403oxidative stress-induced premature senescence1.27e-021.00e+006.294114
GO:0004826phenylalanine-tRNA ligase activity1.27e-021.00e+006.294114
GO:0031467Cul7-RING ubiquitin ligase complex1.27e-021.00e+006.294114
GO:0006610ribosomal protein import into nucleus1.27e-021.00e+006.294114
GO:1903077negative regulation of protein localization to plasma membrane1.27e-021.00e+006.294114
GO:0003725double-stranded RNA binding1.28e-021.00e+003.5392654
GO:0019899enzyme binding1.32e-021.00e+002.124411288
GO:0008217regulation of blood pressure1.47e-021.00e+003.4362558
GO:0051087chaperone binding1.52e-021.00e+003.4112659
GO:0000723telomere maintenance1.52e-021.00e+003.4112859
GO:0005643nuclear pore1.52e-021.00e+003.4112459
GO:1900029positive regulation of ruffle assembly1.58e-021.00e+005.972115
GO:0044770cell cycle phase transition1.58e-021.00e+005.972115
GO:0031622positive regulation of fever generation1.58e-021.00e+005.972125
GO:0001882nucleoside binding1.58e-021.00e+005.972115
GO:2000001regulation of DNA damage checkpoint1.58e-021.00e+005.972115
GO:0070852cell body fiber1.58e-021.00e+005.972115
GO:0045986negative regulation of smooth muscle contraction1.58e-021.00e+005.972115
GO:0006269DNA replication, synthesis of RNA primer1.58e-021.00e+005.972125
GO:0010571positive regulation of nuclear cell cycle DNA replication1.58e-021.00e+005.972115
GO:0043248proteasome assembly1.58e-021.00e+005.972115
GO:0036016cellular response to interleukin-31.58e-021.00e+005.972115
GO:0030891VCB complex1.58e-021.00e+005.972125
GO:0017081chloride channel regulator activity1.58e-021.00e+005.972115
GO:0005827polar microtubule1.58e-021.00e+005.972115
GO:0032411positive regulation of transporter activity1.58e-021.00e+005.972115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.58e-021.00e+005.972125
GO:0071636positive regulation of transforming growth factor beta production1.58e-021.00e+005.972115
GO:0097371MDM2/MDM4 family protein binding1.58e-021.00e+005.972115
GO:0031461cullin-RING ubiquitin ligase complex1.58e-021.00e+005.972115
GO:0071169establishment of protein localization to chromatin1.58e-021.00e+005.972115
GO:0046696lipopolysaccharide receptor complex1.58e-021.00e+005.972115
GO:0031915positive regulation of synaptic plasticity1.58e-021.00e+005.972115
GO:2000738positive regulation of stem cell differentiation1.58e-021.00e+005.972115
GO:0006102isocitrate metabolic process1.58e-021.00e+005.972115
GO:0000730DNA recombinase assembly1.58e-021.00e+005.972135
GO:0031394positive regulation of prostaglandin biosynthetic process1.58e-021.00e+005.972115
GO:0006302double-strand break repair1.67e-021.00e+003.3402862
GO:0038095Fc-epsilon receptor signaling pathway1.72e-021.00e+002.46137171
GO:0071260cellular response to mechanical stimulus1.88e-021.00e+003.2502466
GO:0003688DNA replication origin binding1.90e-021.00e+005.709116
GO:0010666positive regulation of cardiac muscle cell apoptotic process1.90e-021.00e+005.709116
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process1.90e-021.00e+005.709116
GO:0006531aspartate metabolic process1.90e-021.00e+005.709116
GO:0002309T cell proliferation involved in immune response1.90e-021.00e+005.709116
GO:0006101citrate metabolic process1.90e-021.00e+005.709116
GO:0030118clathrin coat1.90e-021.00e+005.709116
GO:0010042response to manganese ion1.90e-021.00e+005.709116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.90e-021.00e+005.709116
GO:0070245positive regulation of thymocyte apoptotic process1.90e-021.00e+005.709116
GO:0032853positive regulation of Ran GTPase activity1.90e-021.00e+005.709116
GO:0010614negative regulation of cardiac muscle hypertrophy1.90e-021.00e+005.709116
GO:0002181cytoplasmic translation1.90e-021.00e+005.709116
GO:0030130clathrin coat of trans-Golgi network vesicle1.90e-021.00e+005.709116
GO:0031466Cul5-RING ubiquitin ligase complex1.90e-021.00e+005.709116
GO:0050774negative regulation of dendrite morphogenesis1.90e-021.00e+005.709116
GO:0030957Tat protein binding1.90e-021.00e+005.709146
GO:0007406negative regulation of neuroblast proliferation1.90e-021.00e+005.709116
GO:0045943positive regulation of transcription from RNA polymerase I promoter1.90e-021.00e+005.709116
GO:0003697single-stranded DNA binding2.04e-021.00e+003.1852969
GO:0006289nucleotide-excision repair2.04e-021.00e+003.18521269
GO:0008283cell proliferation2.10e-021.00e+001.923412331
GO:0031462Cul2-RING ubiquitin ligase complex2.21e-021.00e+005.487127
GO:0060416response to growth hormone2.21e-021.00e+005.487117
GO:0046826negative regulation of protein export from nucleus2.21e-021.00e+005.487117
GO:0000028ribosomal small subunit assembly2.21e-021.00e+005.487117
GO:0002161aminoacyl-tRNA editing activity2.21e-021.00e+005.487127
