reg-snw-4800

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.833 7.78e-07 2.65e-03 5.08e-03
wolf-screen-ratio-mammosphere-adherent-reg-snw-4800 subnetwork

Genes (7)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
ACTB 60 21.1530.83323-Yes-
[ NFYA ] 4800 10.1980.83380TF--
CCNA2 890 100.5500.973246TFYes-
COPA 1314 10.4340.833170TFYes-
RPL14 9045 31.2500.83323-Yes-
TP53 7157 20.4320.833101TF--
HNRNPC 3183 401.8120.97362-Yes-

Interactions (7)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
ACTB 60 COPA 1314 pd < reg.ITFP.txt: no annot
HNRNPC 3183 TP53 7157 pd < reg.ITFP.txt: no annot
CCNA2 890 NFYA 4800 pd < reg.TRANSFAC.txt: no annot
ACTB 60 NFYA 4800 pd < reg.pazar.txt: no annot;
reg.oreganno.txt: no annot
COPA 1314 RPL14 9045 pd > reg.ITFP.txt: no annot
COPA 1314 NFYA 4800 pd > reg.ITFP.txt: no annot
NFYA 4800 TP53 7157 pd > reg.pazar.txt: no annot

Related GO terms (228)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000790nuclear chromatin4.58e-054.48e-015.26333109
GO:0043044ATP-dependent chromatin remodeling8.32e-058.12e-017.1242220
GO:0005654nucleoplasm1.03e-041.00e+002.993555876
GO:0031492nucleosomal DNA binding1.31e-041.00e+006.8022225
GO:0043234protein complex3.22e-041.00e+004.31738210
GO:0019901protein kinase binding4.32e-041.00e+004.173311232
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.10e-041.00e+005.8312349
GO:0097252oligodendrocyte apoptotic process7.17e-041.00e+0010.446111
GO:0090343positive regulation of cell aging7.17e-041.00e+0010.446111
GO:0034103regulation of tissue remodeling7.17e-041.00e+0010.446111
GO:0007265Ras protein signal transduction7.39e-041.00e+005.5632359
GO:0090403oxidative stress-induced premature senescence1.43e-031.00e+009.446112
GO:1901525negative regulation of macromitophagy1.43e-031.00e+009.446112
GO:0035794positive regulation of mitochondrial membrane permeability1.43e-031.00e+009.446112
GO:0061024membrane organization1.67e-031.00e+004.9702289
GO:0045893positive regulation of transcription, DNA-templated1.78e-031.00e+003.473310377
GO:0010666positive regulation of cardiac muscle cell apoptotic process2.15e-031.00e+008.861113
GO:0035033histone deacetylase regulator activity2.15e-031.00e+008.861113
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process2.15e-031.00e+008.861113
GO:0002360T cell lineage commitment2.15e-031.00e+008.861113
GO:0051097negative regulation of helicase activity2.15e-031.00e+008.861113
GO:0030157pancreatic juice secretion2.86e-031.00e+008.446114
GO:0001940male pronucleus2.86e-031.00e+008.446114
GO:0002326B cell lineage commitment2.86e-031.00e+008.446114
GO:0070245positive regulation of thymocyte apoptotic process2.86e-031.00e+008.446114
GO:0016602CCAAT-binding factor complex2.86e-031.00e+008.446114
GO:0005829cytosol3.09e-031.00e+001.9655581787
GO:0001221transcription cofactor binding3.58e-031.00e+008.124115
GO:0030957Tat protein binding3.58e-031.00e+008.124125
GO:0002309T cell proliferation involved in immune response3.58e-031.00e+008.124115
GO:0001939female pronucleus3.58e-031.00e+008.124115
GO:0097371MDM2/MDM4 family protein binding3.58e-031.00e+008.124115
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding4.20e-031.00e+004.29622142
GO:0006983ER overload response4.29e-031.00e+007.861116
GO:0031497chromatin assembly4.29e-031.00e+007.861116
GO:0007406negative regulation of neuroblast proliferation4.29e-031.00e+007.861116
GO:0070688MLL5-L complex4.29e-031.00e+007.861116
GO:2000648positive regulation of stem cell proliferation5.01e-031.00e+007.639117
GO:0010389regulation of G2/M transition of mitotic cell cycle5.01e-031.00e+007.639117
GO:0033762response to glucagon5.01e-031.00e+007.639117
GO:0030126COPI vesicle coat5.01e-031.00e+007.639117
GO:0090399replicative senescence5.01e-031.00e+007.639127
GO:0000733DNA strand renaturation5.72e-031.00e+007.446128
GO:0009303rRNA transcription5.72e-031.00e+007.446118
GO:0016020membrane5.97e-031.00e+002.2094381207
