meta-int-snw-9527

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-4800	wolf-screen-ratio-mammosphere-adherent	0.833	7.78e-07	2.65e-03	5.08e-03	7	5
int-snw-9527	wolf-screen-ratio-mammosphere-adherent	0.934	1.77e-15	2.52e-03	4.06e-02	10	9
reg-snw-2547	wolf-screen-ratio-mammosphere-adherent	0.862	2.49e-07	1.43e-03	2.94e-03	5	4

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-9527 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
COPA	1314	7	0.434	0.833	170	TF	Yes	-
RPL8	6132	24	0.778	0.874	234	TF	Yes	-
HNRNPC	3183	108	1.812	0.973	181	-	Yes	-
TP53	7157	23	0.432	0.833	665	TF	-	-
RPL6	6128	37	0.844	1.113	164	-	Yes	-
TUBA1C	84790	5	0.966	0.993	91	-	Yes	-
GOSR1	9527	3	-0.022	0.934	176	-	-	-
RPL11	6135	21	0.718	1.017	200	-	Yes	-
NFYA	4800	7	0.198	0.833	80	TF	-	-
CCNA2	890	54	0.550	0.973	246	TF	Yes	-
CLTC	1213	56	0.884	1.138	247	-	Yes	-
XRCC6	2547	2	0.031	0.862	63	TF	-	-
RPL14	9045	49	1.250	1.113	166	-	Yes	-
ACTB	60	134	1.153	1.151	610	-	Yes	-
POLR2H	5437	2	0.775	0.862	14	-	Yes	-
HSPD1	3329	70	0.913	1.035	325	-	Yes	-

Interactions (36)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	RPL11	6135	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow
RPL14	9045	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
ACTB	60	NFYA	4800	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot
ACTB	60	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
XRCC6	2547	RPL8	6132	pd	<>	reg.ITFP.txt: no annot
RPL8	6132	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
COPA	1314	RPL11	6135	pp	--	int.I2D: BioGrid_Yeast
RPL6	6128	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
XRCC6	2547	HSPD1	3329	pd	>	reg.ITFP.txt: no annot
RPL11	6135	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPC	3183	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
RPL8	6132	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPL8	6132	RPL11	6135	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium, IntAct_Yeast
XRCC6	2547	TP53	7157	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, BIND, HPRD, IntAct, BCI; int.Ravasi: -; int.HPRD: in vivo
HNRNPC	3183	TP53	7157	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
RPL11	6135	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
CLTC	1213	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
XRCC6	2547	POLR2H	5437	pd	>	reg.ITFP.txt: no annot
XRCC6	2547	HNRNPC	3183	pd	>	reg.ITFP.txt: no annot
RPL6	6128	RPL8	6132	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
COPA	1314	RPL14	9045	pd	>	reg.ITFP.txt: no annot
NFYA	4800	TP53	7157	pd	>	reg.pazar.txt: no annot
NFYA	4800	TP53	7157	pp	--	int.Intact: MI:0914(association), MI:0915(physical association), MI:0403(colocalization); int.I2D: BioGrid, HPRD, IntAct, BCI; int.Ravasi: -; int.HPRD: in vivo
HSPD1	3329	TP53	7157	pp	--	int.Intact: MI:0914(association)
ACTB	60	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast
CCNA2	890	TP53	7157	pp	--	int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro
CLTC	1213	XRCC6	2547	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BIND, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
RPL6	6128	RPL11	6135	pp	--	int.I2D: BioGrid_Yeast
RPL11	6135	TP53	7157	pp	--	int.I2D: BioGrid
CCNA2	890	NFYA	4800	pd	<	reg.TRANSFAC.txt: no annot
GOSR1	9527	TUBA1C	84790	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HSPD1	3329	GOSR1	9527	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	NFYA	4800	pd	>	reg.ITFP.txt: no annot

Related GO terms (345)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	1.39e-08	2.27e-04	3.918	8	55	540
