meta-int-snw-7167

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-4800	wolf-screen-ratio-mammosphere-adherent	0.833	7.78e-07	2.65e-03	5.08e-03	7	5
int-snw-7167	wolf-screen-ratio-mammosphere-adherent	0.925	3.78e-15	3.03e-03	4.63e-02	16	16

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-7167 subnetwork

Genes (20)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA3	5684	90	0.533	0.815	238	Yes	-
COPA	1314	7	0.434	0.833	170	Yes	-
PSMA2	5683	112	1.093	1.106	108	Yes	-
PSMC3	5702	51	0.719	1.002	276	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
TP53	7157	23	0.432	0.833	665	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
RSL24D1	51187	38	1.300	1.020	59	Yes	-
PCNA	5111	33	0.553	0.974	294	Yes	-
NFYA	4800	7	0.198	0.833	80	-	-
CCNA2	890	54	0.550	0.973	246	Yes	-
EEF2	1938	64	0.890	1.043	301	Yes	-
RPL14	9045	49	1.250	1.113	166	Yes	-
HNRNPK	3190	11	0.488	0.938	252	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
TPI1	7167	2	-0.128	0.925	52	-	Yes
POLR2B	5431	12	0.587	0.940	146	Yes	-
CFL1	1072	18	0.674	1.020	203	Yes	-

Interactions (53)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPC	3183	PSMA3	5684	pp	--	int.I2D: BioGrid
EEF2	1938	PGD	5226	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PSMC3	5702	pp	--	int.I2D: YeastLow, BioGrid_Yeast
POLR2B	5431	PSMC3	5702	pp	--	int.I2D: YeastLow
CFL1	1072	TPI1	7167	pp	--	int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vivo
ACTB	60	NFYA	4800	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PSMC3	5702	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	EEF2	1938	pp	--	int.I2D: YeastLow, IntAct_Yeast
PSMD11	5717	TP53	7157	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
CFL1	1072	TP53	7157	pd	<	reg.ITFP.txt: no annot
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ACTB	60	PSMA3	5684	pp	--	int.I2D: BioGrid, BioGrid_Yeast
EEF2	1938	TP53	7157	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
RPSA	3921	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast
POLR2B	5431	TPI1	7167	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PSMA3	5684	pp	--	int.I2D: BioGrid
ACTB	60	CFL1	1072	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, MINT_Yeast, MIPS, BioGrid, BIND_Yeast, HPRD, IntAct, IntAct_Yeast, MINT, VidalHuman_core, YeastLow, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
EEF2	1938	TPI1	7167	pp	--	int.I2D: YeastLow
PSMC3	5702	TP53	7157	pp	--	int.I2D: BioGrid
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast, YeastLow
EEF2	1938	POLR2B	5431	pp	--	int.I2D: BioGrid_Yeast, YeastLow
HNRNPC	3183	TP53	7157	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PCNA	5111	TP53	7157	pd	<	reg.TRANSFAC.txt: no annot
ACTB	60	HNRNPK	3190	pp	--	int.I2D: IntAct_Rat
CFL1	1072	PGD	5226	pp	--	int.I2D: YeastLow
HNRNPK	3190	RPSA	3921	pp	--	int.I2D: IntAct_Rat
HNRNPK	3190	TP53	7157	pp	--	int.I2D: MINT; int.Mint: MI:0915(physical association)
COPA	1314	RPL14	9045	pd	>	reg.ITFP.txt: no annot
NFYA	4800	TP53	7157	pd	>	reg.pazar.txt: no annot
NFYA	4800	TP53	7157	pp	--	int.Intact: MI:0914(association), MI:0915(physical association), MI:0403(colocalization); int.I2D: BioGrid, HPRD, IntAct, BCI; int.Ravasi: -; int.HPRD: in vivo
HNRNPK	3190	TPI1	7167	pp	--	int.I2D: IntAct_Rat
CCNA2	890	TP53	7157	pp	--	int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro
ACTB	60	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast
PSMC3	5702	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
PSMA3	5684	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast, BioGrid, YeastLow
RPSA	3921	PCNA	5111	pp	--	int.I2D: MINT, BioGrid; int.Mint: MI:0915(physical association)
CFL1	1072	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast
CCNA2	890	NFYA	4800	pd	<	reg.TRANSFAC.txt: no annot
CFL1	1072	COPA	1314	pd	<	reg.ITFP.txt: no annot
