meta-reg-snw-2237

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-2023 wolf-screen-ratio-mammosphere-adherent 0.930 2.50e-15 2.74e-03 4.31e-02 28 26
reg-snw-2237 wolf-screen-ratio-mammosphere-adherent 0.894 6.72e-08 6.99e-04 1.55e-03 9 8
int-snw-1455 wolf-screen-ratio-mammosphere-adherent 0.994 6.85e-18 6.35e-04 1.46e-02 16 15
int-snw-10209 wolf-screen-ratio-mammosphere-adherent 0.936 1.51e-15 2.42e-03 3.95e-02 14 13
int-snw-2957 wolf-screen-ratio-mammosphere-adherent 0.941 9.03e-16 2.14e-03 3.61e-02 25 21
int-snw-1120 wolf-screen-ratio-mammosphere-adherent 0.934 1.80e-15 2.53e-03 4.08e-02 16 15
int-snw-811 wolf-screen-ratio-mammosphere-adherent 0.932 2.10e-15 2.63e-03 4.19e-02 24 22
int-snw-3838 wolf-screen-ratio-mammosphere-adherent 0.930 2.46e-15 2.73e-03 4.30e-02 10 8
int-snw-3305 wolf-screen-ratio-mammosphere-adherent 0.942 8.57e-16 2.11e-03 3.57e-02 23 22
int-snw-57761 wolf-screen-ratio-mammosphere-adherent 0.969 7.13e-17 1.14e-03 2.28e-02 16 14
wolf-screen-ratio-mammosphere-adherent-meta-reg-snw-2237 subnetwork

Genes (62)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 900.5330.815238Yes-
DDX18 8886 250.6601.013215Yes-
PSMA2 5683 1121.0931.106108Yes-
PHB2 11331 430.8290.956151Yes-
TP53 7157 230.4320.833665--
SMARCA4 6597 260.4160.941253--
CHKB 1120 12-0.1690.93442-Yes
LPIN3 64900 8-0.6250.99439-Yes
ATP6V1B2 526 530.8811.076278--
ADH5 128 160.6330.99443Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
CALR 811 38-0.4180.93279-Yes
PSMD2 5708 170.4630.961386Yes-
RSL24D1 51187 381.3001.02059Yes-
EIF2S2 8894 391.0750.940103Yes-
PCNA 5111 330.5530.974294Yes-
PSMD1 5707 860.8360.830118Yes-
IARS 3376 70.3990.936175Yes-
EEF2 1938 640.8901.043301Yes-
RPS11 6205 620.9931.113175Yes-
EIF1 10209 7-0.2150.93664--
EFTUD2 9343 930.8830.956108Yes-
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
FBL 2091 420.8390.95679Yes-
HSPD1 3329 700.9131.035325Yes-
ENO1 2023 28-0.0780.930180--
KPNB1 3837 170.6131.017296Yes-
FEN1 2237 100.0140.89489--
ITK 3702 150.6020.95039Yes-
CSNK1G2 1455 8-0.0840.99490--
RBX1 9978 1151.1850.934148Yes-
POLA1 5422 170.5930.894114Yes-
RPL8 6132 240.7780.874234Yes-
PSMB7 5695 1180.9820.93490Yes-
HNRNPC 3183 1081.8120.973181Yes-
RPL6 6128 370.8441.113164Yes-
PSMA1 5682 1000.9960.878152Yes-
OGDH 4967 720.8470.802126Yes-
RPSA 3921 1201.3271.151152Yes-
RPS3A 6189 400.8351.069166Yes-
PGD 5226 891.2011.106152Yes-
HSPA1L 3305 34-0.4140.942125-Yes
TRIB3 57761 260.0970.96931--
ACO2 50 651.0001.076191Yes-
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD13 5719 560.8480.801114Yes-
GTF2A1 2957 260.2510.94152--
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
RPL14 9045 491.2501.113166Yes-
PSMB2 5690 1160.8770.956169Yes-
GSK3B 2932 220.4750.934319-Yes
ACTB 60 1341.1531.151610Yes-
KPNA2 3838 50.1760.930141--
ITGAV 3685 390.5560.94937--
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-
PSMC1 5700 510.8401.018137Yes-

Interactions (303)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
RPS11 6205 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMD2 5708 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastLow
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
ADH5 128 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
FEN1 2237 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
HSPA1L 3305 TP53 7157 pp -- int.I2D: MINT, MINT_Mouse;
int.Mint: MI:0915(physical association)
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD13 5719 pp -- int.I2D: YeastLow
PSMA3 5684 EIF1 10209 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Yeast
ACO2 50 OGDH 4967 pp -- int.I2D: YeastLow
PSMD2 5708 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
GSK3B 2932 TP53 7157 pp -- int.I2D: BIND, MINT, BCI, BioGrid, HPRD;
int.Mint: MI:0915(physical association), MI:0217(phosphorylation reaction);
int.HPRD: in vitro, in vivo
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
GSK3B 2932 LPIN3 64900 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
CAD 790 IARS 3376 pp -- int.I2D: YeastMedium
ACTB 60 GTF2A1 2957 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
KPNB1 3837 TP53 7157 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vivo
KPNA2 3838 EIF2S2 8894 pd > reg.ITFP.txt: no annot
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
ACTB 60 KPNB1 3837 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD2 5708 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMD1 5707 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMC1 5700 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
ATP6V1B2 526 OGDH 4967 pp -- int.I2D: IntAct_Yeast
CLTC 1213 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
RPL6 6128 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
IARS 3376 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
KPNA2 3838 SMARCA4 6597 pp -- int.I2D: BioGrid
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
IARS 3376 EIF1 10209 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
OGDH 4967 PSMD2 5708 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD1 5707 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
RPA2 6118 TP53 7157 pp -- int.Transfac: -
TP53 7157 EIF2S2 8894 pp -- int.Intact: MI:0915(physical association);
int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMD2 5708 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
RPL6 6128 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
CALR 811 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
GTF2A1 2957 SMARCA4 6597 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 PHB2 11331 pp -- int.I2D: IntAct_Yeast
KPNB1 3837 DDX18 8886 pp -- int.I2D: Krogan_NonCore, YeastLow
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
KPNB1 3837 RUVBL1 8607 pp -- int.I2D: BioGrid
CSNK1G2 1455 PSMA3 5684 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
ADH5 128 TP53 7157 pp -- int.I2D: BioGrid
PSMC1 5700 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
CALR 811 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
ACTB 60 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMD2 5708 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastLow, BioGrid
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
HSPA1L 3305 RUVBL1 8607 pp -- int.I2D: BioGrid
RPS3A 6189 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 TP53 7157 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
GSK3B 2932 TUBG1 7283 pp -- int.I2D: MINT
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
FEN1 2237 PSMD11 5717 pd < reg.ITFP.txt: no annot
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RPS3A 6189 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
CSNK1G2 1455 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
ATP6V1B2 526 CHKB 1120 pp -- int.I2D: IntAct_Yeast
EEF2 1938 TP53 7157 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CHKB 1120 PSMD3 5709 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
CHKB 1120 GSK3B 2932 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
OGDH 4967 PSMD13 5719 pp -- int.I2D: YeastLow
OGDH 4967 PSMD6 9861 pp -- int.I2D: YeastLow
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPSA 3921 PHB2 11331 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
FEN1 2237 GSK3B 2932 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
RPS3A 6189 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
OGDH 4967 RPL8 6132 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 DDX18 8886 pp -- int.I2D: YeastLow
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPL8 6132 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
RUVBL1 8607 DDX18 8886 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RPL8 6132 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
ENO1 2023 PCNA 5111 pp -- int.I2D: MINT, BioGrid;
int.Mint: MI:0407(direct interaction), MI:0915(physical association)
KPNB1 3837 PSMA2 5683 pp -- int.I2D: Krogan_NonCore, YeastLow
ACTB 60 ENO1 2023 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
HNRNPC 3183 TP53 7157 pd < reg.ITFP.txt: no annot
PSMD2 5708 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 FBL 2091 pp -- int.I2D: MINT
ADH5 128 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
CAD 790 KPNB1 3837 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMC1 5700 PSMD1 5707 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, Krogan_Core, MINT_Yeast
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
ACO2 50 PSMD2 5708 pp -- int.I2D: YeastLow
HNRNPC 3183 SMARCA4 6597 pp -- int.I2D: BioGrid
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
RPL8 6132 DDX18 8886 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PHB2 11331 pp -- int.I2D: IntAct_Yeast
CALR 811 SMARCA4 6597 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
OGDH 4967 DDX18 8886 pp -- int.I2D: YeastLow
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
CAD 790 LPIN3 64900 pp -- int.I2D: IntAct_Yeast
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
ACO2 50 PSMC1 5700 pp -- int.I2D: YeastLow
PSMC1 5700 RUVBL2 10856 pp -- int.I2D: YeastLow
PCNA 5111 TP53 7157 pd < reg.TRANSFAC.txt: no annot
