int-snw-2957

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.941 9.03e-16 2.14e-03 3.61e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-2957 subnetwork

Genes (25)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RBX1 9978 971.1851.151139Yes-
PHB2 11331 90.8291.076140Yes-
HNRNPC 3183 201.8121.026119Yes-
RPL6 6128 110.8441.113164Yes-
PSMB7 5695 480.9821.05257Yes-
SMARCA4 6597 10.4160.941253--
PSMA1 5682 610.9961.052123Yes-
ATP6V1B2 526 440.8811.076278--
RPSA 3921 1561.3271.151152Yes-
RPS3A 6189 110.8351.069166Yes-
RPA2 6118 981.2501.15169Yes-
CAD 790 170.8071.007333--
CDC16 8881 250.9501.02080Yes-
[ GTF2A1 ] 2957 10.2510.94152--
EEF2 1938 270.8901.043301Yes-
PSMD13 5719 160.8481.029104Yes-
PSMD3 5709 570.9861.106146Yes-
CLTC 1213 350.8841.138247Yes-
PSMB2 5690 180.8771.026117Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
PSMD6 9861 110.8481.009131Yes-
FBL 2091 70.8391.15165Yes-
HSPD1 3329 350.9131.035286Yes-
PSMC1 5700 140.8401.018137Yes-

Interactions (72)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
ACTB 60 FBL 2091 pp -- int.I2D: MINT
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMC1 5700 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
RPL6 6128 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMC1 5700 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
PSMC1 5700 PHB2 11331 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB2 5690 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACTB 60 GTF2A1 2957 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core
GTF2A1 2957 SMARCA4 6597 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
RPS3A 6189 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
CAD 790 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RPSA 3921 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACTB 60 RPL6 6128 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
ACTB 60 SMARCA4 6597 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct, BCI, HPRD;
int.HPRD: in vitro, in vivo
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 SMARCA4 6597 pp -- int.I2D: BioGrid
RPS3A 6189 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMC1 5700 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast

Related GO terms (369)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.32e-161.20e-116.32092265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.68e-152.43e-116.21392270
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.85e-154.11e-116.13392274
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.28e-157.62e-116.03892379
GO:0006521regulation of cellular amino acid metabolic process1.20e-141.73e-106.52881750
GO:0016032viral process2.36e-143.40e-103.9191455534
GO:0016071mRNA metabolic process3.48e-145.01e-104.8311131223
GO:0000502proteasome complex4.24e-146.12e-106.31481758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest9.74e-141.40e-096.17281964
GO:0016070RNA metabolic process1.07e-131.55e-094.6831132247
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.61e-133.77e-096.00282072
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.67e-135.29e-095.94382075
GO:0010467gene expression5.18e-137.48e-093.5941459669
GO:0000082G1/S transition of mitotic cell cycle1.86e-122.69e-085.123932149
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.99e-122.87e-085.64982192
GO:0005829cytosol1.19e-111.71e-072.209201322496
GO:0000209protein polyubiquitination1.32e-111.91e-075.314820116
GO:0022624proteasome accessory complex6.24e-119.00e-077.4075817
GO:0042981regulation of apoptotic process1.06e-101.52e-064.943824150
GO:0034641cellular nitrogen compound metabolic process3.02e-104.35e-064.754820171
GO:0005654nucleoplasm3.35e-104.84e-062.90014761082
GO:0000278mitotic cell cycle4.35e-106.27e-063.8831048391