PSMA3	5684	TPI1	7167	pp	--	int.I2D: BioGrid
COPA	1314	PSMA3	5684	pp	--	int.I2D: YeastLow
CFL1	1072	RSL24D1	51187	pp	--	int.I2D: YeastLow
PSMA3	5684	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PCNA	5111	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast
CCNA2	890	PCNA	5111	pp	--	int.I2D: BioGrid
PCNA	5111	TPI1	7167	pp	--	int.I2D: BioGrid, MINT; int.Mint: MI:0407(direct interaction), MI:0915(physical association)
PSMC3	5702	TPI1	7167	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMA3	5684	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid
COPA	1314	NFYA	4800	pd	>	reg.ITFP.txt: no annot

Related GO terms (356)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	5.97e-10	9.75e-06	3.161	12	83	1095
GO:0010467	gene expression	1.60e-09	2.60e-05	3.609	10	58	669
GO:0016032	viral process	5.40e-09	8.81e-05	3.766	9	55	540
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.27e-08	2.07e-04	5.972	5	22	65
GO:0070062	extracellular vesicular exosome	6.38e-08	1.04e-03	2.183	14	98	2516
GO:0016071	mRNA metabolic process	2.01e-07	3.28e-03	4.457	6	34	223
GO:0006521	regulation of cellular amino acid metabolic process	3.64e-07	5.94e-03	6.029	4	21	50
GO:0016070	RNA metabolic process	3.67e-07	5.99e-03	4.309	6	34	247
GO:0000502	proteasome complex	6.67e-07	1.09e-02	5.815	4	22	58
GO:0000082	G1/S transition of mitotic cell cycle	8.51e-07	1.39e-02	4.766	5	33	150
GO:0042981	regulation of apoptotic process	8.79e-07	1.44e-02	4.756	5	26	151
GO:0005829	cytosol	8.88e-07	1.45e-02	2.050	13	125	2562
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.06e-06	1.73e-02	5.650	4	24	65
GO:0016020	membrane	1.37e-06	2.23e-02	2.362	11	80	1746
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.43e-06	2.33e-02	5.543	4	24	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.69e-06	2.76e-02	5.483	4	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.79e-06	2.91e-02	5.463	4	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.09e-06	3.42e-02	5.406	4	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.32e-06	3.79e-02	5.369	4	25	79
GO:0005634	nucleus	4.47e-06	7.29e-02	1.435	16	131	4828
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.66e-06	7.60e-02	5.118	4	23	94
GO:0000278	mitotic cell cycle	5.87e-06	9.59e-02	3.621	6	52	398
GO:0043066	negative regulation of apoptotic process	9.52e-06	1.55e-01	3.499	6	30	433
GO:0000209	protein polyubiquitination	1.07e-05	1.75e-01	4.815	4	21	116
GO:0005515	protein binding	1.78e-05	2.90e-01	1.179	17	172	6127
GO:0000790	nuclear chromatin	1.85e-05	3.01e-01	4.617	4	7	133
GO:0019773	proteasome core complex, alpha-subunit complex	3.98e-05	6.49e-01	7.673	2	5	8
GO:0034641	cellular nitrogen compound metabolic process	5.66e-05	9.23e-01	4.205	4	25	177
GO:0006098	pentose-phosphate shunt	7.79e-05	1.00e+00	7.213	2	3	11
GO:0006289	nucleotide-excision repair	7.83e-05	1.00e+00	5.149	3	12	69
GO:0006414	translational elongation	1.90e-04	1.00e+00	4.718	3	11	93
GO:0022624	proteasome accessory complex	1.92e-04	1.00e+00	6.585	2	9	17
GO:0005839	proteasome core complex	2.16e-04	1.00e+00	6.503	2	11	18
GO:0004298	threonine-type endopeptidase activity	2.67e-04	1.00e+00	6.351	2	11	20
GO:0043044	ATP-dependent chromatin remodeling	3.55e-04	1.00e+00	6.149	2	4	23
GO:0006915	apoptotic process	5.16e-04	1.00e+00	2.837	5	34	571
GO:0031492	nucleosomal DNA binding	5.29e-04	1.00e+00	5.865	2	4	28
GO:0019901	protein kinase binding	5.48e-04	1.00e+00	3.351	4	21	320
GO:0044281	small molecule metabolic process	6.00e-04	1.00e+00	2.141	7	57	1295
GO:0030971	receptor tyrosine kinase binding	7.36e-04	1.00e+00	5.628	2	2	33
GO:0000398	mRNA splicing, via spliceosome	1.02e-03	1.00e+00	3.891	3	12	165
GO:0006284	base-excision repair	1.03e-03	1.00e+00	5.387	2	7	39
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.07e-03	1.00e+00	3.865	3	5	168
