int-snw-1457

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.950	4.10e-16	1.76e-03	3.13e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-1457 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ CSNK2A1 ]	1457	1	0.030	0.950	311	-	-
EIF2S2	8894	27	1.075	1.138	81	Yes	-
PAFAH1B1	5048	6	0.691	1.076	71	Yes	-
HNRNPC	3183	20	1.812	1.026	119	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
CSNK2A1	1457	PAFAH1B1	5048	pp	--	int.I2D: HPRD, BCI, BioGrid; int.HPRD: in vitro
CSNK2A1	1457	EIF2S2	8894	pp	--	int.Intact: MI:0217(phosphorylation reaction); int.I2D: BIND, BCI, HPRD; int.HPRD: in vitro
CSNK2A1	1457	RPL6	6128	pp	--	int.Intact: MI:0217(phosphorylation reaction)
CSNK2A1	1457	HNRNPC	3183	pp	--	int.I2D: BCI; int.HPRD: in vitro, in vivo

Related GO terms (137)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003723	RNA binding	4.49e-06	6.47e-02	4.813	4	20	342
GO:0006413	translational initiation	1.44e-05	2.07e-01	5.783	3	17	131
GO:0005829	cytosol	2.67e-05	3.86e-01	2.531	6	132	2496
GO:0010467	gene expression	6.39e-05	9.21e-01	3.845	4	59	669
GO:0006412	translation	7.73e-05	1.00e+00	4.971	3	20	230
GO:0022625	cytosolic large ribosomal subunit	1.68e-04	1.00e+00	6.616	2	6	49
GO:0044822	poly(A) RNA binding	3.80e-04	1.00e+00	3.187	4	49	1056
GO:0000235	astral microtubule	4.16e-04	1.00e+00	11.231	1	1	1
GO:0051660	establishment of centrosome localization	4.16e-04	1.00e+00	11.231	1	1	1
GO:0046469	platelet activating factor metabolic process	4.16e-04	1.00e+00	11.231	1	1	1
GO:0019083	viral transcription	4.61e-04	1.00e+00	5.891	2	10	81
GO:0006415	translational termination	5.31e-04	1.00e+00	5.788	2	10	87
GO:0006414	translational elongation	6.07e-04	1.00e+00	5.692	2	13	93
GO:0044267	cellular protein metabolic process	6.55e-04	1.00e+00	3.927	3	29	474
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.58e-04	1.00e+00	5.531	2	10	104
GO:0051081	nuclear envelope disassembly	8.32e-04	1.00e+00	10.231	1	2	2
GO:0002176	male germ cell proliferation	8.32e-04	1.00e+00	10.231	1	1	2
GO:0021540	corpus callosum morphogenesis	8.32e-04	1.00e+00	10.231	1	1	2
GO:0036035	osteoclast development	8.32e-04	1.00e+00	10.231	1	2	2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	9.10e-04	1.00e+00	5.398	2	11	114
GO:0019058	viral life cycle	9.26e-04	1.00e+00	5.386	2	13	115
GO:0005850	eukaryotic translation initiation factor 2 complex	1.25e-03	1.00e+00	9.646	1	1	3
GO:0045505	dynein intermediate chain binding	1.25e-03	1.00e+00	9.646	1	1	3
GO:0003735	structural constituent of ribosome	1.31e-03	1.00e+00	5.133	2	10	137
GO:0071174	mitotic spindle checkpoint	1.66e-03	1.00e+00	9.231	1	1	4
GO:0031023	microtubule organizing center organization	2.08e-03	1.00e+00	8.909	1	1	5
GO:0008090	retrograde axon cargo transport	2.49e-03	1.00e+00	8.646	1	2	6
GO:0007097	nuclear migration	2.49e-03	1.00e+00	8.646	1	1	6
GO:0034452	dynactin binding	2.49e-03	1.00e+00	8.646	1	1	6
GO:0001667	ameboidal-type cell migration	2.49e-03	1.00e+00	8.646	1	1	6
GO:0001961	positive regulation of cytokine-mediated signaling pathway	2.91e-03	1.00e+00	8.424	1	1	7
GO:0017145	stem cell division	2.91e-03	1.00e+00	8.424	1	1	7
GO:0031512	motile primary cilium	3.32e-03	1.00e+00	8.231	1	1	8
GO:0016071	mRNA metabolic process	3.43e-03	1.00e+00	4.430	2	31	223
GO:0032319	regulation of Rho GTPase activity	3.74e-03	1.00e+00	8.061	1	2	9
GO:0021895	cerebral cortex neuron differentiation	3.74e-03	1.00e+00	8.061	1	1	9
GO:0001675	acrosome assembly	4.15e-03	1.00e+00	7.909	1	1	10
