Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.969 | 7.13e-17 | 1.14e-03 | 2.28e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMA3 | 5684 | 12 | 0.533 | 1.026 | 218 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
HNRNPC | 3183 | 20 | 1.812 | 1.026 | 119 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
ATP6V1B2 | 526 | 44 | 0.881 | 1.076 | 278 | - | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
[ TRIB3 ] | 57761 | 1 | 0.097 | 0.969 | 31 | - | - |
EEF2 | 1938 | 27 | 0.890 | 1.043 | 301 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
EFTUD2 | 9343 | 7 | 0.883 | 0.969 | 78 | Yes | - |
PSMB2 | 5690 | 18 | 0.877 | 1.026 | 117 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA2 | 5683 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | ATP6V1B2 | 526 | pp | -- | int.I2D: BioGrid_Yeast |
ATP6V1B2 | 526 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
HSPD1 | 3329 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd; int.HPRD: in vitro |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | TRIB3 | 57761 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
PSMA3 | 5684 | EFTUD2 | 9343 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | TRIB3 | 57761 | pp | -- | int.I2D: BioGrid |
PSMA3 | 5684 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
EEF2 | 1938 | HSPD1 | 3329 | pp | -- | int.I2D: YeastLow, YeastMedium |
EEF2 | 1938 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMA3 | 5684 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core |
ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
PSMA3 | 5684 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
PSMA3 | 5684 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 4.34e-14 | 6.26e-10 | 6.980 | 7 | 17 | 50 |
GO:0000502 | proteasome complex | 1.30e-13 | 1.88e-09 | 6.765 | 7 | 17 | 58 |
GO:0010467 | gene expression | 1.38e-13 | 1.99e-09 | 4.015 | 12 | 59 | 669 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.68e-13 | 3.86e-09 | 6.623 | 7 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.00e-13 | 4.33e-09 | 6.601 | 7 | 22 | 65 |
GO:0016071 | mRNA metabolic process | 4.48e-13 | 6.46e-09 | 5.185 | 9 | 31 | 223 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.15e-13 | 7.43e-09 | 6.494 | 7 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 6.32e-13 | 9.12e-09 | 6.454 | 7 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.72e-13 | 1.11e-08 | 6.414 | 7 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.50e-13 | 1.23e-08 | 6.395 | 7 | 20 | 75 |
GO:0016070 | RNA metabolic process | 1.13e-12 | 1.63e-08 | 5.038 | 9 | 32 | 247 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.24e-12 | 1.79e-08 | 6.320 | 7 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 3.72e-12 | 5.36e-08 | 6.100 | 7 | 21 | 92 |
GO:0005839 | proteasome core complex | 7.14e-12 | 1.03e-07 | 7.968 | 5 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 9.69e-12 | 1.40e-07 | 7.890 | 5 | 8 | 19 |
GO:0000209 | protein polyubiquitination | 1.95e-11 | 2.82e-07 | 5.765 | 7 | 20 | 116 |
GO:0016032 | viral process | 2.92e-11 | 4.21e-07 | 4.077 | 10 | 55 | 534 |
GO:0005829 | cytosol | 4.85e-11 | 6.99e-07 | 2.438 | 15 | 132 | 2496 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.15e-10 | 1.66e-06 | 5.404 | 7 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 1.21e-10 | 1.74e-06 | 5.395 | 7 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.04e-10 | 4.39e-06 | 5.206 | 7 | 20 | 171 |
GO:0070062 | extracellular vesicular exosome | 1.04e-09 | 1.50e-05 | 2.395 | 14 | 104 | 2400 |
GO:0043066 | negative regulation of apoptotic process | 5.47e-09 | 7.89e-05 | 4.088 | 8 | 31 | 424 |