GO:0090050positive regulation of cell migration involved in sprouting angiogenesis2.21e-021.00e+005.487117
GO:0006657CDP-choline pathway2.21e-021.00e+005.487117
GO:0033180proton-transporting V-type ATPase, V1 domain2.21e-021.00e+005.487127
GO:0030132clathrin coat of coated pit2.21e-021.00e+005.487117
GO:0071499cellular response to laminar fluid shear stress2.21e-021.00e+005.487117
GO:0031497chromatin assembly2.21e-021.00e+005.487117
GO:0000930gamma-tubulin complex2.21e-021.00e+005.487117
GO:0005813centrosome2.27e-021.00e+001.889412339
GO:0032355response to estradiol2.27e-021.00e+003.1042573
GO:0000785chromatin2.27e-021.00e+003.1042573
GO:0000733DNA strand renaturation2.52e-021.00e+005.294118
GO:0006554lysine catabolic process2.52e-021.00e+005.294128
GO:0045116protein neddylation2.52e-021.00e+005.294128
GO:0045719negative regulation of glycogen biosynthetic process2.52e-021.00e+005.294118
GO:0030728ovulation2.52e-021.00e+005.294118
GO:0031464Cul4A-RING E3 ubiquitin ligase complex2.52e-021.00e+005.294128
GO:0060539diaphragm development2.52e-021.00e+005.294118
GO:0070688MLL5-L complex2.52e-021.00e+005.294118
GO:0000812Swr1 complex2.52e-021.00e+005.294138
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway2.52e-021.00e+005.294118
GO:0035372protein localization to microtubule2.52e-021.00e+005.294118
GO:0071013catalytic step 2 spliceosome2.62e-021.00e+002.9902779
GO:0003924GTPase activity2.68e-021.00e+002.21439203
GO:0004716receptor signaling protein tyrosine kinase activity2.83e-021.00e+005.124119
GO:0007494midgut development2.83e-021.00e+005.124119
GO:0031065positive regulation of histone deacetylation2.83e-021.00e+005.124119
GO:0008139nuclear localization sequence binding2.83e-021.00e+005.124129
GO:0042555MCM complex2.83e-021.00e+005.124129
GO:0008494translation activator activity2.83e-021.00e+005.124119
GO:0048156tau protein binding2.83e-021.00e+005.124119
GO:0032609interferon-gamma production2.83e-021.00e+005.124119
GO:0030837negative regulation of actin filament polymerization2.83e-021.00e+005.124119
GO:0007167enzyme linked receptor protein signaling pathway2.83e-021.00e+005.124119
GO:0005681spliceosomal complex2.88e-021.00e+002.9192383
GO:0047485protein N-terminus binding3.07e-021.00e+002.8682486
GO:0043032positive regulation of macrophage activation3.14e-021.00e+004.9721110
GO:0090399replicative senescence3.14e-021.00e+004.9721110
GO:0046902regulation of mitochondrial membrane permeability3.14e-021.00e+004.9721110
GO:0051497negative regulation of stress fiber assembly3.14e-021.00e+004.9721110
GO:0051604protein maturation3.14e-021.00e+004.9721110
GO:0006450regulation of translational fidelity3.14e-021.00e+004.9721210
GO:0015643toxic substance binding3.14e-021.00e+004.9721110
GO:0000731DNA synthesis involved in DNA repair3.14e-021.00e+004.9721110
GO:0071318cellular response to ATP3.14e-021.00e+004.9721110
GO:0030877beta-catenin destruction complex3.14e-021.00e+004.9721210
GO:0006184GTP catabolic process3.29e-021.00e+002.09839220
GO:0045945positive regulation of transcription from RNA polymerase III promoter3.45e-021.00e+004.8351111
GO:0032727positive regulation of interferon-alpha production3.45e-021.00e+004.8351111
GO:0006693prostaglandin metabolic process3.45e-021.00e+004.8351111
GO:0045120pronucleus3.45e-021.00e+004.8351111
GO:0000050urea cycle3.45e-021.00e+004.8351111
GO:0006098pentose-phosphate shunt3.45e-021.00e+004.8351311
GO:0008340determination of adult lifespan3.45e-021.00e+004.8351111
GO:0010569regulation of double-strand break repair via homologous recombination3.45e-021.00e+004.8351111
GO:0071850mitotic cell cycle arrest3.45e-021.00e+004.8351111
GO:0006928cellular component movement3.47e-021.00e+002.7702792
GO:0016605PML body3.47e-021.00e+002.7702592
GO:0042470melanosome3.47e-021.00e+002.77021092
GO:0005200structural constituent of cytoskeleton3.54e-021.00e+002.7552793
GO:0051082unfolded protein binding3.68e-021.00e+002.7242695
GO:0006364rRNA processing3.75e-021.00e+002.7092596
GO:00709353'-UTR-mediated mRNA stabilization3.76e-021.00e+004.7091212
GO:0042633hair cycle3.76e-021.00e+004.7091112
GO:0019372lipoxygenase pathway3.76e-021.00e+004.7091112
GO:0008380RNA splicing3.76e-021.00e+002.021313232
GO:0070266necroptotic process3.76e-021.00e+004.7091112
GO:0032461positive regulation of protein oligomerization3.76e-021.00e+004.7091112
GO:0009303rRNA transcription3.76e-021.00e+004.7091112
GO:0010971positive regulation of G2/M transition of mitotic cell cycle3.76e-021.00e+004.7091112
GO:0019985translesion synthesis3.76e-021.00e+004.7091212
GO:0034236protein kinase A catalytic subunit binding3.76e-021.00e+004.7091112
GO:0043968histone H2A acetylation3.76e-021.00e+004.7091312
GO:0050321tau-protein kinase activity3.76e-021.00e+004.7091112
