reg-snw-2547

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.862	2.49e-07	1.43e-03	2.94e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-2547 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
POLR2H	5437	3	0.775	0.862	14	-	Yes	-
HSPD1	3329	4	0.913	0.875	39	-	Yes	-
[ XRCC6 ]	2547	1	0.031	0.862	63	TF	-	-
RPL8	6132	2	0.778	0.874	16	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
XRCC6	2547	POLR2H	5437	pd	>	reg.ITFP.txt: no annot
XRCC6	2547	HSPD1	3329	pd	>	reg.ITFP.txt: no annot
XRCC6	2547	HNRNPC	3183	pd	>	reg.ITFP.txt: no annot
XRCC6	2547	RPL8	6132	pd	<>	reg.ITFP.txt: no annot

Related GO terms (139)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016032	viral process	1.76e-05	1.72e-01	4.190	4	32	428
GO:0005829	cytosol	2.04e-04	1.00e+00	2.450	5	58	1787
GO:0044822	poly(A) RNA binding	2.08e-04	1.00e+00	3.289	4	25	799
GO:0032481	positive regulation of type I interferon production	2.34e-04	1.00e+00	6.347	2	5	48
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	5.12e-04	1.00e+00	10.931	1	1	1
GO:0048291	isotype switching to IgG isotypes	5.12e-04	1.00e+00	10.931	1	1	1
GO:0002368	B cell cytokine production	5.12e-04	1.00e+00	10.931	1	1	1
GO:0006458	'de novo' protein folding	1.02e-03	1.00e+00	9.931	1	1	2
GO:0043564	Ku70:Ku80 complex	1.02e-03	1.00e+00	9.931	1	1	2
GO:0071475	cellular hyperosmotic salinity response	1.02e-03	1.00e+00	9.931	1	1	2
GO:0016020	membrane	1.05e-03	1.00e+00	2.694	4	38	1207
GO:0010467	gene expression	1.51e-03	1.00e+00	3.453	3	31	535
GO:0003688	DNA replication origin binding	1.54e-03	1.00e+00	9.347	1	1	3
GO:0046696	lipopolysaccharide receptor complex	1.54e-03	1.00e+00	9.347	1	1	3
GO:0030135	coated vesicle	1.54e-03	1.00e+00	9.347	1	1	3
GO:0000398	mRNA splicing, via spliceosome	1.66e-03	1.00e+00	4.931	2	8	128
GO:0003691	double-stranded telomeric DNA binding	2.05e-03	1.00e+00	8.931	1	1	4
GO:0071481	cellular response to X-ray	2.05e-03	1.00e+00	8.931	1	1	4
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	2.05e-03	1.00e+00	8.931	1	2	4
GO:0006266	DNA ligation	2.56e-03	1.00e+00	8.610	1	1	5
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	2.56e-03	1.00e+00	8.610	1	1	5
GO:0008380	RNA splicing	2.74e-03	1.00e+00	4.565	2	7	165
GO:0070419	nonhomologous end joining complex	3.07e-03	1.00e+00	8.347	1	1	6
GO:0001055	RNA polymerase II activity	3.07e-03	1.00e+00	8.347	1	2	6
GO:0043032	positive regulation of macrophage activation	3.07e-03	1.00e+00	8.347	1	1	6
GO:0000783	nuclear telomere cap complex	3.58e-03	1.00e+00	8.124	1	1	7
GO:0033151	V(D)J recombination	3.58e-03	1.00e+00	8.124	1	2	7
GO:0032727	positive regulation of interferon-alpha production	4.09e-03	1.00e+00	7.931	1	1	8
GO:0075713	establishment of integrated proviral latency	4.09e-03	1.00e+00	7.931	1	2	8
GO:0051604	protein maturation	4.09e-03	1.00e+00	7.931	1	1	8
GO:0006281	DNA repair	4.13e-03	1.00e+00	4.266	2	19	203
GO:0043234	protein complex	4.41e-03	1.00e+00	4.217	2	8	210
GO:0001530	lipopolysaccharide binding	4.60e-03	1.00e+00	7.762	1	1	9
GO:0008266	poly(U) RNA binding	4.60e-03	1.00e+00	7.762	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	5.11e-03	1.00e+00	7.610	1	2	10
GO:0042026	protein refolding	5.11e-03	1.00e+00	7.610	1	1	10
GO:0001054	RNA polymerase I activity	5.11e-03	1.00e+00	7.610	1	2	10
GO:0051131	chaperone-mediated protein complex assembly	5.11e-03	1.00e+00	7.610	1	1	10
GO:0070935	3'-UTR-mediated mRNA stabilization	5.62e-03	1.00e+00	7.472	1	2	11
GO:0045120	pronucleus	5.62e-03	1.00e+00	7.472	1	1	11
GO:0003723	RNA binding	6.06e-03	1.00e+00	3.983	2	11	247
GO:0005654	nucleoplasm	6.27e-03	1.00e+00	2.742	3	55	876
