reg-snw-9631

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.312 7.43e-08 2.27e-02 1.81e-02
chia-screen-data-Fav-reg-snw-9631 subnetwork

Genes (20)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
CENPA 1058 27-2.1852.393205TFYes-
TMEM68 137695 6-1.5652.31297TF--
FOXM1 2305 9-1.6692.412210TF--
PHB 5245 82-2.7432.68936-YesYes
[ NUP155 ] 9631 1-1.3092.31232---
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
EXO1 9156 3-1.5212.312159TF--
EIF2S2 8894 40-2.9992.45922-YesYes
FBXL6 26233 28-2.2532.68922-Yes-
NCBP1 4686 41-2.5102.45944-YesYes
SUV39H2 79723 27-2.3072.41021-YesYes
SHFM1 7979 7-2.3662.3893-Yes-
TRAIP 10293 13-2.5462.45430TFYes-
FTSJ1 24140 43-2.4632.68935-YesYes
CCT7 10574 40-2.3352.45938-Yes-
CPSF3 51692 43-2.6862.50331-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes

Interactions (31)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FOXM1 2305 EXO1 9156 pd <> reg.ITFP.txt: no annot
FOXM1 2305 NUP155 9631 pd > reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
NUP155 9631 TMEM68 137695 pd < reg.ITFP.txt: no annot
CENPA 1058 FBXL6 26233 pd > reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
FOXM1 2305 SHFM1 7979 pd > reg.ITFP.txt: no annot
CENPA 1058 FOXM1 2305 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
EXO1 9156 NUP155 9631 pd > reg.ITFP.txt: no annot
CENPA 1058 EXO1 9156 pd <> reg.ITFP.txt: no annot
EXO1 9156 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
CENPA 1058 NUP155 9631 pd > reg.ITFP.txt: no annot
CENPA 1058 SUV39H2 79723 pd > reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
EXO1 9156 SUV39H2 79723 pd > reg.ITFP.txt: no annot
VARS 7407 NUP155 9631 pd > reg.ITFP.txt: no annot
CPSF3 51692 TMEM68 137695 pd < reg.ITFP.txt: no annot
FOXM1 2305 TRAIP 10293 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
NUP155 9631 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
FOXM1 2305 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
TRAIP 10293 CPSF3 51692 pd > reg.ITFP.txt: no annot
SUV39H2 79723 TMEM68 137695 pd < reg.ITFP.txt: no annot
CENPA 1058 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot

Related GO terms (211)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:00084095'-3' exonuclease activity8.32e-058.12e-017.124227
GO:0006406mRNA export from nucleus9.22e-059.01e-015.0573744
GO:0006379mRNA cleavage1.42e-041.00e+006.762229
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic8.18e-041.00e+005.5392221
GO:0004832valine-tRNA ligase activity2.05e-031.00e+008.931111
GO:00353125'-3' exodeoxyribonuclease activity2.05e-031.00e+008.931111
GO:0002128tRNA nucleoside ribose methylation2.05e-031.00e+008.931111
GO:0051908double-stranded DNA 5'-3' exodeoxyribonuclease activity2.05e-031.00e+008.931111
GO:0008175tRNA methyltransferase activity2.05e-031.00e+008.931111
GO:0000939condensed chromosome inner kinetochore2.05e-031.00e+008.931111
GO:0006438valyl-tRNA aminoacylation2.05e-031.00e+008.931111
GO:0048256flap endonuclease activity2.05e-031.00e+008.931111
GO:0031124mRNA 3'-end processing2.28e-031.00e+004.8022435
GO:0006369termination of RNA polymerase II transcription2.68e-031.00e+004.6842538
GO:0000775chromosome, centromeric region3.12e-031.00e+004.5742641
GO:0045145single-stranded DNA 5'-3' exodeoxyribonuclease activity4.09e-031.00e+007.931112
GO:0048742regulation of skeletal muscle fiber development4.09e-031.00e+007.931112
GO:0005846nuclear cap binding complex4.09e-031.00e+007.931112
GO:0002176male germ cell proliferation4.09e-031.00e+007.931112
GO:2000781positive regulation of double-strand break repair4.09e-031.00e+007.931112
GO:0004842ubiquitin-protein transferase activity5.49e-031.00e+003.033317179
GO:0005850eukaryotic translation initiation factor 2 complex6.13e-031.00e+007.347123
GO:0036123histone H3-K9 dimethylation6.13e-031.00e+007.347113
GO:0000778condensed nuclear chromosome kinetochore6.13e-031.00e+007.347123
GO:0071459protein localization to chromosome, centromeric region6.13e-031.00e+007.347113
GO:0005654nucleoplasm6.62e-031.00e+001.742668876
