meta-int-snw-1457

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-324	wolf-screen-ratio-mammosphere-adherent	0.819	1.30e-06	3.47e-03	6.48e-03	6	4
int-snw-1457	wolf-screen-ratio-mammosphere-adherent	0.950	4.10e-16	1.76e-03	3.13e-02	6	5

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-1457 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
EIF2S2	8894	39	1.075	0.940	103	Yes	-
PAFAH1B1	5048	17	0.691	0.819	126	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
TP53	7157	23	0.432	0.833	665	-	-
RPL6	6128	37	0.844	1.113	164	Yes	-
RPL14	9045	49	1.250	1.113	166	Yes	-
CSNK2A1	1457	2	0.030	0.950	311	-	-
APC	324	2	0.261	0.819	31	-	-
NCOA2	10499	2	0.469	0.819	95	Yes	-

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
APC	324	RPL14	9045	pd	>	reg.ITFP.txt: no annot
TP53	7157	EIF2S2	8894	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BioGrid, MINT, StelzlHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
APC	324	NCOA2	10499	pd	<>	reg.ITFP.txt: no annot
CSNK2A1	1457	EIF2S2	8894	pp	--	int.Intact: MI:0217(phosphorylation reaction); int.I2D: BIND, BCI, HPRD; int.HPRD: in vitro
PAFAH1B1	5048	RPL14	9045	pd	>	reg.ITFP.txt: no annot
CSNK2A1	1457	PAFAH1B1	5048	pp	--	int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro
CSNK2A1	1457	TP53	7157	pp	--	int.Intact: MI:0217(phosphorylation reaction); int.I2D: BCI, HPRD; int.HPRD: in vitro, in vivo
HNRNPC	3183	TP53	7157	pd	<	reg.ITFP.txt: no annot
APC	324	TP53	7157	pd	<	reg.TRANSFAC.txt: no annot
CSNK2A1	1457	HNRNPC	3183	pp	--	int.I2D: BCI; int.HPRD: in vitro, in vivo
APC	324	PAFAH1B1	5048	pd	<>	reg.ITFP.txt: no annot
CSNK2A1	1457	RPL6	6128	pp	--	int.Intact: MI:0217(phosphorylation reaction)
PAFAH1B1	5048	NCOA2	10499	pd	<>	reg.ITFP.txt: no annot
TP53	7157	NCOA2	10499	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
APC	324	CSNK2A1	1457	pp	--	int.I2D: BioGrid
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (326)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005829	cytosol	2.83e-06	4.62e-02	2.501	8	125	2562
GO:0003723	RNA binding	2.54e-05	4.15e-01	4.353	4	19	355
GO:0006413	translational initiation	4.10e-05	6.69e-01	5.376	3	12	131
GO:0033077	T cell differentiation in thymus	1.41e-04	1.00e+00	6.780	2	2	33
GO:0006412	translation	2.32e-04	1.00e+00	4.533	3	15	235
GO:0010467	gene expression	2.99e-04	1.00e+00	3.439	4	58	669
GO:0022625	cytosolic large ribosomal subunit	3.14e-04	1.00e+00	6.210	2	5	49
GO:0045732	positive regulation of protein catabolic process	3.40e-04	1.00e+00	6.152	2	4	51
GO:0000776	kinetochore	5.19e-04	1.00e+00	5.847	2	4	63
GO:0000235	astral microtubule	5.51e-04	1.00e+00	10.825	1	1	1
GO:0042483	negative regulation of odontogenesis	5.51e-04	1.00e+00	10.825	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	5.51e-04	1.00e+00	10.825	1	1	1
GO:0051660	establishment of centrosome localization	5.51e-04	1.00e+00	10.825	1	1	1
GO:0046469	platelet activating factor metabolic process	5.51e-04	1.00e+00	10.825	1	1	1
GO:0019083	viral transcription	8.56e-04	1.00e+00	5.485	2	8	81
GO:0047485	protein N-terminus binding	9.65e-04	1.00e+00	5.398	2	4	86
GO:0006415	translational termination	9.87e-04	1.00e+00	5.382	2	8	87
GO:0097252	oligodendrocyte apoptotic process	1.10e-03	1.00e+00	9.825	1	1	2