GO:0016070	RNA metabolic process	4.19e-03	1.00e+00	4.283	2	32	247
GO:0045502	dynein binding	4.57e-03	1.00e+00	7.772	1	2	11
GO:0045120	pronucleus	4.57e-03	1.00e+00	7.772	1	2	11
GO:0021819	layer formation in cerebral cortex	4.57e-03	1.00e+00	7.772	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	4.98e-03	1.00e+00	7.646	1	2	12
GO:0016580	Sin3 complex	4.98e-03	1.00e+00	7.646	1	1	12
GO:0047496	vesicle transport along microtubule	4.98e-03	1.00e+00	7.646	1	2	12
GO:0042273	ribosomal large subunit biogenesis	5.40e-03	1.00e+00	7.531	1	4	13
GO:0008266	poly(U) RNA binding	5.40e-03	1.00e+00	7.531	1	1	13
GO:0019226	transmission of nerve impulse	5.81e-03	1.00e+00	7.424	1	1	14
GO:0048854	brain morphogenesis	6.22e-03	1.00e+00	7.324	1	1	15
GO:0016581	NuRD complex	6.64e-03	1.00e+00	7.231	1	1	16
GO:0007405	neuroblast proliferation	6.64e-03	1.00e+00	7.231	1	1	16
GO:0043274	phospholipase binding	6.64e-03	1.00e+00	7.231	1	1	16
GO:0000132	establishment of mitotic spindle orientation	6.64e-03	1.00e+00	7.231	1	1	16
GO:0051879	Hsp90 protein binding	7.05e-03	1.00e+00	7.144	1	1	17
GO:0045773	positive regulation of axon extension	7.47e-03	1.00e+00	7.061	1	4	18
GO:0009306	protein secretion	8.29e-03	1.00e+00	6.909	1	1	20
GO:0036464	cytoplasmic ribonucleoprotein granule	9.12e-03	1.00e+00	6.772	1	4	22
GO:0046329	negative regulation of JNK cascade	9.53e-03	1.00e+00	6.708	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	9.53e-03	1.00e+00	6.708	1	4	23
GO:0008135	translation factor activity, nucleic acid binding	9.94e-03	1.00e+00	6.646	1	7	24
GO:0000278	mitotic cell cycle	1.02e-02	1.00e+00	3.620	2	48	391
GO:0031519	PcG protein complex	1.04e-02	1.00e+00	6.587	1	4	25
GO:0045931	positive regulation of mitotic cell cycle	1.08e-02	1.00e+00	6.531	1	1	26
GO:0003730	mRNA 3'-UTR binding	1.08e-02	1.00e+00	6.531	1	2	26
GO:0007017	microtubule-based process	1.12e-02	1.00e+00	6.476	1	3	27
GO:0030177	positive regulation of Wnt signaling pathway	1.12e-02	1.00e+00	6.476	1	3	27
GO:0031492	nucleosomal DNA binding	1.12e-02	1.00e+00	6.476	1	4	27
GO:0031252	cell leading edge	1.16e-02	1.00e+00	6.424	1	4	28
GO:0010977	negative regulation of neuron projection development	1.16e-02	1.00e+00	6.424	1	2	28
GO:0005875	microtubule associated complex	1.16e-02	1.00e+00	6.424	1	2	28
GO:0061077	chaperone-mediated protein folding	1.28e-02	1.00e+00	6.277	1	2	31
GO:0051219	phosphoprotein binding	1.32e-02	1.00e+00	6.231	1	2	32
GO:0007611	learning or memory	1.41e-02	1.00e+00	6.144	1	2	34
GO:0021766	hippocampus development	1.57e-02	1.00e+00	5.983	1	4	38
GO:0050885	neuromuscular process controlling balance	1.65e-02	1.00e+00	5.909	1	1	40
GO:0021987	cerebral cortex development	1.73e-02	1.00e+00	5.839	1	3	42
GO:0008344	adult locomotory behavior	1.82e-02	1.00e+00	5.772	1	1	44
GO:0005871	kinesin complex	1.82e-02	1.00e+00	5.772	1	3	44
GO:0016032	viral process	1.86e-02	1.00e+00	3.170	2	55	534
GO:0048511	rhythmic process	1.86e-02	1.00e+00	5.739	1	3	45
GO:0016042	lipid catabolic process	1.98e-02	1.00e+00	5.646	1	2	48
GO:0003743	translation initiation factor activity	2.02e-02	1.00e+00	5.616	1	8	49
GO:0045732	positive regulation of protein catabolic process	2.06e-02	1.00e+00	5.587	1	3	50
GO:0000226	microtubule cytoskeleton organization	2.14e-02	1.00e+00	5.531	1	3	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.19e-02	1.00e+00	5.503	1	5	53
GO:0016020	membrane	2.41e-02	1.00e+00	2.101	3	90	1681
GO:0000776	kinetochore	2.59e-02	1.00e+00	5.254	1	4	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	2.59e-02	1.00e+00	5.254	1	1	63