GO:0016020	membrane	5.34e-08	8.72e-04	2.684	11	80	1746
GO:0022625	cytosolic large ribosomal subunit	1.27e-07	2.07e-03	6.380	4	5	49
GO:0005829	cytosol	2.14e-07	3.49e-03	2.256	12	125	2562
GO:0019083	viral transcription	9.79e-07	1.60e-02	5.655	4	8	81
GO:0006415	translational termination	1.31e-06	2.13e-02	5.551	4	8	87
GO:0006414	translational elongation	1.71e-06	2.78e-02	5.455	4	11	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.67e-06	4.36e-02	5.294	4	8	104
GO:0044822	poly(A) RNA binding	2.82e-06	4.60e-02	2.920	8	50	1078
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.85e-06	6.29e-02	5.162	4	10	114
GO:0019058	viral life cycle	3.99e-06	6.51e-02	5.149	4	10	115
GO:0044267	cellular protein metabolic process	4.67e-06	7.62e-02	3.628	6	24	495
GO:0006413	translational initiation	6.69e-06	1.09e-01	4.961	4	12	131
GO:0043234	protein complex	7.51e-06	1.23e-01	4.088	5	17	300
GO:0003735	structural constituent of ribosome	8.96e-06	1.46e-01	4.855	4	8	141
GO:0003723	RNA binding	1.70e-05	2.77e-01	3.845	5	19	355
GO:0010467	gene expression	2.61e-05	4.26e-01	3.194	6	58	669
GO:0005654	nucleoplasm	4.01e-05	6.55e-01	2.705	7	83	1095
GO:0016071	mRNA metabolic process	5.43e-05	8.86e-01	4.194	4	34	223
GO:0006412	translation	6.66e-05	1.00e+00	4.118	4	15	235
GO:0042273	ribosomal large subunit biogenesis	6.98e-05	1.00e+00	7.294	2	4	13
GO:0016070	RNA metabolic process	8.07e-05	1.00e+00	4.046	4	34	247
GO:0036464	cytoplasmic ribonucleoprotein granule	2.06e-04	1.00e+00	6.535	2	4	22
GO:0019901	protein kinase binding	2.19e-04	1.00e+00	3.673	4	21	320
GO:0043044	ATP-dependent chromatin remodeling	2.25e-04	1.00e+00	6.471	2	4	23
GO:0000790	nuclear chromatin	2.74e-04	1.00e+00	4.524	3	7	133
GO:0019843	rRNA binding	3.12e-04	1.00e+00	6.240	2	3	27
GO:0031492	nucleosomal DNA binding	3.36e-04	1.00e+00	6.187	2	4	28
GO:0061024	membrane organization	3.61e-04	1.00e+00	4.390	3	5	146
GO:0005925	focal adhesion	3.81e-04	1.00e+00	3.463	4	18	370
GO:0005198	structural molecule activity	4.63e-04	1.00e+00	4.267	3	4	159
GO:0051084	'de novo' posttranslational protein folding	5.88e-04	1.00e+00	5.785	2	4	37
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	9.80e-04	1.00e+00	9.994	1	1	1
GO:0048291	isotype switching to IgG isotypes	9.80e-04	1.00e+00	9.994	1	1	1
GO:0002368	B cell cytokine production	9.80e-04	1.00e+00	9.994	1	1	1
GO:0045893	positive regulation of transcription, DNA-templated	1.07e-03	1.00e+00	3.067	4	17	487
GO:0003684	damaged DNA binding	1.12e-03	1.00e+00	5.322	2	11	51
GO:0003725	double-stranded RNA binding	1.25e-03	1.00e+00	5.240	2	6	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.25e-03	1.00e+00	5.240	2	5	54
GO:0002039	p53 binding	1.30e-03	1.00e+00	5.213	2	7	55
GO:0051087	chaperone binding	1.49e-03	1.00e+00	5.112	2	6	59
GO:0032481	positive regulation of type I interferon production	1.59e-03	1.00e+00	5.064	2	6	61
GO:0006302	double-strand break repair	1.65e-03	1.00e+00	5.040	2	8	62
GO:0097252	oligodendrocyte apoptotic process	1.96e-03	1.00e+00	8.994	1	1	2
GO:1901525	negative regulation of macromitophagy	1.96e-03	1.00e+00	8.994	1	1	2
GO:0043564	Ku70:Ku80 complex	1.96e-03	1.00e+00	8.994	1	1	2
GO:0090343	positive regulation of cell aging	1.96e-03	1.00e+00	8.994	1	1	2
GO:0071475	cellular hyperosmotic salinity response	1.96e-03	1.00e+00	8.994	1	1	2
GO:0006289	nucleotide-excision repair	2.03e-03	1.00e+00	4.886	2	12	69
GO:0007265	Ras protein signal transduction	2.40e-03	1.00e+00	4.766	2	3	75
GO:0035794	positive regulation of mitochondrial membrane permeability	2.94e-03	1.00e+00	8.409	1	1	3
