Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-4800 | wolf-screen-ratio-mammosphere-adherent | 0.833 | 7.78e-07 | 2.65e-03 | 5.08e-03 | 7 | 5 |
int-snw-2617 | wolf-screen-ratio-mammosphere-adherent | 0.927 | 3.24e-15 | 2.92e-03 | 4.51e-02 | 16 | 16 |
reg-snw-5925 | wolf-screen-ratio-mammosphere-adherent | 0.802 | 2.42e-06 | 4.82e-03 | 8.69e-03 | 8 | 5 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
ACACB | 32 | 12 | 0.656 | 1.002 | 184 | Yes | - |
GARS | 2617 | 3 | 0.076 | 0.927 | 104 | Yes | - |
SNRNP200 | 23020 | 3 | 0.538 | 0.927 | 146 | Yes | - |
PSMA3 | 5684 | 90 | 0.533 | 0.815 | 238 | Yes | - |
PPCS | 79717 | 31 | -0.569 | 0.802 | 2 | - | Yes |
UBA1 | 7317 | 6 | 0.555 | 0.971 | 207 | Yes | - |
COPA | 1314 | 7 | 0.434 | 0.833 | 170 | Yes | - |
DDX18 | 8886 | 25 | 0.660 | 1.013 | 215 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
PPIE | 10450 | 31 | 0.567 | 0.802 | 41 | - | - |
PSMC3 | 5702 | 51 | 0.719 | 1.002 | 276 | Yes | - |
HNRNPC | 3183 | 108 | 1.812 | 0.973 | 181 | Yes | - |
TP53 | 7157 | 23 | 0.432 | 0.833 | 665 | - | - |
OGDH | 4967 | 72 | 0.847 | 0.802 | 126 | Yes | - |
TFRC | 7037 | 31 | 0.730 | 0.802 | 17 | - | - |
RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 89 | 1.201 | 1.106 | 152 | Yes | - |
RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | Yes | - |
RB1 | 5925 | 31 | -0.102 | 0.802 | 351 | - | - |
RSL24D1 | 51187 | 38 | 1.300 | 1.020 | 59 | Yes | - |
CCNA2 | 890 | 54 | 0.550 | 0.973 | 246 | Yes | - |
NFYA | 4800 | 7 | 0.198 | 0.833 | 80 | - | - |
DARS | 1615 | 14 | 0.617 | 1.000 | 110 | Yes | - |
RPL14 | 9045 | 49 | 1.250 | 1.113 | 166 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
UBA1 | 7317 | SNRNP200 | 23020 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | PPCS | 79717 | pd | > | reg.pazar.txt: no annot |
COPA | 1314 | RB1 | 5925 | pd | <> | reg.ITFP.txt: no annot |
RB1 | 5925 | RPA2 | 6118 | pd | > | reg.pazar.txt: no annot |
GARS | 2617 | UBA1 | 7317 | pp | -- | int.I2D: YeastLow |
ACACB | 32 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | NFYA | 4800 | pd | < | reg.pazar.txt: no annot; reg.oreganno.txt: no annot |
PGD | 5226 | RB1 | 5925 | pd | < | reg.pazar.txt: no annot |
RPA2 | 6118 | TP53 | 7157 | pp | -- | int.Transfac: - |
ACACB | 32 | COPA | 1314 | pp | -- | int.I2D: YeastLow |
RBX1 | 9978 | PPIE | 10450 | pd | <> | reg.ITFP.txt: no annot |
DARS | 1615 | SNRNP200 | 23020 | pp | -- | int.I2D: YeastLow |
PSMC3 | 5702 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMC3 | 5702 | UBA1 | 7317 | pp | -- | int.I2D: BioGrid_Yeast |
ACACB | 32 | SNRNP200 | 23020 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
RB1 | 5925 | TP53 | 7157 | pd | < | reg.TRANSFAC.txt: no annot |
RB1 | 5925 | TP53 | 7157 | pp | -- | int.Intact: MI:0914(association) |
RPSA | 3921 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
OGDH | 4967 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
OGDH | 4967 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
PGD | 5226 | UBA1 | 7317 | pp | -- | int.I2D: YeastLow |
PSMC3 | 5702 | TP53 | 7157 | pp | -- | int.I2D: BioGrid |
DARS | 1615 | UBA1 | 7317 | pp | -- | int.I2D: YeastLow |
COPA | 1314 | OGDH | 4967 | pd | > | reg.ITFP.txt: no annot |
ACTB | 60 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
HNRNPC | 3183 | TP53 | 7157 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | COPA | 1314 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | COPA | 1314 | pp | -- | int.I2D: BioGrid_Yeast |
OGDH | 4967 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
CCNA2 | 890 | RB1 | 5925 | pp | -- | int.I2D: IntAct |
ACACB | 32 | GARS | 2617 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | GARS | 2617 | pp | -- | int.I2D: BioGrid_Yeast |
GARS | 2617 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
COPA | 1314 | RPL14 | 9045 | pd | > | reg.ITFP.txt: no annot |
ACACB | 32 | UBA1 | 7317 | pp | -- | int.I2D: Krogan_NonCore |
GARS | 2617 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
NFYA | 4800 | TP53 | 7157 | pd | > | reg.pazar.txt: no annot |
NFYA | 4800 | TP53 | 7157 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association), MI:0403(colocalization); int.I2D: BioGrid, HPRD, IntAct, BCI; int.Ravasi: -; int.HPRD: in vivo |
ACACB | 32 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast, YeastMedium |
CCNA2 | 890 | TP53 | 7157 | pp | -- | int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro |
ACTB | 60 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA3 | 5684 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast, BioGrid, YeastLow |
DARS | 1615 | PSMC3 | 5702 | pp | -- | int.I2D: BioGrid_Yeast |
DDX18 | 8886 | RSL24D1 | 51187 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast |
ACTB | 60 | DARS | 1615 | pp | -- | int.I2D: IntAct_Yeast |
DARS | 1615 | GARS | 2617 | pp | -- | int.I2D: YeastLow |
CCNA2 | 890 | NFYA | 4800 | pd | < | reg.TRANSFAC.txt: no annot |
COPA | 1314 | PSMA3 | 5684 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | TFRC | 7037 | pd | > | reg.ITFP.txt: no annot |
ACACB | 32 | DARS | 1615 | pp | -- | int.I2D: IntAct_Yeast |
GARS | 2617 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | PPIE | 10450 | pd | > | reg.pazar.txt: no annot |
GARS | 2617 | SNRNP200 | 23020 | pp | -- | int.I2D: YeastLow |
PGD | 5226 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