GO:0031065positive regulation of histone deacetylation6.44e-031.00e+007.276119
GO:0070266necroptotic process6.44e-031.00e+007.276119
GO:0031571mitotic G1 DNA damage checkpoint6.44e-031.00e+007.276129
GO:0046902regulation of mitochondrial membrane permeability6.44e-031.00e+007.276119
GO:0008266poly(U) RNA binding6.44e-031.00e+007.276119
GO:0050998nitric-oxide synthase binding7.15e-031.00e+007.1241110
GO:0071850mitotic cell cycle arrest7.15e-031.00e+007.1241110
GO:0032461positive regulation of protein oligomerization7.15e-031.00e+007.1241110
GO:0009651response to salt stress7.15e-031.00e+007.1241110
GO:0042273ribosomal large subunit biogenesis7.86e-031.00e+006.9871311
GO:00709353'-UTR-mediated mRNA stabilization7.86e-031.00e+006.9871211
GO:0042149cellular response to glucose starvation7.86e-031.00e+006.9871111
GO:0008340determination of adult lifespan7.86e-031.00e+006.9871111
GO:2000036regulation of stem cell maintenance7.86e-031.00e+006.9871211
GO:0048568embryonic organ development7.86e-031.00e+006.9871111
GO:0045120pronucleus7.86e-031.00e+006.9871111
GO:0035267NuA4 histone acetyltransferase complex8.57e-031.00e+006.8611312
GO:0048205COPI coating of Golgi vesicle8.57e-031.00e+006.8611112
GO:2000378negative regulation of reactive oxygen species metabolic process8.57e-031.00e+006.8611112
GO:0030330DNA damage response, signal transduction by p53 class mediator9.28e-031.00e+006.7461113
GO:0007095mitotic G2 DNA damage checkpoint9.28e-031.00e+006.7461113
GO:0002931response to ischemia9.28e-031.00e+006.7461113
GO:0008156negative regulation of DNA replication9.28e-031.00e+006.7461113
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator1.00e-021.00e+006.6391114
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator1.00e-021.00e+006.6391114
GO:0051721protein phosphatase 2A binding1.00e-021.00e+006.6391114
GO:0030863cortical cytoskeleton1.07e-021.00e+006.5391115
GO:0071158positive regulation of cell cycle arrest1.07e-021.00e+006.5391115
GO:0005657replication fork1.14e-021.00e+006.4461216
GO:0010165response to X-ray1.21e-021.00e+006.3591117
GO:0035035histone acetyltransferase binding1.21e-021.00e+006.3591117
GO:0007369gastrulation1.21e-021.00e+006.3591117
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.21e-021.00e+006.3591117
GO:0003723RNA binding1.23e-021.00e+003.498211247
GO:0005669transcription factor TFIID complex1.28e-021.00e+006.2761118
GO:0048147negative regulation of fibroblast proliferation1.28e-021.00e+006.2761118
GO:0090200positive regulation of release of cytochrome c from mitochondria1.28e-021.00e+006.2761118
GO:0021549cerebellum development1.35e-021.00e+006.1981119
GO:0000060protein import into nucleus, translocation1.35e-021.00e+006.1981119
GO:0036464cytoplasmic ribonucleoprotein granule1.35e-021.00e+006.1981119
GO:0007569cell aging1.50e-021.00e+006.0541221
GO:2000379positive regulation of reactive oxygen species metabolic process1.50e-021.00e+006.0541121
GO:0019894kinesin binding1.50e-021.00e+006.0541121
GO:0001895retina homeostasis1.57e-021.00e+005.9871122
GO:0051084'de novo' posttranslational protein folding1.57e-021.00e+005.9871222
GO:0001836release of cytochrome c from mitochondria1.57e-021.00e+005.9871122
GO:0051262protein tetramerization1.64e-021.00e+005.9221223
GO:0016604nuclear body1.64e-021.00e+005.9221123
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway1.71e-021.00e+005.8611124
GO:0001046core promoter sequence-specific DNA binding1.71e-021.00e+005.8611124
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator1.71e-021.00e+005.8611124
GO:0071479cellular response to ionizing radiation1.71e-021.00e+005.8611124
GO:0046677response to antibiotic1.71e-021.00e+005.8611124
GO:0003730mRNA 3'-UTR binding1.78e-021.00e+005.8021225
GO:0005737cytoplasm1.80e-021.00e+001.4055502633
GO:0070062extracellular vesicular exosome1.81e-021.00e+001.7664431641
GO:0034613cellular protein localization1.85e-021.00e+005.7461126
GO:0030971receptor tyrosine kinase binding1.85e-021.00e+005.7461126
