Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.946 | 6.14e-16 | 1.95e-03 | 3.37e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMA3 | 5684 | 12 | 0.533 | 1.026 | 218 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMC3 | 5702 | 9 | 0.719 | 1.002 | 255 | Yes | - |
HNRNPC | 3183 | 20 | 1.812 | 1.026 | 119 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
[ ASS1 ] | 445 | 1 | -0.137 | 0.946 | 49 | - | - |
DLST | 1743 | 5 | 0.646 | 1.026 | 135 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
RPL11 | 6135 | 9 | 0.718 | 1.017 | 200 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
RPL14 | 9045 | 42 | 1.250 | 1.113 | 143 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
RUVBL2 | 10856 | 5 | 0.693 | 1.003 | 345 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA2 | 5683 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD3 | 5709 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
ASS1 | 445 | PSMA3 | 5684 | pp | -- | int.I2D: YeastLow |
ASS1 | 445 | RPL11 | 6135 | pp | -- | int.I2D: IntAct_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMC3 | 5702 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD11 | 5717 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd; int.HPRD: in vitro |
DLST | 1743 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
DLST | 1743 | PSMA3 | 5684 | pp | -- | int.I2D: YeastLow |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMC3 | 5702 | RPL11 | 6135 | pp | -- | int.I2D: BioGrid_Yeast |
PSMC3 | 5702 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
RPSA | 3921 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA3 | 5684 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ASS1 | 445 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
DLST | 1743 | RPL11 | 6135 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid |
ASS1 | 445 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
PSMC3 | 5702 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh |
PSMA1 | 5682 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
DLST | 1743 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
RPL11 | 6135 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
PSMA3 | 5684 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast, BioGrid, YeastLow |
RPL11 | 6135 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMC3 | 5702 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
PSMC3 | 5702 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh |
ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
RPS11 | 6205 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid |
RPSA | 3921 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMA3 | 5684 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
DLST | 1743 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
ASS1 | 445 | DLST | 1743 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RPL11 | 6135 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016071 | mRNA metabolic process | 3.85e-17 | 5.55e-13 | 5.475 | 11 | 31 | 223 |
GO:0016070 | RNA metabolic process | 1.21e-16 | 1.74e-12 | 5.327 | 11 | 32 | 247 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.99e-14 | 5.76e-10 | 5.568 | 9 | 20 | 171 |
GO:0006521 | regulation of cellular amino acid metabolic process | 4.34e-14 | 6.26e-10 | 6.980 | 7 | 17 | 50 |
GO:0000502 | proteasome complex | 1.30e-13 | 1.88e-09 | 6.765 | 7 | 17 | 58 |
GO:0010467 | gene expression | 1.38e-13 | 1.99e-09 | 4.015 | 12 | 59 | 669 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.68e-13 | 3.86e-09 | 6.623 | 7 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.00e-13 | 4.33e-09 | 6.601 | 7 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.15e-13 | 7.43e-09 | 6.494 | 7 | 22 | 70 |
