int-snw-5743

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.944 7.33e-16 2.03e-03 3.48e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-5743 subnetwork

Genes (12)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RPA2 6118 981.2501.15169Yes-
[ PTGS2 ] 5743 1-0.2420.94414-Yes
EIF2S2 8894 271.0751.13881Yes-
PSMD1 5707 120.8361.057113Yes-
RBX1 9978 971.1851.151139Yes-
PSMA2 5683 601.0931.10689Yes-
PSMD3 5709 570.9861.106146Yes-
PSMB7 5695 480.9821.05257Yes-
TP53 7157 20.4320.944564--
PSMA1 5682 610.9961.052123Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-

Interactions (27)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PTGS2 5743 TP53 7157 pp -- int.I2D: BioGrid, BIND, HPRD;
int.HPRD: in vivo
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TP53 7157 EIF2S2 8894 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PTGS2 5743 RBX1 9978 pp -- int.I2D: BioGrid
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 TP53 7157 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RPA2 6118 TP53 7157 pp -- int.Transfac: -
PSMD1 5707 PTGS2 5743 pp -- int.I2D: BioGrid, INNATEDB

Related GO terms (312)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.88e-142.71e-107.03871964
GO:0006521regulation of cellular amino acid metabolic process1.16e-121.67e-087.17261750
GO:0000502proteasome complex2.94e-124.24e-086.95861758
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.98e-128.63e-086.79462265
GO:0000082G1/S transition of mitotic cell cycle8.27e-121.19e-075.819732149
GO:0042981regulation of apoptotic process8.67e-121.25e-075.810724150
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.48e-121.37e-076.68762270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.13e-111.63e-076.64662072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.34e-111.93e-076.60762274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.45e-112.10e-076.58762075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.00e-112.89e-076.51262379
GO:0002474antigen processing and presentation of peptide antigen via MHC class I5.12e-117.38e-076.29362192
GO:0000209protein polyubiquitination2.11e-103.04e-065.958620116
GO:0005654nucleoplasm3.12e-104.50e-063.47410761082
GO:0016032viral process1.46e-092.10e-054.170855534
GO:0034641cellular nitrogen compound metabolic process2.22e-093.20e-055.398620171
GO:0000278mitotic cell cycle7.19e-091.04e-044.427748391
GO:0016071mRNA metabolic process1.09e-081.58e-045.015631223
GO:0043066negative regulation of apoptotic process1.26e-081.82e-044.311731424
GO:0016070RNA metabolic process2.01e-082.90e-044.868632247
GO:0006915apoptotic process8.06e-081.16e-033.922733555
GO:0005838proteasome regulatory particle9.64e-081.39e-038.2313712
GO:0010467gene expression2.89e-074.17e-033.653759669
GO:0022624proteasome accessory complex2.97e-074.29e-037.7293817
GO:0005839proteasome core complex3.57e-075.14e-037.6463818
GO:0004298threonine-type endopeptidase activity4.23e-076.10e-037.5683819
GO:0005829cytosol1.11e-061.61e-022.268101322496
GO:0044281small molecule metabolic process1.57e-052.27e-012.7967581211
GO:0019773proteasome core complex, alpha-subunit complex1.77e-052.56e-018.231248
GO:0031571mitotic G1 DNA damage checkpoint3.48e-055.01e-017.7722411
GO:0030234enzyme regulator activity4.92e-057.10e-017.5312313
GO:0071456cellular response to hypoxia5.30e-057.64e-015.2933692
GO:0042176regulation of protein catabolic process7.57e-051.00e+007.2312316
GO:0034644cellular response to UV2.72e-041.00e+006.3242530
GO:0031625ubiquitin protein ligase binding3.75e-041.00e+004.340314178
GO:0006284base-excision repair4.16e-041.00e+006.0222337
GO:0003684damaged DNA binding7.30e-041.00e+005.6162749