GO:0032077	positive regulation of deoxyribonuclease activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0043626	PCNA complex	1.23e-03	1.00e+00	9.673	1	1	1
GO:0004807	triose-phosphate isomerase activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0019521	D-gluconate metabolic process	1.23e-03	1.00e+00	9.673	1	1	1
GO:0019682	glyceraldehyde-3-phosphate metabolic process	1.23e-03	1.00e+00	9.673	1	1	1
GO:0044822	poly(A) RNA binding	1.42e-03	1.00e+00	2.183	6	50	1078
GO:0006283	transcription-coupled nucleotide-excision repair	1.43e-03	1.00e+00	5.149	2	8	46
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.97e-03	1.00e+00	4.918	2	5	54
GO:0000932	cytoplasmic mRNA processing body	2.11e-03	1.00e+00	4.865	2	3	56
GO:0030337	DNA polymerase processivity factor activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0097252	oligodendrocyte apoptotic process	2.45e-03	1.00e+00	8.673	1	1	2
GO:0006272	leading strand elongation	2.45e-03	1.00e+00	8.673	1	2	2
GO:1901525	negative regulation of macromitophagy	2.45e-03	1.00e+00	8.673	1	1	2
GO:0006407	rRNA export from nucleus	2.45e-03	1.00e+00	8.673	1	1	2
GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	2.45e-03	1.00e+00	8.673	1	1	2
GO:0070557	PCNA-p21 complex	2.45e-03	1.00e+00	8.673	1	1	2
GO:0090343	positive regulation of cell aging	2.45e-03	1.00e+00	8.673	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.45e-03	1.00e+00	8.673	1	1	2
GO:0019322	pentose biosynthetic process	2.45e-03	1.00e+00	8.673	1	1	2
GO:0005055	laminin receptor activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0008380	RNA splicing	2.70e-03	1.00e+00	3.399	3	13	232
GO:0044267	cellular protein metabolic process	2.75e-03	1.00e+00	2.721	4	24	495
GO:0006412	translation	2.80e-03	1.00e+00	3.381	3	15	235
GO:0010988	regulation of low-density lipoprotein particle clearance	3.67e-03	1.00e+00	8.088	1	1	3
GO:0032139	dinucleotide insertion or deletion binding	3.67e-03	1.00e+00	8.088	1	1	3
GO:0035794	positive regulation of mitochondrial membrane permeability	3.67e-03	1.00e+00	8.088	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.67e-03	1.00e+00	8.088	1	1	3
GO:0051097	negative regulation of helicase activity	3.67e-03	1.00e+00	8.088	1	1	3
GO:0035033	histone deacetylase regulator activity	3.67e-03	1.00e+00	8.088	1	1	3
GO:0002360	T cell lineage commitment	3.67e-03	1.00e+00	8.088	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.67e-03	1.00e+00	8.088	1	1	3
GO:0034103	regulation of tissue remodeling	3.67e-03	1.00e+00	8.088	1	1	3
GO:0007265	Ras protein signal transduction	3.75e-03	1.00e+00	4.444	2	3	75
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.95e-03	1.00e+00	4.406	2	5	77
GO:0071013	catalytic step 2 spliceosome	4.15e-03	1.00e+00	4.369	2	7	79
GO:0019083	viral transcription	4.36e-03	1.00e+00	4.333	2	8	81
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.89e-03	1.00e+00	7.673	1	1	4
GO:0030686	90S preribosome	4.89e-03	1.00e+00	7.673	1	1	4
GO:0032549	ribonucleoside binding	4.89e-03	1.00e+00	7.673	1	2	4
GO:0090403	oxidative stress-induced premature senescence	4.89e-03	1.00e+00	7.673	1	1	4
GO:0001842	neural fold formation	4.89e-03	1.00e+00	7.673	1	1	4
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	4.89e-03	1.00e+00	7.673	1	1	4
GO:0002326	B cell lineage commitment	4.89e-03	1.00e+00	7.673	1	1	4
GO:0016602	CCAAT-binding factor complex	4.89e-03	1.00e+00	7.673	1	1	4
GO:0006415	translational termination	5.01e-03	1.00e+00	4.230	2	8	87
GO:0043234	protein complex	5.56e-03	1.00e+00	3.029	3	17	300
GO:0016363	nuclear matrix	5.59e-03	1.00e+00	4.149	2	11	92
GO:0001940	male pronucleus	6.11e-03	1.00e+00	7.351	1	1	5
GO:0097371	MDM2/MDM4 family protein binding	6.11e-03	1.00e+00	7.351	1	1	5
GO:0043248	proteasome assembly	6.11e-03	1.00e+00	7.351	1	1	5
