reg-snw-5925

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-5925 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPA2	6118	1	1.250	0.802	7	TF	Yes	-
ACTB	60	2	1.153	0.833	23	-	Yes	-
[ RB1 ]	5925	1	-0.102	0.802	351	TF	-	-
PPCS	79717	1	-0.569	0.802	2	-	-	Yes
OGDH	4967	1	0.847	0.802	13	-	Yes	-
PPIE	10450	1	0.567	0.802	41	TF	-	-
TFRC	7037	1	0.730	0.802	17	-	-	-
PGD	5226	1	1.201	0.802	14	-	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot

Related GO terms (205)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0061034	olfactory bulb mitral cell layer development	8.19e-04	1.00e+00	10.253	1	1	1
GO:0090230	regulation of centromere complex assembly	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004998	transferrin receptor activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0031134	sister chromatid biorientation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0097286	iron ion import	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0019521	D-gluconate metabolic process	8.19e-04	1.00e+00	10.253	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0045252	oxoglutarate dehydrogenase complex	1.64e-03	1.00e+00	9.253	1	1	2
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	1.64e-03	1.00e+00	9.253	1	1	2
GO:0034088	maintenance of mitotic sister chromatid cohesion	1.64e-03	1.00e+00	9.253	1	1	2
GO:0019322	pentose biosynthetic process	1.64e-03	1.00e+00	9.253	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	1.64e-03	1.00e+00	9.253	1	1	2
GO:0016605	PML body	1.75e-03	1.00e+00	4.950	2	4	79
GO:0072562	blood microparticle	1.84e-03	1.00e+00	4.914	2	2	81
GO:0006104	succinyl-CoA metabolic process	2.46e-03	1.00e+00	8.668	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.46e-03	1.00e+00	8.668	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.46e-03	1.00e+00	8.668	1	1	3
GO:2000001	regulation of DNA damage checkpoint	2.46e-03	1.00e+00	8.668	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	2.46e-03	1.00e+00	8.668	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	2.46e-03	1.00e+00	8.668	1	1	3
GO:0030976	thiamine pyrophosphate binding	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006457	protein folding	2.63e-03	1.00e+00	4.653	2	4	97
GO:0071922	regulation of cohesin localization to chromatin	3.27e-03	1.00e+00	8.253	1	1	4
GO:0043550	regulation of lipid kinase activity	3.27e-03	1.00e+00	8.253	1	1	4
GO:0035189	Rb-E2F complex	3.27e-03	1.00e+00	8.253	1	1	4
GO:0034349	glial cell apoptotic process	3.27e-03	1.00e+00	8.253	1	1	4
GO:0021860	pyramidal neuron development	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006554	lysine catabolic process	3.27e-03	1.00e+00	8.253	1	1	4
GO:0009108	coenzyme biosynthetic process	4.09e-03	1.00e+00	7.931	1	1	5
GO:0021695	cerebellar cortex development	4.09e-03	1.00e+00	7.931	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	4.09e-03	1.00e+00	7.931	1	1	5
GO:0030957	Tat protein binding	4.09e-03	1.00e+00	7.931	1	2	5
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000730	DNA recombinase assembly	4.09e-03	1.00e+00	7.931	1	3	5
