int-snw-2064

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.950 4.36e-16 1.79e-03 3.17e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-2064 subnetwork

Genes (15)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RPA2 6118 981.2501.15169Yes-
ACO2 50 501.0001.076191Yes-
EIF2S2 8894 271.0751.13881Yes-
RBX1 9978 971.1851.151139Yes-
PSMA2 5683 601.0931.10689Yes-
PSMD3 5709 570.9861.106146Yes-
CLTC 1213 350.8841.138247Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
[ ERBB2 ] 2064 10.0040.950156Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
RPSA 3921 1561.3271.151152Yes-
KPNB1 3837 60.6131.017296Yes-
ITK 3702 20.6020.95039Yes-

Interactions (31)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
CLTC 1213 KPNB1 3837 pp -- int.Intact: MI:0914(association)
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ERBB2 2064 ITK 3702 pp -- int.I2D: JonesErbB1, MINT;
int.Mint: MI:0407(direct interaction)
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
CLTC 1213 ERBB2 2064 pp -- int.Intact: MI:0914(association)
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
KPNB1 3837 PSMA2 5683 pp -- int.I2D: Krogan_NonCore, YeastLow
ACTB 60 KPNB1 3837 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
ACO2 50 KPNB1 3837 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 ERBB2 2064 pp -- int.Intact: MI:0915(physical association), MI:0403(colocalization), MI:0914(association)
KPNB1 3837 PSMD11 5717 pp -- int.I2D: Krogan_NonCore
KPNB1 3837 PSMA1 5682 pp -- int.I2D: YeastLow
ERBB2 2064 KPNB1 3837 pp -- int.Intact: MI:0915(physical association), MI:0914(association), MI:0403(colocalization)
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (278)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006521regulation of cellular amino acid metabolic process1.19e-091.72e-056.58751750
GO:0000502proteasome complex2.57e-093.70e-056.37351758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest4.26e-096.14e-056.23151964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.61e-096.65e-056.20952265
GO:0000082G1/S transition of mitotic cell cycle5.09e-097.35e-055.275632149
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.73e-099.71e-056.10252270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent7.78e-091.12e-046.06152072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.94e-091.29e-046.02252274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I9.58e-091.38e-046.00252075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.25e-081.80e-045.92752379
GO:0016032viral process1.72e-082.47e-043.848855534
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.70e-083.90e-045.70852192
GO:0016071mRNA metabolic process5.69e-088.21e-044.693631223
GO:0000209protein polyubiquitination8.69e-081.25e-035.373520116
GO:0016070RNA metabolic process1.04e-071.51e-034.546632247
GO:0005829cytosol1.91e-072.76e-032.209121322496
GO:0005654nucleoplasm2.41e-073.48e-033.0009761082
GO:0042981regulation of apoptotic process3.14e-074.53e-035.002524150
GO:0034641cellular nitrogen compound metabolic process6.03e-078.69e-034.813520171
GO:0005839proteasome core complex7.36e-071.06e-027.3243818
GO:0004298threonine-type endopeptidase activity8.73e-071.26e-027.2463819
GO:0000278mitotic cell cycle1.55e-062.24e-023.883648391
GO:0010467gene expression2.08e-063.00e-023.331759669
