meta-reg-snw-9134
Interacting subnets
| Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
|---|---|---|---|---|---|---|---|
| int-snw-1455 | wolf-screen-ratio-mammosphere-adherent | 0.994 | 6.85e-18 | 6.35e-04 | 1.46e-02 | 16 | 15 |
| reg-snw-9134 | wolf-screen-ratio-mammosphere-adherent | 0.872 | 1.64e-07 | 1.14e-03 | 2.40e-03 | 8 | 7 |
| int-snw-10209 | wolf-screen-ratio-mammosphere-adherent | 0.936 | 1.51e-15 | 2.42e-03 | 3.95e-02 | 14 | 13 |
| int-snw-3838 | wolf-screen-ratio-mammosphere-adherent | 0.930 | 2.46e-15 | 2.73e-03 | 4.30e-02 | 10 | 8 |
| int-snw-3305 | wolf-screen-ratio-mammosphere-adherent | 0.942 | 8.57e-16 | 2.11e-03 | 3.57e-02 | 23 | 22 |
Genes (45)
| Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | Transcription factor | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
|---|---|---|---|---|---|---|---|---|
| CCNE2 | 9134 | 5 | -0.164 | 0.872 | 126 | TF | - | - |
| PSMA3 | 5684 | 90 | 0.533 | 0.815 | 238 | - | Yes | - |
| DDX18 | 8886 | 25 | 0.660 | 1.013 | 215 | TF | Yes | - |
| PSMA2 | 5683 | 112 | 1.093 | 1.106 | 108 | - | Yes | - |
| TP53 | 7157 | 23 | 0.432 | 0.833 | 665 | TF | - | - |
| RRM1 | 6240 | 15 | 0.587 | 0.872 | 117 | - | Yes | - |
| LPIN3 | 64900 | 8 | -0.625 | 0.994 | 39 | - | - | Yes |
| ATP6V1B2 | 526 | 53 | 0.881 | 1.076 | 278 | - | - | - |
| ADH5 | 128 | 16 | 0.633 | 0.994 | 43 | - | Yes | - |
| RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | - | Yes | - |
| PSMD2 | 5708 | 17 | 0.463 | 0.961 | 386 | - | Yes | - |
| RSL24D1 | 51187 | 38 | 1.300 | 1.020 | 59 | - | Yes | - |
| CCNA2 | 890 | 54 | 0.550 | 0.973 | 246 | TF | Yes | - |
| EIF2S2 | 8894 | 39 | 1.075 | 0.940 | 103 | - | Yes | - |
| IARS | 3376 | 7 | 0.399 | 0.936 | 175 | - | Yes | - |
| EEF2 | 1938 | 64 | 0.890 | 1.043 | 301 | - | Yes | - |
| RPS11 | 6205 | 62 | 0.993 | 1.113 | 175 | - | Yes | - |
| EIF1 | 10209 | 7 | -0.215 | 0.936 | 64 | - | - | - |
| EFTUD2 | 9343 | 93 | 0.883 | 0.956 | 108 | - | Yes | - |
| TUBG1 | 7283 | 98 | 0.974 | 0.973 | 91 | - | Yes | - |
| PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | TF | Yes | - |
| HSPD1 | 3329 | 70 | 0.913 | 1.035 | 325 | - | Yes | - |
| KPNB1 | 3837 | 17 | 0.613 | 1.017 | 296 | - | Yes | - |
| ITK | 3702 | 15 | 0.602 | 0.950 | 39 | - | Yes | - |
| CSNK1G2 | 1455 | 8 | -0.084 | 0.994 | 90 | - | - | - |
| RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | TF | Yes | - |
| RPL8 | 6132 | 24 | 0.778 | 0.874 | 234 | TF | Yes | - |
| HNRNPC | 3183 | 108 | 1.812 | 0.973 | 181 | - | Yes | - |
| PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | - | Yes | - |
| PSMA1 | 5682 | 100 | 0.996 | 0.878 | 152 | - | Yes | - |
| OGDH | 4967 | 72 | 0.847 | 0.802 | 126 | - | Yes | - |
| RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | - | Yes | - |
| PGD | 5226 | 89 | 1.201 | 1.106 | 152 | - | Yes | - |
| HSPA1L | 3305 | 34 | -0.414 | 0.942 | 125 | - | - | Yes |
| ACO2 | 50 | 65 | 1.000 | 1.076 | 191 | - | Yes | - |
| RUVBL1 | 8607 | 95 | 0.720 | 0.973 | 469 | TF | Yes | - |
| PSMD13 | 5719 | 56 | 0.848 | 0.801 | 114 | TF | Yes | - |
| PSMD3 | 5709 | 100 | 0.986 | 1.106 | 201 | TF | Yes | - |
| CLTC | 1213 | 56 | 0.884 | 1.138 | 247 | - | Yes | - |
| RPL14 | 9045 | 49 | 1.250 | 1.113 | 166 | - | Yes | - |
| PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | - | Yes | - |
| ACTB | 60 | 134 | 1.153 | 1.151 | 610 | - | Yes | - |
| KPNA2 | 3838 | 5 | 0.176 | 0.930 | 141 | TF | - | - |
| RUVBL2 | 10856 | 95 | 0.693 | 0.956 | 532 | TF | Yes | - |
| PSMD6 | 9861 | 79 | 0.848 | 0.878 | 143 | TF | Yes | - |
Interactions (194)
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
|---|---|---|---|---|---|---|
| PSMA3 | 5684 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core |
| PSMD11 | 5717 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG |
| RPS11 | 6205 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid |
| PSMD2 | 5708 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastLow |
| HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
| ADH5 | 128 | DDX18 | 8886 | pp | -- | int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast |
| EEF2 | 1938 | PGD | 5226 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA1 | 5682 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast |
| PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
| HSPA1L | 3305 | TP53 | 7157 | pp | -- | int.I2D: MINT, MINT_Mouse; int.Mint: MI:0915(physical association) |
| EEF2 | 1938 | HSPD1 | 3329 | pp | -- | int.I2D: YeastLow, YeastMedium |
| PSMD11 | 5717 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
| PSMA2 | 5683 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMA3 | 5684 | EIF1 | 10209 | pp | -- | int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Yeast |
| ACO2 | 50 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
| EFTUD2 | 9343 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
| EFTUD2 | 9343 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid |
| KPNB1 | 3837 | TP53 | 7157 | pp | -- | int.I2D: BioGrid, HPRD; int.HPRD: in vivo |
| KPNA2 | 3838 | EIF2S2 | 8894 | pd | > | reg.ITFP.txt: no annot |
| ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
| ACTB | 60 | RUVBL1 | 8607 | pp | -- | int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast |
| ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
| ACTB | 60 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
| PSMD2 | 5708 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastLow |
| PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
| CCNA2 | 890 | RUVBL1 | 8607 | pd | <> | reg.ITFP.txt: no annot |
| ATP6V1B2 | 526 | OGDH | 4967 | pp | -- | int.I2D: IntAct_Yeast |
| CLTC | 1213 | CSNK1G2 | 1455 | pp | -- | int.I2D: BioGrid_Yeast |
| IARS | 3376 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast |
| IARS | 3376 | EIF1 | 10209 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast |
| OGDH | 4967 | PSMD2 | 5708 | pp | -- | int.I2D: YeastLow |
| PSMA3 | 5684 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid |
| PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
| RPA2 | 6118 | TP53 | 7157 | pp | -- | int.Transfac: - |
| TP53 | 7157 | EIF2S2 | 8894 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
| PSMD2 | 5708 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
| ACO2 | 50 | HSPD1 | 3329 | pp | -- | int.I2D: IntAct_Yeast |
| OGDH | 4967 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
| ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
| PSMB2 | 5690 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
| KPNB1 | 3837 | DDX18 | 8886 | pp | -- | int.I2D: Krogan_NonCore, YeastLow |
| ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
| KPNB1 | 3837 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid |
| RRM1 | 6240 | TP53 | 7157 | pd | < | reg.pazar.txt: no annot; reg.oreganno.txt: no annot |
| CSNK1G2 | 1455 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid_Yeast, Yeast_Kinome |
| ADH5 | 128 | TP53 | 7157 | pp | -- | int.I2D: BioGrid |
| PSMA1 | 5682 | PSMD6 | 9861 | pd | < | reg.ITFP.txt: no annot |
| PSMA1 | 5682 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastMedium |
| PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
| CLTC | 1213 | RUVBL1 | 8607 | pp | -- | int.I2D: MINT_Worm, IntAct_Worm |
| ATP6V1B2 | 526 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
| ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
| PSMD2 | 5708 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastLow, BioGrid |
| ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
| HSPA1L | 3305 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid |
| PSMD11 | 5717 | TP53 | 7157 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, MINT, StelzlHigh, HPRD, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
| ACTB | 60 | CSNK1G2 | 1455 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
| ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
| CLTC | 1213 | EIF2S2 | 8894 | pp | -- | int.I2D: YeastLow |
| PSMA3 | 5684 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMD6 | 9861 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
| ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
| CSNK1G2 | 1455 | DDX18 | 8886 | pp | -- | int.I2D: BioGrid_Yeast, Yeast_Kinome |
| EEF2 | 1938 | TP53 | 7157 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo |
| PSMB2 | 5690 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| OGDH | 4967 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| CCNA2 | 890 | RRM1 | 6240 | pd | > | reg.ITFP.txt: no annot |
| OGDH | 4967 | PSMD6 | 9861 | pp | -- | int.I2D: YeastLow |
| RUVBL1 | 8607 | RUVBL2 | 10856 | pd | <> | reg.ITFP.txt: no annot |
| RUVBL1 | 8607 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association) |
| EEF2 | 1938 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
| PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
| ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
| EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
| OGDH | 4967 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
| OGDH | 4967 | RPL8 | 6132 | pp | -- | int.I2D: IntAct_Yeast |
| PSMD11 | 5717 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
| PSMA3 | 5684 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
| RPL8 | 6132 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
| PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
| HNRNPC | 3183 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
| PSMD3 | 5709 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
| PSMD3 | 5709 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
| RUVBL1 | 8607 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
| KPNB1 | 3837 | PSMA2 | 5683 | pp | -- | int.I2D: Krogan_NonCore, YeastLow |
| HNRNPC | 3183 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
| HNRNPC | 3183 | TP53 | 7157 | pd | < | reg.ITFP.txt: no annot |
| PSMD2 | 5708 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
| ADH5 | 128 | CSNK1G2 | 1455 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA3 | 5684 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow |
| ACO2 | 50 | PSMD2 | 5708 | pp | -- | int.I2D: YeastLow |
| RPL8 | 6132 | DDX18 | 8886 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA3 | 5684 | EFTUD2 | 9343 | pp | -- | int.I2D: BioGrid |
| PSMB2 | 5690 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
| OGDH | 4967 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| HSPD1 | 3329 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
| PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
| PSMD13 | 5719 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastHigh |
| PSMA3 | 5684 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core |
| RPL8 | 6132 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
| PSMD3 | 5709 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS |
| CLTC | 1213 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0914(association) |
| ACO2 | 50 | KPNB1 | 3837 | pp | -- | int.I2D: IntAct_Yeast |
| PSMA2 | 5683 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMB2 | 5690 | RPL8 | 6132 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| TUBG1 | 7283 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
| PSMA3 | 5684 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid |
| HSPD1 | 3329 | TP53 | 7157 | pp | -- | int.Intact: MI:0914(association) |
| RPL8 | 6132 | EIF1 | 10209 | pp | -- | int.I2D: YeastMedium |
| KPNA2 | 3838 | TP53 | 7157 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid |
| TUBG1 | 7283 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
| CCNA2 | 890 | TP53 | 7157 | pp | -- | int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro |
| ACTB | 60 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| RPS11 | 6205 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA1 | 5682 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
| PSMA1 | 5682 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd; int.HPRD: in vitro |
| ATP6V1B2 | 526 | RUVBL2 | 10856 | pp | -- | int.I2D: IntAct_Yeast |
| PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMD11 | 5717 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
| ITK | 3702 | KPNA2 | 3838 | pp | -- | int.I2D: BioGrid, HPRD, BIND; int.HPRD: in vitro, in vivo |
| RPSA | 3921 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| EEF2 | 1938 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
| OGDH | 4967 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
| PSMB7 | 5695 | PSMD6 | 9861 | pd | < | reg.ITFP.txt: no annot |
| PSMB7 | 5695 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct |
| PSMD11 | 5717 | EFTUD2 | 9343 | pd | > | reg.ITFP.txt: no annot |
| RUVBL1 | 8607 | PSMD6 | 9861 | pp | -- | int.I2D: YeastLow |
| KPNB1 | 3837 | PSMA1 | 5682 | pp | -- | int.I2D: YeastLow |
| ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
| DDX18 | 8886 | RSL24D1 | 51187 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast |
| CCNA2 | 890 | CCNE2 | 9134 | pd | <> | reg.ITFP.txt: no annot |
| ATP6V1B2 | 526 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
| PSMD11 | 5717 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
| ATP6V1B2 | 526 | IARS | 3376 | pp | -- | int.I2D: IntAct_Yeast |
| OGDH | 4967 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
| PSMB7 | 5695 | PSMD13 | 5719 | pd | < | reg.ITFP.txt: no annot |
| EEF2 | 1938 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMD13 | 5719 | RRM1 | 6240 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| KPNA2 | 3838 | RUVBL1 | 8607 | pd | <> | reg.ITFP.txt: no annot |
| IARS | 3376 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
| EEF2 | 1938 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast |
| ACO2 | 50 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
| PSMA3 | 5684 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| HSPA1L | 3305 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
| PSMB2 | 5690 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| ATP6V1B2 | 526 | LPIN3 | 64900 | pp | -- | int.I2D: IntAct_Yeast |
| KPNB1 | 3837 | PSMA3 | 5684 | pp | -- | int.I2D: YeastLow |
| PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| HSPA1L | 3305 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid |
| KPNB1 | 3837 | KPNA2 | 3838 | pp | -- | int.I2D: BioGrid, BIND_Mouse, IntAct_Fly, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: in vitro, yeast 2-hybrid; int.DIP: MI:0407(direct interaction) |
| PSMA3 | 5684 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
| HSPD1 | 3329 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
| EEF2 | 1938 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
| PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMD2 | 5708 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow |
| PSMA2 | 5683 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid |
| RRM1 | 6240 | CCNE2 | 9134 | pd | < | reg.ITFP.txt: no annot |
| HNRNPC | 3183 | KPNA2 | 3838 | pp | -- | int.Intact: MI:0915(physical association) |
| PSMD13 | 5719 | EIF1 | 10209 | pp | -- | int.I2D: IntAct_Yeast, BioGrid_Yeast, BIND_Yeast |
| PSMD11 | 5717 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG |
| IARS | 3376 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
| PSMD2 | 5708 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastLow, BioGrid, Krogan_Core |
| PSMD2 | 5708 | EIF1 | 10209 | pp | -- | int.I2D: IntAct_Yeast, BioGrid_Yeast, BIND_Yeast |
| PSMD3 | 5709 | PSMD13 | 5719 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core |
| EIF2S2 | 8894 | EIF1 | 10209 | pp | -- | int.I2D: BioGrid_Yeast |
| IARS | 3376 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| ACTB | 60 | ATP6V1B2 | 526 | pp | -- | int.I2D: BioGrid_Yeast |
| KPNB1 | 3837 | PSMD11 | 5717 | pp | -- | int.I2D: Krogan_NonCore |
| PSMD13 | 5719 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core |
| RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
| PSMD11 | 5717 | RRM1 | 6240 | pd | > | reg.ITFP.txt: no annot |
| PSMD2 | 5708 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
| CCNA2 | 890 | KPNA2 | 3838 | pd | <> | reg.ITFP.txt: no annot |
| PGD | 5226 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| KPNB1 | 3837 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid |
| PSMD2 | 5708 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
| RPS11 | 6205 | DDX18 | 8886 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid |
| PSMA2 | 5683 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid |
| PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| ACO2 | 50 | DDX18 | 8886 | pp | -- | int.I2D: YeastLow |
| CSNK1G2 | 1455 | LPIN3 | 64900 | pp | -- | int.I2D: BioGrid_Yeast, Yeast_Kinome |
| PSMD11 | 5717 | EIF2S2 | 8894 | pd | > | reg.ITFP.txt: no annot |
| PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
Related GO terms (547)
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
|---|---|---|---|---|---|---|---|
| GO:0005829 | cytosol | 9.88e-18 | 1.61e-13 | 2.224 | 33 | 125 | 2562 |
| GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.50e-17 | 2.45e-13 | 5.940 | 11 | 22 | 65 |
| GO:0016032 | viral process | 5.99e-17 | 9.78e-13 | 3.674 | 19 | 55 | 540 |
| GO:0006521 | regulation of cellular amino acid metabolic process | 8.22e-17 | 1.34e-12 | 6.181 | 10 | 21 | 50 |
| GO:0000502 | proteasome complex | 4.11e-16 | 6.71e-12 | 5.967 | 10 | 22 | 58 |
| GO:0016071 | mRNA metabolic process | 6.02e-16 | 9.83e-12 | 4.509 | 14 | 34 | 223 |
| GO:0005654 | nucleoplasm | 8.16e-16 | 1.33e-11 | 2.929 | 23 | 83 | 1095 |
| GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.39e-15 | 2.27e-11 | 5.802 | 10 | 24 | 65 |
| GO:0016070 | RNA metabolic process | 2.51e-15 | 4.10e-11 | 4.362 | 14 | 34 | 247 |
| GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.05e-15 | 4.98e-11 | 5.695 | 10 | 24 | 70 |
| GO:0010467 | gene expression | 3.05e-15 | 4.98e-11 | 3.365 | 19 | 58 | 669 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 4.75e-15 | 7.76e-11 | 5.635 | 10 | 23 | 73 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 5.15e-15 | 8.41e-11 | 4.859 | 12 | 33 | 150 |
| GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.49e-15 | 8.96e-11 | 5.615 | 10 | 24 | 74 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.33e-15 | 1.36e-10 | 5.558 | 10 | 23 | 77 |
| GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.09e-14 | 1.78e-10 | 5.521 | 10 | 25 | 79 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 6.64e-14 | 1.08e-09 | 5.270 | 10 | 23 | 94 |
| GO:0000278 | mitotic cell cycle | 8.74e-14 | 1.43e-09 | 3.773 | 15 | 52 | 398 |
| GO:0042981 | regulation of apoptotic process | 2.28e-13 | 3.72e-09 | 4.724 | 11 | 26 | 151 |
| GO:0000209 | protein polyubiquitination | 5.74e-13 | 9.37e-09 | 4.967 | 10 | 21 | 116 |
| GO:0034641 | cellular nitrogen compound metabolic process | 1.32e-12 | 2.15e-08 | 4.494 | 11 | 25 | 177 |
| GO:0070062 | extracellular vesicular exosome | 8.23e-11 | 1.34e-06 | 1.906 | 26 | 98 | 2516 |
| GO:0016020 | membrane | 1.39e-10 | 2.27e-06 | 2.192 | 22 | 80 | 1746 |
| GO:0022624 | proteasome accessory complex | 7.65e-10 | 1.25e-05 | 6.737 | 5 | 9 | 17 |
| GO:0005839 | proteasome core complex | 1.06e-09 | 1.72e-05 | 6.655 | 5 | 11 | 18 |
| GO:0043066 | negative regulation of apoptotic process | 1.36e-09 | 2.22e-05 | 3.329 | 12 | 30 | 433 |
| GO:0004298 | threonine-type endopeptidase activity | 1.90e-09 | 3.11e-05 | 6.503 | 5 | 11 | 20 |
| GO:0044281 | small molecule metabolic process | 2.29e-08 | 3.74e-04 | 2.251 | 17 | 57 | 1295 |
| GO:0005838 | proteasome regulatory particle | 2.46e-08 | 4.01e-04 | 6.918 | 4 | 7 | 12 |
| GO:0006915 | apoptotic process | 3.00e-08 | 4.90e-04 | 2.930 | 12 | 34 | 571 |
| GO:0044822 | poly(A) RNA binding | 6.66e-07 | 1.09e-02 | 2.236 | 14 | 50 | 1078 |
| GO:0019773 | proteasome core complex, alpha-subunit complex | 1.09e-06 | 1.77e-02 | 7.088 | 3 | 5 | 8 |
| GO:0005515 | protein binding | 1.12e-06 | 1.83e-02 | 0.966 | 33 | 172 | 6127 |
| GO:0006413 | translational initiation | 1.50e-06 | 2.45e-02 | 4.054 | 6 | 12 | 131 |
| GO:0006414 | translational elongation | 5.50e-06 | 8.98e-02 | 4.285 | 5 | 11 | 93 |
| GO:0035267 | NuA4 histone acetyltransferase complex | 6.98e-06 | 1.14e-01 | 6.280 | 3 | 4 | 14 |
| GO:0019058 | viral life cycle | 1.55e-05 | 2.53e-01 | 3.979 | 5 | 10 | 115 |
| GO:0006412 | translation | 4.26e-05 | 6.95e-01 | 3.211 | 6 | 15 | 235 |
| GO:0019083 | viral transcription | 7.19e-05 | 1.00e+00 | 4.163 | 4 | 8 | 81 |
| GO:0006415 | translational termination | 9.50e-05 | 1.00e+00 | 4.060 | 4 | 8 | 87 |
| GO:0005730 | nucleolus | 1.12e-04 | 1.00e+00 | 1.592 | 14 | 70 | 1684 |
| GO:0001649 | osteoblast differentiation | 1.34e-04 | 1.00e+00 | 3.933 | 4 | 6 | 95 |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.90e-04 | 1.00e+00 | 3.802 | 4 | 8 | 104 |
| GO:0000812 | Swr1 complex | 2.06e-04 | 1.00e+00 | 6.503 | 2 | 3 | 8 |
| GO:0005524 | ATP binding | 2.20e-04 | 1.00e+00 | 1.685 | 12 | 46 | 1354 |
| GO:0019901 | protein kinase binding | 2.32e-04 | 1.00e+00 | 2.766 | 6 | 21 | 320 |
| GO:0008139 | nuclear localization sequence binding | 2.64e-04 | 1.00e+00 | 6.333 | 2 | 2 | 9 |
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 2.70e-04 | 1.00e+00 | 3.670 | 4 | 10 | 114 |
| GO:0030529 | ribonucleoprotein complex | 2.70e-04 | 1.00e+00 | 3.670 | 4 | 8 | 114 |
| GO:0003684 | damaged DNA binding | 3.72e-04 | 1.00e+00 | 4.415 | 3 | 11 | 51 |
| GO:0044267 | cellular protein metabolic process | 3.78e-04 | 1.00e+00 | 2.359 | 7 | 24 | 495 |
| GO:0031571 | mitotic G1 DNA damage checkpoint | 4.02e-04 | 1.00e+00 | 6.043 | 2 | 3 | 11 |
| GO:0005759 | mitochondrial matrix | 4.36e-04 | 1.00e+00 | 2.960 | 5 | 12 | 233 |
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.40e-04 | 1.00e+00 | 4.333 | 3 | 5 | 54 |
| GO:0043968 | histone H2A acetylation | 4.82e-04 | 1.00e+00 | 5.918 | 2 | 3 | 12 |
| GO:0030234 | enzyme regulator activity | 5.69e-04 | 1.00e+00 | 5.802 | 2 | 3 | 13 |
| GO:0051087 | chaperone binding | 5.72e-04 | 1.00e+00 | 4.205 | 3 | 6 | 59 |
| GO:0003735 | structural constituent of ribosome | 6.04e-04 | 1.00e+00 | 3.363 | 4 | 8 | 141 |
| GO:0016887 | ATPase activity | 6.54e-04 | 1.00e+00 | 3.333 | 4 | 7 | 144 |
| GO:0006607 | NLS-bearing protein import into nucleus | 6.62e-04 | 1.00e+00 | 5.695 | 2 | 2 | 14 |
| GO:0031011 | Ino80 complex | 6.62e-04 | 1.00e+00 | 5.695 | 2 | 3 | 14 |
| GO:0042026 | protein refolding | 7.63e-04 | 1.00e+00 | 5.596 | 2 | 2 | 15 |
| GO:0042176 | regulation of protein catabolic process | 8.70e-04 | 1.00e+00 | 5.503 | 2 | 3 | 16 |
| GO:0003678 | DNA helicase activity | 1.23e-03 | 1.00e+00 | 5.255 | 2 | 3 | 19 |
| GO:0043234 | protein complex | 1.36e-03 | 1.00e+00 | 2.596 | 5 | 17 | 300 |
| GO:0043044 | ATP-dependent chromatin remodeling | 1.81e-03 | 1.00e+00 | 4.979 | 2 | 4 | 23 |
| GO:0005634 | nucleus | 1.95e-03 | 1.00e+00 | 0.789 | 23 | 131 | 4828 |
| GO:0008135 | translation factor activity, nucleic acid binding | 1.97e-03 | 1.00e+00 | 4.918 | 2 | 4 | 24 |
| GO:0000060 | protein import into nucleus, translocation | 1.97e-03 | 1.00e+00 | 4.918 | 2 | 4 | 24 |
| GO:0016363 | nuclear matrix | 2.07e-03 | 1.00e+00 | 3.564 | 3 | 11 | 92 |
| GO:0005844 | polysome | 2.14e-03 | 1.00e+00 | 4.859 | 2 | 4 | 25 |
| GO:0051082 | unfolded protein binding | 2.27e-03 | 1.00e+00 | 3.518 | 3 | 6 | 95 |
| GO:0019843 | rRNA binding | 2.50e-03 | 1.00e+00 | 4.748 | 2 | 3 | 27 |
| GO:0071339 | MLL1 complex | 2.50e-03 | 1.00e+00 | 4.748 | 2 | 3 | 27 |
| GO:0043967 | histone H4 acetylation | 2.68e-03 | 1.00e+00 | 4.695 | 2 | 3 | 28 |
| GO:0031492 | nucleosomal DNA binding | 2.68e-03 | 1.00e+00 | 4.695 | 2 | 4 | 28 |
| GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0018467 | formaldehyde dehydrogenase activity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0048291 | isotype switching to IgG isotypes | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0019521 | D-gluconate metabolic process | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0002368 | B cell cytokine production | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0051903 | S-(hydroxymethyl)glutathione dehydrogenase activity | 2.76e-03 | 1.00e+00 | 8.503 | 1 | 1 | 1 |
| GO:0003723 | RNA binding | 2.83e-03 | 1.00e+00 | 2.353 | 5 | 19 | 355 |
| GO:0006099 | tricarboxylic acid cycle | 2.88e-03 | 1.00e+00 | 4.645 | 2 | 3 | 29 |
| GO:0034644 | cellular response to UV | 3.50e-03 | 1.00e+00 | 4.503 | 2 | 5 | 32 |
| GO:0033572 | transferrin transport | 3.50e-03 | 1.00e+00 | 4.503 | 2 | 6 | 32 |
| GO:0006325 | chromatin organization | 4.71e-03 | 1.00e+00 | 3.145 | 3 | 4 | 123 |
| GO:0006284 | base-excision repair | 5.16e-03 | 1.00e+00 | 4.217 | 2 | 7 | 39 |
| GO:0022627 | cytosolic small ribosomal subunit | 5.16e-03 | 1.00e+00 | 4.217 | 2 | 3 | 39 |
| GO:0097252 | oligodendrocyte apoptotic process | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0045252 | oxoglutarate dehydrogenase complex | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 2 | 2 |