GO:0001530lipopolysaccharide binding4.07e-021.00e+004.5941213
GO:0046827positive regulation of protein export from nucleus4.07e-021.00e+004.5941213
GO:0006646phosphatidylethanolamine biosynthetic process4.07e-021.00e+004.5941213
GO:0005662DNA replication factor A complex4.07e-021.00e+004.5941313
GO:0051926negative regulation of calcium ion transport4.07e-021.00e+004.5941113
GO:0008266poly(U) RNA binding4.07e-021.00e+004.5941113
GO:0051131chaperone-mediated protein complex assembly4.07e-021.00e+004.5941113
GO:0031333negative regulation of protein complex assembly4.37e-021.00e+004.4871114
GO:0001516prostaglandin biosynthetic process4.37e-021.00e+004.4871114
GO:0006607NLS-bearing protein import into nucleus4.37e-021.00e+004.4871214
GO:0031011Ino80 complex4.37e-021.00e+004.4871314
GO:0048168regulation of neuronal synaptic plasticity4.37e-021.00e+004.4871114
GO:0030330DNA damage response, signal transduction by p53 class mediator4.37e-021.00e+004.4871114
GO:0070542response to fatty acid4.37e-021.00e+004.4871114
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator4.37e-021.00e+004.4871214
GO:2000378negative regulation of reactive oxygen species metabolic process4.37e-021.00e+004.4871114
GO:0007020microtubule nucleation4.37e-021.00e+004.4871114
GO:0031334positive regulation of protein complex assembly4.37e-021.00e+004.4871214
GO:0009651response to salt stress4.37e-021.00e+004.4871214
GO:0019371cyclooxygenase pathway4.37e-021.00e+004.4871114
GO:0048568embryonic organ development4.37e-021.00e+004.4871114
GO:0006349regulation of gene expression by genetic imprinting4.68e-021.00e+004.3871115
GO:0033280response to vitamin D4.68e-021.00e+004.3871115
GO:0046961proton-transporting ATPase activity, rotational mechanism4.68e-021.00e+004.3871315
GO:0045987positive regulation of smooth muscle contraction4.68e-021.00e+004.3871115
GO:0008654phospholipid biosynthetic process4.68e-021.00e+004.3871115
GO:0035066positive regulation of histone acetylation4.68e-021.00e+004.3871115
GO:0042026protein refolding4.68e-021.00e+004.3871215
GO:0048025negative regulation of mRNA splicing, via spliceosome4.68e-021.00e+004.3871115
GO:0015630microtubule cytoskeleton4.96e-021.00e+002.48725112
GO:0050998nitric-oxide synthase binding4.98e-021.00e+004.2941116
GO:0051968positive regulation of synaptic transmission, glutamatergic4.98e-021.00e+004.2941116
GO:0007520myoblast fusion4.98e-021.00e+004.2941116
GO:0051603proteolysis involved in cellular protein catabolic process4.98e-021.00e+004.2941216
GO:0046034ATP metabolic process4.98e-021.00e+004.2941116
GO:00084083'-5' exonuclease activity4.98e-021.00e+004.2941216
GO:0005819spindle5.11e-021.00e+002.46127114
GO:0048015phosphatidylinositol-mediated signaling5.19e-021.00e+002.44923115
GO:0042149cellular response to glucose starvation5.28e-021.00e+004.2071117
GO:0035255ionotropic glutamate receptor binding5.28e-021.00e+004.2071117
GO:0003746translation elongation factor activity5.28e-021.00e+004.2071317
GO:0075733intracellular transport of virus5.28e-021.00e+004.2071217
GO:0072562blood microparticle5.28e-021.00e+002.43624116
GO:0010243response to organonitrogen compound5.28e-021.00e+004.2071217
GO:0005635nuclear envelope5.28e-021.00e+002.43626116
GO:0006309apoptotic DNA fragmentation5.28e-021.00e+004.2071117
GO:0070372regulation of ERK1 and ERK2 cascade5.28e-021.00e+004.2071117
GO:0050870positive regulation of T cell activation5.28e-021.00e+004.2071117
GO:0044237cellular metabolic process5.44e-021.00e+002.41123118
GO:0017025TBP-class protein binding5.59e-021.00e+004.1241218
GO:0071392cellular response to estradiol stimulus5.59e-021.00e+004.1241118
GO:0070064proline-rich region binding5.59e-021.00e+004.1241218
GO:0031122cytoplasmic microtubule organization5.59e-021.00e+004.1241218
GO:0035861site of double-strand break5.59e-021.00e+004.1241118
GO:0010800positive regulation of peptidyl-threonine phosphorylation5.59e-021.00e+004.1241118
GO:0005657replication fork5.59e-021.00e+004.1241318
GO:0042346positive regulation of NF-kappaB import into nucleus5.59e-021.00e+004.1241218
GO:0005246calcium channel regulator activity5.59e-021.00e+004.1241118
GO:0051721protein phosphatase 2A binding5.59e-021.00e+004.1241118
GO:0006303double-strand break repair via nonhomologous end joining5.59e-021.00e+004.1241318
GO:0006325chromatin organization5.85e-021.00e+002.35124123
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.89e-021.00e+004.0461119
GO:0035035histone acetyltransferase binding5.89e-021.00e+004.0461119
GO:0071158positive regulation of cell cycle arrest5.89e-021.00e+004.0461119
GO:0046697decidualization5.89e-021.00e+004.0461119
GO:0032733positive regulation of interleukin-10 production5.89e-021.00e+004.0461119