GO:0043066negative regulation of apoptotic process9.55e-101.38e-053.7661031424
GO:0070062extracellular vesicular exosome1.33e-091.91e-052.113181042400
GO:0005838proteasome regulatory particle3.44e-094.96e-057.5874712
GO:0016020membrane9.79e-091.41e-042.36415901681
GO:0043234protein complex4.89e-077.05e-033.775718295
GO:0006915apoptotic process2.77e-063.99e-023.056833555
GO:0005839proteasome core complex3.69e-065.32e-026.5873818
GO:0004298threonine-type endopeptidase activity4.38e-066.31e-026.5093819
GO:0043044ATP-dependent chromatin remodeling7.96e-061.15e-016.2343423
GO:0031492nucleosomal DNA binding1.31e-051.89e-016.0023427
GO:0006414translational elongation1.85e-052.66e-014.63341393
GO:0005730nucleolus3.90e-055.62e-011.95111691641
GO:0005634nucleus3.93e-055.67e-011.188181364559
GO:0044822poly(A) RNA binding4.08e-055.88e-012.2989491056
GO:0030957Tat protein binding4.31e-056.21e-017.587236
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.02e-041.00e+005.0293553
GO:0044281small molecule metabolic process1.19e-041.00e+002.1009581211
GO:0003723RNA binding2.62e-041.00e+003.076520342
GO:0019083viral transcription3.59e-041.00e+004.41731081
GO:0017025TBP-class protein binding3.86e-041.00e+006.0852317
GO:0006415translational termination4.43e-041.00e+004.31431087
GO:0001649osteoblast differentiation5.22e-041.00e+004.2343692
GO:0005515protein binding5.37e-041.00e+000.864191846024
GO:0006412translation6.12e-041.00e+003.327420230
GO:0036464cytoplasmic ribonucleoprotein granule6.52e-041.00e+005.7132422
GO:0005844polysome7.14e-041.00e+005.6492423
GO:0006614SRP-dependent cotranslational protein targeting to membrane7.46e-041.00e+004.057310104
GO:0030529ribonucleoprotein complex9.26e-041.00e+003.95038112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay9.74e-041.00e+003.924311114
GO:0019058viral life cycle9.99e-041.00e+003.912313115
GO:0044267cellular protein metabolic process1.16e-031.00e+002.605529474
GO:0033572transferrin transport1.22e-031.00e+005.2652530
GO:0000790nuclear chromatin1.39e-031.00e+003.74639129
GO:0006413translational initiation1.46e-031.00e+003.724317131
GO:0006200ATP catabolic process1.49e-031.00e+002.982415292
GO:0003735structural constituent of ribosome1.65e-031.00e+003.659310137
GO:0002842positive regulation of T cell mediated immune response to tumor cell1.73e-031.00e+009.172111
GO:0048291isotype switching to IgG isotypes1.73e-031.00e+009.172111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity1.73e-031.00e+009.172111
GO:0070335aspartate binding1.73e-031.00e+009.172111
GO:1990259histone-glutamine methyltransferase activity1.73e-031.00e+009.172111
GO:1990258histone glutamine methylation1.73e-031.00e+009.172111
GO:0004151dihydroorotase activity1.73e-031.00e+009.172111
GO:0004070aspartate carbamoyltransferase activity1.73e-031.00e+009.172111
GO:0016074snoRNA metabolic process1.73e-031.00e+009.172111
GO:0002368B cell cytokine production1.73e-031.00e+009.172111
GO:0016887ATPase activity1.76e-031.00e+003.62837140
GO:0022627cytosolic small ribosomal subunit2.06e-031.00e+004.8872439
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.81e-031.00e+003.39137165
GO:0005925focal adhesion3.38e-031.00e+002.657419366
GO:0035887aortic smooth muscle cell differentiation3.46e-031.00e+008.172112
GO:0006407rRNA export from nucleus3.46e-031.00e+008.172112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)3.46e-031.00e+008.172112
GO:0005055laminin receptor activity3.46e-031.00e+008.172112
GO:0007127meiosis I3.46e-031.00e+008.172112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis3.46e-031.00e+008.172112
GO:0070409carbamoyl phosphate biosynthetic process3.46e-031.00e+008.172112
GO:0003725double-stranded RNA binding3.63e-031.00e+004.4722552