GO:0090271positive regulation of fibroblast growth factor production8.32e-041.00e+0010.231111
GO:0090362positive regulation of platelet-derived growth factor production8.32e-041.00e+0010.231111
GO:0035633maintenance of blood-brain barrier8.32e-041.00e+0010.231111
GO:0050473arachidonate 15-lipoxygenase activity8.32e-041.00e+0010.231111
GO:0006302double-strand break repair1.17e-031.00e+005.2772462
GO:0019903protein phosphatase binding1.17e-031.00e+005.2772462
GO:0070062extracellular vesicular exosome1.27e-031.00e+001.81071042400
GO:0019899enzyme binding1.36e-031.00e+003.702312277
GO:0006289nucleotide-excision repair1.40e-031.00e+005.14421168
GO:0043234protein complex1.62e-031.00e+003.612318295
GO:0097252oligodendrocyte apoptotic process1.66e-031.00e+009.231112
GO:0009750response to fructose1.66e-031.00e+009.231112
GO:0032227negative regulation of synaptic transmission, dopaminergic1.66e-031.00e+009.231112
GO:1901525negative regulation of macromitophagy1.66e-031.00e+009.231112
GO:0002176male germ cell proliferation1.66e-031.00e+009.231112
GO:0090343positive regulation of cell aging1.66e-031.00e+009.231112
GO:0004666prostaglandin-endoperoxide synthase activity1.66e-031.00e+009.231112
GO:0047485protein N-terminus binding2.23e-031.00e+004.8052586
GO:0016605PML body2.33e-031.00e+004.7722388
GO:0035794positive regulation of mitochondrial membrane permeability2.49e-031.00e+008.646113
GO:0051097negative regulation of helicase activity2.49e-031.00e+008.646113
GO:0005850eukaryotic translation initiation factor 2 complex2.49e-031.00e+008.646113
GO:0035033histone deacetylase regulator activity2.49e-031.00e+008.646113
GO:0006928cellular component movement2.49e-031.00e+004.7232791
GO:0002360T cell lineage commitment2.49e-031.00e+008.646123
GO:0034103regulation of tissue remodeling2.49e-031.00e+008.646113
GO:0090336positive regulation of brown fat cell differentiation2.49e-031.00e+008.646113
GO:0019788NEDD8 ligase activity3.32e-031.00e+008.231114
GO:0090403oxidative stress-induced premature senescence3.32e-031.00e+008.231114
GO:0002326B cell lineage commitment3.32e-031.00e+008.231124
GO:0031467Cul7-RING ubiquitin ligase complex3.32e-031.00e+008.231114
GO:0031465Cul4B-RING E3 ubiquitin ligase complex4.15e-031.00e+007.909135
GO:0010666positive regulation of cardiac muscle cell apoptotic process4.15e-031.00e+007.909115
GO:0031622positive regulation of fever generation4.15e-031.00e+007.909125
GO:2000001regulation of DNA damage checkpoint4.15e-031.00e+007.909115
GO:0071636positive regulation of transforming growth factor beta production4.15e-031.00e+007.909115
GO:0097371MDM2/MDM4 family protein binding4.15e-031.00e+007.909115
GO:0045986negative regulation of smooth muscle contraction4.15e-031.00e+007.909115
GO:0031461cullin-RING ubiquitin ligase complex4.15e-031.00e+007.909115
GO:0043248proteasome assembly4.15e-031.00e+007.909115
GO:0031915positive regulation of synaptic plasticity4.15e-031.00e+007.909125
GO:0030891VCB complex4.15e-031.00e+007.909125
GO:0070245positive regulation of thymocyte apoptotic process4.15e-031.00e+007.909115
GO:0000730DNA recombinase assembly4.15e-031.00e+007.909115
GO:0031394positive regulation of prostaglandin biosynthetic process4.15e-031.00e+007.909115
GO:0007219Notch signaling pathway4.29e-031.00e+004.32425120
GO:0000790nuclear chromatin4.94e-031.00e+004.22029129
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process4.98e-031.00e+007.646116
GO:0002309T cell proliferation involved in immune response4.98e-031.00e+007.646116
GO:0010042response to manganese ion4.98e-031.00e+007.646116
GO:0031466Cul5-RING ubiquitin ligase complex4.98e-031.00e+007.646116
GO:0030957Tat protein binding4.98e-031.00e+007.646136