GO:0016032 | viral process | 5.98e-13 | 8.63e-09 | 4.215 | 11 | 55 | 534 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 6.32e-13 | 9.12e-09 | 6.454 | 7 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.72e-13 | 1.11e-08 | 6.414 | 7 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.50e-13 | 1.23e-08 | 6.395 | 7 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.24e-12 | 1.79e-08 | 6.320 | 7 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 3.72e-12 | 5.36e-08 | 6.100 | 7 | 21 | 92 |
GO:0000209 | protein polyubiquitination | 1.95e-11 | 2.82e-07 | 5.765 | 7 | 20 | 116 |
GO:0070062 | extracellular vesicular exosome | 2.71e-11 | 3.90e-07 | 2.494 | 15 | 104 | 2400 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.15e-10 | 1.66e-06 | 5.404 | 7 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 1.21e-10 | 1.74e-06 | 5.395 | 7 | 24 | 150 |
GO:0005829 | cytosol | 1.77e-09 | 2.56e-05 | 2.338 | 14 | 132 | 2496 |
GO:0005839 | proteasome core complex | 3.06e-09 | 4.42e-05 | 7.646 | 4 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 3.88e-09 | 5.59e-05 | 7.568 | 4 | 8 | 19 |
GO:0005654 | nucleoplasm | 2.86e-08 | 4.12e-04 | 3.059 | 10 | 76 | 1082 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.25e-08 | 9.02e-04 | 8.401 | 3 | 4 | 8 |
GO:0000278 | mitotic cell cycle | 9.45e-08 | 1.36e-03 | 4.012 | 7 | 48 | 391 |
GO:0016020 | membrane | 1.31e-07 | 1.88e-03 | 2.560 | 11 | 90 | 1681 |
GO:0043066 | negative regulation of apoptotic process | 1.64e-07 | 2.37e-03 | 3.896 | 7 | 31 | 424 |
GO:0022624 | proteasome accessory complex | 7.54e-07 | 1.09e-02 | 7.314 | 3 | 8 | 17 |
GO:0006915 | apoptotic process | 1.02e-06 | 1.47e-02 | 3.507 | 7 | 33 | 555 |
GO:0044281 | small molecule metabolic process | 1.34e-06 | 1.93e-02 | 2.744 | 9 | 58 | 1211 |
GO:0019083 | viral transcription | 1.60e-06 | 2.30e-02 | 5.476 | 4 | 10 | 81 |
GO:0006415 | translational termination | 2.13e-06 | 3.07e-02 | 5.373 | 4 | 10 | 87 |
GO:0006414 | translational elongation | 2.78e-06 | 4.01e-02 | 5.277 | 4 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 4.34e-06 | 6.26e-02 | 5.116 | 4 | 10 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 6.26e-06 | 9.03e-02 | 4.983 | 4 | 11 | 114 |
GO:0019058 | viral life cycle | 6.48e-06 | 9.35e-02 | 4.971 | 4 | 13 | 115 |
GO:0006413 | translational initiation | 1.09e-05 | 1.57e-01 | 4.783 | 4 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 1.30e-05 | 1.87e-01 | 4.718 | 4 | 10 | 137 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 2.54e-05 | 3.66e-01 | 5.673 | 3 | 5 | 53 |
GO:0005838 | proteasome regulatory particle | 7.57e-05 | 1.00e+00 | 7.231 | 2 | 7 | 12 |
GO:0042273 | ribosomal large subunit biogenesis | 8.94e-05 | 1.00e+00 | 7.116 | 2 | 4 | 13 |
GO:0006412 | translation | 9.86e-05 | 1.00e+00 | 3.971 | 4 | 20 | 230 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.04e-04 | 1.00e+00 | 7.009 | 2 | 4 | 14 |
GO:0044267 | cellular protein metabolic process | 1.21e-04 | 1.00e+00 | 3.249 | 5 | 29 | 474 |
GO:0005515 | protein binding | 2.18e-04 | 1.00e+00 | 1.067 | 14 | 184 | 6024 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 4 | 23 |
GO:0019843 | rRNA binding | 3.98e-04 | 1.00e+00 | 6.061 | 2 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 3.98e-04 | 1.00e+00 | 6.061 | 2 | 4 | 27 |
GO:0003723 | RNA binding | 4.51e-04 | 1.00e+00 | 3.398 | 4 | 20 | 342 |
GO:0005634 | nucleus | 4.55e-04 | 1.00e+00 | 1.247 | 12 | 136 | 4559 |
GO:0044822 | poly(A) RNA binding | 6.42e-04 | 1.00e+00 | 2.357 | 6 | 49 | 1056 |
GO:0022627 | cytosolic small ribosomal subunit | 8.35e-04 | 1.00e+00 | 5.531 | 2 | 4 | 39 |
GO:1903038 | negative regulation of leukocyte cell-cell adhesion | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0004149 | dihydrolipoyllysine-residue succinyltransferase activity | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0004055 | argininosuccinate synthase activity | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0000053 | argininosuccinate metabolic process | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0022625 | cytosolic large ribosomal subunit | 1.32e-03 | 1.00e+00 | 5.201 | 2 | 6 | 49 |
