int-snw-10056

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.958 2.11e-16 1.50e-03 2.78e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-10056 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RBX1 9978 971.1851.151139Yes-
PSMA2 5683 601.0931.10689Yes-
PSMC3 5702 90.7191.002255Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
VARS 7407 40.5491.00280Yes-
ATP6V1B2 526 440.8811.076278--
RPSA 3921 1561.3271.151152Yes-
RPA2 6118 981.2501.15169Yes-
CDC16 8881 250.9501.02080Yes-
EEF2 1938 270.8901.043301Yes-
PSMD3 5709 570.9861.106146Yes-
RPS11 6205 360.9931.113175Yes-
CLTC 1213 350.8841.138247Yes-
RPL14 9045 421.2501.113143Yes-
ACTB 60 1671.1531.151587Yes-
PSMD11 5717 1211.0951.106183Yes-
[ FARSB ] 10056 10.0990.95831--
HSPD1 3329 350.9131.035286Yes-

Interactions (46)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 CDC16 8881 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMC3 5702 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
PSMC3 5702 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
VARS 7407 FARSB 10056 pp -- int.I2D: Krogan_NonCore
PSMA1 5682 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast, YeastLow
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMC3 5702 pp -- int.I2D: YeastLow, BioGrid_Yeast
ATP6V1B2 526 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 FARSB 10056 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMC3 5702 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
PSMC3 5702 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMC3 5702 VARS 7407 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPSA 3921 PSMC3 5702 pp -- int.I2D: BioGrid_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMC3 5702 FARSB 10056 pp -- int.I2D: BioGrid_Yeast

Related GO terms (265)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005829cytosol2.93e-134.23e-092.453181322496
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.31e-121.89e-086.35372265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.24e-123.23e-086.24672270
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.36e-124.84e-086.16672274
GO:0010467gene expression3.37e-124.85e-083.7671259669
GO:0016071mRNA metabolic process3.47e-125.01e-084.937931223
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.39e-127.77e-086.07272379
GO:0016070RNA metabolic process8.72e-121.26e-074.790932247
GO:0016032viral process9.35e-121.35e-073.9671155534
GO:0006521regulation of cellular amino acid metabolic process3.34e-114.81e-076.50961750
GO:0000502proteasome complex8.45e-111.22e-066.29561758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.56e-102.25e-066.15361964
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent3.22e-104.65e-065.98362072
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I4.15e-105.98e-065.92462075
GO:0000082G1/S transition of mitotic cell cycle4.95e-107.14e-065.156732149
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.45e-092.09e-055.63062192
GO:0000209protein polyubiquitination5.92e-098.54e-055.295620116
GO:0000278mitotic cell cycle1.58e-082.28e-043.957848391
GO:0042981regulation of apoptotic process2.78e-084.01e-044.924624150
GO:0034641cellular nitrogen compound metabolic process6.07e-088.76e-044.735620171
GO:0005654nucleoplasm2.68e-073.86e-032.81110761082
GO:0043066negative regulation of apoptotic process6.70e-079.67e-033.648731424
GO:0070062extracellular vesicular exosome7.29e-071.05e-022.040131042400
GO:0022624proteasome accessory complex1.30e-061.88e-027.0663817
GO:0005839proteasome core complex1.56e-062.25e-026.9833818
GO:0016020membrane1.62e-062.33e-022.31211901681
GO:0004298threonine-type endopeptidase activity1.85e-062.67e-026.9053819
GO:0006414translational elongation5.83e-068.41e-025.02941393
GO:0006412translation9.57e-061.38e-014.045520230
