Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.950 | 4.36e-16 | 1.79e-03 | 3.17e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
EIF2S2 | 8894 | 27 | 1.075 | 1.138 | 81 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
[ ERBB2 ] | 2064 | 1 | 0.004 | 0.950 | 156 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
KPNB1 | 3837 | 6 | 0.613 | 1.017 | 296 | Yes | - |
ITK | 3702 | 2 | 0.602 | 0.950 | 39 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
CLTC | 1213 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0914(association) |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ERBB2 | 2064 | ITK | 3702 | pp | -- | int.I2D: JonesErbB1, MINT; int.Mint: MI:0407(direct interaction) |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
CLTC | 1213 | ERBB2 | 2064 | pp | -- | int.Intact: MI:0914(association) |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
KPNB1 | 3837 | PSMA2 | 5683 | pp | -- | int.I2D: Krogan_NonCore, YeastLow |
ACTB | 60 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
CLTC | 1213 | EIF2S2 | 8894 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | KPNB1 | 3837 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
ACTB | 60 | ERBB2 | 2064 | pp | -- | int.Intact: MI:0915(physical association), MI:0403(colocalization), MI:0914(association) |
KPNB1 | 3837 | PSMD11 | 5717 | pp | -- | int.I2D: Krogan_NonCore |
KPNB1 | 3837 | PSMA1 | 5682 | pp | -- | int.I2D: YeastLow |
ERBB2 | 2064 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association), MI:0403(colocalization) |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 1.19e-09 | 1.72e-05 | 6.587 | 5 | 17 | 50 |
GO:0000502 | proteasome complex | 2.57e-09 | 3.70e-05 | 6.373 | 5 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 4.26e-09 | 6.14e-05 | 6.231 | 5 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.61e-09 | 6.65e-05 | 6.209 | 5 | 22 | 65 |
GO:0000082 | G1/S transition of mitotic cell cycle | 5.09e-09 | 7.35e-05 | 5.275 | 6 | 32 | 149 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.73e-09 | 9.71e-05 | 6.102 | 5 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 7.78e-09 | 1.12e-04 | 6.061 | 5 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.94e-09 | 1.29e-04 | 6.022 | 5 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 9.58e-09 | 1.38e-04 | 6.002 | 5 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.25e-08 | 1.80e-04 | 5.927 | 5 | 23 | 79 |
GO:0016032 | viral process | 1.72e-08 | 2.47e-04 | 3.848 | 8 | 55 | 534 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 2.70e-08 | 3.90e-04 | 5.708 | 5 | 21 | 92 |
GO:0016071 | mRNA metabolic process | 5.69e-08 | 8.21e-04 | 4.693 | 6 | 31 | 223 |
GO:0000209 | protein polyubiquitination | 8.69e-08 | 1.25e-03 | 5.373 | 5 | 20 | 116 |
GO:0016070 | RNA metabolic process | 1.04e-07 | 1.51e-03 | 4.546 | 6 | 32 | 247 |
GO:0005829 | cytosol | 1.91e-07 | 2.76e-03 | 2.209 | 12 | 132 | 2496 |
GO:0005654 | nucleoplasm | 2.41e-07 | 3.48e-03 | 3.000 | 9 | 76 | 1082 |
GO:0042981 | regulation of apoptotic process | 3.14e-07 | 4.53e-03 | 5.002 | 5 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 6.03e-07 | 8.69e-03 | 4.813 | 5 | 20 | 171 |
GO:0005839 | proteasome core complex | 7.36e-07 | 1.06e-02 | 7.324 | 3 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 8.73e-07 | 1.26e-02 | 7.246 | 3 | 8 | 19 |
GO:0000278 | mitotic cell cycle | 1.55e-06 | 2.24e-02 | 3.883 | 6 | 48 | 391 |
GO:0010467 | gene expression | 2.08e-06 | 3.00e-02 | 3.331 | 7 | 59 | 669 |
GO:0006915 | apoptotic process | 1.18e-05 | 1.70e-01 | 3.378 | 6 | 33 | 555 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.82e-05 | 4.06e-01 | 7.909 | 2 | 4 | 8 |
GO:0043066 | negative regulation of apoptotic process | 5.05e-05 | 7.28e-01 | 3.503 | 5 | 31 | 424 |
GO:0005838 | proteasome regulatory particle | 6.62e-05 | 9.55e-01 | 7.324 | 2 | 7 | 12 |
GO:0044281 | small molecule metabolic process | 1.02e-04 | 1.00e+00 | 2.475 | 7 | 58 | 1211 |
GO:0022624 | proteasome accessory complex | 1.36e-04 | 1.00e+00 | 6.822 | 2 | 8 | 17 |
GO:0070062 | extracellular vesicular exosome | 1.84e-04 | 1.00e+00 | 1.850 | 9 | 104 | 2400 |
GO:0005515 | protein binding | 4.61e-04 | 1.00e+00 | 1.053 | 13 | 184 | 6024 |
