TP53

Genes (1)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
TP53 7157 20.4320.944564--

Gene info in the NCBI database: TP53

Subnetworks (2)

Subnetwork ID wolf-screen-ratio-mammosphere-adherent score Size Highlighted genes
int-snw-5743 0.944 12 11
int-snw-3838 0.930 10 8

Related GO terms (137)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005515protein binding1846024
GO:0045892negative regulation of transcription, DNA-templated15413
GO:0051262protein tetramerization230
GO:2001244positive regulation of intrinsic apoptotic signaling pathway233
GO:0003682chromatin binding11327
GO:0030308negative regulation of cell growth6110
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation375
GO:2000379positive regulation of reactive oxygen species metabolic process223
GO:0090343positive regulation of cell aging12
GO:0019903protein phosphatase binding462
GO:0034103regulation of tissue remodeling13
GO:0000060protein import into nucleus, translocation524
GO:0003700sequence-specific DNA binding transcription factor activity11699
GO:0010165response to X-ray319
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription237
GO:0008104protein localization356
GO:0016604nuclear body231
GO:1901525negative regulation of macromitophagy12
GO:0005669transcription factor TFIID complex122
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator220
GO:0002039p53 binding755
GO:0044212transcription regulatory region DNA binding6168
GO:0002931response to ischemia120
GO:0035264multicellular organism growth167
GO:0090399replicative senescence110
GO:0007275multicellular organismal development5316
GO:0007265Ras protein signal transduction275
GO:0070245positive regulation of thymocyte apoptotic process15
GO:0006461protein complex assembly6111
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process16
GO:0005759mitochondrial matrix14228
GO:0035035histone acetyltransferase binding119
GO:0097252oligodendrocyte apoptotic process12
GO:0001085RNA polymerase II transcription factor binding233
GO:0008283cell proliferation14328
GO:0071456cellular response to hypoxia692
GO:0048568embryonic organ development114
GO:0003684damaged DNA binding749
GO:0001756somitogenesis233
GO:0009651response to salt stress214
GO:0002326B cell lineage commitment24
GO:0009303rRNA transcription111
GO:0031065positive regulation of histone deacetylation19
GO:0019901protein kinase binding21317
GO:0006355regulation of transcription, DNA-templated18997
GO:0097193intrinsic apoptotic signaling pathway655
GO:0016605PML body388
GO:0010332response to gamma radiation328
GO:0000790nuclear chromatin9129
GO:0007050cell cycle arrest9124
GO:0005657replication fork318
GO:0005654nucleoplasm761082
GO:0030971receptor tyrosine kinase binding233
GO:0035033histone deacetylase regulator activity13
GO:0030330DNA damage response, signal transduction by p53 class mediator114
GO:0046677response to antibiotic231
GO:0016032viral process55534
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator214
GO:0007369gastrulation119
GO:0002020protease binding474
GO:2000378negative regulation of reactive oxygen species metabolic process114
GO:0071850mitotic cell cycle arrest110
GO:0071158positive regulation of cell cycle arrest219
GO:0043234protein complex18295
GO:0005634nucleus1364559
GO:0034644cellular response to UV530
GO:0001701in utero embryonic development8201
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding244
GO:0042802identical protein binding20484
GO:0005737cytoplasm1103767
GO:0000733DNA strand renaturation17
GO:0006974cellular response to DNA damage stimulus8151
GO:0021549cerebellum development129
GO:0006284base-excision repair337
GO:0031625ubiquitin protein ligase binding14178
GO:0005783endoplasmic reticulum10556
GO:0008340determination of adult lifespan111
GO:0005829cytosol1322496
GO:0043066negative regulation of apoptotic process31424
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator230
GO:0002360T cell lineage commitment23
GO:0005739mitochondrion28998
GO:0008156negative regulation of DNA replication120
GO:0035794positive regulation of mitochondrial membrane permeability13
GO:0045893positive regulation of transcription, DNA-templated13478
GO:0008285negative regulation of cell proliferation11353
GO:0010666positive regulation of cardiac muscle cell apoptotic process15
GO:0035690cellular response to drug249
GO:0016363nuclear matrix1291
GO:0042981regulation of apoptotic process24150
GO:0042149cellular response to glucose starvation117
GO:0000785chromatin473
GO:0002309T cell proliferation involved in immune response16
GO:0007179transforming growth factor beta receptor signaling pathway4128
GO:0005524ATP binding601298
GO:0045944positive regulation of transcription from RNA polymerase II promoter19789
GO:0051097negative regulation of helicase activity13
GO:0006983ER overload response29
GO:0031497chromatin assembly17
GO:0090403oxidative stress-induced premature senescence14
GO:0006302double-strand break repair462
GO:0031571mitotic G1 DNA damage checkpoint411
GO:0033077T cell differentiation in thymus233
GO:0006915apoptotic process33555
GO:0046902regulation of mitochondrial membrane permeability210
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1964
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway261
GO:0006289nucleotide-excision repair1168
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3147
GO:0030154cell differentiation5301
GO:0051402neuron apoptotic process236
GO:0046982protein heterodimerization activity13380
GO:0007406negative regulation of neuroblast proliferation16
GO:0032461positive regulation of protein oligomerization112
GO:0051721protein phosphatase 2A binding117
GO:0007596blood coagulation18455
GO:0005730nucleolus691641
GO:0001836release of cytochrome c from mitochondria324
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway426
GO:0047485protein N-terminus binding586
GO:0070266necroptotic process112
GO:0071479cellular response to ionizing radiation123
GO:0051087chaperone binding659
GO:0008270zinc ion binding12997
GO:0005507copper ion binding246
GO:0043065positive regulation of apoptotic process10268
GO:0007219Notch signaling pathway5120
GO:0097371MDM2/MDM4 family protein binding15
GO:0043525positive regulation of neuron apoptotic process246
GO:0048147negative regulation of fibroblast proliferation122
GO:0090200positive regulation of release of cytochrome c from mitochondria122
GO:0000122negative regulation of transcription from RNA polymerase II promoter16570
GO:0003677DNA binding281218
GO:0007569cell aging125
GO:0019899enzyme binding12277
GO:0008134transcription factor binding8242
GO:0034613cellular protein localization144