GO:0006281DNA repair7.77e-031.00e+002.851324203
GO:0045292mRNA cis splicing, via spliceosome8.17e-031.00e+006.931114
GO:0031442positive regulation of mRNA 3'-end processing8.17e-031.00e+006.931114
GO:0006290pyrimidine dimer repair8.17e-031.00e+006.931124
GO:0036124histone H3-K9 trimethylation8.17e-031.00e+006.931124
GO:0006333chromatin assembly or disassembly8.17e-031.00e+006.931114
GO:0071156regulation of cell cycle arrest8.17e-031.00e+006.931124
GO:0004521endoribonuclease activity1.02e-021.00e+006.610115
GO:0006398histone mRNA 3'-end processing1.02e-021.00e+006.610115
GO:0090344negative regulation of cell aging1.02e-021.00e+006.610115
GO:0086014atrial cardiac muscle cell action potential1.02e-021.00e+006.610115
GO:0006282regulation of DNA repair1.02e-021.00e+006.610125
GO:0032873negative regulation of stress-activated MAPK cascade1.02e-021.00e+006.610115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.02e-021.00e+006.610115
GO:0002161aminoacyl-tRNA editing activity1.02e-021.00e+006.610115
GO:0004523RNA-DNA hybrid ribonuclease activity1.02e-021.00e+006.610115
GO:0030529ribonucleoprotein complex1.20e-021.00e+003.5742582
GO:0050847progesterone receptor signaling pathway1.22e-021.00e+006.347126
GO:0002181cytoplasmic translation1.22e-021.00e+006.347116
GO:0043566structure-specific DNA binding1.22e-021.00e+006.347116
GO:0042754negative regulation of circadian rhythm1.22e-021.00e+006.347126
GO:0046974histone methyltransferase activity (H3-K9 specific)1.22e-021.00e+006.347116
GO:0016446somatic hypermutation of immunoglobulin genes1.22e-021.00e+006.347116
GO:0002455humoral immune response mediated by circulating immunoglobulin1.22e-021.00e+006.347116
GO:0046578regulation of Ras protein signal transduction1.22e-021.00e+006.347116
GO:0003723RNA binding1.33e-021.00e+002.568322247
GO:0002199zona pellucida receptor complex1.43e-021.00e+006.124147
GO:0007140male meiosis1.43e-021.00e+006.124117
GO:0000731DNA synthesis involved in DNA repair1.43e-021.00e+006.124117
GO:0006301postreplication repair1.43e-021.00e+006.124127
GO:0000339RNA cap binding1.43e-021.00e+006.124117
GO:0000780condensed nuclear chromosome, centromeric region1.43e-021.00e+006.124117
GO:0005832chaperonin-containing T-complex1.43e-021.00e+006.124147
GO:0006998nuclear envelope organization1.43e-021.00e+006.124117
GO:0051382kinetochore assembly1.43e-021.00e+006.124127
GO:0005845mRNA cap binding complex1.63e-021.00e+005.931118
GO:0006450regulation of translational fidelity1.63e-021.00e+005.931118
GO:0010944negative regulation of transcription by competitive promoter binding1.63e-021.00e+005.931118
GO:0010388cullin deneddylation1.63e-021.00e+005.931148
GO:0017056structural constituent of nuclear pore1.63e-021.00e+005.931138
GO:0010225response to UV-C1.83e-021.00e+005.762129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.83e-021.00e+005.762129
GO:0071354cellular response to interleukin-61.83e-021.00e+005.762119
GO:0032039integrator complex1.83e-021.00e+005.762119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex1.83e-021.00e+005.762139
GO:0005095GTPase inhibitor activity2.03e-021.00e+005.6101110
GO:0010467gene expression2.14e-021.00e+001.868449535
GO:0060766negative regulation of androgen receptor signaling pathway2.23e-021.00e+005.4721411
GO:0008334histone mRNA metabolic process2.23e-021.00e+005.4721111
GO:0007049cell cycle2.27e-021.00e+003.08628115
GO:0000132establishment of mitotic spindle orientation2.43e-021.00e+005.3471212
GO:0004527exonuclease activity2.43e-021.00e+005.3471412
GO:0000278mitotic cell cycle2.50e-021.00e+002.222328314
GO:0045892negative regulation of transcription, DNA-templated2.57e-021.00e+002.208317317
GO:0045190isotype switching2.63e-021.00e+005.2311113
GO:2000377regulation of reactive oxygen species metabolic process2.63e-021.00e+005.2311113
GO:0000738DNA catabolic process, exonucleolytic2.63e-021.00e+005.2311113
GO:0000398mRNA splicing, via spliceosome2.78e-021.00e+002.931215128
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator2.83e-021.00e+005.1241114