PSMD13 5719 RUVBL2 10856 pp -- int.I2D: YeastHigh
PSMD2 5708 RPL6 6128 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
RPL8 6132 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
CLTC 1213 KPNB1 3837 pp -- int.Intact: MI:0914(association)
ACO2 50 KPNB1 3837 pp -- int.I2D: IntAct_Yeast
RPSA 3921 TRIB3 57761 pp -- int.I2D: BioGrid
PSMA2 5683 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 RPL8 6132 pp -- int.I2D: BioGrid_Yeast
PCNA 5111 SMARCA4 6597 pp -- int.I2D: BioGrid
FBL 2091 RUVBL1 8607 pp -- int.I2D: BioGrid
ACTB 60 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
RPL6 6128 RPL8 6132 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMC1 5700 PSMD2 5708 pp -- int.Intact: MI:0915(physical association), MI:0407(direct interaction), MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, Krogan_Core, MINT_Worm, MINT_Yeast, Tarassov_PCA, VidalHuman_core, HPRD, IntAct_Worm, YeastLow;
int.HPRD: in vitro
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
PSMD2 5708 RAN 5901 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
POLA1 5422 TP53 7157 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vivo
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
HSPD1 3329 TP53 7157 pp -- int.Intact: MI:0914(association)
RPL8 6132 EIF1 10209 pp -- int.I2D: YeastMedium
KPNA2 3838 TP53 7157 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
ACTB 60 RPL6 6128 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD2 5708 pp -- int.I2D: BioGrid, BioGrid_Yeast
FEN1 2237 KPNA2 3838 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
KPNA2 3838 RAN 5901 pd > reg.ITFP.txt: no annot
RPL6 6128 DDX18 8886 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
IARS 3376 PHB2 11331 pp -- int.Proteinpedia: Mass spectrometry
PSMC1 5700 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ITK 3702 KPNA2 3838 pp -- int.I2D: BioGrid, HPRD, BIND;
int.HPRD: in vitro, in vivo
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 DDX18 8886 pp -- int.I2D: YeastLow
PSMA3 5684 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 TRIB3 57761 pp -- int.I2D: BioGrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
ENO1 2023 TP53 7157 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
KPNA2 3838 PCNA 5111 pd > reg.ITFP.txt: no annot
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
KPNB1 3837 PSMA1 5682 pp -- int.I2D: YeastLow
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
DDX18 8886 RSL24D1 51187 pp -- int.I2D: YeastLow, BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
ATP6V1B2 526 IARS 3376 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
CALR 811 ITGAV 3685 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro, in vivo
FBL 2091 RUVBL2 10856 pd < reg.ITFP.txt: no annot
FBL 2091 RUVBL2 10856 pp -- int.I2D: BioGrid
RPSA 3921 PCNA 5111 pp -- int.I2D: MINT, BioGrid;
int.Mint: MI:0915(physical association)
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 PSMD13 5719 pd < reg.ITFP.txt: no annot
EEF2 1938 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
CAD 790 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PCNA 5111 RUVBL2 10856 pp -- int.I2D: BioGrid
KPNA2 3838 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
IARS 3376 PGD 5226 pp -- int.I2D: YeastLow
SMARCA4 6597 TP53 7157 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct, BCI, HPRD;
int.Transfac: -;
int.Ravasi: -;
int.HPRD: in vitro, in vivo
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
ACO2 50 RUVBL1 8607 pp -- int.I2D: YeastLow
FEN1 2237 POLA1 5422 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSPA1L 3305 PSMA3 5684 pp -- int.I2D: BioGrid
ENO1 2023 KPNA2 3838 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
FBL 2091 RPL8 6132 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 LPIN3 64900 pp -- int.I2D: IntAct_Yeast
KPNB1 3837 PSMA3 5684 pp -- int.I2D: YeastLow
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
HSPA1L 3305 RUVBL2 10856 pp -- int.I2D: BioGrid
OGDH 4967 RPL6 6128 pp -- int.I2D: IntAct_Yeast
KPNB1 3837 KPNA2 3838 pp -- int.I2D: BioGrid, BIND_Mouse, IntAct_Fly, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro, yeast 2-hybrid;
int.DIP: MI:0407(direct interaction)
GSK3B 2932 EFTUD2 9343 pp -- int.I2D: BioGrid, MINT;
int.Mint: MI:0915(physical association)
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
FEN1 2237 PCNA 5111 pp -- int.Intact: MI:0915(physical association), MI:0403(colocalization);
int.I2D: BioGrid, BIND, BIND_Yeast, IntAct, IntAct_Yeast, Yu_GoldStd, BCI, BioGrid_Yeast, HPRD, Krogan_Core, MINT_Yeast, YeastLow;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
HSPD1 3329 OGDH 4967 pp -- int.I2D: YeastLow
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
OGDH 4967 PSMC1 5700 pp -- int.I2D: YeastLow
PSMD2 5708 RBX1 9978 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
HNRNPC 3183 KPNA2 3838 pp -- int.Intact: MI:0915(physical association)
PSMA1 5682 PSMC1 5700 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
PSMD13 5719 EIF1 10209 pp -- int.I2D: IntAct_Yeast, BioGrid_Yeast, BIND_Yeast
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
CAD 790 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
IARS 3376 PSMD3 5709 pp -- int.I2D: YeastLow
PSMD2 5708 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastLow, BioGrid, Krogan_Core
PSMD2 5708 EIF1 10209 pp -- int.I2D: IntAct_Yeast, BioGrid_Yeast, BIND_Yeast
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
SMARCA4 6597 RUVBL2 10856 pp -- int.I2D: YeastLow
EIF2S2 8894 EIF1 10209 pp -- int.I2D: BioGrid_Yeast
IARS 3376 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSPD1 3329 POLA1 5422 pp -- int.I2D: YeastLow
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
ACTB 60 SMARCA4 6597 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct, BCI, HPRD;
int.HPRD: in vitro, in vivo
KPNB1 3837 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PSMC1 5700 RUVBL1 8607 pp -- int.I2D: YeastLow
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2 526 PHB2 11331 pp -- int.I2D: IntAct_Yeast
KPNB1 3837 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, MGI, MIPS, BioGrid, BIND, BIND_Mouse, HPRD, INTEROLOG, YeastLow;
int.HPRD: in vitro
PSMD2 5708 RUVBL2 10856 pp -- int.I2D: YeastLow, IntAct_Yeast
PGD 5226 DDX18 8886 pp -- int.I2D: YeastLow
KPNB1 3837 RUVBL2 10856 pp -- int.I2D: BioGrid
PSMD2 5708 RUVBL1 8607 pp -- int.I2D: YeastLow
RPS11 6205 DDX18 8886 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACO2 50 DDX18 8886 pp -- int.I2D: YeastLow
ACTB 60 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RUVBL2 10856 PHB2 11331 pd > reg.ITFP.txt: no annot
RUVBL2 10856 PHB2 11331 pp -- int.I2D: IntAct_Yeast
CSNK1G2 1455 LPIN3 64900 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CAD 790 SMARCA4 6597 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
RPL6 6128 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
PSMC1 5700 PHB2 11331 pp -- int.I2D: BioGrid_Yeast
ENO1 2023 PSMA3 5684 pp -- int.I2D: BioGrid
PSMD2 5708 PHB2 11331 pp -- int.I2D: IntAct_Yeast

Related GO terms (841)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016032viral process1.24e-222.02e-183.6642655540
GO:0005829cytosol3.72e-216.06e-172.143431252562
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent8.42e-211.37e-165.658142373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.89e-203.09e-165.581142377
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.27e-192.07e-155.718132265
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.27e-192.07e-155.718132465
GO:0016071mRNA metabolic process1.50e-192.45e-154.4091834223
GO:0006521regulation of cellular amino acid metabolic process3.17e-195.17e-155.981122150
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.61e-195.89e-155.611132470
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.74e-196.11e-155.293142394
GO:0010467gene expression4.72e-197.70e-153.2982558669
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.87e-191.28e-145.531132474
GO:0016070RNA metabolic process9.52e-191.55e-144.2621834247
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.96e-183.19e-145.437132579
GO:0000502proteasome complex2.28e-183.72e-145.767122258
GO:0000082G1/S transition of mitotic cell cycle8.88e-181.45e-134.7181533150
GO:0005654nucleoplasm3.85e-176.28e-132.75128831095
GO:0016020membrane1.28e-162.08e-122.31533801746
GO:0042981regulation of apoptotic process3.62e-165.91e-124.6091426151
GO:0000278mitotic cell cycle4.40e-157.18e-113.5741852398
GO:0000209protein polyubiquitination1.49e-142.43e-104.7671221116
GO:0034641cellular nitrogen compound metabolic process9.63e-141.57e-094.2731325177
GO:0070062extracellular vesicular exosome1.15e-131.88e-091.87335982516
GO:0022624proteasome accessory complex1.52e-132.48e-096.7607917
GO:0005838proteasome regulatory particle2.13e-123.47e-087.0406712
GO:0043066negative regulation of apoptotic process4.09e-126.67e-083.2821630433
GO:0044281small molecule metabolic process1.18e-101.93e-062.22523571295
GO:0044822poly(A) RNA binding1.85e-103.02e-062.35821501078
