reg-snw-84108

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.199 2.91e-07 4.71e-02 3.57e-02
chia-screen-data-Fav-reg-snw-84108 subnetwork

Genes (30)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
CENPA 1058 27-2.1852.393205TFYes-
PHB2 11331 17-2.2362.44911-Yes-
FOXM1 2305 9-1.6692.412210TF--
WDR18 57418 5-1.3212.225213TF--
PHB 5245 82-2.7432.68936-YesYes
[ PCGF6 ] 84108 1-0.5302.1991TF--
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
EXO1 9156 3-1.5212.312159TF--
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
FBXL6 26233 28-2.2532.68922-Yes-
SYNCRIP 10492 42-2.4012.503144TFYesYes
SUV39H2 79723 27-2.3072.41021-YesYes
UBE2T 29089 2-1.7462.22342---
COPS3 8533 8-1.8732.43579TF--
SHFM1 7979 7-2.3662.3893-Yes-
TRAIP 10293 13-2.5462.45430TFYes-
FTSJ1 24140 43-2.4632.68935-YesYes
CENPQ 55166 20-2.1372.45916-Yes-
CCT7 10574 40-2.3352.45938-Yes-
EIF2B3 8891 8-2.5462.4354-YesYes
C16orf13 84326 12-2.0902.49236-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
ZNRD1 30834 3-1.3752.226106TF--
POLH 5429 36-2.5862.45924-YesYes
PSPH 5723 14-2.0632.38711-Yes-
ZNHIT3 9326 4-2.0852.2766-Yes-
TMEM14B 81853 3-2.8792.2261-YesYes

Interactions (51)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FOXM1 2305 EXO1 9156 pd <> reg.ITFP.txt: no annot
PHB 5245 WDR18 57418 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
FTSJ1 24140 WDR18 57418 pd < reg.ITFP.txt: no annot
GPS1 2873 WDR18 57418 pd <> reg.ITFP.txt: no annot
CENPA 1058 FBXL6 26233 pd > reg.ITFP.txt: no annot
FOXM1 2305 UBE2T 29089 pd > reg.ITFP.txt: no annot
UBE2T 29089 WDR18 57418 pd < reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
FOXM1 2305 SHFM1 7979 pd > reg.ITFP.txt: no annot
CCT7 10574 ZNRD1 30834 pd < reg.ITFP.txt: no annot
CENPA 1058 FOXM1 2305 pd <> reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
CENPA 1058 EXO1 9156 pd <> reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
FBXO22 26263 UBE2T 29089 pd > reg.ITFP.txt: no annot
CENPA 1058 ZNRD1 30834 pd <> reg.ITFP.txt: no annot
FBXO22 26263 WDR18 57418 pd <> reg.ITFP.txt: no annot
ZNRD1 30834 TMEM14B 81853 pd > reg.ITFP.txt: no annot
EXO1 9156 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
UBE2T 29089 ZNRD1 30834 pd < reg.ITFP.txt: no annot
CENPA 1058 SUV39H2 79723 pd > reg.ITFP.txt: no annot
UBE2T 29089 PCGF6 84108 pd < reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
PHB 5245 ZNRD1 30834 pd < reg.ITFP.txt: no annot
EXO1 9156 SUV39H2 79723 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 WDR18 57418 pd <> reg.ITFP.txt: no annot
FOXM1 2305 TRAIP 10293 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
GPS1 2873 C16orf13 84326 pd > reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
ZNHIT3 9326 WDR18 57418 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
CCT7 10574 WDR18 57418 pd < reg.ITFP.txt: no annot
EXO1 9156 UBE2T 29089 pd > reg.ITFP.txt: no annot
FOXM1 2305 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
WDR18 57418 C16orf13 84326 pd > reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
COPS3 8533 EIF2B3 8891 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB2 11331 ZNRD1 30834 pd < reg.ITFP.txt: no annot
VARS 7407 WDR18 57418 pd <> reg.ITFP.txt: no annot
FBXL6 26233 WDR18 57418 pd < reg.ITFP.txt: no annot
CENPA 1058 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB2 11331 pd > reg.ITFP.txt: no annot
COPS3 8533 UBE2T 29089 pd > reg.ITFP.txt: no annot