GO:0000932 | cytoplasmic mRNA processing body | 1.60e-03 | 1.00e+00 | 5.061 | 2 | 3 | 54 |
GO:0071418 | cellular response to amine stimulus | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0071242 | cellular response to ammonium ion | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0010046 | response to mycotoxin | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0045252 | oxoglutarate dehydrogenase complex | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 2 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0071400 | cellular response to oleic acid | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0071733 | transcriptional activation by promoter-enhancer looping | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0033512 | L-lysine catabolic process to acetyl-CoA via saccharopine | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0006526 | arginine biosynthetic process | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0071899 | negative regulation of estrogen receptor binding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0043141 | ATP-dependent 5'-3' DNA helicase activity | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0000052 | citrulline metabolic process | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0001649 | osteoblast differentiation | 4.56e-03 | 1.00e+00 | 4.293 | 2 | 6 | 92 |
GO:0006364 | rRNA processing | 4.75e-03 | 1.00e+00 | 4.261 | 2 | 6 | 94 |
GO:0071169 | establishment of protein localization to chromatin | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0070852 | cell body fiber | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0005730 | nucleolus | 6.27e-03 | 1.00e+00 | 1.721 | 6 | 69 | 1641 |
GO:0030957 | Tat protein binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0006531 | aspartate metabolic process | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0030529 | ribonucleoprotein complex | 6.68e-03 | 1.00e+00 | 4.009 | 2 | 8 | 112 |
GO:0006325 | chromatin organization | 7.39e-03 | 1.00e+00 | 3.933 | 2 | 5 | 118 |
GO:0000028 | ribosomal small subunit assembly | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0060539 | diaphragm development | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0071499 | cellular response to laminar fluid shear stress | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0060416 | response to growth hormone | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0000790 | nuclear chromatin | 8.78e-03 | 1.00e+00 | 3.805 | 2 | 9 | 129 |
GO:0007494 | midgut development | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0006554 | lysine catabolic process | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 2 | 8 |
GO:0000812 | Swr1 complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 3 | 8 |
GO:0000050 | urea cycle | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0015643 | toxic substance binding | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0016887 | ATPase activity | 1.03e-02 | 1.00e+00 | 3.687 | 2 | 7 | 140 |
GO:0006457 | protein folding | 1.07e-02 | 1.00e+00 | 3.656 | 2 | 7 | 143 |
GO:0045120 | pronucleus | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 2 | 11 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 12 |
GO:0043968 | histone H2A acetylation | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 12 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.41e-02 | 1.00e+00 | 3.450 | 2 | 7 | 165 |
GO:0030234 | enzyme regulator activity | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0008266 | poly(U) RNA binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 13 |
GO:0031011 | Ino80 complex | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 3 | 14 |
GO:0035066 | positive regulation of histone acetylation | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 3 | 16 |