COPA | 1314 | NFYA | 4800 | pd | > | reg.ITFP.txt: no annot |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0005654 | nucleoplasm | 2.19e-07 | 3.58e-03 | 2.713 | 11 | 83 | 1095 |
GO:0005829 | cytosol | 5.64e-07 | 9.21e-03 | 1.934 | 15 | 125 | 2562 |
GO:0016032 | viral process | 8.97e-07 | 1.46e-02 | 3.274 | 8 | 55 | 540 |
GO:0010467 | gene expression | 4.45e-06 | 7.26e-02 | 2.965 | 8 | 58 | 669 |
GO:0044822 | poly(A) RNA binding | 1.80e-05 | 2.94e-01 | 2.446 | 9 | 50 | 1078 |
GO:0000082 | G1/S transition of mitotic cell cycle | 7.46e-05 | 1.00e+00 | 4.122 | 4 | 33 | 150 |
GO:0005515 | protein binding | 1.03e-04 | 1.00e+00 | 1.018 | 19 | 172 | 6127 |
GO:0005524 | ATP binding | 1.09e-04 | 1.00e+00 | 2.117 | 9 | 46 | 1354 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.23e-04 | 1.00e+00 | 6.891 | 2 | 3 | 11 |
GO:0070062 | extracellular vesicular exosome | 1.27e-04 | 1.00e+00 | 1.639 | 12 | 98 | 2516 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.30e-04 | 1.00e+00 | 4.913 | 3 | 22 | 65 |
GO:0016020 | membrane | 1.38e-04 | 1.00e+00 | 1.903 | 10 | 80 | 1746 |
GO:0031625 | ubiquitin protein ligase binding | 1.51e-04 | 1.00e+00 | 3.859 | 4 | 13 | 180 |
GO:0007265 | Ras protein signal transduction | 1.99e-04 | 1.00e+00 | 4.707 | 3 | 3 | 75 |
GO:0071013 | catalytic step 2 spliceosome | 2.32e-04 | 1.00e+00 | 4.632 | 3 | 7 | 79 |
GO:0000278 | mitotic cell cycle | 2.99e-04 | 1.00e+00 | 3.036 | 5 | 52 | 398 |
GO:0004004 | ATP-dependent RNA helicase activity | 3.40e-04 | 1.00e+00 | 6.181 | 2 | 2 | 18 |
GO:0016071 | mRNA metabolic process | 3.43e-04 | 1.00e+00 | 3.550 | 4 | 34 | 223 |
GO:0016605 | PML body | 3.64e-04 | 1.00e+00 | 4.412 | 3 | 5 | 92 |
GO:0016070 | RNA metabolic process | 5.04e-04 | 1.00e+00 | 3.402 | 4 | 34 | 247 |
GO:0043044 | ATP-dependent chromatin remodeling | 5.59e-04 | 1.00e+00 | 5.827 | 2 | 4 | 23 |
GO:0042802 | identical protein binding | 7.79e-04 | 1.00e+00 | 2.733 | 5 | 18 | 491 |
GO:0031492 | nucleosomal DNA binding | 8.31e-04 | 1.00e+00 | 5.543 | 2 | 4 | 28 |
GO:0000790 | nuclear chromatin | 1.07e-03 | 1.00e+00 | 3.880 | 3 | 7 | 133 |
GO:0051402 | neuron apoptotic process | 1.37e-03 | 1.00e+00 | 5.181 | 2 | 2 | 36 |
GO:0005634 | nucleus | 1.51e-03 | 1.00e+00 | 1.020 | 15 | 131 | 4828 |
GO:0006426 | glycyl-tRNA aminoacylation | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0004820 | glycine-tRNA ligase activity | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0090230 | regulation of centromere complex assembly | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0006422 | aspartyl-tRNA aminoacylation | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0004632 | phosphopantothenate--cysteine ligase activity | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 1.53e-03 | 1.00e+00 | 9.351 | 1 | 1 | 1 |
GO:0042981 | regulation of apoptotic process | 1.54e-03 | 1.00e+00 | 3.697 | 3 | 26 | 151 |
GO:0006284 | base-excision repair | 1.61e-03 | 1.00e+00 | 5.065 | 2 | 7 | 39 |
GO:0006418 | tRNA aminoacylation for protein translation | 1.87e-03 | 1.00e+00 | 4.958 | 2 | 5 | 42 |
GO:0000398 | mRNA splicing, via spliceosome | 1.98e-03 | 1.00e+00 | 3.569 | 3 | 12 | 165 |
GO:0034641 | cellular nitrogen compound metabolic process | 2.42e-03 | 1.00e+00 | 3.468 | 3 | 25 | 177 |
GO:0044281 | small molecule metabolic process | 2.62e-03 | 1.00e+00 | 1.819 | 7 | 57 | 1295 |
GO:0006521 | regulation of cellular amino acid metabolic process | 2.64e-03 | 1.00e+00 | 4.707 | 2 | 21 | 50 |
GO:0003684 | damaged DNA binding | 2.74e-03 | 1.00e+00 | 4.678 | 2 | 11 | 51 |
GO:0097252 | oligodendrocyte apoptotic process | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0045252 | oxoglutarate dehydrogenase complex | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 2 | 2 |
GO:1901525 | negative regulation of macromitophagy | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0097286 | iron ion import | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0061034 | olfactory bulb mitral cell layer development | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:2001295 | malonyl-CoA biosynthetic process | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0090343 | positive regulation of cell aging | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0004998 | transferrin receptor activity | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0003989 | acetyl-CoA carboxylase activity | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0015966 | diadenosine tetraphosphate biosynthetic process | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0000354 | cis assembly of pre-catalytic spliceosome | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0004815 | aspartate-tRNA ligase activity | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0031134 | sister chromatid biorientation | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 1 | 2 |
GO:0007070 | negative regulation of transcription from RNA polymerase II promoter during mitosis | 3.06e-03 | 1.00e+00 | 8.351 | 1 | 2 | 2 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.07e-03 | 1.00e+00 | 4.596 | 2 | 5 | 54 |
GO:0000502 | proteasome complex | 3.53e-03 | 1.00e+00 | 4.493 | 2 | 22 | 58 |
GO:0051087 | chaperone binding | 3.65e-03 | 1.00e+00 | 4.468 | 2 | 6 | 59 |
GO:0006302 | double-strand break repair | 4.03e-03 | 1.00e+00 | 4.396 | 2 | 8 | 62 |