CENPA 1058 UBE2T 29089 pd > reg.ITFP.txt: no annot

Related GO terms (257)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010388cullin deneddylation2.53e-041.00e+006.347248
GO:0000775chromosome, centromeric region2.58e-041.00e+004.5743641
GO:0005654nucleoplasm9.15e-041.00e+001.742968876
GO:0008135translation factor activity, nucleic acid binding9.35e-041.00e+005.4402415
GO:0034080CENP-A containing nucleosome assembly1.68e-031.00e+005.0252220
GO:0004842ubiquitin-protein transferase activity2.06e-031.00e+002.863417179
GO:0008180COP9 signalosome2.41e-031.00e+004.7622624
GO:0045892negative regulation of transcription, DNA-templated2.55e-031.00e+002.360517317
GO:0004832valine-tRNA ligase activity3.07e-031.00e+008.347111
GO:00353125'-3' exodeoxyribonuclease activity3.07e-031.00e+008.347111
GO:0002128tRNA nucleoside ribose methylation3.07e-031.00e+008.347111
GO:0051908double-stranded DNA 5'-3' exodeoxyribonuclease activity3.07e-031.00e+008.347111
GO:0008175tRNA methyltransferase activity3.07e-031.00e+008.347111
GO:0000939condensed chromosome inner kinetochore3.07e-031.00e+008.347111
GO:0006438valyl-tRNA aminoacylation3.07e-031.00e+008.347111
GO:0048256flap endonuclease activity3.07e-031.00e+008.347111
GO:0006281DNA repair3.25e-031.00e+002.681424203
GO:0003743translation initiation factor activity5.68e-031.00e+004.1372837
GO:0045145single-stranded DNA 5'-3' exodeoxyribonuclease activity6.14e-031.00e+007.347112
GO:0048742regulation of skeletal muscle fiber development6.14e-031.00e+007.347112
GO:0051716cellular response to stimulus6.14e-031.00e+007.347112
GO:0004647phosphoserine phosphatase activity6.14e-031.00e+007.347112
GO:0005846nuclear cap binding complex6.14e-031.00e+007.347112
GO:0002176male germ cell proliferation6.14e-031.00e+007.347112
GO:2000781positive regulation of double-strand break repair6.14e-031.00e+007.347112
GO:0005850eukaryotic translation initiation factor 2 complex9.19e-031.00e+006.762123
GO:0036123histone H3-K9 dimethylation9.19e-031.00e+006.762113
GO:0000778condensed nuclear chromosome kinetochore9.19e-031.00e+006.762123
GO:0006563L-serine metabolic process9.19e-031.00e+006.762113
GO:0071459protein localization to chromosome, centromeric region9.19e-031.00e+006.762113
GO:0006334nucleosome assembly1.06e-021.00e+003.6742451
GO:0045292mRNA cis splicing, via spliceosome1.22e-021.00e+006.347114
GO:0097452GAIT complex1.22e-021.00e+006.347124
GO:0031442positive regulation of mRNA 3'-end processing1.22e-021.00e+006.347114
GO:0006290pyrimidine dimer repair1.22e-021.00e+006.347124
GO:0032057negative regulation of translational initiation in response to stress1.22e-021.00e+006.347114
GO:0006333chromatin assembly or disassembly1.22e-021.00e+006.347114
GO:0036124histone H3-K9 trimethylation1.22e-021.00e+006.347124
GO:0006564L-serine biosynthetic process1.22e-021.00e+006.347114
GO:0005851eukaryotic translation initiation factor 2B complex1.22e-021.00e+006.347124
GO:0071156regulation of cell cycle arrest1.22e-021.00e+006.347124
GO:0016779nucleotidyltransferase activity1.22e-021.00e+006.347114
GO:0060762regulation of branching involved in mammary gland duct morphogenesis1.22e-021.00e+006.347114
GO:0090344negative regulation of cell aging1.53e-021.00e+006.025115
GO:0035519protein K29-linked ubiquitination1.53e-021.00e+006.025125
GO:0070934CRD-mediated mRNA stabilization1.53e-021.00e+006.025125
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.53e-021.00e+006.025115