GO:0001042 | RNA polymerase I core binding | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0019903 | protein phosphatase binding | 1.84e-03 | 1.00e+00 | 4.955 | 2 | 4 | 62 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0002176 | male germ cell proliferation | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0032633 | interleukin-4 production | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0001865 | NK T cell differentiation | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 3 |
GO:0071439 | clathrin complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0043125 | ErbB-3 class receptor binding | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0033088 | negative regulation of immature T cell proliferation in thymus | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0006610 | ribosomal protein import into nucleus | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0071782 | endoplasmic reticulum tubular network | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0016020 | membrane | 4.89e-03 | 1.00e+00 | 1.779 | 6 | 90 | 1681 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 3 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0005634 | nucleus | 5.55e-03 | 1.00e+00 | 1.077 | 10 | 136 | 4559 |
GO:0019058 | viral life cycle | 6.18e-03 | 1.00e+00 | 4.064 | 2 | 13 | 115 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 3 | 6 |
GO:0006101 | citrate metabolic process | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0030118 | clathrin coat | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 3 | 6 |
GO:0045943 | positive regulation of transcription from RNA polymerase I promoter | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
GO:0030132 | clathrin coat of coated pit | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
GO:0006413 | translational initiation | 7.96e-03 | 1.00e+00 | 3.876 | 2 | 17 | 131 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 8.07e-03 | 1.00e+00 | 3.865 | 2 | 7 | 132 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 8 |
GO:0008139 | nuclear localization sequence binding | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 3 | 9 |
GO:0004716 | receptor signaling protein tyrosine kinase activity | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0032609 | interferon-gamma production | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0007167 | enzyme linked receptor protein signaling pathway | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0061024 | membrane organization | 9.67e-03 | 1.00e+00 | 3.729 | 2 | 7 | 145 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 1 | 10 |
GO:0045945 | positive regulation of transcription from RNA polymerase III promoter | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 4 | 11 |
GO:0044267 | cellular protein metabolic process | 1.20e-02 | 1.00e+00 | 2.605 | 3 | 29 | 474 |
GO:0032886 | regulation of microtubule-based process | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 12 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.28e-02 | 1.00e+00 | 3.517 | 2 | 12 | 168 |
GO:0005662 | DNA replication factor A complex | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 3 | 13 |
GO:0031625 | ubiquitin protein ligase binding | 1.43e-02 | 1.00e+00 | 3.433 | 2 | 14 | 178 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 4 | 14 |
GO:0006607 | NLS-bearing protein import into nucleus | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 3 | 14 |
GO:0042176 | regulation of protein catabolic process | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0075733 | intracellular transport of virus | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 3 | 17 |
GO:0006309 | apoptotic DNA fragmentation | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 17 |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 17 |
GO:0035861 | site of double-strand break | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
GO:0008045 | motor neuron axon guidance | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
GO:0044822 | poly(A) RNA binding | 2.03e-02 | 1.00e+00 | 1.865 | 4 | 49 | 1056 |
GO:0006298 | mismatch repair | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 3 | 20 |
GO:0005730 | nucleolus | 2.14e-02 | 1.00e+00 | 1.551 | 5 | 69 | 1641 |
GO:0014065 | phosphatidylinositol 3-kinase signaling | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 2 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 4 | 21 |
GO:0032201 | telomere maintenance via semi-conservative replication | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 5 | 21 |