GO:0032733	positive regulation of interleukin-10 production	6.64e-03	1.00e+00	7.231	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	6.64e-03	1.00e+00	7.231	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	6.64e-03	1.00e+00	7.231	1	2	13
GO:0001056	RNA polymerase III activity	6.64e-03	1.00e+00	7.231	1	2	13
GO:0006386	termination of RNA polymerase III transcription	7.15e-03	1.00e+00	7.124	1	2	14
GO:0019843	rRNA binding	7.15e-03	1.00e+00	7.124	1	1	14
GO:0050870	positive regulation of T cell activation	7.15e-03	1.00e+00	7.124	1	1	14
GO:0050769	positive regulation of neurogenesis	7.15e-03	1.00e+00	7.124	1	1	14
GO:0006385	transcription elongation from RNA polymerase III promoter	7.15e-03	1.00e+00	7.124	1	2	14
GO:0042113	B cell activation	8.17e-03	1.00e+00	6.931	1	1	16
GO:0042100	B cell proliferation	8.68e-03	1.00e+00	6.844	1	1	17
GO:0006303	double-strand break repair via nonhomologous end joining	9.18e-03	1.00e+00	6.762	1	4	18
GO:0043044	ATP-dependent chromatin remodeling	1.02e-02	1.00e+00	6.610	1	2	20
GO:0006362	transcription elongation from RNA polymerase I promoter	1.02e-02	1.00e+00	6.610	1	1	20
GO:0032735	positive regulation of interleukin-12 production	1.02e-02	1.00e+00	6.610	1	1	20
GO:0006363	termination of RNA polymerase I transcription	1.07e-02	1.00e+00	6.539	1	1	21
GO:0006361	transcription initiation from RNA polymerase I promoter	1.17e-02	1.00e+00	6.408	1	1	23
GO:0006370	7-methylguanosine mRNA capping	1.22e-02	1.00e+00	6.347	1	2	24
GO:0004003	ATP-dependent DNA helicase activity	1.27e-02	1.00e+00	6.288	1	2	25
GO:0003730	mRNA 3'-UTR binding	1.27e-02	1.00e+00	6.288	1	2	25
GO:0031492	nucleosomal DNA binding	1.27e-02	1.00e+00	6.288	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	1.38e-02	1.00e+00	6.177	1	2	27
GO:0032755	positive regulation of interleukin-6 production	1.38e-02	1.00e+00	6.177	1	1	27
GO:0032729	positive regulation of interferon-gamma production	1.43e-02	1.00e+00	6.124	1	1	28
GO:0006383	transcription from RNA polymerase III promoter	1.48e-02	1.00e+00	6.073	1	2	29
GO:0042110	T cell activation	1.68e-02	1.00e+00	5.887	1	1	33
GO:0050434	positive regulation of viral transcription	1.78e-02	1.00e+00	5.802	1	2	35
GO:0006986	response to unfolded protein	1.78e-02	1.00e+00	5.802	1	1	35
GO:0022625	cytosolic large ribosomal subunit	1.83e-02	1.00e+00	5.762	1	2	36
GO:0005905	coated pit	1.88e-02	1.00e+00	5.722	1	2	37
GO:0032508	DNA duplex unwinding	1.93e-02	1.00e+00	5.684	1	5	38
GO:0045087	innate immune response	1.95e-02	1.00e+00	3.111	2	7	452
GO:0006283	transcription-coupled nucleotide-excision repair	2.03e-02	1.00e+00	5.610	1	6	40
GO:0003684	damaged DNA binding	2.08e-02	1.00e+00	5.574	1	9	41
GO:0030141	secretory granule	2.23e-02	1.00e+00	5.472	1	1	44
GO:0051087	chaperone binding	2.28e-02	1.00e+00	5.440	1	3	45
GO:0003725	double-stranded RNA binding	2.28e-02	1.00e+00	5.440	1	3	45
GO:0002039	p53 binding	2.28e-02	1.00e+00	5.440	1	2	45
GO:0000723	telomere maintenance	2.38e-02	1.00e+00	5.377	1	8	47
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.48e-02	1.00e+00	5.317	1	3	49
GO:0006368	transcription elongation from RNA polymerase II promoter	2.63e-02	1.00e+00	5.231	1	3	52
GO:0006302	double-strand break repair	2.63e-02	1.00e+00	5.231	1	8	52
GO:0006289	nucleotide-excision repair	2.69e-02	1.00e+00	5.204	1	9	53
GO:0005681	spliceosomal complex	2.79e-02	1.00e+00	5.150	1	2	55
GO:0003697	single-stranded DNA binding	2.89e-02	1.00e+00	5.099	1	6	57
GO:0071013	catalytic step 2 spliceosome	3.09e-02	1.00e+00	5.001	1	5	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.09e-02	1.00e+00	5.001	1	1	61