GO:0019773proteasome core complex, alpha-subunit complex4.58e-056.61e-017.568248
GO:0006915apoptotic process5.58e-058.05e-013.037633555
GO:0005838proteasome regulatory particle1.08e-041.00e+006.9832712
GO:0019083viral transcription1.55e-041.00e+004.81331081
GO:0006415translational termination1.92e-041.00e+004.71031087
GO:0044267cellular protein metabolic process2.98e-041.00e+003.001529474
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.24e-041.00e+004.453310104
GO:0005844polysome4.09e-041.00e+006.0452423
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4.25e-041.00e+004.320311114
GO:0019058viral life cycle4.36e-041.00e+004.308313115
GO:0006413translational initiation6.38e-041.00e+004.120317131
GO:0033572transferrin transport7.00e-041.00e+005.6612530
GO:0003735structural constituent of ribosome7.27e-041.00e+004.055310137
GO:0005515protein binding1.09e-031.00e+000.919151846024
GO:0022627cytosolic small ribosomal subunit1.18e-031.00e+005.2832439
GO:0002842positive regulation of T cell mediated immune response to tumor cell1.32e-031.00e+009.568111
GO:0048291isotype switching to IgG isotypes1.32e-031.00e+009.568111
GO:0002368B cell cytokine production1.32e-031.00e+009.568111
GO:0006418tRNA aminoacylation for protein translation1.37e-031.00e+005.1762942
GO:0044822poly(A) RNA binding1.80e-031.00e+002.1096491056
GO:0003725double-stranded RNA binding2.10e-031.00e+004.8682552
GO:0000932cytoplasmic mRNA processing body2.26e-031.00e+004.8132354
GO:0004832valine-tRNA ligase activity2.63e-031.00e+008.568112
GO:0006407rRNA export from nucleus2.63e-031.00e+008.568112
GO:0006438valyl-tRNA aminoacylation2.63e-031.00e+008.568112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.63e-031.00e+008.568112
GO:0005055laminin receptor activity2.63e-031.00e+008.568112
GO:0003697single-stranded DNA binding3.56e-031.00e+004.4812568
GO:0044281small molecule metabolic process3.61e-031.00e+001.9116581211
GO:1900126negative regulation of hyaluronan biosynthetic process3.95e-031.00e+007.983123
GO:0006458'de novo' protein folding3.95e-031.00e+007.983113
GO:0006432phenylalanyl-tRNA aminoacylation3.95e-031.00e+007.983113
GO:0030135coated vesicle3.95e-031.00e+007.983113
GO:0071439clathrin complex3.95e-031.00e+007.983123
GO:0005524ATP binding5.10e-031.00e+001.8116601298
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.26e-031.00e+007.568114
GO:003068690S preribosome5.26e-031.00e+007.568114
GO:0032051clathrin light chain binding5.26e-031.00e+007.568114
GO:0019788NEDD8 ligase activity5.26e-031.00e+007.568114
GO:0004826phenylalanine-tRNA ligase activity5.26e-031.00e+007.568114
GO:0031467Cul7-RING ubiquitin ligase complex5.26e-031.00e+007.568114
GO:1903077negative regulation of protein localization to plasma membrane5.26e-031.00e+007.568114
GO:0042470melanosome6.28e-031.00e+004.0602991
GO:0001649osteoblast differentiation6.41e-031.00e+004.0452692
GO:0043234protein complex6.44e-031.00e+002.949318295
GO:0031465Cul4B-RING E3 ubiquitin ligase complex6.57e-031.00e+007.246135
GO:2000001regulation of DNA damage checkpoint6.57e-031.00e+007.246115
GO:0031461cullin-RING ubiquitin ligase complex6.57e-031.00e+007.246115
GO:0043248proteasome assembly6.57e-031.00e+007.246115
GO:0046696lipopolysaccharide receptor complex6.57e-031.00e+007.246115
GO:0030891VCB complex6.57e-031.00e+007.246125
GO:0000730DNA recombinase assembly6.57e-031.00e+007.246115
GO:0019901protein kinase binding7.85e-031.00e+002.845321317
GO:0003688DNA replication origin binding7.88e-031.00e+006.983126
GO:0030130clathrin coat of trans-Golgi network vesicle7.88e-031.00e+006.983136
GO:0030118clathrin coat7.88e-031.00e+006.983126
GO:0031466Cul5-RING ubiquitin ligase complex7.88e-031.00e+006.983116
GO:0030957Tat protein binding7.88e-031.00e+006.983136
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex7.88e-031.00e+006.983116
