Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.930 | 2.55e-15 | 2.75e-03 | 4.33e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
VARS | 7407 | 4 | 0.549 | 1.002 | 80 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
RPS3A | 6189 | 11 | 0.835 | 1.069 | 166 | Yes | - |
PSMA6 | 5687 | 2 | 0.691 | 0.956 | 137 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
RPL14 | 9045 | 42 | 1.250 | 1.113 | 143 | Yes | - |
TUBG1 | 7283 | 3 | 0.974 | 0.938 | 55 | Yes | - |
GSK3B | 2932 | 2 | 0.475 | 0.934 | 319 | - | Yes |
[ SGK1 ] | 6446 | 1 | -0.189 | 0.930 | 76 | - | Yes |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
SAP18 | 10284 | 8 | 1.115 | 1.069 | 57 | Yes | - |
PSMD6 | 9861 | 11 | 0.848 | 1.009 | 131 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA6 | 5687 | SGK1 | 6446 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPS3A | 6189 | SGK1 | 6446 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
GSK3B | 2932 | SGK1 | 6446 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vitro, in vivo |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
ACTB | 60 | RPS3A | 6189 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMB7 | 5695 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct |
PSMD11 | 5717 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG |
PSMA1 | 5682 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastMedium |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPS3A | 6189 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPS3A | 6189 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS3A | 6189 | SAP18 | 10284 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
ACTB | 60 | PSMA6 | 5687 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA6 | 5687 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid |
PSMA6 | 5687 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastLow |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
GSK3B | 2932 | TUBG1 | 7283 | pp | -- | int.I2D: MINT |
SGK1 | 6446 | VARS | 7407 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMA6 | 5687 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, YeastHigh, IntAct_Worm, Krogan_Core, MINT_Yeast; int.Mint: MI:0914(association) |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA2 | 5683 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
RPS11 | 6205 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
RPS3A | 6189 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
SGK1 | 6446 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD3 | 5709 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS |
PSMA6 | 5687 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA6 | 5687 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA2 | 5683 | PSMA6 | 5687 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, HPRD, Krogan_Core, Tarassov_PCA, Yu_GoldStd; int.HPRD: yeast 2-hybrid |
PSMA6 | 5687 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016071 | mRNA metabolic process | 2.73e-16 | 3.94e-12 | 5.305 | 11 | 31 | 223 |
GO:0016070 | RNA metabolic process | 8.52e-16 | 1.23e-11 | 5.157 | 11 | 32 | 247 |
GO:0016032 | viral process | 8.91e-14 | 1.28e-09 | 4.170 | 12 | 55 | 534 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.20e-13 | 1.73e-09 | 6.810 | 7 | 17 | 50 |
GO:0000502 | proteasome complex | 3.60e-13 | 5.19e-09 | 6.596 | 7 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 7.40e-13 | 1.07e-08 | 6.454 | 7 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.29e-13 | 1.19e-08 | 6.431 | 7 | 22 | 65 |
GO:0010467 | gene expression | 1.29e-12 | 1.87e-08 | 3.845 | 12 | 59 | 669 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.42e-12 | 2.05e-08 | 6.324 | 7 | 22 | 70 |
GO:0005829 | cytosol | 1.61e-12 | 2.33e-08 | 2.448 | 17 | 132 | 2496 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.74e-12 | 2.52e-08 | 6.284 | 7 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.13e-12 | 3.07e-08 | 6.244 | 7 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.35e-12 | 3.38e-08 | 6.225 | 7 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.42e-12 | 4.93e-08 | 6.150 | 7 | 23 | 79 |