GO:0005654 | nucleoplasm | 2.86e-08 | 4.12e-04 | 3.059 | 10 | 76 | 1082 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.25e-08 | 9.02e-04 | 8.401 | 3 | 4 | 8 |
GO:0000278 | mitotic cell cycle | 9.45e-08 | 1.36e-03 | 4.012 | 7 | 48 | 391 |
GO:0006915 | apoptotic process | 1.02e-06 | 1.47e-02 | 3.507 | 7 | 33 | 555 |
GO:0016020 | membrane | 1.86e-06 | 2.68e-02 | 2.423 | 10 | 90 | 1681 |
GO:0044281 | small molecule metabolic process | 1.68e-05 | 2.43e-01 | 2.574 | 8 | 58 | 1211 |
GO:0005838 | proteasome regulatory particle | 7.57e-05 | 1.00e+00 | 7.231 | 2 | 7 | 12 |
GO:0006414 | translational elongation | 1.37e-04 | 1.00e+00 | 4.862 | 3 | 13 | 93 |
GO:0022624 | proteasome accessory complex | 1.55e-04 | 1.00e+00 | 6.729 | 2 | 8 | 17 |
GO:0005515 | protein binding | 2.18e-04 | 1.00e+00 | 1.067 | 14 | 184 | 6024 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 4 | 23 |
GO:0005844 | polysome | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 4 | 23 |
GO:0031492 | nucleosomal DNA binding | 3.98e-04 | 1.00e+00 | 6.061 | 2 | 4 | 27 |
GO:0005634 | nucleus | 4.55e-04 | 1.00e+00 | 1.247 | 12 | 136 | 4559 |
GO:0044822 | poly(A) RNA binding | 6.42e-04 | 1.00e+00 | 2.357 | 6 | 49 | 1056 |
GO:0022627 | cytosolic small ribosomal subunit | 8.35e-04 | 1.00e+00 | 5.531 | 2 | 4 | 39 |
GO:0005730 | nucleolus | 1.10e-03 | 1.00e+00 | 1.943 | 7 | 69 | 1641 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0044267 | cellular protein metabolic process | 1.53e-03 | 1.00e+00 | 2.927 | 4 | 29 | 474 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1.54e-03 | 1.00e+00 | 5.088 | 2 | 5 | 53 |
GO:0006412 | translation | 1.92e-03 | 1.00e+00 | 3.556 | 3 | 20 | 230 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0071013 | catalytic step 2 spliceosome | 3.30e-03 | 1.00e+00 | 4.531 | 2 | 4 | 78 |
GO:0006458 | 'de novo' protein folding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0055106 | ubiquitin-protein transferase regulator activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0030135 | coated vesicle | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0019083 | viral transcription | 3.55e-03 | 1.00e+00 | 4.476 | 2 | 10 | 81 |
GO:0005681 | spliceosomal complex | 3.73e-03 | 1.00e+00 | 4.441 | 2 | 4 | 83 |
GO:0043234 | protein complex | 3.89e-03 | 1.00e+00 | 3.196 | 3 | 18 | 295 |
GO:0006415 | translational termination | 4.09e-03 | 1.00e+00 | 4.373 | 2 | 10 | 87 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0001649 | osteoblast differentiation | 4.56e-03 | 1.00e+00 | 4.293 | 2 | 6 | 92 |
GO:0019901 | protein kinase binding | 4.76e-03 | 1.00e+00 | 3.093 | 3 | 21 | 317 |
GO:0043248 | proteasome assembly | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0043405 | regulation of MAP kinase activity | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 5.79e-03 | 1.00e+00 | 4.116 | 2 | 10 | 104 |
GO:0003688 | DNA replication origin binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 6 |
GO:0030957 | Tat protein binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0030529 | ribonucleoprotein complex | 6.68e-03 | 1.00e+00 | 4.009 | 2 | 8 | 112 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 6.91e-03 | 1.00e+00 | 3.983 | 2 | 11 | 114 |
GO:0019058 | viral life cycle | 7.03e-03 | 1.00e+00 | 3.971 | 2 | 13 | 115 |
GO:0033180 | proton-transporting V-type ATPase, V1 domain | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0000028 | ribosomal small subunit assembly | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0000790 | nuclear chromatin | 8.78e-03 | 1.00e+00 | 3.805 | 2 | 9 | 129 |