GO:0019903 | protein phosphatase binding | 4.15e-03 | 1.00e+00 | 4.373 | 2 | 4 | 63 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.42e-03 | 1.00e+00 | 4.328 | 2 | 24 | 65 |
GO:0006084 | acetyl-CoA metabolic process | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0035794 | positive regulation of mitochondrial membrane permeability | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0071459 | protein localization to chromosome, centromeric region | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0051097 | negative regulation of helicase activity | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0035033 | histone deacetylase regulator activity | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0002360 | T cell lineage commitment | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0034103 | regulation of tissue remodeling | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | 4.59e-03 | 1.00e+00 | 7.766 | 1 | 1 | 3 |
GO:0006289 | nucleotide-excision repair | 4.96e-03 | 1.00e+00 | 4.242 | 2 | 12 | 69 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.10e-03 | 1.00e+00 | 4.221 | 2 | 24 | 70 |
GO:0005759 | mitochondrial matrix | 5.24e-03 | 1.00e+00 | 3.071 | 3 | 12 | 233 |
GO:0006412 | translation | 5.36e-03 | 1.00e+00 | 3.059 | 3 | 15 | 235 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 5.54e-03 | 1.00e+00 | 4.161 | 2 | 23 | 73 |
GO:0000785 | chromatin | 5.54e-03 | 1.00e+00 | 4.161 | 2 | 5 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.69e-03 | 1.00e+00 | 4.141 | 2 | 24 | 74 |
GO:0006767 | water-soluble vitamin metabolic process | 5.84e-03 | 1.00e+00 | 4.122 | 2 | 3 | 75 |
GO:0045893 | positive regulation of transcription, DNA-templated | 6.02e-03 | 1.00e+00 | 2.423 | 4 | 17 | 487 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0071922 | regulation of cohesin localization to chromatin | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0090403 | oxidative stress-induced premature senescence | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0004046 | aminoacylase activity | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0002326 | B cell lineage commitment | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0006104 | succinyl-CoA metabolic process | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0043550 | regulation of lipid kinase activity | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0004839 | ubiquitin activating enzyme activity | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0035189 | Rb-E2F complex | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0034349 | glial cell apoptotic process | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0034088 | maintenance of mitotic sister chromatid cohesion | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0016602 | CCAAT-binding factor complex | 6.11e-03 | 1.00e+00 | 7.351 | 1 | 1 | 4 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 6.14e-03 | 1.00e+00 | 4.084 | 2 | 23 | 77 |
GO:0006766 | vitamin metabolic process | 6.30e-03 | 1.00e+00 | 4.065 | 2 | 3 | 78 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 6.46e-03 | 1.00e+00 | 4.047 | 2 | 25 | 79 |
GO:0019083 | viral transcription | 6.78e-03 | 1.00e+00 | 4.011 | 2 | 8 | 81 |
GO:0005681 | spliceosomal complex | 7.11e-03 | 1.00e+00 | 3.976 | 2 | 3 | 83 |
GO:0047485 | protein N-terminus binding | 7.61e-03 | 1.00e+00 | 3.924 | 2 | 4 | 86 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 2 | 5 |
GO:0001940 | male pronucleus | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0019941 | modification-dependent protein catabolic process | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0009374 | biotin binding | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0097371 | MDM2/MDM4 family protein binding | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0048667 | cell morphogenesis involved in neuron differentiation | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 3 | 5 |
GO:0006734 | NADH metabolic process | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0030976 | thiamine pyrophosphate binding | 7.64e-03 | 1.00e+00 | 7.029 | 1 | 1 | 5 |
GO:0006415 | translational termination | 7.78e-03 | 1.00e+00 | 3.908 | 2 | 8 | 87 |
GO:0006414 | translational elongation | 8.85e-03 | 1.00e+00 | 3.811 | 2 | 11 | 93 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 9.03e-03 | 1.00e+00 | 3.796 | 2 | 23 | 94 |
GO:0043353 | enucleate erythrocyte differentiation | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0009108 | coenzyme biosynthetic process | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0010666 | positive regulation of cardiac muscle cell apoptotic process | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0001221 | transcription cofactor binding | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0005682 | U5 snRNP | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0002309 | T cell proliferation involved in immune response | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0045842 | positive regulation of mitotic metaphase/anaphase transition | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0021860 | pyramidal neuron development | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0021695 | cerebellar cortex development | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 4 | 6 |