GO:0006915apoptotic process1.18e-051.70e-013.378633555
GO:0019773proteasome core complex, alpha-subunit complex2.82e-054.06e-017.909248
GO:0043066negative regulation of apoptotic process5.05e-057.28e-013.503531424
GO:0005838proteasome regulatory particle6.62e-059.55e-017.3242712
GO:0044281small molecule metabolic process1.02e-041.00e+002.4757581211
GO:0022624proteasome accessory complex1.36e-041.00e+006.8222817
GO:0070062extracellular vesicular exosome1.84e-041.00e+001.85091042400
GO:0005515protein binding4.61e-041.00e+001.053131846024
GO:0001042RNA polymerase I core binding1.04e-031.00e+009.909111
GO:0019903protein phosphatase binding1.84e-031.00e+004.9552462
GO:00515383 iron, 4 sulfur cluster binding2.08e-031.00e+008.909112
GO:0002176male germ cell proliferation2.08e-031.00e+008.909112
GO:0003994aconitate hydratase activity2.08e-031.00e+008.909112
GO:0006407rRNA export from nucleus2.08e-031.00e+008.909112
GO:0032633interleukin-4 production2.08e-031.00e+008.909112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.08e-031.00e+008.909112
GO:0005055laminin receptor activity2.08e-031.00e+008.909112
GO:0001865NK T cell differentiation2.08e-031.00e+008.909112
GO:0005850eukaryotic translation initiation factor 2 complex3.12e-031.00e+008.324113
GO:1900126negative regulation of hyaluronan biosynthetic process3.12e-031.00e+008.324123
GO:0071439clathrin complex3.12e-031.00e+008.324123
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.15e-031.00e+007.909114
GO:003068690S preribosome4.15e-031.00e+007.909114
GO:0032051clathrin light chain binding4.15e-031.00e+007.909114
GO:0019788NEDD8 ligase activity4.15e-031.00e+007.909114
GO:0043125ErbB-3 class receptor binding4.15e-031.00e+007.909114
GO:0031467Cul7-RING ubiquitin ligase complex4.15e-031.00e+007.909114
GO:0033088negative regulation of immature T cell proliferation in thymus4.15e-031.00e+007.909114
GO:0006610ribosomal protein import into nucleus4.15e-031.00e+007.909114
GO:1903077negative regulation of protein localization to plasma membrane4.15e-031.00e+007.909114
GO:0071782endoplasmic reticulum tubular network4.15e-031.00e+007.909114
GO:0016020membrane4.89e-031.00e+001.7796901681
GO:0031465Cul4B-RING E3 ubiquitin ligase complex5.19e-031.00e+007.587135
GO:2000001regulation of DNA damage checkpoint5.19e-031.00e+007.587115
GO:0031461cullin-RING ubiquitin ligase complex5.19e-031.00e+007.587115
GO:0043248proteasome assembly5.19e-031.00e+007.587115
GO:0006102isocitrate metabolic process5.19e-031.00e+007.587115
GO:0030891VCB complex5.19e-031.00e+007.587125
GO:0000730DNA recombinase assembly5.19e-031.00e+007.587115
GO:0005634nucleus5.55e-031.00e+001.077101364559
GO:0019058viral life cycle6.18e-031.00e+004.064213115
GO:0030130clathrin coat of trans-Golgi network vesicle6.22e-031.00e+007.324136
GO:0006101citrate metabolic process6.22e-031.00e+007.324116
GO:0030118clathrin coat6.22e-031.00e+007.324126
GO:0031466Cul5-RING ubiquitin ligase complex6.22e-031.00e+007.324116
GO:0030957Tat protein binding6.22e-031.00e+007.324136
GO:0045943positive regulation of transcription from RNA polymerase I promoter6.22e-031.00e+007.324116
GO:0000028ribosomal small subunit assembly7.26e-031.00e+007.102117
GO:0031462Cul2-RING ubiquitin ligase complex7.26e-031.00e+007.102127
GO:0030132clathrin coat of coated pit7.26e-031.00e+007.102127
GO:0006413translational initiation7.96e-031.00e+003.876217131