GO:0045087 | innate immune response | 2.20e-02 | 1.00e+00 | 2.275 | 3 | 24 | 596 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 4 | 22 |
GO:0006412 | translation | 2.32e-02 | 1.00e+00 | 3.064 | 2 | 20 | 230 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
GO:0048709 | oligodendrocyte differentiation | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 4 | 23 |
GO:0005844 | polysome | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 4 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 7 | 24 |
GO:0045765 | regulation of angiogenesis | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 24 |
GO:0000060 | protein import into nucleus, translocation | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 5 | 24 |
GO:0007422 | peripheral nervous system development | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
GO:0001816 | cytokine production | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 3 | 25 |
GO:0000722 | telomere maintenance via recombination | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 5 | 25 |
GO:0008536 | Ran GTPase binding | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
GO:0019838 | growth factor binding | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 3 | 26 |
GO:0043022 | ribosome binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 4 | 27 |
GO:0023014 | signal transduction by phosphorylation | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0006099 | tricarboxylic acid cycle | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 4 | 28 |
GO:0002250 | adaptive immune response | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0006281 | DNA repair | 2.93e-02 | 1.00e+00 | 2.881 | 2 | 18 | 261 |
GO:0019005 | SCF ubiquitin ligase complex | 2.98e-02 | 1.00e+00 | 5.051 | 1 | 1 | 29 |
GO:0006606 | protein import into nucleus | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
GO:0033572 | transferrin transport | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 5 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 7 | 30 |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
GO:0031623 | receptor internalization | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 2 | 31 |
GO:0019899 | enzyme binding | 3.27e-02 | 1.00e+00 | 2.795 | 2 | 12 | 277 |
GO:0007528 | neuromuscular junction development | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 32 |
GO:0032588 | trans-Golgi network membrane | 3.48e-02 | 1.00e+00 | 4.822 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 3.48e-02 | 1.00e+00 | 4.822 | 1 | 1 | 34 |
GO:0042552 | myelination | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 1 | 35 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 3 | 35 |
GO:0043234 | protein complex | 3.67e-02 | 1.00e+00 | 2.705 | 2 | 18 | 295 |
GO:0034332 | adherens junction organization | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.78e-02 | 1.00e+00 | 4.700 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 3.78e-02 | 1.00e+00 | 4.700 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 2 | 38 |
GO:0000781 | chromosome, telomeric region | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 3 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 39 |
GO:0045785 | positive regulation of cell adhesion | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 4 | 40 |
GO:0019901 | protein kinase binding | 4.19e-02 | 1.00e+00 | 2.601 | 2 | 21 | 317 |
GO:0007411 | axon guidance | 4.24e-02 | 1.00e+00 | 2.592 | 2 | 13 | 319 |
GO:0042110 | T cell activation | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 3 | 42 |
GO:0030136 | clathrin-coated vesicle | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 4 | 42 |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 4 | 42 |
GO:0006892 | post-Golgi vesicle-mediated transport | 4.38e-02 | 1.00e+00 | 4.483 | 1 | 3 | 43 |
GO:0021762 | substantia nigra development | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 2 | 44 |
GO:0045727 | positive regulation of translation | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 4.68e-02 | 1.00e+00 | 4.386 | 1 | 7 | 46 |
GO:0043406 | positive regulation of MAP kinase activity | 4.68e-02 | 1.00e+00 | 4.386 | 1 | 4 | 46 |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 4.78e-02 | 1.00e+00 | 4.355 | 1 | 5 | 47 |