GO:0016746transferase activity, transferring acyl groups2.83e-021.00e+005.1241214
GO:0016575histone deacetylation2.83e-021.00e+005.1241214
GO:0008135translation factor activity, nucleic acid binding3.03e-021.00e+005.0251415
GO:0000188inactivation of MAPK activity3.03e-021.00e+005.0251115
GO:0007339binding of sperm to zona pellucida3.03e-021.00e+005.0251415
GO:0006366transcription from RNA polymerase II promoter3.10e-021.00e+002.103323341
GO:0003887DNA-directed DNA polymerase activity3.23e-021.00e+004.9311216
GO:0005515protein binding3.38e-021.00e+000.622131984124
GO:0044212transcription regulatory region DNA binding3.41e-021.00e+002.772213143
GO:0006298mismatch repair3.43e-021.00e+004.8441117
GO:0031047gene silencing by RNA3.63e-021.00e+004.7621218
GO:0006378mRNA polyadenylation3.63e-021.00e+004.7621318
GO:0006913nucleocytoplasmic transport4.02e-021.00e+004.6101220
GO:0034080CENP-A containing nucleosome assembly4.02e-021.00e+004.6101220
GO:0051321meiotic cell cycle4.02e-021.00e+004.6101120
GO:0005720nuclear heterochromatin4.02e-021.00e+004.6101320
GO:0071897DNA biosynthetic process4.02e-021.00e+004.6101220
GO:0034660ncRNA metabolic process4.02e-021.00e+004.6101120
GO:0005739mitochondrion4.19e-021.00e+001.567432659
GO:0006606protein import into nucleus4.41e-021.00e+004.4721322
GO:0051084'de novo' posttranslational protein folding4.41e-021.00e+004.4721422
GO:0000387spliceosomal snRNP assembly4.41e-021.00e+004.4721122
GO:0008380RNA splicing4.42e-021.00e+002.565221165
GO:00063707-methylguanosine mRNA capping4.81e-021.00e+004.3471524
GO:0008180COP9 signalosome4.81e-021.00e+004.3471624
GO:0010827regulation of glucose transport5.00e-021.00e+004.2881725
GO:0000976transcription regulatory region sequence-specific DNA binding5.00e-021.00e+004.2881325
GO:0009267cellular response to starvation5.20e-021.00e+004.2311126
GO:0005057receptor signaling protein activity5.20e-021.00e+004.2311226
GO:0016032viral process5.48e-021.00e+001.775330428
GO:0016567protein ubiquitination5.58e-021.00e+002.377214188
GO:0006418tRNA aminoacylation for protein translation5.78e-021.00e+004.0731429
GO:0000737DNA catabolic process, endonucleolytic5.78e-021.00e+004.0731229
GO:0006446regulation of translational initiation5.78e-021.00e+004.0731229
GO:0090305nucleic acid phosphodiester bond hydrolysis6.17e-021.00e+003.9771631
GO:0007077mitotic nuclear envelope disassembly6.36e-021.00e+003.9311932
GO:0000122negative regulation of transcription from RNA polymerase II promoter6.39e-021.00e+001.684329456
GO:0000786nucleosome6.74e-021.00e+003.8441234
GO:0007254JNK cascade6.74e-021.00e+003.8441134
GO:0050434positive regulation of viral transcription6.94e-021.00e+003.8021535
GO:0044297cell body6.94e-021.00e+003.8021535
GO:0008645hexose transport7.13e-021.00e+003.7621836
GO:0003743translation initiation factor activity7.32e-021.00e+003.7221837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.51e-021.00e+003.6841438
GO:0048511rhythmic process7.51e-021.00e+003.6841538
GO:0003684damaged DNA binding8.08e-021.00e+003.5741141
GO:0000724double-strand break repair via homologous recombination8.27e-021.00e+003.5391542
GO:0001570vasculogenesis8.83e-021.00e+003.4401245
GO:0000502proteasome complex9.21e-021.00e+003.3771347
GO:0003682chromatin binding9.30e-021.00e+001.954215252
GO:0015758glucose transport9.39e-021.00e+003.3471848
GO:0001558regulation of cell growth9.58e-021.00e+003.3171249
GO:0006310DNA recombination9.77e-021.00e+003.2881850
GO:0006334nucleosome assembly9.95e-021.00e+003.2591451
GO:0005643nuclear pore9.95e-021.00e+003.25911251
GO:0006368transcription elongation from RNA polymerase II promoter1.01e-011.00e+003.2311852
GO:0006338chromatin remodeling1.07e-011.00e+003.1501755
GO:0008584male gonad development1.11e-011.00e+003.0991157
GO:0042826histone deacetylase binding1.12e-011.00e+003.0731558
GO:0000785chromatin1.14e-011.00e+003.0491659
GO:0006464cellular protein modification process1.18e-011.00e+003.0011461
GO:0046872metal ion binding1.18e-011.00e+001.064424934