GO:0051097	negative regulation of helicase activity	2.94e-03	1.00e+00	8.409	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	3
GO:0006458	'de novo' protein folding	2.94e-03	1.00e+00	8.409	1	1	3
GO:0035033	histone deacetylase regulator activity	2.94e-03	1.00e+00	8.409	1	1	3
GO:0002360	T cell lineage commitment	2.94e-03	1.00e+00	8.409	1	1	3
GO:0034103	regulation of tissue remodeling	2.94e-03	1.00e+00	8.409	1	1	3
GO:0030135	coated vesicle	2.94e-03	1.00e+00	8.409	1	1	3
GO:0071439	clathrin complex	2.94e-03	1.00e+00	8.409	1	1	3
GO:0005200	structural constituent of cytoskeleton	3.66e-03	1.00e+00	4.455	2	7	93
GO:0001649	osteoblast differentiation	3.81e-03	1.00e+00	4.425	2	6	95
GO:0006364	rRNA processing	3.89e-03	1.00e+00	4.409	2	5	96
GO:0032051	clathrin light chain binding	3.92e-03	1.00e+00	7.994	1	1	4
GO:0090403	oxidative stress-induced premature senescence	3.92e-03	1.00e+00	7.994	1	1	4
GO:0002326	B cell lineage commitment	3.92e-03	1.00e+00	7.994	1	1	4
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	3.92e-03	1.00e+00	7.994	1	2	4
GO:0016602	CCAAT-binding factor complex	3.92e-03	1.00e+00	7.994	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	3.92e-03	1.00e+00	7.994	1	1	4
GO:0006266	DNA ligation	4.89e-03	1.00e+00	7.673	1	1	5
GO:0003691	double-stranded telomeric DNA binding	4.89e-03	1.00e+00	7.673	1	1	5
GO:0001940	male pronucleus	4.89e-03	1.00e+00	7.673	1	1	5
GO:0097371	MDM2/MDM4 family protein binding	4.89e-03	1.00e+00	7.673	1	1	5
GO:0071481	cellular response to X-ray	4.89e-03	1.00e+00	7.673	1	1	5
GO:0046696	lipopolysaccharide receptor complex	4.89e-03	1.00e+00	7.673	1	1	5
GO:0003688	DNA replication origin binding	5.87e-03	1.00e+00	7.409	1	1	6
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0001221	transcription cofactor binding	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030130	clathrin coat of trans-Golgi network vesicle	5.87e-03	1.00e+00	7.409	1	1	6
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0002309	T cell proliferation involved in immune response	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030118	clathrin coat	5.87e-03	1.00e+00	7.409	1	1	6
GO:0070419	nonhomologous end joining complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0030957	Tat protein binding	5.87e-03	1.00e+00	7.409	1	4	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	5.87e-03	1.00e+00	7.409	1	1	6
GO:0070245	positive regulation of thymocyte apoptotic process	5.87e-03	1.00e+00	7.409	1	1	6
GO:0007406	negative regulation of neuroblast proliferation	5.87e-03	1.00e+00	7.409	1	1	6
GO:0070062	extracellular vesicular exosome	6.49e-03	1.00e+00	1.505	7	98	2516
GO:0001939	female pronucleus	6.84e-03	1.00e+00	7.187	1	1	7
GO:0030157	pancreatic juice secretion	6.84e-03	1.00e+00	7.187	1	1	7
GO:0030132	clathrin coat of coated pit	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031497	chromatin assembly	6.84e-03	1.00e+00	7.187	1	1	7
GO:0031982	vesicle	7.45e-03	1.00e+00	3.928	2	10	134
GO:0003677	DNA binding	7.77e-03	1.00e+00	1.917	5	26	1351
GO:0001055	RNA polymerase II activity	7.82e-03	1.00e+00	6.994	1	3	8
GO:0000733	DNA strand renaturation	7.82e-03	1.00e+00	6.994	1	1	8
GO:0070688	MLL5-L complex	7.82e-03	1.00e+00	6.994	1	1	8
GO:0075713	establishment of integrated proviral latency	7.82e-03	1.00e+00	6.994	1	2	8
GO:0000783	nuclear telomere cap complex	8.79e-03	1.00e+00	6.825	1	1	9
GO:0010389	regulation of G2/M transition of mitotic cell cycle	8.79e-03	1.00e+00	6.825	1	1	9
GO:0006983	ER overload response	8.79e-03	1.00e+00	6.825	1	2	9
GO:0031065	positive regulation of histone deacetylation	8.79e-03	1.00e+00	6.825	1	1	9
GO:0033151	V(D)J recombination	8.79e-03	1.00e+00	6.825	1	1	9