GO:0007088regulation of mitosis5.89e-021.00e+004.0461119
GO:1903506regulation of nucleic acid-templated transcription5.89e-021.00e+004.0461119
GO:0010165response to X-ray5.89e-021.00e+004.0461219
GO:0035145exon-exon junction complex5.89e-021.00e+004.0461219
GO:0048863stem cell differentiation5.89e-021.00e+004.0461119
GO:0004601peroxidase activity5.89e-021.00e+004.0461119
GO:0007219Notch signaling pathway6.02e-021.00e+002.32824125
GO:0006468protein phosphorylation6.11e-021.00e+001.427410467
GO:0015078hydrogen ion transmembrane transporter activity6.19e-021.00e+003.9721320
GO:0071549cellular response to dexamethasone stimulus6.19e-021.00e+003.9721120
GO:0051090regulation of sequence-specific DNA binding transcription factor activity6.19e-021.00e+003.9721120
GO:0005719nuclear euchromatin6.19e-021.00e+003.9721220
GO:0002931response to ischemia6.19e-021.00e+003.9721120
GO:0008045motor neuron axon guidance6.19e-021.00e+003.9721120
GO:0005680anaphase-promoting complex6.19e-021.00e+003.9721420
GO:0016597amino acid binding6.19e-021.00e+003.9721120
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator6.19e-021.00e+003.9721120
GO:0006298mismatch repair6.19e-021.00e+003.9721620
GO:0042493response to drug6.39e-021.00e+001.709311288
GO:0007369gastrulation6.49e-021.00e+003.9021121
GO:0001954positive regulation of cell-matrix adhesion6.49e-021.00e+003.9021121
GO:0008156negative regulation of DNA replication6.49e-021.00e+003.9021121
GO:0030010establishment of cell polarity6.49e-021.00e+003.9021221
GO:0000718nucleotide-excision repair, DNA damage removal6.49e-021.00e+003.9021521
GO:0018108peptidyl-tyrosine phosphorylation6.71e-021.00e+002.23923133
GO:0005669transcription factor TFIID complex6.78e-021.00e+003.8351122
GO:0014065phosphatidylinositol 3-kinase signaling6.78e-021.00e+003.8351122
GO:0090200positive regulation of release of cytochrome c from mitochondria6.78e-021.00e+003.8351122
GO:0017080sodium channel regulator activity6.78e-021.00e+003.8351122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle6.78e-021.00e+003.8351322
GO:0006656phosphatidylcholine biosynthetic process6.78e-021.00e+003.8351322
GO:0030863cortical cytoskeleton6.78e-021.00e+003.8351122
GO:0036464cytoplasmic ribonucleoprotein granule6.78e-021.00e+003.8351422
GO:0042802identical protein binding7.07e-021.00e+001.354418491
GO:0031463Cul3-RING ubiquitin ligase complex7.08e-021.00e+003.7701223
GO:0043236laminin binding7.08e-021.00e+003.7701123
GO:0045907positive regulation of vasoconstriction7.08e-021.00e+003.7701123
GO:0010575positive regulation vascular endothelial growth factor production7.08e-021.00e+003.7701123
GO:0071346cellular response to interferon-gamma7.08e-021.00e+003.7701123
GO:0006513protein monoubiquitination7.08e-021.00e+003.7701123
GO:0048709oligodendrocyte differentiation7.08e-021.00e+003.7701123
GO:0008135translation factor activity, nucleic acid binding7.38e-021.00e+003.7091424
GO:0010634positive regulation of epithelial cell migration7.38e-021.00e+003.7091124
GO:0001836release of cytochrome c from mitochondria7.38e-021.00e+003.7091224
GO:0045765regulation of angiogenesis7.38e-021.00e+003.7091124
GO:0048147negative regulation of fibroblast proliferation7.38e-021.00e+003.7091124
GO:0000794condensed nuclear chromosome7.38e-021.00e+003.7091224
GO:0005977glycogen metabolic process7.38e-021.00e+003.7091124
GO:2000379positive regulation of reactive oxygen species metabolic process7.38e-021.00e+003.7091124
GO:0006611protein export from nucleus7.67e-021.00e+003.6501425
GO:0032781positive regulation of ATPase activity7.67e-021.00e+003.6501125
GO:0042100B cell proliferation7.67e-021.00e+003.6501125
GO:0001816cytokine production7.67e-021.00e+003.6501125
GO:0008536Ran GTPase binding7.67e-021.00e+003.6501225
GO:0030016myofibril7.67e-021.00e+003.6501125
GO:0071479cellular response to ionizing radiation7.67e-021.00e+003.6501125
GO:0007569cell aging7.67e-021.00e+003.6501225
GO:0019838growth factor binding7.67e-021.00e+003.6501125
GO:0042113B cell activation7.67e-021.00e+003.6501225
GO:0032735positive regulation of interleukin-12 production7.67e-021.00e+003.6501125
GO:0004674protein serine/threonine kinase activity7.71e-021.00e+001.59436312
GO:0061024membrane organization7.89e-021.00e+002.10425146
GO:0070979protein K11-linked ubiquitination7.97e-021.00e+003.5941326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia7.97e-021.00e+003.5941226
GO:0015459potassium channel regulator activity7.97e-021.00e+003.5941126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway7.97e-021.00e+003.5941326
GO:0010043response to zinc ion7.97e-021.00e+003.5941126
GO:0006457protein folding8.17e-021.00e+002.07528149
GO:0004003ATP-dependent DNA helicase activity8.26e-021.00e+003.5391327