GO:0019083	viral transcription	3.09e-02	1.00e+00	5.001	1	2	61
GO:0006415	translational termination	3.19e-02	1.00e+00	4.954	1	2	63
GO:0050821	protein stabilization	3.23e-02	1.00e+00	4.931	1	1	64
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	3.38e-02	1.00e+00	4.865	1	2	67
GO:0006414	translational elongation	3.48e-02	1.00e+00	4.823	1	2	69
GO:0051082	unfolded protein binding	3.53e-02	1.00e+00	4.802	1	4	70
GO:0001649	osteoblast differentiation	3.73e-02	1.00e+00	4.722	1	2	74
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.88e-02	1.00e+00	4.665	1	2	77
GO:0019058	viral life cycle	3.93e-02	1.00e+00	4.646	1	3	78
GO:0003690	double-stranded DNA binding	4.18e-02	1.00e+00	4.556	1	3	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.23e-02	1.00e+00	4.539	1	3	84
GO:0006413	translational initiation	4.97e-02	1.00e+00	4.302	1	4	99
GO:0016887	ATPase activity	5.02e-02	1.00e+00	4.288	1	6	100
GO:0003735	structural constituent of ribosome	5.46e-02	1.00e+00	4.163	1	2	109
GO:0005769	early endosome	5.46e-02	1.00e+00	4.163	1	1	109
GO:0000790	nuclear chromatin	5.46e-02	1.00e+00	4.163	1	3	109
GO:0008022	protein C-terminus binding	5.75e-02	1.00e+00	4.086	1	1	115
GO:0007420	brain development	5.95e-02	1.00e+00	4.037	1	1	119
GO:0005524	ATP binding	6.92e-02	1.00e+00	2.131	2	23	892
GO:0005759	mitochondrial matrix	6.92e-02	1.00e+00	3.813	1	5	139
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.06e-02	1.00e+00	3.782	1	2	142
GO:0044212	transcription regulatory region DNA binding	7.11e-02	1.00e+00	3.772	1	2	143
GO:0005667	transcription factor complex	7.31e-02	1.00e+00	3.732	1	3	147
GO:0003677	DNA binding	7.71e-02	1.00e+00	2.044	2	18	947
GO:0006367	transcription initiation from RNA polymerase II promoter	7.98e-02	1.00e+00	3.601	1	4	161
GO:0016071	mRNA metabolic process	8.41e-02	1.00e+00	3.522	1	21	170
GO:0000166	nucleotide binding	8.69e-02	1.00e+00	3.472	1	6	176
GO:0006412	translation	8.79e-02	1.00e+00	3.456	1	3	178
GO:0016070	RNA metabolic process	9.26e-02	1.00e+00	3.377	1	21	188
GO:0005743	mitochondrial inner membrane	9.69e-02	1.00e+00	3.309	1	3	197
GO:0043065	positive regulation of apoptotic process	9.93e-02	1.00e+00	3.273	1	3	202
GO:0006200	ATP catabolic process	1.07e-01	1.00e+00	3.157	1	8	219
GO:0005730	nucleolus	1.20e-01	1.00e+00	1.682	2	41	1217
GO:0005925	focal adhesion	1.36e-01	1.00e+00	2.792	1	4	282
GO:0009986	cell surface	1.40e-01	1.00e+00	2.747	1	2	291
GO:0045892	negative regulation of transcription, DNA-templated	1.52e-01	1.00e+00	2.623	1	7	317
GO:0043066	negative regulation of apoptotic process	1.54e-01	1.00e+00	2.601	1	20	322
GO:0006366	transcription from RNA polymerase II promoter	1.63e-01	1.00e+00	2.518	1	6	341
GO:0044267	cellular protein metabolic process	1.68e-01	1.00e+00	2.472	1	5	352
GO:0042802	identical protein binding	1.69e-01	1.00e+00	2.464	1	7	354
GO:0045893	positive regulation of transcription, DNA-templated	1.79e-01	1.00e+00	2.373	1	10	377
GO:0070062	extracellular vesicular exosome	1.99e-01	1.00e+00	1.251	2	43	1641
GO:0005634	nucleus	2.08e-01	1.00e+00	0.852	3	67	3246
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.89e-01	1.00e+00	1.601	1	8	644
GO:0005615	extracellular space	2.92e-01	1.00e+00	1.585	1	8	651
GO:0005739	mitochondrion	2.95e-01	1.00e+00	1.567	1	11	659
GO:0005515	protein binding	3.57e-01	1.00e+00	0.507	3	76	4124
GO:0006351	transcription, DNA-templated	4.42e-01	1.00e+00	0.860	1	9	1076
GO:0005886	plasma membrane	6.35e-01	1.00e+00	0.131	1	11	1784
GO:0005737	cytoplasm	7.92e-01	1.00e+00	-0.431	1	50	2633

Wolf-ratios-Mammosphere-Adherent

reg-snw-2547

Statistics

Genes (5)

Interactions (4)

Related GO terms (139)