int-snw-3838

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.930 2.46e-15 2.73e-03 4.30e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-3838 subnetwork

Genes (10)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RPA2 6118 981.2501.15169Yes-
EIF2S2 8894 271.0751.13881Yes-
PSMA2 5683 601.0931.10689Yes-
HNRNPC 3183 201.8121.026119Yes-
TP53 7157 20.4320.944564--
ACTB 60 1671.1531.151587Yes-
PSMD11 5717 1211.0951.106183Yes-
[ KPNA2 ] 3838 10.1760.930141--
KPNB1 3837 60.6131.017296Yes-
ITK 3702 20.6020.95039Yes-

Interactions (14)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
KPNB1 3837 PSMA2 5683 pp -- int.I2D: Krogan_NonCore, YeastLow
ACTB 60 KPNB1 3837 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
KPNB1 3837 KPNA2 3838 pp -- int.I2D: BioGrid, BIND_Mouse, IntAct_Fly, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro, yeast 2-hybrid;
int.DIP: MI:0407(direct interaction)
KPNB1 3837 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
PSMD11 5717 TP53 7157 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
KPNB1 3837 TP53 7157 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vivo
RPA2 6118 TP53 7157 pp -- int.Transfac: -
ITK 3702 KPNA2 3838 pp -- int.I2D: BioGrid, HPRD, BIND;
int.HPRD: in vitro, in vivo
KPNA2 3838 TP53 7157 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
HNRNPC 3183 KPNA2 3838 pp -- int.Intact: MI:0915(physical association)
TP53 7157 EIF2S2 8894 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid

Related GO terms (272)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm3.84e-085.54e-043.4158761082
GO:0005829cytosol1.16e-061.68e-022.37991322496
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest9.78e-061.41e-016.07931964
GO:0016032viral process1.47e-052.13e-013.755555534
GO:0008139nuclear localization sequence binding1.55e-052.24e-018.324239
GO:0031571mitotic G1 DNA damage checkpoint2.37e-053.42e-018.0352411
GO:0006607NLS-bearing protein import into nucleus3.92e-055.65e-017.6872314
GO:0000790nuclear chromatin8.01e-051.00e+005.06839129
GO:0043044ATP-dependent chromatin remodeling1.09e-041.00e+006.9712423
GO:0000060protein import into nucleus, translocation1.18e-041.00e+006.9092524
GO:0000082G1/S transition of mitotic cell cycle1.23e-041.00e+004.860332149
GO:0042981regulation of apoptotic process1.25e-041.00e+004.850324150
GO:0031492nucleosomal DNA binding1.50e-041.00e+006.7392427
GO:0005515protein binding1.61e-041.00e+001.260101846024
GO:0006284base-excision repair2.84e-041.00e+006.2852337
GO:0006915apoptotic process3.78e-041.00e+003.378433555
GO:0003684damaged DNA binding5.00e-041.00e+005.8792749
GO:0006521regulation of cellular amino acid metabolic process5.21e-041.00e+005.85021750
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.85e-041.00e+005.7662553
GO:0008565protein transporter activity6.53e-041.00e+005.6872556
GO:0000502proteasome complex7.01e-041.00e+005.63621758
GO:0019899enzyme binding7.61e-041.00e+003.965312277
GO:0010467gene expression7.70e-041.00e+003.108459669
GO:0006302double-strand break repair8.00e-041.00e+005.5402462
GO:0019903protein phosphatase binding8.00e-041.00e+005.5402462
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.79e-041.00e+005.47222265
GO:0043234protein complex9.14e-041.00e+003.875318295
GO:0006289nucleotide-excision repair9.62e-041.00e+005.40721168
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.02e-031.00e+005.36522270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.08e-031.00e+005.32422072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.14e-031.00e+005.28522274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.17e-031.00e+005.26522075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.30e-031.00e+005.19022379
GO:0097252oligodendrocyte apoptotic process1.39e-031.00e+009.494112
GO:1901525negative regulation of macromitophagy1.39e-031.00e+009.494112
GO:0002176male germ cell proliferation1.39e-031.00e+009.494112