GO:0007616long-term memory8.26e-021.00e+003.5391127
GO:0071339MLL1 complex8.26e-021.00e+003.5391327
GO:0007422peripheral nervous system development8.26e-021.00e+003.5391127
GO:0015991ATP hydrolysis coupled proton transport8.55e-021.00e+003.4871428
GO:0043022ribosome binding8.55e-021.00e+003.4871328
GO:0043967histone H4 acetylation8.55e-021.00e+003.4871328
GO:0019894kinesin binding8.55e-021.00e+003.4871128
GO:0034612response to tumor necrosis factor8.55e-021.00e+003.4871228
GO:0000118histone deacetylase complex8.55e-021.00e+003.4871128
GO:0007411axon guidance8.60e-021.00e+001.52639327
GO:0005525GTP binding8.66e-021.00e+001.521311328
GO:0000381regulation of alternative mRNA splicing, via spliceosome8.85e-021.00e+003.4361229
GO:0019005SCF ubiquitin ligase complex8.85e-021.00e+003.4361129
GO:0003730mRNA 3'-UTR binding8.85e-021.00e+003.4361229
GO:0043198dendritic shaft8.85e-021.00e+003.4361129
GO:0010332response to gamma radiation8.85e-021.00e+003.4361229
GO:0003887DNA-directed DNA polymerase activity8.85e-021.00e+003.4361329
GO:0004712protein serine/threonine/tyrosine kinase activity8.85e-021.00e+003.4361129
GO:0030669clathrin-coated endocytic vesicle membrane8.85e-021.00e+003.4361129
GO:0006974cellular response to DNA damage stimulus9.02e-021.00e+001.99028158
GO:0008543fibroblast growth factor receptor signaling pathway9.12e-021.00e+001.98124159
GO:0006606protein import into nucleus9.14e-021.00e+003.3871130
GO:0023014signal transduction by phosphorylation9.14e-021.00e+003.3871130
GO:0051262protein tetramerization9.14e-021.00e+003.3871330
GO:0034504protein localization to nucleus9.14e-021.00e+003.3871230
GO:0021549cerebellum development9.14e-021.00e+003.3871130
GO:0004714transmembrane receptor protein tyrosine kinase activity9.14e-021.00e+003.3871230
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator9.14e-021.00e+003.3871230
GO:0043005neuron projection9.32e-021.00e+001.96324161
GO:0045171intercellular bridge9.43e-021.00e+003.3401231
GO:0050873brown fat cell differentiation9.43e-021.00e+003.3401231
GO:0017048Rho GTPase binding9.43e-021.00e+003.3401131
GO:0031623receptor internalization9.43e-021.00e+003.3401131
GO:0046677response to antibiotic9.43e-021.00e+003.3401231
GO:0016604nuclear body9.43e-021.00e+003.3401231
GO:0007094mitotic spindle assembly checkpoint9.43e-021.00e+003.3401531
GO:0000398mRNA splicing, via spliceosome9.71e-021.00e+001.928212165
GO:0050661NADP binding9.72e-021.00e+003.2941132
GO:0002250adaptive immune response9.72e-021.00e+003.2941132
GO:0007528neuromuscular junction development9.72e-021.00e+003.2941132
GO:0015992proton transport9.72e-021.00e+003.2941332
GO:0032091negative regulation of protein binding1.00e-011.00e+003.2501133
GO:2001244positive regulation of intrinsic apoptotic signaling pathway1.00e-011.00e+003.2501133
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.00e-011.00e+001.90225168
GO:0030282bone mineralization1.00e-011.00e+003.2501133
GO:0030971receptor tyrosine kinase binding1.00e-011.00e+003.2501233
GO:0001837epithelial to mesenchymal transition1.00e-011.00e+003.2501133
GO:0033077T cell differentiation in thymus1.00e-011.00e+003.2501233
GO:0006397mRNA processing1.01e-011.00e+001.89323169
GO:0030017sarcomere1.03e-011.00e+003.2071134
GO:0004175endopeptidase activity1.03e-011.00e+003.2071234
GO:0043407negative regulation of MAP kinase activity1.03e-011.00e+003.2071134
GO:0051701interaction with host1.03e-011.00e+003.2071434
GO:0005876spindle microtubule1.03e-011.00e+003.2071334
GO:0006953acute-phase response1.06e-011.00e+003.1651135
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand1.06e-011.00e+003.1651235
GO:0016607nuclear speck1.07e-011.00e+001.84324175
GO:0031965nuclear membrane1.08e-011.00e+001.83524176
GO:0032588trans-Golgi network membrane1.09e-011.00e+003.1241136
GO:0034332adherens junction organization1.09e-011.00e+003.1241136
GO:0051402neuron apoptotic process1.09e-011.00e+003.1241236
GO:0032855positive regulation of Rac GTPase activity1.09e-011.00e+003.1241136
GO:0007566embryo implantation1.09e-011.00e+003.1241136
GO:0030838positive regulation of actin filament polymerization1.09e-011.00e+003.1241236
GO:0006605protein targeting1.09e-011.00e+003.1241236
GO:0032755positive regulation of interleukin-6 production1.09e-011.00e+003.1241236
GO:0042552myelination1.09e-011.00e+003.1241136
GO:0001895retina homeostasis1.09e-011.00e+003.1241136
GO:0051084'de novo' posttranslational protein folding1.11e-011.00e+003.0851437
GO:0071377cellular response to glucagon stimulus1.11e-011.00e+003.0851137
GO:0003714transcription corepressor activity1.11e-011.00e+001.81027179
GO:0001756somitogenesis1.14e-011.00e+003.0461138
GO:0070527platelet aggregation1.14e-011.00e+003.0461238