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.09e-03	1.00e+00	3.972	2	8	104
GO:0005663	DNA replication factor C complex	7.33e-03	1.00e+00	7.088	1	1	6
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	7.33e-03	1.00e+00	7.088	1	1	6
GO:0001221	transcription cofactor binding	7.33e-03	1.00e+00	7.088	1	1	6
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	7.33e-03	1.00e+00	7.088	1	1	6
GO:0002309	T cell proliferation involved in immune response	7.33e-03	1.00e+00	7.088	1	1	6
GO:0033993	response to lipid	7.33e-03	1.00e+00	7.088	1	2	6
GO:0030957	Tat protein binding	7.33e-03	1.00e+00	7.088	1	4	6
GO:0070245	positive regulation of thymocyte apoptotic process	7.33e-03	1.00e+00	7.088	1	1	6
GO:0007406	negative regulation of neuroblast proliferation	7.33e-03	1.00e+00	7.088	1	1	6
GO:0032405	MutLalpha complex binding	7.33e-03	1.00e+00	7.088	1	2	6
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.46e-03	1.00e+00	3.840	2	10	114
GO:0030529	ribonucleoprotein complex	8.46e-03	1.00e+00	3.840	2	8	114
GO:0000028	ribosomal small subunit assembly	8.55e-03	1.00e+00	6.865	1	1	7
GO:0001939	female pronucleus	8.55e-03	1.00e+00	6.865	1	1	7
GO:0030157	pancreatic juice secretion	8.55e-03	1.00e+00	6.865	1	1	7
GO:0031497	chromatin assembly	8.55e-03	1.00e+00	6.865	1	1	7
GO:0030836	positive regulation of actin filament depolymerization	8.55e-03	1.00e+00	6.865	1	2	7
GO:0019058	viral life cycle	8.61e-03	1.00e+00	3.827	2	10	115
GO:0003723	RNA binding	8.84e-03	1.00e+00	2.786	3	19	355
GO:0000733	DNA strand renaturation	9.76e-03	1.00e+00	6.673	1	1	8
GO:0070688	MLL5-L complex	9.76e-03	1.00e+00	6.673	1	1	8
GO:0070182	DNA polymerase binding	9.76e-03	1.00e+00	6.673	1	2	8
GO:0043596	nuclear replication fork	9.76e-03	1.00e+00	6.673	1	1	8
GO:0030042	actin filament depolymerization	9.76e-03	1.00e+00	6.673	1	2	8
GO:0005925	focal adhesion	9.89e-03	1.00e+00	2.726	3	18	370
GO:0008494	translation activator activity	1.10e-02	1.00e+00	6.503	1	1	9
GO:0010389	regulation of G2/M transition of mitotic cell cycle	1.10e-02	1.00e+00	6.503	1	1	9
GO:0006983	ER overload response	1.10e-02	1.00e+00	6.503	1	2	9
GO:0031065	positive regulation of histone deacetylation	1.10e-02	1.00e+00	6.503	1	1	9
GO:0006413	translational initiation	1.11e-02	1.00e+00	3.639	2	12	131
GO:0009615	response to virus	1.12e-02	1.00e+00	3.628	2	6	132
GO:0005737	cytoplasm	1.15e-02	1.00e+00	1.037	10	98	3976
GO:0090399	replicative senescence	1.22e-02	1.00e+00	6.351	1	1	10
GO:2000648	positive regulation of stem cell proliferation	1.22e-02	1.00e+00	6.351	1	1	10
GO:0046902	regulation of mitochondrial membrane permeability	1.22e-02	1.00e+00	6.351	1	1	10
GO:0003735	structural constituent of ribosome	1.27e-02	1.00e+00	3.533	2	8	141
GO:0005730	nucleolus	1.30e-02	1.00e+00	1.540	6	70	1684
GO:0008340	determination of adult lifespan	1.34e-02	1.00e+00	6.213	1	1	11
GO:0071850	mitotic cell cycle arrest	1.34e-02	1.00e+00	6.213	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.34e-02	1.00e+00	6.213	1	3	11
GO:0061001	regulation of dendritic spine morphogenesis	1.34e-02	1.00e+00	6.213	1	2	11
GO:0045120	pronucleus	1.34e-02	1.00e+00	6.213	1	1	11
GO:0033762	response to glucagon	1.34e-02	1.00e+00	6.213	1	1	11
GO:2000036	regulation of stem cell maintenance	1.34e-02	1.00e+00	6.213	1	2	11
GO:0061024	membrane organization	1.36e-02	1.00e+00	3.483	2	5	146
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.45e-02	1.00e+00	3.434	2	2	151
GO:0019985	translesion synthesis	1.46e-02	1.00e+00	6.088	1	2	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.46e-02	1.00e+00	6.088	1	2	12
GO:0006275	regulation of DNA replication	1.46e-02	1.00e+00	6.088	1	2	12
GO:0070266	necroptotic process	1.46e-02	1.00e+00	6.088	1	1	12
GO:0032461	positive regulation of protein oligomerization	1.46e-02	1.00e+00	6.088	1	1	12