GO:0007406negative regulation of neuroblast proliferation4.98e-031.00e+007.646116
GO:0030728ovulation5.81e-031.00e+007.424117
GO:0000733DNA strand renaturation5.81e-031.00e+007.424117
GO:0090050positive regulation of cell migration involved in sprouting angiogenesis5.81e-031.00e+007.424117
GO:0031462Cul2-RING ubiquitin ligase complex5.81e-031.00e+007.424127
GO:0031497chromatin assembly5.81e-031.00e+007.424117
GO:0031464Cul4A-RING E3 ubiquitin ligase complex6.64e-031.00e+007.231128
GO:0042633hair cycle6.64e-031.00e+007.231118
GO:0070688MLL5-L complex6.64e-031.00e+007.231118
GO:0045116protein neddylation6.64e-031.00e+007.231128
GO:0019372lipoxygenase pathway7.47e-031.00e+007.061119
GO:0006693prostaglandin metabolic process7.47e-031.00e+007.061119
GO:0006983ER overload response7.47e-031.00e+007.061129
GO:0031065positive regulation of histone deacetylation7.47e-031.00e+007.061119
GO:0005730nucleolus7.54e-031.00e+001.8735691641
GO:0010569regulation of double-strand break repair via homologous recombination8.29e-031.00e+006.9091110
GO:0071850mitotic cell cycle arrest8.29e-031.00e+006.9091110
GO:0010226response to lithium ion8.29e-031.00e+006.9091210
GO:0090399replicative senescence8.29e-031.00e+006.9091110
GO:0071318cellular response to ATP8.29e-031.00e+006.9091110
GO:0046902regulation of mitochondrial membrane permeability8.29e-031.00e+006.9091210
GO:0008340determination of adult lifespan9.12e-031.00e+006.7721111
GO:0009303rRNA transcription9.12e-031.00e+006.7721111
GO:0001516prostaglandin biosynthetic process9.94e-031.00e+006.6461112
GO:0051926negative regulation of calcium ion transport9.94e-031.00e+006.6461112
GO:0070266necroptotic process9.94e-031.00e+006.6461112
GO:0032461positive regulation of protein oligomerization9.94e-031.00e+006.6461112
GO:0019371cyclooxygenase pathway9.94e-031.00e+006.6461112
GO:0005662DNA replication factor A complex1.08e-021.00e+006.5311113
GO:0035267NuA4 histone acetyltransferase complex1.16e-021.00e+006.4241414
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator1.16e-021.00e+006.4241214
GO:2000378negative regulation of reactive oxygen species metabolic process1.16e-021.00e+006.4241114
GO:0033280response to vitamin D1.16e-021.00e+006.4241114
GO:0001701in utero embryonic development1.16e-021.00e+003.58028201
GO:0030330DNA damage response, signal transduction by p53 class mediator1.16e-021.00e+006.4241114
GO:0070542response to fatty acid1.16e-021.00e+006.4241114
GO:0009651response to salt stress1.16e-021.00e+006.4241214
GO:0048568embryonic organ development1.16e-021.00e+006.4241114
GO:0045987positive regulation of smooth muscle contraction1.24e-021.00e+006.3241115
GO:0051968positive regulation of synaptic transmission, glutamatergic1.32e-021.00e+006.2311116
GO:0050998nitric-oxide synthase binding1.32e-021.00e+006.2311116
GO:0005634nucleus1.33e-021.00e+001.07781364559
GO:0042149cellular response to glucose starvation1.41e-021.00e+006.1441117
GO:0051721protein phosphatase 2A binding1.41e-021.00e+006.1441117
GO:0035861site of double-strand break1.49e-021.00e+006.0611118
GO:0046697decidualization1.49e-021.00e+006.0611118
GO:0005657replication fork1.49e-021.00e+006.0611318
GO:0042346positive regulation of NF-kappaB import into nucleus1.49e-021.00e+006.0611218
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.57e-021.00e+005.9831119
GO:0048863stem cell differentiation1.57e-021.00e+005.9831119
GO:0035035histone acetyltransferase binding1.57e-021.00e+005.9831119
GO:0007369gastrulation1.57e-021.00e+005.9831119
GO:0071158positive regulation of cell cycle arrest1.57e-021.00e+005.9831219
GO:0010165response to X-ray1.57e-021.00e+005.9831319
GO:0004601peroxidase activity1.57e-021.00e+005.9831119