GO:0033077T cell differentiation in thymus1.85e-021.00e+005.7461226
GO:0010332response to gamma radiation1.85e-021.00e+005.7461126
GO:0001756somitogenesis1.92e-021.00e+005.6911127
GO:0034644cellular response to UV1.99e-021.00e+005.6391228
GO:0034332adherens junction organization1.99e-021.00e+005.6391128
GO:2001244positive regulation of intrinsic apoptotic signaling pathway1.99e-021.00e+005.6391128
GO:0005507copper ion binding2.06e-021.00e+005.5881129
GO:0070527platelet aggregation2.06e-021.00e+005.5881129
GO:0051402neuron apoptotic process2.13e-021.00e+005.5391230
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.13e-021.00e+005.5391130
GO:0008104protein localization2.20e-021.00e+005.4921231
GO:0001085RNA polymerase II transcription factor binding2.20e-021.00e+005.4921131
GO:0007596blood coagulation2.25e-021.00e+003.04124339
GO:0006284base-excision repair2.27e-021.00e+005.4461832
GO:0021762substantia nigra development2.41e-021.00e+005.3591134
GO:0044267cellular protein metabolic process2.41e-021.00e+002.98725352
GO:0042802identical protein binding2.44e-021.00e+002.97827354
GO:0048146positive regulation of fibroblast proliferation2.48e-021.00e+005.3171135
GO:0005515protein binding2.53e-021.00e+001.0216764124
GO:0022625cytosolic large ribosomal subunit2.55e-021.00e+005.2761236
GO:0035690cellular response to drug2.69e-021.00e+005.1981238
GO:0048511rhythmic process2.69e-021.00e+005.1981138
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding2.83e-021.00e+005.1241240
GO:0043525positive regulation of neuron apoptotic process2.90e-021.00e+005.0881141
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity2.90e-021.00e+005.0881241
GO:0003684damaged DNA binding2.90e-021.00e+005.0881941
GO:0031100organ regeneration3.11e-021.00e+004.9871244
GO:0045216cell-cell junction organization3.11e-021.00e+004.9871144
GO:0051087chaperone binding3.18e-021.00e+004.9541345
GO:0002039p53 binding3.18e-021.00e+004.9541245
GO:0019903protein phosphatase binding3.32e-021.00e+004.8911347
GO:0097193intrinsic apoptotic signaling pathway3.46e-021.00e+004.8311149
GO:0016032viral process3.48e-021.00e+002.705232428
GO:0002020protease binding3.53e-021.00e+004.8021150
GO:0006302double-strand break repair3.67e-021.00e+004.7461852
GO:0006289nucleotide-excision repair3.74e-021.00e+004.7181953
GO:0034329cell junction assembly3.74e-021.00e+004.7181153
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway3.74e-021.00e+004.7181153
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest3.74e-021.00e+004.71811753
GO:0035264multicellular organism growth3.81e-021.00e+004.6911154
GO:0005681spliceosomal complex3.88e-021.00e+004.6651255
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation3.95e-021.00e+004.6391156
GO:0032355response to estradiol4.02e-021.00e+004.6131157
GO:0000785chromatin4.15e-021.00e+004.5631559
GO:0005179hormone activity4.22e-021.00e+004.5391160
GO:0071013catalytic step 2 spliceosome4.29e-021.00e+004.5151561
GO:0019083viral transcription4.29e-021.00e+004.5151261
GO:0006415translational termination4.43e-021.00e+004.4691263
GO:0047485protein N-terminus binding4.57e-021.00e+004.4241265
GO:0006364rRNA processing4.71e-021.00e+004.3801467
GO:0005200structural constituent of cytoskeleton4.78e-021.00e+004.3591268
GO:0006414translational elongation4.84e-021.00e+004.3381269
GO:0006928cellular component movement4.91e-021.00e+004.3171170
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis4.91e-021.00e+004.3171170
GO:0030308negative regulation of cell growth4.91e-021.00e+004.3171270
GO:0006325chromatin organization4.91e-021.00e+004.3171370
GO:0014069postsynaptic density5.12e-021.00e+004.2561173
GO:0016363nuclear matrix5.12e-021.00e+004.2561773
GO:0001649osteoblast differentiation5.19e-021.00e+004.2371274
GO:0010467gene expression5.24e-021.00e+002.383231535
GO:0071456cellular response to hypoxia5.32e-021.00e+004.1981276
GO:0006614SRP-dependent cotranslational protein targeting to membrane5.39e-021.00e+004.1791277