GO:0005515protein binding4.59e-097.49e-050.983461726127
GO:0005839proteasome core complex5.53e-099.03e-056.19251118
GO:0004298threonine-type endopeptidase activity9.96e-091.63e-046.04051120
GO:0019058viral life cycle1.17e-081.91e-044.195810115
GO:0005730nucleolus1.97e-083.21e-041.84623701684
GO:0006915apoptotic process2.17e-083.55e-042.6901434571
GO:0006413translational initiation3.26e-085.33e-044.007812131
GO:0006414translational elongation5.91e-089.65e-044.30871193
GO:0005634nucleus2.15e-073.51e-031.051381314828
GO:0019083viral transcription6.10e-079.95e-034.2856881
GO:0006415translational termination9.32e-071.52e-024.1826887
GO:0016363nuclear matrix1.30e-062.12e-024.10261192
GO:0032201telomere maintenance via semi-conservative replication1.31e-062.14e-025.5814722
GO:0000722telomere maintenance via recombination2.65e-064.33e-025.3404726
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.66e-064.35e-023.92568104
GO:0006412translation2.84e-064.63e-023.164815235
GO:0019773proteasome core complex, alpha-subunit complex2.88e-064.71e-026.625358
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4.55e-067.42e-023.792610114
GO:0030529ribonucleoprotein complex4.55e-067.42e-023.79268114
GO:0006271DNA strand elongation involved in DNA replication5.50e-068.98e-025.0864931
GO:0005524ATP binding7.63e-061.25e-011.72517461354
GO:0006284base-excision repair1.41e-052.29e-014.7554739
GO:0006272leading strand elongation1.42e-052.32e-018.040222
GO:0030234enzyme regulator activity1.45e-052.37e-015.9253313
GO:0003735structural constituent of ribosome1.54e-052.52e-013.48668141
GO:0044267cellular protein metabolic process1.57e-052.56e-012.4111024495
GO:0043234protein complex1.70e-052.77e-012.811817300
GO:0035267NuA4 histone acetyltransferase complex1.84e-053.01e-015.8183414
GO:0042176regulation of protein catabolic process2.82e-054.61e-015.6253316
GO:0001649osteoblast differentiation2.99e-054.88e-013.7925695
GO:0003684damaged DNA binding4.13e-056.74e-014.36841151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.18e-058.45e-014.2854554
GO:0002039p53 binding5.57e-059.09e-014.2594755
GO:0003723RNA binding5.62e-059.18e-012.569819355
GO:0031625ubiquitin protein ligase binding6.10e-059.95e-013.133613180
GO:0006281DNA repair6.16e-051.00e+002.803722264
GO:0051087chaperone binding7.35e-051.00e+004.1584659
GO:0000723telomere maintenance7.35e-051.00e+004.1584859
GO:0005925focal adhesion7.51e-051.00e+002.509818370
GO:0006297nucleotide-excision repair, DNA gap filling7.64e-051.00e+005.1663522
GO:0043044ATP-dependent chromatin remodeling8.76e-051.00e+005.1023423
GO:0006611protein export from nucleus1.13e-041.00e+004.9813425
GO:0005844polysome1.13e-041.00e+004.9813425
GO:0031492nucleosomal DNA binding1.60e-041.00e+004.8183428
GO:0019901protein kinase binding2.04e-041.00e+002.526721320
GO:0030957Tat protein binding2.11e-041.00e+006.455246
GO:0016887ATPase activity2.15e-041.00e+003.19257144
GO:0000812Swr1 complex3.92e-041.00e+006.040238
GO:0070182DNA polymerase binding3.92e-041.00e+006.040228
GO:0050681androgen receptor binding4.01e-041.00e+004.3773438
GO:0032092positive regulation of protein binding4.33e-041.00e+004.3403339
GO:0022627cytosolic small ribosomal subunit4.33e-041.00e+004.3403339
GO:0051082unfolded protein binding4.64e-041.00e+003.4704695
GO:0006983ER overload response5.02e-041.00e+005.870229
GO:0008139nuclear localization sequence binding5.02e-041.00e+005.870229
GO:0031571mitotic G1 DNA damage checkpoint7.64e-041.00e+005.5812311
GO:0022625cytosolic large ribosomal subunit8.49e-041.00e+004.0103549
GO:0019985translesion synthesis9.14e-041.00e+005.4552212
GO:0043968histone H2A acetylation9.14e-041.00e+005.4552312
GO:0006200ATP catabolic process1.00e-031.00e+002.382614303
GO:0006646phosphatidylethanolamine biosynthetic process1.08e-031.00e+005.3402213
GO:0006607NLS-bearing protein import into nucleus1.25e-031.00e+005.2332214
GO:0031011Ino80 complex1.25e-031.00e+005.2332314
GO:0042026protein refolding1.44e-031.00e+005.1332215
GO:0000790nuclear chromatin1.63e-031.00e+002.98547133
GO:0006302double-strand break repair1.68e-031.00e+003.6713862
GO:0005737cytoplasm1.71e-031.00e+000.78426983976
GO:0075733intracellular transport of virus1.86e-031.00e+004.9532217
GO:0005759mitochondrial matrix1.90e-031.00e+002.498512233
GO:0017025TBP-class protein binding2.09e-031.00e+004.8702218
GO:0006289nucleotide-excision repair2.29e-031.00e+003.51731269
GO:0006259DNA metabolic process2.33e-031.00e+004.7922319
GO:0003678DNA helicase activity2.33e-031.00e+004.7922319
GO:0005719nuclear euchromatin2.58e-031.00e+004.7182220
GO:0006298mismatch repair2.58e-031.00e+004.7182620
GO:0000785chromatin2.69e-031.00e+003.4353573
GO:0033574response to testosterone3.12e-031.00e+004.5812222
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle3.12e-031.00e+004.5812322
GO:0006656phosphatidylcholine biosynthetic process3.12e-031.00e+004.5812322
GO:0036464cytoplasmic ribonucleoprotein granule3.12e-031.00e+004.5812422
GO:0008135translation factor activity, nucleic acid binding3.71e-031.00e+004.4552424
GO:0000060protein import into nucleus, translocation3.71e-031.00e+004.4552424
GO:0002842positive regulation of T cell mediated immune response to tumor cell3.80e-031.00e+008.040111
GO:0002502peptide antigen assembly with MHC class I protein complex3.80e-031.00e+008.040111
GO:0018467formaldehyde dehydrogenase activity3.80e-031.00e+008.040111
GO:0035867alphav-beta3 integrin-IGF-1-IGF1R complex3.80e-031.00e+008.040111
GO:0008309double-stranded DNA exodeoxyribonuclease activity3.80e-031.00e+008.040111
GO:0032077positive regulation of deoxyribonuclease activity3.80e-031.00e+008.040111
GO:0000701purine-specific mismatch base pair DNA N-glycosylase activity3.80e-031.00e+008.040111
GO:0048291isotype switching to IgG isotypes3.80e-031.00e+008.040111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity3.80e-031.00e+008.040111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity3.80e-031.00e+008.040111
GO:0052066entry of symbiont into host cell by promotion of host phagocytosis3.80e-031.00e+008.040111
GO:0019521D-gluconate metabolic process3.80e-031.00e+008.040111
GO:0016074snoRNA metabolic process3.80e-031.00e+008.040111
GO:0002368B cell cytokine production3.80e-031.00e+008.040111
GO:0070335aspartate binding3.80e-031.00e+008.040111
GO:1990259histone-glutamine methyltransferase activity3.80e-031.00e+008.040111
GO:0043626PCNA complex3.80e-031.00e+008.040111
GO:0051903S-(hydroxymethyl)glutathione dehydrogenase activity3.80e-031.00e+008.040111
GO:2000425regulation of apoptotic cell clearance3.80e-031.00e+008.040111
GO:1990258histone glutamine methylation3.80e-031.00e+008.040111
GO:0004151dihydroorotase activity3.80e-031.00e+008.040111
GO:0004070aspartate carbamoyltransferase activity3.80e-031.00e+008.040111
GO:2000536negative regulation of entry of bacterium into host cell3.80e-031.00e+008.040111
GO:0047485protein N-terminus binding4.27e-031.00e+003.1993486
GO:0019843rRNA binding4.69e-031.00e+004.2852327
GO:0071339MLL1 complex4.69e-031.00e+004.2852327
GO:0043967histone H4 acetylation5.04e-031.00e+004.2332328
GO:0042470melanosome5.16e-031.00e+003.10231092
GO:0045892negative regulation of transcription, DNA-templated5.35e-031.00e+001.897614424
GO:0006099tricarboxylic acid cycle5.40e-031.00e+004.1822329
GO:0034644cellular response to UV6.54e-031.00e+004.0402532
GO:0033572transferrin transport6.54e-031.00e+004.0402632
GO:0030971receptor tyrosine kinase binding6.95e-031.00e+003.9962233
GO:0001085RNA polymerase II transcription factor binding7.37e-031.00e+003.9532234
GO:0003924GTPase activity7.39e-031.00e+002.37549203
GO:0097252oligodendrocyte apoptotic process7.58e-031.00e+007.040112
GO:0045252oxoglutarate dehydrogenase complex7.58e-031.00e+007.040122
GO:0034686integrin alphav-beta8 complex7.58e-031.00e+007.040112
GO:0035887aortic smooth muscle cell differentiation7.58e-031.00e+007.040112
GO:0003994aconitate hydratase activity7.58e-031.00e+007.040112
GO:0006407rRNA export from nucleus7.58e-031.00e+007.040112
GO:0042824MHC class I peptide loading complex7.58e-031.00e+007.040112
GO:0001846opsonin binding7.58e-031.00e+007.040112
GO:1990430extracellular matrix protein binding7.58e-031.00e+007.040112
GO:0061034olfactory bulb mitral cell layer development7.58e-031.00e+007.040112
GO:0071109superior temporal gyrus development7.58e-031.00e+007.040112
GO:0033144negative regulation of intracellular steroid hormone receptor signaling pathway7.58e-031.00e+007.040112
GO:0050748negative regulation of lipoprotein metabolic process7.58e-031.00e+007.040112
GO:2000077negative regulation of type B pancreatic cell development7.58e-031.00e+007.040112
GO:0090343positive regulation of cell aging7.58e-031.00e+007.040112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)7.58e-031.00e+007.040112
GO:0019322pentose biosynthetic process7.58e-031.00e+007.040112
GO:0034683integrin alphav-beta3 complex7.58e-031.00e+007.040112
GO:0030337DNA polymerase processivity factor activity7.58e-031.00e+007.040112