GO:0090382phagosome maturation1.14e-011.00e+003.0461538
GO:0032729positive regulation of interferon-gamma production1.17e-011.00e+003.0091239
GO:0051496positive regulation of stress fiber assembly1.17e-011.00e+003.0091239
GO:0032092positive regulation of protein binding1.17e-011.00e+003.0091339
GO:0021766hippocampus development1.17e-011.00e+003.0091439
GO:0031490chromatin DNA binding1.17e-011.00e+003.0091239
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.20e-011.00e+002.9721240
GO:0000781chromosome, telomeric region1.20e-011.00e+002.9721240
GO:0045786negative regulation of cell cycle1.23e-011.00e+002.9361141
GO:0045785positive regulation of cell adhesion1.23e-011.00e+002.9361541
GO:0005546phosphatidylinositol-4,5-bisphosphate binding1.23e-011.00e+002.9361241
GO:0007173epidermal growth factor receptor signaling pathway1.24e-011.00e+001.71724191
GO:0071320cellular response to cAMP1.26e-011.00e+002.9021142
GO:0071230cellular response to amino acid stimulus1.26e-011.00e+002.9021242
GO:0071363cellular response to growth factor stimulus1.26e-011.00e+002.9021242
GO:0005902microvillus1.26e-011.00e+002.9021242
GO:0043647inositol phosphate metabolic process1.26e-011.00e+002.9021142
GO:0004715non-membrane spanning protein tyrosine kinase activity1.26e-011.00e+002.9021142
GO:0014070response to organic cyclic compound1.28e-011.00e+002.8681343
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.31e-011.00e+002.8351344
GO:0034613cellular protein localization1.31e-011.00e+002.8351144
GO:0006892post-Golgi vesicle-mediated transport1.31e-011.00e+002.8351244
GO:0050434positive regulation of viral transcription1.31e-011.00e+002.8351544
GO:0045087innate immune response1.32e-011.00e+001.027420616
GO:0015030Cajal body1.34e-011.00e+002.8021245
GO:0046982protein heterodimerization activity1.34e-011.00e+001.239311399
GO:0030136clathrin-coated vesicle1.37e-011.00e+002.7701146
GO:0043525positive regulation of neuron apoptotic process1.37e-011.00e+002.7701246
GO:0006283transcription-coupled nucleotide-excision repair1.37e-011.00e+002.7701846
GO:0021762substantia nigra development1.37e-011.00e+002.7701146
GO:0007612learning1.37e-011.00e+002.7701146
GO:0043406positive regulation of MAP kinase activity1.39e-011.00e+002.7391247
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.39e-011.00e+002.7391547
GO:0005507copper ion binding1.42e-011.00e+002.7091248
GO:0006950response to stress1.42e-011.00e+002.7091348
GO:0001701in utero embryonic development1.44e-011.00e+001.58026210
GO:0048661positive regulation of smooth muscle cell proliferation1.45e-011.00e+002.6791249
GO:0019369arachidonic acid metabolic process1.45e-011.00e+002.6791249
GO:0003743translation initiation factor activity1.45e-011.00e+002.6791449
GO:0019233sensory perception of pain1.45e-011.00e+002.6791149
GO:0035690cellular response to drug1.48e-011.00e+002.6501250
GO:0040008regulation of growth1.50e-011.00e+002.6221351
GO:0006986response to unfolded protein1.50e-011.00e+002.6221251
GO:0005905coated pit1.50e-011.00e+002.6221251
GO:0045444fat cell differentiation1.50e-011.00e+002.6221151
GO:0045732positive regulation of protein catabolic process1.50e-011.00e+002.6221451
GO:0030334regulation of cell migration1.53e-011.00e+002.5941252
GO:0090305nucleic acid phosphodiester bond hydrolysis1.59e-011.00e+002.5391254
GO:0007623circadian rhythm1.59e-011.00e+002.5391154
GO:0050679positive regulation of epithelial cell proliferation1.59e-011.00e+002.5391154
GO:0097193intrinsic apoptotic signaling pathway1.61e-011.00e+002.5131455
GO:0000226microtubule cytoskeleton organization1.61e-011.00e+002.5131355
GO:0006814sodium ion transport1.61e-011.00e+002.5131155
GO:0007613memory1.64e-011.00e+002.4871256
GO:0008104protein localization1.64e-011.00e+002.4871356
GO:0006968cellular defense response1.64e-011.00e+002.4871156
GO:0008565protein transporter activity1.67e-011.00e+002.4611257
GO:0006879cellular iron ion homeostasis1.67e-011.00e+002.4611557
GO:0000724double-strand break repair via homologous recombination1.67e-011.00e+002.4611657
GO:0012505endomembrane system1.67e-011.00e+002.4611257
GO:0007067mitotic nuclear division1.68e-011.00e+001.442213231
GO:0007202activation of phospholipase C activity1.69e-011.00e+002.4361158
GO:0002244hematopoietic progenitor cell differentiation1.69e-011.00e+002.4361158
GO:0045216cell-cell junction organization1.72e-011.00e+002.4111259
GO:0005840ribosome1.72e-011.00e+002.4111259
GO:0008013beta-catenin binding1.75e-011.00e+002.3871460
GO:0071356cellular response to tumor necrosis factor1.75e-011.00e+002.3871160
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway1.77e-011.00e+002.3631261
GO:0033138positive regulation of peptidyl-serine phosphorylation1.77e-011.00e+002.3631361