GO:0006457	protein folding	9.14e-03	1.00e+00	3.775	2	8	149
GO:0043032	positive regulation of macrophage activation	9.76e-03	1.00e+00	6.673	1	1	10
GO:0090399	replicative senescence	9.76e-03	1.00e+00	6.673	1	1	10
GO:2000648	positive regulation of stem cell proliferation	9.76e-03	1.00e+00	6.673	1	1	10
GO:0046902	regulation of mitochondrial membrane permeability	9.76e-03	1.00e+00	6.673	1	1	10
GO:0051604	protein maturation	9.76e-03	1.00e+00	6.673	1	1	10
GO:0032727	positive regulation of interferon-alpha production	1.07e-02	1.00e+00	6.535	1	1	11
GO:0008340	determination of adult lifespan	1.07e-02	1.00e+00	6.535	1	1	11
GO:0071850	mitotic cell cycle arrest	1.07e-02	1.00e+00	6.535	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.07e-02	1.00e+00	6.535	1	3	11
GO:0001054	RNA polymerase I activity	1.07e-02	1.00e+00	6.535	1	3	11
GO:0045120	pronucleus	1.07e-02	1.00e+00	6.535	1	1	11
GO:0033762	response to glucagon	1.07e-02	1.00e+00	6.535	1	1	11
GO:2000036	regulation of stem cell maintenance	1.07e-02	1.00e+00	6.535	1	2	11
GO:0000398	mRNA splicing, via spliceosome	1.11e-02	1.00e+00	3.628	2	12	165
GO:0005515	protein binding	1.13e-02	1.00e+00	0.873	11	172	6127
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.15e-02	1.00e+00	3.602	2	5	168
GO:0070935	3'-UTR-mediated mRNA stabilization	1.17e-02	1.00e+00	6.409	1	2	12
GO:0005736	DNA-directed RNA polymerase I complex	1.17e-02	1.00e+00	6.409	1	3	12
GO:0070266	necroptotic process	1.17e-02	1.00e+00	6.409	1	1	12
GO:0032461	positive regulation of protein oligomerization	1.17e-02	1.00e+00	6.409	1	1	12
GO:0009303	rRNA transcription	1.17e-02	1.00e+00	6.409	1	1	12
GO:0044212	transcription regulatory region DNA binding	1.19e-02	1.00e+00	3.577	2	6	171
GO:0006886	intracellular protein transport	1.22e-02	1.00e+00	3.560	2	4	173
GO:0048205	COPI coating of Golgi vesicle	1.27e-02	1.00e+00	6.294	1	1	13
GO:0001530	lipopolysaccharide binding	1.27e-02	1.00e+00	6.294	1	2	13
GO:0030126	COPI vesicle coat	1.27e-02	1.00e+00	6.294	1	1	13
GO:0008266	poly(U) RNA binding	1.27e-02	1.00e+00	6.294	1	1	13
GO:0051131	chaperone-mediated protein complex assembly	1.27e-02	1.00e+00	6.294	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.36e-02	1.00e+00	6.187	1	4	14
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	1.36e-02	1.00e+00	6.187	1	2	14
GO:0030705	cytoskeleton-dependent intracellular transport	1.36e-02	1.00e+00	6.187	1	1	14
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.36e-02	1.00e+00	6.187	1	1	14
GO:0030330	DNA damage response, signal transduction by p53 class mediator	1.36e-02	1.00e+00	6.187	1	1	14
GO:0007095	mitotic G2 DNA damage checkpoint	1.36e-02	1.00e+00	6.187	1	1	14
GO:0009651	response to salt stress	1.36e-02	1.00e+00	6.187	1	2	14
GO:0048568	embryonic organ development	1.36e-02	1.00e+00	6.187	1	1	14
GO:0042026	protein refolding	1.46e-02	1.00e+00	6.088	1	2	15
GO:0005665	DNA-directed RNA polymerase II, core complex	1.56e-02	1.00e+00	5.994	1	4	16
GO:0050998	nitric-oxide synthase binding	1.56e-02	1.00e+00	5.994	1	1	16
GO:0001056	RNA polymerase III activity	1.56e-02	1.00e+00	5.994	1	3	16
GO:0042149	cellular response to glucose starvation	1.65e-02	1.00e+00	5.907	1	1	17
GO:0005666	DNA-directed RNA polymerase III complex	1.65e-02	1.00e+00	5.907	1	3	17
GO:0050870	positive regulation of T cell activation	1.65e-02	1.00e+00	5.907	1	1	17
GO:0006891	intra-Golgi vesicle-mediated transport	1.65e-02	1.00e+00	5.907	1	1	17
GO:0006386	termination of RNA polymerase III transcription	1.75e-02	1.00e+00	5.825	1	3	18
