Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 1.002 | 3.25e-18 | 5.25e-04 | 1.26e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
CDC16 | 8881 | 25 | 0.950 | 1.020 | 80 | Yes | - |
EIF2S2 | 8894 | 27 | 1.075 | 1.138 | 81 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
[ PFN1 ] | 5216 | 1 | -0.143 | 1.002 | 78 | - | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
CLTC | 1213 | PFN1 | 5216 | pp | -- | int.I2D: BioGrid_Mouse |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PFN1 | 5216 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Mouse, HPRD, MINT_Mouse, BCI, IntAct; int.HPRD: in vitro; int.DIP: MI:0407(direct interaction) |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
CLTC | 1213 | EIF2S2 | 8894 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CDC16 | 8881 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.23e-09 | 1.77e-05 | 6.531 | 5 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.80e-09 | 2.59e-05 | 6.424 | 5 | 22 | 70 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.39e-09 | 3.44e-05 | 6.344 | 5 | 22 | 74 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.33e-09 | 4.81e-05 | 6.249 | 5 | 23 | 79 |
GO:0005829 | cytosol | 4.14e-08 | 5.97e-04 | 2.405 | 11 | 132 | 2496 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.20e-08 | 8.94e-04 | 6.587 | 4 | 17 | 50 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.22e-08 | 1.19e-03 | 5.334 | 5 | 32 | 149 |
GO:0000502 | proteasome complex | 1.14e-07 | 1.64e-03 | 6.373 | 4 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.70e-07 | 2.45e-03 | 6.231 | 4 | 19 | 64 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 2.74e-07 | 3.95e-03 | 6.061 | 4 | 20 | 72 |
GO:0000278 | mitotic cell cycle | 3.07e-07 | 4.44e-03 | 4.205 | 6 | 48 | 391 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 3.23e-07 | 4.67e-03 | 6.002 | 4 | 20 | 75 |
GO:0005654 | nucleoplasm | 3.69e-07 | 5.32e-03 | 3.152 | 8 | 76 | 1082 |
GO:0016071 | mRNA metabolic process | 6.13e-07 | 8.84e-03 | 4.752 | 5 | 31 | 223 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 7.38e-07 | 1.06e-02 | 5.708 | 4 | 21 | 92 |
GO:0016070 | RNA metabolic process | 1.02e-06 | 1.46e-02 | 4.605 | 5 | 32 | 247 |
GO:0000209 | protein polyubiquitination | 1.87e-06 | 2.70e-02 | 5.373 | 4 | 20 | 116 |
GO:0016032 | viral process | 1.91e-06 | 2.76e-02 | 3.755 | 6 | 55 | 534 |
GO:0042981 | regulation of apoptotic process | 5.21e-06 | 7.52e-02 | 5.002 | 4 | 24 | 150 |
GO:0010467 | gene expression | 7.08e-06 | 1.02e-01 | 3.430 | 6 | 59 | 669 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.77e-06 | 1.26e-01 | 4.813 | 4 | 20 | 171 |
GO:0005838 | proteasome regulatory particle | 4.17e-05 | 6.01e-01 | 7.646 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 8.57e-05 | 1.00e+00 | 7.144 | 2 | 8 | 17 |
GO:0005839 | proteasome core complex | 9.64e-05 | 1.00e+00 | 7.061 | 2 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.08e-04 | 1.00e+00 | 6.983 | 2 | 8 | 19 |
GO:0070062 | extracellular vesicular exosome | 1.53e-04 | 1.00e+00 | 2.002 | 8 | 104 | 2400 |
GO:0043066 | negative regulation of apoptotic process | 3.02e-04 | 1.00e+00 | 3.503 | 4 | 31 | 424 |
GO:0005515 | protein binding | 4.97e-04 | 1.00e+00 | 1.134 | 11 | 184 | 6024 |
GO:0006915 | apoptotic process | 8.39e-04 | 1.00e+00 | 3.115 | 4 | 33 | 555 |
GO:0016020 | membrane | 1.23e-03 | 1.00e+00 | 2.101 | 6 | 90 | 1681 |
GO:0051054 | positive regulation of DNA metabolic process | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0002176 | male germ cell proliferation | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 3 |
GO:0071439 | clathrin complex | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 3 |
GO:0005925 | focal adhesion | 3.01e-03 | 1.00e+00 | 3.300 | 3 | 19 | 366 |
GO:0000774 | adenyl-nucleotide exchange factor activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0032232 | negative regulation of actin filament bundle assembly | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0072562 | blood microparticle | 3.68e-03 | 1.00e+00 | 4.437 | 2 | 3 | 111 |
GO:0005819 | spindle | 3.75e-03 | 1.00e+00 | 4.424 | 2 | 7 | 112 |
GO:1900029 | positive regulation of ruffle assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0030957 | Tat protein binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0030118 | clathrin coat | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0006413 | translational initiation | 5.09e-03 | 1.00e+00 | 4.198 | 2 | 17 | 131 |
GO:0030132 | clathrin coat of coated pit | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 |
GO:0000028 | ribosomal small subunit assembly | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 |
GO:0061024 | membrane organization | 6.20e-03 | 1.00e+00 | 4.051 | 2 | 7 | 145 |