GO:0043204perikaryon1.80e-011.00e+002.3401162
GO:0051384response to glucocorticoid1.80e-011.00e+002.3401262
GO:0005901caveola1.82e-011.00e+002.3171363
GO:0000776kinetochore1.82e-011.00e+002.3171463
GO:0007596blood coagulation1.84e-011.00e+001.021314464
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.85e-011.00e+002.2941164
GO:0001558regulation of cell growth1.90e-011.00e+002.2501466
GO:0030141secretory granule1.93e-011.00e+002.2281267
GO:0006310DNA recombination1.93e-011.00e+002.2281467
GO:0000777condensed chromosome kinetochore1.95e-011.00e+002.2071268
GO:0042060wound healing1.95e-011.00e+002.2071168
GO:0006338chromatin remodeling1.95e-011.00e+002.2071468
GO:0018105peptidyl-serine phosphorylation1.98e-011.00e+002.1851169
GO:0050790regulation of catalytic activity1.98e-011.00e+002.1851369
GO:0030307positive regulation of cell growth2.01e-011.00e+002.1651270
GO:0035264multicellular organism growth2.01e-011.00e+002.1651170
GO:0034329cell junction assembly2.03e-011.00e+002.1441171
GO:0007584response to nutrient2.06e-011.00e+002.1241372
GO:0002020protease binding2.11e-011.00e+002.0851474
GO:0001843neural tube closure2.13e-011.00e+002.0651275
GO:0007265Ras protein signal transduction2.13e-011.00e+002.0651375
GO:0060070canonical Wnt signaling pathway2.13e-011.00e+002.0651375
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation2.13e-011.00e+002.0651175
GO:0000166nucleotide binding2.15e-011.00e+001.20726272
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.16e-011.00e+002.0461376
GO:0048011neurotrophin TRK receptor signaling pathway2.16e-011.00e+001.20126273
GO:0046474glycerophospholipid biosynthetic process2.16e-011.00e+002.0461376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.18e-011.00e+002.0271577
GO:0008584male gonad development2.18e-011.00e+002.0271277
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process2.18e-011.00e+002.0271677
GO:0001822kidney development2.23e-011.00e+001.9901379
GO:0002755MyD88-dependent toll-like receptor signaling pathway2.26e-011.00e+001.9721280
GO:0051301cell division2.28e-011.00e+001.9541681
GO:0071222cellular response to lipopolysaccharide2.28e-011.00e+001.9541181
GO:0001889liver development2.31e-011.00e+001.9361382
GO:0001726ruffle2.31e-011.00e+001.9361482
GO:0002576platelet degranulation2.31e-011.00e+001.9361482
GO:0004713protein tyrosine kinase activity2.31e-011.00e+001.9361282
GO:0048471perinuclear region of cytoplasm2.32e-011.00e+000.848312523
GO:0043197dendritic spine2.33e-011.00e+001.9191283
GO:0005739mitochondrion2.39e-011.00e+000.5855241046
GO:0006898receptor-mediated endocytosis2.41e-011.00e+001.8681286
GO:0050852T cell receptor signaling pathway2.45e-011.00e+001.8351288
GO:0090090negative regulation of canonical Wnt signaling pathway2.45e-011.00e+001.8351388
GO:0032321positive regulation of Rho GTPase activity2.45e-011.00e+001.8351188
GO:0009887organ morphogenesis2.48e-011.00e+001.8181289
GO:0006979response to oxidative stress2.50e-011.00e+001.8021490
GO:0000922spindle pole2.53e-011.00e+001.7861491
GO:0050821protein stabilization2.53e-011.00e+001.7861291
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.55e-011.00e+001.7701492
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.58e-011.00e+000.630419811
GO:0005856cytoskeleton2.61e-011.00e+001.01328311
GO:0016310phosphorylation2.62e-011.00e+001.7241295
GO:0030426growth cone2.67e-011.00e+001.6941397
GO:0005178integrin binding2.67e-011.00e+001.6941297
GO:0035556intracellular signal transduction2.68e-011.00e+000.98626317
GO:0030154cell differentiation2.77e-011.00e+000.95025325
GO:0004888transmembrane signaling receptor activity2.81e-011.00e+001.60811103
GO:0043235receptor complex2.83e-011.00e+001.59412104
GO:0014069postsynaptic density2.88e-011.00e+001.56611106
GO:0003682chromatin binding2.88e-011.00e+000.910212334
GO:0001934positive regulation of protein phosphorylation2.92e-011.00e+001.53915108
GO:0005741mitochondrial outer membrane2.92e-011.00e+001.53914108
GO:0031410cytoplasmic vesicle2.97e-011.00e+001.51312110
GO:0042127regulation of cell proliferation2.99e-011.00e+001.50014111
GO:0020037heme binding2.99e-011.00e+001.50012111
GO:0006461protein complex assembly2.99e-011.00e+001.50016111
GO:0030308negative regulation of cell growth3.04e-011.00e+001.47416113
GO:0008289lipid binding3.10e-011.00e+001.43611116
GO:0032496response to lipopolysaccharide3.23e-011.00e+001.36314122
GO:0007568aging3.26e-011.00e+001.35113123
GO:0008285negative regulation of cell proliferation3.27e-011.00e+000.774211367
GO:0051092positive regulation of NF-kappaB transcription factor activity3.30e-011.00e+001.32814125
GO:0007050cell cycle arrest3.32e-011.00e+001.31717126
GO:0006511ubiquitin-dependent protein catabolic process3.34e-011.00e+001.30515127
