int-snw-3305

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.942 8.57e-16 2.11e-03 3.57e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-3305 subnetwork

Genes (23)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 120.5331.026218Yes-
PSMA2 5683 601.0931.10689Yes-
HNRNPC 3183 201.8121.026119Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
OGDH 4967 130.8471.076113Yes-
ATP6V1B2 526 440.8811.076278--
RPSA 3921 1561.3271.151152Yes-
[ HSPA1L ] 3305 1-0.4140.942125-Yes
ACO2 50 501.0001.076191Yes-
EEF2 1938 270.8901.043301Yes-
RUVBL1 8607 170.7201.013343Yes-
PSMD13 5719 160.8481.029104Yes-
PSMD3 5709 570.9861.106146Yes-
RPS11 6205 360.9931.113175Yes-
CLTC 1213 350.8841.138247Yes-
EFTUD2 9343 70.8830.96978Yes-
PSMB2 5690 180.8771.026117Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
RUVBL2 10856 50.6931.003345Yes-
HSPD1 3329 350.9131.035286Yes-
PSMD6 9861 110.8481.009131Yes-

Interactions (91)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
OGDH 4967 PSMD6 9861 pp -- int.I2D: YeastLow
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
ACO2 50 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
HSPA1L 3305 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPA1L 3305 PSMA3 5684 pp -- int.I2D: BioGrid
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD13 5719 pp -- int.I2D: YeastLow
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
OGDH 4967 PSMD13 5719 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
HSPD1 3329 OGDH 4967 pp -- int.I2D: YeastLow
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
HSPA1L 3305 RUVBL2 10856 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
RPS11 6205 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACO2 50 OGDH 4967 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ATP6V1B2 526 OGDH 4967 pp -- int.I2D: IntAct_Yeast
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMD13 5719 RUVBL2 10856 pp -- int.I2D: YeastHigh
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core

Related GO terms (278)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006521regulation of cellular amino acid metabolic process2.66e-173.84e-136.81991750
GO:0000502proteasome complex1.12e-161.62e-126.60491758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.89e-164.17e-126.46291964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.35e-164.83e-126.44092265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.79e-169.79e-126.33392270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent8.87e-161.28e-116.29392072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.15e-151.66e-116.25392274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.30e-151.88e-116.23492075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.13e-153.07e-116.15992379
GO:0002474antigen processing and presentation of peptide antigen via MHC class I8.89e-151.28e-105.93992192
GO:0016071mRNA metabolic process1.08e-141.56e-104.9511131223
GO:0016070RNA metabolic process3.36e-144.84e-104.8041132247
GO:0034641cellular nitrogen compound metabolic process4.22e-146.08e-105.1971020171
GO:0000209protein polyubiquitination7.64e-141.10e-095.604920116
GO:0010467gene expression1.04e-131.49e-093.7141459669
GO:0000082G1/S transition of mitotic cell cycle7.59e-131.09e-085.243932149
GO:0042981regulation of apoptotic process8.07e-131.16e-085.234924150
GO:0016032viral process5.48e-127.90e-083.8171255534
GO:0070062extracellular vesicular exosome6.71e-129.68e-082.312191042400
GO:0005839proteasome core complex5.47e-117.89e-077.4455818
GO:0005654nucleoplasm7.09e-111.02e-063.02014761082
GO:0004298threonine-type endopeptidase activity7.42e-111.07e-067.3675819
GO:0005829cytosol2.55e-103.68e-062.177181322496
GO:0043066negative regulation of apoptotic process3.53e-105.08e-063.8871031424
GO:0000278mitotic cell cycle4.21e-096.08e-053.851948391
GO:0022624proteasome accessory complex1.15e-081.66e-047.2054817
GO:0016020membrane2.38e-083.44e-042.38514901681