GO:0006282regulation of DNA repair1.53e-021.00e+006.025125
GO:0060744mammary gland branching involved in thelarche1.53e-021.00e+006.025115
GO:0032873negative regulation of stress-activated MAPK cascade1.53e-021.00e+006.025115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.53e-021.00e+006.025115
GO:0044314protein K27-linked ubiquitination1.53e-021.00e+006.025125
GO:0002161aminoacyl-tRNA editing activity1.53e-021.00e+006.025115
GO:0071204histone pre-mRNA 3'end processing complex1.53e-021.00e+006.025115
GO:0004523RNA-DNA hybrid ribonuclease activity1.53e-021.00e+006.025115
GO:0050847progesterone receptor signaling pathway1.83e-021.00e+005.762126
GO:0002181cytoplasmic translation1.83e-021.00e+005.762116
GO:0043566structure-specific DNA binding1.83e-021.00e+005.762116
GO:0042754negative regulation of circadian rhythm1.83e-021.00e+005.762126
GO:0085020protein K6-linked ubiquitination1.83e-021.00e+005.762126
GO:0046974histone methyltransferase activity (H3-K9 specific)1.83e-021.00e+005.762116
GO:0070937CRD-mediated mRNA stability complex1.83e-021.00e+005.762126
GO:0016446somatic hypermutation of immunoglobulin genes1.83e-021.00e+005.762116
GO:0002455humoral immune response mediated by circulating immunoglobulin1.83e-021.00e+005.762116
GO:0046578regulation of Ras protein signal transduction1.83e-021.00e+005.762116
GO:0002199zona pellucida receptor complex2.13e-021.00e+005.539147
GO:0007140male meiosis2.13e-021.00e+005.539117
GO:0000731DNA synthesis involved in DNA repair2.13e-021.00e+005.539117
GO:0006301postreplication repair2.13e-021.00e+005.539127
GO:00084095'-3' exonuclease activity2.13e-021.00e+005.539127
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway2.13e-021.00e+005.539127
GO:0000339RNA cap binding2.13e-021.00e+005.539117
GO:0000780condensed nuclear chromosome, centromeric region2.13e-021.00e+005.539117
GO:0005832chaperonin-containing T-complex2.13e-021.00e+005.539147
GO:0051382kinetochore assembly2.13e-021.00e+005.539127
GO:0001649osteoblast differentiation2.15e-021.00e+003.1372574
GO:0005845mRNA cap binding complex2.43e-021.00e+005.347118
GO:0006450regulation of translational fidelity2.43e-021.00e+005.347118
GO:0035102PRC1 complex2.43e-021.00e+005.347118
GO:0010944negative regulation of transcription by competitive promoter binding2.43e-021.00e+005.347118
GO:0030529ribonucleoprotein complex2.60e-021.00e+002.9892582
GO:0010225response to UV-C2.73e-021.00e+005.177129
GO:0006379mRNA cleavage2.73e-021.00e+005.177129
GO:0071354cellular response to interleukin-62.73e-021.00e+005.177119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.73e-021.00e+005.177129
GO:0032039integrator complex2.73e-021.00e+005.177119
GO:0005736DNA-directed RNA polymerase I complex3.03e-021.00e+005.0251410
GO:0005095GTPase inhibitor activity3.03e-021.00e+005.0251110
GO:0008143poly(A) binding3.03e-021.00e+005.0251210
GO:0009416response to light stimulus3.03e-021.00e+005.0251110
GO:0001054RNA polymerase I activity3.03e-021.00e+005.0251410
GO:0060766negative regulation of androgen receptor signaling pathway3.33e-021.00e+004.8871411
GO:0008652cellular amino acid biosynthetic process3.33e-021.00e+004.8871211
GO:0008334histone mRNA metabolic process3.33e-021.00e+004.8871111
GO:0000132establishment of mitotic spindle orientation3.63e-021.00e+004.7621212
GO:0004527exonuclease activity3.63e-021.00e+004.7621412
GO:0006413translational initiation3.68e-021.00e+002.7172699