GO:0032633interleukin-4 production1.39e-031.00e+009.494112
GO:0090343positive regulation of cell aging1.39e-031.00e+009.494112
GO:0001865NK T cell differentiation1.39e-031.00e+009.494112
GO:0047485protein N-terminus binding1.53e-031.00e+005.0682586
GO:0016605PML body1.60e-031.00e+005.0352388
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.75e-031.00e+004.97122192
GO:0000278mitotic cell cycle2.06e-031.00e+003.468348391
GO:0035794positive regulation of mitochondrial membrane permeability2.08e-031.00e+008.909113
GO:0051097negative regulation of helicase activity2.08e-031.00e+008.909113
GO:0005850eukaryotic translation initiation factor 2 complex2.08e-031.00e+008.909113
GO:0035033histone deacetylase regulator activity2.08e-031.00e+008.909113
GO:0002360T cell lineage commitment2.08e-031.00e+008.909123
GO:0034103regulation of tissue remodeling2.08e-031.00e+008.909113
GO:0043066negative regulation of apoptotic process2.59e-031.00e+003.351331424
GO:0000209protein polyubiquitination2.77e-031.00e+004.636220116
GO:0090403oxidative stress-induced premature senescence2.77e-031.00e+008.494114
GO:0002326B cell lineage commitment2.77e-031.00e+008.494124
GO:0006610ribosomal protein import into nucleus2.77e-031.00e+008.494114
GO:0071782endoplasmic reticulum tubular network2.77e-031.00e+008.494114
GO:0005730nucleolus2.92e-031.00e+002.1365691641
GO:0016020membrane3.25e-031.00e+002.1015901681
GO:0010666positive regulation of cardiac muscle cell apoptotic process3.46e-031.00e+008.172115
GO:2000001regulation of DNA damage checkpoint3.46e-031.00e+008.172115
GO:0097371MDM2/MDM4 family protein binding3.46e-031.00e+008.172115
GO:0043248proteasome assembly3.46e-031.00e+008.172115
GO:0070245positive regulation of thymocyte apoptotic process3.46e-031.00e+008.172115
GO:0000730DNA recombinase assembly3.46e-031.00e+008.172115
GO:0000018regulation of DNA recombination4.15e-031.00e+007.909116
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process4.15e-031.00e+007.909116
GO:0002309T cell proliferation involved in immune response4.15e-031.00e+007.909116
GO:0030957Tat protein binding4.15e-031.00e+007.909136
GO:0007406negative regulation of neuroblast proliferation4.15e-031.00e+007.909116
GO:0044822poly(A) RNA binding4.19e-031.00e+002.4504491056
GO:0000733DNA strand renaturation4.84e-031.00e+007.687117
GO:0031497chromatin assembly4.84e-031.00e+007.687117
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.51e-031.00e+004.12827165
GO:0070688MLL5-L complex5.53e-031.00e+007.494118
GO:0019773proteasome core complex, alpha-subunit complex5.53e-031.00e+007.494148
GO:0034641cellular nitrogen compound metabolic process5.91e-031.00e+004.076220171
GO:0032609interferon-gamma production6.22e-031.00e+007.324119
GO:0006983ER overload response6.22e-031.00e+007.324129
GO:0031065positive regulation of histone deacetylation6.22e-031.00e+007.324119
GO:0031625ubiquitin protein ligase binding6.39e-031.00e+004.018214178
GO:0010569regulation of double-strand break repair via homologous recombination6.91e-031.00e+007.1721110
GO:0071850mitotic cell cycle arrest6.91e-031.00e+007.1721110
GO:0090399replicative senescence6.91e-031.00e+007.1721110
GO:0046902regulation of mitochondrial membrane permeability6.91e-031.00e+007.1721210
GO:0008340determination of adult lifespan7.60e-031.00e+007.0351111
GO:0045120pronucleus7.60e-031.00e+007.0351211
GO:0009303rRNA transcription7.60e-031.00e+007.0351111
GO:0001701in utero embryonic development8.08e-031.00e+003.84328201
GO:00709353'-UTR-mediated mRNA stabilization8.29e-031.00e+006.9091212
GO:0070266necroptotic process8.29e-031.00e+006.9091112
GO:0032461positive regulation of protein oligomerization8.29e-031.00e+006.9091112
GO:0005838proteasome regulatory particle8.29e-031.00e+006.9091712
GO:0005662DNA replication factor A complex8.98e-031.00e+006.7941113
GO:0008266poly(U) RNA binding8.98e-031.00e+006.7941113
GO:0035267NuA4 histone acetyltransferase complex9.67e-031.00e+006.6871414