GO:0006385	transcription elongation from RNA polymerase III promoter	1.75e-02	1.00e+00	5.825	1	3	18
GO:0051721	protein phosphatase 2A binding	1.75e-02	1.00e+00	5.825	1	1	18
GO:0006303	double-strand break repair via nonhomologous end joining	1.75e-02	1.00e+00	5.825	1	3	18
GO:0005657	replication fork	1.75e-02	1.00e+00	5.825	1	3	18
GO:0035035	histone acetyltransferase binding	1.85e-02	1.00e+00	5.747	1	1	19
GO:0071158	positive regulation of cell cycle arrest	1.85e-02	1.00e+00	5.747	1	1	19
GO:0032733	positive regulation of interleukin-10 production	1.85e-02	1.00e+00	5.747	1	1	19
GO:0010165	response to X-ray	1.85e-02	1.00e+00	5.747	1	2	19
GO:0050769	positive regulation of neurogenesis	1.85e-02	1.00e+00	5.747	1	1	19
GO:0002931	response to ischemia	1.94e-02	1.00e+00	5.673	1	1	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	1.94e-02	1.00e+00	5.673	1	1	20
GO:0008156	negative regulation of DNA replication	2.04e-02	1.00e+00	5.602	1	1	21
GO:0007369	gastrulation	2.04e-02	1.00e+00	5.602	1	1	21
GO:0045087	innate immune response	2.08e-02	1.00e+00	2.313	3	20	616
GO:0007067	mitotic nuclear division	2.10e-02	1.00e+00	3.143	2	13	231
GO:0008380	RNA splicing	2.12e-02	1.00e+00	3.136	2	13	232
GO:0005759	mitochondrial matrix	2.13e-02	1.00e+00	3.130	2	12	233
GO:0005669	transcription factor TFIID complex	2.14e-02	1.00e+00	5.535	1	1	22
GO:0090200	positive regulation of release of cytochrome c from mitochondria	2.14e-02	1.00e+00	5.535	1	1	22
GO:0030863	cortical cytoskeleton	2.14e-02	1.00e+00	5.535	1	1	22
GO:0006362	transcription elongation from RNA polymerase I promoter	2.23e-02	1.00e+00	5.471	1	3	23
GO:0001836	release of cytochrome c from mitochondria	2.33e-02	1.00e+00	5.409	1	2	24
GO:0006363	termination of RNA polymerase I transcription	2.33e-02	1.00e+00	5.409	1	3	24
GO:0048147	negative regulation of fibroblast proliferation	2.33e-02	1.00e+00	5.409	1	1	24
GO:0005484	SNAP receptor activity	2.33e-02	1.00e+00	5.409	1	2	24
GO:0000060	protein import into nucleus, translocation	2.33e-02	1.00e+00	5.409	1	4	24
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.33e-02	1.00e+00	5.409	1	1	24
GO:0042100	B cell proliferation	2.42e-02	1.00e+00	5.351	1	1	25
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.42e-02	1.00e+00	5.351	1	1	25
GO:0007569	cell aging	2.42e-02	1.00e+00	5.351	1	2	25
GO:0071479	cellular response to ionizing radiation	2.42e-02	1.00e+00	5.351	1	1	25
GO:0042113	B cell activation	2.42e-02	1.00e+00	5.351	1	2	25
GO:0032735	positive regulation of interleukin-12 production	2.42e-02	1.00e+00	5.351	1	1	25
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	2.52e-02	1.00e+00	5.294	1	3	26
GO:0006361	transcription initiation from RNA polymerase I promoter	2.52e-02	1.00e+00	5.294	1	3	26
GO:0004003	ATP-dependent DNA helicase activity	2.62e-02	1.00e+00	5.240	1	3	27
GO:0051258	protein polymerization	2.62e-02	1.00e+00	5.240	1	2	27
GO:0006281	DNA repair	2.69e-02	1.00e+00	2.950	2	22	264
GO:0001046	core promoter sequence-specific DNA binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0007017	microtubule-based process	2.71e-02	1.00e+00	5.187	1	3	28
GO:0019894	kinesin binding	2.71e-02	1.00e+00	5.187	1	1	28
GO:0010332	response to gamma radiation	2.81e-02	1.00e+00	5.136	1	2	29
GO:0003730	mRNA 3'-UTR binding	2.81e-02	1.00e+00	5.136	1	2	29
GO:0030669	clathrin-coated endocytic vesicle membrane	2.81e-02	1.00e+00	5.136	1	1	29
GO:0043065	positive regulation of apoptotic process	2.89e-02	1.00e+00	2.896	2	8	274
GO:0006370	7-methylguanosine mRNA capping	2.90e-02	1.00e+00	5.088	1	4	30
GO:0051262	protein tetramerization	2.90e-02	1.00e+00	5.088	1	3	30