GO:0006915apoptotic process8.74e-081.26e-033.346933555
GO:0019773proteasome core complex, alpha-subunit complex1.97e-072.85e-037.877348
GO:0044281small molecule metabolic process7.33e-071.06e-022.51011581211
GO:0005838proteasome regulatory particle7.72e-071.11e-027.2933712
GO:0035267NuA4 histone acetyltransferase complex1.27e-061.84e-027.0703414
GO:0030529ribonucleoprotein complex2.72e-053.93e-014.48548112
GO:0016887ATPase activity6.52e-059.41e-014.16347140
GO:0000812Swr1 complex6.77e-059.77e-017.293238
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding7.88e-051.00e+005.1503553
GO:0043968histone H2A acetylation1.59e-041.00e+006.7082312
GO:0031011Ino80 complex2.19e-041.00e+006.4852314
GO:0042026protein refolding2.52e-041.00e+006.3862215
GO:0003678DNA helicase activity3.26e-041.00e+006.2052317
GO:0001649osteoblast differentiation4.06e-041.00e+004.3543692
GO:0006414translational elongation4.19e-041.00e+004.33831393
GO:0051082unfolded protein binding4.19e-041.00e+004.3383593
GO:0005759mitochondrial matrix4.25e-041.00e+003.460414228
GO:0043044ATP-dependent chromatin remodeling6.03e-041.00e+005.7692423
GO:0005844polysome6.03e-041.00e+005.7692423
GO:0071339MLL1 complex8.33e-041.00e+005.5382327
GO:0043967histone H4 acetylation8.33e-041.00e+005.5382327
GO:0031492nucleosomal DNA binding8.33e-041.00e+005.5382427
GO:0006325chromatin organization8.39e-041.00e+003.99535118
GO:0006099tricarboxylic acid cycle8.97e-041.00e+005.4852428
GO:0005634nucleus9.37e-041.00e+001.045151364559
GO:0044822poly(A) RNA binding9.56e-041.00e+002.0557491056
GO:0033572transferrin transport1.03e-031.00e+005.3862530
GO:0043234protein complex1.12e-031.00e+003.088418295
GO:0002842positive regulation of T cell mediated immune response to tumor cell1.59e-031.00e+009.293111
GO:0048291isotype switching to IgG isotypes1.59e-031.00e+009.293111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity1.59e-031.00e+009.293111
GO:0002368B cell cytokine production1.59e-031.00e+009.293111
GO:0022627cytosolic small ribosomal subunit1.74e-031.00e+005.0072439
GO:0005515protein binding1.81e-031.00e+000.823171846024
GO:0032508DNA duplex unwinding1.92e-031.00e+004.9352341
GO:0005730nucleolus2.81e-031.00e+001.6128691641
GO:0006091generation of precursor metabolites and energy2.84e-031.00e+004.6492350
GO:0006986response to unfolded protein2.84e-031.00e+004.6492250
GO:0040008regulation of growth2.84e-031.00e+004.6492550
GO:0003725double-stranded RNA binding3.07e-031.00e+004.5922552
GO:0045252oxoglutarate dehydrogenase complex3.19e-031.00e+008.293122
GO:00515383 iron, 4 sulfur cluster binding3.19e-031.00e+008.293112
GO:0003994aconitate hydratase activity3.19e-031.00e+008.293112
GO:0006407rRNA export from nucleus3.19e-031.00e+008.293112
GO:0061034olfactory bulb mitral cell layer development3.19e-031.00e+008.293112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)3.19e-031.00e+008.293112
GO:0005055laminin receptor activity3.19e-031.00e+008.293112
GO:0007127meiosis I3.19e-031.00e+008.293112
GO:0051087chaperone binding3.94e-031.00e+004.4102659
GO:0006310DNA recombination4.76e-031.00e+004.2702265
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity4.78e-031.00e+007.708113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb4.78e-031.00e+007.708113
GO:0071899negative regulation of estrogen receptor binding4.78e-031.00e+007.708113
GO:1900126negative regulation of hyaluronan biosynthetic process4.78e-031.00e+007.708123
GO:0006458'de novo' protein folding4.78e-031.00e+007.708113
GO:0071733transcriptional activation by promoter-enhancer looping4.78e-031.00e+007.708113
GO:0030135coated vesicle4.78e-031.00e+007.708113
GO:0071439clathrin complex4.78e-031.00e+007.708123
GO:0006412translation5.60e-031.00e+003.032320230
GO:0044267cellular protein metabolic process6.21e-031.00e+002.404429474
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.36e-031.00e+007.293114
GO:003068690S preribosome6.36e-031.00e+007.293114