GO:0008156negative regulation of DNA replication1.65e-021.00e+005.9091120
GO:0002931response to ischemia1.65e-021.00e+005.9091120
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator1.65e-021.00e+005.9091220
GO:0006298mismatch repair1.65e-021.00e+005.9091320
GO:0010575positive regulation vascular endothelial growth factor production1.73e-021.00e+005.8391121
GO:0000718nucleotide-excision repair, DNA damage removal1.73e-021.00e+005.8391421
GO:0032201telomere maintenance via semi-conservative replication1.73e-021.00e+005.8391521
GO:0005669transcription factor TFIID complex1.82e-021.00e+005.7721122
GO:0090200positive regulation of release of cytochrome c from mitochondria1.82e-021.00e+005.7721122
GO:0045907positive regulation of vasoconstriction1.82e-021.00e+005.7721122
GO:0006297nucleotide-excision repair, DNA gap filling1.82e-021.00e+005.7721322
GO:0048147negative regulation of fibroblast proliferation1.82e-021.00e+005.7721122
GO:0030863cortical cytoskeleton1.82e-021.00e+005.7721122
GO:0036464cytoplasmic ribonucleoprotein granule1.82e-021.00e+005.7721422
GO:0031463Cul3-RING ubiquitin ligase complex1.90e-021.00e+005.7081323
GO:0006513protein monoubiquitination1.90e-021.00e+005.7081123
GO:0043044ATP-dependent chromatin remodeling1.90e-021.00e+005.7081423
GO:0005844polysome1.90e-021.00e+005.7081423
GO:0071479cellular response to ionizing radiation1.90e-021.00e+005.7081123
GO:2000379positive regulation of reactive oxygen species metabolic process1.90e-021.00e+005.7081223
GO:0006281DNA repair1.91e-021.00e+003.203218261
GO:0008135translation factor activity, nucleic acid binding1.98e-021.00e+005.6461724
GO:0001836release of cytochrome c from mitochondria1.98e-021.00e+005.6461324
GO:0000060protein import into nucleus, translocation1.98e-021.00e+005.6461524
GO:0043065positive regulation of apoptotic process2.01e-021.00e+003.165210268
GO:0000722telomere maintenance via recombination2.06e-021.00e+005.5871525
GO:0007569cell aging2.06e-021.00e+005.5871125
GO:0005515protein binding2.09e-021.00e+000.84591846024
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway2.14e-021.00e+005.5311426
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.14e-021.00e+005.5311326
GO:0034612response to tumor necrosis factor2.22e-021.00e+005.4761227
GO:0031492nucleosomal DNA binding2.22e-021.00e+005.4761427
GO:0010332response to gamma radiation2.31e-021.00e+005.4241328
GO:0019894kinesin binding2.31e-021.00e+005.4241128
GO:0030282bone mineralization2.39e-021.00e+005.3731129
GO:0019005SCF ubiquitin ligase complex2.39e-021.00e+005.3731129
GO:0050873brown fat cell differentiation2.39e-021.00e+005.3731229
GO:0021549cerebellum development2.39e-021.00e+005.3731129
GO:0051262protein tetramerization2.47e-021.00e+005.3241230
GO:0006271DNA strand elongation involved in DNA replication2.47e-021.00e+005.3241730
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2.47e-021.00e+005.3241230
GO:0046677response to antibiotic2.55e-021.00e+005.2771231
GO:0016604nuclear body2.55e-021.00e+005.2771231
GO:0001756somitogenesis2.71e-021.00e+005.1871233
GO:0030971receptor tyrosine kinase binding2.71e-021.00e+005.1871233
GO:0033077T cell differentiation in thymus2.71e-021.00e+005.1871233
GO:2001244positive regulation of intrinsic apoptotic signaling pathway2.71e-021.00e+005.1871233
GO:0001085RNA polymerase II transcription factor binding2.71e-021.00e+005.1871233
GO:0019901protein kinase binding2.75e-021.00e+002.923221317
GO:0001895retina homeostasis2.79e-021.00e+005.1441134
GO:0007566embryo implantation2.87e-021.00e+005.1021135
GO:0045429positive regulation of nitric oxide biosynthetic process2.87e-021.00e+005.1021335
GO:0034332adherens junction organization2.96e-021.00e+005.0611136