GO:0003723 | RNA binding | 4.80e-02 | 1.00e+00 | 2.491 | 2 | 20 | 342 |
GO:0003743 | translation initiation factor activity | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 8 | 49 |
GO:0003684 | damaged DNA binding | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 7 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 3 | 50 |
GO:0003725 | double-stranded RNA binding | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 5 | 53 |
GO:0005925 | focal adhesion | 5.42e-02 | 1.00e+00 | 2.393 | 2 | 19 | 366 |
GO:0045216 | cell-cell junction organization | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 3 | 54 |
GO:0006968 | cellular defense response | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 1 | 54 |
GO:0050679 | positive regulation of epithelial cell proliferation | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 1 | 54 |
GO:0007202 | activation of phospholipase C activity | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 3 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 3 | 55 |
GO:0008565 | protein transporter activity | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 5 | 56 |
GO:0000723 | telomere maintenance | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 6 | 56 |
GO:0005643 | nuclear pore | 5.77e-02 | 1.00e+00 | 4.076 | 1 | 4 | 57 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 6.16e-02 | 1.00e+00 | 3.978 | 1 | 2 | 61 |
GO:0006302 | double-strand break repair | 6.26e-02 | 1.00e+00 | 3.955 | 1 | 4 | 62 |
GO:0042060 | wound healing | 6.46e-02 | 1.00e+00 | 3.909 | 1 | 2 | 64 |
GO:0006289 | nucleotide-excision repair | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 11 | 68 |
GO:0003697 | single-stranded DNA binding | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 5 | 68 |
GO:0034329 | cell junction assembly | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 1 | 68 |
GO:0030307 | positive regulation of cell growth | 6.94e-02 | 1.00e+00 | 3.801 | 1 | 3 | 69 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.53e-02 | 1.00e+00 | 3.680 | 1 | 2 | 75 |
GO:0008584 | male gonad development | 7.53e-02 | 1.00e+00 | 3.680 | 1 | 3 | 75 |
GO:0019083 | viral transcription | 8.10e-02 | 1.00e+00 | 3.569 | 1 | 10 | 81 |
GO:0004713 | protein tyrosine kinase activity | 8.20e-02 | 1.00e+00 | 3.552 | 1 | 5 | 82 |
GO:0032321 | positive regulation of Rho GTPase activity | 8.20e-02 | 1.00e+00 | 3.552 | 1 | 1 | 82 |
GO:0006898 | receptor-mediated endocytosis | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 3 | 84 |
GO:0050852 | T cell receptor signaling pathway | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 4 | 85 |
GO:0047485 | protein N-terminus binding | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 5 | 86 |
GO:0006415 | translational termination | 8.68e-02 | 1.00e+00 | 3.466 | 1 | 10 | 87 |
GO:0016605 | PML body | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 3 | 88 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 8.97e-02 | 1.00e+00 | 3.417 | 1 | 7 | 90 |
GO:0042470 | melanosome | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 9.25e-02 | 1.00e+00 | 3.370 | 1 | 13 | 93 |
GO:0004888 | transmembrane signaling receptor activity | 9.44e-02 | 1.00e+00 | 3.339 | 1 | 1 | 95 |
GO:0043235 | receptor complex | 9.82e-02 | 1.00e+00 | 3.280 | 1 | 2 | 99 |
GO:0031410 | cytoplasmic vesicle | 1.02e-01 | 1.00e+00 | 3.223 | 1 | 1 | 103 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 10 | 104 |
GO:0001934 | positive regulation of protein phosphorylation | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 6 | 104 |
GO:0014069 | postsynaptic density | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 4 | 105 |
GO:0072562 | blood microparticle | 1.09e-01 | 1.00e+00 | 3.115 | 1 | 3 | 111 |
GO:0015630 | microtubule cytoskeleton | 1.09e-01 | 1.00e+00 | 3.128 | 1 | 4 | 110 |
GO:0030529 | ribonucleoprotein complex | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 8 | 112 |
GO:0005819 | spindle | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 7 | 112 |
GO:0005635 | nuclear envelope | 1.11e-01 | 1.00e+00 | 3.089 | 1 | 6 | 113 |
GO:0048015 | phosphatidylinositol-mediated signaling | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 7 | 114 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 11 | 114 |
GO:0044237 | cellular metabolic process | 1.15e-01 | 1.00e+00 | 3.039 | 1 | 5 | 117 |