GO:0042981 | regulation of apoptotic process | 4.55e-12 | 6.56e-08 | 5.417 | 8 | 24 | 150 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.02e-11 | 1.48e-07 | 5.930 | 7 | 21 | 92 |
GO:0000209 | protein polyubiquitination | 5.36e-11 | 7.73e-07 | 5.596 | 7 | 20 | 116 |
GO:0000082 | G1/S transition of mitotic cell cycle | 3.15e-10 | 4.55e-06 | 5.234 | 7 | 32 | 149 |
GO:0043066 | negative regulation of apoptotic process | 5.79e-10 | 8.36e-06 | 4.088 | 9 | 31 | 424 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.30e-10 | 1.20e-05 | 5.036 | 7 | 20 | 171 |
GO:0005839 | proteasome core complex | 5.14e-09 | 7.41e-05 | 7.476 | 4 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 6.50e-09 | 9.38e-05 | 7.398 | 4 | 8 | 19 |
GO:0000278 | mitotic cell cycle | 9.37e-09 | 1.35e-04 | 4.035 | 8 | 48 | 391 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 9.10e-08 | 1.31e-03 | 8.231 | 3 | 4 | 8 |
GO:0006915 | apoptotic process | 1.42e-07 | 2.05e-03 | 3.530 | 8 | 33 | 555 |
GO:0022624 | proteasome accessory complex | 1.10e-06 | 1.58e-02 | 7.144 | 3 | 8 | 17 |
GO:0005654 | nucleoplasm | 1.90e-06 | 2.75e-02 | 2.737 | 9 | 76 | 1082 |
GO:0019083 | viral transcription | 2.66e-06 | 3.84e-02 | 5.306 | 4 | 10 | 81 |
GO:0070062 | extracellular vesicular exosome | 3.03e-06 | 4.37e-02 | 2.002 | 12 | 104 | 2400 |
GO:0006415 | translational termination | 3.54e-06 | 5.11e-02 | 5.203 | 4 | 10 | 87 |
GO:0006414 | translational elongation | 4.63e-06 | 6.67e-02 | 5.107 | 4 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 7.22e-06 | 1.04e-01 | 4.946 | 4 | 10 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.04e-05 | 1.50e-01 | 4.813 | 4 | 11 | 114 |
GO:0019058 | viral life cycle | 1.08e-05 | 1.55e-01 | 4.801 | 4 | 13 | 115 |
GO:0022627 | cytosolic small ribosomal subunit | 1.45e-05 | 2.09e-01 | 5.946 | 3 | 4 | 39 |
GO:0006413 | translational initiation | 1.80e-05 | 2.60e-01 | 4.613 | 4 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 2.15e-05 | 3.10e-01 | 4.548 | 4 | 10 | 137 |
GO:0005838 | proteasome regulatory particle | 9.64e-05 | 1.00e+00 | 7.061 | 2 | 7 | 12 |
GO:0006412 | translation | 1.62e-04 | 1.00e+00 | 3.801 | 4 | 20 | 230 |
GO:0044267 | cellular protein metabolic process | 2.26e-04 | 1.00e+00 | 3.079 | 5 | 29 | 474 |
GO:0030529 | ribonucleoprotein complex | 3.42e-04 | 1.00e+00 | 4.424 | 3 | 8 | 112 |
GO:0005844 | polysome | 3.66e-04 | 1.00e+00 | 6.123 | 2 | 4 | 23 |
GO:0044281 | small molecule metabolic process | 4.02e-04 | 1.00e+00 | 2.212 | 7 | 58 | 1211 |
GO:0051059 | NF-kappaB binding | 4.34e-04 | 1.00e+00 | 6.002 | 2 | 2 | 25 |
GO:0003723 | RNA binding | 7.30e-04 | 1.00e+00 | 3.228 | 4 | 20 | 342 |
GO:0035639 | purine ribonucleoside triphosphate binding | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060453 | regulation of gastric acid secretion | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0000932 | cytoplasmic mRNA processing body | 2.03e-03 | 1.00e+00 | 4.891 | 2 | 3 | 54 |
GO:0005515 | protein binding | 2.10e-03 | 1.00e+00 | 0.897 | 14 | 184 | 6024 |
GO:0004832 | valine-tRNA ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0044337 | canonical Wnt signaling pathway involved in positive regulation of apoptotic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0014043 | negative regulation of neuron maturation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0071109 | superior temporal gyrus development | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:2000077 | negative regulation of type B pancreatic cell development | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0061574 | ASAP complex | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0000320 | re-entry into mitotic cell cycle | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 3 |