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator9.67e-031.00e+006.6871214
GO:2000378negative regulation of reactive oxygen species metabolic process9.67e-031.00e+006.6871114
GO:0030330DNA damage response, signal transduction by p53 class mediator9.67e-031.00e+006.6871114
GO:0009651response to salt stress9.67e-031.00e+006.6871214
GO:0048568embryonic organ development9.67e-031.00e+006.6871114
GO:0019221cytokine-mediated signaling pathway9.70e-031.00e+003.70629221
GO:0016071mRNA metabolic process9.87e-031.00e+003.693231223
GO:0050998nitric-oxide synthase binding1.10e-021.00e+006.4941116
GO:0042149cellular response to glucose starvation1.17e-021.00e+006.4071117
GO:0051721protein phosphatase 2A binding1.17e-021.00e+006.4071117
GO:0075733intracellular transport of virus1.17e-021.00e+006.4071317
GO:0006309apoptotic DNA fragmentation1.17e-021.00e+006.4071117
GO:0022624proteasome accessory complex1.17e-021.00e+006.4071817
GO:0016070RNA metabolic process1.20e-021.00e+003.546232247
GO:0035861site of double-strand break1.24e-021.00e+006.3241118
GO:0005839proteasome core complex1.24e-021.00e+006.3241818
GO:0005657replication fork1.24e-021.00e+006.3241318
GO:0006259DNA metabolic process1.31e-021.00e+006.2461219
GO:0048863stem cell differentiation1.31e-021.00e+006.2461119
GO:0035035histone acetyltransferase binding1.31e-021.00e+006.2461119
GO:0007369gastrulation1.31e-021.00e+006.2461119
GO:0004298threonine-type endopeptidase activity1.31e-021.00e+006.2461819
GO:0071158positive regulation of cell cycle arrest1.31e-021.00e+006.2461219
GO:0010165response to X-ray1.31e-021.00e+006.2461319
GO:0008156negative regulation of DNA replication1.38e-021.00e+006.1721120
GO:0002931response to ischemia1.38e-021.00e+006.1721120
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator1.38e-021.00e+006.1721220
GO:0006298mismatch repair1.38e-021.00e+006.1721320
GO:0005634nucleus1.44e-021.00e+001.14771364559
GO:0000718nucleotide-excision repair, DNA damage removal1.45e-021.00e+006.1021421
GO:0032201telomere maintenance via semi-conservative replication1.45e-021.00e+006.1021521
GO:0005669transcription factor TFIID complex1.52e-021.00e+006.0351122
GO:0090200positive regulation of release of cytochrome c from mitochondria1.52e-021.00e+006.0351122
GO:0006297nucleotide-excision repair, DNA gap filling1.52e-021.00e+006.0351322
GO:0048147negative regulation of fibroblast proliferation1.52e-021.00e+006.0351122
GO:0030863cortical cytoskeleton1.52e-021.00e+006.0351122
GO:0036464cytoplasmic ribonucleoprotein granule1.52e-021.00e+006.0351422
GO:0070062extracellular vesicular exosome1.53e-021.00e+001.58751042400
GO:0071479cellular response to ionizing radiation1.58e-021.00e+005.9711123
GO:2000379positive regulation of reactive oxygen species metabolic process1.58e-021.00e+005.9711223
GO:0008135translation factor activity, nucleic acid binding1.65e-021.00e+005.9091724
GO:0001836release of cytochrome c from mitochondria1.65e-021.00e+005.9091324
GO:0001816cytokine production1.72e-021.00e+005.8501325
GO:0000722telomere maintenance via recombination1.72e-021.00e+005.8501525
GO:0008536Ran GTPase binding1.72e-021.00e+005.8501125
GO:0007569cell aging1.72e-021.00e+005.8501125
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway1.79e-021.00e+005.7941426
GO:0003730mRNA 3'-UTR binding1.79e-021.00e+005.7941226
GO:0019901protein kinase binding1.93e-021.00e+003.186221317
GO:0010332response to gamma radiation1.93e-021.00e+005.6871328
GO:0002250adaptive immune response1.93e-021.00e+005.6871128
GO:0019894kinesin binding1.93e-021.00e+005.6871128
GO:0021549cerebellum development1.99e-021.00e+005.6361129
GO:0006606protein import into nucleus2.06e-021.00e+005.5871230
GO:0051262protein tetramerization2.06e-021.00e+005.5871230
GO:0034644cellular response to UV2.06e-021.00e+005.5871530
GO:0006271DNA strand elongation involved in DNA replication2.06e-021.00e+005.5871730