GO:00515383 iron, 4 sulfur cluster binding7.58e-031.00e+007.040112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process7.58e-031.00e+007.040122
GO:1901525negative regulation of macromitophagy7.58e-031.00e+007.040112
GO:0006428isoleucyl-tRNA aminoacylation7.58e-031.00e+007.040112
GO:0002176male germ cell proliferation7.58e-031.00e+007.040112
GO:0004103choline kinase activity7.58e-031.00e+007.040112
GO:0046294formaldehyde catabolic process7.58e-031.00e+007.040112
GO:0070557PCNA-p21 complex7.58e-031.00e+007.040112
GO:0032633interleukin-4 production7.58e-031.00e+007.040112
GO:0004822isoleucine-tRNA ligase activity7.58e-031.00e+007.040112
GO:0005055laminin receptor activity7.58e-031.00e+007.040112
GO:0034684integrin alphav-beta5 complex7.58e-031.00e+007.040112
GO:0001865NK T cell differentiation7.58e-031.00e+007.040112
GO:0007127meiosis I7.58e-031.00e+007.040112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis7.58e-031.00e+007.040122
GO:0070409carbamoyl phosphate biosynthetic process7.58e-031.00e+007.040112
GO:0042277peptide binding7.79e-031.00e+003.9112235
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand7.79e-031.00e+003.9112235
GO:0016301kinase activity8.68e-031.00e+003.8312337
GO:00515394 iron, 4 sulfur cluster binding8.68e-031.00e+003.8312337
GO:0030308negative regulation of cell growth9.09e-031.00e+002.80536113
GO:0005813centrosome9.24e-031.00e+001.957512339
GO:0006096glycolytic process9.61e-031.00e+003.7552439
GO:0021766hippocampus development9.61e-031.00e+003.7552439
GO:0006184GTP catabolic process9.74e-031.00e+002.25949220
GO:0032508DNA duplex unwinding1.11e-021.00e+003.6482442
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity1.14e-021.00e+006.455113
GO:0010424DNA methylation on cytosine within a CG sequence1.14e-021.00e+006.455113
GO:0014043negative regulation of neuron maturation1.14e-021.00e+006.455113
GO:0000320re-entry into mitotic cell cycle1.14e-021.00e+006.455113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity1.14e-021.00e+006.455113
GO:0045715negative regulation of low-density lipoprotein particle receptor biosynthetic process1.14e-021.00e+006.455113
GO:2000466negative regulation of glycogen (starch) synthase activity1.14e-021.00e+006.455113
GO:1900126negative regulation of hyaluronan biosynthetic process1.14e-021.00e+006.455113
GO:0006458'de novo' protein folding1.14e-021.00e+006.455113
GO:0035033histone deacetylase regulator activity1.14e-021.00e+006.455113
GO:0007403glial cell fate determination1.14e-021.00e+006.455113
GO:0002360T cell lineage commitment1.14e-021.00e+006.455113
GO:0009051pentose-phosphate shunt, oxidative branch1.14e-021.00e+006.455113
GO:0034103regulation of tissue remodeling1.14e-021.00e+006.455113
GO:0030135coated vesicle1.14e-021.00e+006.455113
GO:0005726perichromatin fibrils1.14e-021.00e+006.455113
GO:0044205'de novo' UMP biosynthetic process1.14e-021.00e+006.455113
GO:0009048dosage compensation by inactivation of X chromosome1.14e-021.00e+006.455113
GO:0018119peptidyl-cysteine S-nitrosylation1.14e-021.00e+006.455113
GO:0032139dinucleotide insertion or deletion binding1.14e-021.00e+006.455113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb1.14e-021.00e+006.455113
GO:0035794positive regulation of mitochondrial membrane permeability1.14e-021.00e+006.455113
GO:0006325chromatin organization1.14e-021.00e+002.68334123
GO:0071899negative regulation of estrogen receptor binding1.14e-021.00e+006.455113
GO:0051097negative regulation of helicase activity1.14e-021.00e+006.455113
GO:0005850eukaryotic translation initiation factor 2 complex1.14e-021.00e+006.455113
GO:0071733transcriptional activation by promoter-enhancer looping1.14e-021.00e+006.455113
GO:0044027hypermethylation of CpG island1.14e-021.00e+006.455113
GO:0001832blastocyst growth1.14e-021.00e+006.455113
GO:0055106ubiquitin-protein transferase regulator activity1.14e-021.00e+006.455113
GO:0000056ribosomal small subunit export from nucleus1.14e-021.00e+006.455113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process1.14e-021.00e+006.455113
GO:0071439clathrin complex1.14e-021.00e+006.455113
GO:0007067mitotic nuclear division1.15e-021.00e+002.188413231
GO:0042110T cell activation1.16e-021.00e+003.6142343
GO:0006260DNA replication1.19e-021.00e+002.659312125
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.21e-021.00e+003.5812244
GO:0015030Cajal body1.27e-021.00e+003.5482245
GO:0006283transcription-coupled nucleotide-excision repair1.32e-021.00e+003.5172846
GO:0009615response to virus1.38e-021.00e+002.58136132
GO:0003743translation initiation factor activity1.49e-021.00e+003.4262449
GO:003068690S preribosome1.51e-021.00e+006.040114
GO:0004305ethanolamine kinase activity1.51e-021.00e+006.040114
GO:0043137DNA replication, removal of RNA primer1.51e-021.00e+006.040114
GO:0019788NEDD8 ligase activity1.51e-021.00e+006.040114
GO:0051409response to nitrosative stress1.51e-021.00e+006.040114
GO:0001652granular component1.51e-021.00e+006.040114
GO:0031428box C/D snoRNP complex1.51e-021.00e+006.040114
GO:0006068ethanol catabolic process1.51e-021.00e+006.040114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.51e-021.00e+006.040114
GO:0002326B cell lineage commitment1.51e-021.00e+006.040114
GO:0051534negative regulation of NFAT protein import into nucleus1.51e-021.00e+006.040114
GO:0006273lagging strand elongation1.51e-021.00e+006.040114
GO:0003896DNA primase activity1.51e-021.00e+006.040124
GO:2000510positive regulation of dendritic cell chemotaxis1.51e-021.00e+006.040114
GO:0071782endoplasmic reticulum tubular network1.51e-021.00e+006.040114
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.51e-021.00e+006.040114
GO:0000212meiotic spindle organization1.51e-021.00e+006.040114
GO:0005658alpha DNA polymerase:primase complex1.51e-021.00e+006.040114
GO:0032051clathrin light chain binding1.51e-021.00e+006.040114
GO:0000015phosphopyruvate hydratase complex1.51e-021.00e+006.040124
GO:0004634phosphopyruvate hydratase activity1.51e-021.00e+006.040124
GO:0090403oxidative stress-induced premature senescence1.51e-021.00e+006.040114
GO:0060318definitive erythrocyte differentiation1.51e-021.00e+006.040114
GO:0006104succinyl-CoA metabolic process1.51e-021.00e+006.040114
GO:0006543glutamine catabolic process1.51e-021.00e+006.040114
GO:0001835blastocyst hatching1.51e-021.00e+006.040124
GO:0031467Cul7-RING ubiquitin ligase complex1.51e-021.00e+006.040114
GO:0000055ribosomal large subunit export from nucleus1.51e-021.00e+006.040114
GO:0032369negative regulation of lipid transport1.51e-021.00e+006.040114
GO:0006610ribosomal protein import into nucleus1.51e-021.00e+006.040114
GO:0051208sequestering of calcium ion1.51e-021.00e+006.040114
GO:1903077negative regulation of protein localization to plasma membrane1.51e-021.00e+006.040114
GO:0001948glycoprotein binding1.55e-021.00e+003.3962350
GO:0035690cellular response to drug1.55e-021.00e+003.3962250
GO:0006091generation of precursor metabolites and energy1.61e-021.00e+003.3682351
GO:0040008regulation of growth1.61e-021.00e+003.3682351
GO:0006986response to unfolded protein1.61e-021.00e+003.3682251
GO:0003725double-stranded RNA binding1.79e-021.00e+003.2852654
GO:0005672transcription factor TFIIA complex1.89e-021.00e+005.718115
GO:0001882nucleoside binding1.89e-021.00e+005.718115
GO:2000001regulation of DNA damage checkpoint1.89e-021.00e+005.718115
GO:0048562embryonic organ morphogenesis1.89e-021.00e+005.718115
GO:0006269DNA replication, synthesis of RNA primer1.89e-021.00e+005.718125
GO:0043248proteasome assembly1.89e-021.00e+005.718115
GO:0036016cellular response to interleukin-31.89e-021.00e+005.718115
GO:0004022alcohol dehydrogenase (NAD) activity1.89e-021.00e+005.718115
GO:0030891VCB complex1.89e-021.00e+005.718125
GO:00171085'-flap endonuclease activity1.89e-021.00e+005.718115
GO:0005827polar microtubule1.89e-021.00e+005.718115
GO:0043405regulation of MAP kinase activity1.89e-021.00e+005.718115
GO:0006734NADH metabolic process1.89e-021.00e+005.718115
GO:0004523RNA-DNA hybrid ribonuclease activity1.89e-021.00e+005.718115
GO:0003407neural retina development1.89e-021.00e+005.718115
GO:0051414response to cortisol1.89e-021.00e+005.718115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.89e-021.00e+005.718125
GO:0038027apolipoprotein A-I-mediated signaling pathway1.89e-021.00e+005.718115
GO:0097371MDM2/MDM4 family protein binding1.89e-021.00e+005.718115
GO:0031461cullin-RING ubiquitin ligase complex1.89e-021.00e+005.718115
GO:0071169establishment of protein localization to chromatin1.89e-021.00e+005.718115
GO:0046696lipopolysaccharide receptor complex1.89e-021.00e+005.718115
GO:2000738positive regulation of stem cell differentiation1.89e-021.00e+005.718115
GO:0006102isocitrate metabolic process1.89e-021.00e+005.718115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.89e-021.00e+005.718115
GO:0000730DNA recombinase assembly1.89e-021.00e+005.718135
GO:0048730epidermis morphogenesis1.89e-021.00e+005.718115
GO:0030976thiamine pyrophosphate binding1.89e-021.00e+005.718115
GO:0006457protein folding1.90e-021.00e+002.40638149