GO:0003678 | DNA helicase activity | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:1903506 | regulation of nucleic acid-templated transcription | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0071392 | cellular response to estradiol stimulus | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0048863 | stem cell differentiation | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0005719 | nuclear euchromatin | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 2 | 19 |
GO:0016597 | amino acid binding | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 1 | 20 |
GO:0030863 | cortical cytoskeleton | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 4 | 22 |
GO:0005844 | polysome | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 4 | 23 |
GO:0043236 | laminin binding | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0071346 | cellular response to interferon-gamma | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0010043 | response to zinc ion | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 1 | 24 |
GO:0003730 | mRNA 3'-UTR binding | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 2 | 26 |
GO:0004003 | ATP-dependent DNA helicase activity | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 2 | 27 |
GO:0043022 | ribosome binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0071339 | MLL1 complex | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0043967 | histone H4 acetylation | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0006099 | tricarboxylic acid cycle | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 28 |
GO:0034504 | protein localization to nucleus | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 2 | 28 |
GO:0034644 | cellular response to UV | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 5 | 30 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 2 | 32 |
GO:0001895 | retina homeostasis | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 1 | 34 |
GO:0006953 | acute-phase response | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 2 | 35 |
GO:0006605 | protein targeting | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 2 | 35 |
GO:0045429 | positive regulation of nitric oxide biosynthetic process | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 3 | 35 |
GO:0071377 | cellular response to glucagon stimulus | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 2 | 35 |
GO:0034332 | adherens junction organization | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.03e-02 | 1.00e+00 | 4.607 | 1 | 4 | 37 |
GO:0006200 | ATP catabolic process | 4.07e-02 | 1.00e+00 | 2.626 | 2 | 15 | 292 |
GO:0043234 | protein complex | 4.14e-02 | 1.00e+00 | 2.612 | 2 | 18 | 295 |
GO:0070527 | platelet aggregation | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0031490 | chromatin DNA binding | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 3 | 38 |
GO:0071320 | cellular response to cAMP | 4.35e-02 | 1.00e+00 | 4.494 | 1 | 1 | 40 |
GO:0032508 | DNA duplex unwinding | 4.45e-02 | 1.00e+00 | 4.459 | 1 | 3 | 41 |
GO:0071230 | cellular response to amino acid stimulus | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 3 | 42 |
GO:0021762 | substantia nigra development | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 2 | 44 |
GO:0005524 | ATP binding | 4.95e-02 | 1.00e+00 | 1.474 | 4 | 60 | 1298 |
GO:0003684 | damaged DNA binding | 5.30e-02 | 1.00e+00 | 4.201 | 1 | 7 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 3 | 50 |
GO:0040008 | regulation of growth | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 5 | 50 |
GO:0045216 | cell-cell junction organization | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 2 | 54 |
GO:0043204 | perikaryon | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 1 | 55 |
GO:0005925 | focal adhesion | 6.10e-02 | 1.00e+00 | 2.300 | 2 | 19 | 366 |
GO:0071356 | cellular response to tumor necrosis factor | 6.14e-02 | 1.00e+00 | 3.983 | 1 | 1 | 57 |
GO:0005840 | ribosome | 6.25e-02 | 1.00e+00 | 3.958 | 1 | 1 | 58 |