GO:0009303	rRNA transcription	1.46e-02	1.00e+00	6.088	1	1	12
GO:0005838	proteasome regulatory particle	1.46e-02	1.00e+00	6.088	1	7	12
GO:0042273	ribosomal large subunit biogenesis	1.58e-02	1.00e+00	5.972	1	4	13
GO:0048205	COPI coating of Golgi vesicle	1.58e-02	1.00e+00	5.972	1	1	13
GO:0048260	positive regulation of receptor-mediated endocytosis	1.58e-02	1.00e+00	5.972	1	1	13
GO:0030126	COPI vesicle coat	1.58e-02	1.00e+00	5.972	1	1	13
GO:0008266	poly(U) RNA binding	1.58e-02	1.00e+00	5.972	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.70e-02	1.00e+00	5.865	1	4	14
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	1.70e-02	1.00e+00	5.865	1	2	14
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.70e-02	1.00e+00	5.865	1	1	14
GO:0030330	DNA damage response, signal transduction by p53 class mediator	1.70e-02	1.00e+00	5.865	1	1	14
GO:0007095	mitotic G2 DNA damage checkpoint	1.70e-02	1.00e+00	5.865	1	1	14
GO:0009651	response to salt stress	1.70e-02	1.00e+00	5.865	1	2	14
GO:0048568	embryonic organ development	1.70e-02	1.00e+00	5.865	1	1	14
GO:0007596	blood coagulation	1.82e-02	1.00e+00	2.399	3	14	464
GO:0005665	DNA-directed RNA polymerase II, core complex	1.94e-02	1.00e+00	5.673	1	4	16
GO:0050998	nitric-oxide synthase binding	1.94e-02	1.00e+00	5.673	1	1	16
GO:0042149	cellular response to glucose starvation	2.06e-02	1.00e+00	5.585	1	1	17
GO:0003746	translation elongation factor activity	2.06e-02	1.00e+00	5.585	1	3	17
GO:0031258	lamellipodium membrane	2.06e-02	1.00e+00	5.585	1	2	17
GO:0045893	positive regulation of transcription, DNA-templated	2.06e-02	1.00e+00	2.330	3	17	487
GO:0002102	podosome	2.06e-02	1.00e+00	5.585	1	2	17
GO:0022604	regulation of cell morphogenesis	2.06e-02	1.00e+00	5.585	1	1	17
GO:0042802	identical protein binding	2.11e-02	1.00e+00	2.318	3	18	491
GO:0051721	protein phosphatase 2A binding	2.18e-02	1.00e+00	5.503	1	1	18
GO:0005657	replication fork	2.18e-02	1.00e+00	5.503	1	3	18
GO:0048863	stem cell differentiation	2.30e-02	1.00e+00	5.425	1	1	19
GO:0035035	histone acetyltransferase binding	2.30e-02	1.00e+00	5.425	1	1	19
GO:0071158	positive regulation of cell cycle arrest	2.30e-02	1.00e+00	5.425	1	1	19
GO:1903506	regulation of nucleic acid-templated transcription	2.30e-02	1.00e+00	5.425	1	1	19
GO:0010165	response to X-ray	2.30e-02	1.00e+00	5.425	1	2	19
GO:0002931	response to ischemia	2.42e-02	1.00e+00	5.351	1	1	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	2.42e-02	1.00e+00	5.351	1	1	20
GO:0006298	mismatch repair	2.42e-02	1.00e+00	5.351	1	6	20
GO:0008156	negative regulation of DNA replication	2.54e-02	1.00e+00	5.280	1	1	21
GO:0007369	gastrulation	2.54e-02	1.00e+00	5.280	1	1	21
GO:0030010	establishment of cell polarity	2.54e-02	1.00e+00	5.280	1	2	21
GO:0000281	mitotic cytokinesis	2.54e-02	1.00e+00	5.280	1	2	21
GO:0005669	transcription factor TFIID complex	2.66e-02	1.00e+00	5.213	1	1	22
GO:0090200	positive regulation of release of cytochrome c from mitochondria	2.66e-02	1.00e+00	5.213	1	1	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.66e-02	1.00e+00	5.213	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.66e-02	1.00e+00	5.213	1	3	22
GO:0046686	response to cadmium ion	2.66e-02	1.00e+00	5.213	1	3	22
GO:0032201	telomere maintenance via semi-conservative replication	2.66e-02	1.00e+00	5.213	1	7	22
GO:0030863	cortical cytoskeleton	2.66e-02	1.00e+00	5.213	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.66e-02	1.00e+00	5.213	1	4	22
GO:0043236	laminin binding	2.78e-02	1.00e+00	5.149	1	1	23
GO:0043200	response to amino acid	2.78e-02	1.00e+00	5.149	1	1	23
GO:0001836	release of cytochrome c from mitochondria	2.90e-02	1.00e+00	5.088	1	2	24
GO:0048147	negative regulation of fibroblast proliferation	2.90e-02	1.00e+00	5.088	1	1	24
GO:0000060	protein import into nucleus, translocation	2.90e-02	1.00e+00	5.088	1	4	24