GO:0000028ribosomal small subunit assembly9.19e-031.00e+006.761117
GO:0002161aminoacyl-tRNA editing activity9.19e-031.00e+006.761127
GO:0031462Cul2-RING ubiquitin ligase complex9.19e-031.00e+006.761127
GO:0033180proton-transporting V-type ATPase, V1 domain9.19e-031.00e+006.761127
GO:0030132clathrin coat of coated pit9.19e-031.00e+006.761127
GO:0030529ribonucleoprotein complex9.38e-031.00e+003.76128112
GO:0005819spindle9.38e-031.00e+003.76127112
GO:0003723RNA binding9.66e-031.00e+002.735320342
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.05e-021.00e+006.568128
GO:0070688MLL5-L complex1.05e-021.00e+006.568118
GO:0045116protein neddylation1.05e-021.00e+006.568128
GO:0051604protein maturation1.05e-021.00e+006.568118
GO:0005925focal adhesion1.16e-021.00e+002.637319366
GO:0006450regulation of translational fidelity1.18e-021.00e+006.398129
GO:0008494translation activator activity1.18e-021.00e+006.398119
GO:0010569regulation of double-strand break repair via homologous recombination1.31e-021.00e+006.2461110
GO:0043032positive regulation of macrophage activation1.31e-021.00e+006.2461110
GO:0032727positive regulation of interferon-alpha production1.44e-021.00e+006.1091111
GO:0031571mitotic G1 DNA damage checkpoint1.44e-021.00e+006.1091411
GO:0016887ATPase activity1.44e-021.00e+003.43927140
GO:0061024membrane organization1.53e-021.00e+003.38827145
GO:0042273ribosomal large subunit biogenesis1.70e-021.00e+005.8681413
GO:0005662DNA replication factor A complex1.70e-021.00e+005.8681113
GO:0030234enzyme regulator activity1.70e-021.00e+005.8681313
GO:0001530lipopolysaccharide binding1.70e-021.00e+005.8681313
GO:0051131chaperone-mediated protein complex assembly1.70e-021.00e+005.8681113
GO:0035267NuA4 histone acetyltransferase complex1.83e-021.00e+005.7611414
GO:0042026protein refolding1.96e-021.00e+005.6611215
GO:0046034ATP metabolic process1.96e-021.00e+005.6611115
GO:0046961proton-transporting ATPase activity, rotational mechanism1.96e-021.00e+005.6611315
GO:0042176regulation of protein catabolic process2.09e-021.00e+005.5681316
GO:0050998nitric-oxide synthase binding2.09e-021.00e+005.5681116
GO:0003746translation elongation factor activity2.22e-021.00e+005.4811317
GO:0050870positive regulation of T cell activation2.22e-021.00e+005.4811117
GO:0031625ubiquitin protein ligase binding2.26e-021.00e+003.092214178
GO:0035861site of double-strand break2.35e-021.00e+005.3981118
GO:0007088regulation of mitosis2.35e-021.00e+005.3981118
GO:1903506regulation of nucleic acid-templated transcription2.35e-021.00e+005.3981118
GO:0015078hydrogen ion transmembrane transporter activity2.48e-021.00e+005.3201319
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.48e-021.00e+005.3201119
GO:0048863stem cell differentiation2.48e-021.00e+005.3201119
GO:0032733positive regulation of interleukin-10 production2.48e-021.00e+005.3201119
GO:0005680anaphase-promoting complex2.60e-021.00e+005.2461420
GO:0006298mismatch repair2.60e-021.00e+005.2461320
GO:0042100B cell proliferation2.73e-021.00e+005.1761121
GO:0000718nucleotide-excision repair, DNA damage removal2.73e-021.00e+005.1761421
GO:0032201telomere maintenance via semi-conservative replication2.73e-021.00e+005.1761521
GO:0006297nucleotide-excision repair, DNA gap filling2.86e-021.00e+005.1091322
GO:0030863cortical cytoskeleton2.86e-021.00e+005.1091122
GO:0036464cytoplasmic ribonucleoprotein granule2.86e-021.00e+005.1091422
GO:0031463Cul3-RING ubiquitin ligase complex2.99e-021.00e+005.0451323
GO:0043236laminin binding2.99e-021.00e+005.0451123
GO:0006513protein monoubiquitination2.99e-021.00e+005.0451123
GO:0043044ATP-dependent chromatin remodeling2.99e-021.00e+005.0451423
GO:0000722telomere maintenance via recombination3.24e-021.00e+004.9241525