GO:0002039p53 binding4.05e-031.00e+004.3912755
GO:0010424DNA methylation on cytosine within a CG sequence5.19e-031.00e+007.587113
GO:1900126negative regulation of hyaluronan biosynthetic process5.19e-031.00e+007.587123
GO:0006458'de novo' protein folding5.19e-031.00e+007.587113
GO:0001832blastocyst growth5.19e-031.00e+007.587113
GO:0007403glial cell fate determination5.19e-031.00e+007.587113
GO:0030135coated vesicle5.19e-031.00e+007.587113
GO:0005726perichromatin fibrils5.19e-031.00e+007.587113
GO:0044205'de novo' UMP biosynthetic process5.19e-031.00e+007.587113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process5.19e-031.00e+007.587113
GO:0071439clathrin complex5.19e-031.00e+007.587123
GO:0003697single-stranded DNA binding6.13e-031.00e+004.0852568
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.92e-031.00e+007.172114
GO:003068690S preribosome6.92e-031.00e+007.172114
GO:0032051clathrin light chain binding6.92e-031.00e+007.172114
GO:0019788NEDD8 ligase activity6.92e-031.00e+007.172114
GO:0001652granular component6.92e-031.00e+007.172114
GO:0031428box C/D snoRNP complex6.92e-031.00e+007.172114
GO:0060318definitive erythrocyte differentiation6.92e-031.00e+007.172114
GO:0006543glutamine catabolic process6.92e-031.00e+007.172114
GO:0001835blastocyst hatching6.92e-031.00e+007.172124
GO:0031467Cul7-RING ubiquitin ligase complex6.92e-031.00e+007.172114
GO:1903077negative regulation of protein localization to plasma membrane6.92e-031.00e+007.172114
GO:0001889liver development7.79e-031.00e+003.9052477
GO:0003407neural retina development8.64e-031.00e+006.850115
GO:0051414response to cortisol8.64e-031.00e+006.850115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex8.64e-031.00e+006.850135
GO:0005672transcription factor TFIIA complex8.64e-031.00e+006.850115
GO:2000001regulation of DNA damage checkpoint8.64e-031.00e+006.850115
GO:0048562embryonic organ morphogenesis8.64e-031.00e+006.850115
GO:0031461cullin-RING ubiquitin ligase complex8.64e-031.00e+006.850115
GO:0043248proteasome assembly8.64e-031.00e+006.850115
GO:0046696lipopolysaccharide receptor complex8.64e-031.00e+006.850115
GO:0030891VCB complex8.64e-031.00e+006.850125
GO:0033600negative regulation of mammary gland epithelial cell proliferation8.64e-031.00e+006.850115
GO:0000730DNA recombinase assembly8.64e-031.00e+006.850115
GO:0048730epidermis morphogenesis8.64e-031.00e+006.850115
GO:0047485protein N-terminus binding9.64e-031.00e+003.7462586
GO:0002181cytoplasmic translation1.04e-021.00e+006.587116
GO:0003688DNA replication origin binding1.04e-021.00e+006.587126
GO:0030130clathrin coat of trans-Golgi network vesicle1.04e-021.00e+006.587136
GO:0060744mammary gland branching involved in thelarche1.04e-021.00e+006.587116
GO:0006346methylation-dependent chromatin silencing1.04e-021.00e+006.587116
GO:0030118clathrin coat1.04e-021.00e+006.587126
GO:0031466Cul5-RING ubiquitin ligase complex1.04e-021.00e+006.587116
GO:0046134pyrimidine nucleoside biosynthetic process1.04e-021.00e+006.587116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.04e-021.00e+006.587116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis1.04e-021.00e+006.587116
GO:0016363nuclear matrix1.07e-021.00e+003.66421291
GO:0042470melanosome1.07e-021.00e+003.6642991
GO:0000028ribosomal small subunit assembly1.21e-021.00e+006.365117
GO:0031462Cul2-RING ubiquitin ligase complex1.21e-021.00e+006.365127
GO:0033180proton-transporting V-type ATPase, V1 domain1.21e-021.00e+006.365127
GO:0030132clathrin coat of coated pit1.21e-021.00e+006.365127
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.38e-021.00e+006.172128
GO:0070688MLL5-L complex1.38e-021.00e+006.172118
GO:0070182DNA polymerase binding1.38e-021.00e+006.172128