GO:0051081	nuclear envelope disassembly	1.10e-03	1.00e+00	9.825	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	1.10e-03	1.00e+00	9.825	1	2	2
GO:1901525	negative regulation of macromitophagy	1.10e-03	1.00e+00	9.825	1	1	2
GO:0002176	male germ cell proliferation	1.10e-03	1.00e+00	9.825	1	1	2
GO:0036035	osteoclast development	1.10e-03	1.00e+00	9.825	1	2	2
GO:0090343	positive regulation of cell aging	1.10e-03	1.00e+00	9.825	1	1	2
GO:0009798	axis specification	1.10e-03	1.00e+00	9.825	1	1	2
GO:0006414	translational elongation	1.13e-03	1.00e+00	5.285	2	11	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.41e-03	1.00e+00	5.124	2	8	104
GO:0006461	protein complex assembly	1.60e-03	1.00e+00	5.030	2	6	111
GO:0035794	positive regulation of mitochondrial membrane permeability	1.65e-03	1.00e+00	9.240	1	1	3
GO:0051097	negative regulation of helicase activity	1.65e-03	1.00e+00	9.240	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	1.65e-03	1.00e+00	9.240	1	1	3
GO:0035033	histone deacetylase regulator activity	1.65e-03	1.00e+00	9.240	1	1	3
GO:0002360	T cell lineage commitment	1.65e-03	1.00e+00	9.240	1	1	3
GO:0034103	regulation of tissue remodeling	1.65e-03	1.00e+00	9.240	1	1	3
GO:0021540	corpus callosum morphogenesis	1.65e-03	1.00e+00	9.240	1	1	3
GO:0045505	dynein intermediate chain binding	1.65e-03	1.00e+00	9.240	1	1	3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.69e-03	1.00e+00	4.992	2	10	114
GO:0019058	viral life cycle	1.72e-03	1.00e+00	4.979	2	10	115
GO:0044822	poly(A) RNA binding	1.82e-03	1.00e+00	2.750	4	50	1078
GO:0006355	regulation of transcription, DNA-templated	1.99e-03	1.00e+00	2.716	4	17	1104
GO:0044267	cellular protein metabolic process	2.03e-03	1.00e+00	3.458	3	24	495
GO:0007050	cell cycle arrest	2.05e-03	1.00e+00	4.847	2	7	126
GO:0071174	mitotic spindle checkpoint	2.20e-03	1.00e+00	8.825	1	1	4
GO:0090403	oxidative stress-induced premature senescence	2.20e-03	1.00e+00	8.825	1	1	4
GO:0030375	thyroid hormone receptor coactivator activity	2.20e-03	1.00e+00	8.825	1	1	4
GO:0002326	B cell lineage commitment	2.20e-03	1.00e+00	8.825	1	1	4
GO:0019887	protein kinase regulator activity	2.20e-03	1.00e+00	8.825	1	2	4
GO:0000790	nuclear chromatin	2.29e-03	1.00e+00	4.769	2	7	133
GO:0005515	protein binding	2.36e-03	1.00e+00	1.244	8	172	6127
GO:0003735	structural constituent of ribosome	2.56e-03	1.00e+00	4.685	2	8	141
GO:0016032	viral process	2.61e-03	1.00e+00	3.333	3	55	540
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	2.75e-03	1.00e+00	8.503	1	1	5
GO:0031023	microtubule organizing center organization	2.75e-03	1.00e+00	8.503	1	1	5
GO:0097371	MDM2/MDM4 family protein binding	2.75e-03	1.00e+00	8.503	1	1	5
GO:0008017	microtubule binding	2.90e-03	1.00e+00	4.596	2	7	150
GO:0006974	cellular response to DNA damage stimulus	3.21e-03	1.00e+00	4.521	2	8	158
GO:0030858	positive regulation of epithelial cell differentiation	3.30e-03	1.00e+00	8.240	1	1	6
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	3.30e-03	1.00e+00	8.240	1	1	6
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	3.30e-03	1.00e+00	8.240	1	1	6
GO:0002309	T cell proliferation involved in immune response	3.30e-03	1.00e+00	8.240	1	1	6