GO:0042113B cell activation3.24e-021.00e+004.9241225
GO:0032735positive regulation of interleukin-12 production3.24e-021.00e+004.9241125
GO:0070979protein K11-linked ubiquitination3.37e-021.00e+004.8681626
GO:0015991ATP hydrolysis coupled proton transport3.37e-021.00e+004.8681426
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.37e-021.00e+004.8681326
GO:0019843rRNA binding3.50e-021.00e+004.8131327
GO:0043022ribosome binding3.50e-021.00e+004.8131327
GO:0031492nucleosomal DNA binding3.50e-021.00e+004.8131427
GO:0007067mitotic nuclear division3.54e-021.00e+002.742214227
GO:0030669clathrin-coated endocytic vesicle membrane3.63e-021.00e+004.7611428
GO:0019894kinesin binding3.63e-021.00e+004.7611128
GO:0019005SCF ubiquitin ligase complex3.75e-021.00e+004.7101129
GO:0015992proton transport3.75e-021.00e+004.7101329
GO:0006271DNA strand elongation involved in DNA replication3.88e-021.00e+004.6611730
GO:0031623receptor internalization4.01e-021.00e+004.6141231
GO:0007094mitotic spindle assembly checkpoint4.01e-021.00e+004.6141431
GO:1903507negative regulation of nucleic acid-templated transcription4.13e-021.00e+004.5681232
GO:0051701interaction with host4.13e-021.00e+004.5681432
GO:0032588trans-Golgi network membrane4.39e-021.00e+004.4811234
GO:0001895retina homeostasis4.39e-021.00e+004.4811134
GO:0005876spindle microtubule4.39e-021.00e+004.4811234
GO:0006281DNA repair4.56e-021.00e+002.540218261
GO:0034332adherens junction organization4.64e-021.00e+004.3981136
GO:0090382phagosome maturation4.64e-021.00e+004.3981536
GO:0032755positive regulation of interleukin-6 production4.64e-021.00e+004.3981236
GO:0051084'de novo' posttranslational protein folding4.77e-021.00e+004.3591437
GO:0006284base-excision repair4.77e-021.00e+004.3591337
GO:0005902microvillus4.89e-021.00e+004.3201238
GO:0070527platelet aggregation4.89e-021.00e+004.3201238
GO:0000781chromosome, telomeric region5.02e-021.00e+004.2831339
GO:0032729positive regulation of interferon-gamma production5.02e-021.00e+004.2831239
GO:0042110T cell activation5.39e-021.00e+004.1761342
GO:0030136clathrin-coated vesicle5.39e-021.00e+004.1761442
GO:0006892post-Golgi vesicle-mediated transport5.52e-021.00e+004.1421343
GO:0006200ATP catabolic process5.57e-021.00e+002.378215292
GO:0021762substantia nigra development5.64e-021.00e+004.1091244
GO:0045727positive regulation of translation5.64e-021.00e+004.1091344
GO:0006283transcription-coupled nucleotide-excision repair5.89e-021.00e+004.0451746
GO:0022625cytosolic large ribosomal subunit6.27e-021.00e+003.9531649
GO:0003684damaged DNA binding6.27e-021.00e+003.9531749
GO:0006986response to unfolded protein6.39e-021.00e+003.9241250
GO:0005905coated pit6.39e-021.00e+003.9241350
GO:0006879cellular iron ion homeostasis6.51e-021.00e+003.8961451
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.76e-021.00e+003.8401553
GO:0005813centrosome6.77e-021.00e+002.219214326
GO:0045216cell-cell junction organization6.88e-021.00e+003.8131254
GO:0002244hematopoietic progenitor cell differentiation6.88e-021.00e+003.8131154
GO:0002039p53 binding7.01e-021.00e+003.7871755
GO:0000724double-strand break repair via homologous recombination7.01e-021.00e+003.7871355
GO:0000723telomere maintenance7.13e-021.00e+003.7611656
GO:0012505endomembrane system7.13e-021.00e+003.7611256
GO:0005840ribosome7.37e-021.00e+003.7101158
GO:0051087chaperone binding7.50e-021.00e+003.6861659
GO:0006302double-strand break repair7.86e-021.00e+003.6141462
GO:0019903protein phosphatase binding7.86e-021.00e+003.6141462
GO:0030141secretory granule7.86e-021.00e+003.6141262
GO:0006289nucleotide-excision repair8.59e-021.00e+003.48111168
GO:0034329cell junction assembly8.59e-021.00e+003.4811168
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis9.32e-021.00e+003.3591674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process9.44e-021.00e+003.3391275