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2.06e-021.00e+005.5871230
GO:0046677response to antibiotic2.13e-021.00e+005.5401231
GO:0016604nuclear body2.13e-021.00e+005.5401231
GO:0003723RNA binding2.22e-021.00e+003.076220342
GO:0001756somitogenesis2.27e-021.00e+005.4501233
GO:0030971receptor tyrosine kinase binding2.27e-021.00e+005.4501233
GO:0033077T cell differentiation in thymus2.27e-021.00e+005.4501233
GO:2001244positive regulation of intrinsic apoptotic signaling pathway2.27e-021.00e+005.4501233
GO:0001085RNA polymerase II transcription factor binding2.27e-021.00e+005.4501233
GO:0001895retina homeostasis2.33e-021.00e+005.4071134
GO:0034332adherens junction organization2.47e-021.00e+005.3241136
GO:0051402neuron apoptotic process2.47e-021.00e+005.3241236
GO:0051084'de novo' posttranslational protein folding2.54e-021.00e+005.2851437
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.54e-021.00e+005.2851237
GO:0070527platelet aggregation2.60e-021.00e+005.2461238
GO:0000781chromosome, telomeric region2.67e-021.00e+005.2091339
GO:0042110T cell activation2.88e-021.00e+005.1021342
GO:0004715non-membrane spanning protein tyrosine kinase activity2.88e-021.00e+005.1021442
GO:0021762substantia nigra development3.01e-021.00e+005.0351244
GO:0034613cellular protein localization3.01e-021.00e+005.0351144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding3.01e-021.00e+005.0351244
GO:0043525positive regulation of neuron apoptotic process3.14e-021.00e+004.9711246
GO:0006283transcription-coupled nucleotide-excision repair3.14e-021.00e+004.9711746
GO:0005507copper ion binding3.14e-021.00e+004.9711246
GO:0006921cellular component disassembly involved in execution phase of apoptosis3.21e-021.00e+004.9401547
GO:0003743translation initiation factor activity3.35e-021.00e+004.8791849
GO:0035690cellular response to drug3.35e-021.00e+004.8791249
GO:0045216cell-cell junction organization3.68e-021.00e+004.7391254
GO:0000932cytoplasmic mRNA processing body3.68e-021.00e+004.7391354
GO:0006968cellular defense response3.68e-021.00e+004.7391154
GO:0097193intrinsic apoptotic signaling pathway3.75e-021.00e+004.7131655
GO:0007202activation of phospholipase C activity3.75e-021.00e+004.7131355
GO:0002039p53 binding3.75e-021.00e+004.7131755
GO:0000724double-strand break repair via homologous recombination3.75e-021.00e+004.7131355
GO:0007596blood coagulation3.78e-021.00e+002.664218455
GO:0008104protein localization3.82e-021.00e+004.6871356
GO:0000723telomere maintenance3.82e-021.00e+004.6871656
GO:0005643nuclear pore3.88e-021.00e+004.6611457
GO:0051087chaperone binding4.02e-021.00e+004.6121659
GO:0044267cellular protein metabolic process4.07e-021.00e+002.605229474
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway4.15e-021.00e+004.5631261
GO:0042802identical protein binding4.23e-021.00e+002.575220484
GO:0044281small molecule metabolic process4.53e-021.00e+001.8373581211
GO:0035264multicellular organism growth4.55e-021.00e+004.4281167
GO:0003697single-stranded DNA binding4.62e-021.00e+004.4071568
GO:0034329cell junction assembly4.62e-021.00e+004.4071168
GO:0042826histone deacetylase binding4.88e-021.00e+004.3241272
GO:0000785chromatin4.95e-021.00e+004.3041473
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis5.02e-021.00e+004.2851674
GO:0002020protease binding5.02e-021.00e+004.2851474
GO:0008584male gonad development5.08e-021.00e+004.2651375
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation5.08e-021.00e+004.2651375
GO:0007265Ras protein signal transduction5.08e-021.00e+004.2651275
GO:0071013catalytic step 2 spliceosome5.28e-021.00e+004.2091478
GO:0005524ATP binding5.40e-021.00e+001.7373601298
GO:0005681spliceosomal complex5.61e-021.00e+004.1191483
GO:0050852T cell receptor signaling pathway5.74e-021.00e+004.0851485
GO:0016363nuclear matrix6.14e-021.00e+003.98611291
GO:0006928cellular component movement6.14e-021.00e+003.9861791