GO:2000466 | negative regulation of glycogen (starch) synthase activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0044027 | hypermethylation of CpG island | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0000212 | meiotic spindle organization | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0070294 | renal sodium ion absorption | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0051534 | negative regulation of NFAT protein import into nucleus | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0005200 | structural constituent of cytoskeleton | 5.64e-03 | 1.00e+00 | 4.138 | 2 | 8 | 91 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0036016 | cellular response to interleukin-3 | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:2000738 | positive regulation of stem cell differentiation | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 2 | 5 |
GO:0017081 | chloride channel regulator activity | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0005827 | polar microtubule | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0032411 | positive regulation of transporter activity | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0005813 | centrosome | 7.26e-03 | 1.00e+00 | 2.882 | 3 | 14 | 326 |
GO:0002181 | cytoplasmic translation | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0050774 | negative regulation of dendrite morphogenesis | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 3 | 6 |
GO:0010614 | negative regulation of cardiac muscle hypertrophy | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0005737 | cytoplasm | 7.54e-03 | 1.00e+00 | 1.089 | 10 | 110 | 3767 |
GO:0044822 | poly(A) RNA binding | 7.99e-03 | 1.00e+00 | 1.924 | 5 | 49 | 1056 |
GO:0000028 | ribosomal small subunit assembly | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0000930 | gamma-tubulin complex | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0005634 | nucleus | 9.34e-03 | 1.00e+00 | 0.951 | 11 | 136 | 4559 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 8 |
GO:1901030 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0045719 | negative regulation of glycogen biosynthetic process | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0035372 | protein localization to microtubule | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0005925 | focal adhesion | 9.96e-03 | 1.00e+00 | 2.715 | 3 | 19 | 366 |
GO:0006450 | regulation of translational fidelity | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0048156 | tau protein binding | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0005730 | nucleolus | 1.19e-02 | 1.00e+00 | 1.551 | 6 | 69 | 1641 |
GO:0010226 | response to lithium ion | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 10 |
GO:0030877 | beta-catenin destruction complex | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 10 |
GO:0016020 | membrane | 1.33e-02 | 1.00e+00 | 1.516 | 6 | 90 | 1681 |
GO:0032886 | regulation of microtubule-based process | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 3 | 12 |
GO:0034236 | protein kinase A catalytic subunit binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0050321 | tau-protein kinase activity | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0042273 | ribosomal large subunit biogenesis | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 4 | 13 |
GO:0031334 | positive regulation of protein complex assembly | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 13 |
GO:0030234 | enzyme regulator activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 13 |
GO:0046827 | positive regulation of protein export from nucleus | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 14 |
GO:0031333 | negative regulation of protein complex assembly | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0048168 | regulation of neuronal synaptic plasticity | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 2 | 14 |
GO:0007020 | microtubule nucleation | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0006349 | regulation of gene expression by genetic imprinting | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0048025 | negative regulation of mRNA splicing, via spliceosome | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0042176 | regulation of protein catabolic process | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 3 | 16 |