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process9.68e-021.00e+003.3011777
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.00e-011.00e+003.2461380
GO:0001726ruffle1.00e-011.00e+003.2461480
GO:0006898receptor-mediated endocytosis1.05e-011.00e+003.1761384
GO:0047485protein N-terminus binding1.07e-011.00e+003.1421586
GO:0050821protein stabilization1.10e-011.00e+003.1091288
GO:0016605PML body1.10e-011.00e+003.1091388
GO:0005634nucleus1.11e-011.00e+000.58491364559
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.12e-011.00e+003.0761790
GO:0006928cellular component movement1.13e-011.00e+003.0601791
GO:0005200structural constituent of cytoskeleton1.13e-011.00e+003.0601891
GO:0071456cellular response to hypoxia1.15e-011.00e+003.0451692
GO:0051082unfolded protein binding1.16e-011.00e+003.0291593
GO:0006364rRNA processing1.17e-011.00e+003.0141694
GO:0014069postsynaptic density1.30e-011.00e+002.85413105
GO:0015630microtubule cytoskeleton1.35e-011.00e+002.78714110
GO:0072562blood microparticle1.37e-011.00e+002.77413111
GO:0006325chromatin organization1.45e-011.00e+002.68615118
GO:0007219Notch signaling pathway1.47e-011.00e+002.66115120
GO:0006260DNA replication1.48e-011.00e+002.64919121
GO:0009615response to virus1.54e-011.00e+002.59115126
GO:0006511ubiquitin-dependent protein catabolic process1.54e-011.00e+002.59115126
GO:0000790nuclear chromatin1.57e-011.00e+002.55719129
GO:0031982vesicle1.59e-011.00e+002.53519131
GO:0005730nucleolus1.63e-011.00e+000.8884691641
GO:0008286insulin receptor signaling pathway1.71e-011.00e+002.41817142
GO:0006457protein folding1.73e-011.00e+002.40817143
GO:0010628positive regulation of gene expression1.76e-011.00e+002.37815146
GO:0005198structural molecule activity1.80e-011.00e+002.33915150
GO:0005769early endosome1.82e-011.00e+002.32012152
GO:0000287magnesium ion binding1.95e-011.00e+002.21114164
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.96e-011.00e+002.20217165
GO:0030424axon1.98e-011.00e+002.19314166
GO:0006886intracellular protein transport2.03e-011.00e+002.15015171
GO:0005737cytoplasm2.07e-011.00e+000.49671103767
GO:0003714transcription corepressor activity2.10e-011.00e+002.09218178
GO:0032403protein complex binding2.16e-011.00e+002.052110183
GO:0003924GTPase activity2.30e-011.00e+001.946112197
GO:0005765lysosomal membrane2.36e-011.00e+001.90315203
GO:0006184GTP catabolic process2.47e-011.00e+001.827112214
GO:0005759mitochondrial matrix2.61e-011.00e+001.735114228
GO:0003713transcription coactivator activity2.70e-011.00e+001.679110237
GO:0004842ubiquitin-protein transferase activity2.88e-011.00e+001.57416255
GO:0043065positive regulation of apoptotic process3.00e-011.00e+001.502110268
GO:0005743mitochondrial inner membrane3.08e-011.00e+001.45418277
GO:0019899enzyme binding3.08e-011.00e+001.454112277
GO:0005856cytoskeleton3.21e-011.00e+001.383112291
GO:0016567protein ubiquitination3.25e-011.00e+001.36415295
GO:0005525GTP binding3.38e-011.00e+001.292112310
GO:0043231intracellular membrane-bounded organelle3.45e-011.00e+001.25519318
GO:0007411axon guidance3.46e-011.00e+001.251113319
GO:0008283cell proliferation3.54e-011.00e+001.211114328
GO:0005615extracellular space3.62e-011.00e+000.666217957
GO:0005739mitochondrion3.82e-011.00e+000.605228998
GO:0007155cell adhesion3.89e-011.00e+001.04116369
GO:0009986cell surface4.16e-011.00e+000.917111402
GO:0055085transmembrane transport4.41e-011.00e+000.803110435
GO:0005886plasma membrane4.50e-011.00e+000.2344452582
GO:0007596blood coagulation4.56e-011.00e+000.738118455
GO:0045087innate immune response5.52e-011.00e+000.349124596
GO:0008270zinc ion binding7.44e-011.00e+00-0.393112997
GO:0016021integral component of membrane9.40e-011.00e+00-1.3851271982