GO:0044267 | cellular protein metabolic process | 6.22e-03 | 1.00e+00 | 2.927 | 3 | 29 | 474 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 4 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0030837 | negative regulation of actin filament polymerization | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0051497 | negative regulation of stress fiber assembly | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0044822 | poly(A) RNA binding | 8.79e-03 | 1.00e+00 | 2.187 | 4 | 49 | 1056 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 4 | 11 |
GO:0031625 | ubiquitin protein ligase binding | 9.22e-03 | 1.00e+00 | 3.755 | 2 | 14 | 178 |
GO:0005662 | DNA replication factor A complex | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 4 | 14 |
GO:0050998 | nitric-oxide synthase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 16 |
GO:0044281 | small molecule metabolic process | 1.42e-02 | 1.00e+00 | 1.989 | 4 | 58 | 1211 |
GO:0007067 | mitotic nuclear division | 1.47e-02 | 1.00e+00 | 3.405 | 2 | 14 | 227 |
GO:0007088 | regulation of mitosis | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0070064 | proline-rich region binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 2 | 18 |
GO:0035861 | site of double-strand break | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0006412 | translation | 1.50e-02 | 1.00e+00 | 3.386 | 2 | 20 | 230 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0005680 | anaphase-promoting complex | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 4 | 20 |
GO:0006298 | mismatch repair | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 5 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0005844 | polysome | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006281 | DNA repair | 1.91e-02 | 1.00e+00 | 3.203 | 2 | 18 | 261 |
GO:0008135 | translation factor activity, nucleic acid binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 7 | 24 |
GO:0032781 | positive regulation of ATPase activity | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 24 |
GO:0010634 | positive regulation of epithelial cell migration | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 24 |
GO:0000722 | telomere maintenance via recombination | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 5 | 25 |
GO:0070979 | protein K11-linked ubiquitination | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 6 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 26 |
GO:0043022 | ribosome binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 27 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 28 |
GO:0005856 | cytoskeleton | 2.34e-02 | 1.00e+00 | 3.046 | 2 | 12 | 291 |
GO:0019005 | SCF ubiquitin ligase complex | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 |
GO:0043234 | protein complex | 2.40e-02 | 1.00e+00 | 3.027 | 2 | 18 | 295 |
GO:0033572 | transferrin transport | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 5 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 7 | 30 |
GO:0017048 | Rho GTPase binding | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 1 | 31 |
GO:0031623 | receptor internalization | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 2 | 31 |
GO:0007094 | mitotic spindle assembly checkpoint | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 4 | 31 |
GO:0019901 | protein kinase binding | 2.75e-02 | 1.00e+00 | 2.923 | 2 | 21 | 317 |
GO:0032588 | trans-Golgi network membrane | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 |
GO:0030838 | positive regulation of actin filament polymerization | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0005876 | spindle microtubule | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0005813 | centrosome | 2.89e-02 | 1.00e+00 | 2.882 | 2 | 14 | 326 |
GO:0034332 | adherens junction organization | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 3 | 37 |
GO:0051496 | positive regulation of stress fiber assembly | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0070527 | platelet aggregation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0003723 | RNA binding | 3.16e-02 | 1.00e+00 | 2.813 | 2 | 20 | 342 |
GO:0022627 | cytosolic small ribosomal subunit | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 39 |
GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 2 | 39 |
GO:0030136 | clathrin-coated vesicle | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 4 | 42 |
GO:0071363 | cellular response to growth factor stimulus | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 42 |
GO:0006892 | post-Golgi vesicle-mediated transport | 3.52e-02 | 1.00e+00 | 4.805 | 1 | 3 | 43 |
GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 |
GO:0050434 | positive regulation of viral transcription | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 6 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 7 | 46 |