GO:0001667	ameboidal-type cell migration	3.30e-03	1.00e+00	8.240	1	1	6
GO:0008090	retrograde axon cargo transport	3.30e-03	1.00e+00	8.240	1	1	6
GO:0034452	dynactin binding	3.30e-03	1.00e+00	8.240	1	1	6
GO:0070245	positive regulation of thymocyte apoptotic process	3.30e-03	1.00e+00	8.240	1	1	6
GO:0007406	negative regulation of neuroblast proliferation	3.30e-03	1.00e+00	8.240	1	1	6
GO:0007097	nuclear migration	3.85e-03	1.00e+00	8.017	1	1	7
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	3.85e-03	1.00e+00	8.017	1	1	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	3.85e-03	1.00e+00	8.017	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3.85e-03	1.00e+00	8.017	1	1	7
GO:0001961	positive regulation of cytokine-mediated signaling pathway	3.85e-03	1.00e+00	8.017	1	1	7
GO:0017145	stem cell division	3.85e-03	1.00e+00	8.017	1	1	7
GO:0031497	chromatin assembly	3.85e-03	1.00e+00	8.017	1	1	7
GO:0045670	regulation of osteoclast differentiation	4.40e-03	1.00e+00	7.825	1	1	8
GO:0000733	DNA strand renaturation	4.40e-03	1.00e+00	7.825	1	1	8
GO:0031512	motile primary cilium	4.40e-03	1.00e+00	7.825	1	1	8
GO:0006983	ER overload response	4.95e-03	1.00e+00	7.655	1	2	9
GO:0031065	positive regulation of histone deacetylation	4.95e-03	1.00e+00	7.655	1	1	9
GO:0032319	regulation of Rho GTPase activity	4.95e-03	1.00e+00	7.655	1	2	9
GO:0021895	cerebral cortex neuron differentiation	4.95e-03	1.00e+00	7.655	1	1	9
GO:0045667	regulation of osteoblast differentiation	5.50e-03	1.00e+00	7.503	1	1	10
GO:0031274	positive regulation of pseudopodium assembly	5.50e-03	1.00e+00	7.503	1	1	10
GO:0090399	replicative senescence	5.50e-03	1.00e+00	7.503	1	1	10
GO:0001675	acrosome assembly	5.50e-03	1.00e+00	7.503	1	1	10
GO:0030877	beta-catenin destruction complex	5.50e-03	1.00e+00	7.503	1	2	10
GO:0046902	regulation of mitochondrial membrane permeability	5.50e-03	1.00e+00	7.503	1	1	10
GO:0001701	in utero embryonic development	5.59e-03	1.00e+00	4.110	2	6	210
GO:0045502	dynein binding	6.05e-03	1.00e+00	7.365	1	2	11
GO:0051010	microtubule plus-end binding	6.05e-03	1.00e+00	7.365	1	1	11
GO:0008340	determination of adult lifespan	6.05e-03	1.00e+00	7.365	1	1	11
GO:0071850	mitotic cell cycle arrest	6.05e-03	1.00e+00	7.365	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	6.05e-03	1.00e+00	7.365	1	3	11
GO:0045120	pronucleus	6.05e-03	1.00e+00	7.365	1	1	11
GO:2000273	positive regulation of receptor activity	6.05e-03	1.00e+00	7.365	1	1	11
GO:0031116	positive regulation of microtubule polymerization	6.05e-03	1.00e+00	7.365	1	2	11
GO:0021819	layer formation in cerebral cortex	6.05e-03	1.00e+00	7.365	1	1	11
GO:0016071	mRNA metabolic process	6.28e-03	1.00e+00	4.024	2	34	223
GO:0032886	regulation of microtubule-based process	6.60e-03	1.00e+00	7.240	1	4	12
GO:0070935	3'-UTR-mediated mRNA stabilization	6.60e-03	1.00e+00	7.240	1	2	12
GO:0016580	Sin3 complex	6.60e-03	1.00e+00	7.240	1	1	12
GO:0047496	vesicle transport along microtubule	6.60e-03	1.00e+00	7.240	1	1	12
GO:0045295	gamma-catenin binding	6.60e-03	1.00e+00	7.240	1	1	12
GO:0070266	necroptotic process	6.60e-03	1.00e+00	7.240	1	1	12
GO:0032461	positive regulation of protein oligomerization	6.60e-03	1.00e+00	7.240	1	1	12
GO:0009303	rRNA transcription	6.60e-03	1.00e+00	7.240	1	1	12