GO:0005506iron ion binding3.34e-011.00e+001.30513127
GO:0030036actin cytoskeleton organization3.39e-011.00e+001.28315129
GO:0007179transforming growth factor beta receptor signaling pathway3.41e-011.00e+001.27213130
GO:0016477cell migration3.43e-011.00e+001.26116131
GO:0046983protein dimerization activity3.43e-011.00e+001.26113131
GO:0009615response to virus3.45e-011.00e+001.25016132
GO:0031982vesicle3.49e-011.00e+001.228110134
GO:0006644phospholipid metabolic process3.55e-011.00e+001.19615137
GO:0000086G2/M transition of mitotic cell cycle3.55e-011.00e+001.19617137
GO:0045202synapse3.62e-011.00e+001.16513140
GO:0007507heart development3.64e-011.00e+001.15415141
GO:0005911cell-cell junction3.66e-011.00e+001.14413142
GO:0008286insulin receptor signaling pathway3.70e-011.00e+001.12416144
GO:0010628positive regulation of gene expression3.80e-011.00e+001.07514149
GO:0007166cell surface receptor signaling pathway3.80e-011.00e+001.07511149
GO:0016323basolateral plasma membrane3.80e-011.00e+001.07513149
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.84e-011.00e+001.05612151
GO:0010008endosome membrane3.96e-011.00e+000.99916157
GO:0005769early endosome3.97e-011.00e+000.99012158
GO:0046777protein autophosphorylation3.97e-011.00e+000.99013158
GO:0005198structural molecule activity3.99e-011.00e+000.98114159
GO:0045121membrane raft4.03e-011.00e+000.96318161
GO:0008022protein C-terminus binding4.03e-011.00e+000.96314161
GO:0034220ion transmembrane transport4.15e-011.00e+000.91012167
GO:0044212transcription regulatory region DNA binding4.22e-011.00e+000.87616171
GO:0030424axon4.24e-011.00e+000.86813172
GO:0006886intracellular protein transport4.26e-011.00e+000.85914173
GO:0000287magnesium ion binding4.28e-011.00e+000.85115174
GO:0004672protein kinase activity4.35e-011.00e+000.81812178
GO:0019904protein domain specific binding4.41e-011.00e+000.79416181
GO:0005764lysosome4.42e-011.00e+000.78612182
GO:0032403protein complex binding4.48e-011.00e+000.76317185
GO:0055114oxidation-reduction process4.56e-011.00e+000.384211481
GO:0001525angiogenesis4.74e-011.00e+000.65014200
GO:0030168platelet activation4.82e-011.00e+000.61519205
GO:0055085transmembrane transport4.91e-011.00e+000.28828514
GO:0005765lysosomal membrane5.04e-011.00e+000.52615218
GO:0046872metal ion binding5.05e-011.00e+000.0995241465
GO:0016324apical plasma membrane5.13e-011.00e+000.48712224
GO:0005622intracellular5.16e-011.00e+000.47415226
GO:0019221cytokine-mediated signaling pathway5.22e-011.00e+000.44913230
GO:0003713transcription coactivator activity5.36e-011.00e+000.393110239
GO:0008134transcription factor binding5.47e-011.00e+000.35118246
GO:0043025neuronal cell body5.58e-011.00e+000.30514254
GO:0004842ubiquitin-protein transferase activity5.61e-011.00e+000.29414256
GO:0005102receptor binding5.78e-011.00e+000.22815268
GO:0005783endoplasmic reticulum5.84e-011.00e+000.04129610
GO:0005975carbohydrate metabolic process5.86e-011.00e+000.19615274
GO:0006357regulation of transcription from RNA polymerase II promoter5.87e-011.00e+000.19116275
GO:0003779actin binding5.87e-011.00e+000.19117275
GO:0007165signal transduction5.90e-011.00e+00-0.013317950
GO:0006954inflammatory response6.06e-011.00e+000.11916289
GO:0005789endoplasmic reticulum membrane6.07e-011.00e+00-0.019210636
GO:0016567protein ubiquitination6.18e-011.00e+000.07015299
GO:0005743mitochondrial inner membrane6.19e-011.00e+000.06515300
GO:0043231intracellular membrane-bounded organelle6.57e-011.00e+00-0.08118332
GO:0007275multicellular organismal development6.70e-011.00e+00-0.13215344
GO:0008270zinc ion binding6.70e-011.00e+00-0.1803121067
GO:0007155cell adhesion7.11e-011.00e+00-0.29118384
GO:0008284positive regulation of cell proliferation7.18e-011.00e+00-0.32118392
GO:0006508proteolysis7.34e-011.00e+00-0.38519410
GO:0009986cell surface7.44e-011.00e+00-0.42719422
GO:0045892negative regulation of transcription, DNA-templated7.46e-011.00e+00-0.434114424
GO:0045893positive regulation of transcription, DNA-templated7.94e-011.00e+00-0.634117487
GO:0003677DNA binding8.16e-011.00e+00-0.5213261351
GO:0005886plasma membrane8.22e-011.00e+00-0.3677382834
GO:0005615extracellular space8.41e-011.00e+00-0.6862171010
GO:0000122negative regulation of transcription from RNA polymerase II promoter8.53e-011.00e+00-0.908112589
GO:0042803protein homodimerization activity8.66e-011.00e+00-0.975111617
GO:0006351transcription, DNA-templated8.92e-011.00e+00-0.7513251585
GO:0003700sequence-specific DNA binding transcription factor activity9.13e-011.00e+00-1.253111748
GO:0006355regulation of transcription, DNA-templated9.74e-011.00e+00-1.8151171104
GO:0016021integral component of membrane9.98e-011.00e+00-1.9842152483