GO:0045116protein neddylation1.38e-021.00e+006.172128
GO:0019773proteasome core complex, alpha-subunit complex1.38e-021.00e+006.172148
GO:0051604protein maturation1.38e-021.00e+006.172118
GO:0014075response to amine1.55e-021.00e+006.002119
GO:0008494translation activator activity1.55e-021.00e+006.002119
GO:0006228UTP biosynthetic process1.55e-021.00e+006.002119
GO:0031000response to caffeine1.55e-021.00e+006.002129
GO:0005819spindle1.60e-021.00e+003.36527112
GO:0019901protein kinase binding1.69e-021.00e+002.449321317
GO:0010569regulation of double-strand break repair via homologous recombination1.72e-021.00e+005.8501110
GO:0043032positive regulation of macrophage activation1.72e-021.00e+005.8501110
GO:0070307lens fiber cell development1.72e-021.00e+005.8501210
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway1.72e-021.00e+005.8501110
GO:0032727positive regulation of interferon-alpha production1.89e-021.00e+005.7131111
GO:0031571mitotic G1 DNA damage checkpoint1.89e-021.00e+005.7131411
GO:0045120pronucleus1.89e-021.00e+005.7131211
GO:0043923positive regulation by host of viral transcription1.89e-021.00e+005.7131211
GO:0071564npBAF complex1.89e-021.00e+005.7131311
GO:00709353'-UTR-mediated mRNA stabilization2.06e-021.00e+005.5871212
GO:0071565nBAF complex2.06e-021.00e+005.5871312
GO:0005524ATP binding2.09e-021.00e+001.4156601298
GO:0060766negative regulation of androgen receptor signaling pathway2.23e-021.00e+005.4721113
GO:0005662DNA replication factor A complex2.23e-021.00e+005.4721113
GO:0030234enzyme regulator activity2.23e-021.00e+005.4721313
GO:0001530lipopolysaccharide binding2.23e-021.00e+005.4721313
GO:0008266poly(U) RNA binding2.23e-021.00e+005.4721113
GO:0051131chaperone-mediated protein complex assembly2.23e-021.00e+005.4721113
GO:0035267NuA4 histone acetyltransferase complex2.40e-021.00e+005.3651414
GO:0060347heart trabecula formation2.40e-021.00e+005.3651114
GO:0030902hindbrain development2.57e-021.00e+005.2651115
GO:0042026protein refolding2.57e-021.00e+005.2651215
GO:0046034ATP metabolic process2.57e-021.00e+005.2651115
GO:0046961proton-transporting ATPase activity, rotational mechanism2.57e-021.00e+005.2651315
GO:0016514SWI/SNF complex2.57e-021.00e+005.2651315
GO:0060749mammary gland alveolus development2.57e-021.00e+005.2651215
GO:0061024membrane organization2.59e-021.00e+002.99227145
GO:0042176regulation of protein catabolic process2.74e-021.00e+005.1721316
GO:0050998nitric-oxide synthase binding2.74e-021.00e+005.1721116
GO:0010243response to organonitrogen compound2.91e-021.00e+005.0851317
GO:0006337nucleosome disassembly2.91e-021.00e+005.0851317
GO:0006541glutamine metabolic process2.91e-021.00e+005.0851117
GO:0003746translation elongation factor activity2.91e-021.00e+005.0851317
GO:0050870positive regulation of T cell activation2.91e-021.00e+005.0851117
GO:0070577lysine-acetylated histone binding2.91e-021.00e+005.0851117
GO:0035861site of double-strand break3.08e-021.00e+005.0021118
GO:0007088regulation of mitosis3.08e-021.00e+005.0021118
GO:0017144drug metabolic process3.08e-021.00e+005.0021118
GO:0015078hydrogen ion transmembrane transporter activity3.24e-021.00e+004.9241319
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process3.24e-021.00e+004.9241119
GO:0048863stem cell differentiation3.24e-021.00e+004.9241119
GO:0032733positive regulation of interleukin-10 production3.24e-021.00e+004.9241119
GO:0005719nuclear euchromatin3.24e-021.00e+004.9241219
GO:2000134negative regulation of G1/S transition of mitotic cell cycle3.41e-021.00e+004.8501220
GO:0005680anaphase-promoting complex3.41e-021.00e+004.8501420
GO:0006298mismatch repair3.41e-021.00e+004.8501320
GO:0042100B cell proliferation3.58e-021.00e+004.7801121