GO:0034504	protein localization to nucleus	2.90e-02	1.00e+00	5.088	1	2	30
GO:0006360	transcription from RNA polymerase I promoter	2.90e-02	1.00e+00	5.088	1	4	30
GO:0021549	cerebellum development	2.90e-02	1.00e+00	5.088	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.90e-02	1.00e+00	5.088	1	2	30
GO:0031623	receptor internalization	3.00e-02	1.00e+00	5.040	1	1	31
GO:0046677	response to antibiotic	3.00e-02	1.00e+00	5.040	1	2	31
GO:0016604	nuclear body	3.00e-02	1.00e+00	5.040	1	2	31
GO:0031201	SNARE complex	3.00e-02	1.00e+00	5.040	1	2	31
GO:0034644	cellular response to UV	3.09e-02	1.00e+00	4.994	1	5	32
GO:0033572	transferrin transport	3.09e-02	1.00e+00	4.994	1	6	32
GO:0030971	receptor tyrosine kinase binding	3.19e-02	1.00e+00	4.950	1	2	33
GO:0033077	T cell differentiation in thymus	3.19e-02	1.00e+00	4.950	1	2	33
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	3.19e-02	1.00e+00	4.950	1	1	33
GO:0001085	RNA polymerase II transcription factor binding	3.28e-02	1.00e+00	4.907	1	2	34
GO:0005801	cis-Golgi network	3.38e-02	1.00e+00	4.865	1	1	35
GO:0032588	trans-Golgi network membrane	3.47e-02	1.00e+00	4.825	1	1	36
GO:0034332	adherens junction organization	3.47e-02	1.00e+00	4.825	1	1	36
GO:0051402	neuron apoptotic process	3.47e-02	1.00e+00	4.825	1	2	36
GO:0001895	retina homeostasis	3.47e-02	1.00e+00	4.825	1	1	36
GO:0006605	protein targeting	3.47e-02	1.00e+00	4.825	1	2	36
GO:0032755	positive regulation of interleukin-6 production	3.47e-02	1.00e+00	4.825	1	2	36
GO:0001756	somitogenesis	3.66e-02	1.00e+00	4.747	1	1	38
GO:0070527	platelet aggregation	3.66e-02	1.00e+00	4.747	1	2	38
GO:0006383	transcription from RNA polymerase III promoter	3.76e-02	1.00e+00	4.709	1	3	39
GO:0006284	base-excision repair	3.76e-02	1.00e+00	4.709	1	7	39
GO:0032729	positive regulation of interferon-gamma production	3.76e-02	1.00e+00	4.709	1	2	39
GO:0005524	ATP binding	3.83e-02	1.00e+00	1.591	4	46	1354
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	3.85e-02	1.00e+00	4.673	1	2	40
GO:0005881	cytoplasmic microtubule	3.95e-02	1.00e+00	4.637	1	2	41
GO:0042147	retrograde transport, endosome to Golgi	4.04e-02	1.00e+00	4.602	1	3	42
GO:0032508	DNA duplex unwinding	4.04e-02	1.00e+00	4.602	1	4	42
GO:0042110	T cell activation	4.14e-02	1.00e+00	4.568	1	3	43
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.22e-02	1.00e+00	1.916	3	19	811
GO:0048146	positive regulation of fibroblast proliferation	4.23e-02	1.00e+00	4.535	1	2	44
GO:0034613	cellular protein localization	4.23e-02	1.00e+00	4.535	1	1	44
GO:0006892	post-Golgi vesicle-mediated transport	4.23e-02	1.00e+00	4.535	1	2	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4.23e-02	1.00e+00	4.535	1	2	44
GO:0050434	positive regulation of viral transcription	4.23e-02	1.00e+00	4.535	1	5	44
GO:0021762	substantia nigra development	4.42e-02	1.00e+00	4.471	1	1	46
GO:0030136	clathrin-coated vesicle	4.42e-02	1.00e+00	4.471	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	4.42e-02	1.00e+00	4.471	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	4.42e-02	1.00e+00	4.471	1	8	46
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	4.51e-02	1.00e+00	4.440	1	3	47
GO:0048511	rhythmic process	4.51e-02	1.00e+00	4.440	1	2	47
GO:0005507	copper ion binding	4.61e-02	1.00e+00	4.409	1	2	48
GO:0031100	organ regeneration	4.79e-02	1.00e+00	4.351	1	4	50
GO:0035690	cellular response to drug	4.79e-02	1.00e+00	4.351	1	2	50
GO:0006986	response to unfolded protein	4.89e-02	1.00e+00	4.322	1	2	51
GO:0005905	coated pit	4.89e-02	1.00e+00	4.322	1	2	51
GO:0097193	intrinsic apoptotic signaling pathway	5.26e-02	1.00e+00	4.213	1	4	55