GO:0042273	ribosomal large subunit biogenesis	7.15e-03	1.00e+00	7.124	1	4	13
GO:0044295	axonal growth cone	7.15e-03	1.00e+00	7.124	1	1	13
GO:0043409	negative regulation of MAPK cascade	7.15e-03	1.00e+00	7.124	1	1	13
GO:0008266	poly(U) RNA binding	7.15e-03	1.00e+00	7.124	1	1	13
GO:0008134	transcription factor binding	7.60e-03	1.00e+00	3.882	2	8	246
GO:0016070	RNA metabolic process	7.66e-03	1.00e+00	3.876	2	34	247
GO:0035371	microtubule plus-end	7.70e-03	1.00e+00	7.017	1	1	14
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	7.70e-03	1.00e+00	7.017	1	2	14
GO:2000378	negative regulation of reactive oxygen species metabolic process	7.70e-03	1.00e+00	7.017	1	1	14
GO:0030330	DNA damage response, signal transduction by p53 class mediator	7.70e-03	1.00e+00	7.017	1	1	14
GO:0009651	response to salt stress	7.70e-03	1.00e+00	7.017	1	2	14
GO:0048568	embryonic organ development	7.70e-03	1.00e+00	7.017	1	1	14
GO:0048854	brain morphogenesis	8.24e-03	1.00e+00	6.918	1	1	15
GO:0016581	NuRD complex	8.79e-03	1.00e+00	6.825	1	1	16
GO:0007405	neuroblast proliferation	8.79e-03	1.00e+00	6.825	1	1	16
GO:0007026	negative regulation of microtubule depolymerization	8.79e-03	1.00e+00	6.825	1	1	16
GO:0046716	muscle cell cellular homeostasis	8.79e-03	1.00e+00	6.825	1	2	16
GO:0019226	transmission of nerve impulse	8.79e-03	1.00e+00	6.825	1	1	16
GO:0051276	chromosome organization	8.79e-03	1.00e+00	6.825	1	4	16
GO:0000132	establishment of mitotic spindle orientation	8.79e-03	1.00e+00	6.825	1	1	16
GO:0010906	regulation of glucose metabolic process	9.34e-03	1.00e+00	6.737	1	1	17
GO:0042149	cellular response to glucose starvation	9.34e-03	1.00e+00	6.737	1	1	17
GO:0043274	phospholipase binding	9.34e-03	1.00e+00	6.737	1	1	17
GO:0051879	Hsp90 protein binding	9.34e-03	1.00e+00	6.737	1	1	17
GO:0043065	positive regulation of apoptotic process	9.35e-03	1.00e+00	3.726	2	8	274
GO:0016922	ligand-dependent nuclear receptor binding	9.88e-03	1.00e+00	6.655	1	1	18
GO:0031122	cytoplasmic microtubule organization	9.88e-03	1.00e+00	6.655	1	2	18
GO:0051721	protein phosphatase 2A binding	9.88e-03	1.00e+00	6.655	1	1	18
GO:0045773	positive regulation of axon extension	9.88e-03	1.00e+00	6.655	1	2	18
GO:0005657	replication fork	9.88e-03	1.00e+00	6.655	1	3	18
GO:0035035	histone acetyltransferase binding	1.04e-02	1.00e+00	6.577	1	1	19
GO:0071158	positive regulation of cell cycle arrest	1.04e-02	1.00e+00	6.577	1	1	19
GO:0010165	response to X-ray	1.04e-02	1.00e+00	6.577	1	2	19
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	1.04e-02	1.00e+00	6.577	1	1	19
GO:0035257	nuclear hormone receptor binding	1.04e-02	1.00e+00	6.577	1	1	19
GO:0002931	response to ischemia	1.10e-02	1.00e+00	6.503	1	1	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	1.10e-02	1.00e+00	6.503	1	1	20
GO:0043234	protein complex	1.11e-02	1.00e+00	3.596	2	17	300
GO:0009306	protein secretion	1.15e-02	1.00e+00	6.432	1	1	21
GO:0008156	negative regulation of DNA replication	1.15e-02	1.00e+00	6.432	1	1	21
GO:0007369	gastrulation	1.15e-02	1.00e+00	6.432	1	1	21
GO:0009954	proximal/distal pattern formation	1.15e-02	1.00e+00	6.432	1	1	21
GO:0000281	mitotic cytokinesis	1.15e-02	1.00e+00	6.432	1	2	21
