TP53

Genes (1)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
TP53 7157 230.4320.833665TF--

Gene info in the NCBI database: TP53

23 meta-subnetworks

Subnetwork ID Size Highlighted genes
meta-reg-snw-55660 25 68
meta-int-snw-1457 2 6
meta-reg-snw-317781 53 94
meta-reg-snw-5905 11 45
meta-reg-snw-4522 49 93
meta-int-snw-9527 3 12
meta-int-snw-445 17 44
meta-int-snw-10209 7 29
meta-reg-snw-9134 5 39
meta-reg-snw-324 2 6
meta-int-snw-5743 11 35
meta-int-snw-2617 3 20
meta-reg-snw-56655 63 99
meta-reg-snw-5686 35 80
meta-reg-snw-10213 44 87
meta-reg-snw-1434 41 87
meta-reg-snw-2237 10 50
meta-reg-snw-4800 7 44
meta-reg-snw-11277 51 90
meta-reg-snw-1478 10 53
meta-int-snw-3838 5 19
meta-int-snw-7167 2 18
meta-reg-snw-5887 7 33

Related GO terms (137)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005515protein binding1726127
GO:0045892negative regulation of transcription, DNA-templated14424
GO:0051262protein tetramerization330
GO:2001244positive regulation of intrinsic apoptotic signaling pathway133
GO:0003682chromatin binding12334
GO:0030308negative regulation of cell growth6113
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation175
GO:2000379positive regulation of reactive oxygen species metabolic process124
GO:0090343positive regulation of cell aging12
GO:0019903protein phosphatase binding463
GO:0034103regulation of tissue remodeling13
GO:0000060protein import into nucleus, translocation424
GO:0003700sequence-specific DNA binding transcription factor activity11748
GO:0010165response to X-ray219
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription240
GO:0008104protein localization356
GO:0016604nuclear body231
GO:1901525negative regulation of macromitophagy12
GO:0005669transcription factor TFIID complex122
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator120
GO:0002039p53 binding755
GO:0044212transcription regulatory region DNA binding6171
GO:0002931response to ischemia120
GO:0035264multicellular organism growth170
GO:0090399replicative senescence110
GO:0007275multicellular organismal development5344
GO:0007265Ras protein signal transduction375
GO:0070245positive regulation of thymocyte apoptotic process16
GO:0006461protein complex assembly6111
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process16
GO:0005759mitochondrial matrix12233
GO:0035035histone acetyltransferase binding119
GO:0097252oligodendrocyte apoptotic process12
GO:0001085RNA polymerase II transcription factor binding234
GO:0008283cell proliferation12331
GO:0071456cellular response to hypoxia498
GO:0048568embryonic organ development114
GO:0003684damaged DNA binding1151
GO:0001756somitogenesis138
GO:0009651response to salt stress214
GO:0002326B cell lineage commitment14
GO:0009303rRNA transcription112
GO:0031065positive regulation of histone deacetylation19
GO:0019901protein kinase binding21320
GO:0006355regulation of transcription, DNA-templated171104
GO:0097193intrinsic apoptotic signaling pathway455
GO:0016605PML body592
GO:0010332response to gamma radiation229
GO:0000790nuclear chromatin7133
GO:0007050cell cycle arrest7126
GO:0005657replication fork318
GO:0005654nucleoplasm831095
GO:0030971receptor tyrosine kinase binding233
GO:0035033histone deacetylase regulator activity13
GO:0030330DNA damage response, signal transduction by p53 class mediator114
GO:0046677response to antibiotic231
GO:0016032viral process55540
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator214
GO:0007369gastrulation121
GO:0002020protease binding474
GO:2000378negative regulation of reactive oxygen species metabolic process114
GO:0071850mitotic cell cycle arrest111
GO:0071158positive regulation of cell cycle arrest119
GO:0043234protein complex17300
GO:0005634nucleus1314828
GO:0034644cellular response to UV532
GO:0001701in utero embryonic development6210
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding244
GO:0042802identical protein binding18491
GO:0005737cytoplasm983976
GO:0000733DNA strand renaturation18
GO:0006974cellular response to DNA damage stimulus8158
GO:0021549cerebellum development130
GO:0006284base-excision repair739
GO:0031625ubiquitin protein ligase binding13180
GO:0005783endoplasmic reticulum9610
GO:0008340determination of adult lifespan111
GO:0005829cytosol1252562
GO:0043066negative regulation of apoptotic process30433
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator230
GO:0002360T cell lineage commitment13
GO:0005739mitochondrion241046
GO:0008156negative regulation of DNA replication121
GO:0035794positive regulation of mitochondrial membrane permeability13
GO:0045893positive regulation of transcription, DNA-templated17487
GO:0008285negative regulation of cell proliferation11367
GO:0010666positive regulation of cardiac muscle cell apoptotic process16
GO:0035690cellular response to drug250
GO:0016363nuclear matrix1192
GO:0042981regulation of apoptotic process26151
GO:0042149cellular response to glucose starvation117
GO:0000785chromatin573
GO:0002309T cell proliferation involved in immune response16
GO:0007179transforming growth factor beta receptor signaling pathway3130
GO:0005524ATP binding461354
GO:0045944positive regulation of transcription from RNA polymerase II promoter19811
GO:0051097negative regulation of helicase activity13
GO:0006983ER overload response29
GO:0031497chromatin assembly17
GO:0090403oxidative stress-induced premature senescence14
GO:0006302double-strand break repair862
GO:0031571mitotic G1 DNA damage checkpoint311
GO:0033077T cell differentiation in thymus233
GO:0006915apoptotic process34571
GO:0046902regulation of mitochondrial membrane permeability110
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2265
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway164
GO:0006289nucleotide-excision repair1269
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2151
GO:0030154cell differentiation5325
GO:0051402neuron apoptotic process236
GO:0046982protein heterodimerization activity11399
GO:0007406negative regulation of neuroblast proliferation16
GO:0032461positive regulation of protein oligomerization112
GO:0051721protein phosphatase 2A binding118
GO:0007596blood coagulation14464
GO:0005730nucleolus701684
GO:0001836release of cytochrome c from mitochondria224
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway326
GO:0047485protein N-terminus binding486
GO:0070266necroptotic process112
GO:0071479cellular response to ionizing radiation125
GO:0051087chaperone binding659
GO:0008270zinc ion binding121067
GO:0005507copper ion binding248
GO:0043065positive regulation of apoptotic process8274
GO:0007219Notch signaling pathway4125
GO:0097371MDM2/MDM4 family protein binding15
GO:0043525positive regulation of neuron apoptotic process246
GO:0048147negative regulation of fibroblast proliferation124
GO:0090200positive regulation of release of cytochrome c from mitochondria122
GO:0000122negative regulation of transcription from RNA polymerase II promoter12589
GO:0003677DNA binding261351
GO:0007569cell aging225
GO:0019899enzyme binding11288
GO:0008134transcription factor binding8246
GO:0034613cellular protein localization144