| GO:0003994 | aconitate hydratase activity | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0006407 | rRNA export from nucleus | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0061034 | olfactory bulb mitral cell layer development | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0090343 | positive regulation of cell aging | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0019322 | pentose biosynthetic process | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0051538 | 3 iron, 4 sulfur cluster binding | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:1901525 | negative regulation of macromitophagy | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0006428 | isoleucyl-tRNA aminoacylation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0002176 | male germ cell proliferation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0046294 | formaldehyde catabolic process | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0032633 | interleukin-4 production | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0004822 | isoleucine-tRNA ligase activity | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0005055 | laminin receptor activity | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0001865 | NK T cell differentiation | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0007127 | meiosis I | 5.51e-03 | 1.00e+00 | 7.503 | 1 | 1 | 2 |
| GO:0000790 | nuclear chromatin | 5.85e-03 | 1.00e+00 | 3.032 | 3 | 7 | 133 |
| GO:0006281 | DNA repair | 5.93e-03 | 1.00e+00 | 2.458 | 4 | 22 | 264 |
| GO:0032508 | DNA duplex unwinding | 5.97e-03 | 1.00e+00 | 4.110 | 2 | 4 | 42 |
| GO:0042110 | T cell activation | 6.25e-03 | 1.00e+00 | 4.076 | 2 | 3 | 43 |
| GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 6.53e-03 | 1.00e+00 | 4.043 | 2 | 2 | 44 |
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | 7.43e-03 | 1.00e+00 | 3.948 | 2 | 3 | 47 |
| GO:0022625 | cytosolic large ribosomal subunit | 8.05e-03 | 1.00e+00 | 3.888 | 2 | 5 | 49 |
| GO:0003743 | translation initiation factor activity | 8.05e-03 | 1.00e+00 | 3.888 | 2 | 4 | 49 |
| GO:0009263 | deoxyribonucleotide biosynthetic process | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:1900126 | negative regulation of hyaluronan biosynthetic process | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0006458 | 'de novo' protein folding | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0035033 | histone deacetylase regulator activity | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0002360 | T cell lineage commitment | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0009051 | pentose-phosphate shunt, oxidative branch | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0034103 | regulation of tissue remodeling | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0030135 | coated vesicle | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0009048 | dosage compensation by inactivation of X chromosome | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0018119 | peptidyl-cysteine S-nitrosylation | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0035794 | positive regulation of mitochondrial membrane permeability | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0071899 | negative regulation of estrogen receptor binding | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0051097 | negative regulation of helicase activity | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0005850 | eukaryotic translation initiation factor 2 complex | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0071733 | transcriptional activation by promoter-enhancer looping | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0071439 | clathrin complex | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 3 |
| GO:0006091 | generation of precursor metabolites and energy | 8.70e-03 | 1.00e+00 | 3.830 | 2 | 3 | 51 |
| GO:0040008 | regulation of growth | 8.70e-03 | 1.00e+00 | 3.830 | 2 | 3 | 51 |
| GO:0006986 | response to unfolded protein | 8.70e-03 | 1.00e+00 | 3.830 | 2 | 2 | 51 |
| GO:0006200 | ATP catabolic process | 9.54e-03 | 1.00e+00 | 2.259 | 4 | 14 | 303 |
| GO:0003725 | double-stranded RNA binding | 9.71e-03 | 1.00e+00 | 3.748 | 2 | 6 | 54 |
| GO:0002039 | p53 binding | 1.01e-02 | 1.00e+00 | 3.721 | 2 | 7 | 55 |
| GO:0008565 | protein transporter activity | 1.08e-02 | 1.00e+00 | 3.670 | 2 | 2 | 57 |
| GO:0030686 | 90S preribosome | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0019788 | NEDD8 ligase activity | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0051409 | response to nitrosative stress | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0006068 | ethanol catabolic process | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0043141 | ATP-dependent 5'-3' DNA helicase activity | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0002326 | B cell lineage commitment | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0071782 | endoplasmic reticulum tubular network | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0000212 | meiotic spindle organization | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0032051 | clathrin light chain binding | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0090403 | oxidative stress-induced premature senescence | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0006104 | succinyl-CoA metabolic process | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0031467 | Cul7-RING ubiquitin ligase complex | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0006610 | ribosomal protein import into nucleus | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:1903077 | negative regulation of protein localization to plasma membrane | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 1 | 4 |
| GO:0006302 | double-strand break repair | 1.27e-02 | 1.00e+00 | 3.548 | 2 | 8 | 62 |
| GO:0019903 | protein phosphatase binding | 1.30e-02 | 1.00e+00 | 3.525 | 2 | 4 | 63 |
| GO:0031625 | ubiquitin protein ligase binding | 1.33e-02 | 1.00e+00 | 2.596 | 3 | 13 | 180 |
| GO:0001940 | male pronucleus | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:2000001 | regulation of DNA damage checkpoint | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0043248 | proteasome assembly | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0004022 | alcohol dehydrogenase (NAD) activity | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0030891 | VCB complex | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 2 | 5 |
| GO:0005827 | polar microtubule | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0006734 | NADH metabolic process | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 2 | 5 |
| GO:0097371 | MDM2/MDM4 family protein binding | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0031461 | cullin-RING ubiquitin ligase complex | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0071169 | establishment of protein localization to chromatin | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0046696 | lipopolysaccharide receptor complex | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0006102 | isocitrate metabolic process | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0000730 | DNA recombinase assembly | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 3 | 5 |
| GO:0030976 | thiamine pyrophosphate binding | 1.37e-02 | 1.00e+00 | 6.181 | 1 | 1 | 5 |
| GO:0005737 | cytoplasm | 1.46e-02 | 1.00e+00 | 0.715 | 18 | 98 | 3976 |
| GO:0006310 | DNA recombination | 1.47e-02 | 1.00e+00 | 3.436 | 2 | 4 | 67 |
| GO:0003697 | single-stranded DNA binding | 1.55e-02 | 1.00e+00 | 3.394 | 2 | 9 | 69 |
| GO:0006289 | nucleotide-excision repair | 1.55e-02 | 1.00e+00 | 3.394 | 2 | 12 | 69 |
| GO:0000018 | regulation of DNA recombination | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0003688 | DNA replication origin binding | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0010666 | positive regulation of cardiac muscle cell apoptotic process | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0002309 | T cell proliferation involved in immune response | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0006101 | citrate metabolic process | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0030118 | clathrin coat | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0021695 | cerebellar cortex development | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0070245 | positive regulation of thymocyte apoptotic process | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0030130 | clathrin coat of trans-Golgi network vesicle | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0021860 | pyramidal neuron development | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0031466 | Cul5-RING ubiquitin ligase complex | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0030957 | Tat protein binding | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 4 | 6 |