GO:0006734	NADH metabolic process	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000082	G1/S transition of mitotic cell cycle	4.33e-03	1.00e+00	4.288	2	24	125
GO:0043353	enucleate erythrocyte differentiation	4.91e-03	1.00e+00	7.668	1	1	6
GO:0000075	cell cycle checkpoint	4.91e-03	1.00e+00	7.668	1	2	6
GO:0070688	MLL5-L complex	4.91e-03	1.00e+00	7.668	1	1	6
GO:0016018	cyclosporin A binding	4.91e-03	1.00e+00	7.668	1	1	6
GO:0031625	ubiquitin protein ligase binding	5.25e-03	1.00e+00	4.145	2	5	138
GO:0005662	DNA replication factor A complex	6.54e-03	1.00e+00	7.253	1	3	8
GO:0021756	striatum development	6.54e-03	1.00e+00	7.253	1	1	8
GO:0006098	pentose-phosphate shunt	7.35e-03	1.00e+00	7.083	1	1	9
GO:0097284	hepatocyte apoptotic process	7.35e-03	1.00e+00	7.083	1	1	9
GO:0010569	regulation of double-strand break repair via homologous recombination	7.35e-03	1.00e+00	7.083	1	2	9
GO:0015939	pantothenate metabolic process	7.35e-03	1.00e+00	7.083	1	1	9
GO:0031571	mitotic G1 DNA damage checkpoint	7.35e-03	1.00e+00	7.083	1	2	9
GO:0015937	coenzyme A biosynthetic process	7.35e-03	1.00e+00	7.083	1	1	9
GO:0050998	nitric-oxide synthase binding	8.17e-03	1.00e+00	6.931	1	1	10
GO:0045780	positive regulation of bone resorption	8.17e-03	1.00e+00	6.931	1	1	10
GO:0021794	thalamus development	8.17e-03	1.00e+00	6.931	1	1	10
GO:0042551	neuron maturation	8.17e-03	1.00e+00	6.931	1	1	10
GO:0045651	positive regulation of macrophage differentiation	8.17e-03	1.00e+00	6.931	1	1	10
GO:0006103	2-oxoglutarate metabolic process	8.98e-03	1.00e+00	6.794	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	9.79e-03	1.00e+00	6.668	1	3	12
GO:0051146	striated muscle cell differentiation	9.79e-03	1.00e+00	6.668	1	1	12
GO:0045445	myoblast differentiation	1.06e-02	1.00e+00	6.553	1	2	13
GO:0016514	SWI/SNF complex	1.06e-02	1.00e+00	6.553	1	1	13
GO:0035861	site of double-strand break	1.06e-02	1.00e+00	6.553	1	1	13
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	1.22e-02	1.00e+00	6.347	1	1	15
GO:0045879	negative regulation of smoothened signaling pathway	1.22e-02	1.00e+00	6.347	1	1	15
GO:0030863	cortical cytoskeleton	1.22e-02	1.00e+00	6.347	1	1	15
GO:0045070	positive regulation of viral genome replication	1.30e-02	1.00e+00	6.253	1	1	16
GO:0006298	mismatch repair	1.38e-02	1.00e+00	6.166	1	4	17
GO:0000718	nucleotide-excision repair, DNA damage removal	1.38e-02	1.00e+00	6.166	1	5	17
GO:0033572	transferrin transport	1.47e-02	1.00e+00	6.083	1	1	18
GO:0006297	nucleotide-excision repair, DNA gap filling	1.47e-02	1.00e+00	6.083	1	5	18
GO:0030316	osteoclast differentiation	1.47e-02	1.00e+00	6.083	1	1	18
GO:0048565	digestive tract development	1.55e-02	1.00e+00	6.005	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	1.55e-02	1.00e+00	6.005	1	1	19
GO:0043044	ATP-dependent chromatin remodeling	1.63e-02	1.00e+00	5.931	1	2	20
GO:0006099	tricarboxylic acid cycle	1.63e-02	1.00e+00	5.931	1	1	20
GO:0032201	telomere maintenance via semi-conservative replication	1.63e-02	1.00e+00	5.931	1	7	20