GO:0005515protein binding3.77e-021.00e+000.507181984124
GO:0045190isotype switching3.92e-021.00e+004.6461113
GO:0060749mammary gland alveolus development3.92e-021.00e+004.6461113
GO:2000377regulation of reactive oxygen species metabolic process3.92e-021.00e+004.6461113
GO:0000738DNA catabolic process, exonucleolytic3.92e-021.00e+004.6461113
GO:0003723RNA binding3.93e-021.00e+001.983322247
GO:0003682chromatin binding4.13e-021.00e+001.954315252
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator4.22e-021.00e+004.5391114
GO:0016575histone deacetylation4.22e-021.00e+004.5391214
GO:0000188inactivation of MAPK activity4.51e-021.00e+004.4401115
GO:0014003oligodendrocyte development4.51e-021.00e+004.4401115
GO:0007339binding of sperm to zona pellucida4.51e-021.00e+004.4401415
GO:0003887DNA-directed DNA polymerase activity4.81e-021.00e+004.3471216
GO:0005739mitochondrion4.82e-021.00e+001.304532659
GO:0007049cell cycle4.83e-021.00e+002.50128115
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.92e-021.00e+001.514429456
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription5.10e-021.00e+004.2591217
GO:0006513protein monoubiquitination5.10e-021.00e+004.2591117
GO:0006298mismatch repair5.10e-021.00e+004.2591117
GO:0031667response to nutrient levels5.10e-021.00e+004.2591217
GO:0031047gene silencing by RNA5.39e-021.00e+004.1771218
GO:0033574response to testosterone5.39e-021.00e+004.1771118
GO:0031519PcG protein complex5.39e-021.00e+004.1771318
GO:0000398mRNA splicing, via spliceosome5.84e-021.00e+002.347215128
GO:0006913nucleocytoplasmic transport5.97e-021.00e+004.0251220
GO:0070979protein K11-linked ubiquitination5.97e-021.00e+004.0251320
GO:0046966thyroid hormone receptor binding5.97e-021.00e+004.0251320
GO:0071346cellular response to interferon-gamma5.97e-021.00e+004.0251220
GO:0051321meiotic cell cycle5.97e-021.00e+004.0251120
GO:0005720nuclear heterochromatin5.97e-021.00e+004.0251320
GO:0071897DNA biosynthetic process5.97e-021.00e+004.0251220
GO:0034660ncRNA metabolic process5.97e-021.00e+004.0251120
GO:0006363termination of RNA polymerase I transcription6.26e-021.00e+003.9541321
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic6.26e-021.00e+003.9541221
GO:0006139nucleobase-containing compound metabolic process6.55e-021.00e+003.8871222
GO:0030331estrogen receptor binding6.55e-021.00e+003.8871222
GO:0051084'de novo' posttranslational protein folding6.55e-021.00e+003.8871422
GO:0000387spliceosomal snRNP assembly6.55e-021.00e+003.8871122
GO:0000278mitotic cell cycle7.06e-021.00e+001.637328314
GO:0044212transcription regulatory region DNA binding7.10e-021.00e+002.187213143
GO:00063707-methylguanosine mRNA capping7.13e-021.00e+003.7621524
GO:0070534protein K63-linked ubiquitination7.13e-021.00e+003.7621324
GO:0000976transcription regulatory region sequence-specific DNA binding7.41e-021.00e+003.7031325
GO:0009267cellular response to starvation7.70e-021.00e+003.6461126
GO:0005057receptor signaling protein activity7.70e-021.00e+003.6461226
GO:0010467gene expression7.91e-021.00e+001.283449535
GO:0001701in utero embryonic development8.07e-021.00e+002.08027154
GO:0016881acid-amino acid ligase activity8.27e-021.00e+003.5391328
GO:0006418tRNA aminoacylation for protein translation8.55e-021.00e+003.4891429
GO:0000737DNA catabolic process, endonucleolytic8.55e-021.00e+003.4891229
GO:0006446regulation of translational initiation8.55e-021.00e+003.4891229