GO:0005669	transcription factor TFIID complex	1.21e-02	1.00e+00	6.365	1	1	22
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1.21e-02	1.00e+00	6.365	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.365	1	4	22
GO:0019901	protein kinase binding	1.26e-02	1.00e+00	3.503	2	21	320
GO:0016573	histone acetylation	1.26e-02	1.00e+00	6.301	1	2	23
GO:0043044	ATP-dependent chromatin remodeling	1.26e-02	1.00e+00	6.301	1	4	23
GO:0008135	translation factor activity, nucleic acid binding	1.32e-02	1.00e+00	6.240	1	4	24
GO:0001836	release of cytochrome c from mitochondria	1.32e-02	1.00e+00	6.240	1	2	24
GO:0046329	negative regulation of JNK cascade	1.32e-02	1.00e+00	6.240	1	1	24
GO:0048147	negative regulation of fibroblast proliferation	1.32e-02	1.00e+00	6.240	1	1	24
GO:0000060	protein import into nucleus, translocation	1.32e-02	1.00e+00	6.240	1	4	24
GO:2000379	positive regulation of reactive oxygen species metabolic process	1.32e-02	1.00e+00	6.240	1	1	24
GO:0031519	PcG protein complex	1.37e-02	1.00e+00	6.181	1	4	25
GO:0007569	cell aging	1.37e-02	1.00e+00	6.181	1	2	25
GO:0003682	chromatin binding	1.37e-02	1.00e+00	3.441	2	12	334
GO:0045296	cadherin binding	1.37e-02	1.00e+00	6.181	1	2	25
GO:0071479	cellular response to ionizing radiation	1.37e-02	1.00e+00	6.181	1	1	25
GO:0005813	centrosome	1.41e-02	1.00e+00	3.419	2	12	339
GO:0045931	positive regulation of mitotic cell cycle	1.42e-02	1.00e+00	6.124	1	1	26
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	1.42e-02	1.00e+00	6.124	1	3	26
GO:0030177	positive regulation of Wnt signaling pathway	1.53e-02	1.00e+00	6.017	1	3	28
GO:0005875	microtubule associated complex	1.53e-02	1.00e+00	6.017	1	2	28
GO:0007017	microtubule-based process	1.53e-02	1.00e+00	6.017	1	3	28
GO:0031492	nucleosomal DNA binding	1.53e-02	1.00e+00	6.017	1	4	28
GO:0031252	cell leading edge	1.59e-02	1.00e+00	5.967	1	3	29
GO:0005913	cell-cell adherens junction	1.59e-02	1.00e+00	5.967	1	2	29
GO:0010332	response to gamma radiation	1.59e-02	1.00e+00	5.967	1	2	29
GO:0003730	mRNA 3'-UTR binding	1.59e-02	1.00e+00	5.967	1	2	29
GO:0010977	negative regulation of neuron projection development	1.64e-02	1.00e+00	5.918	1	2	30
GO:0051262	protein tetramerization	1.64e-02	1.00e+00	5.918	1	3	30
GO:0008285	negative regulation of cell proliferation	1.64e-02	1.00e+00	3.305	2	11	367
GO:0021549	cerebellum development	1.64e-02	1.00e+00	5.918	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	1.64e-02	1.00e+00	5.918	1	2	30
GO:0046677	response to antibiotic	1.70e-02	1.00e+00	5.870	1	2	31
GO:0016604	nuclear body	1.70e-02	1.00e+00	5.870	1	2	31
GO:0061077	chaperone-mediated protein folding	1.70e-02	1.00e+00	5.870	1	2	31
GO:0007094	mitotic spindle assembly checkpoint	1.70e-02	1.00e+00	5.870	1	5	31
GO:0009953	dorsal/ventral pattern formation	1.75e-02	1.00e+00	5.825	1	1	32
GO:0051219	phosphoprotein binding	1.75e-02	1.00e+00	5.825	1	3	32
GO:0034644	cellular response to UV	1.75e-02	1.00e+00	5.825	1	5	32
GO:0030971	receptor tyrosine kinase binding	1.81e-02	1.00e+00	5.780	1	2	33
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	1.81e-02	1.00e+00	5.780	1	1	33
GO:0070830	tight junction assembly	1.81e-02	1.00e+00	5.780	1	1	33
GO:0007611	learning or memory	1.86e-02	1.00e+00	5.737	1	2	34