GO:0070245 | positive regulation of thymocyte apoptotic process | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0007406 | negative regulation of neuroblast proliferation | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0004075 | biotin carboxylase activity | 9.16e-03 | 1.00e+00 | 6.766 | 1 | 1 | 6 |
GO:0001649 | osteoblast differentiation | 9.22e-03 | 1.00e+00 | 3.781 | 2 | 6 | 95 |
GO:0071456 | cellular response to hypoxia | 9.79e-03 | 1.00e+00 | 3.736 | 2 | 4 | 98 |
GO:0043234 | protein complex | 1.05e-02 | 1.00e+00 | 2.707 | 3 | 17 | 300 |
GO:0000028 | ribosomal small subunit assembly | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0001939 | female pronucleus | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 2 | 7 |
GO:0030157 | pancreatic juice secretion | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0030867 | rough endoplasmic reticulum membrane | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0031497 | chromatin assembly | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0016018 | cyclosporin A binding | 1.07e-02 | 1.00e+00 | 6.543 | 1 | 1 | 7 |
GO:0006200 | ATP catabolic process | 1.08e-02 | 1.00e+00 | 2.692 | 3 | 14 | 303 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.10e-02 | 1.00e+00 | 3.650 | 2 | 8 | 104 |
GO:0005730 | nucleolus | 1.11e-02 | 1.00e+00 | 1.440 | 7 | 70 | 1684 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 2 | 8 |
GO:0000733 | DNA strand renaturation | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 1 | 8 |
GO:0031325 | positive regulation of cellular metabolic process | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 1 | 8 |
GO:0006554 | lysine catabolic process | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 2 | 8 |
GO:0045116 | protein neddylation | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 2 | 8 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 1.22e-02 | 1.00e+00 | 6.351 | 1 | 5 | 8 |
GO:0006461 | protein complex assembly | 1.24e-02 | 1.00e+00 | 3.556 | 2 | 6 | 111 |
GO:0019901 | protein kinase binding | 1.25e-02 | 1.00e+00 | 2.614 | 3 | 21 | 320 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.31e-02 | 1.00e+00 | 3.518 | 2 | 10 | 114 |
GO:0019058 | viral life cycle | 1.33e-02 | 1.00e+00 | 3.505 | 2 | 10 | 115 |
GO:0000209 | protein polyubiquitination | 1.35e-02 | 1.00e+00 | 3.493 | 2 | 21 | 116 |
GO:0072562 | blood microparticle | 1.35e-02 | 1.00e+00 | 3.493 | 2 | 4 | 116 |
GO:0006853 | carnitine shuttle | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 9 |
GO:0015937 | coenzyme A biosynthetic process | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 9 |
GO:0097284 | hepatocyte apoptotic process | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 2 | 9 |
GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 2 | 9 |
GO:0031065 | positive regulation of histone deacetylation | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 9 |
GO:0000075 | cell cycle checkpoint | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 2 | 9 |
GO:0006768 | biotin metabolic process | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:0090399 | replicative senescence | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:2000648 | positive regulation of stem cell proliferation | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:0015939 | pantothenate metabolic process | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:0046902 | regulation of mitochondrial membrane permeability | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:0021756 | striatum development | 1.52e-02 | 1.00e+00 | 6.029 | 1 | 1 | 10 |
GO:0007219 | Notch signaling pathway | 1.56e-02 | 1.00e+00 | 3.385 | 2 | 4 | 125 |
GO:0007050 | cell cycle arrest | 1.58e-02 | 1.00e+00 | 3.373 | 2 | 7 | 126 |
GO:0003723 | RNA binding | 1.65e-02 | 1.00e+00 | 2.464 | 3 | 19 | 355 |
GO:0006098 | pentose-phosphate shunt | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 3 | 11 |
GO:0008340 | determination of adult lifespan | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 11 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 11 |
GO:0071850 | mitotic cell cycle arrest | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 11 |
GO:0042551 | neuron maturation | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 11 |
GO:0045651 | positive regulation of macrophage differentiation | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 11 |
GO:0045120 | pronucleus | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 11 |
GO:0033762 | response to glucagon | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 11 |
GO:2000036 | regulation of stem cell maintenance | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 11 |
GO:0006413 | translational initiation | 1.70e-02 | 1.00e+00 | 3.317 | 2 | 12 | 131 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 2 | 12 |
GO:0051146 | striated muscle cell differentiation | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 12 |
GO:0021794 | thalamus development | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 12 |
GO:0070266 | necroptotic process | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 12 |
GO:0032461 | positive regulation of protein oligomerization | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 12 |
GO:0009303 | rRNA transcription | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 12 |
GO:0044255 | cellular lipid metabolic process | 1.93e-02 | 1.00e+00 | 3.221 | 2 | 4 | 140 |