GO:0070688 | MLL5-L complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0051604 | protein maturation | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0006413 | translational initiation | 9.04e-03 | 1.00e+00 | 3.783 | 2 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 9.85e-03 | 1.00e+00 | 3.718 | 2 | 10 | 137 |
GO:0045717 | negative regulation of fatty acid biosynthetic process | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0008494 | translation activator activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0008286 | insulin receptor signaling pathway | 1.06e-02 | 1.00e+00 | 3.666 | 2 | 7 | 142 |
GO:0043032 | positive regulation of macrophage activation | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 1 | 10 |
GO:0032727 | positive regulation of interferon-alpha production | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 11 |
GO:0045120 | pronucleus | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 2 | 11 |
GO:0051443 | positive regulation of ubiquitin-protein transferase activity | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 2 | 12 |
GO:0000398 | mRNA splicing, via spliceosome | 1.39e-02 | 1.00e+00 | 3.459 | 2 | 8 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.41e-02 | 1.00e+00 | 3.450 | 2 | 7 | 165 |
GO:0030234 | enzyme regulator activity | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0008266 | poly(U) RNA binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 4 | 14 |
GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 15 |
GO:0042026 | protein refolding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 15 |
GO:0046034 | ATP metabolic process | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 3 | 16 |
GO:0010243 | response to organonitrogen compound | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 17 |
GO:0003746 | translation elongation factor activity | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:0003924 | GTPase activity | 1.96e-02 | 1.00e+00 | 3.194 | 2 | 12 | 197 |
GO:0015078 | hydrogen ion transmembrane transporter activity | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 3 | 19 |
GO:0032733 | positive regulation of interleukin-10 production | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0006184 | GTP catabolic process | 2.29e-02 | 1.00e+00 | 3.075 | 2 | 12 | 214 |
GO:0042100 | B cell proliferation | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 21 |
GO:0004860 | protein kinase inhibitor activity | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 21 |
GO:0030863 | cortical cytoskeleton | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 4 | 22 |
GO:0043236 | laminin binding | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 2 | 23 |
GO:0008380 | RNA splicing | 2.58e-02 | 1.00e+00 | 2.983 | 2 | 11 | 228 |
GO:0042113 | B cell activation | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 1 | 25 |
GO:0003730 | mRNA 3'-UTR binding | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 2 | 26 |
GO:0015991 | ATP hydrolysis coupled proton transport | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 4 | 26 |
GO:0019843 | rRNA binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0019894 | kinesin binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 28 |
GO:0015992 | proton transport | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 3 | 29 |
GO:0033572 | transferrin transport | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 5 | 30 |
GO:0010827 | regulation of glucose transport | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 30 |
GO:0051701 | interaction with host | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 4 | 32 |