GO:0032051clathrin light chain binding6.36e-031.00e+007.293114
GO:0043141ATP-dependent 5'-3' DNA helicase activity6.36e-031.00e+007.293114
GO:0006104succinyl-CoA metabolic process6.36e-031.00e+007.293114
GO:0006734NADH metabolic process6.36e-031.00e+007.293114
GO:1903077negative regulation of protein localization to plasma membrane6.36e-031.00e+007.293114
GO:0071013catalytic step 2 spliceosome6.79e-031.00e+004.0072478
GO:0019083viral transcription7.30e-031.00e+003.95321081
GO:0005681spliceosomal complex7.65e-031.00e+003.9172483
GO:0071169establishment of protein localization to chromatin7.95e-031.00e+006.971115
GO:0043248proteasome assembly7.95e-031.00e+006.971115
GO:0046696lipopolysaccharide receptor complex7.95e-031.00e+006.971115
GO:0006102isocitrate metabolic process7.95e-031.00e+006.971115
GO:0030976thiamine pyrophosphate binding7.95e-031.00e+006.971115
GO:0006415translational termination8.38e-031.00e+003.85021087
GO:0016363nuclear matrix9.14e-031.00e+003.78521291
GO:0042470melanosome9.14e-031.00e+003.7852991
GO:0003688DNA replication origin binding9.53e-031.00e+006.708126
GO:0030130clathrin coat of trans-Golgi network vesicle9.53e-031.00e+006.708136
GO:0006101citrate metabolic process9.53e-031.00e+006.708116
GO:0021860pyramidal neuron development9.53e-031.00e+006.708116
GO:0030118clathrin coat9.53e-031.00e+006.708126
GO:0021695cerebellar cortex development9.53e-031.00e+006.708126
GO:0030957Tat protein binding9.53e-031.00e+006.708136
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex9.53e-031.00e+006.708116
GO:0006200ATP catabolic process1.08e-021.00e+002.688315292
GO:0000028ribosomal small subunit assembly1.11e-021.00e+006.485117
GO:0033180proton-transporting V-type ATPase, V1 domain1.11e-021.00e+006.485127
GO:0030132clathrin coat of coated pit1.11e-021.00e+006.485127
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.18e-021.00e+003.592210104
GO:0070688MLL5-L complex1.27e-021.00e+006.293118
GO:0006554lysine catabolic process1.27e-021.00e+006.293128
GO:0051604protein maturation1.27e-021.00e+006.293118
GO:0019901protein kinase binding1.34e-021.00e+002.569321317
GO:0072562blood microparticle1.34e-021.00e+003.49823111
GO:0005524ATP binding1.39e-021.00e+001.5356601298
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.41e-021.00e+003.460211114
GO:0019058viral life cycle1.43e-021.00e+003.447213115
GO:0008494translation activator activity1.43e-021.00e+006.123119
GO:0044237cellular metabolic process1.48e-021.00e+003.42225117
GO:0002199zona pellucida receptor complex1.58e-021.00e+005.9711110
GO:0043032positive regulation of macrophage activation1.58e-021.00e+005.9711110
GO:0021756striatum development1.58e-021.00e+005.9711110
GO:0032727positive regulation of interferon-alpha production1.74e-021.00e+005.8331111
GO:0045120pronucleus1.74e-021.00e+005.8331211
GO:0021794thalamus development1.74e-021.00e+005.8331111
GO:0000790nuclear chromatin1.78e-021.00e+003.28129129
GO:0006413translational initiation1.83e-021.00e+003.259217131
GO:00709353'-UTR-mediated mRNA stabilization1.90e-021.00e+005.7081212
GO:0005925focal adhesion1.97e-021.00e+002.362319366
GO:0003735structural constituent of ribosome1.99e-021.00e+003.194210137
GO:0030234enzyme regulator activity2.05e-021.00e+005.5921313
GO:0001530lipopolysaccharide binding2.05e-021.00e+005.5921313
GO:0008266poly(U) RNA binding2.05e-021.00e+005.5921113
GO:0051131chaperone-mediated protein complex assembly2.05e-021.00e+005.5921113
GO:0006457protein folding2.16e-021.00e+003.13327143
GO:0061024membrane organization2.21e-021.00e+003.11327145
GO:0035066positive regulation of histone acetylation2.37e-021.00e+005.3861115
GO:0046034ATP metabolic process2.37e-021.00e+005.3861115
GO:0046961proton-transporting ATPase activity, rotational mechanism2.37e-021.00e+005.3861315
GO:0042176regulation of protein catabolic process2.52e-021.00e+005.2931316
GO:0050998nitric-oxide synthase binding2.52e-021.00e+005.2931116