GO:0003735 | structural constituent of ribosome | 1.95e-02 | 1.00e+00 | 3.211 | 2 | 8 | 141 |
GO:0042273 | ribosomal large subunit biogenesis | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 4 | 13 |
GO:0005662 | DNA replication factor A complex | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 3 | 13 |
GO:0045780 | positive regulation of bone resorption | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 1 | 13 |
GO:0048205 | COPI coating of Golgi vesicle | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 1 | 13 |
GO:0030126 | COPI vesicle coat | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 1 | 13 |
GO:0008266 | poly(U) RNA binding | 1.97e-02 | 1.00e+00 | 5.650 | 1 | 1 | 13 |
GO:0061024 | membrane organization | 2.08e-02 | 1.00e+00 | 3.161 | 2 | 5 | 146 |
GO:0035267 | NuA4 histone acetyltransferase complex | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 4 | 14 |
GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 2 | 14 |
GO:2000378 | negative regulation of reactive oxygen species metabolic process | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 1 | 14 |
GO:0030330 | DNA damage response, signal transduction by p53 class mediator | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 1 | 14 |
GO:0007095 | mitotic G2 DNA damage checkpoint | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 1 | 14 |
GO:0009651 | response to salt stress | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 2 | 14 |
GO:0048568 | embryonic organ development | 2.12e-02 | 1.00e+00 | 5.543 | 1 | 1 | 14 |
GO:0006457 | protein folding | 2.16e-02 | 1.00e+00 | 3.131 | 2 | 8 | 149 |
GO:0045445 | myoblast differentiation | 2.27e-02 | 1.00e+00 | 5.444 | 1 | 2 | 15 |
GO:0016514 | SWI/SNF complex | 2.27e-02 | 1.00e+00 | 5.444 | 1 | 3 | 15 |
GO:0006974 | cellular response to DNA damage stimulus | 2.41e-02 | 1.00e+00 | 3.047 | 2 | 8 | 158 |
GO:0050998 | nitric-oxide synthase binding | 2.42e-02 | 1.00e+00 | 5.351 | 1 | 1 | 16 |
GO:0006103 | 2-oxoglutarate metabolic process | 2.42e-02 | 1.00e+00 | 5.351 | 1 | 1 | 16 |
GO:0042149 | cellular response to glucose starvation | 2.57e-02 | 1.00e+00 | 5.263 | 1 | 1 | 17 |
GO:0045070 | positive regulation of viral genome replication | 2.57e-02 | 1.00e+00 | 5.263 | 1 | 1 | 17 |
GO:0022624 | proteasome accessory complex | 2.57e-02 | 1.00e+00 | 5.263 | 1 | 9 | 17 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2.71e-02 | 1.00e+00 | 2.958 | 2 | 5 | 168 |
GO:0035861 | site of double-strand break | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 18 |
GO:0051721 | protein phosphatase 2A binding | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 18 |
GO:0005839 | proteasome core complex | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 11 | 18 |
GO:0005657 | replication fork | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 3 | 18 |
GO:0043066 | negative regulation of apoptotic process | 2.77e-02 | 1.00e+00 | 2.177 | 3 | 30 | 433 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.87e-02 | 1.00e+00 | 5.103 | 1 | 1 | 19 |
GO:0035035 | histone acetyltransferase binding | 2.87e-02 | 1.00e+00 | 5.103 | 1 | 1 | 19 |
GO:0071158 | positive regulation of cell cycle arrest | 2.87e-02 | 1.00e+00 | 5.103 | 1 | 1 | 19 |
GO:1903506 | regulation of nucleic acid-templated transcription | 2.87e-02 | 1.00e+00 | 5.103 | 1 | 1 | 19 |
GO:0010165 | response to X-ray | 2.87e-02 | 1.00e+00 | 5.103 | 1 | 2 | 19 |
GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 3.02e-02 | 1.00e+00 | 5.029 | 1 | 2 | 20 |
GO:0004298 | threonine-type endopeptidase activity | 3.02e-02 | 1.00e+00 | 5.029 | 1 | 11 | 20 |
GO:0002931 | response to ischemia | 3.02e-02 | 1.00e+00 | 5.029 | 1 | 1 | 20 |
GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator | 3.02e-02 | 1.00e+00 | 5.029 | 1 | 1 | 20 |
GO:0006298 | mismatch repair | 3.02e-02 | 1.00e+00 | 5.029 | 1 | 6 | 20 |
GO:0008156 | negative regulation of DNA replication | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 1 | 21 |
GO:0007369 | gastrulation | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 5 | 21 |
GO:0030316 | osteoclast differentiation | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 22 |
GO:0000792 | heterochromatin | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 22 |
GO:0005669 | transcription factor TFIID complex | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 1 | 22 |
GO:0090200 | positive regulation of release of cytochrome c from mitochondria | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 1 | 22 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 5 | 22 |
GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 3 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 4 | 22 |
GO:0030057 | desmosome | 3.47e-02 | 1.00e+00 | 4.827 | 1 | 1 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 3.47e-02 | 1.00e+00 | 4.827 | 1 | 2 | 23 |
GO:0043236 | laminin binding | 3.47e-02 | 1.00e+00 | 4.827 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 3.47e-02 | 1.00e+00 | 4.827 | 1 | 1 | 23 |
GO:0045879 | negative regulation of smoothened signaling pathway | 3.47e-02 | 1.00e+00 | 4.827 | 1 | 1 | 23 |
GO:0001836 | release of cytochrome c from mitochondria | 3.61e-02 | 1.00e+00 | 4.766 | 1 | 2 | 24 |
GO:0048147 | negative regulation of fibroblast proliferation | 3.61e-02 | 1.00e+00 | 4.766 | 1 | 1 | 24 |