GO:0008565protein transporter activity1.98e-021.00e+003.2072257
GO:0005643nuclear pore2.11e-021.00e+003.1582459
GO:0000018regulation of DNA recombination2.26e-021.00e+005.455116
GO:0003688DNA replication origin binding2.26e-021.00e+005.455116
GO:0005663DNA replication factor C complex2.26e-021.00e+005.455116
GO:0010666positive regulation of cardiac muscle cell apoptotic process2.26e-021.00e+005.455116
GO:1902108regulation of mitochondrial membrane permeability involved in apoptotic process2.26e-021.00e+005.455116
GO:0002309T cell proliferation involved in immune response2.26e-021.00e+005.455116
GO:0006101citrate metabolic process2.26e-021.00e+005.455116
GO:0030118clathrin coat2.26e-021.00e+005.455116
GO:0021695cerebellar cortex development2.26e-021.00e+005.455116
GO:0046134pyrimidine nucleoside biosynthetic process2.26e-021.00e+005.455116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex2.26e-021.00e+005.455116
GO:0070245positive regulation of thymocyte apoptotic process2.26e-021.00e+005.455116
GO:0050764regulation of phagocytosis2.26e-021.00e+005.455116
GO:0040020regulation of meiosis2.26e-021.00e+005.455116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis2.26e-021.00e+005.455116
GO:0010614negative regulation of cardiac muscle hypertrophy2.26e-021.00e+005.455116
GO:0002181cytoplasmic translation2.26e-021.00e+005.455116
GO:0030130clathrin coat of trans-Golgi network vesicle2.26e-021.00e+005.455116
GO:0060744mammary gland branching involved in thelarche2.26e-021.00e+005.455116
GO:0006346methylation-dependent chromatin silencing2.26e-021.00e+005.455116
GO:0021860pyramidal neuron development2.26e-021.00e+005.455116
GO:0033993response to lipid2.26e-021.00e+005.455126
GO:0031466Cul5-RING ubiquitin ligase complex2.26e-021.00e+005.455116
GO:0050774negative regulation of dendrite morphogenesis2.26e-021.00e+005.455116
GO:0007406negative regulation of neuroblast proliferation2.26e-021.00e+005.455116
GO:0032405MutLalpha complex binding2.26e-021.00e+005.455126
GO:0019899enzyme binding2.38e-021.00e+001.870411288
GO:0019903protein phosphatase binding2.39e-021.00e+003.0632463
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.60e-021.00e+002.23335168
GO:0042921glucocorticoid receptor signaling pathway2.63e-021.00e+005.233117
GO:0001849complement component C1q binding2.63e-021.00e+005.233117
GO:0010888negative regulation of lipid storage2.63e-021.00e+005.233127
GO:0031462Cul2-RING ubiquitin ligase complex2.63e-021.00e+005.233127
GO:0031994insulin-like growth factor I binding2.63e-021.00e+005.233117
GO:0000028ribosomal small subunit assembly2.63e-021.00e+005.233117
GO:0002161aminoacyl-tRNA editing activity2.63e-021.00e+005.233127
GO:0006657CDP-choline pathway2.63e-021.00e+005.233117
GO:0033180proton-transporting V-type ATPase, V1 domain2.63e-021.00e+005.233127
GO:0030132clathrin coat of coated pit2.63e-021.00e+005.233117
GO:0031497chromatin assembly2.63e-021.00e+005.233117
GO:0000930gamma-tubulin complex2.63e-021.00e+005.233117
GO:0006310DNA recombination2.68e-021.00e+002.9742467
GO:0038095Fc-epsilon receptor signaling pathway2.72e-021.00e+002.20737171
GO:0006338chromatin remodeling2.75e-021.00e+002.9532468
GO:0003697single-stranded DNA binding2.83e-021.00e+002.9322969
GO:0000287magnesium ion binding2.85e-021.00e+002.18235174
GO:0000733DNA strand renaturation3.00e-021.00e+005.040118
GO:0006554lysine catabolic process3.00e-021.00e+005.040128
GO:0045116protein neddylation3.00e-021.00e+005.040128
GO:0043596nuclear replication fork3.00e-021.00e+005.040118
GO:0045719negative regulation of glycogen biosynthetic process3.00e-021.00e+005.040118
GO:0033018sarcoplasmic reticulum lumen3.00e-021.00e+005.040118
GO:0031464Cul4A-RING E3 ubiquitin ligase complex3.00e-021.00e+005.040128
GO:0070688MLL5-L complex3.00e-021.00e+005.040118
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway3.00e-021.00e+005.040118
GO:0035372protein localization to microtubule3.00e-021.00e+005.040118
GO:0003714transcription corepressor activity3.06e-021.00e+002.14137179
GO:0002020protease binding3.22e-021.00e+002.8312474
GO:0044183protein binding involved in protein folding3.37e-021.00e+004.870119
GO:00084095'-3' exonuclease activity3.37e-021.00e+004.870119
GO:0003016respiratory system process3.37e-021.00e+004.870119
GO:0031065positive regulation of histone deacetylation3.37e-021.00e+004.870119
GO:0045717negative regulation of fatty acid biosynthetic process3.37e-021.00e+004.870119
GO:0033690positive regulation of osteoblast proliferation3.37e-021.00e+004.870119
GO:0014075response to amine3.37e-021.00e+004.870119
GO:0008494translation activator activity3.37e-021.00e+004.870119
GO:0048156tau protein binding3.37e-021.00e+004.870119
GO:0032609interferon-gamma production3.37e-021.00e+004.870119
GO:0006228UTP biosynthetic process3.37e-021.00e+004.870119
GO:0031000response to caffeine3.37e-021.00e+004.870129
GO:0022417protein maturation by protein folding3.37e-021.00e+004.870119
GO:0046474glycerophospholipid biosynthetic process3.38e-021.00e+002.7922376
GO:0005525GTP binding3.59e-021.00e+001.683411328
GO:0071013catalytic step 2 spliceosome3.63e-021.00e+002.7362779
GO:0008283cell proliferation3.70e-021.00e+001.670412331
GO:0002199zona pellucida receptor complex3.74e-021.00e+004.7181110
GO:0043032positive regulation of macrophage activation3.74e-021.00e+004.7181110
GO:0090399replicative senescence3.74e-021.00e+004.7181110
GO:0008195phosphatidate phosphatase activity3.74e-021.00e+004.7181110
GO:0070307lens fiber cell development3.74e-021.00e+004.7181210
GO:0006069ethanol oxidation3.74e-021.00e+004.7181110
GO:0046902regulation of mitochondrial membrane permeability3.74e-021.00e+004.7181110
GO:0051604protein maturation3.74e-021.00e+004.7181110
GO:0006450regulation of translational fidelity3.74e-021.00e+004.7181210
GO:0010226response to lithium ion3.74e-021.00e+004.7181210
GO:0000731DNA synthesis involved in DNA repair3.74e-021.00e+004.7181110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway3.74e-021.00e+004.7181110
GO:0030877beta-catenin destruction complex3.74e-021.00e+004.7181210
GO:0051775response to redox state3.74e-021.00e+004.7181110
GO:0021756striatum development3.74e-021.00e+004.7181110
GO:0042802identical protein binding3.85e-021.00e+001.423518491
GO:0001889liver development3.88e-021.00e+002.6832382
GO:0005681spliceosomal complex3.97e-021.00e+002.6652383
GO:0032727positive regulation of interferon-alpha production4.10e-021.00e+004.5811111
GO:0048387negative regulation of retinoic acid receptor signaling pathway4.10e-021.00e+004.5811111
GO:0045120pronucleus4.10e-021.00e+004.5811111
GO:0006098pentose-phosphate shunt4.10e-021.00e+004.5811311
GO:0008340determination of adult lifespan4.10e-021.00e+004.5811111
GO:0010569regulation of double-strand break repair via homologous recombination4.10e-021.00e+004.5811111
GO:0071850mitotic cell cycle arrest4.10e-021.00e+004.5811111
GO:0043923positive regulation by host of viral transcription4.10e-021.00e+004.5811211
GO:0071564npBAF complex4.10e-021.00e+004.5811211
GO:0009650UV protection4.47e-021.00e+004.4551112
GO:00709353'-UTR-mediated mRNA stabilization4.47e-021.00e+004.4551212
GO:0021794thalamus development4.47e-021.00e+004.4551112
GO:0070266necroptotic process4.47e-021.00e+004.4551112
GO:0032461positive regulation of protein oligomerization4.47e-021.00e+004.4551112
GO:0009303rRNA transcription4.47e-021.00e+004.4551112
GO:0032886regulation of microtubule-based process4.47e-021.00e+004.4551412
GO:0034236protein kinase A catalytic subunit binding4.47e-021.00e+004.4551112
GO:0071565nBAF complex4.47e-021.00e+004.4551212
GO:0006275regulation of DNA replication4.47e-021.00e+004.4551212
GO:0050321tau-protein kinase activity4.47e-021.00e+004.4551112
GO:0050821protein stabilization4.69e-021.00e+002.5322291
GO:0016605PML body4.78e-021.00e+002.5172592
GO:0001530lipopolysaccharide binding4.83e-021.00e+004.3401213
GO:0046827positive regulation of protein export from nucleus4.83e-021.00e+004.3401213
GO:0042273ribosomal large subunit biogenesis4.83e-021.00e+004.3401413
GO:0010745negative regulation of macrophage derived foam cell differentiation4.83e-021.00e+004.3401213
GO:0060766negative regulation of androgen receptor signaling pathway4.83e-021.00e+004.3401113
GO:0005662DNA replication factor A complex4.83e-021.00e+004.3401313
GO:0000738DNA catabolic process, exonucleolytic4.83e-021.00e+004.3401213
GO:0008266poly(U) RNA binding4.83e-021.00e+004.3401113
GO:0051131chaperone-mediated protein complex assembly4.83e-021.00e+004.3401113
GO:0005200structural constituent of cytoskeleton4.87e-021.00e+002.5012793
GO:0006364rRNA processing5.16e-021.00e+002.4552596
GO:0031333negative regulation of protein complex assembly5.19e-021.00e+004.2331114
GO:0005504fatty acid binding5.19e-021.00e+004.2331114
GO:0043277apoptotic cell clearance5.19e-021.00e+004.2331114
GO:0048168regulation of neuronal synaptic plasticity5.19e-021.00e+004.2331114
GO:0030330DNA damage response, signal transduction by p53 class mediator5.19e-021.00e+004.2331114
GO:0071285cellular response to lithium ion5.19e-021.00e+004.2331214