GO:0000718nucleotide-excision repair, DNA damage removal3.58e-021.00e+004.7801421
GO:0071364cellular response to epidermal growth factor stimulus3.58e-021.00e+004.7801121
GO:0032201telomere maintenance via semi-conservative replication3.58e-021.00e+004.7801521
GO:0000792heterochromatin3.75e-021.00e+004.7131222
GO:0006206pyrimidine nucleobase metabolic process3.75e-021.00e+004.7131222
GO:0006297nucleotide-excision repair, DNA gap filling3.75e-021.00e+004.7131322
GO:0033574response to testosterone3.75e-021.00e+004.7131222
GO:0030863cortical cytoskeleton3.75e-021.00e+004.7131122
GO:0031625ubiquitin protein ligase binding3.77e-021.00e+002.696214178
GO:0031463Cul3-RING ubiquitin ligase complex3.91e-021.00e+004.6491323
GO:0043236laminin binding3.91e-021.00e+004.6491123
GO:0006513protein monoubiquitination3.91e-021.00e+004.6491123
GO:0001105RNA polymerase II transcription coactivator activity4.08e-021.00e+004.5871124
GO:0043388positive regulation of DNA binding4.08e-021.00e+004.5871124
GO:0000722telomere maintenance via recombination4.25e-021.00e+004.5281525
GO:0042113B cell activation4.25e-021.00e+004.5281225
GO:0032735positive regulation of interleukin-12 production4.25e-021.00e+004.5281125
GO:0070979protein K11-linked ubiquitination4.41e-021.00e+004.4721626
GO:0015991ATP hydrolysis coupled proton transport4.41e-021.00e+004.4721426
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia4.41e-021.00e+004.4721326
GO:0003730mRNA 3'-UTR binding4.41e-021.00e+004.4721226
GO:0030177positive regulation of Wnt signaling pathway4.58e-021.00e+004.4171327
GO:0030331estrogen receptor binding4.58e-021.00e+004.4171227
GO:0043022ribosome binding4.58e-021.00e+004.4171327
GO:0030669clathrin-coated endocytic vesicle membrane4.75e-021.00e+004.3651428
GO:0019894kinesin binding4.75e-021.00e+004.3651128
GO:0019005SCF ubiquitin ligase complex4.91e-021.00e+004.3141129
GO:0015992proton transport4.91e-021.00e+004.3141329
GO:0006271DNA strand elongation involved in DNA replication5.08e-021.00e+004.2651730
GO:0035116embryonic hindlimb morphogenesis5.08e-021.00e+004.2651130
GO:0031623receptor internalization5.24e-021.00e+004.2181231
GO:0007094mitotic spindle assembly checkpoint5.24e-021.00e+004.2181431
GO:0051701interaction with host5.41e-021.00e+004.1721432
GO:0032588trans-Golgi network membrane5.73e-021.00e+004.0851234
GO:0008094DNA-dependent ATPase activity5.73e-021.00e+004.0851234
GO:0008033tRNA processing5.73e-021.00e+004.0851134
GO:0001895retina homeostasis5.73e-021.00e+004.0851134
GO:0005876spindle microtubule5.73e-021.00e+004.0851234
GO:0007067mitotic nuclear division5.84e-021.00e+002.346214227
GO:0034332adherens junction organization6.06e-021.00e+004.0021136
GO:0090382phagosome maturation6.06e-021.00e+004.0021536
GO:0032755positive regulation of interleukin-6 production6.06e-021.00e+004.0021236
GO:0051084'de novo' posttranslational protein folding6.22e-021.00e+003.9631437
GO:0006284base-excision repair6.22e-021.00e+003.9631337
GO:0018107peptidyl-threonine phosphorylation6.22e-021.00e+003.9631437
GO:0003713transcription coactivator activity6.30e-021.00e+002.283210237
GO:0005902microvillus6.39e-021.00e+003.9241238
GO:0070527platelet aggregation6.39e-021.00e+003.9241238
GO:0050681androgen receptor binding6.39e-021.00e+003.9241338
GO:0000781chromosome, telomeric region6.55e-021.00e+003.8871339
GO:0032729positive regulation of interferon-gamma production6.55e-021.00e+003.8871239
GO:0007595lactation6.55e-021.00e+003.8871239
GO:0043195terminal bouton6.88e-021.00e+003.8151141
GO:0042110T cell activation7.04e-021.00e+003.7801342
GO:0030136clathrin-coated vesicle7.04e-021.00e+003.7801442
GO:0006892post-Golgi vesicle-mediated transport7.20e-021.00e+003.7461343
GO:0014070response to organic cyclic compound7.20e-021.00e+003.7461443