| GO:0007406 | negative regulation of neuroblast proliferation | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 6 |
| GO:0007265 | Ras protein signal transduction | 1.82e-02 | 1.00e+00 | 3.274 | 2 | 3 | 75 |
| GO:0003924 | GTPase activity | 1.83e-02 | 1.00e+00 | 2.422 | 3 | 9 | 203 |
| GO:0005925 | focal adhesion | 1.86e-02 | 1.00e+00 | 1.971 | 4 | 18 | 370 |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 2 | 7 |
| GO:0000028 | ribosomal small subunit assembly | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
| GO:0002161 | aminoacyl-tRNA editing activity | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 2 | 7 |
| GO:0001939 | female pronucleus | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
| GO:0008584 | male gonad development | 1.91e-02 | 1.00e+00 | 3.236 | 2 | 2 | 77 |
| GO:0033180 | proton-transporting V-type ATPase, V1 domain | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 2 | 7 |
| GO:0030132 | clathrin coat of coated pit | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
| GO:0031497 | chromatin assembly | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
| GO:0000930 | gamma-tubulin complex | 1.91e-02 | 1.00e+00 | 5.695 | 1 | 1 | 7 |
| GO:0071013 | catalytic step 2 spliceosome | 2.00e-02 | 1.00e+00 | 3.199 | 2 | 7 | 79 |
| GO:0000733 | DNA strand renaturation | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
| GO:0006554 | lysine catabolic process | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 2 | 8 |
| GO:0045116 | protein neddylation | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 2 | 8 |
| GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 2 | 8 |
| GO:0070688 | MLL5-L complex | 2.19e-02 | 1.00e+00 | 5.503 | 1 | 1 | 8 |
| GO:0005681 | spliceosomal complex | 2.20e-02 | 1.00e+00 | 3.128 | 2 | 3 | 83 |
| GO:0006184 | GTP catabolic process | 2.26e-02 | 1.00e+00 | 2.306 | 3 | 9 | 220 |
| GO:0047485 | protein N-terminus binding | 2.35e-02 | 1.00e+00 | 3.076 | 2 | 4 | 86 |
| GO:0003016 | respiratory system process | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0006983 | ER overload response | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 2 | 9 |
| GO:0031065 | positive regulation of histone deacetylation | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0000075 | cell cycle checkpoint | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 2 | 9 |
| GO:0008494 | translation activator activity | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0032609 | interferon-gamma production | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 9 |
| GO:0007067 | mitotic nuclear division | 2.57e-02 | 1.00e+00 | 2.236 | 3 | 13 | 231 |
| GO:0016605 | PML body | 2.66e-02 | 1.00e+00 | 2.979 | 2 | 5 | 92 |
| GO:0042470 | melanosome | 2.66e-02 | 1.00e+00 | 2.979 | 2 | 10 | 92 |
| GO:0005200 | structural constituent of cytoskeleton | 2.71e-02 | 1.00e+00 | 2.963 | 2 | 7 | 93 |
| GO:0002199 | zona pellucida receptor complex | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0043032 | positive regulation of macrophage activation | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0090399 | replicative senescence | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0008195 | phosphatidate phosphatase activity | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0006069 | ethanol oxidation | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0046902 | regulation of mitochondrial membrane permeability | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0051604 | protein maturation | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0006450 | regulation of translational fidelity | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 2 | 10 |
| GO:0051775 | response to redox state | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0021756 | striatum development | 2.72e-02 | 1.00e+00 | 5.181 | 1 | 1 | 10 |
| GO:0021846 | cell proliferation in forebrain | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0032727 | positive regulation of interferon-alpha production | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0045120 | pronucleus | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0006098 | pentose-phosphate shunt | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 3 | 11 |
| GO:0008340 | determination of adult lifespan | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0010569 | regulation of double-strand break repair via homologous recombination | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0071850 | mitotic cell cycle arrest | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0071456 | cellular response to hypoxia | 2.99e-02 | 1.00e+00 | 2.888 | 2 | 4 | 98 |
| GO:0033762 | response to glucagon | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 1 | 11 |
| GO:0051290 | protein heterotetramerization | 2.99e-02 | 1.00e+00 | 5.043 | 1 | 2 | 11 |
| GO:0070935 | 3'-UTR-mediated mRNA stabilization | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 2 | 12 |
| GO:0021794 | thalamus development | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
| GO:0070266 | necroptotic process | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
| GO:0032461 | positive regulation of protein oligomerization | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
| GO:0009303 | rRNA transcription | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 12 |
| GO:0001530 | lipopolysaccharide binding | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 2 | 13 |
| GO:0042273 | ribosomal large subunit biogenesis | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 4 | 13 |
| GO:0006646 | phosphatidylethanolamine biosynthetic process | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 2 | 13 |
| GO:0005662 | DNA replication factor A complex | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 3 | 13 |
| GO:0008266 | poly(U) RNA binding | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
| GO:0051131 | chaperone-mediated protein complex assembly | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 1 | 13 |
| GO:0005504 | fatty acid binding | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0030330 | DNA damage response, signal transduction by p53 class mediator | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 2 | 14 |
| GO:2000378 | negative regulation of reactive oxygen species metabolic process | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0007020 | microtubule nucleation | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0007095 | mitotic G2 DNA damage checkpoint | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0009651 | response to salt stress | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 2 | 14 |
| GO:0048568 | embryonic organ development | 3.79e-02 | 1.00e+00 | 4.695 | 1 | 1 | 14 |
| GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 3 | 15 |
| GO:0035066 | positive regulation of histone acetylation | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 15 |
| GO:0072562 | blood microparticle | 4.07e-02 | 1.00e+00 | 2.645 | 2 | 4 | 116 |
| GO:0005635 | nuclear envelope | 4.07e-02 | 1.00e+00 | 2.645 | 2 | 6 | 116 |
| GO:0044237 | cellular metabolic process | 4.19e-02 | 1.00e+00 | 2.620 | 2 | 3 | 118 |
| GO:0050998 | nitric-oxide synthase binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 16 |
| GO:0046034 | ATP metabolic process | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 16 |
| GO:0006103 | 2-oxoglutarate metabolic process | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 1 | 16 |
| GO:0019899 | enzyme binding | 4.48e-02 | 1.00e+00 | 1.918 | 3 | 11 | 288 |
| GO:0042149 | cellular response to glucose starvation | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
| GO:0003746 | translation elongation factor activity | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 3 | 17 |
| GO:0075733 | intracellular transport of virus | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 2 | 17 |
| GO:0010243 | response to organonitrogen compound | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 2 | 17 |