GO:00061032-oxoglutarate metabolic process2.52e-021.00e+005.2931116
GO:0010243response to organonitrogen compound2.68e-021.00e+005.2051317
GO:0003746translation elongation factor activity2.68e-021.00e+005.2051317
GO:0050870positive regulation of T cell activation2.68e-021.00e+005.2051117
GO:0000398mRNA splicing, via spliceosome2.78e-021.00e+002.93528164
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.81e-021.00e+002.92627165
GO:0071392cellular response to estradiol stimulus2.83e-021.00e+005.1231118
GO:0015078hydrogen ion transmembrane transporter activity2.99e-021.00e+005.0451319
GO:0048863stem cell differentiation2.99e-021.00e+005.0451119
GO:0032733positive regulation of interleukin-10 production2.99e-021.00e+005.0451119
GO:0005719nuclear euchromatin2.99e-021.00e+005.0451219
GO:0042100B cell proliferation3.30e-021.00e+004.9001121
GO:0030863cortical cytoskeleton3.45e-021.00e+004.8331122
GO:0036464cytoplasmic ribonucleoprotein granule3.45e-021.00e+004.8331422
GO:0043236laminin binding3.61e-021.00e+004.7691123
GO:0003924GTPase activity3.89e-021.00e+002.670212197
GO:0034080CENP-A containing nucleosome assembly3.91e-021.00e+004.6491125
GO:0007339binding of sperm to zona pellucida3.91e-021.00e+004.6491125
GO:0042113B cell activation3.91e-021.00e+004.6491225
GO:0032735positive regulation of interleukin-12 production3.91e-021.00e+004.6491125
GO:0015991ATP hydrolysis coupled proton transport4.07e-021.00e+004.5921426
GO:0003730mRNA 3'-UTR binding4.07e-021.00e+004.5921226
GO:0004003ATP-dependent DNA helicase activity4.22e-021.00e+004.5381227
GO:0019843rRNA binding4.22e-021.00e+004.5381327
GO:0043022ribosome binding4.22e-021.00e+004.5381327
GO:0030669clathrin-coated endocytic vesicle membrane4.37e-021.00e+004.4851428
GO:0019894kinesin binding4.37e-021.00e+004.4851128
GO:0006184GTP catabolic process4.52e-021.00e+002.551212214
GO:0015992proton transport4.53e-021.00e+004.4351329
GO:0034644cellular response to UV4.68e-021.00e+004.3861530
GO:0031623receptor internalization4.83e-021.00e+004.3381231
GO:0051701interaction with host4.98e-021.00e+004.2931432
GO:0007067mitotic nuclear division5.02e-021.00e+002.466214227
GO:0008380RNA splicing5.06e-021.00e+002.460211228
GO:0031072heat shock protein binding5.14e-021.00e+004.2481133
GO:0032588trans-Golgi network membrane5.29e-021.00e+004.2051234
GO:0008180COP9 signalosome5.29e-021.00e+004.2051134
GO:0001895retina homeostasis5.29e-021.00e+004.2051134
GO:00515394 iron, 4 sulfur cluster binding5.44e-021.00e+004.1631335
GO:0034332adherens junction organization5.59e-021.00e+004.1231136
GO:0090382phagosome maturation5.59e-021.00e+004.1231536
GO:0032755positive regulation of interleukin-6 production5.59e-021.00e+004.1231236
GO:0051084'de novo' posttranslational protein folding5.74e-021.00e+004.0831437
GO:0021766hippocampus development5.89e-021.00e+004.0451438
GO:0005902microvillus5.89e-021.00e+004.0451238
GO:0031490chromatin DNA binding5.89e-021.00e+004.0451338
GO:0006096glycolytic process5.89e-021.00e+004.0451438
GO:0070527platelet aggregation5.89e-021.00e+004.0451238
GO:0032729positive regulation of interferon-gamma production6.04e-021.00e+004.0071239
GO:0006281DNA repair6.43e-021.00e+002.265218261
GO:0042110T cell activation6.49e-021.00e+003.9001342
GO:0030136clathrin-coated vesicle6.49e-021.00e+003.9001442
GO:0006892post-Golgi vesicle-mediated transport6.64e-021.00e+003.8661343
GO:0014070response to organic cyclic compound6.64e-021.00e+003.8661443
GO:0021762substantia nigra development6.79e-021.00e+003.8331244
GO:0015030Cajal body6.79e-021.00e+003.8331344
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding6.79e-021.00e+003.8331244
GO:0045727positive regulation of translation6.79e-021.00e+003.8331344
GO:0044297cell body7.09e-021.00e+003.7691246
GO:0003684damaged DNA binding7.53e-021.00e+003.6781749
GO:0005905coated pit7.68e-021.00e+003.6491350
GO:0006879cellular iron ion homeostasis7.83e-021.00e+003.6201451