GO:0005200structural constituent of cytoskeleton6.14e-021.00e+003.9861891
GO:0045087innate immune response6.16e-021.00e+002.275224596
GO:0001649osteoblast differentiation6.20e-021.00e+003.9711692
GO:0071456cellular response to hypoxia6.20e-021.00e+003.9711692
GO:0014069postsynaptic density7.05e-021.00e+003.78013105
GO:0030308negative regulation of cell growth7.37e-021.00e+003.71316110
GO:0006461protein complex assembly7.44e-021.00e+003.70016111
GO:0072562blood microparticle7.44e-021.00e+003.70013111
GO:0030529ribonucleoprotein complex7.50e-021.00e+003.68718112
GO:0005635nuclear envelope7.57e-021.00e+003.67416113
GO:0019058viral life cycle7.70e-021.00e+003.649113115
GO:0006325chromatin organization7.89e-021.00e+003.61215118
GO:0007219Notch signaling pathway8.02e-021.00e+003.58715120
GO:0006260DNA replication8.08e-021.00e+003.57519121
GO:0007050cell cycle arrest8.27e-021.00e+003.54019124
GO:0009615response to virus8.40e-021.00e+003.51715126
GO:0006511ubiquitin-dependent protein catabolic process8.40e-021.00e+003.51715126
GO:0007179transforming growth factor beta receptor signaling pathway8.53e-021.00e+003.49414128
GO:0006413translational initiation8.72e-021.00e+003.461117131
GO:0018108peptidyl-tyrosine phosphorylation8.79e-021.00e+003.45017132
GO:0005911cell-cell junction9.04e-021.00e+003.40714136
GO:0006457protein folding9.49e-021.00e+003.33417143
GO:0061024membrane organization9.61e-021.00e+003.31417145
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription9.74e-021.00e+003.29413147
GO:0006974cellular response to DNA damage stimulus9.99e-021.00e+003.25618151
GO:0000398mRNA splicing, via spliceosome1.08e-011.00e+003.13718164
GO:0030424axon1.09e-011.00e+003.11914166
GO:0038095Fc-epsilon receptor signaling pathway1.11e-011.00e+003.102112168
GO:0031965nuclear membrane1.11e-011.00e+003.10213168
GO:0044212transcription regulatory region DNA binding1.11e-011.00e+003.10216168
GO:0019904protein domain specific binding1.17e-011.00e+003.01016179
GO:0005759mitochondrial matrix1.47e-011.00e+002.661114228
GO:0008380RNA splicing1.47e-011.00e+002.661111228
GO:0008270zinc ion binding1.49e-011.00e+001.533212997
GO:0006412translation1.49e-011.00e+002.649120230
GO:0008134transcription factor binding1.56e-011.00e+002.57518242
GO:0000166nucleotide binding1.66e-011.00e+002.47715259
GO:0006281DNA repair1.67e-011.00e+002.466118261
GO:0043065positive regulation of apoptotic process1.71e-011.00e+002.428110268
GO:0005856cytoskeleton1.84e-011.00e+002.309112291
GO:0030154cell differentiation1.90e-011.00e+002.26115301
GO:0035556intracellular signal transduction1.91e-011.00e+002.25119303
GO:0007275multicellular organismal development1.99e-011.00e+002.19015316
GO:0007411axon guidance2.00e-011.00e+002.177113319
GO:0003682chromatin binding2.05e-011.00e+002.141111327
GO:0008283cell proliferation2.06e-011.00e+002.137114328
GO:0008285negative regulation of cell proliferation2.20e-011.00e+002.031111353
GO:0005925focal adhesion2.27e-011.00e+001.978119366
GO:0046872metal ion binding2.28e-011.00e+001.1422251307
GO:0046982protein heterodimerization activity2.34e-011.00e+001.924113380
GO:0005737cytoplasm2.51e-011.00e+000.61541103767
GO:0045892negative regulation of transcription, DNA-templated2.52e-011.00e+001.804115413
GO:0045893positive regulation of transcription, DNA-templated2.86e-011.00e+001.593113478
GO:0005783endoplasmic reticulum3.25e-011.00e+001.375110556
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.32e-011.00e+001.339116570
GO:0003700sequence-specific DNA binding transcription factor activity3.92e-011.00e+001.045111699
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.30e-011.00e+000.870119789
GO:0007165signal transduction4.78e-011.00e+000.669124907
GO:0005615extracellular space4.97e-011.00e+000.592117957
GO:0006355regulation of transcription, DNA-templated5.12e-011.00e+000.533118997
GO:0005739mitochondrion5.12e-011.00e+000.531128998
GO:0003677DNA binding5.86e-011.00e+000.2441281218