GO:0000060 | protein import into nucleus, translocation | 3.61e-02 | 1.00e+00 | 4.766 | 1 | 4 | 24 |
GO:2000379 | positive regulation of reactive oxygen species metabolic process | 3.61e-02 | 1.00e+00 | 4.766 | 1 | 1 | 24 |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | 3.76e-02 | 1.00e+00 | 4.707 | 1 | 1 | 25 |
GO:0007569 | cell aging | 3.76e-02 | 1.00e+00 | 4.707 | 1 | 2 | 25 |
GO:0071479 | cellular response to ionizing radiation | 3.76e-02 | 1.00e+00 | 4.707 | 1 | 1 | 25 |
GO:0044267 | cellular protein metabolic process | 3.89e-02 | 1.00e+00 | 1.984 | 3 | 24 | 495 |
GO:1900740 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 3.91e-02 | 1.00e+00 | 4.650 | 1 | 3 | 26 |
GO:0000722 | telomere maintenance via recombination | 3.91e-02 | 1.00e+00 | 4.650 | 1 | 7 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 3.91e-02 | 1.00e+00 | 4.650 | 1 | 2 | 26 |
GO:0048565 | digestive tract development | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 27 |
GO:0001046 | core promoter sequence-specific DNA binding | 4.20e-02 | 1.00e+00 | 4.543 | 1 | 1 | 28 |
GO:0043022 | ribosome binding | 4.20e-02 | 1.00e+00 | 4.543 | 1 | 3 | 28 |
GO:0019894 | kinesin binding | 4.20e-02 | 1.00e+00 | 4.543 | 1 | 1 | 28 |
GO:0006099 | tricarboxylic acid cycle | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 3 | 29 |
GO:0019005 | SCF ubiquitin ligase complex | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 1 | 29 |
GO:0010332 | response to gamma radiation | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 2 | 29 |
GO:0003730 | mRNA 3'-UTR binding | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 2 | 29 |
GO:0051262 | protein tetramerization | 4.50e-02 | 1.00e+00 | 4.444 | 1 | 3 | 30 |
GO:0042254 | ribosome biogenesis | 4.50e-02 | 1.00e+00 | 4.444 | 1 | 1 | 30 |
GO:0021549 | cerebellum development | 4.50e-02 | 1.00e+00 | 4.444 | 1 | 1 | 30 |
GO:0007346 | regulation of mitotic cell cycle | 4.50e-02 | 1.00e+00 | 4.444 | 1 | 3 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 4.50e-02 | 1.00e+00 | 4.444 | 1 | 2 | 30 |
GO:0046677 | response to antibiotic | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 2 | 31 |
GO:0016604 | nuclear body | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 2 | 31 |
GO:0006271 | DNA strand elongation involved in DNA replication | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 9 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 4.65e-02 | 1.00e+00 | 4.396 | 1 | 2 | 31 |
GO:0050661 | NADP binding | 4.79e-02 | 1.00e+00 | 4.351 | 1 | 1 | 32 |
GO:0051219 | phosphoprotein binding | 4.79e-02 | 1.00e+00 | 4.351 | 1 | 3 | 32 |
GO:0034644 | cellular response to UV | 4.79e-02 | 1.00e+00 | 4.351 | 1 | 5 | 32 |
GO:0033572 | transferrin transport | 4.79e-02 | 1.00e+00 | 4.351 | 1 | 6 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 4.79e-02 | 1.00e+00 | 4.351 | 1 | 2 | 32 |
GO:0008380 | RNA splicing | 4.87e-02 | 1.00e+00 | 2.493 | 2 | 13 | 232 |
GO:0030971 | receptor tyrosine kinase binding | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 2 | 33 |
GO:0033077 | T cell differentiation in thymus | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 2 | 33 |
GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 1 | 33 |
GO:0031072 | heat shock protein binding | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 2 | 33 |
GO:0000413 | protein peptidyl-prolyl isomerization | 5.08e-02 | 1.00e+00 | 4.263 | 1 | 1 | 34 |
GO:0001085 | RNA polymerase II transcription factor binding | 5.08e-02 | 1.00e+00 | 4.263 | 1 | 2 | 34 |
GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | 5.08e-02 | 1.00e+00 | 4.263 | 1 | 1 | 34 |
GO:0003713 | transcription coactivator activity | 5.14e-02 | 1.00e+00 | 2.450 | 2 | 10 | 239 |
GO:0034332 | adherens junction organization | 5.37e-02 | 1.00e+00 | 4.181 | 1 | 1 | 36 |
GO:0001895 | retina homeostasis | 5.37e-02 | 1.00e+00 | 4.181 | 1 | 1 | 36 |
GO:0008134 | transcription factor binding | 5.41e-02 | 1.00e+00 | 2.408 | 2 | 8 | 246 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 5.52e-02 | 1.00e+00 | 4.141 | 1 | 4 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 5.52e-02 | 1.00e+00 | 4.141 | 1 | 4 | 37 |
GO:0006633 | fatty acid biosynthetic process | 5.52e-02 | 1.00e+00 | 4.141 | 1 | 2 | 37 |
GO:0006915 | apoptotic process | 5.54e-02 | 1.00e+00 | 1.778 | 3 | 34 | 571 |
GO:0001756 | somitogenesis | 5.67e-02 | 1.00e+00 | 4.103 | 1 | 1 | 38 |
GO:0070527 | platelet aggregation | 5.67e-02 | 1.00e+00 | 4.103 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 5.67e-02 | 1.00e+00 | 4.103 | 1 | 4 | 38 |
GO:0004842 | ubiquitin-protein transferase activity | 5.80e-02 | 1.00e+00 | 2.351 | 2 | 4 | 256 |
GO:0021766 | hippocampus development | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 4 | 39 |
GO:0008026 | ATP-dependent helicase activity | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 3 | 39 |
GO:0006096 | glycolytic process | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 4 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 5.81e-02 | 1.00e+00 | 4.065 | 1 | 3 | 39 |
GO:0000781 | chromosome, telomeric region | 5.95e-02 | 1.00e+00 | 4.029 | 1 | 2 | 40 |
GO:0001228 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 5.95e-02 | 1.00e+00 | 4.029 | 1 | 2 | 40 |
GO:0030521 | androgen receptor signaling pathway | 6.10e-02 | 1.00e+00 | 3.993 | 1 | 2 | 41 |