GO:0035255 | ionotropic glutamate receptor binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0007520 | myoblast fusion | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0051603 | proteolysis involved in cellular protein catabolic process | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0031625 | ubiquitin protein ligase binding | 2.04e-02 | 1.00e+00 | 3.170 | 2 | 14 | 178 |
GO:0010800 | positive regulation of peptidyl-threonine phosphorylation | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 17 |
GO:0031122 | cytoplasmic microtubule organization | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 18 |
GO:0005246 | calcium channel regulator activity | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 18 |
GO:0035145 | exon-exon junction complex | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0051090 | regulation of sequence-specific DNA binding transcription factor activity | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 20 |
GO:0001954 | positive regulation of cell-matrix adhesion | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 21 |
GO:0017080 | sodium channel regulator activity | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 21 |
GO:0030010 | establishment of cell polarity | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 21 |
GO:0030863 | cortical cytoskeleton | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 22 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 4 | 23 |
GO:0000794 | condensed nuclear chromosome | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 2 | 24 |
GO:0005977 | glycogen metabolic process | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 1 | 24 |
GO:0006611 | protein export from nucleus | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 3 | 25 |
GO:0030016 | myofibril | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 25 |
GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 26 |
GO:0015459 | potassium channel regulator activity | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 26 |
GO:0007616 | long-term memory | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 27 |
GO:0019843 | rRNA binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 4 | 27 |
GO:0000118 | histone deacetylase complex | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 28 |
GO:0019894 | kinesin binding | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 1 | 29 |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 4 | 29 |
GO:0043198 | dendritic shaft | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 1 | 29 |
GO:0032091 | negative regulation of protein binding | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 32 |
GO:0043407 | negative regulation of MAP kinase activity | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:0004175 | endopeptidase activity | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:0016301 | kinase activity | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 3 | 33 |
GO:0001837 | epithelial to mesenchymal transition | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 1 | 33 |
GO:0001085 | RNA polymerase II transcription factor binding | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 2 | 33 |
GO:0001895 | retina homeostasis | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 1 | 34 |
GO:0030017 | sarcomere | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 1 | 34 |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 3 | 35 |
GO:0032855 | positive regulation of Rac GTPase activity | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 1 | 35 |
GO:0034332 | adherens junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.52e-02 | 1.00e+00 | 4.437 | 1 | 4 | 37 |
GO:0021766 | hippocampus development | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 4 | 38 |
GO:0032092 | positive regulation of protein binding | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 3 | 38 |
GO:0070527 | platelet aggregation | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 2 | 38 |
GO:0006418 | tRNA aminoacylation for protein translation | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 9 | 42 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 3 | 44 |