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.90e-02	1.00e+00	5.088	1	1	24
GO:0030864	cortical actin cytoskeleton	3.02e-02	1.00e+00	5.029	1	1	25
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.02e-02	1.00e+00	5.029	1	1	25
GO:0003899	DNA-directed RNA polymerase activity	3.02e-02	1.00e+00	5.029	1	2	25
GO:0007569	cell aging	3.02e-02	1.00e+00	5.029	1	2	25
GO:0005844	polysome	3.02e-02	1.00e+00	5.029	1	4	25
GO:0071479	cellular response to ionizing radiation	3.02e-02	1.00e+00	5.029	1	1	25
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	3.14e-02	1.00e+00	4.972	1	3	26
GO:0000722	telomere maintenance via recombination	3.14e-02	1.00e+00	4.972	1	7	26
GO:0005615	extracellular space	3.19e-02	1.00e+00	1.692	4	17	1010
GO:0001046	core promoter sequence-specific DNA binding	3.38e-02	1.00e+00	4.865	1	1	28
GO:0043022	ribosome binding	3.38e-02	1.00e+00	4.865	1	3	28
GO:0019894	kinesin binding	3.38e-02	1.00e+00	4.865	1	1	28
GO:0010332	response to gamma radiation	3.50e-02	1.00e+00	4.815	1	2	29
GO:0003730	mRNA 3'-UTR binding	3.50e-02	1.00e+00	4.815	1	2	29
GO:0006370	7-methylguanosine mRNA capping	3.61e-02	1.00e+00	4.766	1	4	30
GO:0051262	protein tetramerization	3.61e-02	1.00e+00	4.766	1	3	30
GO:0001755	neural crest cell migration	3.61e-02	1.00e+00	4.766	1	2	30
GO:0042254	ribosome biogenesis	3.61e-02	1.00e+00	4.766	1	1	30
GO:0021549	cerebellum development	3.61e-02	1.00e+00	4.766	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3.61e-02	1.00e+00	4.766	1	2	30
GO:0046677	response to antibiotic	3.73e-02	1.00e+00	4.718	1	2	31
GO:0016604	nuclear body	3.73e-02	1.00e+00	4.718	1	2	31
GO:0006271	DNA strand elongation involved in DNA replication	3.73e-02	1.00e+00	4.718	1	9	31
GO:0050661	NADP binding	3.85e-02	1.00e+00	4.673	1	1	32
GO:0034644	cellular response to UV	3.85e-02	1.00e+00	4.673	1	5	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.85e-02	1.00e+00	4.673	1	2	32
GO:0033077	T cell differentiation in thymus	3.97e-02	1.00e+00	4.628	1	2	33
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	3.97e-02	1.00e+00	4.628	1	1	33
GO:0006281	DNA repair	4.09e-02	1.00e+00	2.628	2	22	264
GO:0001085	RNA polymerase II transcription factor binding	4.09e-02	1.00e+00	4.585	1	2	34
GO:0034332	adherens junction organization	4.32e-02	1.00e+00	4.503	1	1	36
GO:0051402	neuron apoptotic process	4.32e-02	1.00e+00	4.503	1	2	36
GO:0001895	retina homeostasis	4.32e-02	1.00e+00	4.503	1	1	36
GO:0005975	carbohydrate metabolic process	4.37e-02	1.00e+00	2.574	2	5	274
GO:0051084	'de novo' posttranslational protein folding	4.44e-02	1.00e+00	4.463	1	4	37
GO:0001756	somitogenesis	4.56e-02	1.00e+00	4.425	1	1	38
GO:0070527	platelet aggregation	4.56e-02	1.00e+00	4.425	1	2	38
GO:0006096	glycolytic process	4.67e-02	1.00e+00	4.387	1	4	39
GO:0022627	cytosolic small ribosomal subunit	4.67e-02	1.00e+00	4.387	1	3	39
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	4.79e-02	1.00e+00	4.351	1	2	40
GO:0048146	positive regulation of fibroblast proliferation	5.26e-02	1.00e+00	4.213	1	2	44
GO:0034613	cellular protein localization	5.26e-02	1.00e+00	4.213	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5.26e-02	1.00e+00	4.213	1	2	44
GO:0050434	positive regulation of viral transcription	5.26e-02	1.00e+00	4.213	1	5	44
GO:0006094	gluconeogenesis	5.38e-02	1.00e+00	4.181	1	3	45
GO:0021762	substantia nigra development	5.49e-02	1.00e+00	4.149	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	5.49e-02	1.00e+00	4.149	1	2	46
GO:0045727	positive regulation of translation	5.49e-02	1.00e+00	4.149	1	4	46
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	5.61e-02	1.00e+00	4.118	1	3	47
GO:0048511	rhythmic process	5.61e-02	1.00e+00	4.118	1	2	47
GO:0005507	copper ion binding	5.72e-02	1.00e+00	4.088	1	2	48
GO:0007266	Rho protein signal transduction	5.72e-02	1.00e+00	4.088	1	2	48