GO:0005737 | cytoplasm | 6.11e-02 | 1.00e+00 | 0.715 | 10 | 98 | 3976 |
GO:0006281 | DNA repair | 6.13e-02 | 1.00e+00 | 2.306 | 2 | 22 | 264 |
GO:0035914 | skeletal muscle cell differentiation | 6.24e-02 | 1.00e+00 | 3.958 | 1 | 1 | 42 |
GO:0014070 | response to organic cyclic compound | 6.39e-02 | 1.00e+00 | 3.924 | 1 | 3 | 43 |
GO:0000166 | nucleotide binding | 6.46e-02 | 1.00e+00 | 2.263 | 2 | 6 | 272 |
GO:0048146 | positive regulation of fibroblast proliferation | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 2 | 44 |
GO:0034613 | cellular protein localization | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 1 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 2 | 44 |
GO:0021762 | substantia nigra development | 6.82e-02 | 1.00e+00 | 3.827 | 1 | 1 | 46 |
GO:0001047 | core promoter binding | 6.82e-02 | 1.00e+00 | 3.827 | 1 | 2 | 46 |
GO:0043525 | positive regulation of neuron apoptotic process | 6.82e-02 | 1.00e+00 | 3.827 | 1 | 2 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 6.82e-02 | 1.00e+00 | 3.827 | 1 | 8 | 46 |
GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 6.96e-02 | 1.00e+00 | 3.796 | 1 | 3 | 47 |
GO:0048511 | rhythmic process | 6.96e-02 | 1.00e+00 | 3.796 | 1 | 2 | 47 |
GO:0005507 | copper ion binding | 7.10e-02 | 1.00e+00 | 3.766 | 1 | 2 | 48 |
GO:0019899 | enzyme binding | 7.14e-02 | 1.00e+00 | 2.181 | 2 | 11 | 288 |
GO:0005739 | mitochondrion | 7.25e-02 | 1.00e+00 | 1.320 | 4 | 24 | 1046 |
GO:0022625 | cytosolic large ribosomal subunit | 7.25e-02 | 1.00e+00 | 3.736 | 1 | 5 | 49 |
GO:0031100 | organ regeneration | 7.39e-02 | 1.00e+00 | 3.707 | 1 | 4 | 50 |
GO:0035690 | cellular response to drug | 7.39e-02 | 1.00e+00 | 3.707 | 1 | 2 | 50 |
GO:0006091 | generation of precursor metabolites and energy | 7.53e-02 | 1.00e+00 | 3.678 | 1 | 3 | 51 |
GO:0005905 | coated pit | 7.53e-02 | 1.00e+00 | 3.678 | 1 | 2 | 51 |
GO:0016567 | protein ubiquitination | 7.61e-02 | 1.00e+00 | 2.127 | 2 | 5 | 299 |
GO:0003725 | double-stranded RNA binding | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 6 | 54 |
GO:0019900 | kinase binding | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 54 |
GO:0050680 | negative regulation of epithelial cell proliferation | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 54 |
GO:0051289 | protein homotetramerization | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 54 |
GO:0097193 | intrinsic apoptotic signaling pathway | 8.10e-02 | 1.00e+00 | 3.569 | 1 | 4 | 55 |
GO:0002039 | p53 binding | 8.10e-02 | 1.00e+00 | 3.569 | 1 | 7 | 55 |
GO:0000932 | cytoplasmic mRNA processing body | 8.24e-02 | 1.00e+00 | 3.543 | 1 | 3 | 56 |
GO:0008104 | protein localization | 8.24e-02 | 1.00e+00 | 3.543 | 1 | 3 | 56 |
GO:0006879 | cellular iron ion homeostasis | 8.38e-02 | 1.00e+00 | 3.518 | 1 | 5 | 57 |
GO:0000724 | double-strand break repair via homologous recombination | 8.38e-02 | 1.00e+00 | 3.518 | 1 | 6 | 57 |
GO:0012505 | endomembrane system | 8.38e-02 | 1.00e+00 | 3.518 | 1 | 2 | 57 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 8.66e-02 | 1.00e+00 | 3.468 | 1 | 4 | 59 |
GO:0045216 | cell-cell junction organization | 8.66e-02 | 1.00e+00 | 3.468 | 1 | 2 | 59 |
GO:0000723 | telomere maintenance | 8.66e-02 | 1.00e+00 | 3.468 | 1 | 8 | 59 |
GO:0031966 | mitochondrial membrane | 8.66e-02 | 1.00e+00 | 3.468 | 1 | 1 | 59 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 9.36e-02 | 1.00e+00 | 3.351 | 1 | 1 | 64 |
GO:0006469 | negative regulation of protein kinase activity | 9.50e-02 | 1.00e+00 | 3.328 | 1 | 2 | 65 |
GO:0001558 | regulation of cell growth | 9.64e-02 | 1.00e+00 | 3.306 | 1 | 4 | 66 |
GO:0030141 | secretory granule | 9.78e-02 | 1.00e+00 | 3.284 | 1 | 2 | 67 |
GO:0006338 | chromatin remodeling | 9.92e-02 | 1.00e+00 | 3.263 | 1 | 4 | 68 |
GO:0003697 | single-stranded DNA binding | 1.01e-01 | 1.00e+00 | 3.242 | 1 | 9 | 69 |
GO:0035264 | multicellular organism growth | 1.02e-01 | 1.00e+00 | 3.221 | 1 | 1 | 70 |
GO:0034329 | cell junction assembly | 1.03e-01 | 1.00e+00 | 3.201 | 1 | 1 | 71 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.05e-01 | 1.00e+00 | 1.389 | 3 | 11 | 748 |
GO:0055037 | recycling endosome | 1.06e-01 | 1.00e+00 | 3.161 | 1 | 2 | 73 |
GO:0032355 | response to estradiol | 1.06e-01 | 1.00e+00 | 3.161 | 1 | 5 | 73 |
GO:0002020 | protease binding | 1.07e-01 | 1.00e+00 | 3.141 | 1 | 4 | 74 |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 1.09e-01 | 1.00e+00 | 3.122 | 1 | 1 | 75 |
GO:0031175 | neuron projection development | 1.09e-01 | 1.00e+00 | 3.122 | 1 | 1 | 75 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.10e-01 | 1.00e+00 | 3.103 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.12e-01 | 1.00e+00 | 3.084 | 1 | 5 | 77 |
GO:0005179 | hormone activity | 1.21e-01 | 1.00e+00 | 2.958 | 1 | 1 | 84 |
GO:0006898 | receptor-mediated endocytosis | 1.24e-01 | 1.00e+00 | 2.924 | 1 | 2 | 86 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.25e-01 | 1.00e+00 | 1.272 | 3 | 19 | 811 |
GO:0016363 | nuclear matrix | 1.32e-01 | 1.00e+00 | 2.827 | 1 | 11 | 92 |
GO:0042470 | melanosome | 1.32e-01 | 1.00e+00 | 2.827 | 1 | 10 | 92 |
GO:0006928 | cellular component movement | 1.32e-01 | 1.00e+00 | 2.827 | 1 | 7 | 92 |
GO:0005200 | structural constituent of cytoskeleton | 1.33e-01 | 1.00e+00 | 2.811 | 1 | 7 | 93 |