GO:0007346	regulation of mitotic cell cycle	1.71e-02	1.00e+00	5.861	1	2	21
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1.71e-02	1.00e+00	5.861	1	2	21
GO:0019894	kinesin binding	1.71e-02	1.00e+00	5.861	1	1	21
GO:0001895	retina homeostasis	1.79e-02	1.00e+00	5.794	1	1	22
GO:0051084	'de novo' posttranslational protein folding	1.79e-02	1.00e+00	5.794	1	2	22
GO:0000722	telomere maintenance via recombination	1.79e-02	1.00e+00	5.794	1	7	22
GO:0000413	protein peptidyl-prolyl isomerization	1.95e-02	1.00e+00	5.668	1	1	24
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1.95e-02	1.00e+00	5.668	1	1	24
GO:0006096	glycolytic process	2.03e-02	1.00e+00	5.610	1	2	25
GO:0007093	mitotic cell cycle checkpoint	2.03e-02	1.00e+00	5.610	1	1	25
GO:0031492	nucleosomal DNA binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0051219	phosphoprotein binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0050661	NADP binding	2.11e-02	1.00e+00	5.553	1	1	26
GO:0006091	generation of precursor metabolites and energy	2.19e-02	1.00e+00	5.499	1	1	27
GO:0034332	adherens junction organization	2.27e-02	1.00e+00	5.446	1	1	28
GO:0031072	heat shock protein binding	2.27e-02	1.00e+00	5.446	1	2	28
GO:0006271	DNA strand elongation involved in DNA replication	2.35e-02	1.00e+00	5.395	1	8	29
GO:0000781	chromosome, telomeric region	2.35e-02	1.00e+00	5.395	1	2	29
GO:0070527	platelet aggregation	2.35e-02	1.00e+00	5.395	1	1	29
GO:0051402	neuron apoptotic process	2.43e-02	1.00e+00	5.347	1	2	30
GO:0050681	androgen receptor binding	2.43e-02	1.00e+00	5.347	1	2	30
GO:0021766	hippocampus development	2.51e-02	1.00e+00	5.299	1	2	31
GO:0001102	RNA polymerase II activating transcription factor binding	2.51e-02	1.00e+00	5.299	1	2	31
GO:0000278	mitotic cell cycle	2.54e-02	1.00e+00	2.959	2	35	314
GO:0044281	small molecule metabolic process	2.59e-02	1.00e+00	2.117	3	32	844
GO:0006284	base-excision repair	2.59e-02	1.00e+00	5.253	1	8	32
GO:0019900	kinase binding	2.59e-02	1.00e+00	5.253	1	1	32
GO:0035914	skeletal muscle cell differentiation	2.67e-02	1.00e+00	5.209	1	1	33
GO:0021762	substantia nigra development	2.75e-02	1.00e+00	5.166	1	1	34
GO:0030521	androgen receptor signaling pathway	2.83e-02	1.00e+00	5.124	1	2	35
GO:0031966	mitochondrial membrane	2.83e-02	1.00e+00	5.124	1	1	35
GO:0005654	nucleoplasm	2.86e-02	1.00e+00	2.064	3	55	876
GO:0005905	coated pit	2.99e-02	1.00e+00	5.044	1	2	37
GO:0070062	extracellular vesicular exosome	3.15e-02	1.00e+00	1.573	4	43	1641
GO:0050680	negative regulation of epithelial cell proliferation	3.15e-02	1.00e+00	4.968	1	1	39
GO:0042802	identical protein binding	3.17e-02	1.00e+00	2.786	2	7	354
GO:0006283	transcription-coupled nucleotide-excision repair	3.23e-02	1.00e+00	4.931	1	6	40
GO:0006879	cellular iron ion homeostasis	3.23e-02	1.00e+00	4.931	1	1	40
GO:0003684	damaged DNA binding	3.31e-02	1.00e+00	4.896	1	9	41
GO:0001047	core promoter binding	3.39e-02	1.00e+00	4.861	1	2	42
GO:0000724	double-strand break repair via homologous recombination	3.39e-02	1.00e+00	4.861	1	5	42