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator5.19e-021.00e+004.2331214
GO:2000378negative regulation of reactive oxygen species metabolic process5.19e-021.00e+004.2331114
GO:0004527exonuclease activity5.19e-021.00e+004.2331114
GO:0007020microtubule nucleation5.19e-021.00e+004.2331114
GO:0031334positive regulation of protein complex assembly5.19e-021.00e+004.2331214
GO:0009651response to salt stress5.19e-021.00e+004.2331214
GO:0048568embryonic organ development5.19e-021.00e+004.2331114
GO:0005178integrin binding5.25e-021.00e+002.4402297
GO:0071456cellular response to hypoxia5.35e-021.00e+002.4262498
GO:0051443positive regulation of ubiquitin-protein transferase activity5.55e-021.00e+004.1331115
GO:0006349regulation of gene expression by genetic imprinting5.55e-021.00e+004.1331115
GO:0046961proton-transporting ATPase activity, rotational mechanism5.55e-021.00e+004.1331315
GO:0016514SWI/SNF complex5.55e-021.00e+004.1331315
GO:0060749mammary gland alveolus development5.55e-021.00e+004.1331115
GO:0035066positive regulation of histone acetylation5.55e-021.00e+004.1331115
GO:0050431transforming growth factor beta binding5.55e-021.00e+004.1331115
GO:0060347heart trabecula formation5.55e-021.00e+004.1331115
GO:0042562hormone binding5.91e-021.00e+004.0401116
GO:0030902hindbrain development5.91e-021.00e+004.0401116
GO:0050998nitric-oxide synthase binding5.91e-021.00e+004.0401116
GO:0007520myoblast fusion5.91e-021.00e+004.0401116
GO:0046034ATP metabolic process5.91e-021.00e+004.0401116
GO:0071682endocytic vesicle lumen5.91e-021.00e+004.0401116
GO:00061032-oxoglutarate metabolic process5.91e-021.00e+004.0401116
GO:00084083'-5' exonuclease activity5.91e-021.00e+004.0401216
GO:0031589cell-substrate adhesion5.91e-021.00e+004.0401116
GO:0003713transcription coactivator activity6.25e-021.00e+001.724310239
GO:0006337nucleosome disassembly6.27e-021.00e+003.9531417
GO:0042149cellular response to glucose starvation6.27e-021.00e+003.9531117
GO:0035255ionotropic glutamate receptor binding6.27e-021.00e+003.9531117
GO:0003746translation elongation factor activity6.27e-021.00e+003.9531317
GO:0031528microvillus membrane6.27e-021.00e+003.9531117
GO:0031258lamellipodium membrane6.27e-021.00e+003.9531217
GO:0070577lysine-acetylated histone binding6.27e-021.00e+003.9531117
GO:0031527filopodium membrane6.27e-021.00e+003.9531117
GO:0010243response to organonitrogen compound6.27e-021.00e+003.9531217
GO:0050919negative chemotaxis6.27e-021.00e+003.9531117
GO:0045777positive regulation of blood pressure6.27e-021.00e+003.9531117
GO:0006309apoptotic DNA fragmentation6.27e-021.00e+003.9531117
GO:0050870positive regulation of T cell activation6.27e-021.00e+003.9531117
GO:0046718viral entry into host cell6.62e-021.00e+003.8701118
GO:0071392cellular response to estradiol stimulus6.62e-021.00e+003.8701118
GO:0031122cytoplasmic microtubule organization6.62e-021.00e+003.8701218
GO:0035861site of double-strand break6.62e-021.00e+003.8701118
GO:0004004ATP-dependent RNA helicase activity6.62e-021.00e+003.8701218
GO:0010800positive regulation of peptidyl-threonine phosphorylation6.62e-021.00e+003.8701118
GO:0005657replication fork6.62e-021.00e+003.8701318
GO:0006541glutamine metabolic process6.62e-021.00e+003.8701118
GO:0070371ERK1 and ERK2 cascade6.62e-021.00e+003.8701118
GO:0051721protein phosphatase 2A binding6.62e-021.00e+003.8701118
GO:0006303double-strand break repair via nonhomologous end joining6.62e-021.00e+003.8701318
GO:0050840extracellular matrix binding6.98e-021.00e+003.7921119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process6.98e-021.00e+003.7921119
GO:0035035histone acetyltransferase binding6.98e-021.00e+003.7921119
GO:0071158positive regulation of cell cycle arrest6.98e-021.00e+003.7921119
GO:0032733positive regulation of interleukin-10 production6.98e-021.00e+003.7921119
GO:0007088regulation of mitosis6.98e-021.00e+003.7921119
GO:0055007cardiac muscle cell differentiation6.98e-021.00e+003.7921119
GO:0010165response to X-ray6.98e-021.00e+003.7921219
GO:0034113heterotypic cell-cell adhesion6.98e-021.00e+003.7921119
GO:0005819spindle6.98e-021.00e+002.20727114
GO:0048863stem cell differentiation6.98e-021.00e+003.7921119
GO:0031430M band6.98e-021.00e+003.7921119
GO:0030866cortical actin cytoskeleton organization6.98e-021.00e+003.7921119
GO:0048015phosphatidylinositol-mediated signaling7.08e-021.00e+002.19523115
GO:0072562blood microparticle7.19e-021.00e+002.18224116
GO:0005635nuclear envelope7.19e-021.00e+002.18226116
GO:0015078hydrogen ion transmembrane transporter activity7.33e-021.00e+003.7181320
GO:2000134negative regulation of G1/S transition of mitotic cell cycle7.33e-021.00e+003.7181220
GO:0090398cellular senescence7.33e-021.00e+003.7181120
GO:0002931response to ischemia7.33e-021.00e+003.7181120
GO:0005680anaphase-promoting complex7.33e-021.00e+003.7181420
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator7.33e-021.00e+003.7181120
GO:0044237cellular metabolic process7.41e-021.00e+002.15823118
GO:0007369gastrulation7.69e-021.00e+003.6481121
GO:0071364cellular response to epidermal growth factor stimulus7.69e-021.00e+003.6481121
GO:0001954positive regulation of cell-matrix adhesion7.69e-021.00e+003.6481121
GO:0008156negative regulation of DNA replication7.69e-021.00e+003.6481121
GO:0004860protein kinase inhibitor activity7.69e-021.00e+003.6481221
GO:0030010establishment of cell polarity7.69e-021.00e+003.6481221
GO:0000718nucleotide-excision repair, DNA damage removal7.69e-021.00e+003.6481521
GO:0005669transcription factor TFIID complex8.04e-021.00e+003.5811122
GO:0046686response to cadmium ion8.04e-021.00e+003.5811322
GO:0005790smooth endoplasmic reticulum8.04e-021.00e+003.5811122
GO:0000792heterochromatin8.04e-021.00e+003.5811222
GO:0090200positive regulation of release of cytochrome c from mitochondria8.04e-021.00e+003.5811122
GO:0030863cortical cytoskeleton8.04e-021.00e+003.5811122
GO:0006270DNA replication initiation8.04e-021.00e+003.5811522
GO:0007052mitotic spindle organization8.04e-021.00e+003.5811222
GO:0007219Notch signaling pathway8.18e-021.00e+002.07424125
GO:0007050cell cycle arrest8.29e-021.00e+002.06327126
GO:1900026positive regulation of substrate adhesion-dependent cell spreading8.39e-021.00e+003.5171223
GO:0031463Cul3-RING ubiquitin ligase complex8.39e-021.00e+003.5171223
GO:0043236laminin binding8.39e-021.00e+003.5171123
GO:0045787positive regulation of cell cycle8.39e-021.00e+003.5171123
GO:0008305integrin complex8.39e-021.00e+003.5171123
GO:0006513protein monoubiquitination8.39e-021.00e+003.5171123
GO:0005506iron ion binding8.40e-021.00e+002.05223127
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress8.74e-021.00e+003.4551124
GO:0001836release of cytochrome c from mitochondria8.74e-021.00e+003.4551224
GO:0048147negative regulation of fibroblast proliferation8.74e-021.00e+003.4551124
GO:0001105RNA polymerase II transcription coactivator activity8.74e-021.00e+003.4551124
GO:0050766positive regulation of phagocytosis8.74e-021.00e+003.4551124
GO:0000794condensed nuclear chromosome8.74e-021.00e+003.4551224
GO:0006206pyrimidine nucleobase metabolic process8.74e-021.00e+003.4551224
GO:0043388positive regulation of DNA binding8.74e-021.00e+003.4551124
GO:0005977glycogen metabolic process8.74e-021.00e+003.4551124
GO:2000379positive regulation of reactive oxygen species metabolic process8.74e-021.00e+003.4551124
GO:0016477cell migration8.86e-021.00e+002.00726131
GO:0042100B cell proliferation9.08e-021.00e+003.3961125
GO:0001816cytokine production9.08e-021.00e+003.3961125
GO:0001968fibronectin binding9.08e-021.00e+003.3961125
GO:0008536Ran GTPase binding9.08e-021.00e+003.3961225
GO:0051059NF-kappaB binding9.08e-021.00e+003.3961325
GO:0071479cellular response to ionizing radiation9.08e-021.00e+003.3961125
GO:0007569cell aging9.08e-021.00e+003.3961225
GO:0042113B cell activation9.08e-021.00e+003.3961225
GO:0017144drug metabolic process9.08e-021.00e+003.3961125
GO:0032735positive regulation of interleukin-12 production9.08e-021.00e+003.3961125
GO:0070979protein K11-linked ubiquitination9.43e-021.00e+003.3401326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia9.43e-021.00e+003.3401226
GO:0004519endonuclease activity9.43e-021.00e+003.3401126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway9.43e-021.00e+003.3401326
GO:0035987endodermal cell differentiation9.43e-021.00e+003.3401126
GO:0030148sphingolipid biosynthetic process9.43e-021.00e+003.3401126
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane9.43e-021.00e+003.3401126
GO:0006644phospholipid metabolic process9.55e-021.00e+001.94225137
GO:0004003ATP-dependent DNA helicase activity9.77e-021.00e+003.2851327
GO:0034080CENP-A containing nucleosome assembly9.77e-021.00e+003.2851227
GO:0030331estrogen receptor binding9.77e-021.00e+003.2851227
GO:0007339binding of sperm to zona pellucida9.77e-021.00e+003.2851127
GO:0007507heart development1.00e-011.00e+001.90125141
GO:0015991ATP hydrolysis coupled proton transport1.01e-011.00e+003.2331428
GO:0043022ribosome binding1.01e-011.00e+003.2331328