GO:0006310 | DNA recombination | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 2 | 65 |
GO:0006338 | chromatin remodeling | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 5 | 66 |
GO:0034329 | cell junction assembly | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 1 | 68 |
GO:0032355 | response to estradiol | 7.60e-02 | 1.00e+00 | 3.666 | 1 | 5 | 71 |
GO:0007584 | response to nutrient | 7.60e-02 | 1.00e+00 | 3.666 | 1 | 4 | 71 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.90e-02 | 1.00e+00 | 3.607 | 1 | 6 | 74 |
GO:0001889 | liver development | 8.21e-02 | 1.00e+00 | 3.549 | 1 | 4 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 8.31e-02 | 1.00e+00 | 3.531 | 1 | 4 | 78 |
GO:0001822 | kidney development | 8.31e-02 | 1.00e+00 | 3.531 | 1 | 2 | 78 |
GO:0071222 | cellular response to lipopolysaccharide | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 1 | 81 |
GO:0005681 | spliceosomal complex | 8.82e-02 | 1.00e+00 | 3.441 | 1 | 4 | 83 |
GO:0016363 | nuclear matrix | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 12 | 91 |
GO:0006928 | cellular component movement | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 8 | 91 |
GO:0005737 | cytoplasm | 9.70e-02 | 1.00e+00 | 0.744 | 7 | 110 | 3767 |
GO:0051082 | unfolded protein binding | 9.84e-02 | 1.00e+00 | 3.277 | 1 | 5 | 93 |
GO:0042802 | identical protein binding | 9.90e-02 | 1.00e+00 | 1.897 | 2 | 20 | 484 |
GO:0014069 | postsynaptic density | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 3 | 105 |
GO:0005741 | mitochondrial outer membrane | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 7 | 105 |
GO:0015630 | microtubule cytoskeleton | 1.15e-01 | 1.00e+00 | 3.035 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 1.16e-01 | 1.00e+00 | 3.022 | 1 | 3 | 111 |
GO:0044237 | cellular metabolic process | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 5 | 117 |
GO:0007568 | aging | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 3 | 117 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0061024 | membrane organization | 1.49e-01 | 1.00e+00 | 2.636 | 1 | 7 | 145 |
GO:0000398 | mRNA splicing, via spliceosome | 1.67e-01 | 1.00e+00 | 2.459 | 1 | 8 | 164 |
GO:0030424 | axon | 1.69e-01 | 1.00e+00 | 2.441 | 1 | 4 | 166 |
GO:0005764 | lysosome | 1.75e-01 | 1.00e+00 | 2.390 | 1 | 2 | 172 |
GO:0003714 | transcription corepressor activity | 1.80e-01 | 1.00e+00 | 2.340 | 1 | 8 | 178 |
GO:0005622 | intracellular | 2.07e-01 | 1.00e+00 | 2.123 | 1 | 6 | 207 |
GO:0008380 | RNA splicing | 2.25e-01 | 1.00e+00 | 1.983 | 1 | 11 | 228 |
GO:0005759 | mitochondrial matrix | 2.25e-01 | 1.00e+00 | 1.983 | 1 | 14 | 228 |
GO:0003713 | transcription coactivator activity | 2.33e-01 | 1.00e+00 | 1.927 | 1 | 10 | 237 |
GO:0000166 | nucleotide binding | 2.52e-01 | 1.00e+00 | 1.799 | 1 | 5 | 259 |
GO:0006281 | DNA repair | 2.53e-01 | 1.00e+00 | 1.788 | 1 | 18 | 261 |
GO:0042493 | response to drug | 2.73e-01 | 1.00e+00 | 1.666 | 1 | 13 | 284 |
GO:0005856 | cytoskeleton | 2.78e-01 | 1.00e+00 | 1.631 | 1 | 12 | 291 |
GO:0019901 | protein kinase binding | 2.99e-01 | 1.00e+00 | 1.508 | 1 | 21 | 317 |
GO:0007411 | axon guidance | 3.01e-01 | 1.00e+00 | 1.499 | 1 | 13 | 319 |
GO:0005813 | centrosome | 3.06e-01 | 1.00e+00 | 1.467 | 1 | 14 | 326 |
GO:0007155 | cell adhesion | 3.40e-01 | 1.00e+00 | 1.289 | 1 | 6 | 369 |
GO:0007596 | blood coagulation | 4.01e-01 | 1.00e+00 | 0.986 | 1 | 18 | 455 |
GO:0005783 | endoplasmic reticulum | 4.67e-01 | 1.00e+00 | 0.697 | 1 | 10 | 556 |
GO:0045087 | innate immune response | 4.91e-01 | 1.00e+00 | 0.597 | 1 | 24 | 596 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 5.94e-01 | 1.00e+00 | 0.192 | 1 | 19 | 789 |
GO:0005615 | extracellular space | 6.67e-01 | 1.00e+00 | -0.086 | 1 | 17 | 957 |
GO:0006351 | transcription, DNA-templated | 8.16e-01 | 1.00e+00 | -0.682 | 1 | 31 | 1446 |
GO:0005886 | plasma membrane | 9.57e-01 | 1.00e+00 | -1.518 | 1 | 45 | 2582 |