GO:0022625	cytosolic large ribosomal subunit	5.84e-02	1.00e+00	4.058	1	5	49
GO:0031100	organ regeneration	5.96e-02	1.00e+00	4.029	1	4	50
GO:0035690	cellular response to drug	5.96e-02	1.00e+00	4.029	1	2	50
GO:0007411	axon guidance	6.00e-02	1.00e+00	2.319	2	9	327
GO:0003684	damaged DNA binding	6.07e-02	1.00e+00	4.000	1	11	51
GO:0008283	cell proliferation	6.13e-02	1.00e+00	2.302	2	12	331
GO:0003682	chromatin binding	6.23e-02	1.00e+00	2.289	2	12	334
GO:0097193	intrinsic apoptotic signaling pathway	6.53e-02	1.00e+00	3.891	1	4	55
GO:0002039	p53 binding	6.53e-02	1.00e+00	3.891	1	7	55
GO:0007275	multicellular organismal development	6.56e-02	1.00e+00	2.246	2	5	344
GO:0008104	protein localization	6.65e-02	1.00e+00	3.865	1	3	56
GO:0002244	hematopoietic progenitor cell differentiation	6.88e-02	1.00e+00	3.815	1	1	58
GO:0051087	chaperone binding	6.99e-02	1.00e+00	3.790	1	6	59
GO:0045216	cell-cell junction organization	6.99e-02	1.00e+00	3.790	1	2	59
GO:0000723	telomere maintenance	6.99e-02	1.00e+00	3.790	1	8	59
GO:0006396	RNA processing	7.11e-02	1.00e+00	3.766	1	2	60
GO:0006302	double-strand break repair	7.33e-02	1.00e+00	3.718	1	8	62
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	7.43e-02	1.00e+00	1.594	3	19	811
GO:0019903	protein phosphatase binding	7.45e-02	1.00e+00	3.695	1	4	63
GO:0042995	cell projection	7.45e-02	1.00e+00	3.695	1	6	63
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	7.56e-02	1.00e+00	3.673	1	1	64
GO:0030855	epithelial cell differentiation	7.68e-02	1.00e+00	3.650	1	4	65
GO:0006368	transcription elongation from RNA polymerase II promoter	7.90e-02	1.00e+00	3.606	1	6	67
GO:0003697	single-stranded DNA binding	8.13e-02	1.00e+00	3.564	1	9	69
GO:0035264	multicellular organism growth	8.24e-02	1.00e+00	3.543	1	1	70
GO:0034329	cell junction assembly	8.35e-02	1.00e+00	3.523	1	1	71
GO:0032587	ruffle membrane	8.47e-02	1.00e+00	3.503	1	4	72
GO:0032355	response to estradiol	8.58e-02	1.00e+00	3.483	1	5	73
GO:0000785	chromatin	8.58e-02	1.00e+00	3.483	1	5	73
GO:0002020	protease binding	8.69e-02	1.00e+00	3.463	1	4	74
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	8.81e-02	1.00e+00	3.444	1	1	75
GO:0006366	transcription from RNA polymerase II promoter	9.45e-02	1.00e+00	1.941	2	12	425
GO:0002576	platelet degranulation	9.59e-02	1.00e+00	3.315	1	4	82
GO:0005681	spliceosomal complex	9.70e-02	1.00e+00	3.297	1	3	83
GO:0005179	hormone activity	9.81e-02	1.00e+00	3.280	1	1	84
GO:0047485	protein N-terminus binding	1.00e-01	1.00e+00	3.246	1	4	86
GO:0016605	PML body	1.07e-01	1.00e+00	3.149	1	5	92
GO:0006928	cellular component movement	1.07e-01	1.00e+00	3.149	1	7	92
GO:0005200	structural constituent of cytoskeleton	1.08e-01	1.00e+00	3.133	1	7	93
GO:0001649	osteoblast differentiation	1.10e-01	1.00e+00	3.103	1	6	95
GO:0006364	rRNA processing	1.11e-01	1.00e+00	3.088	1	5	96
GO:0007010	cytoskeleton organization	1.11e-01	1.00e+00	3.088	1	2	96
GO:0071456	cellular response to hypoxia	1.14e-01	1.00e+00	3.058	1	4	98
GO:0014069	postsynaptic density	1.22e-01	1.00e+00	2.945	1	1	106
GO:0006461	protein complex assembly	1.28e-01	1.00e+00	2.878	1	6	111
GO:0030308	negative regulation of cell growth	1.30e-01	1.00e+00	2.852	1	6	113
GO:0072562	blood microparticle	1.33e-01	1.00e+00	2.815	1	4	116
GO:0006006	glucose metabolic process	1.36e-01	1.00e+00	2.778	1	4	119
GO:0006325	chromatin organization	1.40e-01	1.00e+00	2.730	1	4	123
GO:0007219	Notch signaling pathway	1.43e-01	1.00e+00	2.707	1	4	125
GO:0007050	cell cycle arrest	1.44e-01	1.00e+00	2.695	1	7	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.45e-01	1.00e+00	2.684	1	5	127
GO:0030036	actin cytoskeleton organization	1.47e-01	1.00e+00	2.661	1	5	129
GO:0007179	transforming growth factor beta receptor signaling pathway	1.48e-01	1.00e+00	2.650	1	3	130