GO:0019894kinesin binding1.01e-011.00e+003.2331128
GO:0030177positive regulation of Wnt signaling pathway1.01e-011.00e+003.2331328
GO:0005739mitochondrion1.01e-011.00e+000.8177241046
GO:0008286insulin receptor signaling pathway1.04e-011.00e+001.87026144
GO:0019005SCF ubiquitin ligase complex1.05e-011.00e+003.1821129
GO:0003730mRNA 3'-UTR binding1.05e-011.00e+003.1821229
GO:0043198dendritic shaft1.05e-011.00e+003.1821129
GO:0010332response to gamma radiation1.05e-011.00e+003.1821229
GO:0003887DNA-directed DNA polymerase activity1.05e-011.00e+003.1821329
GO:0030669clathrin-coated endocytic vesicle membrane1.05e-011.00e+003.1821129
GO:0061024membrane organization1.06e-011.00e+001.85025146
GO:0006606protein import into nucleus1.08e-011.00e+003.1331130
GO:0001618virus receptor activity1.08e-011.00e+003.1331130
GO:0051262protein tetramerization1.08e-011.00e+003.1331330
GO:0042254ribosome biogenesis1.08e-011.00e+003.1331130
GO:0034504protein localization to nucleus1.08e-011.00e+003.1331230
GO:0021549cerebellum development1.08e-011.00e+003.1331130
GO:0035116embryonic hindlimb morphogenesis1.08e-011.00e+003.1331130
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator1.08e-011.00e+003.1331230
GO:0010628positive regulation of gene expression1.10e-011.00e+001.82124149
GO:0061077chaperone-mediated protein folding1.11e-011.00e+003.0861231
GO:0031623receptor internalization1.11e-011.00e+003.0861131
GO:0010827regulation of glucose transport1.11e-011.00e+003.0861131
GO:0046677response to antibiotic1.11e-011.00e+003.0861231
GO:0016604nuclear body1.11e-011.00e+003.0861231
GO:0007094mitotic spindle assembly checkpoint1.11e-011.00e+003.0861531
GO:0050661NADP binding1.15e-011.00e+003.0401132
GO:0002250adaptive immune response1.15e-011.00e+003.0401132
GO:0015992proton transport1.15e-011.00e+003.0401332
GO:0051219phosphoprotein binding1.15e-011.00e+003.0401332
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic1.15e-011.00e+003.0401132
GO:0032091negative regulation of protein binding1.18e-011.00e+002.9961133
GO:2001244positive regulation of intrinsic apoptotic signaling pathway1.18e-011.00e+002.9961133
GO:0045335phagocytic vesicle1.18e-011.00e+002.9961233
GO:0001837epithelial to mesenchymal transition1.18e-011.00e+002.9961133
GO:0033077T cell differentiation in thymus1.18e-011.00e+002.9961233
GO:0031072heat shock protein binding1.18e-011.00e+002.9961233
GO:0008094DNA-dependent ATPase activity1.21e-011.00e+002.9531134
GO:0008180COP9 signalosome1.21e-011.00e+002.9531134
GO:0046777protein autophosphorylation1.21e-011.00e+001.73623158
GO:0043407negative regulation of MAP kinase activity1.21e-011.00e+002.9531134
GO:0051701interaction with host1.21e-011.00e+002.9531434
GO:0005876spindle microtubule1.21e-011.00e+002.9531334
GO:0008543fibroblast growth factor receptor signaling pathway1.22e-011.00e+001.72724159
GO:2001237negative regulation of extrinsic apoptotic signaling pathway1.25e-011.00e+002.9111135
GO:0045599negative regulation of fat cell differentiation1.25e-011.00e+002.9111235
GO:0032588trans-Golgi network membrane1.28e-011.00e+002.8701136
GO:0034332adherens junction organization1.28e-011.00e+002.8701136
GO:0051402neuron apoptotic process1.28e-011.00e+002.8701236
GO:0032855positive regulation of Rac GTPase activity1.28e-011.00e+002.8701136
GO:0034446substrate adhesion-dependent cell spreading1.28e-011.00e+002.8701236
GO:0007411axon guidance1.28e-011.00e+001.27239327
GO:0032755positive regulation of interleukin-6 production1.28e-011.00e+002.8701236
GO:0006446regulation of translational initiation1.28e-011.00e+002.8701136
GO:0001895retina homeostasis1.28e-011.00e+002.8701136
GO:0000398mRNA splicing, via spliceosome1.30e-011.00e+001.674212165
GO:0051084'de novo' posttranslational protein folding1.31e-011.00e+002.8311437
GO:0005245voltage-gated calcium channel activity1.31e-011.00e+002.8311137
GO:0018107peptidyl-threonine phosphorylation1.31e-011.00e+002.8311137
GO:0003682chromatin binding1.34e-011.00e+001.242312334
GO:0001756somitogenesis1.35e-011.00e+002.7921138
GO:0070527platelet aggregation1.35e-011.00e+002.7921238
GO:0045740positive regulation of DNA replication1.35e-011.00e+002.7921238
GO:0090382phagosome maturation1.35e-011.00e+002.7921538
GO:0032729positive regulation of interferon-gamma production1.38e-011.00e+002.7551239
GO:0008033tRNA processing1.38e-011.00e+002.7551139
GO:0000737DNA catabolic process, endonucleolytic1.38e-011.00e+002.7551239
GO:0031490chromatin DNA binding1.38e-011.00e+002.7551239
GO:0007595lactation1.38e-011.00e+002.7551239
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.41e-011.00e+002.7181240
GO:0000781chromosome, telomeric region1.41e-011.00e+002.7181240
GO:0030145manganese ion binding1.45e-011.00e+002.6831141
GO:0017148negative regulation of translation1.45e-011.00e+002.6831141
GO:0030521androgen receptor signaling pathway1.45e-011.00e+002.6831241
GO:0045785positive regulation of cell adhesion1.45e-011.00e+002.6831541
GO:0043195terminal bouton1.45e-011.00e+002.6831141
GO:0006418tRNA aminoacylation for protein translation1.48e-011.00e+002.6481542
GO:0005902microvillus1.48e-011.00e+002.6481242
GO:0004715non-membrane spanning protein tyrosine kinase activity1.48e-011.00e+002.6481142
GO:0019904protein domain specific binding1.51e-011.00e+001.54026181
GO:0014070response to organic cyclic compound1.51e-011.00e+002.6141343
GO:0009897external side of plasma membrane1.53e-011.00e+001.52524183
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.54e-011.00e+002.5811344
GO:0007286spermatid development1.54e-011.00e+002.5811144
GO:0005080protein kinase C binding1.54e-011.00e+002.5811144
GO:0034613cellular protein localization1.54e-011.00e+002.5811144
GO:0006892post-Golgi vesicle-mediated transport1.54e-011.00e+002.5811244
GO:0006094gluconeogenesis1.58e-011.00e+002.5481345
GO:0043966histone H3 acetylation1.58e-011.00e+002.5481245
GO:0006631fatty acid metabolic process1.58e-011.00e+002.5481145
GO:0030136clathrin-coated vesicle1.61e-011.00e+002.5171146
GO:0044297cell body1.61e-011.00e+002.5171246
GO:0043525positive regulation of neuron apoptotic process1.61e-011.00e+002.5171246
GO:0045727positive regulation of translation1.61e-011.00e+002.5171446
GO:0021762substantia nigra development1.61e-011.00e+002.5171146
GO:0045665negative regulation of neuron differentiation1.61e-011.00e+002.5171246
GO:0030216keratinocyte differentiation1.64e-011.00e+002.4861147
GO:0007173epidermal growth factor receptor signaling pathway1.64e-011.00e+001.46324191
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.64e-011.00e+002.4861547
GO:0005507copper ion binding1.67e-011.00e+002.4551248
GO:0019827stem cell maintenance1.67e-011.00e+002.4551148
GO:0006950response to stress1.67e-011.00e+002.4551348
GO:0019003GDP binding1.67e-011.00e+002.4551248
GO:0031100organ regeneration1.74e-011.00e+002.3961450
GO:0001523retinoid metabolic process1.74e-011.00e+002.3961250
GO:0016049cell growth1.74e-011.00e+002.3961150
GO:0005905coated pit1.77e-011.00e+002.3681251
GO:0001669acrosomal vesicle1.77e-011.00e+002.3681151
GO:0000902cell morphogenesis1.77e-011.00e+002.3681251
GO:0030900forebrain development1.77e-011.00e+002.3681151
GO:0045444fat cell differentiation1.77e-011.00e+002.3681151
GO:0045732positive regulation of protein catabolic process1.77e-011.00e+002.3681451
GO:0034976response to endoplasmic reticulum stress1.80e-011.00e+002.3401152
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.85e-011.00e+000.838412589
GO:0090305nucleic acid phosphodiester bond hydrolysis1.86e-011.00e+002.2851254
GO:0007623circadian rhythm1.86e-011.00e+002.2851154
GO:0097193intrinsic apoptotic signaling pathway1.89e-011.00e+002.2591455
GO:0000226microtubule cytoskeleton organization1.89e-011.00e+002.2591355
GO:0001701in utero embryonic development1.90e-011.00e+001.32626210
GO:0004386helicase activity1.92e-011.00e+002.2331456
GO:0007613memory1.92e-011.00e+002.2331256
GO:0000932cytoplasmic mRNA processing body1.92e-011.00e+002.2331356
GO:0008104protein localization1.92e-011.00e+002.2331356
GO:0006968cellular defense response1.92e-011.00e+002.2331156
GO:0046982protein heterodimerization activity1.93e-011.00e+000.985311399
GO:0006879cellular iron ion homeostasis1.95e-011.00e+002.2071557
GO:0000724double-strand break repair via homologous recombination1.95e-011.00e+002.2071657
GO:0012505endomembrane system1.95e-011.00e+002.2071257
GO:0007202activation of phospholipase C activity1.98e-011.00e+002.1821158
GO:0002244hematopoietic progenitor cell differentiation1.98e-011.00e+002.1821158
GO:0045216cell-cell junction organization2.01e-011.00e+002.1581259
GO:0005840ribosome2.01e-011.00e+002.1581259
GO:0001570vasculogenesis2.01e-011.00e+002.1581159
GO:0031966mitochondrial membrane2.01e-011.00e+002.1581159
GO:0008013beta-catenin binding2.04e-011.00e+002.1331460
GO:0045087innate immune response2.06e-011.00e+000.773420616
GO:0033138positive regulation of peptidyl-serine phosphorylation2.08e-011.00e+002.1101361
GO:0006987activation of signaling protein activity involved in unfolded protein response2.11e-011.00e+002.0861262