GO:0021762substantia nigra development7.36e-021.00e+003.7131244
GO:0015030Cajal body7.36e-021.00e+003.7131344
GO:0045727positive regulation of translation7.36e-021.00e+003.7131344
GO:0006281DNA repair7.45e-021.00e+002.144218261
GO:0043966histone H3 acetylation7.52e-021.00e+003.6801145
GO:0006283transcription-coupled nucleotide-excision repair7.68e-021.00e+003.6491746
GO:0030216keratinocyte differentiation7.84e-021.00e+003.6181147
GO:0019827stem cell maintenance7.84e-021.00e+003.6181147
GO:0000902cell morphogenesis8.16e-021.00e+003.5581249
GO:0030900forebrain development8.16e-021.00e+003.5581249
GO:0022625cytosolic large ribosomal subunit8.16e-021.00e+003.5581649
GO:0035690cellular response to drug8.16e-021.00e+003.5581249
GO:0003684damaged DNA binding8.16e-021.00e+003.5581749
GO:0005743mitochondrial inner membrane8.26e-021.00e+002.05828277
GO:0019899enzyme binding8.26e-021.00e+002.058212277
GO:0006986response to unfolded protein8.32e-021.00e+003.5281250
GO:0031100organ regeneration8.32e-021.00e+003.5281450
GO:0005905coated pit8.32e-021.00e+003.5281350
GO:0006879cellular iron ion homeostasis8.48e-021.00e+003.5001451
GO:0004386helicase activity8.64e-021.00e+003.4721252
GO:0045216cell-cell junction organization8.96e-021.00e+003.4171254
GO:0002244hematopoietic progenitor cell differentiation8.96e-021.00e+003.4171154
GO:0000724double-strand break repair via homologous recombination9.12e-021.00e+003.3911355
GO:0001570vasculogenesis9.28e-021.00e+003.3651156
GO:0000723telomere maintenance9.28e-021.00e+003.3651656
GO:0012505endomembrane system9.28e-021.00e+003.3651256
GO:0051087chaperone binding9.75e-021.00e+003.2901659
GO:0042995cell projection9.90e-021.00e+003.2651660
GO:0006302double-strand break repair1.02e-011.00e+003.2181462
GO:0019903protein phosphatase binding1.02e-011.00e+003.2181462
GO:0030141secretory granule1.02e-011.00e+003.2181262
GO:0006338chromatin remodeling1.08e-011.00e+003.1281566
GO:0005813centrosome1.09e-011.00e+001.823214326
GO:0006368transcription elongation from RNA polymerase II promoter1.10e-011.00e+003.1061667
GO:0006289nucleotide-excision repair1.12e-011.00e+003.08511168
GO:0034329cell junction assembly1.12e-011.00e+003.0851168
GO:0055086nucleobase-containing small molecule metabolic process1.15e-011.00e+003.0431270
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.21e-011.00e+002.9631674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.22e-011.00e+002.9431275
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.25e-011.00e+002.9051777
GO:0071013catalytic step 2 spliceosome1.27e-011.00e+002.8871478
GO:0007565female pregnancy1.27e-011.00e+002.8871178
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.30e-011.00e+002.8501380
GO:0001726ruffle1.30e-011.00e+002.8501480
GO:0005681spliceosomal complex1.34e-011.00e+002.7971483
GO:0006898receptor-mediated endocytosis1.36e-011.00e+002.7801384
GO:0050821protein stabilization1.42e-011.00e+002.7131288
GO:0016605PML body1.42e-011.00e+002.7131388
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.45e-011.00e+002.6801790
GO:0006928cellular component movement1.46e-011.00e+002.6641791
GO:0005200structural constituent of cytoskeleton1.46e-011.00e+002.6641891
GO:0071456cellular response to hypoxia1.48e-011.00e+002.6491692
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.48e-011.00e+002.6491592
GO:0051082unfolded protein binding1.49e-011.00e+002.6331593
GO:0006364rRNA processing1.51e-011.00e+002.6181694
GO:0045892negative regulation of transcription, DNA-templated1.60e-011.00e+001.482215413
GO:0014069postsynaptic density1.67e-011.00e+002.45813105
GO:0030308negative regulation of cell growth1.74e-011.00e+002.39116110
GO:0015630microtubule cytoskeleton1.74e-011.00e+002.39114110
GO:0072562blood microparticle1.76e-011.00e+002.37813111