GO:0006888	ER to Golgi vesicle-mediated transport	5.26e-02	1.00e+00	4.213	1	2	55
GO:0008104	protein localization	5.35e-02	1.00e+00	4.187	1	3	56
GO:0045216	cell-cell junction organization	5.63e-02	1.00e+00	4.112	1	2	59
GO:0000723	telomere maintenance	5.63e-02	1.00e+00	4.112	1	8	59
GO:0019903	protein phosphatase binding	6.00e-02	1.00e+00	4.017	1	4	63
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	6.10e-02	1.00e+00	3.994	1	1	64
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.19e-02	1.00e+00	3.972	1	22	65
GO:0045892	negative regulation of transcription, DNA-templated	6.36e-02	1.00e+00	2.267	2	14	424
GO:0006368	transcription elongation from RNA polymerase II promoter	6.37e-02	1.00e+00	3.928	1	6	67
GO:0030141	secretory granule	6.37e-02	1.00e+00	3.928	1	2	67
GO:0006366	transcription from RNA polymerase II promoter	6.38e-02	1.00e+00	2.263	2	12	425
GO:0003697	single-stranded DNA binding	6.56e-02	1.00e+00	3.886	1	9	69
GO:0043066	negative regulation of apoptotic process	6.60e-02	1.00e+00	2.236	2	30	433
GO:0035264	multicellular organism growth	6.65e-02	1.00e+00	3.865	1	1	70
GO:0034329	cell junction assembly	6.74e-02	1.00e+00	3.845	1	1	71
GO:0005634	nucleus	6.90e-02	1.00e+00	0.757	8	131	4828
GO:0032355	response to estradiol	6.92e-02	1.00e+00	3.805	1	5	73
GO:0000785	chromatin	6.92e-02	1.00e+00	3.805	1	5	73
GO:0002020	protease binding	7.02e-02	1.00e+00	3.785	1	4	74
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	7.11e-02	1.00e+00	3.766	1	1	75
GO:0005615	extracellular space	7.24e-02	1.00e+00	1.599	3	17	1010
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	7.29e-02	1.00e+00	3.728	1	5	77
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7.29e-02	1.00e+00	3.728	1	6	77
GO:0007596	blood coagulation	7.44e-02	1.00e+00	2.136	2	14	464
GO:0071013	catalytic step 2 spliceosome	7.47e-02	1.00e+00	3.691	1	7	79
GO:0005730	nucleolus	7.50e-02	1.00e+00	1.277	4	70	1684
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.56e-02	1.00e+00	3.673	1	2	80
GO:0051301	cell division	7.66e-02	1.00e+00	3.655	1	6	81
GO:0005681	spliceosomal complex	7.84e-02	1.00e+00	3.619	1	3	83
GO:0005179	hormone activity	7.93e-02	1.00e+00	3.602	1	1	84
GO:0047485	protein N-terminus binding	8.11e-02	1.00e+00	3.568	1	4	86
GO:0006898	receptor-mediated endocytosis	8.11e-02	1.00e+00	3.568	1	2	86
GO:0042802	identical protein binding	8.21e-02	1.00e+00	2.055	2	18	491
GO:0050821	protein stabilization	8.56e-02	1.00e+00	3.487	1	2	91
GO:0003690	double-stranded DNA binding	8.56e-02	1.00e+00	3.487	1	4	91
GO:0016363	nuclear matrix	8.65e-02	1.00e+00	3.471	1	11	92
GO:0016605	PML body	8.65e-02	1.00e+00	3.471	1	5	92
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	8.65e-02	1.00e+00	3.471	1	4	92
GO:0042470	melanosome	8.65e-02	1.00e+00	3.471	1	10	92
GO:0006928	cellular component movement	8.65e-02	1.00e+00	3.471	1	7	92
GO:0051082	unfolded protein binding	8.92e-02	1.00e+00	3.425	1	6	95
GO:0006355	regulation of transcription, DNA-templated	8.94e-02	1.00e+00	1.471	3	17	1104
GO:0071456	cellular response to hypoxia	9.19e-02	1.00e+00	3.380	1	4	98
GO:0014069	postsynaptic density	9.90e-02	1.00e+00	3.267	1	1	106
GO:0006461	protein complex assembly	1.03e-01	1.00e+00	3.200	1	6	111
GO:0030308	negative regulation of cell growth	1.05e-01	1.00e+00	3.174	1	6	113
GO:0030529	ribonucleoprotein complex	1.06e-01	1.00e+00	3.162	1	8	114
GO:0005819	spindle	1.06e-01	1.00e+00	3.162	1	7	114
GO:0072562	blood microparticle	1.08e-01	1.00e+00	3.136	1	4	116
GO:0006325	chromatin organization	1.14e-01	1.00e+00	3.052	1	4	123
GO:0007219	Notch signaling pathway	1.16e-01	1.00e+00	3.029	1	4	125