GO:0045216cell-cell junction organization8.27e-021.00e+003.5381254
GO:0000932cytoplasmic mRNA processing body8.27e-021.00e+003.5381354
GO:0002244hematopoietic progenitor cell differentiation8.27e-021.00e+003.5381154
GO:0002039p53 binding8.42e-021.00e+003.5111755
GO:0031966mitochondrial membrane8.42e-021.00e+003.5111155
GO:0012505endomembrane system8.57e-021.00e+003.4851256
GO:0005525GTP binding8.67e-021.00e+002.016212310
GO:0005840ribosome8.86e-021.00e+003.4351158
GO:0043231intracellular membrane-bounded organelle9.05e-021.00e+001.98029318
GO:0030141secretory granule9.44e-021.00e+003.3381262
GO:0006338chromatin remodeling1.00e-011.00e+003.2481566
GO:0003723RNA binding1.02e-011.00e+001.875220342
GO:0003697single-stranded DNA binding1.03e-011.00e+003.2051568
GO:0034329cell junction assembly1.03e-011.00e+003.2051168
GO:0006334nucleosome assembly1.09e-011.00e+003.1231272
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.12e-011.00e+003.0831674
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.16e-011.00e+003.0261777
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.20e-011.00e+002.9711380
GO:0001726ruffle1.20e-011.00e+002.9711480
GO:0006898receptor-mediated endocytosis1.26e-011.00e+002.9001384
GO:0050821protein stabilization1.31e-011.00e+002.8331288
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.34e-011.00e+002.8011790
GO:0006928cellular component movement1.36e-011.00e+002.7851791
GO:0005200structural constituent of cytoskeleton1.36e-011.00e+002.7851891
GO:0014069postsynaptic density1.55e-011.00e+002.57813105
GO:0005506iron ion binding1.55e-011.00e+002.57814105
GO:0005815microtubule organizing center1.60e-011.00e+002.52415109
GO:0015630microtubule cytoskeleton1.62e-011.00e+002.51114110
GO:0005819spindle1.64e-011.00e+002.48517112
GO:0042802identical protein binding1.80e-011.00e+001.374220484
GO:0009615response to virus1.83e-011.00e+002.31515126
GO:0006511ubiquitin-dependent protein catabolic process1.83e-011.00e+002.31515126
GO:0031982vesicle1.89e-011.00e+002.25919131
GO:0008286insulin receptor signaling pathway2.04e-011.00e+002.14317142
GO:0010628positive regulation of gene expression2.09e-011.00e+002.10315146
GO:0005739mitochondrion2.10e-011.00e+000.915328998
GO:0005198structural molecule activity2.14e-011.00e+002.06415150
GO:0005769early endosome2.16e-011.00e+002.04512152
GO:0006397mRNA processing2.26e-011.00e+001.97112160
GO:0005737cytoplasm2.33e-011.00e+000.41381103767
GO:0030424axon2.34e-011.00e+001.91714166
GO:0006886intracellular protein transport2.40e-011.00e+001.87515171
GO:0016607nuclear speck2.41e-011.00e+001.86613172
GO:0005765lysosomal membrane2.78e-011.00e+001.62715203
GO:0005622intracellular2.83e-011.00e+001.59916207
GO:0000166nucleotide binding3.41e-011.00e+001.27615259
GO:0007283spermatogenesis3.44e-011.00e+001.25918262
GO:0006357regulation of transcription from RNA polymerase II promoter3.46e-011.00e+001.24818264
GO:0043065positive regulation of apoptotic process3.51e-011.00e+001.226110268
GO:0005743mitochondrial inner membrane3.60e-011.00e+001.17918277
GO:0005856cytoskeleton3.74e-011.00e+001.108112291
GO:0007411axon guidance4.02e-011.00e+000.975113319
GO:0005813centrosome4.09e-011.00e+000.944114326
GO:0007155cell adhesion4.49e-011.00e+000.76516369
GO:0005615extracellular space4.57e-011.00e+000.390217957
GO:0006508proteolysis4.57e-011.00e+000.73019378
GO:0009986cell surface4.78e-011.00e+000.641111402
GO:0055085transmembrane transport5.06e-011.00e+000.528110435
GO:0007596blood coagulation5.22e-011.00e+000.463118455
GO:0005886plasma membrane6.10e-011.00e+00-0.0424452582
GO:0045087innate immune response6.21e-011.00e+000.073124596
GO:0005794Golgi apparatus6.30e-011.00e+000.040115610
GO:0006351transcription, DNA-templated6.87e-011.00e+00-0.2052311446
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.26e-011.00e+00-0.331119789
GO:0046872metal ion binding8.88e-011.00e+00-1.0601251307
GO:0016021integral component of membrane9.67e-011.00e+00-1.6601271982