GO:0021762 | substantia nigra development | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 2 | 44 |
GO:0050727 | regulation of inflammatory response | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 3 | 45 |
GO:0004674 | protein serine/threonine kinase activity | 5.55e-02 | 1.00e+00 | 2.379 | 2 | 12 | 308 |
GO:0006950 | response to stress | 5.59e-02 | 1.00e+00 | 4.123 | 1 | 2 | 46 |
GO:0045444 | fat cell differentiation | 5.71e-02 | 1.00e+00 | 4.092 | 1 | 2 | 47 |
GO:0019901 | protein kinase binding | 5.85e-02 | 1.00e+00 | 2.338 | 2 | 21 | 317 |
GO:0007411 | axon guidance | 5.91e-02 | 1.00e+00 | 2.329 | 2 | 13 | 319 |
GO:0006814 | sodium ion transport | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 1 | 49 |
GO:0022625 | cytosolic large ribosomal subunit | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 6 | 49 |
GO:0030334 | regulation of cell migration | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 2 | 50 |
GO:0045732 | positive regulation of protein catabolic process | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 3 | 50 |
GO:0000226 | microtubule cytoskeleton organization | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 3 | 52 |
GO:0007623 | circadian rhythm | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 53 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 2 | 54 |
GO:0002039 | p53 binding | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 7 | 55 |
GO:0008217 | regulation of blood pressure | 6.88e-02 | 1.00e+00 | 3.813 | 1 | 4 | 57 |
GO:0005840 | ribosome | 7.00e-02 | 1.00e+00 | 3.788 | 1 | 1 | 58 |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 7.12e-02 | 1.00e+00 | 3.764 | 1 | 2 | 59 |
GO:0005524 | ATP binding | 7.21e-02 | 1.00e+00 | 1.304 | 4 | 60 | 1298 |
GO:0008013 | beta-catenin binding | 7.23e-02 | 1.00e+00 | 3.739 | 1 | 3 | 60 |
GO:0001558 | regulation of cell growth | 7.35e-02 | 1.00e+00 | 3.715 | 1 | 2 | 61 |
GO:0071260 | cellular response to mechanical stimulus | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 5 | 65 |
GO:0034329 | cell junction assembly | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 1 | 68 |
GO:0018105 | peptidyl-serine phosphorylation | 8.27e-02 | 1.00e+00 | 3.538 | 1 | 5 | 69 |
GO:0050790 | regulation of catalytic activity | 8.27e-02 | 1.00e+00 | 3.538 | 1 | 2 | 69 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 2 | 75 |
GO:0060070 | canonical Wnt signaling pathway | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 3 | 75 |
GO:0043197 | dendritic spine | 9.76e-02 | 1.00e+00 | 3.289 | 1 | 3 | 82 |
GO:0009887 | organ morphogenesis | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 2 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 1 | 86 |
GO:0016363 | nuclear matrix | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 12 | 91 |
GO:0006928 | cellular component movement | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 7 | 91 |
GO:0001649 | osteoblast differentiation | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 6 | 92 |
GO:0006468 | protein phosphorylation | 1.11e-01 | 1.00e+00 | 1.801 | 2 | 18 | 460 |
GO:0006364 | rRNA processing | 1.11e-01 | 1.00e+00 | 3.092 | 1 | 6 | 94 |
GO:0030426 | growth cone | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 5 | 96 |
GO:0005178 | integrin binding | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 2 | 96 |
GO:0014069 | postsynaptic density | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 3 | 105 |
GO:0042127 | regulation of cell proliferation | 1.28e-01 | 1.00e+00 | 2.878 | 1 | 3 | 109 |
GO:0015630 | microtubule cytoskeleton | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 1.30e-01 | 1.00e+00 | 2.852 | 1 | 3 | 111 |
GO:0048015 | phosphatidylinositol-mediated signaling | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 7 | 114 |
GO:0006325 | chromatin organization | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 1.40e-01 | 1.00e+00 | 2.739 | 1 | 5 | 120 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.44e-01 | 1.00e+00 | 2.692 | 1 | 4 | 124 |