GO:0007050	cell cycle arrest	1.17e-01	1.00e+00	3.017	1	7	126
GO:0007179	transforming growth factor beta receptor signaling pathway	1.20e-01	1.00e+00	2.972	1	3	130
GO:0000086	G2/M transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	7	137
GO:0044255	cellular lipid metabolic process	1.29e-01	1.00e+00	2.865	1	4	140
GO:0016887	ATPase activity	1.32e-01	1.00e+00	2.825	1	7	144
GO:0042981	regulation of apoptotic process	1.38e-01	1.00e+00	2.756	1	26	151
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.38e-01	1.00e+00	2.756	1	2	151
GO:0005769	early endosome	1.44e-01	1.00e+00	2.691	1	2	158
GO:0006974	cellular response to DNA damage stimulus	1.44e-01	1.00e+00	2.691	1	8	158
GO:0008022	protein C-terminus binding	1.47e-01	1.00e+00	2.664	1	4	161
GO:0007420	brain development	1.56e-01	1.00e+00	2.568	1	1	172
GO:0030424	axon	1.56e-01	1.00e+00	2.568	1	3	172
GO:0005667	transcription factor complex	1.61e-01	1.00e+00	2.519	1	6	178
GO:0031625	ubiquitin protein ligase binding	1.63e-01	1.00e+00	2.503	1	13	180
GO:0003700	sequence-specific DNA binding transcription factor activity	1.65e-01	1.00e+00	1.448	2	11	748
GO:0006367	transcription initiation from RNA polymerase II promoter	1.66e-01	1.00e+00	2.471	1	8	184
GO:0005737	cytoplasm	1.73e-01	1.00e+00	0.622	6	98	3976
GO:0003924	GTPase activity	1.82e-01	1.00e+00	2.329	1	9	203
GO:0001701	in utero embryonic development	1.87e-01	1.00e+00	2.280	1	6	210
GO:0006184	GTP catabolic process	1.95e-01	1.00e+00	2.213	1	9	220
GO:0008134	transcription factor binding	2.16e-01	1.00e+00	2.052	1	8	246
GO:0005874	microtubule	2.25e-01	1.00e+00	1.983	1	6	258
GO:0000166	nucleotide binding	2.36e-01	1.00e+00	1.907	1	6	272
GO:0019899	enzyme binding	2.48e-01	1.00e+00	1.825	1	11	288
GO:0005743	mitochondrial inner membrane	2.57e-01	1.00e+00	1.766	1	5	300
GO:0006200	ATP catabolic process	2.59e-01	1.00e+00	1.751	1	14	303
GO:0005856	cytoskeleton	2.65e-01	1.00e+00	1.714	1	8	311
GO:0005739	mitochondrion	2.74e-01	1.00e+00	0.964	2	24	1046
GO:0030154	cell differentiation	2.75e-01	1.00e+00	1.650	1	5	325
GO:0007411	axon guidance	2.77e-01	1.00e+00	1.641	1	9	327
GO:0005525	GTP binding	2.77e-01	1.00e+00	1.637	1	11	328
GO:0008283	cell proliferation	2.80e-01	1.00e+00	1.624	1	12	331
GO:0003682	chromatin binding	2.82e-01	1.00e+00	1.611	1	12	334
GO:0007275	multicellular organismal development	2.89e-01	1.00e+00	1.568	1	5	344
GO:0015031	protein transport	2.98e-01	1.00e+00	1.515	1	4	357
GO:0008285	negative regulation of cell proliferation	3.05e-01	1.00e+00	1.475	1	11	367
GO:0000278	mitotic cell cycle	3.26e-01	1.00e+00	1.358	1	52	398
GO:0046982	protein heterodimerization activity	3.27e-01	1.00e+00	1.354	1	11	399
GO:0000139	Golgi membrane	3.33e-01	1.00e+00	1.322	1	2	408
GO:0009986	cell surface	3.43e-01	1.00e+00	1.273	1	9	422
GO:0006915	apoptotic process	4.35e-01	1.00e+00	0.837	1	34	571
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.45e-01	1.00e+00	0.792	1	12	589
GO:0005783	endoplasmic reticulum	4.57e-01	1.00e+00	0.742	1	9	610
GO:0005794	Golgi apparatus	4.78e-01	1.00e+00	0.650	1	14	650
GO:0008270	zinc ion binding	6.61e-01	1.00e+00	-0.065	1	12	1067
GO:0044281	small molecule metabolic process	7.34e-01	1.00e+00	-0.344	1	57	1295
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.474	2	38	2834
GO:0006351	transcription, DNA-templated	8.05e-01	1.00e+00	-0.636	1	25	1585
GO:0016021	integral component of membrane	9.29e-01	1.00e+00	-1.283	1	15	2483

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-9527

Interacting subnets

Genes (16)

Interactions (36)

Related GO terms (345)