GO:0008380RNA splicing9.08e-021.00e+001.980221165
GO:0051865protein autoubiquitination9.11e-021.00e+003.3921231
GO:0009408response to heat9.11e-021.00e+003.3921131
GO:0090305nucleic acid phosphodiester bond hydrolysis9.11e-021.00e+003.3921631
GO:0045111intermediate filament cytoskeleton9.11e-021.00e+003.3921331
GO:0044267cellular protein metabolic process9.22e-021.00e+001.472314352
GO:0017148negative regulation of translation9.67e-021.00e+003.3021533
GO:0000786nucleosome9.95e-021.00e+003.2591234
GO:0007254JNK cascade9.95e-021.00e+003.2591134
GO:0050434positive regulation of viral transcription1.02e-011.00e+003.2171535
GO:0031124mRNA 3'-end processing1.02e-011.00e+003.2171435
GO:0070936protein K48-linked ubiquitination1.02e-011.00e+003.2171135
GO:0044297cell body1.02e-011.00e+003.2171535
GO:0006412translation1.03e-011.00e+001.871212178
GO:0043434response to peptide hormone1.05e-011.00e+003.1771136
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process1.11e-011.00e+003.0991438
GO:0006369termination of RNA polymerase II transcription1.11e-011.00e+003.0991538
GO:0048511rhythmic process1.11e-011.00e+003.0991538
GO:0016567protein ubiquitination1.13e-011.00e+001.792214188
GO:0006396RNA processing1.16e-011.00e+003.0251440
GO:0003684damaged DNA binding1.19e-011.00e+002.9891141
GO:0000724double-strand break repair via homologous recombination1.21e-011.00e+002.9541542
GO:0005743mitochondrial inner membrane1.22e-011.00e+001.72429197
GO:0005085guanyl-nucleotide exchange factor activity1.24e-011.00e+002.9201243
GO:0006406mRNA export from nucleus1.27e-011.00e+002.8871744
GO:0009749response to glucose1.30e-011.00e+002.8551145
GO:0001570vasculogenesis1.30e-011.00e+002.8551245
GO:0009612response to mechanical stimulus1.32e-011.00e+002.8231246
GO:0000502proteasome complex1.35e-011.00e+002.7921347
GO:0001558regulation of cell growth1.40e-011.00e+002.7321249
GO:0016032viral process1.42e-011.00e+001.190330428
GO:0006310DNA recombination1.43e-011.00e+002.7031850
GO:0006368transcription elongation from RNA polymerase II promoter1.48e-011.00e+002.6461852
GO:0006338chromatin remodeling1.56e-011.00e+002.5651755
GO:0016311dephosphorylation1.56e-011.00e+002.5651355
GO:0005737cytoplasm1.60e-011.00e+000.443111272633
GO:0008584male gonad development1.61e-011.00e+002.5141157
GO:0042826histone deacetylase binding1.64e-011.00e+002.4891558
GO:0000785chromatin1.66e-011.00e+002.4641659
GO:0005829cytosol1.69e-011.00e+000.5438881787
GO:0071013catalytic step 2 spliceosome1.72e-011.00e+002.4161561
GO:0006464cellular protein modification process1.72e-011.00e+002.4161461
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding1.77e-011.00e+002.3691263
GO:0030018Z disc1.79e-011.00e+002.3471364
GO:0008270zinc ion binding1.81e-011.00e+000.841439727
GO:0003676nucleic acid binding1.84e-011.00e+002.3021466
GO:0030308negative regulation of cell growth1.94e-011.00e+002.2171370
GO:0051082unfolded protein binding1.94e-011.00e+002.2171570
GO:0001889liver development1.97e-011.00e+002.1971471
GO:0016363nuclear matrix2.02e-011.00e+002.15711073
GO:0051726regulation of cell cycle2.02e-011.00e+002.1571373
GO:0071456cellular response to hypoxia2.09e-011.00e+002.0991276
GO:0042127regulation of cell proliferation2.19e-011.00e+002.0251480
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.29e-011.00e+001.9541584
GO:0000209protein polyubiquitination2.48e-011.00e+001.8231692