GO:0055037	recycling endosome	3.47e-02	1.00e+00	4.827	1	1	43
GO:0045216	cell-cell junction organization	3.55e-02	1.00e+00	4.794	1	1	44
GO:0051087	chaperone binding	3.63e-02	1.00e+00	4.762	1	3	45
GO:0003725	double-stranded RNA binding	3.63e-02	1.00e+00	4.762	1	3	45
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	3.63e-02	1.00e+00	4.762	1	2	45
GO:0019903	protein phosphatase binding	3.79e-02	1.00e+00	4.699	1	3	47
GO:0000723	telomere maintenance	3.79e-02	1.00e+00	4.699	1	8	47
GO:0001558	regulation of cell growth	3.95e-02	1.00e+00	4.639	1	2	49
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.95e-02	1.00e+00	4.639	1	3	49
GO:0006767	water-soluble vitamin metabolic process	4.03e-02	1.00e+00	4.610	1	2	50
GO:0006469	negative regulation of protein kinase activity	4.03e-02	1.00e+00	4.610	1	1	50
GO:0006898	receptor-mediated endocytosis	4.18e-02	1.00e+00	4.553	1	1	52
GO:0006302	double-strand break repair	4.18e-02	1.00e+00	4.553	1	8	52
GO:0006289	nucleotide-excision repair	4.26e-02	1.00e+00	4.525	1	9	53
GO:0034329	cell junction assembly	4.26e-02	1.00e+00	4.525	1	1	53
GO:0006766	vitamin metabolic process	4.26e-02	1.00e+00	4.525	1	2	53
GO:0006338	chromatin remodeling	4.42e-02	1.00e+00	4.472	1	2	55
GO:0031175	neuron projection development	4.42e-02	1.00e+00	4.472	1	1	55
GO:0016032	viral process	4.50e-02	1.00e+00	2.512	2	32	428
GO:0003697	single-stranded DNA binding	4.58e-02	1.00e+00	4.421	1	6	57
GO:0000785	chromatin	4.73e-02	1.00e+00	4.371	1	5	59
GO:0007265	Ras protein signal transduction	4.73e-02	1.00e+00	4.371	1	3	59
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	5	61
GO:0016023	cytoplasmic membrane-bounded vesicle	5.05e-02	1.00e+00	4.276	1	1	63
GO:0042470	melanosome	5.13e-02	1.00e+00	4.253	1	2	64
GO:0047485	protein N-terminus binding	5.20e-02	1.00e+00	4.231	1	2	65
GO:0005200	structural constituent of cytoskeleton	5.44e-02	1.00e+00	4.166	1	2	68
GO:0006928	cellular component movement	5.59e-02	1.00e+00	4.124	1	1	70
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.59e-02	1.00e+00	4.124	1	1	70
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.124	1	3	70
GO:0014069	postsynaptic density	5.83e-02	1.00e+00	4.064	1	1	73
GO:0044237	cellular metabolic process	5.98e-02	1.00e+00	4.025	1	1	75
GO:0042127	regulation of cell proliferation	6.37e-02	1.00e+00	3.931	1	3	80
GO:0005819	spindle	6.37e-02	1.00e+00	3.931	1	4	80
GO:0030529	ribonucleoprotein complex	6.53e-02	1.00e+00	3.896	1	4	82
GO:0031982	vesicle	6.91e-02	1.00e+00	3.810	1	1	87
GO:0061024	membrane organization	7.07e-02	1.00e+00	3.778	1	2	89
GO:0007050	cell cycle arrest	7.30e-02	1.00e+00	3.730	1	3	92
GO:0006260	DNA replication	7.45e-02	1.00e+00	3.699	1	11	94
GO:0005768	endosome	7.75e-02	1.00e+00	3.639	1	1	98
GO:0034641	cellular nitrogen compound metabolic process	8.29e-02	1.00e+00	3.539	1	18	105
GO:0000790	nuclear chromatin	8.59e-02	1.00e+00	3.485	1	3	109
GO:0005615	extracellular space	9.51e-02	1.00e+00	1.907	2	8	651
GO:0030424	axon	1.00e-01	1.00e+00	3.253	1	2	128
GO:0000398	mRNA splicing, via spliceosome	1.00e-01	1.00e+00	3.253	1	8	128