GO:0046983 | protein dimerization activity | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 2 | 118 |
GO:0006325 | chromatin organization | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 9 | 121 |
GO:0009615 | response to virus | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 5 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.26e-01 | 1.00e+00 | 2.898 | 1 | 9 | 129 |
GO:0031982 | vesicle | 1.28e-01 | 1.00e+00 | 2.876 | 1 | 9 | 131 |
GO:0016323 | basolateral plasma membrane | 1.32e-01 | 1.00e+00 | 2.832 | 1 | 4 | 135 |
GO:0003735 | structural constituent of ribosome | 1.33e-01 | 1.00e+00 | 2.811 | 1 | 10 | 137 |
GO:0005911 | cell-cell junction | 1.33e-01 | 1.00e+00 | 2.822 | 1 | 4 | 136 |
GO:0007507 | heart development | 1.35e-01 | 1.00e+00 | 2.790 | 1 | 7 | 139 |
GO:0006457 | protein folding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 7 | 143 |
GO:0007166 | cell surface receptor signaling pathway | 1.43e-01 | 1.00e+00 | 2.710 | 1 | 3 | 147 |
GO:0005198 | structural molecule activity | 1.45e-01 | 1.00e+00 | 2.680 | 1 | 5 | 150 |
GO:0010008 | endosome membrane | 1.46e-01 | 1.00e+00 | 2.671 | 1 | 7 | 151 |
GO:0005524 | ATP binding | 1.47e-01 | 1.00e+00 | 1.152 | 3 | 60 | 1298 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.51e-01 | 1.00e+00 | 2.624 | 1 | 9 | 156 |
GO:0046777 | protein autophosphorylation | 1.52e-01 | 1.00e+00 | 2.605 | 1 | 7 | 158 |
GO:0008022 | protein C-terminus binding | 1.55e-01 | 1.00e+00 | 2.578 | 1 | 5 | 161 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.59e-01 | 1.00e+00 | 2.543 | 1 | 7 | 165 |
GO:0030424 | axon | 1.59e-01 | 1.00e+00 | 2.534 | 1 | 4 | 166 |
GO:0031965 | nuclear membrane | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 3 | 168 |
GO:0006886 | intracellular protein transport | 1.64e-01 | 1.00e+00 | 2.491 | 1 | 5 | 171 |
GO:0019904 | protein domain specific binding | 1.71e-01 | 1.00e+00 | 2.425 | 1 | 6 | 179 |
GO:0032403 | protein complex binding | 1.74e-01 | 1.00e+00 | 2.393 | 1 | 10 | 183 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.80e-01 | 1.00e+00 | 2.347 | 1 | 12 | 189 |
GO:0016324 | apical plasma membrane | 1.88e-01 | 1.00e+00 | 2.273 | 1 | 5 | 199 |
GO:0001701 | in utero embryonic development | 1.90e-01 | 1.00e+00 | 2.258 | 1 | 8 | 201 |
GO:0019221 | cytokine-mediated signaling pathway | 2.07e-01 | 1.00e+00 | 2.121 | 1 | 9 | 221 |
GO:0007067 | mitotic nuclear division | 2.12e-01 | 1.00e+00 | 2.083 | 1 | 14 | 227 |
GO:0005759 | mitochondrial matrix | 2.13e-01 | 1.00e+00 | 2.076 | 1 | 14 | 228 |
GO:0004842 | ubiquitin-protein transferase activity | 2.35e-01 | 1.00e+00 | 1.915 | 1 | 6 | 255 |
GO:0007165 | signal transduction | 2.43e-01 | 1.00e+00 | 1.084 | 2 | 24 | 907 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.46e-01 | 1.00e+00 | 1.838 | 1 | 15 | 269 |
GO:0005856 | cytoskeleton | 2.64e-01 | 1.00e+00 | 1.724 | 1 | 12 | 291 |
GO:0016567 | protein ubiquitination | 2.67e-01 | 1.00e+00 | 1.705 | 1 | 5 | 295 |
GO:0035556 | intracellular signal transduction | 2.73e-01 | 1.00e+00 | 1.666 | 1 | 9 | 303 |
GO:0008270 | zinc ion binding | 2.78e-01 | 1.00e+00 | 0.948 | 2 | 12 | 997 |
GO:0005813 | centrosome | 2.90e-01 | 1.00e+00 | 1.560 | 1 | 14 | 326 |
GO:0008283 | cell proliferation | 2.92e-01 | 1.00e+00 | 1.552 | 1 | 14 | 328 |
GO:0007155 | cell adhesion | 3.22e-01 | 1.00e+00 | 1.382 | 1 | 6 | 369 |
GO:0046982 | protein heterodimerization activity | 3.30e-01 | 1.00e+00 | 1.339 | 1 | 13 | 380 |
GO:0005737 | cytoplasm | 3.51e-01 | 1.00e+00 | 0.352 | 5 | 110 | 3767 |
GO:0007596 | blood coagulation | 3.82e-01 | 1.00e+00 | 1.079 | 1 | 18 | 455 |
GO:0006468 | protein phosphorylation | 3.85e-01 | 1.00e+00 | 1.064 | 1 | 18 | 460 |
GO:0046872 | metal ion binding | 4.00e-01 | 1.00e+00 | 0.557 | 2 | 25 | 1307 |
GO:0042802 | identical protein binding | 4.01e-01 | 1.00e+00 | 0.990 | 1 | 20 | 484 |
GO:0048471 | perinuclear region of cytoplasm | 4.12e-01 | 1.00e+00 | 0.938 | 1 | 13 | 502 |
GO:0005886 | plasma membrane | 5.19e-01 | 1.00e+00 | 0.160 | 3 | 45 | 2582 |
GO:0005615 | extracellular space | 6.43e-01 | 1.00e+00 | 0.007 | 1 | 17 | 957 |
GO:0005739 | mitochondrion | 6.59e-01 | 1.00e+00 | -0.054 | 1 | 28 | 998 |
GO:0006351 | transcription, DNA-templated | 7.95e-01 | 1.00e+00 | -0.589 | 1 | 31 | 1446 |
GO:0016021 | integral component of membrane | 8.91e-01 | 1.00e+00 | -1.044 | 1 | 27 | 1982 |