GO:0005654	nucleoplasm	1.86e-02	1.00e+00	2.313	3	83	1095
GO:0001085	RNA polymerase II transcription factor binding	1.86e-02	1.00e+00	5.737	1	2	34
GO:0000278	mitotic cell cycle	1.91e-02	1.00e+00	3.188	2	52	398
GO:0001942	hair follicle development	1.91e-02	1.00e+00	5.695	1	2	35
GO:0051402	neuron apoptotic process	1.97e-02	1.00e+00	5.655	1	2	36
GO:0048538	thymus development	1.97e-02	1.00e+00	5.655	1	2	36
GO:0001756	somitogenesis	2.08e-02	1.00e+00	5.577	1	1	38
GO:0021766	hippocampus development	2.13e-02	1.00e+00	5.539	1	4	39
GO:0051781	positive regulation of cell division	2.13e-02	1.00e+00	5.539	1	1	39
GO:0006284	base-excision repair	2.13e-02	1.00e+00	5.539	1	7	39
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.18e-02	1.00e+00	5.503	1	2	40
GO:0035019	somatic stem cell maintenance	2.18e-02	1.00e+00	5.503	1	2	40
GO:0005881	cytoplasmic microtubule	2.24e-02	1.00e+00	5.467	1	2	41
GO:0045785	positive regulation of cell adhesion	2.24e-02	1.00e+00	5.467	1	5	41
GO:0050885	neuromuscular process controlling balance	2.24e-02	1.00e+00	5.467	1	1	41
GO:0021987	cerebral cortex development	2.29e-02	1.00e+00	5.432	1	3	42
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	2.35e-02	1.00e+00	5.398	1	3	43
GO:0004402	histone acetyltransferase activity	2.35e-02	1.00e+00	5.398	1	1	43
GO:0034613	cellular protein localization	2.40e-02	1.00e+00	5.365	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2.40e-02	1.00e+00	5.365	1	2	44
GO:0005871	kinesin complex	2.40e-02	1.00e+00	5.365	1	2	44
GO:0016328	lateral plasma membrane	2.51e-02	1.00e+00	5.301	1	2	46
GO:0043525	positive regulation of neuron apoptotic process	2.51e-02	1.00e+00	5.301	1	2	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	2.56e-02	1.00e+00	5.270	1	5	47
GO:0008344	adult locomotory behavior	2.56e-02	1.00e+00	5.270	1	1	47
GO:0048511	rhythmic process	2.56e-02	1.00e+00	5.270	1	2	47
GO:0005507	copper ion binding	2.62e-02	1.00e+00	5.240	1	2	48
GO:0003743	translation initiation factor activity	2.67e-02	1.00e+00	5.210	1	4	49
GO:0035690	cellular response to drug	2.72e-02	1.00e+00	5.181	1	2	50
GO:0003684	damaged DNA binding	2.78e-02	1.00e+00	5.152	1	11	51
GO:0042802	identical protein binding	2.83e-02	1.00e+00	2.885	2	18	491
GO:0016042	lipid catabolic process	2.83e-02	1.00e+00	5.124	1	1	52
GO:0060041	retina development in camera-type eye	2.89e-02	1.00e+00	5.097	1	3	53
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.94e-02	1.00e+00	5.070	1	5	54
GO:0000226	microtubule cytoskeleton organization	2.99e-02	1.00e+00	5.043	1	3	55
GO:0097193	intrinsic apoptotic signaling pathway	2.99e-02	1.00e+00	5.043	1	4	55
GO:0002039	p53 binding	2.99e-02	1.00e+00	5.043	1	7	55
GO:0008104	protein localization	3.05e-02	1.00e+00	5.017	1	3	56
GO:0051087	chaperone binding	3.21e-02	1.00e+00	4.942	1	6	59
GO:0008013	beta-catenin binding	3.26e-02	1.00e+00	4.918	1	4	60
GO:0006302	double-strand break repair	3.37e-02	1.00e+00	4.870	1	8	62
GO:0019903	protein phosphatase binding	3.42e-02	1.00e+00	4.847	1	4	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	3.42e-02	1.00e+00	4.847	1	1	63
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	3.48e-02	1.00e+00	4.825	1	1	64
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.53e-02	1.00e+00	4.802	1	22	65