GO:0051402neuron apoptotic process2.96e-021.00e+005.0611236
GO:0051084'de novo' posttranslational protein folding3.04e-021.00e+005.0221437
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.04e-021.00e+005.0221237
GO:0070527platelet aggregation3.12e-021.00e+004.9831238
GO:0003723RNA binding3.16e-021.00e+002.813220342
GO:0000781chromosome, telomeric region3.20e-021.00e+004.9461339
GO:0045786negative regulation of cell cycle3.20e-021.00e+004.9461139
GO:0008285negative regulation of cell proliferation3.35e-021.00e+002.768211353
GO:0019369arachidonic acid metabolic process3.44e-021.00e+004.8391242
GO:0021762substantia nigra development3.60e-021.00e+004.7721244
GO:0034613cellular protein localization3.60e-021.00e+004.7721144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding3.60e-021.00e+004.7721244
GO:0007612learning3.68e-021.00e+004.7391145
GO:0050727regulation of inflammatory response3.68e-021.00e+004.7391345
GO:0043525positive regulation of neuron apoptotic process3.76e-021.00e+004.7081246
GO:0006283transcription-coupled nucleotide-excision repair3.76e-021.00e+004.7081746
GO:0005507copper ion binding3.76e-021.00e+004.7081246
GO:0019233sensory perception of pain3.92e-021.00e+004.6461148
GO:0003743translation initiation factor activity4.00e-021.00e+004.6161849
GO:0048661positive regulation of smooth muscle cell proliferation4.00e-021.00e+004.6161449
GO:0035690cellular response to drug4.00e-021.00e+004.6161249
GO:0016020membrane4.22e-021.00e+001.5164901681
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding4.32e-021.00e+004.5031553
GO:0007613memory4.32e-021.00e+004.5031153
GO:0045216cell-cell junction organization4.40e-021.00e+004.4761254
GO:0000932cytoplasmic mRNA processing body4.40e-021.00e+004.4761354
GO:0097193intrinsic apoptotic signaling pathway4.48e-021.00e+004.4501655
GO:0002039p53 binding4.48e-021.00e+004.4501755
GO:0000724double-strand break repair via homologous recombination4.48e-021.00e+004.4501355
GO:0008104protein localization4.56e-021.00e+004.4241356
GO:0000723telomere maintenance4.56e-021.00e+004.4241656
GO:0008217regulation of blood pressure4.64e-021.00e+004.3981457
GO:0051087chaperone binding4.80e-021.00e+004.3481659
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway4.96e-021.00e+004.3001261
GO:0005901caveola5.04e-021.00e+004.2771562
GO:0051384response to glucocorticoid5.04e-021.00e+004.2771262
GO:0071260cellular response to mechanical stimulus5.28e-021.00e+004.2091565
GO:0007596blood coagulation5.32e-021.00e+002.401218455
GO:0035264multicellular organism growth5.44e-021.00e+004.1651167
GO:0003697single-stranded DNA binding5.52e-021.00e+004.1441568
GO:0034329cell junction assembly5.52e-021.00e+004.1441168
GO:0044267cellular protein metabolic process5.72e-021.00e+002.342229474
GO:0032355response to estradiol5.75e-021.00e+004.0811571
GO:0000785chromatin5.91e-021.00e+004.0411473
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis5.99e-021.00e+004.0221674
GO:0002020protease binding5.99e-021.00e+004.0221474
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process6.07e-021.00e+004.0021275
GO:0008584male gonad development6.07e-021.00e+004.0021375
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation6.07e-021.00e+004.0021375
GO:0007265Ras protein signal transduction6.07e-021.00e+004.0021275
GO:0006979response to oxidative stress7.01e-021.00e+003.7881387
GO:0016363nuclear matrix7.32e-021.00e+003.72311291
GO:0005200structural constituent of cytoskeleton7.32e-021.00e+003.7231891
GO:0020037heme binding7.47e-021.00e+003.6921293
GO:0014069postsynaptic density8.40e-021.00e+003.51713105
GO:0008289lipid binding8.47e-021.00e+003.50311106
GO:0030308negative regulation of cell growth8.78e-021.00e+003.45016110