GO:0030018Z disc1.23e-011.00e+002.9311364
GO:0030308negative regulation of cell growth1.34e-011.00e+002.8021370
GO:0051082unfolded protein binding1.34e-011.00e+002.8021570
GO:0001889liver development1.36e-011.00e+002.7821471
GO:0051726regulation of cell cycle1.39e-011.00e+002.7421373
GO:0001649osteoblast differentiation1.41e-011.00e+002.7221574
GO:0071456cellular response to hypoxia1.45e-011.00e+002.6841276
GO:0042127regulation of cell proliferation1.52e-011.00e+002.6101480
GO:0005215transporter activity1.55e-011.00e+002.5741582
GO:0005635nuclear envelope1.57e-011.00e+002.5561683
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.59e-011.00e+002.5391584
GO:0044267cellular protein metabolic process1.61e-011.00e+001.472214352
GO:0000209protein polyubiquitination1.73e-011.00e+002.4081692
GO:0006511ubiquitin-dependent protein catabolic process1.73e-011.00e+002.4081692
GO:0006260DNA replication1.76e-011.00e+002.3771994
GO:0045893positive regulation of transcription, DNA-templated1.79e-011.00e+001.373221377
GO:0000086G2/M transition of mitotic cell cycle1.81e-011.00e+002.3321797
GO:0006457protein folding1.81e-011.00e+002.3321597
GO:0006413translational initiation1.85e-011.00e+002.3021699
GO:0042981regulation of apoptotic process2.06e-011.00e+002.12414112
GO:0031965nuclear membrane2.35e-011.00e+001.90918130
GO:0016874ligase activity2.60e-011.00e+001.742111146
GO:0001701in utero embryonic development2.73e-011.00e+001.66517154
GO:0005874microtubule2.86e-011.00e+001.583110163
GO:0016071mRNA metabolic process2.96e-011.00e+001.522110170
GO:0005829cytosol2.97e-011.00e+000.4505881787
GO:0019221cytokine-mediated signaling pathway2.99e-011.00e+001.505110172
GO:0003677DNA binding3.06e-011.00e+000.629352947
GO:0006412translation3.08e-011.00e+001.456112178
GO:0008152metabolic process3.14e-011.00e+001.42416182
GO:0005975carbohydrate metabolic process3.20e-011.00e+001.392110186
GO:0016070RNA metabolic process3.22e-011.00e+001.377110188
GO:0005743mitochondrial inner membrane3.35e-011.00e+001.30919197
GO:0035556intracellular signal transduction3.38e-011.00e+001.29515199
GO:0030154cell differentiation3.45e-011.00e+001.25915204
GO:0019899enzyme binding3.53e-011.00e+001.21717210
GO:0007165signal transduction3.64e-011.00e+000.660224618
GO:0019901protein kinase binding3.82e-011.00e+001.07318232
GO:0008283cell proliferation3.91e-011.00e+001.03118239
GO:0006508proteolysis4.22e-011.00e+000.887111264
GO:0046982protein heterodimerization activity4.24e-011.00e+000.882111265
GO:0043565sequence-specific DNA binding4.36e-011.00e+000.82818275
GO:0006355regulation of transcription, DNA-templated4.36e-011.00e+000.450231715
GO:0008285negative regulation of cell proliferation4.38e-011.00e+000.818111277
GO:0008284positive regulation of cell proliferation4.40e-011.00e+000.80718279
GO:0008270zinc ion binding4.45e-011.00e+000.426239727
GO:0005737cytoplasm4.63e-011.00e+000.15461272633
GO:0005730nucleolus4.63e-011.00e+000.2673741217
GO:0044822poly(A) RNA binding4.96e-011.00e+000.289245799
GO:0055085transmembrane transport4.96e-011.00e+000.570113329
GO:0048471perinuclear region of cytoplasm5.12e-011.00e+000.505111344
GO:0005634nucleus5.17e-011.00e+000.07471583246
GO:0042802identical protein binding5.23e-011.00e+000.464115354
GO:0005524ATP binding5.57e-011.00e+000.131237892
GO:0006915apoptotic process5.77e-011.00e+000.248115411
GO:0006351transcription, DNA-templated6.64e-011.00e+00-0.1402471076
GO:0005887integral component of plasma membrane7.03e-011.00e+00-0.23618575
GO:0003700sequence-specific DNA binding transcription factor activity7.08e-011.00e+00-0.253122582
GO:0016020membrane7.27e-011.00e+00-0.3062561207
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.45e-011.00e+00-0.399129644
GO:0044281small molecule metabolic process8.36e-011.00e+00-0.790135844
GO:0070062extracellular vesicular exosome8.73e-011.00e+00-0.7492511641
GO:0016021integral component of membrane9.67e-011.00e+00-1.6441191526
GO:0005886plasma membrane9.82e-011.00e+00-1.8691461784