GO:0018108peptidyl-tyrosine phosphorylation8.07e-031.00e+003.86527132
GO:0031464Cul4A-RING E3 ubiquitin ligase complex8.29e-031.00e+006.909128
GO:0070688MLL5-L complex8.29e-031.00e+006.909118
GO:0045116protein neddylation8.29e-031.00e+006.909128
GO:0008139nuclear localization sequence binding9.32e-031.00e+006.739139
GO:0004716receptor signaling protein tyrosine kinase activity9.32e-031.00e+006.739119
GO:0032609interferon-gamma production9.32e-031.00e+006.739119
GO:0007167enzyme linked receptor protein signaling pathway9.32e-031.00e+006.739119
GO:0061024membrane organization9.67e-031.00e+003.72927145
GO:0010569regulation of double-strand break repair via homologous recombination1.04e-021.00e+006.5871110
GO:0045945positive regulation of transcription from RNA polymerase III promoter1.14e-021.00e+006.4501111
GO:0031571mitotic G1 DNA damage checkpoint1.14e-021.00e+006.4501411
GO:0044267cellular protein metabolic process1.20e-021.00e+002.605329474
GO:0032886regulation of microtubule-based process1.24e-021.00e+006.3241312
GO:0038095Fc-epsilon receptor signaling pathway1.28e-021.00e+003.517212168
GO:0005662DNA replication factor A complex1.34e-021.00e+006.2091113
GO:0030234enzyme regulator activity1.34e-021.00e+006.2091313
GO:0031625ubiquitin protein ligase binding1.43e-021.00e+003.433214178
GO:0035267NuA4 histone acetyltransferase complex1.45e-021.00e+006.1021414
GO:0006607NLS-bearing protein import into nucleus1.45e-021.00e+006.1021314
GO:0042176regulation of protein catabolic process1.65e-021.00e+005.9091316
GO:0050998nitric-oxide synthase binding1.65e-021.00e+005.9091116
GO:0075733intracellular transport of virus1.75e-021.00e+005.8221317
GO:0006309apoptotic DNA fragmentation1.75e-021.00e+005.8221117
GO:0070372regulation of ERK1 and ERK2 cascade1.75e-021.00e+005.8221117
GO:0035861site of double-strand break1.86e-021.00e+005.7391118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.96e-021.00e+005.6611119
GO:0048863stem cell differentiation1.96e-021.00e+005.6611119
GO:0008045motor neuron axon guidance1.96e-021.00e+005.6611119
GO:0044822poly(A) RNA binding2.03e-021.00e+001.8654491056
GO:0006298mismatch repair2.06e-021.00e+005.5871320
GO:0005730nucleolus2.14e-021.00e+001.5515691641
GO:0014065phosphatidylinositol 3-kinase signaling2.16e-021.00e+005.5171221
GO:0000718nucleotide-excision repair, DNA damage removal2.16e-021.00e+005.5171421
GO:0032201telomere maintenance via semi-conservative replication2.16e-021.00e+005.5171521
GO:0045087innate immune response2.20e-021.00e+002.275324596
GO:0006297nucleotide-excision repair, DNA gap filling2.26e-021.00e+005.4501322
GO:0030863cortical cytoskeleton2.26e-021.00e+005.4501122
GO:0036464cytoplasmic ribonucleoprotein granule2.26e-021.00e+005.4501422
GO:0006412translation2.32e-021.00e+003.064220230
GO:0031463Cul3-RING ubiquitin ligase complex2.37e-021.00e+005.3861323
GO:0043236laminin binding2.37e-021.00e+005.3861123
GO:0006513protein monoubiquitination2.37e-021.00e+005.3861123
GO:0048709oligodendrocyte differentiation2.37e-021.00e+005.3861123
GO:0043044ATP-dependent chromatin remodeling2.37e-021.00e+005.3861423
GO:0005844polysome2.37e-021.00e+005.3861423
GO:0008135translation factor activity, nucleic acid binding2.47e-021.00e+005.3241724
GO:0045765regulation of angiogenesis2.47e-021.00e+005.3241124