GO:0015630microtubule cytoskeleton8.78e-021.00e+003.45014110
GO:0006461protein complex assembly8.86e-021.00e+003.43716111
GO:0072562blood microparticle8.86e-021.00e+003.43713111
GO:0030529ribonucleoprotein complex8.93e-021.00e+003.42418112
GO:0006325chromatin organization9.39e-021.00e+003.34815118
GO:0032496response to lipopolysaccharide9.62e-021.00e+003.31214121
GO:0006260DNA replication9.62e-021.00e+003.31219121
GO:0007050cell cycle arrest9.85e-021.00e+003.27719124
GO:0009615response to virus1.00e-011.00e+003.25415126
GO:0006511ubiquitin-dependent protein catabolic process1.00e-011.00e+003.25415126
GO:0007179transforming growth factor beta receptor signaling pathway1.01e-011.00e+003.23114128
GO:0006413translational initiation1.04e-011.00e+003.198117131
GO:0006457protein folding1.13e-011.00e+003.07117143
GO:0061024membrane organization1.14e-011.00e+003.05117145
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.16e-011.00e+003.03113147
GO:0006974cellular response to DNA damage stimulus1.19e-011.00e+002.99318151
GO:0043005neuron projection1.23e-011.00e+002.93716157
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.29e-011.00e+002.86517165
GO:0030424axon1.30e-011.00e+002.85614166
GO:0044212transcription regulatory region DNA binding1.31e-011.00e+002.83916168
GO:0032403protein complex binding1.42e-011.00e+002.715110183
GO:0001525angiogenesis1.48e-011.00e+002.65414191
GO:0005759mitochondrial matrix1.74e-011.00e+002.398114228
GO:0006412translation1.75e-011.00e+002.386120230
GO:0008134transcription factor binding1.84e-011.00e+002.31218242
GO:0004842ubiquitin-protein transferase activity1.93e-011.00e+002.23716255
GO:0008270zinc ion binding1.99e-011.00e+001.270212997
GO:0006954inflammatory response2.08e-011.00e+002.11717277
GO:0042493response to drug2.12e-011.00e+002.081113284
GO:0005856cytoskeleton2.17e-011.00e+002.046112291
GO:0016567protein ubiquitination2.20e-011.00e+002.02715295
GO:0030154cell differentiation2.24e-011.00e+001.99815301
GO:0007275multicellular organismal development2.34e-011.00e+001.92715316
GO:0007411axon guidance2.35e-011.00e+001.914113319
GO:0005813centrosome2.40e-011.00e+001.882114326
GO:0008283cell proliferation2.41e-011.00e+001.874114328
GO:0003682chromatin binding2.41e-011.00e+001.878111327
GO:0005925focal adhesion2.65e-011.00e+001.715119366
GO:0046982protein heterodimerization activity2.74e-011.00e+001.661113380
GO:0045892negative regulation of transcription, DNA-templated2.94e-011.00e+001.541115413
GO:0005524ATP binding2.95e-011.00e+000.8892601298
GO:0046872metal ion binding2.98e-011.00e+000.8792251307
GO:0055114oxidation-reduction process2.99e-011.00e+001.517112420
GO:0045893positive regulation of transcription, DNA-templated3.33e-011.00e+001.330113478
GO:0042802identical protein binding3.36e-011.00e+001.312120484
GO:0005783endoplasmic reticulum3.76e-011.00e+001.112110556
GO:0005789endoplasmic reticulum membrane3.84e-011.00e+001.076116570
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.84e-011.00e+001.076116570
GO:0005737cytoplasm3.86e-011.00e+000.35241103767
GO:0042803protein homodimerization activity3.97e-011.00e+001.014112595
GO:0045087innate immune response3.97e-011.00e+001.012124596
GO:0003700sequence-specific DNA binding transcription factor activity4.49e-011.00e+000.782111699
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.91e-011.00e+000.607119789
GO:0005615extracellular space5.61e-011.00e+000.329117957
GO:0006355regulation of transcription, DNA-templated5.77e-011.00e+000.270118997
GO:0005739mitochondrion5.77e-011.00e+000.268128998
GO:0044822poly(A) RNA binding5.99e-011.00e+000.1871491056
GO:0003677DNA binding6.53e-011.00e+00-0.0191281218