GO:0009897	external side of plasma membrane	1.02e-01	1.00e+00	3.220	1	1	131
GO:0005759	mitochondrial matrix	1.08e-01	1.00e+00	3.134	1	5	139
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.11e-01	1.00e+00	3.104	1	2	142
GO:0044822	poly(A) RNA binding	1.35e-01	1.00e+00	1.611	2	25	799
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	6	176
GO:0003713	transcription coactivator activity	1.41e-01	1.00e+00	2.730	1	5	184
GO:0005975	carbohydrate metabolic process	1.43e-01	1.00e+00	2.714	1	2	186
GO:0005856	cytoskeleton	1.46e-01	1.00e+00	2.684	1	2	190
GO:0006281	DNA repair	1.55e-01	1.00e+00	2.588	1	19	203
GO:0008134	transcription factor binding	1.59e-01	1.00e+00	2.546	1	4	209
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	8	210
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.539	1	4	210
GO:0043231	intracellular membrane-bounded organelle	1.65e-01	1.00e+00	2.485	1	7	218
GO:0005829	cytosol	1.67e-01	1.00e+00	1.035	3	58	1787
GO:0019901	protein kinase binding	1.75e-01	1.00e+00	2.395	1	11	232
GO:0007411	axon guidance	1.79e-01	1.00e+00	2.365	1	1	237
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	11	247
GO:0005925	focal adhesion	2.09e-01	1.00e+00	2.114	1	4	282
GO:0005515	protein binding	2.10e-01	1.00e+00	0.566	5	76	4124
GO:0009986	cell surface	2.15e-01	1.00e+00	2.069	1	2	291
GO:0055114	oxidation-reduction process	2.26e-01	1.00e+00	1.987	1	3	308
GO:0045892	negative regulation of transcription, DNA-templated	2.32e-01	1.00e+00	1.945	1	7	317
GO:0055085	transmembrane transport	2.40e-01	1.00e+00	1.891	1	1	329
GO:0007596	blood coagulation	2.46e-01	1.00e+00	1.848	1	4	339
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	5	344
GO:0044267	cellular protein metabolic process	2.55e-01	1.00e+00	1.794	1	5	352
GO:0005634	nucleus	2.57e-01	1.00e+00	0.589	4	67	3246
GO:0016020	membrane	2.59e-01	1.00e+00	1.016	2	38	1207
GO:0045893	positive regulation of transcription, DNA-templated	2.70e-01	1.00e+00	1.695	1	10	377
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.433	1	7	452
GO:0005887	integral component of plasma membrane	3.85e-01	1.00e+00	1.086	1	2	575
GO:0003700	sequence-specific DNA binding transcription factor activity	3.88e-01	1.00e+00	1.069	1	6	582
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.21e-01	1.00e+00	0.922	1	8	644
GO:0005739	mitochondrion	4.28e-01	1.00e+00	0.889	1	11	659
GO:0005576	extracellular region	4.30e-01	1.00e+00	0.881	1	5	663
GO:0006355	regulation of transcription, DNA-templated	4.56e-01	1.00e+00	0.772	1	7	715
GO:0005524	ATP binding	5.35e-01	1.00e+00	0.453	1	23	892
GO:0046872	metal ion binding	5.53e-01	1.00e+00	0.386	1	10	934
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	18	947
GO:0006351	transcription, DNA-templated	6.07e-01	1.00e+00	0.182	1	9	1076
GO:0005730	nucleolus	6.55e-01	1.00e+00	0.004	1	41	1217
GO:0005886	plasma membrane	8.01e-01	1.00e+00	-0.547	1	11	1784
GO:0005737	cytoplasm	9.19e-01	1.00e+00	-1.109	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-5925

Statistics

Genes (8)

Interactions (7)

Related GO terms (205)