GO:0000060protein import into nucleus, translocation2.47e-021.00e+005.3241524
GO:0007422peripheral nervous system development2.57e-021.00e+005.2651125
GO:0001816cytokine production2.57e-021.00e+005.2651325
GO:0000722telomere maintenance via recombination2.57e-021.00e+005.2651525
GO:0008536Ran GTPase binding2.57e-021.00e+005.2651125
GO:0019838growth factor binding2.57e-021.00e+005.2651125
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.67e-021.00e+005.2091326
GO:0043022ribosome binding2.77e-021.00e+005.1541327
GO:0031492nucleosomal DNA binding2.77e-021.00e+005.1541427
GO:0023014signal transduction by phosphorylation2.87e-021.00e+005.1021128
GO:0006099tricarboxylic acid cycle2.87e-021.00e+005.1021428
GO:0002250adaptive immune response2.87e-021.00e+005.1021128
GO:0030669clathrin-coated endocytic vesicle membrane2.87e-021.00e+005.1021428
GO:0019894kinesin binding2.87e-021.00e+005.1021128
GO:0006281DNA repair2.93e-021.00e+002.881218261
GO:0019005SCF ubiquitin ligase complex2.98e-021.00e+005.0511129
GO:0006606protein import into nucleus3.08e-021.00e+005.0021230
GO:0033572transferrin transport3.08e-021.00e+005.0021530
GO:0006271DNA strand elongation involved in DNA replication3.08e-021.00e+005.0021730
GO:0004714transmembrane receptor protein tyrosine kinase activity3.08e-021.00e+005.0021230
GO:0031623receptor internalization3.18e-021.00e+004.9551231
GO:0019899enzyme binding3.27e-021.00e+002.795212277
GO:0007528neuromuscular junction development3.28e-021.00e+004.9091132
GO:0032588trans-Golgi network membrane3.48e-021.00e+004.8221234
GO:0001895retina homeostasis3.48e-021.00e+004.8221134
GO:0042552myelination3.58e-021.00e+004.7801135
GO:00515394 iron, 4 sulfur cluster binding3.58e-021.00e+004.7801335
GO:0043234protein complex3.67e-021.00e+002.705218295
GO:0034332adherens junction organization3.68e-021.00e+004.7391136
GO:0051084'de novo' posttranslational protein folding3.78e-021.00e+004.7001437
GO:0006284base-excision repair3.78e-021.00e+004.7001337
GO:0070527platelet aggregation3.88e-021.00e+004.6611238
GO:0000781chromosome, telomeric region3.98e-021.00e+004.6241339
GO:0022627cytosolic small ribosomal subunit3.98e-021.00e+004.6241439
GO:0045785positive regulation of cell adhesion4.08e-021.00e+004.5871440
GO:0019901protein kinase binding4.19e-021.00e+002.601221317
GO:0007411axon guidance4.24e-021.00e+002.592213319
GO:0042110T cell activation4.28e-021.00e+004.5171342
GO:0030136clathrin-coated vesicle4.28e-021.00e+004.5171442
GO:0004715non-membrane spanning protein tyrosine kinase activity4.28e-021.00e+004.5171442
GO:0006892post-Golgi vesicle-mediated transport4.38e-021.00e+004.4831343
GO:0021762substantia nigra development4.48e-021.00e+004.4501244
GO:0045727positive regulation of translation4.48e-021.00e+004.4501344
GO:0006283transcription-coupled nucleotide-excision repair4.68e-021.00e+004.3861746
GO:0043406positive regulation of MAP kinase activity4.68e-021.00e+004.3861446
GO:0006921cellular component disassembly involved in execution phase of apoptosis4.78e-021.00e+004.3551547
GO:0003723RNA binding4.80e-021.00e+002.491220342
GO:0003743translation initiation factor activity4.98e-021.00e+004.2941849
GO:0003684damaged DNA binding4.98e-021.00e+004.2941749
GO:0006091generation of precursor metabolites and energy5.08e-021.00e+004.2651350
GO:0003725double-stranded RNA binding5.28e-021.00e+004.2091552