GO:0031982	vesicle	1.52e-01	1.00e+00	2.606	1	10	134
GO:0000086	G2/M transition of mitotic cell cycle	1.55e-01	1.00e+00	2.574	1	7	137
GO:0044255	cellular lipid metabolic process	1.58e-01	1.00e+00	2.543	1	4	140
GO:0007507	heart development	1.59e-01	1.00e+00	2.533	1	5	141
GO:0005911	cell-cell junction	1.60e-01	1.00e+00	2.523	1	3	142
GO:0016887	ATPase activity	1.63e-01	1.00e+00	2.503	1	7	144
GO:0010628	positive regulation of gene expression	1.68e-01	1.00e+00	2.453	1	4	149
GO:0006457	protein folding	1.68e-01	1.00e+00	2.453	1	8	149
GO:0045087	innate immune response	1.73e-01	1.00e+00	1.406	2	20	616
GO:0006974	cellular response to DNA damage stimulus	1.77e-01	1.00e+00	2.369	1	8	158
GO:0005198	structural molecule activity	1.78e-01	1.00e+00	2.360	1	4	159
GO:0044212	transcription regulatory region DNA binding	1.90e-01	1.00e+00	2.255	1	6	171
GO:0030424	axon	1.91e-01	1.00e+00	2.246	1	3	172
GO:0006886	intracellular protein transport	1.92e-01	1.00e+00	2.238	1	4	173
GO:0003714	transcription corepressor activity	1.98e-01	1.00e+00	2.189	1	7	179
GO:0031625	ubiquitin protein ligase binding	1.99e-01	1.00e+00	2.181	1	13	180
GO:0006367	transcription initiation from RNA polymerase II promoter	2.03e-01	1.00e+00	2.149	1	8	184
GO:0003924	GTPase activity	2.22e-01	1.00e+00	2.007	1	9	203
GO:0030168	platelet activation	2.23e-01	1.00e+00	1.993	1	9	205
GO:0003677	DNA binding	2.27e-01	1.00e+00	0.858	3	26	1351
GO:0005524	ATP binding	2.28e-01	1.00e+00	0.854	3	46	1354
GO:0001701	in utero embryonic development	2.28e-01	1.00e+00	1.958	1	6	210
GO:0003700	sequence-specific DNA binding transcription factor activity	2.33e-01	1.00e+00	1.126	2	11	748
GO:0006184	GTP catabolic process	2.38e-01	1.00e+00	1.891	1	9	220
GO:0007067	mitotic nuclear division	2.48e-01	1.00e+00	1.821	1	13	231
GO:0005759	mitochondrial matrix	2.50e-01	1.00e+00	1.808	1	12	233
GO:0003713	transcription coactivator activity	2.56e-01	1.00e+00	1.772	1	10	239
GO:0008134	transcription factor binding	2.62e-01	1.00e+00	1.730	1	8	246
GO:0000166	nucleotide binding	2.86e-01	1.00e+00	1.585	1	6	272
GO:0043065	positive regulation of apoptotic process	2.87e-01	1.00e+00	1.574	1	8	274
GO:0003779	actin binding	2.88e-01	1.00e+00	1.569	1	7	275
GO:0019899	enzyme binding	3.00e-01	1.00e+00	1.503	1	11	288
GO:0006200	ATP catabolic process	3.13e-01	1.00e+00	1.429	1	14	303
GO:0005856	cytoskeleton	3.20e-01	1.00e+00	1.392	1	8	311
GO:0030154	cell differentiation	3.31e-01	1.00e+00	1.328	1	5	325
GO:0005525	GTP binding	3.34e-01	1.00e+00	1.315	1	11	328
GO:0005813	centrosome	3.43e-01	1.00e+00	1.267	1	12	339
GO:0008285	negative regulation of cell proliferation	3.66e-01	1.00e+00	1.153	1	11	367
GO:0007155	cell adhesion	3.79e-01	1.00e+00	1.088	1	8	384
GO:0046982	protein heterodimerization activity	3.91e-01	1.00e+00	1.032	1	11	399
GO:0006355	regulation of transcription, DNA-templated	3.96e-01	1.00e+00	0.564	2	17	1104
GO:0045892	negative regulation of transcription, DNA-templated	4.09e-01	1.00e+00	0.945	1	14	424
GO:0006468	protein phosphorylation	4.41e-01	1.00e+00	0.805	1	10	467
GO:0055114	oxidation-reduction process	4.50e-01	1.00e+00	0.763	1	11	481
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.21e-01	1.00e+00	0.470	1	12	589
GO:0005783	endoplasmic reticulum	5.33e-01	1.00e+00	0.420	1	9	610
GO:0007165	signal transduction	6.99e-01	1.00e+00	-0.219	1	17	950
GO:0005739	mitochondrion	7.34e-01	1.00e+00	-0.358	1	24	1046
GO:0008270	zinc ion binding	7.42e-01	1.00e+00	-0.387	1	12	1067
GO:0046872	metal ion binding	8.48e-01	1.00e+00	-0.844	1	24	1465
GO:0006351	transcription, DNA-templated	8.71e-01	1.00e+00	-0.958	1	25	1585
GO:0005886	plasma membrane	9.78e-01	1.00e+00	-1.796	1	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-7167

Interacting subnets

Genes (20)

Interactions (53)

Related GO terms (356)