GO:0006511ubiquitin-dependent protein catabolic process2.48e-011.00e+001.8231692
GO:0006260DNA replication2.52e-011.00e+001.7921994
GO:0000086G2/M transition of mitotic cell cycle2.59e-011.00e+001.7471797
GO:0006457protein folding2.59e-011.00e+001.7471597
GO:0005634nucleus2.72e-011.00e+000.267121583246
GO:0034641cellular nitrogen compound metabolic process2.77e-011.00e+001.63215105
GO:0006366transcription from RNA polymerase II promoter2.82e-011.00e+000.933223341
GO:0043547positive regulation of GTPase activity2.93e-011.00e+001.53912112
GO:0042981regulation of apoptotic process2.93e-011.00e+001.53914112
GO:0043005neuron projection2.95e-011.00e+001.52616113
GO:0007165signal transduction2.95e-011.00e+000.660324618
GO:0000287magnesium ion binding2.99e-011.00e+001.50114115
GO:0006974cellular response to DNA damage stimulus3.12e-011.00e+001.428111121
GO:0046872metal ion binding3.22e-011.00e+000.479424934
GO:0045893positive regulation of transcription, DNA-templated3.23e-011.00e+000.788221377
GO:0003677DNA binding3.31e-011.00e+000.459452947
GO:0031625ubiquitin protein ligase binding3.48e-011.00e+001.23817138
GO:0005622intracellular3.62e-011.00e+001.16712145
GO:0016874ligase activity3.64e-011.00e+001.157111146
GO:0006355regulation of transcription, DNA-templated3.78e-011.00e+000.450331715
GO:0005874microtubule3.97e-011.00e+000.998110163
GO:0016071mRNA metabolic process4.10e-011.00e+000.937110170
GO:0000166nucleotide binding4.21e-011.00e+000.887113176
GO:0006351transcription, DNA-templated4.25e-011.00e+000.2754471076
GO:0016070RNA metabolic process4.42e-011.00e+000.792110188
GO:0044822poly(A) RNA binding4.50e-011.00e+000.289345799
GO:0035556intracellular signal transduction4.61e-011.00e+000.71015199
GO:0030154cell differentiation4.70e-011.00e+000.67415204
GO:0043234protein complex4.80e-011.00e+000.632113210
GO:0019899enzyme binding4.80e-011.00e+000.63217210
GO:0007275multicellular organismal development4.86e-011.00e+000.60519214
GO:0019901protein kinase binding5.14e-011.00e+000.48918232
GO:0005730nucleolus5.24e-011.00e+000.0974741217
GO:0005524ATP binding5.25e-011.00e+000.131337892
GO:0008283cell proliferation5.25e-011.00e+000.44618239
GO:0003700sequence-specific DNA binding transcription factor activity5.41e-011.00e+000.162222582
GO:0006508proteolysis5.61e-011.00e+000.302111264
GO:0046982protein heterodimerization activity5.62e-011.00e+000.297111265
GO:0043565sequence-specific DNA binding5.76e-011.00e+000.24318275
GO:0008285negative regulation of cell proliferation5.79e-011.00e+000.233111277
GO:0008284positive regulation of cell proliferation5.81e-011.00e+000.22218279
GO:0048471perinuclear region of cytoplasm6.60e-011.00e+00-0.080111344
GO:0005509calcium ion binding6.67e-011.00e+00-0.10919351
GO:0042802identical protein binding6.70e-011.00e+00-0.121115354
GO:0005783endoplasmic reticulum6.98e-011.00e+00-0.227112381
GO:0006915apoptotic process7.25e-011.00e+00-0.336115411
GO:0042803protein homodimerization activity7.40e-011.00e+00-0.395113428
GO:0005887integral component of plasma membrane8.39e-011.00e+00-0.82118575
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.71e-011.00e+00-0.984129644
GO:0016020membrane9.00e-011.00e+00-0.8912561207
GO:0070062extracellular vesicular exosome9.01e-011.00e+00-0.7493511641
GO:0044281small molecule metabolic process9.34e-011.00e+00-1.375135844
GO:0016021integral component of membrane9.94e-011.00e+00-2.2291191526
GO:0005886plasma membrane9.98e-011.00e+00-2.4541461784