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.38e-021.00e+004.1811553
GO:0005925focal adhesion5.42e-021.00e+002.393219366
GO:0045216cell-cell junction organization5.47e-021.00e+004.1541254
GO:0000932cytoplasmic mRNA processing body5.47e-021.00e+004.1541354
GO:0006968cellular defense response5.47e-021.00e+004.1541154
GO:0050679positive regulation of epithelial cell proliferation5.47e-021.00e+004.1541154
GO:0007202activation of phospholipase C activity5.57e-021.00e+004.1281355
GO:0000724double-strand break repair via homologous recombination5.57e-021.00e+004.1281355
GO:0008565protein transporter activity5.67e-021.00e+004.1021556
GO:0000723telomere maintenance5.67e-021.00e+004.1021656
GO:0005643nuclear pore5.77e-021.00e+004.0761457
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway6.16e-021.00e+003.9781261
GO:0006302double-strand break repair6.26e-021.00e+003.9551462
GO:0042060wound healing6.46e-021.00e+003.9091264
GO:0006289nucleotide-excision repair6.85e-021.00e+003.82211168
GO:0003697single-stranded DNA binding6.85e-021.00e+003.8221568
GO:0034329cell junction assembly6.85e-021.00e+003.8221168
GO:0030307positive regulation of cell growth6.94e-021.00e+003.8011369
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis7.43e-021.00e+003.7001674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process7.53e-021.00e+003.6801275
GO:0008584male gonad development7.53e-021.00e+003.6801375
GO:0019083viral transcription8.10e-021.00e+003.56911081
GO:0004713protein tyrosine kinase activity8.20e-021.00e+003.5521582
GO:0032321positive regulation of Rho GTPase activity8.20e-021.00e+003.5521182
GO:0006898receptor-mediated endocytosis8.39e-021.00e+003.5171384
GO:0050852T cell receptor signaling pathway8.49e-021.00e+003.5001485
GO:0047485protein N-terminus binding8.58e-021.00e+003.4831586
GO:0006415translational termination8.68e-021.00e+003.46611087
GO:0016605PML body8.78e-021.00e+003.4501388
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II8.97e-021.00e+003.4171790
GO:0042470melanosome9.06e-021.00e+003.4011991
GO:0006928cellular component movement9.06e-021.00e+003.4011791
GO:0005200structural constituent of cytoskeleton9.06e-021.00e+003.4011891
GO:0001649osteoblast differentiation9.16e-021.00e+003.3861692
GO:0071456cellular response to hypoxia9.16e-021.00e+003.3861692
GO:0006414translational elongation9.25e-021.00e+003.37011393
GO:0004888transmembrane signaling receptor activity9.44e-021.00e+003.3391195
GO:0043235receptor complex9.82e-021.00e+003.2801299
GO:0031410cytoplasmic vesicle1.02e-011.00e+003.22311103
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.03e-011.00e+003.209110104
GO:0001934positive regulation of protein phosphorylation1.03e-011.00e+003.20916104
GO:0014069postsynaptic density1.04e-011.00e+003.19513105
GO:0005506iron ion binding1.04e-011.00e+003.19514105
GO:0072562blood microparticle1.09e-011.00e+003.11513111
GO:0015630microtubule cytoskeleton1.09e-011.00e+003.12814110
GO:0030529ribonucleoprotein complex1.10e-011.00e+003.10218112
GO:0005819spindle1.10e-011.00e+003.10217112
GO:0005635nuclear envelope1.11e-011.00e+003.08916113
GO:0048015phosphatidylinositol-mediated signaling1.12e-011.00e+003.07617114
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.12e-011.00e+003.076111114
GO:0044237cellular metabolic process1.15e-011.00e+003.03915117