GO:0016301 | kinase activity | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 3 | 33 |
GO:0001895 | retina homeostasis | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 1 | 34 |
GO:0045599 | negative regulation of fat cell differentiation | 3.81e-02 | 1.00e+00 | 4.687 | 1 | 2 | 35 |
GO:0034332 | adherens junction organization | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 36 |
GO:0090382 | phagosome maturation | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 5 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.03e-02 | 1.00e+00 | 4.607 | 1 | 4 | 37 |
GO:0005902 | microvillus | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0032092 | positive regulation of protein binding | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 3 | 38 |
GO:0070527 | platelet aggregation | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 2 | 39 |
GO:0005525 | GTP binding | 4.53e-02 | 1.00e+00 | 2.540 | 2 | 12 | 310 |
GO:0042110 | T cell activation | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 3 | 42 |
GO:0014070 | response to organic cyclic compound | 4.67e-02 | 1.00e+00 | 4.390 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 2 | 44 |
GO:0015030 | Cajal body | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0045727 | positive regulation of translation | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0005524 | ATP binding | 4.95e-02 | 1.00e+00 | 1.474 | 4 | 60 | 1298 |
GO:0006986 | response to unfolded protein | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 2 | 50 |
GO:0003723 | RNA binding | 5.41e-02 | 1.00e+00 | 2.398 | 2 | 20 | 342 |
GO:0005905 | coated pit | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 3 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 5.51e-02 | 1.00e+00 | 4.144 | 1 | 1 | 51 |
GO:0006879 | cellular iron ion homeostasis | 5.51e-02 | 1.00e+00 | 4.144 | 1 | 4 | 51 |
GO:0003725 | double-stranded RNA binding | 5.62e-02 | 1.00e+00 | 4.116 | 1 | 5 | 52 |
GO:0002244 | hematopoietic progenitor cell differentiation | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 54 |
GO:0045216 | cell-cell junction organization | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 54 |
GO:0002039 | p53 binding | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 7 | 55 |
GO:0012505 | endomembrane system | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 2 | 56 |
GO:0005925 | focal adhesion | 6.10e-02 | 1.00e+00 | 2.300 | 2 | 19 | 366 |
GO:0005840 | ribosome | 6.25e-02 | 1.00e+00 | 3.958 | 1 | 1 | 58 |
GO:0051087 | chaperone binding | 6.35e-02 | 1.00e+00 | 3.933 | 1 | 6 | 59 |
GO:0030141 | secretory granule | 6.66e-02 | 1.00e+00 | 3.862 | 1 | 2 | 62 |
GO:0032869 | cellular response to insulin stimulus | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 3 | 63 |
GO:0006469 | negative regulation of protein kinase activity | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 4 | 65 |
GO:0034329 | cell junction assembly | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 5 | 68 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.90e-02 | 1.00e+00 | 3.607 | 1 | 6 | 74 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 8.21e-02 | 1.00e+00 | 3.549 | 1 | 7 | 77 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 8.52e-02 | 1.00e+00 | 3.494 | 1 | 3 | 80 |
GO:0001726 | ruffle | 8.52e-02 | 1.00e+00 | 3.494 | 1 | 4 | 80 |
GO:0050821 | protein stabilization | 9.33e-02 | 1.00e+00 | 3.357 | 1 | 2 | 88 |
GO:0042470 | melanosome | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 8 | 91 |
GO:0051082 | unfolded protein binding | 9.84e-02 | 1.00e+00 | 3.277 | 1 | 5 | 93 |