GO:0019058viral life cycle5.46e-021.00e+004.1611378
GO:0016605PML body5.53e-021.00e+004.1421479
GO:0072562blood microparticle5.67e-021.00e+004.1061281
GO:0030529ribonucleoprotein complex5.73e-021.00e+004.0881482
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay5.87e-021.00e+004.0541384
GO:0003700sequence-specific DNA binding transcription factor activity6.10e-021.00e+002.26126582
GO:0044255cellular lipid metabolic process6.21e-021.00e+003.9701289
GO:0006886intracellular protein transport6.21e-021.00e+003.9701289
GO:0006461protein complex assembly6.35e-021.00e+003.9381391
GO:0007050cell cycle arrest6.41e-021.00e+003.9221392
GO:0007219Notch signaling pathway6.62e-021.00e+003.8761495
GO:0000086G2/M transition of mitotic cell cycle6.75e-021.00e+003.8461597
GO:0006457protein folding6.75e-021.00e+003.8461497
GO:0006413translational initiation6.89e-021.00e+003.8171499
GO:0005198structural molecule activity7.02e-021.00e+003.78811101
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.31e-021.00e+002.11528644
GO:0007179transforming growth factor beta receptor signaling pathway7.42e-021.00e+003.70511107
GO:0005615extracellular space7.45e-021.00e+002.10028651
GO:0003735structural constituent of ribosome7.56e-021.00e+003.67812109
GO:0042981regulation of apoptotic process7.76e-021.00e+003.639118112
GO:0006974cellular response to DNA damage stimulus8.36e-021.00e+003.52713121
GO:0006355regulation of transcription, DNA-templated8.79e-021.00e+001.96427715
GO:0030424axon8.83e-021.00e+003.44612128
GO:0000398mRNA splicing, via spliceosome8.83e-021.00e+003.44618128
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription9.09e-021.00e+003.40211132
GO:0031625ubiquitin protein ligase binding9.49e-021.00e+003.33815138
GO:0005759mitochondrial matrix9.55e-021.00e+003.32715139
GO:0044212transcription regulatory region DNA binding9.81e-021.00e+003.28612143
GO:0001701in utero embryonic development1.05e-011.00e+003.17913154
GO:0044822poly(A) RNA binding1.07e-011.00e+001.804225799
GO:0008380RNA splicing1.12e-011.00e+003.08017165
GO:0007067mitotic nuclear division1.12e-011.00e+003.08018165
GO:0016071mRNA metabolic process1.16e-011.00e+003.037121170
GO:0000166nucleotide binding1.20e-011.00e+002.98716176
GO:0006412translation1.21e-011.00e+002.97013178
GO:0016070RNA metabolic process1.27e-011.00e+002.891121188
GO:0005524ATP binding1.29e-011.00e+001.645223892
GO:0005856cytoskeleton1.29e-011.00e+002.87612190
GO:0043065positive regulation of apoptotic process1.36e-011.00e+002.78813202
GO:0030154cell differentiation1.37e-011.00e+002.77413204
GO:0008134transcription factor binding1.41e-011.00e+002.73914209
GO:0019899enzyme binding1.41e-011.00e+002.73214210
GO:0003677DNA binding1.42e-011.00e+001.559218947
GO:0007275multicellular organismal development1.44e-011.00e+002.70514214
GO:0007411axon guidance1.58e-011.00e+002.55711237
GO:0008283cell proliferation1.59e-011.00e+002.54516239
GO:0003682chromatin binding1.67e-011.00e+002.46916252
GO:0005634nucleus1.72e-011.00e+000.7824673246
GO:0046982protein heterodimerization activity1.75e-011.00e+002.39615265
GO:0008285negative regulation of cell proliferation1.82e-011.00e+002.33214277
GO:0005925focal adhesion1.86e-011.00e+002.30614282
GO:0000278mitotic cell cycle2.05e-011.00e+002.151135314
GO:0045892negative regulation of transcription, DNA-templated2.06e-011.00e+002.13817317
GO:0043066negative regulation of apoptotic process2.09e-011.00e+002.115120322
GO:0005730nucleolus2.14e-011.00e+001.1972411217
GO:0006366transcription from RNA polymerase II promoter2.20e-011.00e+002.03216341
GO:0005783endoplasmic reticulum2.43e-011.00e+001.87213381
GO:0006915apoptotic process2.60e-011.00e+001.763121411
GO:0045087innate immune response2.82e-011.00e+001.62617452
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.85e-011.00e+001.61314456
GO:0005739mitochondrion3.87e-011.00e+001.082111659
GO:0008270zinc ion binding4.18e-011.00e+000.94017727
GO:0044281small molecule metabolic process4.69e-011.00e+000.725132844