GO:0005622intracellular2.12e-011.00e+001.22025226
GO:0042995cell projection2.14e-011.00e+002.0631663
GO:0009986cell surface2.16e-011.00e+000.90439422
GO:0032869cellular response to insulin stimulus2.17e-011.00e+002.0401364
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway2.17e-011.00e+002.0401164
GO:0019221cytokine-mediated signaling pathway2.17e-011.00e+001.19523230
GO:0008270zinc ion binding2.18e-011.00e+000.5666121067
GO:0008380RNA splicing2.20e-011.00e+001.182213232
GO:0030855epithelial cell differentiation2.20e-011.00e+002.0181465
GO:0006469negative regulation of protein kinase activity2.20e-011.00e+002.0181265
GO:0071260cellular response to mechanical stimulus2.23e-011.00e+001.9961466
GO:0006368transcription elongation from RNA polymerase II promoter2.25e-011.00e+001.9741667
GO:0030141secretory granule2.25e-011.00e+001.9741267
GO:0006665sphingolipid metabolic process2.28e-011.00e+001.9531268
GO:0009055electron carrier activity2.28e-011.00e+001.9531168
GO:0018105peptidyl-serine phosphorylation2.31e-011.00e+001.9321169
GO:0035264multicellular organism growth2.34e-011.00e+001.9111170
GO:0034329cell junction assembly2.37e-011.00e+001.8901171
GO:0008134transcription factor binding2.40e-011.00e+001.09828246
GO:0032587ruffle membrane2.40e-011.00e+001.8701472
GO:0003729mRNA binding2.43e-011.00e+001.8501473
GO:0032355response to estradiol2.43e-011.00e+001.8501573
GO:0055086nucleobase-containing small molecule metabolic process2.43e-011.00e+001.8501573
GO:0042826histone deacetylase binding2.46e-011.00e+001.8311174
GO:0007265Ras protein signal transduction2.49e-011.00e+001.8111375
GO:0060070canonical Wnt signaling pathway2.49e-011.00e+001.8111375
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation2.49e-011.00e+001.8111175
GO:0003677DNA binding2.51e-011.00e+000.4487261351
GO:0043025neuronal cell body2.51e-011.00e+001.05224254
GO:0006874cellular calcium ion homeostasis2.52e-011.00e+001.7921176
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process2.52e-011.00e+001.7921376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.55e-011.00e+001.7731577
GO:0008584male gonad development2.55e-011.00e+001.7731277
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process2.55e-011.00e+001.7731677
GO:0007229integrin-mediated signaling pathway2.57e-011.00e+001.7551278
GO:0007596blood coagulation2.58e-011.00e+000.767314464
GO:0006334nucleosome assembly2.60e-011.00e+001.7361479
GO:0006468protein phosphorylation2.61e-011.00e+000.758310467
GO:0002755MyD88-dependent toll-like receptor signaling pathway2.63e-011.00e+001.7181280
GO:0007565female pregnancy2.63e-011.00e+001.7181280
GO:0030968endoplasmic reticulum unfolded protein response2.66e-011.00e+001.7001281
GO:0001726ruffle2.69e-011.00e+001.6831482
GO:0043197dendritic spine2.71e-011.00e+001.6651283
GO:0000166nucleotide binding2.77e-011.00e+000.95326272
GO:0048011neurotrophin TRK receptor signaling pathway2.78e-011.00e+000.94726273
GO:0005975carbohydrate metabolic process2.79e-011.00e+000.94225274
GO:0043065positive regulation of apoptotic process2.79e-011.00e+000.94228274
GO:0006898receptor-mediated endocytosis2.80e-011.00e+001.6141286
GO:0006357regulation of transcription from RNA polymerase II promoter2.81e-011.00e+000.93726275
GO:0045893positive regulation of transcription, DNA-templated2.82e-011.00e+000.697317487
GO:0007283spermatogenesis2.82e-011.00e+000.93226276
GO:0007160cell-matrix adhesion2.85e-011.00e+001.5811388
GO:0050852T cell receptor signaling pathway2.85e-011.00e+001.5811288
GO:0090090negative regulation of canonical Wnt signaling pathway2.85e-011.00e+001.5811388
GO:0009887organ morphogenesis2.88e-011.00e+001.5651289
GO:0003690double-stranded DNA binding2.93e-011.00e+001.5321491
GO:0018279protein N-linked glycosylation via asparagine2.93e-011.00e+001.5321291
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.96e-011.00e+001.5171492
GO:0006928cellular component movement2.96e-011.00e+001.5171792
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity2.99e-011.00e+001.5011593
GO:0042493response to drug2.99e-011.00e+000.870211288
GO:0016311dephosphorylation3.01e-011.00e+001.4861394
GO:0016310phosphorylation3.04e-011.00e+001.4701295
GO:0030426growth cone3.09e-011.00e+001.4401397
GO:0030198extracellular matrix organization3.09e-011.00e+000.83623295
GO:0005743mitochondrial inner membrane3.16e-011.00e+000.81125300
GO:0004674protein serine/threonine kinase activity3.33e-011.00e+000.75526312
GO:0070588calcium ion transmembrane transport3.33e-011.00e+001.31211106
GO:0014069postsynaptic density3.33e-011.00e+001.31211106
GO:0005615extracellular space3.38e-011.00e+000.3825171010
GO:0035556intracellular signal transduction3.40e-011.00e+000.73226317
GO:0005815microtubule organizing center3.43e-011.00e+001.25914110
GO:0050900leukocyte migration3.46e-011.00e+001.24611111
GO:0006461protein complex assembly3.46e-011.00e+001.24616111
GO:0015630microtubule cytoskeleton3.48e-011.00e+001.23315112
GO:0030154cell differentiation3.51e-011.00e+000.69625325
GO:0043231intracellular membrane-bounded organelle3.60e-011.00e+000.66528332
GO:0006006glucose metabolic process3.65e-011.00e+001.14514119
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.71e-011.00e+000.377419811
GO:0032496response to lipopolysaccharide3.73e-011.00e+001.11014122
GO:0007568aging3.75e-011.00e+001.09813123
GO:0006511ubiquitin-dependent protein catabolic process3.84e-011.00e+001.05215127
GO:0030335positive regulation of cell migration3.91e-011.00e+001.01816130
GO:0007179transforming growth factor beta receptor signaling pathway3.91e-011.00e+001.01813130
GO:0018108peptidyl-tyrosine phosphorylation3.98e-011.00e+000.98513133
GO:0031982vesicle4.01e-011.00e+000.974110134
GO:0000086G2/M transition of mitotic cell cycle4.08e-011.00e+000.94217137
GO:0044255cellular lipid metabolic process4.14e-011.00e+000.91114140
GO:0016055Wnt signaling pathway4.17e-011.00e+000.90116141
GO:0005911cell-cell junction4.19e-011.00e+000.89013142
GO:0007155cell adhesion4.30e-011.00e+000.45528384
GO:0030246carbohydrate binding4.39e-011.00e+000.80211151
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription4.39e-011.00e+000.80212151
GO:0008284positive regulation of cell proliferation4.41e-011.00e+000.42628392
GO:0005788endoplasmic reticulum lumen4.51e-011.00e+000.74611157
GO:0005769early endosome4.54e-011.00e+000.73612158
GO:0006974cellular response to DNA damage stimulus4.54e-011.00e+000.73618158
GO:0005198structural molecule activity4.56e-011.00e+000.72714159
GO:0045121membrane raft4.60e-011.00e+000.70918161
GO:0006397mRNA processing4.76e-011.00e+000.63913169
GO:0044212transcription regulatory region DNA binding4.80e-011.00e+000.62216171
GO:0030424axon4.82e-011.00e+000.61413172
GO:0006886intracellular protein transport4.84e-011.00e+000.60614173
GO:0016607nuclear speck4.88e-011.00e+000.58914175
GO:0031965nuclear membrane4.90e-011.00e+000.58114176
GO:0004672protein kinase activity4.94e-011.00e+000.56512178
GO:0043687post-translational protein modification5.00e-011.00e+000.54014181
GO:0005578proteinaceous extracellular matrix5.04e-011.00e+000.52511183
GO:0006367transcription initiation from RNA polymerase II promoter5.06e-011.00e+000.51718184
GO:0032403protein complex binding5.07e-011.00e+000.50917185
GO:0001525angiogenesis5.35e-011.00e+000.39614200
GO:0006351transcription, DNA-templated5.66e-011.00e+00-0.0056251585
GO:0005765lysosomal membrane5.66e-011.00e+000.27215218
GO:0048471perinuclear region of cytoplasm5.95e-011.00e+000.010212523
GO:0006355regulation of transcription, DNA-templated6.12e-011.00e+00-0.0684171104
GO:0004842ubiquitin-protein transferase activity6.25e-011.00e+000.04014256
GO:0046872metal ion binding6.64e-011.00e+00-0.1555241465
GO:0007264small GTPase mediated signal transduction6.72e-011.00e+00-0.14013290
GO:0005783endoplasmic reticulum6.79e-011.00e+00-0.21229610
GO:0016567protein ubiquitination6.83e-011.00e+00-0.18415299
GO:0005856cytoskeleton6.97e-011.00e+00-0.24118311
GO:0007165signal transduction7.08e-011.00e+00-0.267317950
GO:0005794Golgi apparatus7.13e-011.00e+00-0.304214650
GO:0007275multicellular organismal development7.34e-011.00e+00-0.38615344
GO:0008285negative regulation of cell proliferation7.57e-011.00e+00-0.479111367
GO:0003700sequence-specific DNA binding transcription factor activity7.84e-011.00e+00-0.507211748
GO:0006508proteolysis7.94e-011.00e+00-0.63919410
GO:0006366transcription from RNA polymerase II promoter8.06e-011.00e+00-0.691112425
GO:0055114oxidation-reduction process8.44e-011.00e+00-0.870111481
GO:0055085transmembrane transport8.63e-011.00e+00-0.96518514
GO:0005886plasma membrane8.66e-011.00e+00-0.4288382834
GO:0005509calcium ion binding8.98e-011.00e+00-1.16218589
GO:0042803protein homodimerization activity9.09e-011.00e+00-1.229111617
GO:0005789endoplasmic reticulum membrane9.15e-011.00e+00-1.273110636
GO:0005887integral component of plasma membrane9.77e-011.00e+00-1.86817961
GO:0005576extracellular region9.84e-011.00e+00-1.995191049
GO:0016021integral component of membrane1.00e+001.00e+00-3.2381152483