GO:0006325chromatin organization1.86e-011.00e+002.29015118
GO:0007219Notch signaling pathway1.89e-011.00e+002.26515120
GO:0006260DNA replication1.90e-011.00e+002.25319121
GO:0006511ubiquitin-dependent protein catabolic process1.97e-011.00e+002.19515126
GO:0031982vesicle2.04e-011.00e+002.13919131
GO:0042802identical protein binding2.04e-011.00e+001.253220484
GO:0007507heart development2.15e-011.00e+002.05317139
GO:0008286insulin receptor signaling pathway2.19e-011.00e+002.02217142
GO:0006457protein folding2.21e-011.00e+002.01217143
GO:0010628positive regulation of gene expression2.25e-011.00e+001.98215146
GO:0005615extracellular space2.29e-011.00e+000.855317957
GO:0005198structural molecule activity2.30e-011.00e+001.94315150
GO:0005769early endosome2.33e-011.00e+001.92412152
GO:0046777protein autophosphorylation2.41e-011.00e+001.86817158
GO:0000398mRNA splicing, via spliceosome2.49e-011.00e+001.81518164
GO:0030424axon2.51e-011.00e+001.79714166
GO:0006886intracellular protein transport2.58e-011.00e+001.75415171
GO:0004672protein kinase activity2.66e-011.00e+001.70516177
GO:0003714transcription corepressor activity2.67e-011.00e+001.69618178
GO:0032403protein complex binding2.73e-011.00e+001.657110183
GO:0006367transcription initiation from RNA polymerase II promoter2.75e-011.00e+001.64918184
GO:0003924GTPase activity2.91e-011.00e+001.550112197
GO:0005765lysosomal membrane2.99e-011.00e+001.50715203
GO:0006184GTP catabolic process3.12e-011.00e+001.431112214
GO:0005737cytoplasm3.19e-011.00e+000.29381103767
GO:0005759mitochondrial matrix3.29e-011.00e+001.339114228
GO:0008380RNA splicing3.29e-011.00e+001.339111228
GO:0008134transcription factor binding3.45e-011.00e+001.25318242
GO:0043025neuronal cell body3.49e-011.00e+001.23619245
GO:0004842ubiquitin-protein transferase activity3.60e-011.00e+001.17816255
GO:0000166nucleotide binding3.65e-011.00e+001.15515259
GO:0006357regulation of transcription from RNA polymerase II promoter3.70e-011.00e+001.12818264
GO:0043065positive regulation of apoptotic process3.75e-011.00e+001.106110268
GO:0030198extracellular matrix organization3.91e-011.00e+001.02814283
GO:0005856cytoskeleton3.99e-011.00e+000.987112291
GO:0016567protein ubiquitination4.04e-011.00e+000.96815295
GO:0030154cell differentiation4.10e-011.00e+000.93915301
GO:0005525GTP binding4.19e-011.00e+000.896112310
GO:0043231intracellular membrane-bounded organelle4.28e-011.00e+000.85919318
GO:0007411axon guidance4.29e-011.00e+000.855113319
GO:0008283cell proliferation4.38e-011.00e+000.815114328
GO:0007155cell adhesion4.77e-011.00e+000.64516369
GO:0006508proteolysis4.85e-011.00e+000.61019378
GO:0046982protein heterodimerization activity4.87e-011.00e+000.602113380
GO:0009986cell surface5.07e-011.00e+000.521111402
GO:0006366transcription from RNA polymerase II promoter5.22e-011.00e+000.461110419
GO:0006355regulation of transcription, DNA-templated5.24e-011.00e+000.211218997
GO:0008270zinc ion binding5.24e-011.00e+000.211212997
GO:0005739mitochondrion5.24e-011.00e+000.209228998
GO:0055085transmembrane transport5.35e-011.00e+000.407110435
GO:0007596blood coagulation5.52e-011.00e+000.343118455
GO:0045893positive regulation of transcription, DNA-templated5.70e-011.00e+000.271113478
GO:0000122negative regulation of transcription from RNA polymerase II promoter6.35e-011.00e+000.017116570
GO:0003677DNA binding6.36e-011.00e+00-0.0782281218
GO:0045087innate immune response6.52e-011.00e+00-0.047124596
GO:0005886plasma membrane6.79e-011.00e+00-0.1624452582
GO:0006351transcription, DNA-templated7.30e-011.00e+00-0.3262311446
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.55e-011.00e+00-0.452119789
GO:0016021integral component of membrane9.75e-011.00e+00-1.7811271982