GO:0007409	axonogenesis	3.58e-02	1.00e+00	4.780	1	1	66
GO:0006289	nucleotide-excision repair	3.74e-02	1.00e+00	4.716	1	12	69
GO:0006915	apoptotic process	3.74e-02	1.00e+00	2.667	2	34	571
GO:0030307	positive regulation of cell growth	3.80e-02	1.00e+00	4.695	1	2	70
GO:0035264	multicellular organism growth	3.80e-02	1.00e+00	4.695	1	1	70
GO:0032587	ruffle membrane	3.90e-02	1.00e+00	4.655	1	4	72
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.96e-02	1.00e+00	2.622	2	12	589
GO:0000785	chromatin	3.96e-02	1.00e+00	4.635	1	5	73
GO:0002020	protease binding	4.01e-02	1.00e+00	4.615	1	4	74
GO:0060070	canonical Wnt signaling pathway	4.06e-02	1.00e+00	4.596	1	3	75
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	4.06e-02	1.00e+00	4.596	1	1	75
GO:0007265	Ras protein signal transduction	4.06e-02	1.00e+00	4.596	1	3	75
GO:0008584	male gonad development	4.17e-02	1.00e+00	4.558	1	2	77
GO:0001822	kidney development	4.27e-02	1.00e+00	4.521	1	3	79
GO:0071013	catalytic step 2 spliceosome	4.27e-02	1.00e+00	4.521	1	7	79
GO:0005681	spliceosomal complex	4.49e-02	1.00e+00	4.449	1	3	83
GO:0009952	anterior/posterior pattern specification	4.54e-02	1.00e+00	4.432	1	2	84
GO:0090090	negative regulation of canonical Wnt signaling pathway	4.75e-02	1.00e+00	4.365	1	3	88
GO:0016363	nuclear matrix	4.96e-02	1.00e+00	4.301	1	11	92
GO:0005923	tight junction	4.96e-02	1.00e+00	4.301	1	2	92
GO:0016605	PML body	4.96e-02	1.00e+00	4.301	1	5	92
GO:0001649	osteoblast differentiation	5.12e-02	1.00e+00	4.255	1	6	95
GO:0001764	neuron migration	5.17e-02	1.00e+00	4.240	1	2	96
GO:0006364	rRNA processing	5.17e-02	1.00e+00	4.240	1	5	96
GO:0030426	growth cone	5.22e-02	1.00e+00	4.225	1	3	97
GO:0071456	cellular response to hypoxia	5.28e-02	1.00e+00	4.210	1	4	98
GO:0005938	cell cortex	5.85e-02	1.00e+00	4.056	1	3	109
GO:0030308	negative regulation of cell growth	6.06e-02	1.00e+00	4.004	1	6	113
GO:0005635	nuclear envelope	6.22e-02	1.00e+00	3.967	1	6	116
GO:0016020	membrane	6.27e-02	1.00e+00	1.640	3	80	1746
GO:0007219	Notch signaling pathway	6.69e-02	1.00e+00	3.859	1	4	125
GO:0008201	heparin binding	6.79e-02	1.00e+00	3.836	1	2	127
GO:0030036	actin cytoskeleton organization	6.89e-02	1.00e+00	3.813	1	5	129
GO:0030027	lamellipodium	6.95e-02	1.00e+00	3.802	1	4	130
GO:0007179	transforming growth factor beta receptor signaling pathway	6.95e-02	1.00e+00	3.802	1	3	130
GO:0030335	positive regulation of cell migration	6.95e-02	1.00e+00	3.802	1	6	130
GO:0046983	protein dimerization activity	7.00e-02	1.00e+00	3.791	1	3	131
GO:0016477	cell migration	7.00e-02	1.00e+00	3.791	1	6	131
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	7.04e-02	1.00e+00	2.161	2	19	811
GO:0000086	G2/M transition of mitotic cell cycle	7.31e-02	1.00e+00	3.726	1	7	137
GO:0044255	cellular lipid metabolic process	7.46e-02	1.00e+00	3.695	1	4	140
GO:0016055	Wnt signaling pathway	7.51e-02	1.00e+00	3.685	1	6	141
GO:0042981	regulation of apoptotic process	8.03e-02	1.00e+00	3.586	1	26	151
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	8.03e-02	1.00e+00	3.586	1	2	151
GO:0000398	mRNA splicing, via spliceosome	8.74e-02	1.00e+00	3.458	1	12	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.89e-02	1.00e+00	3.432	1	5	168