GO:0005730 | nucleolus | 3.91e-02 | 1.00e+00 | 1.551 | 4 | 69 | 1641 |
GO:0003743 | translation initiation factor activity | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 8 | 49 |
GO:0003684 | damaged DNA binding | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 7 | 49 |
GO:0003725 | double-stranded RNA binding | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 54 |
GO:0000724 | double-strand break repair via homologous recombination | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 6 | 56 |
GO:0019903 | protein phosphatase binding | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0005634 | nucleus | 5.06e-02 | 1.00e+00 | 0.884 | 7 | 136 | 4559 |
GO:0007596 | blood coagulation | 5.32e-02 | 1.00e+00 | 2.401 | 2 | 18 | 455 |
GO:0006289 | nucleotide-excision repair | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 5 | 68 |
GO:0001843 | neural tube closure | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 4 | 74 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 6 | 74 |
GO:0008584 | male gonad development | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 3 | 75 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 2 | 75 |
GO:0019083 | viral transcription | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 10 | 81 |
GO:0002576 | platelet degranulation | 6.62e-02 | 1.00e+00 | 3.874 | 1 | 4 | 82 |
GO:0006898 | receptor-mediated endocytosis | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 3 | 84 |
GO:0047485 | protein N-terminus binding | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 5 | 86 |
GO:0006415 | translational termination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 10 | 87 |
GO:0016605 | PML body | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 3 | 88 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 7 | 90 |
GO:0042470 | melanosome | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 4 | 110 |
GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 8 | 112 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.09e-02 | 1.00e+00 | 3.398 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 13 | 115 |
GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 9.62e-02 | 1.00e+00 | 3.312 | 1 | 9 | 121 |
GO:0030036 | actin cytoskeleton organization | 9.77e-02 | 1.00e+00 | 3.289 | 1 | 5 | 123 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 9 | 129 |
GO:0031982 | vesicle | 1.04e-01 | 1.00e+00 | 3.198 | 1 | 9 | 131 |
GO:0003735 | structural constituent of ribosome | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 10 | 137 |
GO:0045202 | synapse | 1.08e-01 | 1.00e+00 | 3.144 | 1 | 3 | 136 |
GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 |
GO:0005198 | structural molecule activity | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 150 |
GO:0043005 | neuron projection | 1.23e-01 | 1.00e+00 | 2.937 | 1 | 6 | 157 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 7 | 165 |
GO:0030424 | axon | 1.30e-01 | 1.00e+00 | 2.856 | 1 | 4 | 166 |
GO:0006886 | intracellular protein transport | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 5 | 171 |
GO:0032403 | protein complex binding | 1.42e-01 | 1.00e+00 | 2.715 | 1 | 10 | 183 |
GO:0001701 | in utero embryonic development | 1.55e-01 | 1.00e+00 | 2.580 | 1 | 8 | 201 |
GO:0030168 | platelet activation | 1.58e-01 | 1.00e+00 | 2.552 | 1 | 10 | 205 |
GO:0004842 | ubiquitin-protein transferase activity | 1.93e-01 | 1.00e+00 | 2.237 | 1 | 6 | 255 |
GO:0005102 | receptor binding | 1.96e-01 | 1.00e+00 | 2.209 | 1 | 6 | 260 |
GO:0003779 | actin binding | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 12 | 266 |
GO:0019899 | enzyme binding | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 12 | 277 |
GO:0016567 | protein ubiquitination | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 5 | 295 |
GO:0007411 | axon guidance | 2.35e-01 | 1.00e+00 | 1.914 | 1 | 13 | 319 |
GO:0008283 | cell proliferation | 2.41e-01 | 1.00e+00 | 1.874 | 1 | 14 | 328 |
GO:0007155 | cell adhesion | 2.67e-01 | 1.00e+00 | 1.704 | 1 | 6 | 369 |
GO:0005737 | cytoplasm | 3.86e-01 | 1.00e+00 | 0.352 | 4 | 110 | 3767 |
GO:0045087 | innate immune response | 3.97e-01 | 1.00e+00 | 1.012 | 1 | 24 | 596 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4.91e-01 | 1.00e+00 | 0.607 | 1 | 19 | 789 |
GO:0005615 | extracellular space | 5.61e-01 | 1.00e+00 | 0.329 | 1 | 17 | 957 |
GO:0008270 | zinc ion binding | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 12 | 997 |
GO:0005886 | plasma membrane | 6.61e-01 | 1.00e+00 | -0.103 | 2 | 45 | 2582 |
GO:0005524 | ATP binding | 6.78e-01 | 1.00e+00 | -0.111 | 1 | 60 | 1298 |
GO:0046872 | metal ion binding | 6.80e-01 | 1.00e+00 | -0.121 | 1 | 25 | 1307 |