GO:0009615 | response to virus | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 5 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 5 | 126 |
GO:0016477 | cell migration | 1.48e-01 | 1.00e+00 | 2.646 | 1 | 5 | 128 |
GO:0000790 | nuclear chromatin | 1.49e-01 | 1.00e+00 | 2.635 | 1 | 9 | 129 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.57e-01 | 1.00e+00 | 2.559 | 1 | 9 | 136 |
GO:0016887 | ATPase activity | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.64e-01 | 1.00e+00 | 2.486 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.66e-01 | 1.00e+00 | 2.466 | 1 | 7 | 145 |
GO:0045087 | innate immune response | 1.69e-01 | 1.00e+00 | 1.427 | 2 | 24 | 596 |
GO:0034220 | ion transmembrane transport | 1.71e-01 | 1.00e+00 | 2.427 | 1 | 4 | 149 |
GO:0006974 | cellular response to DNA damage stimulus | 1.73e-01 | 1.00e+00 | 2.408 | 1 | 8 | 151 |
GO:0045121 | membrane raft | 1.78e-01 | 1.00e+00 | 2.361 | 1 | 8 | 156 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.78e-01 | 1.00e+00 | 2.361 | 1 | 9 | 156 |
GO:0006397 | mRNA processing | 1.82e-01 | 1.00e+00 | 2.324 | 1 | 2 | 160 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.87e-01 | 1.00e+00 | 2.280 | 1 | 7 | 165 |
GO:0030424 | axon | 1.88e-01 | 1.00e+00 | 2.271 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 12 | 168 |
GO:0016607 | nuclear speck | 1.94e-01 | 1.00e+00 | 2.220 | 1 | 3 | 172 |
GO:0003714 | transcription corepressor activity | 2.00e-01 | 1.00e+00 | 2.170 | 1 | 8 | 178 |
GO:0032403 | protein complex binding | 2.05e-01 | 1.00e+00 | 2.130 | 1 | 10 | 183 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 2.11e-01 | 1.00e+00 | 2.084 | 1 | 12 | 189 |
GO:0003924 | GTPase activity | 2.19e-01 | 1.00e+00 | 2.024 | 1 | 12 | 197 |
GO:0006184 | GTP catabolic process | 2.36e-01 | 1.00e+00 | 1.905 | 1 | 12 | 214 |
GO:0008380 | RNA splicing | 2.49e-01 | 1.00e+00 | 1.813 | 1 | 11 | 228 |
GO:0043025 | neuronal cell body | 2.66e-01 | 1.00e+00 | 1.710 | 1 | 9 | 245 |
GO:0004842 | ubiquitin-protein transferase activity | 2.75e-01 | 1.00e+00 | 1.652 | 1 | 6 | 255 |
GO:0006281 | DNA repair | 2.80e-01 | 1.00e+00 | 1.618 | 1 | 18 | 261 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 2.83e-01 | 1.00e+00 | 1.602 | 1 | 8 | 264 |
GO:0043065 | positive regulation of apoptotic process | 2.87e-01 | 1.00e+00 | 1.580 | 1 | 10 | 268 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.88e-01 | 1.00e+00 | 1.575 | 1 | 15 | 269 |
GO:0042493 | response to drug | 3.01e-01 | 1.00e+00 | 1.496 | 1 | 13 | 284 |
GO:0005856 | cytoskeleton | 3.07e-01 | 1.00e+00 | 1.461 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 3.08e-01 | 1.00e+00 | 1.456 | 1 | 15 | 292 |
GO:0016567 | protein ubiquitination | 3.11e-01 | 1.00e+00 | 1.442 | 1 | 5 | 295 |
GO:0043234 | protein complex | 3.11e-01 | 1.00e+00 | 1.442 | 1 | 18 | 295 |
GO:0030154 | cell differentiation | 3.16e-01 | 1.00e+00 | 1.413 | 1 | 5 | 301 |
GO:0035556 | intracellular signal transduction | 3.18e-01 | 1.00e+00 | 1.403 | 1 | 9 | 303 |
GO:0005525 | GTP binding | 3.24e-01 | 1.00e+00 | 1.370 | 1 | 12 | 310 |
GO:0005739 | mitochondrion | 3.57e-01 | 1.00e+00 | 0.683 | 2 | 28 | 998 |
GO:0007155 | cell adhesion | 3.73e-01 | 1.00e+00 | 1.119 | 1 | 6 | 369 |
GO:0006508 | proteolysis | 3.80e-01 | 1.00e+00 | 1.084 | 1 | 9 | 378 |
GO:0055085 | transmembrane transport | 4.24e-01 | 1.00e+00 | 0.881 | 1 | 10 | 435 |
GO:0007596 | blood coagulation | 4.39e-01 | 1.00e+00 | 0.816 | 1 | 18 | 455 |
GO:0048471 | perinuclear region of cytoplasm | 4.72e-01 | 1.00e+00 | 0.675 | 1 | 13 | 502 |
GO:0005789 | endoplasmic reticulum membrane | 5.16e-01 | 1.00e+00 | 0.491 | 1 | 16 | 570 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 6.37e-01 | 1.00e+00 | 0.022 | 1 | 19 | 789 |
GO:0005886 | plasma membrane | 6.50e-01 | 1.00e+00 | -0.103 | 3 | 45 | 2582 |
GO:0005615 | extracellular space | 7.10e-01 | 1.00e+00 | -0.256 | 1 | 17 | 957 |
GO:0008270 | zinc ion binding | 7.25e-01 | 1.00e+00 | -0.315 | 1 | 12 | 997 |
GO:0006351 | transcription, DNA-templated | 8.51e-01 | 1.00e+00 | -0.852 | 1 | 31 | 1446 |