GO:0044212	transcription regulatory region DNA binding	9.05e-02	1.00e+00	3.407	1	6	171
GO:0030424	axon	9.10e-02	1.00e+00	3.398	1	3	172
GO:0007165	signal transduction	9.28e-02	1.00e+00	1.933	2	17	950
GO:0031965	nuclear membrane	9.30e-02	1.00e+00	3.365	1	4	176
GO:0005634	nucleus	9.37e-02	1.00e+00	0.909	5	131	4828
GO:0031625	ubiquitin protein ligase binding	9.50e-02	1.00e+00	3.333	1	13	180
GO:0004871	signal transducer activity	1.13e-01	1.00e+00	3.070	1	4	216
GO:0007067	mitotic nuclear division	1.20e-01	1.00e+00	2.973	1	13	231
GO:0005759	mitochondrial matrix	1.21e-01	1.00e+00	2.960	1	12	233
GO:0008380	RNA splicing	1.21e-01	1.00e+00	2.967	1	13	232
GO:0003713	transcription coactivator activity	1.24e-01	1.00e+00	2.924	1	10	239
GO:0043025	neuronal cell body	1.32e-01	1.00e+00	2.836	1	4	254
GO:0000166	nucleotide binding	1.40e-01	1.00e+00	2.737	1	6	272
GO:0019899	enzyme binding	1.48e-01	1.00e+00	2.655	1	11	288
GO:0070062	extracellular vesicular exosome	1.50e-01	1.00e+00	1.113	3	98	2516
GO:0005737	cytoplasm	1.54e-01	1.00e+00	0.867	4	98	3976
GO:0004674	protein serine/threonine kinase activity	1.59e-01	1.00e+00	2.539	1	6	312
GO:0030154	cell differentiation	1.66e-01	1.00e+00	2.480	1	5	325
GO:0003677	DNA binding	1.67e-01	1.00e+00	1.425	2	26	1351
GO:0007411	axon guidance	1.67e-01	1.00e+00	2.471	1	9	327
GO:0008283	cell proliferation	1.68e-01	1.00e+00	2.454	1	12	331
GO:0005524	ATP binding	1.68e-01	1.00e+00	1.422	2	46	1354
GO:0007275	multicellular organismal development	1.75e-01	1.00e+00	2.398	1	5	344
GO:0007268	synaptic transmission	1.79e-01	1.00e+00	2.361	1	2	353
GO:0005925	focal adhesion	1.87e-01	1.00e+00	2.293	1	18	370
GO:0007155	cell adhesion	1.93e-01	1.00e+00	2.240	1	8	384
GO:0008284	positive regulation of cell proliferation	1.97e-01	1.00e+00	2.210	1	8	392
GO:0046982	protein heterodimerization activity	2.00e-01	1.00e+00	2.184	1	11	399
GO:0045892	negative regulation of transcription, DNA-templated	2.11e-01	1.00e+00	2.097	1	14	424
GO:0006351	transcription, DNA-templated	2.15e-01	1.00e+00	1.194	2	25	1585
GO:0043066	negative regulation of apoptotic process	2.15e-01	1.00e+00	2.066	1	30	433
GO:0007596	blood coagulation	2.29e-01	1.00e+00	1.967	1	14	464
GO:0006468	protein phosphorylation	2.30e-01	1.00e+00	1.957	1	10	467
GO:0005730	nucleolus	2.36e-01	1.00e+00	1.107	2	70	1684
GO:0045893	positive regulation of transcription, DNA-templated	2.39e-01	1.00e+00	1.897	1	17	487
GO:0048471	perinuclear region of cytoplasm	2.54e-01	1.00e+00	1.794	1	12	523
GO:0005783	endoplasmic reticulum	2.90e-01	1.00e+00	1.572	1	9	610
GO:0042803	protein homodimerization activity	2.93e-01	1.00e+00	1.555	1	11	617
GO:0003700	sequence-specific DNA binding transcription factor activity	3.44e-01	1.00e+00	1.278	1	11	748
GO:0005739	mitochondrion	4.49e-01	1.00e+00	0.794	1	24	1046
GO:0008270	zinc ion binding	4.56e-01	1.00e+00	0.765	1	12	1067
GO:0005886	plasma membrane	4.81e-01	1.00e+00	0.356	2	38	2834
GO:0044281	small molecule metabolic process	5.25e-01	1.00e+00	0.486	1	57	1295
GO:0046872	metal ion binding	5.71e-01	1.00e+00	0.308	1	24	1465

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-1457

Interacting subnets

Genes (9)

Interactions (16)

Related GO terms (326)