| GO:0045777 | positive regulation of blood pressure | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
| GO:0006309 | apoptotic DNA fragmentation | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
| GO:0050870 | positive regulation of T cell activation | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 1 | 17 |
| GO:0006260 | DNA replication | 4.65e-02 | 1.00e+00 | 2.537 | 2 | 12 | 125 |
| GO:0007219 | Notch signaling pathway | 4.65e-02 | 1.00e+00 | 2.537 | 2 | 4 | 125 |
| GO:0071392 | cellular response to estradiol stimulus | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 18 |
| GO:0031122 | cytoplasmic microtubule organization | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 2 | 18 |
| GO:0035861 | site of double-strand break | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 18 |
| GO:0004004 | ATP-dependent RNA helicase activity | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 2 | 18 |
| GO:0015949 | nucleobase-containing small molecule interconversion | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 2 | 18 |
| GO:0005657 | replication fork | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 3 | 18 |
| GO:0051721 | protein phosphatase 2A binding | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 18 |
| GO:0006259 | DNA metabolic process | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 3 | 19 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
| GO:0035035 | histone acetyltransferase binding | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
| GO:0071158 | positive regulation of cell cycle arrest | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
| GO:0032733 | positive regulation of interleukin-10 production | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
| GO:0010165 | response to X-ray | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 2 | 19 |
| GO:0048863 | stem cell differentiation | 5.11e-02 | 1.00e+00 | 4.255 | 1 | 1 | 19 |
| GO:0015078 | hydrogen ion transmembrane transporter activity | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 3 | 20 |
| GO:0005719 | nuclear euchromatin | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 2 | 20 |
| GO:0002931 | response to ischemia | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
| GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 1 | 20 |
| GO:0006298 | mismatch repair | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 6 | 20 |
| GO:0000086 | G2/M transition of mitotic cell cycle | 5.48e-02 | 1.00e+00 | 2.405 | 2 | 7 | 137 |
| GO:0007369 | gastrulation | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 1 | 21 |
| GO:0008156 | negative regulation of DNA replication | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 1 | 21 |
| GO:0000718 | nucleotide-excision repair, DNA damage removal | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 5 | 21 |
| GO:0005669 | transcription factor TFIID complex | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 1 | 22 |
| GO:0090200 | positive regulation of release of cytochrome c from mitochondria | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 1 | 22 |
| GO:0006297 | nucleotide-excision repair, DNA gap filling | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 5 | 22 |
| GO:0006656 | phosphatidylcholine biosynthetic process | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 3 | 22 |
| GO:0032201 | telomere maintenance via semi-conservative replication | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 7 | 22 |
| GO:0030863 | cortical cytoskeleton | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 1 | 22 |
| GO:0036464 | cytoplasmic ribonucleoprotein granule | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 4 | 22 |
| GO:0006270 | DNA replication initiation | 5.90e-02 | 1.00e+00 | 4.043 | 1 | 5 | 22 |
| GO:0061024 | membrane organization | 6.13e-02 | 1.00e+00 | 2.313 | 2 | 5 | 146 |
| GO:0005525 | GTP binding | 6.15e-02 | 1.00e+00 | 1.730 | 3 | 11 | 328 |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 2 | 23 |
| GO:0043236 | laminin binding | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
| GO:0006513 | protein monoubiquitination | 6.16e-02 | 1.00e+00 | 3.979 | 1 | 1 | 23 |
| GO:0006457 | protein folding | 6.35e-02 | 1.00e+00 | 2.283 | 2 | 8 | 149 |
| GO:0001836 | release of cytochrome c from mitochondria | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 2 | 24 |
| GO:0048147 | negative regulation of fibroblast proliferation | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 24 |
| GO:0000794 | condensed nuclear chromosome | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 2 | 24 |
| GO:0006206 | pyrimidine nucleobase metabolic process | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 2 | 24 |
| GO:2000379 | positive regulation of reactive oxygen species metabolic process | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 24 |
| GO:0042100 | B cell proliferation | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
| GO:0001816 | cytokine production | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
| GO:0008536 | Ran GTPase binding | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 2 | 25 |
| GO:0071479 | cellular response to ionizing radiation | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
| GO:0007569 | cell aging | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 2 | 25 |
| GO:0042113 | B cell activation | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 2 | 25 |
| GO:0032735 | positive regulation of interleukin-12 production | 6.67e-02 | 1.00e+00 | 3.859 | 1 | 1 | 25 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 2 | 26 |
| GO:1900740 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 3 | 26 |
| GO:0000722 | telomere maintenance via recombination | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 7 | 26 |
| GO:0030148 | sphingolipid biosynthetic process | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 1 | 26 |
| GO:0004003 | ATP-dependent DNA helicase activity | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 3 | 27 |
| GO:0034080 | CENP-A containing nucleosome assembly | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 2 | 27 |
| GO:0007339 | binding of sperm to zona pellucida | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 1 | 27 |
| GO:0015991 | ATP hydrolysis coupled proton transport | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 4 | 28 |
| GO:0043022 | ribosome binding | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 3 | 28 |
| GO:0019894 | kinesin binding | 7.45e-02 | 1.00e+00 | 3.695 | 1 | 1 | 28 |
| GO:0000398 | mRNA splicing, via spliceosome | 7.58e-02 | 1.00e+00 | 2.136 | 2 | 12 | 165 |
| GO:0019005 | SCF ubiquitin ligase complex | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
| GO:0003730 | mRNA 3'-UTR binding | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 2 | 29 |
| GO:0010332 | response to gamma radiation | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 2 | 29 |
| GO:0030669 | clathrin-coated endocytic vesicle membrane | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 1 | 29 |
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 7.82e-02 | 1.00e+00 | 2.110 | 2 | 5 | 168 |
| GO:0006606 | protein import into nucleus | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 30 |
| GO:0051262 | protein tetramerization | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 3 | 30 |
| GO:0042254 | ribosome biogenesis | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 30 |
| GO:0021549 | cerebellum development | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 1 | 30 |
| GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 2 | 30 |
| GO:0006271 | DNA strand elongation involved in DNA replication | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 9 | 31 |
| GO:0031623 | receptor internalization | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 1 | 31 |
| GO:0046677 | response to antibiotic | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 2 | 31 |
| GO:0016604 | nuclear body | 8.21e-02 | 1.00e+00 | 3.548 | 1 | 2 | 31 |
| GO:0050661 | NADP binding | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 1 | 32 |
| GO:0002250 | adaptive immune response | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 1 | 32 |
| GO:0015992 | proton transport | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 3 | 32 |
| GO:0051219 | phosphoprotein binding | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 3 | 32 |
| GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 1 | 33 |
| GO:0030971 | receptor tyrosine kinase binding | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 2 | 33 |
| GO:0033077 | T cell differentiation in thymus | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 2 | 33 |
| GO:0031072 | heat shock protein binding | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 2 | 33 |
| GO:0008180 | COP9 signalosome | 8.97e-02 | 1.00e+00 | 3.415 | 1 | 1 | 34 |
| GO:0001085 | RNA polymerase II transcription factor binding | 8.97e-02 | 1.00e+00 | 3.415 | 1 | 2 | 34 |
| GO:0051701 | interaction with host | 8.97e-02 | 1.00e+00 | 3.415 | 1 | 4 | 34 |
| GO:0042277 | peptide binding | 9.22e-02 | 1.00e+00 | 3.373 | 1 | 2 | 35 |
| GO:0032588 | trans-Golgi network membrane | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
| GO:0034332 | adherens junction organization | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
| GO:0051402 | neuron apoptotic process | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 2 | 36 |
| GO:0032755 | positive regulation of interleukin-6 production | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 2 | 36 |
| GO:0006446 | regulation of translational initiation | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
| GO:0001895 | retina homeostasis | 9.47e-02 | 1.00e+00 | 3.333 | 1 | 1 | 36 |
| GO:0051084 | 'de novo' posttranslational protein folding | 9.72e-02 | 1.00e+00 | 3.293 | 1 | 4 | 37 |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | 9.72e-02 | 1.00e+00 | 3.293 | 1 | 3 | 37 |
| GO:0001756 | somitogenesis | 9.97e-02 | 1.00e+00 | 3.255 | 1 | 1 | 38 |
| GO:0070527 | platelet aggregation | 9.97e-02 | 1.00e+00 | 3.255 | 1 | 2 | 38 |
| GO:0090382 | phagosome maturation | 9.97e-02 | 1.00e+00 | 3.255 | 1 | 5 | 38 |
| GO:0006096 | glycolytic process | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 4 | 39 |
| GO:0032729 | positive regulation of interferon-gamma production | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 2 | 39 |
| GO:0021766 | hippocampus development | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 4 | 39 |
| GO:0031490 | chromatin DNA binding | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 2 | 39 |
| GO:0001228 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 1.05e-01 | 1.00e+00 | 3.181 | 1 | 2 | 40 |
| GO:0000781 | chromosome, telomeric region | 1.05e-01 | 1.00e+00 | 3.181 | 1 | 2 | 40 |
| GO:0006418 | tRNA aminoacylation for protein translation | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 5 | 42 |
| GO:0005902 | microvillus | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 2 | 42 |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 1 | 42 |
| GO:0014070 | response to organic cyclic compound | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 3 | 43 |
| GO:0010212 | response to ionizing radiation | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 1 | 43 |
| GO:0001701 | in utero embryonic development | 1.14e-01 | 1.00e+00 | 1.788 | 2 | 6 | 210 |
| GO:0048146 | positive regulation of fibroblast proliferation | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 2 | 44 |
| GO:0034613 | cellular protein localization | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 1 | 44 |
| GO:0006892 | post-Golgi vesicle-mediated transport | 1.15e-01 | 1.00e+00 | 3.043 | 1 | 2 | 44 |
| GO:0015030 | Cajal body | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 2 | 45 |
| GO:0006631 | fatty acid metabolic process | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 1 | 45 |
| GO:0030136 | clathrin-coated vesicle | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 1 | 46 |
| GO:0044297 | cell body | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 2 | 46 |
| GO:0043525 | positive regulation of neuron apoptotic process | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 2 | 46 |
| GO:0006283 | transcription-coupled nucleotide-excision repair | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 8 | 46 |
| GO:0045727 | positive regulation of translation | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 4 | 46 |
| GO:0021762 | substantia nigra development | 1.19e-01 | 1.00e+00 | 2.979 | 1 | 1 | 46 |
| GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 1.22e-01 | 1.00e+00 | 2.948 | 1 | 5 | 47 |
| GO:0005507 | copper ion binding | 1.24e-01 | 1.00e+00 | 2.918 | 1 | 2 | 48 |
| GO:0006950 | response to stress | 1.24e-01 | 1.00e+00 | 2.918 | 1 | 3 | 48 |
| GO:0031100 | organ regeneration | 1.29e-01 | 1.00e+00 | 2.859 | 1 | 4 | 50 |
| GO:0001523 | retinoid metabolic process | 1.29e-01 | 1.00e+00 | 2.859 | 1 | 2 | 50 |
| GO:0001948 | glycoprotein binding | 1.29e-01 | 1.00e+00 | 2.859 | 1 | 3 | 50 |
| GO:0035690 | cellular response to drug | 1.29e-01 | 1.00e+00 | 2.859 | 1 | 2 | 50 |
| GO:0005905 | coated pit | 1.32e-01 | 1.00e+00 | 2.830 | 1 | 2 | 51 |
| GO:0019221 | cytokine-mediated signaling pathway | 1.32e-01 | 1.00e+00 | 1.657 | 2 | 3 | 230 |
| GO:0008380 | RNA splicing | 1.34e-01 | 1.00e+00 | 1.645 | 2 | 13 | 232 |
| GO:0060041 | retina development in camera-type eye | 1.36e-01 | 1.00e+00 | 2.775 | 1 | 3 | 53 |
| GO:0097193 | intrinsic apoptotic signaling pathway | 1.41e-01 | 1.00e+00 | 2.721 | 1 | 4 | 55 |
| GO:0000226 | microtubule cytoskeleton organization | 1.41e-01 | 1.00e+00 | 2.721 | 1 | 3 | 55 |
| GO:0000932 | cytoplasmic mRNA processing body | 1.43e-01 | 1.00e+00 | 2.695 | 1 | 3 | 56 |
| GO:0008104 | protein localization | 1.43e-01 | 1.00e+00 | 2.695 | 1 | 3 | 56 |
| GO:0006968 | cellular defense response | 1.43e-01 | 1.00e+00 | 2.695 | 1 | 1 | 56 |
| GO:0006879 | cellular iron ion homeostasis | 1.46e-01 | 1.00e+00 | 2.670 | 1 | 5 | 57 |
| GO:0000724 | double-strand break repair via homologous recombination | 1.46e-01 | 1.00e+00 | 2.670 | 1 | 6 | 57 |
| GO:0012505 | endomembrane system | 1.46e-01 | 1.00e+00 | 2.670 | 1 | 2 | 57 |
| GO:0007202 | activation of phospholipase C activity | 1.48e-01 | 1.00e+00 | 2.645 | 1 | 1 | 58 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 1.48e-01 | 1.00e+00 | 2.645 | 1 | 1 | 58 |
| GO:0045216 | cell-cell junction organization | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 2 | 59 |
| GO:0000723 | telomere maintenance | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 8 | 59 |
| GO:0005643 | nuclear pore | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 4 | 59 |
| GO:0005840 | ribosome | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 2 | 59 |
| GO:0031966 | mitochondrial membrane | 1.51e-01 | 1.00e+00 | 2.620 | 1 | 1 | 59 |
| GO:0042802 | identical protein binding | 1.53e-01 | 1.00e+00 | 1.148 | 3 | 18 | 491 |
| GO:0005739 | mitochondrion | 1.59e-01 | 1.00e+00 | 0.794 | 5 | 24 | 1046 |
| GO:0042995 | cell projection | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 6 | 63 |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 1.62e-01 | 1.00e+00 | 2.503 | 1 | 1 | 64 |
| GO:0030141 | secretory granule | 1.69e-01 | 1.00e+00 | 2.436 | 1 | 2 | 67 |
| GO:0006665 | sphingolipid metabolic process | 1.71e-01 | 1.00e+00 | 2.415 | 1 | 2 | 68 |
| GO:0006338 | chromatin remodeling | 1.71e-01 | 1.00e+00 | 2.415 | 1 | 4 | 68 |
| GO:0009055 | electron carrier activity | 1.71e-01 | 1.00e+00 | 2.415 | 1 | 1 | 68 |
| GO:0043065 | positive regulation of apoptotic process | 1.74e-01 | 1.00e+00 | 1.405 | 2 | 8 | 274 |
| GO:0035264 | multicellular organism growth | 1.76e-01 | 1.00e+00 | 2.373 | 1 | 1 | 70 |
| GO:0034329 | cell junction assembly | 1.78e-01 | 1.00e+00 | 2.353 | 1 | 1 | 71 |
| GO:0032355 | response to estradiol | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 5 | 73 |
| GO:0000785 | chromatin | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 5 | 73 |
| GO:0055086 | nucleobase-containing small molecule metabolic process | 1.83e-01 | 1.00e+00 | 2.313 | 1 | 5 | 73 |
| GO:0042826 | histone deacetylase binding | 1.85e-01 | 1.00e+00 | 2.293 | 1 | 1 | 74 |
| GO:0002020 | protease binding | 1.85e-01 | 1.00e+00 | 2.293 | 1 | 4 | 74 |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 1.87e-01 | 1.00e+00 | 2.274 | 1 | 1 | 75 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.90e-01 | 1.00e+00 | 2.255 | 1 | 3 | 76 |
| GO:0046474 | glycerophospholipid biosynthetic process | 1.90e-01 | 1.00e+00 | 2.255 | 1 | 3 | 76 |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.92e-01 | 1.00e+00 | 2.236 | 1 | 5 | 77 |
| GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 1.92e-01 | 1.00e+00 | 2.236 | 1 | 6 | 77 |
| GO:0006334 | nucleosome assembly | 1.96e-01 | 1.00e+00 | 2.199 | 1 | 4 | 79 |
| GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 1.99e-01 | 1.00e+00 | 2.181 | 1 | 2 | 80 |
| GO:0051301 | cell division | 2.01e-01 | 1.00e+00 | 2.163 | 1 | 6 | 81 |
| GO:0001726 | ruffle | 2.03e-01 | 1.00e+00 | 2.145 | 1 | 4 | 82 |
| GO:0006898 | receptor-mediated endocytosis | 2.12e-01 | 1.00e+00 | 2.076 | 1 | 2 | 86 |
| GO:0050852 | T cell receptor signaling pathway | 2.16e-01 | 1.00e+00 | 2.043 | 1 | 2 | 88 |
| GO:0050821 | protein stabilization | 2.23e-01 | 1.00e+00 | 1.995 | 1 | 2 | 91 |
| GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 2.25e-01 | 1.00e+00 | 1.979 | 1 | 4 | 92 |
| GO:0006928 | cellular component movement | 2.25e-01 | 1.00e+00 | 1.979 | 1 | 7 | 92 |
| GO:0016311 | dephosphorylation | 2.29e-01 | 1.00e+00 | 1.948 | 1 | 3 | 94 |
| GO:0043231 | intracellular membrane-bounded organelle | 2.33e-01 | 1.00e+00 | 1.128 | 2 | 8 | 332 |
| GO:0006364 | rRNA processing | 2.33e-01 | 1.00e+00 | 1.918 | 1 | 5 | 96 |
| GO:0005813 | centrosome | 2.40e-01 | 1.00e+00 | 1.097 | 2 | 12 | 339 |
| GO:0014069 | postsynaptic density | 2.54e-01 | 1.00e+00 | 1.775 | 1 | 1 | 106 |
| GO:0005815 | microtubule organizing center | 2.63e-01 | 1.00e+00 | 1.721 | 1 | 4 | 110 |
| GO:0006461 | protein complex assembly | 2.65e-01 | 1.00e+00 | 1.708 | 1 | 6 | 111 |
| GO:0015630 | microtubule cytoskeleton | 2.67e-01 | 1.00e+00 | 1.695 | 1 | 5 | 112 |
| GO:0030308 | negative regulation of cell growth | 2.69e-01 | 1.00e+00 | 1.682 | 1 | 6 | 113 |
| GO:0005819 | spindle | 2.71e-01 | 1.00e+00 | 1.670 | 1 | 7 | 114 |
| GO:0032496 | response to lipopolysaccharide | 2.87e-01 | 1.00e+00 | 1.572 | 1 | 4 | 122 |
| GO:0007568 | aging | 2.89e-01 | 1.00e+00 | 1.560 | 1 | 3 | 123 |
| GO:0007050 | cell cycle arrest | 2.95e-01 | 1.00e+00 | 1.525 | 1 | 7 | 126 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 2.97e-01 | 1.00e+00 | 1.514 | 1 | 5 | 127 |
| GO:0005506 | iron ion binding | 2.97e-01 | 1.00e+00 | 1.514 | 1 | 3 | 127 |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 3.03e-01 | 1.00e+00 | 1.480 | 1 | 3 | 130 |
| GO:0009615 | response to virus | 3.06e-01 | 1.00e+00 | 1.458 | 1 | 6 | 132 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 3.08e-01 | 1.00e+00 | 1.447 | 1 | 3 | 133 |
| GO:0031982 | vesicle | 3.10e-01 | 1.00e+00 | 1.436 | 1 | 10 | 134 |
| GO:0006644 | phospholipid metabolic process | 3.16e-01 | 1.00e+00 | 1.405 | 1 | 5 | 137 |
| GO:0016055 | Wnt signaling pathway | 3.24e-01 | 1.00e+00 | 1.363 | 1 | 6 | 141 |
| GO:0005911 | cell-cell junction | 3.25e-01 | 1.00e+00 | 1.353 | 1 | 3 | 142 |
| GO:0008286 | insulin receptor signaling pathway | 3.29e-01 | 1.00e+00 | 1.333 | 1 | 6 | 144 |
| GO:0010628 | positive regulation of gene expression | 3.39e-01 | 1.00e+00 | 1.283 | 1 | 4 | 149 |
| GO:0008270 | zinc ion binding | 3.39e-01 | 1.00e+00 | 0.443 | 4 | 12 | 1067 |
| GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 3.42e-01 | 1.00e+00 | 1.264 | 1 | 2 | 151 |
| GO:0005769 | early endosome | 3.55e-01 | 1.00e+00 | 1.199 | 1 | 2 | 158 |
| GO:0006974 | cellular response to DNA damage stimulus | 3.55e-01 | 1.00e+00 | 1.199 | 1 | 8 | 158 |
| GO:0046777 | protein autophosphorylation | 3.55e-01 | 1.00e+00 | 1.199 | 1 | 3 | 158 |
| GO:0005198 | structural molecule activity | 3.57e-01 | 1.00e+00 | 1.190 | 1 | 4 | 159 |
| GO:0007596 | blood coagulation | 3.67e-01 | 1.00e+00 | 0.645 | 2 | 14 | 464 |
| GO:0006397 | mRNA processing | 3.74e-01 | 1.00e+00 | 1.102 | 1 | 3 | 169 |
| GO:0038095 | Fc-epsilon receptor signaling pathway | 3.78e-01 | 1.00e+00 | 1.085 | 1 | 7 | 171 |
| GO:0044212 | transcription regulatory region DNA binding | 3.78e-01 | 1.00e+00 | 1.085 | 1 | 6 | 171 |
| GO:0030424 | axon | 3.80e-01 | 1.00e+00 | 1.076 | 1 | 3 | 172 |
| GO:0006886 | intracellular protein transport | 3.81e-01 | 1.00e+00 | 1.068 | 1 | 4 | 173 |
| GO:0000287 | magnesium ion binding | 3.83e-01 | 1.00e+00 | 1.060 | 1 | 5 | 174 |
| GO:0055114 | oxidation-reduction process | 3.84e-01 | 1.00e+00 | 0.593 | 2 | 11 | 481 |
| GO:0016607 | nuclear speck | 3.85e-01 | 1.00e+00 | 1.051 | 1 | 4 | 175 |
| GO:0031965 | nuclear membrane | 3.86e-01 | 1.00e+00 | 1.043 | 1 | 4 | 176 |
| GO:0045893 | positive regulation of transcription, DNA-templated | 3.90e-01 | 1.00e+00 | 0.575 | 2 | 17 | 487 |
| GO:0019904 | protein domain specific binding | 3.95e-01 | 1.00e+00 | 1.003 | 1 | 6 | 181 |
| GO:0032403 | protein complex binding | 4.02e-01 | 1.00e+00 | 0.971 | 1 | 7 | 185 |
| GO:0005765 | lysosomal membrane | 4.54e-01 | 1.00e+00 | 0.734 | 1 | 5 | 218 |
| GO:0005622 | intracellular | 4.67e-01 | 1.00e+00 | 0.682 | 1 | 5 | 226 |
| GO:0008134 | transcription factor binding | 4.96e-01 | 1.00e+00 | 0.560 | 1 | 8 | 246 |
| GO:0043025 | neuronal cell body | 5.07e-01 | 1.00e+00 | 0.514 | 1 | 4 | 254 |
| GO:0004842 | ubiquitin-protein transferase activity | 5.10e-01 | 1.00e+00 | 0.503 | 1 | 4 | 256 |
| GO:0045087 | innate immune response | 5.11e-01 | 1.00e+00 | 0.236 | 2 | 20 | 616 |
| GO:0000166 | nucleotide binding | 5.31e-01 | 1.00e+00 | 0.415 | 1 | 6 | 272 |
| GO:0005975 | carbohydrate metabolic process | 5.34e-01 | 1.00e+00 | 0.405 | 1 | 5 | 274 |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | 5.35e-01 | 1.00e+00 | 0.399 | 1 | 6 | 275 |
| GO:0007283 | spermatogenesis | 5.36e-01 | 1.00e+00 | 0.394 | 1 | 6 | 276 |
| GO:0016567 | protein ubiquitination | 5.65e-01 | 1.00e+00 | 0.279 | 1 | 5 | 299 |
| GO:0005743 | mitochondrial inner membrane | 5.67e-01 | 1.00e+00 | 0.274 | 1 | 5 | 300 |
| GO:0005856 | cytoskeleton | 5.80e-01 | 1.00e+00 | 0.222 | 1 | 8 | 311 |
| GO:0004674 | protein serine/threonine kinase activity | 5.81e-01 | 1.00e+00 | 0.217 | 1 | 6 | 312 |
| GO:0035556 | intracellular signal transduction | 5.87e-01 | 1.00e+00 | 0.194 | 1 | 6 | 317 |
| GO:0030154 | cell differentiation | 5.96e-01 | 1.00e+00 | 0.158 | 1 | 5 | 325 |
| GO:0007411 | axon guidance | 5.98e-01 | 1.00e+00 | 0.149 | 1 | 9 | 327 |
| GO:0008283 | cell proliferation | 6.03e-01 | 1.00e+00 | 0.132 | 1 | 12 | 331 |
| GO:0003682 | chromatin binding | 6.06e-01 | 1.00e+00 | 0.119 | 1 | 12 | 334 |
| GO:0007275 | multicellular organismal development | 6.17e-01 | 1.00e+00 | 0.076 | 1 | 5 | 344 |
| GO:0008285 | negative regulation of cell proliferation | 6.41e-01 | 1.00e+00 | -0.017 | 1 | 11 | 367 |
| GO:0007155 | cell adhesion | 6.58e-01 | 1.00e+00 | -0.082 | 1 | 8 | 384 |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 6.62e-01 | 1.00e+00 | -0.161 | 2 | 19 | 811 |
| GO:0046982 | protein heterodimerization activity | 6.72e-01 | 1.00e+00 | -0.138 | 1 | 11 | 399 |
| GO:0006508 | proteolysis | 6.82e-01 | 1.00e+00 | -0.177 | 1 | 9 | 410 |
| GO:0009986 | cell surface | 6.93e-01 | 1.00e+00 | -0.219 | 1 | 9 | 422 |
| GO:0045892 | negative regulation of transcription, DNA-templated | 6.95e-01 | 1.00e+00 | -0.225 | 1 | 14 | 424 |
| GO:0006468 | protein phosphorylation | 7.30e-01 | 1.00e+00 | -0.365 | 1 | 10 | 467 |
| GO:0007165 | signal transduction | 7.46e-01 | 1.00e+00 | -0.389 | 2 | 17 | 950 |
| GO:0055085 | transmembrane transport | 7.64e-01 | 1.00e+00 | -0.503 | 1 | 8 | 514 |
| GO:0005615 | extracellular space | 7.76e-01 | 1.00e+00 | -0.478 | 2 | 17 | 1010 |
| GO:0046872 | metal ion binding | 7.82e-01 | 1.00e+00 | -0.429 | 3 | 24 | 1465 |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 8.09e-01 | 1.00e+00 | -0.700 | 1 | 12 | 589 |
| GO:0005783 | endoplasmic reticulum | 8.20e-01 | 1.00e+00 | -0.750 | 1 | 9 | 610 |
| GO:0042803 | protein homodimerization activity | 8.24e-01 | 1.00e+00 | -0.767 | 1 | 11 | 617 |
| GO:0005789 | endoplasmic reticulum membrane | 8.33e-01 | 1.00e+00 | -0.810 | 1 | 10 | 636 |
| GO:0005794 | Golgi apparatus | 8.40e-01 | 1.00e+00 | -0.842 | 1 | 14 | 650 |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | 8.79e-01 | 1.00e+00 | -1.044 | 1 | 11 | 748 |
| GO:0006351 | transcription, DNA-templated | 9.41e-01 | 1.00e+00 | -1.128 | 2 | 25 | 1585 |
| GO:0006355 | regulation of transcription, DNA-templated | 9.57e-01 | 1.00e+00 | -1.606 | 1 | 17 | 1104 |
| GO:0005886 | plasma membrane | 9.65e-01 | 1.00e+00 | -0.966 | 4 | 38 | 2834 |
| GO:0003677 | DNA binding | 9.80e-01 | 1.00e+00 | -1.897 | 1 | 26 | 1351 |
| GO:0016021 | integral component of membrane | 9.99e-01 | 1.00e+00 | -2.775 | 1 | 15 | 2483 |