GO:0030307	positive regulation of cell growth	2.84e-02	1.00e+00	5.123	1	3	69
GO:0008584	male gonad development	3.08e-02	1.00e+00	5.002	1	3	75
GO:0071013	catalytic step 2 spliceosome	3.20e-02	1.00e+00	4.946	1	4	78
GO:0005681	spliceosomal complex	3.40e-02	1.00e+00	4.856	1	4	83
GO:0047485	protein N-terminus binding	3.53e-02	1.00e+00	4.805	1	5	86
GO:0001649	osteoblast differentiation	3.77e-02	1.00e+00	4.708	1	6	92
GO:0001764	neuron migration	3.81e-02	1.00e+00	4.692	1	3	93
GO:0006364	rRNA processing	3.85e-02	1.00e+00	4.677	1	6	94
GO:0030426	growth cone	3.93e-02	1.00e+00	4.646	1	5	96
GO:0005938	cell cortex	4.25e-02	1.00e+00	4.531	1	3	104
GO:0005635	nuclear envelope	4.61e-02	1.00e+00	4.411	1	6	113
GO:0008201	heparin binding	4.97e-02	1.00e+00	4.300	1	4	122
GO:0005515	protein binding	4.97e-02	1.00e+00	0.997	5	184	6024
GO:0030036	actin cytoskeleton organization	5.01e-02	1.00e+00	4.289	1	5	123
GO:0000790	nuclear chromatin	5.25e-02	1.00e+00	4.220	1	9	129
GO:0000086	G2/M transition of mitotic cell cycle	5.53e-02	1.00e+00	4.144	1	9	136
GO:0016055	Wnt signaling pathway	5.61e-02	1.00e+00	4.123	1	7	138
GO:0006355	regulation of transcription, DNA-templated	5.94e-02	1.00e+00	2.270	2	18	997
GO:0008017	microtubule binding	5.96e-02	1.00e+00	4.031	1	6	147
GO:0070062	extracellular vesicular exosome	6.20e-02	1.00e+00	1.587	3	104	2400
GO:0000398	mRNA splicing, via spliceosome	6.63e-02	1.00e+00	3.874	1	8	164
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	6.67e-02	1.00e+00	3.865	1	7	165
GO:0030424	axon	6.71e-02	1.00e+00	3.856	1	4	166
GO:0031965	nuclear membrane	6.79e-02	1.00e+00	3.839	1	3	168
GO:0001701	in utero embryonic development	8.08e-02	1.00e+00	3.580	1	8	201
GO:0007067	mitotic nuclear division	9.08e-02	1.00e+00	3.405	1	14	227
GO:0008380	RNA splicing	9.12e-02	1.00e+00	3.398	1	11	228
GO:0043025	neuronal cell body	9.77e-02	1.00e+00	3.294	1	9	245
GO:0000166	nucleotide binding	1.03e-01	1.00e+00	3.214	1	5	259
GO:0043234	protein complex	1.17e-01	1.00e+00	3.027	1	18	295
GO:0004674	protein serine/threonine kinase activity	1.21e-01	1.00e+00	2.964	1	12	308
GO:0007411	axon guidance	1.26e-01	1.00e+00	2.914	1	13	319
GO:0005813	centrosome	1.28e-01	1.00e+00	2.882	1	14	326
GO:0007268	synaptic transmission	1.30e-01	1.00e+00	2.856	1	6	332
GO:0005925	focal adhesion	1.43e-01	1.00e+00	2.715	1	19	366
GO:0008284	positive regulation of cell proliferation	1.49e-01	1.00e+00	2.654	1	8	382
GO:0006468	protein phosphorylation	1.77e-01	1.00e+00	2.386	1	18	460
GO:0042802	identical protein binding	1.85e-01	1.00e+00	2.312	1	20	484
GO:0048471	perinuclear region of cytoplasm	1.92e-01	1.00e+00	2.260	1	13	502
GO:0042803	protein homodimerization activity	2.23e-01	1.00e+00	2.014	1	12	595
GO:0005634	nucleus	2.86e-01	1.00e+00	0.662	3	136	4559
GO:0007165	signal transduction	3.23e-01	1.00e+00	1.406	1	24	907
GO:0005654	nucleoplasm	3.74e-01	1.00e+00	1.152	1	76	1082
GO:0003677	DNA binding	4.11e-01	1.00e+00	0.981	1	28	1218
GO:0005524	ATP binding	4.32e-01	1.00e+00	0.889	1	60	1298
GO:0046872	metal ion binding	4.35e-01	1.00e+00	0.879	1	25	1307
GO:0006351	transcription, DNA-templated	4.70e-01	1.00e+00	0.733	1	31	1446
GO:0005730	nucleolus	5.16e-01	1.00e+00	0.551	1	69	1641
GO:0005886	plasma membrane	6.94e-01	1.00e+00	-0.103	1	45	2582
GO:0005737	cytoplasm	8.37e-01	1.00e+00	-0.648	1	110	3767

Wolf-ratios-Mammosphere-Adherent

int-snw-1457

Statistics

Genes (6)

Interactions (5)

Related GO terms (137)