GO:0045892 | negative regulation of transcription, DNA-templated | 1.37e-01 | 1.00e+00 | 1.623 | 2 | 14 | 424 |
GO:0006364 | rRNA processing | 1.37e-01 | 1.00e+00 | 2.766 | 1 | 5 | 96 |
GO:0006112 | energy reserve metabolic process | 1.41e-01 | 1.00e+00 | 2.721 | 1 | 1 | 99 |
GO:0014069 | postsynaptic density | 1.50e-01 | 1.00e+00 | 2.623 | 1 | 1 | 106 |
GO:0016023 | cytoplasmic membrane-bounded vesicle | 1.52e-01 | 1.00e+00 | 2.609 | 1 | 3 | 107 |
GO:0005741 | mitochondrial outer membrane | 1.53e-01 | 1.00e+00 | 2.596 | 1 | 4 | 108 |
GO:0042127 | regulation of cell proliferation | 1.57e-01 | 1.00e+00 | 2.556 | 1 | 4 | 111 |
GO:0007596 | blood coagulation | 1.58e-01 | 1.00e+00 | 1.493 | 2 | 14 | 464 |
GO:0030308 | negative regulation of cell growth | 1.60e-01 | 1.00e+00 | 2.530 | 1 | 6 | 113 |
GO:0030529 | ribonucleoprotein complex | 1.61e-01 | 1.00e+00 | 2.518 | 1 | 8 | 114 |
GO:0005819 | spindle | 1.61e-01 | 1.00e+00 | 2.518 | 1 | 7 | 114 |
GO:0044237 | cellular metabolic process | 1.66e-01 | 1.00e+00 | 2.468 | 1 | 3 | 118 |
GO:0006325 | chromatin organization | 1.72e-01 | 1.00e+00 | 2.408 | 1 | 4 | 123 |
GO:0006260 | DNA replication | 1.75e-01 | 1.00e+00 | 2.385 | 1 | 12 | 125 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.81e-01 | 1.00e+00 | 2.328 | 1 | 3 | 130 |
GO:0046983 | protein dimerization activity | 1.83e-01 | 1.00e+00 | 2.317 | 1 | 3 | 131 |
GO:0031982 | vesicle | 1.86e-01 | 1.00e+00 | 2.284 | 1 | 10 | 134 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.90e-01 | 1.00e+00 | 2.253 | 1 | 7 | 137 |
GO:0005615 | extracellular space | 1.99e-01 | 1.00e+00 | 0.955 | 3 | 17 | 1010 |
GO:0016887 | ATPase activity | 1.99e-01 | 1.00e+00 | 2.181 | 1 | 7 | 144 |
GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 2.07e-01 | 1.00e+00 | 2.112 | 1 | 2 | 151 |
GO:0010008 | endosome membrane | 2.15e-01 | 1.00e+00 | 2.056 | 1 | 6 | 157 |
GO:0005198 | structural molecule activity | 2.17e-01 | 1.00e+00 | 2.038 | 1 | 4 | 159 |
GO:0044212 | transcription regulatory region DNA binding | 2.32e-01 | 1.00e+00 | 1.933 | 1 | 6 | 171 |
GO:0030424 | axon | 2.33e-01 | 1.00e+00 | 1.924 | 1 | 3 | 172 |
GO:0006886 | intracellular protein transport | 2.34e-01 | 1.00e+00 | 1.916 | 1 | 4 | 173 |
GO:0005768 | endosome | 2.35e-01 | 1.00e+00 | 1.908 | 1 | 5 | 174 |
GO:0006355 | regulation of transcription, DNA-templated | 2.37e-01 | 1.00e+00 | 0.827 | 3 | 17 | 1104 |
GO:0003714 | transcription corepressor activity | 2.41e-01 | 1.00e+00 | 1.867 | 1 | 7 | 179 |
GO:0009897 | external side of plasma membrane | 2.46e-01 | 1.00e+00 | 1.835 | 1 | 4 | 183 |
GO:0032403 | protein complex binding | 2.48e-01 | 1.00e+00 | 1.819 | 1 | 7 | 185 |
GO:0001701 | in utero embryonic development | 2.77e-01 | 1.00e+00 | 1.636 | 1 | 6 | 210 |
GO:0005765 | lysosomal membrane | 2.86e-01 | 1.00e+00 | 1.582 | 1 | 5 | 218 |
GO:0007067 | mitotic nuclear division | 3.00e-01 | 1.00e+00 | 1.499 | 1 | 13 | 231 |
GO:0003677 | DNA binding | 3.43e-01 | 1.00e+00 | 0.536 | 3 | 26 | 1351 |
GO:0005975 | carbohydrate metabolic process | 3.45e-01 | 1.00e+00 | 1.253 | 1 | 5 | 274 |
GO:0043065 | positive regulation of apoptotic process | 3.45e-01 | 1.00e+00 | 1.253 | 1 | 8 | 274 |
GO:0042493 | response to drug | 3.59e-01 | 1.00e+00 | 1.181 | 1 | 11 | 288 |
GO:0005856 | cytoskeleton | 3.82e-01 | 1.00e+00 | 1.070 | 1 | 8 | 311 |
GO:0030154 | cell differentiation | 3.95e-01 | 1.00e+00 | 1.006 | 1 | 5 | 325 |
GO:0007411 | axon guidance | 3.97e-01 | 1.00e+00 | 0.997 | 1 | 9 | 327 |
GO:0008283 | cell proliferation | 4.01e-01 | 1.00e+00 | 0.980 | 1 | 12 | 331 |
GO:0043231 | intracellular membrane-bounded organelle | 4.02e-01 | 1.00e+00 | 0.976 | 1 | 8 | 332 |
GO:0003682 | chromatin binding | 4.04e-01 | 1.00e+00 | 0.967 | 1 | 12 | 334 |
GO:0007275 | multicellular organismal development | 4.13e-01 | 1.00e+00 | 0.924 | 1 | 5 | 344 |
GO:0008285 | negative regulation of cell proliferation | 4.34e-01 | 1.00e+00 | 0.831 | 1 | 11 | 367 |
GO:0005925 | focal adhesion | 4.37e-01 | 1.00e+00 | 0.819 | 1 | 18 | 370 |
GO:0007155 | cell adhesion | 4.49e-01 | 1.00e+00 | 0.766 | 1 | 8 | 384 |
GO:0046982 | protein heterodimerization activity | 4.62e-01 | 1.00e+00 | 0.710 | 1 | 11 | 399 |
GO:0009986 | cell surface | 4.81e-01 | 1.00e+00 | 0.629 | 1 | 9 | 422 |
GO:0006366 | transcription from RNA polymerase II promoter | 4.83e-01 | 1.00e+00 | 0.619 | 1 | 12 | 425 |
GO:0008270 | zinc ion binding | 4.93e-01 | 1.00e+00 | 0.291 | 2 | 12 | 1067 |
GO:0055114 | oxidation-reduction process | 5.27e-01 | 1.00e+00 | 0.441 | 1 | 11 | 481 |
GO:0055085 | transmembrane transport | 5.51e-01 | 1.00e+00 | 0.345 | 1 | 8 | 514 |
GO:0048471 | perinuclear region of cytoplasm | 5.57e-01 | 1.00e+00 | 0.320 | 1 | 12 | 523 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 6.01e-01 | 1.00e+00 | 0.148 | 1 | 12 | 589 |
GO:0005783 | endoplasmic reticulum | 6.14e-01 | 1.00e+00 | 0.098 | 1 | 9 | 610 |
GO:0045087 | innate immune response | 6.18e-01 | 1.00e+00 | 0.084 | 1 | 20 | 616 |
GO:0046872 | metal ion binding | 6.70e-01 | 1.00e+00 | -0.166 | 2 | 24 | 1465 |
GO:0005887 | integral component of plasma membrane | 7.81e-01 | 1.00e+00 | -0.558 | 1 | 7 | 961 |
GO:0005576 | extracellular region | 8.10e-01 | 1.00e+00 | -0.684 | 1 | 9 | 1049 |
GO:0006351 | transcription, DNA-templated | 9.22e-01 | 1.00e+00 | -1.280 | 1 | 25 | 1585 |
GO:0005886 | plasma membrane | 9.47e-01 | 1.00e+00 | -1.118 | 2 | 38 | 2834 |