GO:0014069 | postsynaptic density | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 1.15e-01 | 1.00e+00 | 3.035 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 1.16e-01 | 1.00e+00 | 3.022 | 1 | 3 | 111 |
GO:0048015 | phosphatidylinositol-mediated signaling | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 7 | 114 |
GO:0006325 | chromatin organization | 1.23e-01 | 1.00e+00 | 2.933 | 1 | 5 | 118 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0044255 | cellular lipid metabolic process | 1.38e-01 | 1.00e+00 | 2.761 | 1 | 6 | 133 |
GO:0045087 | innate immune response | 1.40e-01 | 1.00e+00 | 1.597 | 2 | 24 | 596 |
GO:0016887 | ATPase activity | 1.45e-01 | 1.00e+00 | 2.687 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.47e-01 | 1.00e+00 | 2.656 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.49e-01 | 1.00e+00 | 2.636 | 1 | 7 | 145 |
GO:0010628 | positive regulation of gene expression | 1.50e-01 | 1.00e+00 | 2.626 | 1 | 5 | 146 |
GO:0005769 | early endosome | 1.56e-01 | 1.00e+00 | 2.568 | 1 | 2 | 152 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.60e-01 | 1.00e+00 | 2.531 | 1 | 9 | 156 |
GO:0006397 | mRNA processing | 1.64e-01 | 1.00e+00 | 2.494 | 1 | 2 | 160 |
GO:0030424 | axon | 1.69e-01 | 1.00e+00 | 2.441 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.71e-01 | 1.00e+00 | 2.424 | 1 | 12 | 168 |
GO:0016607 | nuclear speck | 1.75e-01 | 1.00e+00 | 2.390 | 1 | 3 | 172 |
GO:0031625 | ubiquitin protein ligase binding | 1.80e-01 | 1.00e+00 | 2.340 | 1 | 14 | 178 |
GO:0003714 | transcription corepressor activity | 1.80e-01 | 1.00e+00 | 2.340 | 1 | 8 | 178 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 12 | 189 |
GO:0005765 | lysosomal membrane | 2.03e-01 | 1.00e+00 | 2.151 | 1 | 5 | 203 |
GO:0005737 | cytoplasm | 2.20e-01 | 1.00e+00 | 0.522 | 6 | 110 | 3767 |
GO:0005759 | mitochondrial matrix | 2.25e-01 | 1.00e+00 | 1.983 | 1 | 14 | 228 |
GO:0000166 | nucleotide binding | 2.52e-01 | 1.00e+00 | 1.799 | 1 | 5 | 259 |
GO:0043065 | positive regulation of apoptotic process | 2.59e-01 | 1.00e+00 | 1.750 | 1 | 10 | 268 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.60e-01 | 1.00e+00 | 1.745 | 1 | 15 | 269 |
GO:0005743 | mitochondrial inner membrane | 2.67e-01 | 1.00e+00 | 1.702 | 1 | 8 | 277 |
GO:0005856 | cytoskeleton | 2.78e-01 | 1.00e+00 | 1.631 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.79e-01 | 1.00e+00 | 1.626 | 1 | 15 | 292 |
GO:0005615 | extracellular space | 2.88e-01 | 1.00e+00 | 0.914 | 2 | 17 | 957 |
GO:0043231 | intracellular membrane-bounded organelle | 3.00e-01 | 1.00e+00 | 1.503 | 1 | 9 | 318 |
GO:0007411 | axon guidance | 3.01e-01 | 1.00e+00 | 1.499 | 1 | 13 | 319 |
GO:0005813 | centrosome | 3.06e-01 | 1.00e+00 | 1.467 | 1 | 14 | 326 |
GO:0005886 | plasma membrane | 3.18e-01 | 1.00e+00 | 0.482 | 4 | 45 | 2582 |
GO:0007155 | cell adhesion | 3.40e-01 | 1.00e+00 | 1.289 | 1 | 6 | 369 |
GO:0009986 | cell surface | 3.64e-01 | 1.00e+00 | 1.165 | 1 | 11 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.72e-01 | 1.00e+00 | 1.126 | 1 | 15 | 413 |
GO:0055085 | transmembrane transport | 3.88e-01 | 1.00e+00 | 1.051 | 1 | 10 | 435 |
GO:0007596 | blood coagulation | 4.01e-01 | 1.00e+00 | 0.986 | 1 | 18 | 455 |
GO:0006468 | protein phosphorylation | 4.05e-01 | 1.00e+00 | 0.971 | 1 | 18 | 460 |
GO:0042802 | identical protein binding | 4.21e-01 | 1.00e+00 | 0.897 | 1 | 20 | 484 |
GO:0005739 | mitochondrion | 6.83e-01 | 1.00e+00 | -0.147 | 1 | 28 | 998 |
GO:0006351 | transcription, DNA-templated | 8.16e-01 | 1.00e+00 | -0.682 | 1 | 31 | 1446 |
GO:0016021 | integral component of membrane | 9.06e-01 | 1.00e+00 | -1.137 | 1 | 27 | 1982 |