GO:0046983protein dimerization activity1.16e-011.00e+003.02712118
GO:0006325chromatin organization1.16e-011.00e+003.02715118
GO:0007219Notch signaling pathway1.18e-011.00e+003.00215120
GO:0006260DNA replication1.19e-011.00e+002.99019121
GO:0009615response to virus1.23e-011.00e+002.93215126
GO:0006511ubiquitin-dependent protein catabolic process1.23e-011.00e+002.93215126
GO:0000790nuclear chromatin1.26e-011.00e+002.89819129
GO:0031982vesicle1.28e-011.00e+002.87619131
GO:0016323basolateral plasma membrane1.32e-011.00e+002.83214135
GO:0003735structural constituent of ribosome1.33e-011.00e+002.811110137
GO:0005911cell-cell junction1.33e-011.00e+002.82214136
GO:0007507heart development1.35e-011.00e+002.79017139
GO:0006457protein folding1.39e-011.00e+002.74917143
GO:0007166cell surface receptor signaling pathway1.43e-011.00e+002.71013147
GO:0005198structural molecule activity1.45e-011.00e+002.68015150
GO:0010008endosome membrane1.46e-011.00e+002.67117151
GO:0005524ATP binding1.47e-011.00e+001.1523601298
GO:0008543fibroblast growth factor receptor signaling pathway1.51e-011.00e+002.62419156
GO:0046777protein autophosphorylation1.52e-011.00e+002.60517158
GO:0008022protein C-terminus binding1.55e-011.00e+002.57815161
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.59e-011.00e+002.54317165
GO:0030424axon1.59e-011.00e+002.53414166
GO:0031965nuclear membrane1.61e-011.00e+002.51713168
GO:0006886intracellular protein transport1.64e-011.00e+002.49115171
GO:0019904protein domain specific binding1.71e-011.00e+002.42516179
GO:0032403protein complex binding1.74e-011.00e+002.393110183
GO:0007173epidermal growth factor receptor signaling pathway1.80e-011.00e+002.347112189
GO:0016324apical plasma membrane1.88e-011.00e+002.27315199
GO:0001701in utero embryonic development1.90e-011.00e+002.25818201
GO:0019221cytokine-mediated signaling pathway2.07e-011.00e+002.12119221
GO:0007067mitotic nuclear division2.12e-011.00e+002.083114227
GO:0005759mitochondrial matrix2.13e-011.00e+002.076114228
GO:0004842ubiquitin-protein transferase activity2.35e-011.00e+001.91516255
GO:0007165signal transduction2.43e-011.00e+001.084224907
GO:0048011neurotrophin TRK receptor signaling pathway2.46e-011.00e+001.838115269
GO:0005856cytoskeleton2.64e-011.00e+001.724112291
GO:0016567protein ubiquitination2.67e-011.00e+001.70515295
GO:0035556intracellular signal transduction2.73e-011.00e+001.66619303
GO:0008270zinc ion binding2.78e-011.00e+000.948212997
GO:0005813centrosome2.90e-011.00e+001.560114326
GO:0008283cell proliferation2.92e-011.00e+001.552114328
GO:0007155cell adhesion3.22e-011.00e+001.38216369
GO:0046982protein heterodimerization activity3.30e-011.00e+001.339113380
GO:0005737cytoplasm3.51e-011.00e+000.35251103767
GO:0007596blood coagulation3.82e-011.00e+001.079118455
GO:0006468protein phosphorylation3.85e-011.00e+001.064118460
GO:0046872metal ion binding4.00e-011.00e+000.5572251307
GO:0042802identical protein binding4.01e-011.00e+000.990120484
GO:0048471perinuclear region of cytoplasm4.12e-011.00e+000.938113502
GO:0005886plasma membrane5.19e-011.00e+000.1603452582
GO:0005615extracellular space6.43e-011.00e+000.007117957
GO:0005739mitochondrion6.59e-011.00e+00-0.054128998
GO:0006351transcription, DNA-templated7.95e-011.00e+00-0.5891311446
GO:0016021integral component of membrane8.91e-011.00e+00-1.0441271982